検索結果 - 岡山大学学術成果リポジトリ

Vancomycin MIC creep progresses in methicillin-resistant Staphylococcus aureus despite the national antimicrobial stewardship campaign: Single facility data in Japan

フルテキストURL	fulltext20220715-1.pdf
著者	Fujimori, Takumi\| Hagiya, Hideharu\| Iio, Koji\| Higashionna, Tsukasa\| Kakehi, Ayaka\| Okura, Mami\| Minabe, Hiroshi\| Yokoyama, Yukika\| Otsuka, Fumio\| Higashikage, Akihito\|
キーワード	Antimicrobial resistance Methicillin-resistant Staphylococcus aureus Vancomycin Minimum inhibitory concentration Creep Antimicrobial resistance Methicillin-resistant Staphylococcus aureus Vancomycin Minimum inhibitory concentration Creep
備考	© 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jiac.2022.03.017] . \|
発行日	2022-07
出版物タイトル	Journal of Infection and Chemotherapy
巻	28巻
号	7号
出版者	Elsevier BV
開始ページ	918
終了ページ	922
ISSN	1341-321X
NCID	AA11057978
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases.
論文のバージョン	author
PubMed ID	35351391
DOI	10.1016/j.jiac.2022.03.017
Web of Science KeyUT	000806199400012
関連URL	isVersionOf https://doi.org/10.1016/j.jiac.2022.03.017

Diffuse myometrium thinning and placenta accreta spectrum in a patient with systemic lupus erythematosus (SLE): a case report and review of the literature

フルテキストURL	fulltext.pdf
著者	Mitoma, Tomohiro\| Hayata, Kei\| Yokohata, Satomi\| Ohira, Akiko\| Kashino, Chiaki\| Kirino, Satoe\| Tani, Kazumasa\| Maki, Jota\| Eto, Eriko\| Masuyama, Hisashi\|
キーワード	Lupus Myometrium Placenta accreta spectrum Estrogen Uterine atony
発行日	2022-07-02
出版物タイトル	BMC Pregnancy And Childbirth
巻	22巻
号	1号
出版者	BMC
開始ページ	535
ISSN	1471-2393
NCID	AA12035416
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	35780086
DOI	10.1186/s12884-022-04864-z
Web of Science KeyUT	000820223600001
関連URL	isVersionOf https://doi.org/10.1186/s12884-022-04864-z

Descending Colon Cancer Coincident with Schistosoma japonicum in an 89-year-old Male

JaLCDOI	10.18926/AMO/63748
フルテキストURL	76_3_355.pdf
著者	Teraishi, Fuminori\| Jikuhara, Atsushi\| Ogawa, Ryunosuke\| Fujiwara, Toshiyoshi\|
抄録	An 89-year-old male came to the hospital with a complaint of abdominal distension. Abdominal computed tomography showed wall thickening in the descending colon and marked dilatation of the proximal colon, and lower gastrointestinal endoscopy demonstrated a stenosis in the descending colon. Although a biopsy from the stenotic lesion showed calcified eggs of Schistosoma japonicum with no malignant findings, we suspected malignant involvement, so we performed a descending colectomy with regional lymph node dissection. Pathological examination revealed a moderately differentiated adenocarcinoma. The colon cancer was diagnosed as pT4bN0M0, Stage IIc. The patient’s history as a resident of one of the formerly endemic areas of Japan suggests that he may have carried S. japonicum for a long time, and that it may have contributed to carcinogenesis.
キーワード	Schistosoma japonicum descending colon cancer carcinogenesis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-06
巻	76巻
号	3号
出版者	Okayama University Medical School
開始ページ	355
終了ページ	358
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35790369
Web of Science KeyUT	000823568300017

Successful Treatment of Atypical Femoral Fracture with Bowed Femur Using Contralateral Intramedullary Nail Combined with Early Daily Teriparatide

JaLCDOI	10.18926/AMO/63744
フルテキストURL	76_3_333.pdf
著者	Akagawa, Manabu\| Miyakoshi, Naohisa\| Tsuchie, Hiroyuki\| Kasukawa, Yuji\| Kawaragi, Takashi\| Nagahata, Itsuki\| Suzuki, Masazumi\| Yoshikawa, Takayuki\| Abe, Toshiki\| Shimada, Yoichi\|
抄録	We report a case of atypical femoral fracture achieving early fracture union with combination therapy comprising contralateral nail and immediate teriparatide injection. Fracture union of atypical fractures is often delayed due to bowing deformity and bone metabolic disorders. Combination treatment that takes both problems into consideration represents a useful treatment option for atypical femoral fracture.
キーワード	atypical femoral fracture bowing deformity intramedullary nail teriparatide cephalomedullary screw
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2022-06
巻	76巻
号	3号
出版者	Okayama University Medical School
開始ページ	333
終了ページ	338
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35790365
Web of Science KeyUT	000823568300013

Evaluation of Fast Diffusion Kurtosis Imaging Using New Software Designed for Widespread Clinical Use

JaLCDOI	10.18926/AMO/63739
フルテキストURL	76_3_297.pdf
著者	Kuroda, Masahiro\| Konishi, Kohei\| Sugimoto, Kohei\| Yoshimura, Yuuki\| Hamada, Kentaro\| Khasawnehc, Abdullah\| Barham, Majd\| Tekiki, Nouha\| Sugianto, Irfan\| Bamgbose, Babatunde O.\| Ishizaka, Hinata\| Shimizu, Yudai\| Nakamitsu, Yuki\| Al-Hammad, Wlla E.\| Kamizaki, Ryo\| Kurozumi, Akira\| Matsushita, Toshi\| Ohno, Seiichiro\| Kanazawa, Susumu\| Asaumi, Junichi\|
抄録	Clinical research using restricted diffusion-weighted imaging, especially diffusion kurtosis (DK) imaging, has been progressing, with reports on its effectiveness in the diagnostic imaging of cerebral infarctions, neurodegenerative diseases, and tumors, among others. However, the application of DK imaging in daily clinical practice has not spread because of the long imaging time required and the use of specific software for image creation. Herein, with the aim of promoting clinical research using DK imaging at any medical facility, we evaluated fast DK imaging using a new software program. We developed a new macro program that produces DK images using general-purpose, inexpensive software (Microsoft Excel and ImageJ), and we evaluated fast DK imaging using bio-phantoms and a healthy volunteer in clinical trials. The DK images created by the new software with diffusion-weighted images captured with short-time imaging sequences were similar to the original DK images captured with long-time imaging sequences. The DK images using three b-values, which can reduce the imaging time by 43%, were equivalent to the DK images using five b-values. The DK imaging technique developed herein might allow any medical facility to increase its daily clinical use of DK imaging and easily conduct clinical research.
キーワード	fast diffusion kurtosis imaging mean kurtosis restricted diffusion Excel ImageJ
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-06
巻	76巻
号	3号
出版者	Okayama University Medical School
開始ページ	297
終了ページ	305
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35790360
Web of Science KeyUT	000823568300009

Factors Associated with Surgical Field Bacterial Detection during Total Hip Arthroplasty

JaLCDOI	10.18926/AMO/63738
フルテキストURL	76_3_291.pdf
著者	Miyake, Yoshiaki\| Mitani, Shigeru\| Namba, Yoshifumi\| Umehara, Norifumi\| Kawamoto, Toyohiro\| Furuichi, Shuro\|
抄録	Total hip arthroplasty (THA) provides relief from hip pain and improves hip function. However, periprosthetic joint infection (PJI) remains an area of concern. We examined the detection rate of bacteria from surgical fields in wound closure, along with the relationship between bacterial detection rate and type of antiseptic, surgery time, and surgeon experience for 500 patients who underwent THA at our department. The mean age at surgery was 64.3 (± 27.3) years. The bacterial detection rate was 4.6%. None of the cases revealed PJI. No significant association between the detection rate and type of antiseptic used or surgery time was observed. However, for patients treated by surgeons with < 10 years of orthopedic experience, a detection rate of 7.3% was found, while a rate of 1.3% was observed for those treated by surgeons with ≥ 10 years of orthopedic experience. This finding indicated that orthopedic experience of less than 10 years was significantly associated with an increased bacterial detection rate (chi-square test, p=0.002). The detection rate was associated with surgeon experience but not with antiseptic type or surgery time. It is possible that intraoperative handling may increase the number of bacteria in surgical fields in wound closure.
キーワード	total hip arthroplasty bacterial contamination periprosthetic joint infection
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-06
巻	76巻
号	3号
出版者	Okayama University Medical School
開始ページ	291
終了ページ	295
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35790359
Web of Science KeyUT	000823568300008

Mid-term (30- to 90-day) neurological changes in out-of-hospital cardiac arrest patients: A nationwide retrospective study (the JAAM-OHCA registry)

フルテキストURL	fulltext20220630-9.pdf
著者	Naito, Hiromichi\| Nojima, Tsuyoshi\| Yorifuji, Takashi\| Fujisaki, Noritomo\| Nakao, Atsunori\|
キーワード	Post cardiac arrest syndrome Hypoxic ischemic brain injury Cardiopulmonary resuscitation Prognosis
発行日	2022-8
出版物タイトル	The American Journal of Emergency Medicine
巻	58巻
出版者	Elsevier BV
開始ページ	27
終了ページ	32
ISSN	0735-6757
NCID	AA10642870
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Authors.
論文のバージョン	publisher
PubMed ID	35623180
DOI	10.1016/j.ajem.2022.05.017
Web of Science KeyUT	000808614800006

Prehospital emergency life-saving technicians promote the survival of trauma patients: A retrospective cohort study

フルテキストURL	fulltext20220630-8.pdf
著者	Nishimura, Takeshi\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Ishihara, Satoshi\| Nakayama, Shinichi\| Nakao, Atsunori\|
キーワード	JTDB Prehospital Emergency life-saving technician Trauma
発行日	2022-06
出版物タイトル	The American Journal of Emergency Medicine
巻	56巻
出版者	Elsevier BV
開始ページ	218
終了ページ	222
ISSN	0735-6757
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Authors.
論文のバージョン	publisher
PubMed ID	35447563
DOI	10.1016/j.ajem.2022.04.004
Web of Science KeyUT	000799775900035
関連URL	isVersionOf https://doi.org/10.1016/j.ajem.2022.04.004

Impact of Breast Cancer Awareness Month on Public Interest in the United States between 2012 and 2021: A Google Trends Analysis

フルテキストURL	fulltext.pdf
著者	Nishimura, Yoshito\| Acoba, Jared D.\|
キーワード	Breast Cancer Awareness Month breast cancer Google Trends trend analysis
発行日	2022-05-21
出版物タイトル	Cancers
巻	14巻
号	10号
出版者	MDPI
開始ページ	2534
ISSN	2072-6694
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35626141
DOI	10.3390/cancers14102534
Web of Science KeyUT	000803386600001
関連URL	isVersionOf https://doi.org/10.3390/cancers14102534

El Ninõ and Commodity Prices: New Findings From Partial Wavelet Coherence Analysis

フルテキストURL	fulltext.pdf
著者	Cai, Xiaojing\| Sakemoto, Ryuta\|
キーワード	climate risk commodity prices partial wavelet coherence El Nino ENSO
発行日	2022-05-16
出版物タイトル	Frontiers In Environmental Science
巻	10巻
出版者	Frontiers Media SA
開始ページ	893879
ISSN	2296-665X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Cai and Sakemoto.
論文のバージョン	publisher
DOI	10.3389/fenvs.2022.893879
Web of Science KeyUT	000803025700001
関連URL	isVersionOf https://doi.org/10.3389/fenvs.2022.893879

Interest in Infectious Diseases specialty among Japanese medical students amidst the COVID-19 pandemic: A web-based, cross-sectional study

フルテキストURL	fulltext.pdf
著者	Hagiya, Hideharu\| Otsuka, Yuki\| Tokumasu, Kazuki\| Honda, Hiroyuki\| Nishimura, Yoshito\| Obika, Mikako\| Otsuka, Fumio\|
発行日	2022-04-21
出版物タイトル	PLOS ONE
巻	17巻
号	4号
出版者	Public Library Science
開始ページ	e0267587
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Hagiya et al.
論文のバージョン	publisher
PubMed ID	35446911
DOI	10.1371/journal.pone.0267587
Web of Science KeyUT	000795468200022
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0267587

Can Blood Ammonia Level, Prehospital Time, and Return of Spontaneous Circulation Predict Neurological Outcomes of Out-of-Hospital Cardiac Arrest Patients? A Nationwide, Retrospective Cohort Study

フルテキストURL	fulltext.pdf
著者	Nojima, Tsuyoshi\| Naito, Hiromichi\| Obara, Takafumi\| Ageta, Kohei\| Yakushiji, Hiromasa\| Yumoto, Tetsuya\| Fujisaki, Noritomo\| Nakao, Atsunori\|
キーワード	ammonia cardiopulmonary resuscitation neurological outcome biomarkers
発行日	2022-05-04
出版物タイトル	Journal Of Clinical Medicine
巻	11巻
号	9号
出版者	MDPI
開始ページ	2566
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35566692
DOI	10.3390/jcm11092566
Web of Science KeyUT	000794498600001
関連URL	isVersionOf https://doi.org/10.3390/jcm11092566

Cholera Outbreaks in India, 2011-2020: A Systematic Review

フルテキストURL	fulltext.pdf
著者	Muzembo, Basilua Andre\| Kitahara, Kei\| Debnath, Anusuya\| Ohno, Ayumu\| Okamoto, Keinosuke\| Miyoshi, Shin-Ichi\|
キーワード	cholera outbreak water supply open defecation sewage household food close contact behavioral changes India
発行日	2022-05-08
出版物タイトル	International Journal Of Environmental Research and Public Health
巻	19巻
号	9号
出版者	MDPI
開始ページ	5738
ISSN	1660-4601
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35565133
DOI	10.3390/ijerph19095738
Web of Science KeyUT	000794591500001
関連URL	isVersionOf https://doi.org/10.3390/ijerph19095738

Increased cleft width during knee flexion is useful for the diagnosis of medial meniscus posterior root tears

フルテキストURL	fulltext20220518-1.pdf figure20220518-1.pdf
著者	Hiranaka, Takaaki\| Furumatsu, Takayuki\| Miyazawa, Shinichi\| Kintaka, Keisuke\| Higashihara, Naohiro\| Tamura, Masanori\| Zhang, Ximing\| Xue, Haowei\| Ozaki, Toshifumi\|
キーワード	Medial meniscus Posterior root tear Magnetic resonance imaging Extrusion Cleft sign Graben sign
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00167-022-06983-8\|
発行日	2022-05-04
出版物タイトル	Knee Surgery, Sports Traumatology, Arthroscopy
巻	30巻
号	11号
出版者	Springer Science and Business Media LLC
開始ページ	3726
終了ページ	3732
ISSN	0942-2056
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2022
論文のバージョン	author
PubMed ID	35508552
DOI	10.1007/s00167-022-06983-8
Web of Science KeyUT	000790611800003
関連URL	isVersionOf https://doi.org/10.1007/s00167-022-06983-8

Pharmacokinetic analysis of new synthetic antimalarial N-251

フルテキストURL	fulltext20220511-2.pdf
著者	Okada, Kazuaki\| Sato, Akira\| Hiramoto, Akiko\| Isogawa, Rena\| Kurosaki, Yuji\| Higaki, Kazutaka\| Miyoshi, Shin-Ichi\| Chang, Kyung-Soo\| Kim, Hye-Sook\|
発行日	2019-7-5
出版物タイトル	Tropical Medicine and Health
巻	47巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	40
ISSN	1349-4147
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s).
論文のバージョン	publisher
PubMed ID	31312098
DOI	10.1186/s41182-019-0167-4
Web of Science KeyUT	000475630800001
関連URL	isVersionOf https://doi.org/10.1186/s41182-019-0167-4

Resonance modes of a metal-semiconductor-metal multilayer mediated by electric charge

フルテキストURL	fulltext.pdf
著者	Isobe, Kazuma\| Hanamura, Katsunori\|
キーワード	resonance modes finite difference time domain method metal-semiconductor-metal multilayer lumped-element model Fabry-Perot interference surface plasmon polariton electric charge
発行日	2022-04-25
出版物タイトル	Journal Of Physics Communications
巻	6巻
号	4号
出版者	IOP Publishing Ltd
開始ページ	045006
ISSN	2399-6528
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Author(s).
論文のバージョン	publisher
DOI	10.1088/2399-6528/ac678f
Web of Science KeyUT	000787039200001
関連URL	isVersionOf https://doi.org/10.1088/2399-6528/ac678f

Association between timing of speech and language therapy initiation and outcomes among post-extubation dysphagia patients: a multicenter retrospective cohort study

フルテキストURL	fulltext.pdf
著者	Hongo, Takashi\| Yamamoto, Ryohei\| Liu, Keibun\| Yaguchi, Takahiko\| Dote, Hisashi\| Saito, Ryusuke\| Masuyama, Tomoyuki\| Nakatsuka, Kosuke\| Watanabe, Shinichi\| Kanaya, Takahiro\| Yamaguchi, Tomoya\| Yumoto, Tetsuya\| Naito, Hiromichi\| Nakao, Atsunori\|
キーワード	Post-extubation dysphagia Speech and language therapy Intensive care Dysphagia Aspiration pneumonia
発行日	2022-04-08
出版物タイトル	Critical Care
巻	26巻
号	1号
出版者	BMC
開始ページ	98
ISSN	1364-8535
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	35395802
DOI	10.1186/s13054-022-03974-6
Web of Science KeyUT	000779598400004
関連URL	isVersionOf https://doi.org/10.1186/s13054-022-03974-6

Retrospective Cohort Study of Clinical Efficacy and Safety of Cefozopran for Treating Febrile Neutropenia during Chemotherapy in Patients with Lung Cancer

JaLCDOI	10.18926/AMO/63410
フルテキストURL	76_2_167.pdf
著者	Higashionna, Tsukasa\| Ushio, Soichiro\| Esumi, Satoru\| Murakawa, Kiminaka\| Kitamura, Yoshihisa\| Sendo, Toshiaki\|
抄録	Febrile neutropenia (FN) is a serious side effect in patients undergoing cancer chemotherapy and frequently proves fatal. Since infection control is crucial in the management of FN, the antimicrobial agent cefozopran (CZOP) has been recommended but not approved for routine use in clinical care of FN in Japan. However, few studies of CZOP in the management of FN have used a thrice daily dose schedule. The aim of this study was to retrospectively compare the efficacy and safety of CZOP at a dose of 1 g three times daily to those of cefepime (CFPM) in the treatment of FN in our lung cancer patients. The response rates of the CZOP and CFPM groups were 89.5% (17/19 cases) and 83.0% (39/47 cases), respectively, with no significant difference between the two groups. The median duration of antimicrobial treatment was 6 days (4-10 days) in the CZOP group and 7 days (3-13 days) in the CFPM group, with no significant difference between groups. The incidence rates of adverse events were 21.1% (4/19 cases) in the CZOP group and 19.1% (9/47 cases) in the CFPM group. No adverse events of Grade 3 or higher were observed in either group. The findings of the present study suggest that CZOP administration at a dose of 1 g three times per day as an antimicrobial treatment alternative against FN.
キーワード	febrile neutropenia cefozopran cefepime lung cancer retrospective
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	167
終了ページ	172
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503444
Web of Science KeyUT	000792374900008

Changes in Plasma Clozapine Levels after Smoking Cessation in Japanese Inpatients with Schizophrenia: A Retrospective Cohort Study

JaLCDOI	10.18926/AMO/63407
フルテキストURL	76_2_137.pdf
著者	Tsukahara, Masaru\| So, Ryuhei\| Yada, Yuji\| Kodama, Masafumi\| Kishi, Yoshiki\| Yamada, Norihito\|
抄録	Although reported for Caucasians, changes in plasma clozapine levels after smoking cessation in East Asians remain unclear. We here investigated plasma clozapine levels before and after smoking cessation in Japanese inpatients with schizophrenia. We conducted a retrospective chart review of 14 inpatients with schizophrenia who were being treated with clozapine between June 1, 2019, and July 31, 2019 and who were smokers as of July 1, 2019, the day on which a smoking ban was instituted in the tertiary public psychiatric hospital. The primary outcome was individual differences in plasma clozapine levels between before and after the smoking ban, which were compared using paired t-tests. The mean plasma clozapine level was significantly increased, by 213.4 ng/mL (95% CI 119.9-306.8; p<0.01) or 53.2%. Four of the 14 inpatients experienced clinically significant side effects, such as myoclonus, drooling, and amnesia, due to the development of high plasma clozapine levels. Our findings indicated that close monitoring of plasma clozapine levels before and after smoking cessation and prior dose adjustment of clozapine may be necessary, to prevent a significant risk of developing high plasma clozapine levels, even in Japanese patients.
キーワード	Asian clozapine schizophrenia smoking
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	137
終了ページ	143
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503441
Web of Science KeyUT	000792374900005

Grade of Subchondral Insufficiency Fracture of the Knee and the Presence of a Posterior Shiny-Corner Lesion are Correlated with Duration of Medial Meniscus Posterior Root Tear in Women

JaLCDOI	10.18926/AMO/63405
フルテキストURL	76_2_121.pdf
著者	Okazaki, Yuki\| Furumatsu, Takayuki\| Hiranaka, Takaaki\| Kamatsuki, Yusuke\| Nakata, Eiji\| Tetsunaga, Tomonori\| Yamane, Kentaro\| Ozaki, Toshifumi\|
抄録	Bone marrow edema (BME) after meniscus injury and risk factors for subchondral insufficiency fracture of the knee (SIFK) have been reported. However, their association with medial meniscus posterior root tear (MMPRT) remains unknown. We investigated the association of BME volume (BME-V), posterior shinycorner lesion (PSCL), and SIFK with MMPRT to examine the correlations between BME-V and medial meniscus extrusion (MME), PSCL and duration from injury to the time of magnetic resonance imaging (duration), and SIFK and duration. Twenty-nine patients who underwent surgery for MMPRT were included (mean age, 59.2; range, 39-84). The presence of PSCL, femoral BME-V (cm3), and SIFK grade (1-4) were evaluated. Preoperative factors, such as MME (mm) and duration (weeks), were investigated using multivariate linear/ logistic regression analyses. Multivariate linear regression analysis revealed duration as a significant factor for high-grade SIFK (p<0.01). Multivariate logistic regression analysis revealed duration as a significant factor for the presence of PSCL (odds ratio=0.94, p<0.05). A long duration of MMPRT leads to severe MME and highgrade SIFK (3 and 4), often resulting in knee arthroplasty. Early diagnosis of MMPRT and pullout repair can prevent severe MME and high-grade SIFK.
キーワード	medial meniscus posterior root tear subchondral insufficiency fracture bone marrow edema meniscus extrusion
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	121
終了ページ	127
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503439
Web of Science KeyUT	000792374900003