JaLCDOI 10.18926/AMO/31575
フルテキストURL fulltext.pdf
著者 Ozaki, Toshifumi| Sugihara, Shinsuke| Inoue, Hajime|
抄録

We report second malignant neoplasms which developed between 7 and 19 years after treatment in 3 pediatric patients with osteosarcoma. Two patients had been treated with only surgery, and another patient had been treated with a combination of surgery with chemotherapy and radiation therapy for primary lesions. Pediatric patients with osteosarcoma, in particular, require careful long-term follow-up to monitor not only metastases but also development of second malignant neoplasms.

キーワード osteosarcoma second malignancy
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1993-04
47巻
2号
出版者 Okayama University Medical School
開始ページ 129
終了ページ 133
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 8506750
Web of Science KeyUT A1993LA45200010
JaLCDOI 10.18926/AMO/54980
フルテキストURL 71_2_119.pdf
著者 Oda, Yoshiaki| Takigawa, Tomoyuki| Sugimoto, Yoshihisa| Tanaka, Masato| Akazawa, Hirofumi| Ozaki, Toshifumi|
抄録 Patients with cerebral palsy (CP) frequently present with scoliosis; however, the pattern of curve progression is difficult to predict. We aimed to clarify the natural course of the progression of scoliosis and to identify scoliosis predictors. This was a retrospective, single-center, observational study. Total of 92 CP patients from Asahikawasou Ryouiku Iryou Center in Okayama, Japan were retrospectively analyzed. Cobb angle, presence of hip dislocation and pelvic obliquity, and Gross Motor Function Classification System (GMFCS) were investigated. Severe CP was defined as GMFCS level IV or V. The mean observation period was 10.7 years. Thirtyfour severe CP patients presented with scoliosis and were divided into 3 groups based on their clinical courses: severe, moderate and mild. The mean Cobb angles at the final follow-up were 129°, 53°, and 13° in the severe, moderate, and mild groups, respectively. The average progressions from 18 to 25 years were 2.7°/year, 0.7°/year, and 0.1°/year in the severe, moderate, and mild curve groups, respectively. We observed the natural course of scoliosis and identified 3 courses based on the Cobb angle at 15 and 18 years of age. This method of classification may help clinicians predict the patients’ disease progression.
キーワード severe cerebral palsy scoliosis natural course Cobb angle progression
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-04
71巻
2号
出版者 Okayama University Medical School
開始ページ 119
終了ページ 126
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28420893
著者 Furumatsu, Takayuki| Shukunami, Chisa| Amemiya-Kudo, Michiyo| Shimano, Hitoshi| Ozaki, Toshifumi|
発行日 2010-01
出版物タイトル The International Journal of Biochemistry & Cell Biology
42巻
1号
資料タイプ 学術雑誌論文
フルテキストURL fulltext.pdf
著者 Katayama, Haruyoshi| Fujimura, Atsushi| Huang, Rongsheng| Otani, Yusuke| Itano, Takuto| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Nakata, Eiji| Ozaki, Toshifumi|
キーワード benserazide cancer stem cell catecholamine synthase malignant peripheral nerve sheath tumor Schwann cell vesicular monoamine transporter
発行日 2024-01-26
出版物タイトル Cancer Science
115巻
3号
出版者 Wiley
開始ページ 871
終了ページ 882
ISSN 1347-9032
NCID AA11808050
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 The Authors.
論文のバージョン publisher
PubMed ID 38279513
DOI 10.1111/cas.16077
Web of Science KeyUT 001149722500001
関連URL isVersionOf https://doi.org/10.1111/cas.16077
フルテキストURL fulltext.pdf
著者 Fujiwara, Tomohiro| Healey, John| Ogura, Koichi| Yoshida, Aki| Kondo, Hiroya| Hata, Toshiaki| Kure, Miho| Tazawa, Hiroshi| Nakata, Eiji| Kunisada, Toshiyuki| Fujiwara, Toshiyoshi| Ozaki, Toshifumi|
キーワード sarcoma tumor-associated macrophage prognosis clinical trial immunotherapy
発行日 2021-03-03
出版物タイトル Cancers
13巻
5号
出版者 MDPI
開始ページ 1086
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 33802565
DOI 10.3390/cancers13051086
NAID 120007008531
Web of Science KeyUT 000627955600001
関連URL isVersionOf https://doi.org/10.3390/cancers13051086
フルテキストURL fulltext.pdf
著者 Nakata, Eiji| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Nakahara, Ryuichi| Katayama, Haruyoshi| Itano, Takuto| Ozaki, Toshifumi|
キーワード Soft tissue sarcomas Forearm Function Prognosis
備考 The version of record of this article, first published in Journal of Orthopaedic Surgery and Research, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13018-023-04088-7|
発行日 2023-08-14
出版物タイトル Journal of Orthopaedic Surgery and Research
18巻
1号
出版者 BMC
開始ページ 599
ISSN 1749-799X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023.
論文のバージョン publisher
PubMed ID 37580775
DOI 10.1186/s13018-023-04088-7
Web of Science KeyUT 001049196400001
関連URL isVersionOf https://doi.org/10.1186/s13018-023-04088-7
著者 Nishida, Keiichiro| Hashizume, Kenzo| Ozawa, Masatsugu| Takeshita, Ayumu| Kaneda, Daisuke| Nakahara, Ryuichi| Nasu, Yoshihisa| Shimamura, Yasunori| Inoue, Hajime| Ozaki, Toshifumi|
発行日 2017-02
出版物タイトル Acta Medica Okayama
71巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/54824
JaLCDOI 10.18926/AMO/55308
フルテキストURL 71_4_315.pdf
著者 Fujii, Yosuke| Endo, Hirosuke| Mitani, Shigeru| Akazawa, Hirofumi| Tetsunaga, Tomonori| Miyake, Takamasa| Yamada, Kazuki| Aoki, Kiyoshi| Ozaki, Toshifumi|
抄録 We retrospectively reviewed 29 hips in which intertrochanteric osteotomies were performed for severe slipped capital femoral epiphyses. Mean age at surgery: 12.6 years. Mean follow-up period: 6 years. At the final follow-up evaluation, one patient had coxalgia, and six hips showed a limited range of motion. A pistol-grip deformity was observed in 13 hips, osteoarthritis in two hips, and a bump existed in 19 hips on the latest radiographs. Gradual remodeling of the bumps was observed post-operatively in 22 hips. The mean α and β angles and offset α and β improved over time. The remodeling proceeded rapidly for 1 year post-surgery. We compared hips classified as β angles of ≥ 63° to < 63° at the final follow-up evaluation, the mean β angle 1 year post-surgery, and the mean ratio of improvement of the β angle per year from 1 year post-surgery to the final follow up, which differed significantly. Nearly all of the patients who underwent intertrochanteric osteotomies had residual morphologic abnormalities, but few had clinical symptoms. The β angle 1 year post-surgery and the ratio of remodeling of the bump from 1 year post-surgery to the final follow-up can be regarded as a potential predictor of morphologic results after intertrochanteric osteotomy.
キーワード slipped capital femoral epiphyses intertrochanteric osteotomy residual femoral deformity femoroacetabular impingement bone remodeling
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-08
71巻
4号
出版者 Okayama University Medical School
開始ページ 315
終了ページ 323
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28824187
フルテキストURL fulltext.pdf
著者 Ise, Masato| Saito, Taichi| Katayama, Yoshimi| Nakahara, Ryuichi| Shimamura, Yasunori| Hamada, Masanori| Senda, Masuo| Ozaki, Toshifumi|
キーワード Carpal tunnel syndrome Nerve conduction study The disability of the arm shoulder and hand questionnaire Clinical outcomes
発行日 2021-10-16
出版物タイトル BMC Musculoskeletal Disorders
22巻
1号
出版者 BMC
開始ページ 882
ISSN 1471-2474
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2021.
論文のバージョン publisher
PubMed ID 34656102
DOI 10.1186/s12891-021-04771-y
Web of Science KeyUT 000707702900001
関連URL isVersionOf https://doi.org/10.1186/s12891-021-04771-y
JaLCDOI 10.18926/AMO/49043
フルテキストURL 66_6_469.pdf
著者 Shiozaki, Yasuyuki| Ito, Yasuo| Sugimoto, Yoshihisa| Tomioka, Masao| Shimokawa, Tetsuya| Mazaki, Tetsuro| Koshimune, Koichiro| Tanaka, Masato| Ozaki, Toshifumi|
抄録 In this study, we studied the relationship between fracture patterns and motor function recovery in 70 consecutive patients with cervical spinal cord injury. Fractures were categorized into 6 fracture types and subdivided into stages according to the Allen-Ferguson classification system:compressive flexion (CF), distractive flexion (DF), compressive extension (CE), distractive extension (DE), vertical compression (VC) and lateral flexion (LF). Paralysis was evaluated using the American Spinal Injury Association (ASIA) impairment scale at the time of injury and 3 months afterwards. The residual rate of complete motor palsy (ASIA grade A or B) at the final examination was higher in those patients with DE fractures than those with CF, DF or CE. The final outcomes were as follows. Of the 14 patients who were classified with CF fractures, residual palsy was frequently seen in patients who had stage 5 injury. Of the 27 patients with DF fractures, residual palsy occurred in about half of the patients who had stage 4 or 5 injury. Of the 18 patients with CE fractures, residual palsy occurred in half of the patients with stage 3 injury or higher. Finally, of the 7 patients with DE fractures, the rate of residual palsy was high even for the stage 1 and 2 cases;indeed, all DE patients who had complete motor palsy at the first examination had residual palsy at the final examination. Accordingly, we conclude that motor recovery may be related to fracture pattern.
キーワード cervical spinal cord injury motor function recovery fracture patterns
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2012-12
66巻
6号
出版者 Okayama University Medical School
開始ページ 469
終了ページ 473
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23254581
Web of Science KeyUT 000312966100006
JaLCDOI 10.18926/AMO/31335
フルテキストURL fulltext.pdf
著者 Ozaki, Toshifumi| Nakatsuka, Yoichi| Kawai, Akira| Akazawa, Hirofumi| Kunisada, Toshiyuki| Inoue, Hajime|
抄録

There are few reports on skeletal reconstruction using the bone transport technique to repair bone defects caused by resections of tumors associated with osteosarcoma. We attempted to reconstruct a 23 cm bone defect after resection of an osteosarcoma of the left femur, and succeeded in gaining 17 cm by bone transport. Five years after surgery, this patient remains alive without metastasis or local recurrence.

キーワード osteosarcoma bone transport reconstruction
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1998-02
52巻
1号
出版者 Okayama University Medical School
開始ページ 67
終了ページ 70
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 9548997
Web of Science KeyUT 000072264100010
JaLCDOI 10.18926/AMO/31340
フルテキストURL fulltext.pdf
著者 Ozaki, Toshifumi| Nakatsuka, Yoichi| Kawai, Akira| Akazawa, Hirofumi| Kunisada, Toshiyuki| Inoue, Hajime|
抄録

There are few reports on skeletal reconstruction using the bone transport technique to repair bone defects caused by resections of tumors associated with osteosarcoma. We attempted to reconstruct a 23 cm bone defect after resection of an osteosarcoma of the left femur, and succeeded in gaining 17 cm by bone transport. Five years after surgery, this patient remains alive without metastasis or local recurrence.

キーワード osteosarcoma bone transport reconstruction
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1998-02
52巻
1号
出版者 Okayama University Medical School
開始ページ 67
終了ページ 70
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 9548997
Web of Science KeyUT 000072264100010
JaLCDOI 10.18926/AMO/32654
フルテキストURL fulltext.pdf
著者 Ozaki, Toshifumi| Inoue, Hajime| Sugihara, Shinsuke| Sumii, Hiroshi|
抄録

Radiological findings on the fate of grafted Kiel bone implants for the treatment of bone tumors were evaluated in 25 lesions. The mean follow-up period was 14.8 years, ranging from 5 to 21.8 years. We classified the radiological findings into 4 grades; Excellent (4 lesions), Good (14 lesions), Fair (2 lesions), and Poor (5 lesions). All cases of the Poor grade were polyostotic fibrous dysplasia. The younger the patient at the time of the operation, the more rapidly Kiel bone grafts tended to be incorporated. The grafted bone can become enmeshed in the structure of the recipient bed (Good or Excellent grades) within 10 years in most cases, except in polyostotic fibrous dysplasia.

キーワード xenogeneic bone bone grafting bone neoplasms
Amo Type Article
出版物タイトル Acta Medica Okayama
発行日 1992-04
46巻
2号
出版者 Okayama University Medical School
開始ページ 87
終了ページ 92
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 1575062
Web of Science KeyUT A1992HR48400005
JaLCDOI 10.18926/AMO/31814
フルテキストURL fulltext.pdf
著者 Minagawa, Hiroshi| Aiga, Ayako| Endo, Hirosuke| Mitani, Shigeru| Tetsunaga, Tomonori| Ozaki, Toshifumi|
抄録

This retrospective study assessed the radiographic results of 16 patients with avascular necrosis following treatment for developmental dislocation of the hip (DDH) who were subsequently treated between 1991 and 2005 by rotation acetabular osteotomy (RAO) combined with femoral intertrochan-teric osteotomy (FIO). Initial treatment was by Pavlik harness, cast fixation, or overhead traction. The parameters that showed consistent improvement were the index of centralization, the index of acetabular coverage, adequate reduction of the greater trochanter, and abductor sufficiency. The combined procedure appears to be effective in cases in which preoperative planning shows a reasonable expectation of congruency and osteoarthritis is limited to the early stages.

キーワード rotation acetabular osteotomy femoral intertrochanteric osteotomy combined procedure developmental dysplasia of hip avascular necrosis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2009-08
63巻
4号
出版者 Okayama University Medical School
開始ページ 169
終了ページ 175
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 19727201
Web of Science KeyUT 000269228400002
フルテキストURL fulltext.pdf
著者 Kunisada, Toshiyuki| Hasei, Joe| Fujiwara, Tomohiro| Nakata, Eiji| Yokoo, Suguru| Demiya, Koji| Ozaki, Toshifumi|
発行日 2020-12-09
出版物タイトル Scientific Reports
10巻
1号
出版者 Nature Research
開始ページ 21578
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020
論文のバージョン publisher
PubMed ID 33299043
DOI 10.1038/s41598-020-78409-9
Web of Science KeyUT 000608956800002
関連URL isVersionOf https://doi.org/10.1038/s41598-020-78409-9
フルテキストURL fulltext.pdf
著者 Kunisada, Toshiyuki| Nakata, Eiji| Fujiwara, Tomohiro| Katayama, Haruyoshi| Itano, Takuto| Kurozumi, Takanao| Ando, Teruhiko| Ozaki, Toshifumi|
キーワード unidirectional porous beta-tricalcium phosphate bone tumor bone graft radiography bone remodeling
発行日 2025-02-10
出版物タイトル Biomimetics
10巻
2号
出版者 MDPI
開始ページ 101
ISSN 2313-7673
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2025 by the authors.
論文のバージョン publisher
PubMed ID 39997124
DOI 10.3390/biomimetics10020101
Web of Science KeyUT 001430456900001
関連URL isVersionOf https://doi.org/10.3390/biomimetics10020101
JaLCDOI 10.18926/AMO/31850
フルテキストURL fulltext.pdf
著者 Ohmori, Takao| Endo, Hirosuke| Mitani, Shigeru| Minagawa, Hiroshi| Tetsunaga, Tomonori| Ozaki, Toshifumi|
抄録

In 1957, Pavlik introduced the Pavlik harness as a useful treatment for developmental dislocation of the hip (DDH), and subsequent studies have documented favorable outcomes among patients treated with this device. However, there are only a few articles reporting how early radiographic measurements can be used to determine the prognosis after treatment with the Pavlik harness. In this study, 217 hips from 192 patients whose DDH treatment with the Pavlik harness was initiated before they were 6 months old and whose follow-up lasted at least 14 years (rate, 63.8%) were analyzed using measurements from radiographs taken immediately before and after harness treatment, and at 1, 2, and 3 years of age. Severin's classification at the final follow-up was I or II in 71.9% and III or IV in 28.1% of the hips, respectively. Avascular necrosis of the femoral head (AVN) was seen in 10% of the hips. Stepwise multiple regression analysis was performed to retrospectively determine whether any radiographic factors were related to the final classification as Severin I/II or III/IV. Receiver opera-ting characteristic (ROC) curves were drawn for these factors, and a Wiberg OE angle (Point O was the middle point of the proximal metaphyseal border of the femur) of 2 degrees on the 3-year radiographs was found to be the most useful screening value for judging the acetabular development of DDH cases after treatment with a Pavlik harness, with a sensitivity of 71% a specificity of 93%, and a likelihood ratio of 10.1.

キーワード developmental dislocation of the hip long-term follow up radiographic measurement stepwise multiple regression analysis acetabular development
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2009-06
63巻
3号
出版者 Okayama University Medical School
開始ページ 123
終了ページ 128
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
論文のバージョン publisher
査読 有り
PubMed ID 19571898
Web of Science KeyUT 000267388200001
フルテキストURL J_Orthop_Sci_21_4_524.pdf fig.pdf
著者 Furumatsu, Takayuki| Maehara, Ami| Ozaki, Toshifumi|
備考 This is an Accepted Manuscript of an article published by Elsevier|
発行日 2016-07
出版物タイトル Journal of Orthopaedic Science
21巻
4号
出版者 Elsevier
開始ページ 524
終了ページ 529
ISSN 0949-2658
NCID AA11052566
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 27113646
DOI 10.1016/j.jos.2016.02.013
Web of Science KeyUT 000381142800020
関連URL isVersionOf https://doi.org/10.1016/j.jos.2016.02.013
フルテキストURL fulltext.pdf
著者 Takeshita, Ayumu| Nishida, Keiichiro| Yoshida, Aki| Nasu, Yoshihisa| Nakahara, Ryuichi| Kaneda, Daisuke| Ohashi, Hideki| Ozaki, Toshifumi|
発行日 2021-07-07
出版物タイトル PLOS ONE
16巻
7号
出版者 Public Library Science
開始ページ e0254268
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Takeshita et al.
論文のバージョン publisher
PubMed ID 34234380
DOI 10.1371/journal.pone.0254268
Web of Science KeyUT 000674294100020
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0254268
フルテキストURL fulltext.pdf
著者 Tsuji, Hironori| Misawa, Haruo| Takigawa, Tomoyuki| Tetsunaga, Tomoko| Yamane, Kentaro| Oda, Yoshiaki| Ozaki, Toshifumi|
発行日 2021-01-27
出版物タイトル Scientific Reports
11巻
1号
出版者 Nature Research
開始ページ 2284
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2021
論文のバージョン publisher
PubMed ID 33504836
DOI 10.1038/s41598-021-81874-5
Web of Science KeyUT 000668339700002
関連URL isVersionOf https://doi.org/10.1038/s41598-021-81874-5