検索結果 - 岡山大学学術成果リポジトリ

Efficient DNA Fingerprinting Based on the Targeted Sequencing of Active Retrotransposon Insertion Sites Using a Bench-Top High-Throughput Sequencing Platform

著者	Monden, Yuki\| Yamamoto, Ayaka\| Shindo, Akiko\| Tahara, Makoto\|
発行日	2014-06-16
出版物タイトル	DNA Research
資料タイプ	学術雑誌論文

A rapid and enhanced DNA detection method for crop cultivar discrimination

著者	Monden, Yuki\| Takasaki, Kazuto\| Futo, Satoshi\| Niwa, Kousuke\| Kawase, Mitsuo\| Akitake, Hiroto\| Tahara, Makoto\|
発行日	2014-09-20
出版物タイトル	Journal of Biotechnology
巻	185巻
資料タイプ	学術雑誌論文

Assessment of health-related quality of life and how it predicts the outcome of pegylated interferon and ribavirin therapy for chronic hepatitis C

著者	Matsushita, Hiroshi\| Ikeda, Fusao\| Iwasaki, Yoshiaki\| Seki, Hiroyuki\| Nanba, Shintaro\| Takeuchi, Yasuto\| Moritou, Yuki\| Yasunaka, Tetsuya\| Onishi, Hideki\| Miyake, Yasuhiro\| Takaki, Akinobu\| Nouso, Kazuhiro\| Yamamoto, Kazuhide\|
発行日	2014-02
出版物タイトル	Journal of Gastroenterology and Hepatology
巻	29巻
号	2号
資料タイプ	学術雑誌論文

Impact of Chronic Kidney Disease on Left Main Coronary Artery Disease and Prognosis in Japanese Patients

著者	Dan, Kazuhiro\| Miyoshi, Toru\| Ueeda, Masayuki\| Ohtsuka, Hiroaki\| Ugawa, Satoko\| Ohnishi, Nobuhiko\| Takaishi, Atsushi\| Nakamura, Kazufumi\| Kusano, Kengo\| Ito, Hiroshi\|
発行日	2012-09
出版物タイトル	Circulation Journal
巻	76巻
号	9号
資料タイプ	学術雑誌論文

Type D Personality Is Associated with Psychological Distress and Poor Self-Rated Health among the Elderly: A Population-Based Study in Japan

著者	Kasai, Yosuke\| Suzuki, Etsuji\| Iwase, Toshihide\| Doi, Hiroyuki\| Takao, Soshi\|
発行日	2013-10-17
出版物タイトル	PLoS ONE
巻	8巻
号	10号
資料タイプ	学術雑誌論文

Long-term effect of cinacalcet hydrochloride on abdominal aortic calcification in patients on hemodialysis with secondary hyperparathyroidism

著者	Nakayama, Kazunori\| Nakao, Kazushi\| Takatori, Yuji\| Inoue, Junko\| Kojo, Shoichirou\| Akagi, Shigeru\| Fukushima, Masaki\| Wada, Jun\| Makino, Hirofumi\|
発行日	2013-12-18
出版物タイトル	International Journal of Nephrology and Renovascular Disease
巻	7巻
資料タイプ	学術雑誌論文

Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells

著者	Terasaka, Tomohiro\| Otsuka, Fumio\| Tsukamoto, Naoko\| Nakamura, Eri\| Inagaki, Kenichi\| Toma, Kishio\| Ogura-Ochi, Kanako\| Glidewell-Kenney, Christine\| Lawson, Mark A.\| Makino, Hirofumi\|
発行日	2013-12-05
出版物タイトル	Molecular and Cellular Endocrinology
巻	381巻
号	1-2号
資料タイプ	学術雑誌論文

Impaired response of hypoxic sensor protein HIF-1 alpha and its downstream proteins in the spinal motor neurons of ALS model mice

著者	Sato, Kota\| Morimoto, Nobutoshi\| Kurata, Tomoko\| Mimoto, Takafumi\| Miyazaki, Kazunori\| Ikeda, Yoshio\| Abe, Koji\|
発行日	2012-09-14
出版物タイトル	Brain Research
巻	1473巻
資料タイプ	学術雑誌論文

Reducing Hemorrhagic Complication by Dabigatran Via Neurovascular Protection After Recanalization With Tissue Plasminogen Activator in Ischemic Stroke of Rat

著者	Kono, Syoichiro\| Deguchi, Kentaro\| Omote, Yoshio\| Yunoki, Taijun\| Yamashita, Toru\| Kurata, Tomoko\| Ikeda, Yoshio\| Abe, Koji\|
発行日	2014-01
出版物タイトル	Journal of Neuroscience Research
巻	92巻
号	1号
資料タイプ	学術雑誌論文

Clinical and Pathological Improvement in Stroke-Prone Spontaneous Hypertensive Rats Related to the Pleiotropic Effect of Cilostazol

著者	Omote, Yoshio\| Deguchi, Kentaro\| Tian, FengFeng\| Kawai, Hiromi\| Kurata, Tomoko\| Yamashita, Toru\| Ohta, Yasuyuki\| Abe, Koji\|
発行日	2012-06
出版物タイトル	Stroke
巻	43巻
号	6号
資料タイプ	学術雑誌論文

Therapy for hyperthermia-induced seizures in Scn1a mutant rats

著者	Hayashi, Keiichiro\| Ueshima, Satoshi\| Ouchida, Mamoru\| Mashimo, Tomoji\| Nishiki, Teiichi\| Sendo, Toshiaki\| Serikawa, Tadao\| Matsui, Hideki\| Ohmori, Iori\|
発行日	2011-05
出版物タイトル	Epilepsia
巻	52巻
号	5号
資料タイプ	学術雑誌論文

Quantitation and Human Monocyte Cytotoxicity of the Polymerization Agent 1-Hydroxycyclohexyl Phenyl Ketone (Irgacure 184) from Three Brands of Aqueous Injection Solution

著者	Yamaji, Kazuhiko\| Kawasaki, Yoichi\| Yoshitome, Kei\| Matsunaga, Hisashi\| Sendo, Toshiaki\|
発行日	2012-10
出版物タイトル	Biological & Pharmaceutical Bulletin
巻	35巻
号	10号
資料タイプ	学術雑誌論文

The Incidence and Prognostic Value of Hypochloremia in Critically Ill Patients

著者	Tani, Makiko\| Morimatsu, Hiroshi\| Takatsu, Fumiaki\| Morita, Kiyoshi\|
発行日	2012
出版物タイトル	The Scientific World Journal
巻	2012巻
資料タイプ	学術雑誌論文

The Neutral Self-Assembling Peptide Hydrogel SPG-178 as a Topical Hemostatic Agent

著者	Komatsu, Seiji\| Nagai, Yusuke\| Naruse, Keiji\| Kimata, Yoshihiro\|
発行日	2014-07-21
出版物タイトル	PLoS ONE
巻	9巻
号	7号
資料タイプ	学術雑誌論文

Unilateral lung transplantation using right and left upper lobes: An experimental study

著者	Nishikawa, Hitoshi\| Oto, Takahiro\| Otani, Shinji\| Harada, Masaaki\| Iga, Norichika\| Miyoshi, Kentaroh\| Miyoshi, Shinichiro\|
発行日	2013-12
出版物タイトル	The Journal of Thoracic and Cardiovascular Surgery
巻	146巻
号	6号
資料タイプ	学術雑誌論文

Expression analysis of microRNAs in murine cochlear explants

著者	Hirai, Misato\| Maeda, Yukihide\| Fukushima, Kunihiro\| Sugaya, Akiko\| Kataoka, Yuko\| Nishizaki, Kazunori\|
発行日	2011-09-14
出版物タイトル	NeuroReport
巻	22巻
号	13号
資料タイプ	学術雑誌論文

For Vol.68, No.3 pp157-162 Usefulness of High Mobility Group Box 1 Protein as a Plasma Biomarker in Patient with Peripheral Artery Disease

JaLCDOI	10.18926/AMO/52792
フルテキストURL	68_4_253.pdf
著者	Oozawa, Susumu\| Sano, Shunji\| Nishibori, Masahiro\|
抄録	Atherosclerosis is often associated with chronic vascular inflammation. High-mobility group box 1 protein (HMGB1) plays various roles, not only as a transcriptional regulatory factor in the nucleus, but also as an inflammatory mediator. A previous study suggested that fibrinogen is an important factor associated with atherosclerosis progression. The present study was performed to examine the levels of plasma HMGB1 protein in atherosclerosis patients. We studied 24 patients with peripheral artery disease (PAD) with atherosclerosis, and 10 healthy controls. We found that the concentrations of HMGB1 were increased in the plasma of the patients with atherosclerosis, and there were significant correlations between the plasma HMGB1 and fibrinogen levels. Plasma HMGB1 may play a key role in the pathogenesis of clinical and experimental atherosclerosis.
キーワード	HMGB1 fibrinogen atherosclerosis peripheral artery disease
Amo Type	Erratum
出版物タイトル	Acta Medica Okayama
発行日	2014-08
巻	68巻
号	4号
出版者	Okayama University Medical School
開始ページ	253
終了ページ	253
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
Web of Science KeyUT	000340687500008
関連URL	http://doi.org/10.18926/AMO/52656

Prevalence and Outcomes of Acute Hepatitis B in Okayama, Japan, 2006-2010

JaLCDOI	10.18926/AMO/52790
フルテキストURL	68_4_243.pdf
著者	Wada, Nozomu\| Yasunaka, Tetsuya\| Ikeda, Fusao\| Nishina, Sohji\| Korenaga, Masaaki\| Hino, Keisuke\| Fujioka, Shin-ichi\| Osawa, Toshiya\| Itoshima, Tatsuya\| Kawanaka, Miwa\| Yamada, Gotaro\| Kariyama, Kazuya\| Takayama, Hiroki\| Kubota, Junichi\| Morimoto, Yoichi\| Mizushima, Takaaki\| Yamashita, Haruhiko\| Tanioka, Hiroaki\| Negoro, Yuji\| Toshimori, Junichi\| Kobashi, Haruhiko\| Hirano, Atsushi\| Itano, Yasuo\| Takaki, Akinobu\| Yamamoto, Kazuhide\|
抄録	Hepatitis B virus (HBV) is one of the major viruses causing acute hepatitis. Recently, the incidence of acute hepatitis with genotype A has been increasing in Japan. The aim of this study was to investigate acute hepatitis B (AHB) in Okayama prefecture, with special attention to HBV genotype A. AHB patients who visited one of 12 general hospitals in Okayama prefecture between 2006 and 2010 were retrospectively analyzed. Over the course of the study period, 128 patients were diagnosed with AHB. Sexual transmission was supposed in the majority of patients (78 patients, 61%), including 59 (76%) having sex with heterosexual partners. The genotypes of HBV were assessed in 90 patients (70%), of whom 27 patients were infected with genotype A, 5 with genotype B, and 58 with genotype C. The prevalence of genotype A was significantly higher among male patients (28.7%), aged 20-29 (35.6%, p＜0.01), among men who had sex with men (100%, p＜0.005), and among patients having sex with unspecified partners (44.8%, p＜0.005). Genotype A was not a significant factor associated with delayed HBsAg disappearance. Caution should be exercised with regard to sexually transmissible diseases in order to slow the pandemic spread of AHB due to genotype A.
キーワード	acute hepatitis hepatitis B virus
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2014-08
巻	68巻
号	4号
出版者	Okayama University Medical School
開始ページ	243
終了ページ	247
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25145410
Web of Science KeyUT	000340687500006

Factors Associated with Remission and/or Regression of Microalbuminuria in Type 2 Diabetes Mellitus

JaLCDOI	10.18926/AMO/52789
フルテキストURL	68_4_235.pdf
著者	Ono, Tetsuichiro\| Shikata, Kenichi\| Obika, Mikako\| Miyatake, Nobuyuki\| Kodera, Ryo\| Hirota, Daisyo\| Wada, Jun\| Kataoka, Hitomi\| Ogawa, Daisuke\| Makino, Hirofumi\|
抄録	The aim of this study was to clarify the factors associated with the remission and/or regression of microalbuminuria in Japanese patients with type 2 diabetes mellitus. We retrospectively analyzed the data of 130 patients with type 2 diabetes mellitus with microalbuminuria for 2-6 years (3.39±1.31 years). Remission was defined as improving from microalbuminuria to normoalbuminuria using the albumin/creatinine ratio (ACR), and regression of microalbuminuria was defined as a decrease in ACR of 50% or more from baseline. Progression of microalbuminuria was defined as progressing from microalbuminuria to overt proteinuria during the follow-up period. Among 130 patients with type 2 diabetes mellitus with microalbuminuria, 57 and 13 patients were defined as having remission and regression, respectively, while 26 patients progressed to overt proteinuria. Sex (female), higher HDL cholesterol and lower HbA1c were determinant factors associated with remission/regression of microalbuminuria by logistic regression analysis. Lower systolic blood pressure (SBP) was also correlated with remission/regression, but not at a significant level. These results suggest that proper control of blood glucose, BP and lipid profiles may be associated with remission and/or regression of type 2 diabetes mellitus with microalbuminuria in clinical practice.
キーワード	microalbuminuria type 2 diabetes mellitus remission regression
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2014-08
巻	68巻
号	4号
出版者	Okayama University Medical School
開始ページ	235
終了ページ	241
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25145409
Web of Science KeyUT	000340687500005
関連URL	http://ousar.lib.okayama-u.ac.jp/metadata/52828

Renal Distribution of Vasohibin-1 in Patients with Chronic Kidney Disease

JaLCDOI	10.18926/AMO/52788
フルテキストURL	68_4_219.pdf
著者	Hinamoto, Norikazu\| Maeshima, Yohei\| Saito, Daisuke\| Yamasaki, Hiroko\| Tanabe, Katsuyuki\| Nasu, Tatsuyo\| Watatani, Hiroyuki\| Ujike, Haruyo\| Kinomura, Masaru\| Sugiyama, Hitoshi\| Sonoda, Hikaru\| Kanomata, Naoki\| Sato, Yasufumi\| Makino, Hirofumi\|
抄録	Experimental studies have demonstrated the involvement of angiogenesis-related factors in the progression of chronic kidney disease (CKD). There have so far been no reports investigating the distribution and clinical roles of Vasohibin-1 (VASH-1), a negative feedback regulator of angiogenesis, in CKD. We recruited 54 Japanese CKD patients and 6 patients who had normal renal tissues excised due to localized renal cell carcinoma. We evaluated the correlations between the renal expression level of VASH-1 and the clinical/histological parameters. VASH-1 was observed in renal endothelial/mesangial cells, crescentic lesions and interstitial inflammatory cells. Significant positive correlations were observed between 1) crescent formation and the number of VASH-1+ cells in the glomerulus (r＝0.48, p＝0.001) or cortex (r＝0.64, p＜0.0001), 2) interstitial cell infiltration and the number of VASH-1+ cells in the cortex (r＝0.34, p＝0.02), 3) the glomerular VEGFR-2+ area and the number of VASH-1+ cells in the glomerulus (r＝0.44, p＝0.01) or medulla (r＝0.63, p＝0.01). These results suggest that the renal levels of VASH-1 may be affected by local inflammation, crescentic lesions and VEGFR-2.
キーワード	chronic kidney disease inflammation Vasohibin-1 VEGF-A VEGFR-2
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2014-08
巻	68巻
号	4号
出版者	Okayama University Medical School
開始ページ	219
終了ページ	233
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25145408
Web of Science KeyUT	000340687500004
関連URL	http://ousar.lib.okayama-u.ac.jp/metadata/52824