result 964 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchiyama, Takaki| Goto, Hidenori| Uesugi, Eri| Takai, Akihisa| Zhi, Lei| Miura, Akari| Hamao, Shino| Eguchi, Ritsuko| Ota, Hiromi| Sugimoto, Kunihisa| Fujiwara, Akihiko| Matsui, Fumihiko| Kimura, Koji| Hayashi, Kouichi| Ueno, Teppei| Kobayashi, Kaya| Akimitsu, Jun| Kubozono, Yoshihiro| |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-27701-5| |
| Published Date | 2023-01-11 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | nature portfolio |
| Start Page | 537 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 36631625 |
| DOI | 10.1038/s41598-023-27701-5 |
| Web of Science KeyUT | 000986510100067 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-023-27701-5 |
| JaLCDOI | 10.18926/AMO/65493 |
|---|---|
| FullText URL | 77_3_281.pdf |
| Author | Mukai, Yuko| Taira, Naruto| Kajiwara, Yukiko| Iwamoto, Takayuki| Kitaguchi, Yohei| Saiga, Miho| Watanabe, Satoko| Shien, Tadahiko| Doihara, Hiroyoshi| Kimata, Yoshihiro| |
| Abstract | Although immediate breast reconstruction following mastectomy has become increasingly common, its oncological safety has been debated. We enrolled patients with breast cancer who underwent surgery at Okayama University Hospital between 2007 and 2013. The primary outcome was relapse-free survival (RFS). Secondary outcomes were overall survival and the duration from the surgery to the initiation of adjuvant chemotherapy. We divided into immediate breast reconstruction, mastectomy alone, and breast conservative surgery groups. Outcomes were compared using Cox’s regression analysis. A total of 614 patients were included (reconstruction: 125, mastectomy: 128, breast conservative surgery: 361). The median follow-up duration was 79.0±31.9 months. The immediate-reconstruction patients were younger, had more lymph node metastases, and more often received postoperative chemotherapy. The RFS was better after the breast conservative surgery compared to after reconstruction (hazard ratio 0.33, 95% confidence interval: 0.144-0.763). The proportion of local recurrence was highest in the reconstruction group. No patients in the reconstruction group underwent postoperative radiation therapy. However, reconstruction did not affect overall survival or the time to the initiation of adjuvant chemotherapy. Surgeons should explain the risks of breast reconstruction to their patients preoperatively. Careful long-term follow-up is required after such procedures. |
| Keywords | immediate breast reconstruction oncological safety local recurrence postoperative radiation therapy time to initiation of adjuvant chemotherapy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 281 |
| End Page | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357629 |
| Web of Science KeyUT | 001026279600006 |
| JaLCDOI | 10.18926/AMO/65492 |
|---|---|
| FullText URL | 77_3_273.pdf |
| Author | Shimizu, Yudai| Kuroda, Masahiro| Nakamitsu, Yuki| Al-Hammad, Wlla E.| Yoshida, Suzuka| Fukumura, Yuka| Nakamura, Yoshihide| Kuroda, Kazuhiro| Kamizaki, Ryo| Imajoh, Satoshi| Tanabe, Yoshinori| Sugimoto, Kohei| Oita, Masataka| Sugianto, Irfan| Bamgbose, Babatunde O.| Yanagi, Yoshinobu| Asaumi, Junichi| |
| Abstract | Diffusion kurtosis (DK) imaging (DKI), a type of restricted diffusion-weighted imaging, has been reported to be useful for tumor diagnoses in clinical studies. We developed a software program to simultaneously create DK images with apparent diffusion coefficient (ADC) maps and conducted an initial clinical study. Multi-shot echo-planar diffusion-weighted images were obtained at b-values of 0, 400, and 800 sec/mm2 for simple DKI, and DK images were created simultaneously with the ADC map. The usefulness of the DK image and ADC map was evaluated using a pixel analysis of all pixels and a median analysis of the pixels of each case. Tumor and normal tissues differed significantly in both pixel and median analyses. In the pixel analysis, the area under the curve was 0.64 for the mean kurtosis (MK) value and 0.77 for the ADC value. In the median analysis, the MK value was 0.74, and the ADC value was 0.75. The MK and ADC values correlated moderately in the pixel analysis and strongly in the median analysis. Our simple DKI system created DK images simultaneously with ADC maps, and the obtained MK and ADC values were useful for differentiating head and neck tumors from normal tissue. |
| Keywords | simple diffusion kurtosis imaging mean kurtosis clinical trial head and neck tumor magnetic resonance imaging |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 273 |
| End Page | 280 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357628 |
| Web of Science KeyUT | 001026279600005 |
| JaLCDOI | 10.18926/AMO/65488 |
|---|---|
| FullText URL | 77_3_235.pdf |
| Author | Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki| |
| Abstract | Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users. |
| Keywords | anamorelin body weight cancer cachexia endocrine system |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 235 |
| End Page | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357624 |
| Web of Science KeyUT | 001026279600001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Inaba, Mototaka| Naito, Hiromichi| Yorifuji, Takashi| Nakamichi, Chikaaki| Maeyama, Hiroki| Ishikawa, Hideki| Shime, Nobuaki| Uemori, Sadayori| Ishihara, Satoshi| Takaoka, Makoto| Ohtsuka, Tsuyoshi| Harada, Masahiro| Nozaki, Satoshi| Kohama, Keisuke| Sakurai, Ryota| Sato, Shuho| Muramatsu, Shun| Yamashita, Kazunori| Mayumi, Toshihiko| Aita, Kaoruko| Nakao, Atsunori| the LIFE Study Investigators| |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-32519-2| |
| Published Date | 2023-04-03 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | nature portfolio |
| Start Page | 5433 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37012346 |
| DOI | 10.1038/s41598-023-32519-2 |
| Web of Science KeyUT | 000984090500023 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-023-32519-2 |
| Title Alternative | ERRATA: FDM simulation of long-period ground motions around Oita Prefecture, Japan, using a land-ocean unified 3D structure model |
|---|---|
| FullText URL | esr_029_065_066.pdf |
| Author | OKUNAKA, Tatsuya| KOMATSU, Masanao| TAKENAKA, Hiroshi| YOSHIMI, Masayuki| NAKAMURA, Takeshi| OKAMOTO, Taro| |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2023-03-31 |
| Volume | volume29 |
| Issue | issue1 |
| Start Page | 65 |
| End Page | 66 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2023 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| JaLCDOI | 10.18926/interdisciplinary/65468 |
|---|---|
| Title Alternative | Advanced Hospital Training Activities in Fiscal 2022 |
| FullText URL | interdisciplinary_3_75.pdf |
| Author | MORITA, Mizuki| KANAYAMA, Naoki| AIDA, Toshiaki| WATANABE, Toyohiko| YAMASHITA, Noboru| HAKAMADA, Rei| YOSHIBA, Yasuyuki| |
| Publication Title | Interdisciplinary Science |
| Published Date | 2023-03-31 |
| Volume | volume3 |
| Start Page | 75 |
| End Page | 82 |
| ISSN | 2436-3227 |
| language | Japanese |
| File Version | publisher |
| FullText URL | O0004551‗fulltext.pdf O0004551_abstract_review.pdf O0004551_summary.pdf |
|---|---|
| Author | HIRAMI, Yuki| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4551号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy in Health Sciences |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2022 by The Japanese Society for Lymphoreticular Tissue Research |
| FullText URL | K0006864_abstract_review.pdf K0006864_fulltext.pdf |
|---|---|
| Author | WANG, Yongdong| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6864号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006847_abstract_review.pdf K0006847_fulltext.pdf |
|---|---|
| Author | SOLDATOV, ALEXANDER| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6847号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006798_abstract_review.pdf K0006798_fulltext.pdf K0006798_summary.pdf |
|---|---|
| Author | TSUDAKA, Shimpei| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6798号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © Society of Surgical Oncology 2021 |
| FullText URL | fulltext20230530-01.pdf |
|---|---|
| Author | Shigehira, Takafumi| Hanafusa, Tadashi| Igawa, Kazuyo| Kasai, Tomonari| Furuya, Shuichi| Nishimori, Hisakazu| Maeda, Yoshinobu| Michiue, Hiroyuki| Fujimura, Atsushi| |
| Keywords | boron agents boron neutron capture therapy simulation study |
| Note | This is the peer reviewed version of the following article: T. Shigehira, T. Hanafusa, K. Igawa, T. Kasai, S. Furuya, H. Nishimori, Y. Maeda, H. Michiue, A. Fujimura, Particle and Heavy Ion Transport Code System-Based Microdosimetry for the Development of Boron Agents for Boron Neutron Capture Therapy. Adv. Theory Simul. 2023, 6, 2300163. https://doi.org/10.1002/adts.202300163, which has been published in final form at https://doi.org/10.1002/adts.202300163. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Apr. 2024.| |
| Published Date | 2023-04-28 |
| Publication Title | Advanced Theory and Simulations |
| Volume | volume6 |
| Issue | issue7 |
| Publisher | Wiley |
| Start Page | 2300163 |
| ISSN | 2513-0390 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Wiley-VCH GmbH |
| File Version | author |
| DOI | 10.1002/adts.202300163 |
| Web of Science KeyUT | 000978086700001 |
| Related Url | isVersionOf https://doi.org/10.1002/adts.202300163 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yoshihara, Kumiko| Nagaoka, Noriyuki| Makita, Yoji| Yoshida, Yasuhiro| Van Meerbeek, Bart| |
| Keywords | biofilm cetylpyridinium chloride montmorillonite PMMA resin cement antibacterial agents dentin bond strength |
| Published Date | 2023-04-27 |
| Publication Title | Nanomaterials |
| Volume | volume13 |
| Issue | issue9 |
| Publisher | MDPI |
| Start Page | 1495 |
| ISSN | 2079-4991 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37177041 |
| DOI | 10.3390/nano13091495 |
| Web of Science KeyUT | 000986817700001 |
| Related Url | isVersionOf https://doi.org/10.3390/nano13091495 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fujimoto, Ryohei| Suzuki, Etsuji| Kashima, Saori| Nakamura, Kazufumi| Naito, Hiromichi| Nakao, Atsunori| Ito, Hiroshi| Yorifuji, Takashi| |
| Keywords | cardiovascular disease climate change end of the rainy season heat exposure |
| Published Date | 2023-03-21 |
| Publication Title | Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease |
| Volume | volume12 |
| Issue | issue6 |
| Publisher | Wiley |
| Start Page | e027046 |
| ISSN | 2047-9980 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 36892062 |
| DOI | 10.1161/JAHA.122.027046 |
| Web of Science KeyUT | 000956680700026 |
| Related Url | isVersionOf https://doi.org/10.1161/JAHA.122.027046 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Arias, Zulema| Nizami, Mohammed Zahedul Islam| Chen, Xiaoting| Chai, Xinyi| Xu, Bin| Kuang, Canyan| Omori, Kazuhiro| Takashiba, Shogo| |
| Keywords | apical periodontitis contemporary approaches nonsurgical endodontic treatment immune inflammatory disease alternative treatments |
| Published Date | 2023-04-19 |
| Publication Title | Bioengineering |
| Volume | volume10 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 488 |
| ISSN | 2306-5354 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37106675 |
| DOI | 10.3390/bioengineering10040488 |
| Web of Science KeyUT | 000977447300001 |
| Related Url | isVersionOf https://doi.org/10.3390/bioengineering10040488 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yumoto, Tetsuya| Hongo, Takashi| Hifumi, Toru| Inoue, Akihiko| Sakamoto, Tetsuya| Kuroda, Yasuhiro| Yorifuji, Takashi| Nakao, Atsunori| Naito, Hiromichi| SAVE-J II study group| |
| Published Date | 2023-04-11 |
| Publication Title | Journal of the American College of Emergency Physicians Open |
| Volume | volume4 |
| Issue | issue2 |
| Publisher | Wiley |
| Start Page | e12948 |
| ISSN | 2688-1152 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 37064164 |
| DOI | 10.1002/emp2.12948 |
| Web of Science KeyUT | 000969175200001 |
| Related Url | isVersionOf https://doi.org/10.1002/emp2.12948 |
| Title Alternative | Experience with a nosocomial cluster of novel coronavirus infection and the cluster response algorithm |
|---|---|
| FullText URL | 135_22.pdf |
| Author | Fujita, Koji| Ocho, Kazuki| Kadowaki, Tomoka| Yorifuji, Takashi| Otsuka, Fumio| |
| Abstract | The novel coronavirus disease (COVID-19) pandemic that began in 2019 is yet to end, as of the summer of 2022. During the pandemic, community-acquired infections spread easily to healthcare-associated facilities, resulting in COVID-19 clusters among high-risk individuals that have been difficult to contain. Our regional base hospital also experienced a nosocomial cluster of COVID-19 in October 2020 that took 30 days to contain and affected 9 hospital staff and 14 patients. Six patients died due to COVID-19, and six died due to COVID-19-related complications. Two patients were discharged alive. Patient characteristics included ① advanced age (79.0±8.1 years), ② dementia (64.3%), ③ low Prognostic Nutrition Index (31.1 ±7.9), ④ zinc deficiency (50.2±13.1μg/dL), ⑤ vitamin C deficiency (1.6±1.9μg/mL), ⑥ elevated urea nitrogen-to-creatinine ratio (27.4±23.5), ⑦ anticancer and immunosuppressive drug use (78.6%), and ⑧ malignancy (75.6%). This cluster had a very high mortality rate, but the viral spread was contained in a short period. Algorithmizing the cluster response was crucial to controlling this cluster. We report on our actual cluster response algorithm, as well as our strategy and response procedure during the pandemic. |
| Keywords | 新型コロナウイルス感染症 (COVID-19) 院内クラスター (nosocomial cluster) 対応アルゴリズム (response algorithm) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2023-04-01 |
| Volume | volume135 |
| Issue | issue1 |
| Start Page | 22 |
| End Page | 33 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.135.22 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2023 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.135.22 |
| JaLCDOI | 10.18926/AMO/65152 |
|---|---|
| FullText URL | 77_2_209.pdf |
| Author | Sakamoto, Masaki| Teraishi, Fuminori| Shigeyasu Kunitoshi| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Abstract | A 70-year-old male with anal pain and fever was diagnosed with rectal cancer perforation and abscess in the right gluteus maximus (GM) muscle. He underwent a transverse colon colostomy followed by preoperative capecitabine+oxaliplatin. Some local control was achieved but a residual abscess was observed in the right GM muscle. To secure circumferential resection margin by tumor reduction, he received chemoradiotherapy as total neoadjuvant therapy (TNT) and underwent laparoscopic abdominoperineal resection, D3 lymph node dissection, combined coccyx resection, and partial resection of the right GM muscle. The skin defect and pelvic dead space were filled with a right lateral vastus lateral great muscle flap. Histopathologically, the resected specimen showed no tumor cells in the primary tumor or lymph nodes, indicating a pathological complete response (pCR). This case suggests that TNT might improve the R0 resection and pCR rates and overall survival. |
| Keywords | locally advanced rectal cancer total neoadjuvant therapy lateral vastus lateral great muscle flap |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 209 |
| End Page | 213 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094960 |
| Web of Science KeyUT | 000982563800003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Wang, Han| Salaipeth, Lakha| Miyazaki, Naoyuki| Suzuki, Nobuhiro| Okamoto, Kenta| |
| Published Date | 2023-02-27 |
| Publication Title | PLoS Pathogens |
| Volume | volume19 |
| Issue | issue2 |
| Publisher | Public Library of Science |
| Start Page | e1011162 |
| ISSN | 1553-7366 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Wang et al. |
| File Version | publisher |
| PubMed ID | 36848381 |
| DOI | 10.1371/journal.ppat.1011162 |
| Web of Science KeyUT | 000942039200002 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.ppat.1011162 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kojima, Keiichi| Sudo, Yuki| |
| Published Date | 2023-03-06 |
| Publication Title | RSC Advances |
| Volume | volume13 |
| Issue | issue11 |
| Publisher | Royal Society of Chemistry |
| Start Page | 7222 |
| End Page | 7224 |
| ISSN | 2046-2069 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Author(s). |
| File Version | publisher |
| PubMed ID | 36891494 |
| DOI | 10.1039/d3ra90016a |
| Web of Science KeyUT | 000943987600001 |
| Related Url | isVersionOf https://doi.org/10.1039/d3ra90016a |
