JaLCDOI | 10.18926/AMO/30974 |
---|---|
フルテキストURL | fulltext.pdf |
著者 | Ikuma, Hisanori| Abe, Nobuhiro| Uchida, Youichiro| Furumatsu, Takayuki| Fujiwara, Kazuo| Nishida, Keiichiro| Ozaki, Toshifumi| |
抄録 | <p>Instability of the knee after the medial collateral ligament (MCL) injury is usually assessed with the manual valgus stress test, even though, in recent years, it has become possible to apply magnetic resonance imaging (MRI) to the assessment of the damage of the ligament. The valgus instability of 24 patients (12 isolated injuries and 12 multiple ligament injuries) who suffered MCL injury between 1993 and 1998 was evaluated with the Hughston and Eilers classification, which involves radiographic assessment under manual valgus stress to the injured knees. We developed a novel system for classifying the degree of injury to the MCL by calculating the percentage of injured area based on MRI and investigated the relationship between this novel MRI classification and the magnitude of valgus instability by the Hughston and Eilers classification. There was a significant correlation between the 2 classifications (p=0.0006). On the other hand, the results using other MRI based classification systems, such as the Mink and Deutsch classificaiton and the Petermann classification, were not correlated with the findings by the Hughston and Eilers classification in these cases (p0.05). Since MRI is capable of assessing the injured ligament in clinical practice, this novel classification system would be useful for evaluating the stability of the knee and choosing an appropriate treatment following MCL injury.</p> |
キーワード | medial collateral ligament magnetic resonance imaging knee instability novel method |
Amo Type | Original Article |
発行日 | 2008-06 |
出版物タイトル | Acta Medica Okayama |
巻 | 62巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 185 |
終了ページ | 191 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | English |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 18596835 |
Web of Science KeyUT | 000257130300006 |
JaLCDOI | 10.18926/AMO/40007 |
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フルテキストURL | fulltext.pdf |
著者 | Furumatsu, Takayuki| Ozaki, Toshifumi| |
抄録 | Epigenetics is an essential mechanism to control gene expression and fundamental cellular processes. DNA methylation in CpG-rich promoters correlates with gene silencing. Histone modification including histone acetylation and deacetylation determines the stability of the chromatin structure. Condensed chromatin (heterochromatin), which has a higher-order histone-DNA structure, prevents the access of transcriptional activators to their target genes. The fundamental unit of eukaryotic chromatin consists of 146 bp of DNA wrapped around a histone octamer. Posttranslational modifications of the histone tail and the chromatin remodeling complex disrupt histone-DNA contacts and induce nucleosome mobilization. Histone acetylation of specific lysine residues in the histone tail plays a crucial role in epigenetic regulation. Histone acetylation is a dynamic process regulated by the antagonistic actions of 2 families of enzymes - the histone acetyltransferases (HATs) and the histone deacetylases (HDACs). The balance between histone acetylation and deacetylation serves as a key epigenetic mechanism for transcription factor-dependent gene expression and the developmental process. We review emerging evidence that DNA methylation, histone acetylation modified by HAT and/or HDAC, and transcription factor-associated molecules contribute to a mechanism that can alter chromatin structure, gene expression, and cellular differentiation during chondrogenesis. |
キーワード | epigenetics DNA methylation histone acetylation and HAT histone deacetylation and HDAC chondrogenesis |
Amo Type | Review |
発行日 | 2010-06 |
出版物タイトル | Acta Medica Okayama |
巻 | 64巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 155 |
終了ページ | 161 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | English |
著作権者 | Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 20596126 |
Web of Science KeyUT | 000279094300001 |
著者 | 古松 毅之| 尾﨑 敏文| 浅原 弘嗣| |
---|---|
発行日 | 2010-08-02 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 122巻 |
号 | 2号 |
資料タイプ | 学術雑誌論文 |
著者 | 藤原 一夫| 遠藤 裕介| 三宅 由晃| 尾﨑 敏文| |
---|---|
発行日 | 2010-08-02 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 122巻 |
号 | 2号 |
資料タイプ | 学術雑誌論文 |
著者 | Miyake, Yoshiaki| Furumatsu, Takayuki| Kubota, Satoshi| Kawata, Kazumi| Ozaki, Toshifumi| Takigawa, Masaharu| |
---|---|
発行日 | 2011-06-03 |
出版物タイトル | Biochemical and Biophysical Research Communications |
巻 | 409巻 |
号 | 2号 |
資料タイプ | 学術雑誌論文 |
著者 | Saiga, Kenta| Furumatsu, Takayuki| Yoshida, Aki| Masuda, Shin| Takihira, Shota| Abe, Nobuhiro| Ozaki, Toshifumi| |
---|---|
発行日 | 2010-11-12 |
出版物タイトル | Biochemical and Biophysical Research Communications |
巻 | 402巻 |
号 | 2号 |
資料タイプ | 学術雑誌論文 |
著者 | Furumatsu, Takayuki| Hachioji, Motomi| Saiga, Kenta| Takata, Naoki| Yokoyama, Yusuke| Ozaki, Toshifumi| |
---|---|
発行日 | 2010-01-01 |
出版物タイトル | Biochemical and Biophysical Research Communications |
巻 | 391巻 |
号 | 1号 |
資料タイプ | 学術雑誌論文 |
著者 | Furumatsu, Takayuki| Shukunami, Chisa| Amemiya-Kudo, Michiyo| Shimano, Hitoshi| Ozaki, Toshifumi| |
---|---|
発行日 | 2010-01 |
出版物タイトル | The International Journal of Biochemistry & Cell Biology |
巻 | 42巻 |
号 | 1号 |
資料タイプ | 学術雑誌論文 |
著者 | Furumatsu, Takayuki| Ozaki, Toshifumi| Asahara, Hiroshi| |
---|---|
発行日 | 2009-05 |
出版物タイトル | The International Journal of Biochemistry & Cell Biology |
巻 | 41巻 |
号 | 5号 |
資料タイプ | 学術雑誌論文 |
著者 | Tetsunaga, Tomonori| Furumatsu, Takayuki| Abe, Nobuhiro| Nishida, Keiichiro| Naruse, Keiji| Ozaki, Toshifumi| |
---|---|
発行日 | 2009-09-18 |
出版物タイトル | Journal of Biomechanics |
巻 | 42巻 |
号 | 13号 |
資料タイプ | 学術雑誌論文 |
著者 | Furumatsu, Takayuki| Matsumoto, Emi| Kanazawa, Tomoko| Fujii, Masataka| Lu, Zhichao| Kajiki, Ryotaro| Ozaki, Toshifumi| |
---|---|
発行日 | 2013-05-31 |
出版物タイトル | Journal of Biomechanics |
巻 | 46巻 |
号 | 9号 |
資料タイプ | 学術雑誌論文 |
JaLCDOI | 10.18926/AMO/52786 |
---|---|
フルテキストURL | 68_4_201.pdf |
著者 | Endo, Hirosuke| Akazawa, Hirofumi| Mitani, Shigeru| Okada, Yoshiki| Yamane, Kentaro| Ozaki, Toshifumi| |
抄録 | We reviewed the treatment outcome in 14 hips of 7 patients who were diagnosed as having bilateral developmental dislocation of the hip (DDH) after walking age and could be followed up until they were at least 14 years of age. Based on the results of two-directional arthrography of the hip, closed reduction was performed in 2 hips, and open reduction was performed without osteotomy in 12 hips. The final radiographic evaluations were made according to the Kalamchi and MacEwen classification and Severin classification. The mean age at the initial visit was 1 year and 9 months (range, 1 year and 5 months to 3 years). The outcome was satisfactory for one hip in Group Ⅰ and 2 hips in Group Ⅱ according to the Kalamchi and MacEwen classification, and in 83% of the Severin Class Ⅰ and Ⅱ hips. Arthrography was useful for identifying asymmetry, demonstrating the usefulness of a treatment strategy based on arthrography of the hip. |
キーワード | developmental dislocation of the hip bilateral case arthrogram open reduction after walking age |
Amo Type | Original Article |
発行日 | 2014-08 |
出版物タイトル | Acta Medica Okayama |
巻 | 68巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 201 |
終了ページ | 206 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | English |
著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 25145406 |
Web of Science KeyUT | 000340687500002 |
JaLCDOI | 10.18926/AMO/54806 |
---|---|
フルテキストURL | 70_6_441.pdf |
著者 | Kashihara, Naoko| Furumatsu, Takayuki| Kodama, Yuya| Tanaka, Takaaki| Ozaki, Toshifumi| |
抄録 | Concurrent meniscal repair with anterior cruciate ligament (ACL) reconstruction has shown good clinical outcomes, but it has a considerable risk of progressing to post-traumatic osteoarthritis of the knee. Here we investigated postoperative changes in the position of the lateral meniscus (LM) and assessed the short-term clinical results after concurrent LM repair with ACL reconstruction. Twentyseven patients underwent LM repair of a peripheral longitudinal tear concomitant with ACL reconstruction. We evaluated the preoperative and postoperative values of the Lysholm score and anteroposterior instability. The length and width of the lateral tibial plateau were determined by radiographic images. The length, width, body width, extrusion, and height of the LM were measured in magnetic resonance images and compared between the preoperative and postoperative measurements. Our analysis revealed that concurrent LM repair with ACL reconstruction improved the shortterm clinical outcomes. Although the body width and height of the LM did not change, the postoperative LM extrusion and LM width were significantly increased after the surgery. The post-traumatic transposition of the LM may not be completely prevented by LM repair concomitant with ACL reconstruction. |
キーワード | lateral meniscus meniscal extrusion meniscal repair anterior cruciate ligament reconstruction |
Amo Type | Original Article |
発行日 | 2016-12 |
出版物タイトル | Acta Medica Okayama |
巻 | 70巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 441 |
終了ページ | 448 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | English |
著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 28003668 |
JaLCDOI | 10.18926/AMO/54818 |
---|---|
フルテキストURL | 70_6_515.pdf |
著者 | Fujii, Masataka| Furumatsu, Takayuki| Kadota, Yasutaka| Shimamura, Yoshinobu| Tsuchimochi, Shigeyuki| Ozaki, Toshifumi| |
抄録 | The present report describes the first known, case of a pseudoaneurysm of the perforating branch of the deep femoral artery following anterior cruciate ligament (ACL) reconstruction. A 19-year-old man underwent ACL reconstruction using the outside-in femoral tunnel-creation method. Seven days after the surgery, he complained of abnormal thigh pain and had swelling with local heat on the distal lateral thigh. Magnetic resonance imaging, computed tomography, and color Doppler ultrasonography showed the pseudoaneurysm in the thigh. Resection surgery was successfully performed by a vascular surgeon 12 days after ACL reconstruction. Careful examination and awareness of postoperative symptoms such as thigh pain and swelling after ACL reconstruction were critical for the early diagnosis of pseudoaneurysm. |
キーワード | pseudoaneurysm perforating branch of the deep femoral artery anterior cruciate ligament |
Amo Type | Case Report |
発行日 | 2016-12 |
出版物タイトル | Acta Medica Okayama |
巻 | 70巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 515 |
終了ページ | 518 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | English |
著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 28003680 |
フルテキストURL | J_Orthop_Sci_21_4_524.pdf fig.pdf |
---|---|
著者 | Furumatsu, Takayuki| Maehara, Ami| Ozaki, Toshifumi| |
備考 | This is an Accepted Manuscript of an article published by Elsevier| |
発行日 | 2016-07 |
出版物タイトル | Journal of Orthopaedic Science |
巻 | 21巻 |
号 | 4号 |
出版者 | Elsevier |
開始ページ | 524 |
終了ページ | 529 |
ISSN | 0949-2658 |
NCID | AA11052566 |
資料タイプ | 学術雑誌論文 |
言語 | English |
OAI-PMH Set | 岡山大学 |
著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
論文のバージョン | author |
PubMed ID | 27113646 |
DOI | 10.1016/j.jos.2016.02.013 |
Web of Science KeyUT | 000381142800020 |
関連URL | isVersionOf https://doi.org/10.1016/j.jos.2016.02.013 |
フルテキストURL | J_Orthop_Sci_22_4_715.pdf fig.pdf |
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著者 | Lu, Zhichao| Furumatsu, Takayuki| Fujii, Masataka| Maehara, Ami| Ozaki, Toshifumi| |
キーワード | vascular endothelial growth factor (VEGF) meniscus meniscal injury hypoxia-inducible factor-1α (HIF-1α) |
備考 | This is an Accepted Manuscript of an article published by Elsevier| |
発行日 | 2017-07 |
出版物タイトル | Journal of Orthopaedic Science |
巻 | 22巻 |
号 | 4号 |
出版者 | Elsevier |
開始ページ | 715 |
終了ページ | 721 |
ISSN | 0949-2658 |
NCID | AA11052566 |
資料タイプ | 学術雑誌論文 |
言語 | English |
OAI-PMH Set | 岡山大学 |
著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
論文のバージョン | author |
PubMed ID | 28318650 |
DOI | 10.1016/j.jos.2017.02.006 |
Web of Science KeyUT | 000407394700022 |
関連URL | isVersionOf https://doi.org/10.1016/j.jos.2017.02.006 |
フルテキストURL | J_Orthop_Sci_22_4_731.pdf fig.pdf tbl.pdf |
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著者 | Furumatsu, Takayuki| Fujii, Masataka| Kodama, Yuya| Ozaki, Toshifumi| |
備考 | This is an Accepted Manuscript of an article published by Elsevier| |
発行日 | 2017-07 |
出版物タイトル | Journal of Orthopaedic Science |
巻 | 22巻 |
号 | 4号 |
出版者 | Elsevier |
開始ページ | 731 |
終了ページ | 736 |
ISSN | 0949-2658 |
NCID | AA11052566 |
資料タイプ | 学術雑誌論文 |
言語 | English |
OAI-PMH Set | 岡山大学 |
著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
論文のバージョン | author |
PubMed ID | 28416188 |
DOI | 10.1016/j.jos.2017.03.013 |
Web of Science KeyUT | 000407394700025 |
関連URL | isVersionOf https://doi.org/10.1016/j.jos.2017.03.013 |
フルテキストURL | Knee26_3_653.pdf tables.pdf Fig.pdf |
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著者 | Furumatsu, Takayuki| Okazaki, Yuki| Kodama, Yuya| Okazaki, Yoshiki| Masuda, Shin| Kamatsuki, Yusuke| Takihira, Shota| Hiranaka, Takaaki| Yamawaki, Tadashi| Ozaki, Toshifumi| |
キーワード | Clinical outcome Medial meniscus Meniscal healing Posterior root tear Transtibial pullout repair |
発行日 | 2019-06-30 |
出版物タイトル | The Knee |
巻 | 26巻 |
号 | 3号 |
出版者 | Elsevier |
開始ページ | 653 |
終了ページ | 659 |
ISSN | 09680160 |
NCID | AA10996272 |
資料タイプ | 学術雑誌論文 |
言語 | English |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2019 Elsevier B.V. All rights reserved. |
論文のバージョン | author |
PubMed ID | 30902517 |
DOI | 10.1016/j.knee.2019.02.007 |
Web of Science KeyUT | 000474504500017 |
関連URL | isVersionOf https://doi.org/10.1016/j.knee.2019.02.007 |
JaLCDOI | 10.18926/AMO/57713 |
---|---|
フルテキストURL | 73_6_495.pdf |
著者 | Masuda, Shin| Furumatsu, Takayuki| Okazaki, Yoshiki| Kamatsuki, Yusuke| Okazaki, Yuki| Kodama, Yuya| Hiranaka, Takaaki| Nakata, Eiji| Ozaki, Toshifumi| |
抄録 | Medial meniscus posterior root tear causes rapid knee cartilage degradation by inducing posteromedial displacement of the medial meniscus. We evaluated medial meniscus posterior extrusion before and after pullout repair for medial meniscus posterior root tear using magnetic resonance images. Twenty-eight patients with symptomatic medial meniscus posterior root tear were included. The inclusion criteria were: acute (< 3 months) or chronic (≥3 months) medial meniscus posterior root tear after painful popping events. The exclusion criteria were: other meniscus and anterior cruciate ligament injuries. We measured medial meniscus posterior extrusion and medial meniscus anteroposterior interval at knee flexion angles of 10° and 90° preoperatively and at 3 months postoperatively. The posterior extrusion at 90° knee flexion decreased from 4.42±1.38 mm preoperatively to 3.09±1.06 mm (p<0.001) postoperatively, while at 10° knee flexion it was −4.17±1.63 mm preoperatively and −3.77±1.72mm postoperatively, showing no significant change. The anteroposterior interval at 10° knee flexion increased from 19.74±4.27 mm preoperatively to 22.15±5.10 mm postoperatively (p<0.001); at 90° knee flexion, it increased from 16.81±4.51 mm preoperatively to 19.20±4.30 mm postoperatively (p<0.001). Medial meniscus posterior extrusion and movement decreased after pullout repair. Pullout repair for medial meniscus posterior root tear improves medial meniscus posterior extrusion, especially at 90° knee flexion. |
キーワード | medial meniscus posterior root tear pullout repair extrusion open magnetic resonance imaging |
Amo Type | Original Article |
発行日 | 2019-12 |
出版物タイトル | Acta Medica Okayama |
巻 | 73巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 495 |
終了ページ | 501 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | English |
著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 31871331 |
Web of Science KeyUT | 000503431400004 |
フルテキストURL | fulltext.pdf |
---|---|
著者 | Hiranaka, Takaaki| Furumatsu, Takayuki| Tanaka, Takaaki| Okazaki, Yuki| Kodama, Yuya| Kamatsuki, Yusuke| Masuda, Kenji| Seno, Noritaka| Ozaki, Toshifumi| |
キーワード | anterior cruciate ligament knee pullout suture screw fixation tibial eminence avulsion fracture |
発行日 | 2020-06-03 |
出版物タイトル | Journal of Orthopaedic Surgery |
巻 | 28巻 |
号 | 2号 |
出版者 | SAGE Publications |
開始ページ | 2309499020918681 |
ISSN | 2309-4990 |
NCID | AA11004541 |
資料タイプ | 学術雑誌論文 |
言語 | English |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2020 |
論文のバージョン | publisher |
PubMed ID | 32489139 |
DOI | 10.1177/2309499020918681 |
Web of Science KeyUT | 000539749100001 |
関連URL | isVersionOf https://doi.org/10.1177/2309499020918681 |