result 127 件
Author | Oguni, Kohei| Fukushima, Shinnosuke| Hagiya, Hideharu| Kato, Atsushi| Suyama, Atsuhito| Iwata, Takehiro| Miyawaki, Yoshia| Ono, Sawako| Iio, Koji| Otsuka, Fumio| |
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Keywords | Cryptococcosis Fluconazole Glucocorticoids Prostatitis Tocilizumab |
Note | © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2026.| |
Published Date | 2025-01 |
Publication Title | Journal of Infection and Chemotherapy |
Volume | volume31 |
Issue | issue1 |
Publisher | Elsevier |
Start Page | 102494 |
ISSN | 1341-321X |
NCID | AA11057978 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. |
File Version | author |
PubMed ID | 39152054 |
DOI | 10.1016/j.jiac.2024.08.009 |
Web of Science KeyUT | 001419817400001 |
Related Url | isVersionOf https://doi.org/10.1016/j.jiac.2024.08.009 |
JaLCDOI | 10.18926/AMO/67873 |
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FullText URL | 78_6_465.pdf |
Author | Ocho, Kazuki| Hagiya, Hideharu| Ishikawa, Hisashi| Otsuka, Fumio| |
Abstract | An 81-year-old Japanese man with a medical history of diabetes mellitus and hypertension was diagnosed with the novel coronavirus disease 2019 (COVID-19). The patient developed pain in the bilateral shoulders and hips 3 days after the disease onset and presented to our outpatient clinic after 1 month. Referring to diagnostic criteria, we diagnosed him with polymyalgia rheumatica (PMR). We initiated prednisolone at 15 mg per day and his symptoms improved immediately. The clinical course of the patient indicated that the SARS-CoV-2 infection triggered the onset of autoimmune disease, PMR in this case. |
Keywords | COVID-19 SARS-CoV-2 polymyalgia rheumatica autoimmune diseases human leukocyte antigen |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-12 |
Volume | volume78 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 465 |
End Page | 468 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39719320 |
Web of Science KeyUT | 001397269500002 |
FullText URL | K0007099_abstract_review.pdf K0007099_summary.pdf |
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Author | FUJITA, Koji| |
Published Date | 2024-09-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7099号 |
Granted Date | 2024-09-25 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. |
JaLCDOI | 10.18926/AMO/67664 |
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FullText URL | 78_5_401.pdf |
Author | Toyota, Yusuke| Uda, Kazuhiro| Shirabe, Komei| Moriwake, Tadashi| |
Abstract | Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas. |
Keywords | child tick-borne disease severe febrile thrombocytopenia syndrome zoonoses |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-10 |
Volume | volume78 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 401 |
End Page | 405 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39467658 |
JaLCDOI | 10.18926/AMO/67657 |
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FullText URL | 78_5_371.pdf |
Author | Gotoh, Kazuyoshi| Miyoshi, Makoto| I Putu Bayu Mayura| Tsuji, Shuma| Iio, Koji| Fukushima, Shinnosuke| Matsushita, Osamu| Hagiya, Hideharu| |
Abstract | Spread of carbapenemase-producing Enterobacterales (CPE) is an ongoing public health issue worldwide, including in Japan. In this study, we investigated the phenotypic and genetic characteristics of CPE isolates at Okayama University Hospital over the 5 years (2013-2018) prior to the outbreak of the 2019 coronavirus pandemic. Of 24 carbapenem-resistant Enterobacterales isolated during the study period, we identified 8 CPE isolates harboring blaIMP-1 (5 isolates) and blaIMP-6 genes (3 isolates). Bacterial species and carbapenem susceptibility patterns exhibited diversity. Minimum inhibitory concentrations (MICs) of meropenem were generally higher than those of imipenem and biapenem. Results of pulsed-field gel electrophoresis demonstrated that neither clonal nor plasmid-mediated outbreaks of blaIMP-harboring CPE isolates have developed at our hospital. One Klebsiella oxytoca isolate showed a high MIC (128 μg/mL) of meropenem, which could be explained by the high plasmid copy number. Subsequent analysis of this isolate may elucidate the intricacies of carbapenem resistance profiles among CPE isolates. Collectively, our findings underscore the necessity for ongoing genetic surveillance of CPE, complemented by tailored approaches for infection prevention and control. |
Keywords | antimicrobial resistance carbapenemase-producing enterobacterales carbapenemase-resistant enterobacterales Silent pandemic whole genome sequence |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-10 |
Volume | volume78 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 371 |
End Page | 376 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39467655 |
Web of Science KeyUT | 001343346400003 |
JaLCDOI | 10.18926/AMO/67656 |
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FullText URL | 78_5_363.pdf |
Author | Takanaga, Satoe| Matsumoto, Naomi| Kadowaki, Tomoka| Takao, Soshi| Yorifuji, Takashi| |
Abstract | Kawasaki disease (KD) is a pediatric disease of unknown etiology that commonly affects infants in East Asia. Infants born small for gestational age (SGA) have weaker immune systems and are more susceptible to infection. Using data from a nationwide Japanese birth cohort study conducted in 2010 (n=34,579), we investigated whether SGA increases the risk of KD. SGA was defined as birth weight below the 10th percentile for gestational age. The outcome was hospitalization for KD between 6 and 30 months of age. The association between SGA and hospitalization for KD, adjusted for child and maternal factors, was examined using logistic regression. Of the 231 children hospitalized for KD, 9.5% were SGA. Further statistical analysis showed that SGA did not increase the odds ratio (OR) of hospitalization for KD (adjusted OR 1.12, 95% confidence interval 0.71-1.75). This result was not changed with stratification by early daycare attendance and preterm status. Reasons for the lack of association may include the multifactorial pathogenesis of KD; in addition, the types of infections to which SGA infants are predisposed may differ from those triggering KD. Overall, our large nationwide study found no association between SGA and KD. |
Keywords | Kawasaki disease (KD) small for gestational age (SGA) cohort epidemiology |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-10 |
Volume | volume78 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 363 |
End Page | 370 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 39467654 |
JaLCDOI | 10.18926/AMO/67199 |
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FullText URL | 78_3_245.pdf |
Author | Akagawa, Manabu| Saito, Hidetomo| Takahashi, Yasuhiro| Iwamoto, Yosuke| Iida, Junpei| Yoshikawa, Takayuki| Abe, Toshiki| Saito, Kimio| Kijima, Hiroaki| Kasukawa, Yuji| Hongo, Michio| Miyakoshi, Naohisa| |
Abstract | Although several studies have suggested a possible association between sarcopenia and knee osteoarthritis (OA) in the elderly, there remains no definitive evidence. Recently, however, the serum creatinine/cystatin C ratio (sarcopenia index: SI) was reported to correlate with skeletal muscle mass. The present retrospective study therefore investigated the impact of reduced skeletal muscle mass on advanced knee OA using SI. In 55 individuals scheduled for knee osteotomy or knee arthroplasty, correlations between SI and patient-reported outcomes such as the Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Oxford Knee Score (OKS) were explored. Significant associations were found between SI and the KSS functional activity score (β=0.37; p=0.022), KOOS subscale for activities of daily living (β=0.42; p=0.0096), and OKS (β=0.42; p=0.0095). This study underscores the role of reduced muscle mass in functional outcomes and introduces SI as a valuable marker for assessing muscle loss in knee OA patients. |
Keywords | knee osteoarthritis sarcopenia index reduced muscle mass activities of daily living functional activity |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-06 |
Volume | volume78 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 245 |
End Page | 250 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38902212 |
Web of Science KeyUT | 001267351000005 |
JaLCDOI | 10.18926/AMO/67195 |
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FullText URL | 78_3_205.pdf |
Author | Hagiya, Hideharu| |
Abstract | The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists. |
Keywords | antimicrobial resistance emerging infectious diseases infection prevention and control medical education silent pandemic |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2024-06 |
Volume | volume78 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 205 |
End Page | 213 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38902208 |
Web of Science KeyUT | 001267351000001 |
JaLCDOI | 10.18926/AMO/66928 |
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FullText URL | 78_2_193.pdf |
Author | Kashima, Hajime| Teraishi, Fuminori| Matsumi, Yuki| Shimamura, Hiroshi| Fujiwara, Toshiyoshi| |
Abstract | Tailgut cyst is a rare cystic disease of the anterior sacral surface and the remains of an embryonic tail gut. Tailgut cysts have a potential for malignancy, and complete resection with an adequate surgical margin is necessary. Even if incomplete resection does not result in recurrence of malignant disease, there is a risk of local infection leading to refractory fistulas. The optimal treatment for such refractory recurrent lesions has not been reported. We describe a case in which the combination of laparoscopic and transsacral approaches was effective for resecting a recurrent refractory fistula after incomplete resection of a tail gut cyst. |
Keywords | tailgut cyst laparoscopic resection fistula formation |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 193 |
End Page | 196 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688837 |
Web of Science KeyUT | 001227932200003 |
JaLCDOI | 10.18926/AMO/66927 |
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FullText URL | 78_2_185.pdf |
Author | Takahashi, Hiroko| Eguchi, Jun| Watanabe, Mayu| Nakayama, Masanori| Wada, Jun| |
Abstract | The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients. |
Keywords | obesity type 2 diabetes COVID-19 vaccination |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 185 |
End Page | 191 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688836 |
Web of Science KeyUT | 001227932200002 |
JaLCDOI | 10.18926/AMO/66913 |
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FullText URL | 78_2_107.pdf |
Author | Han, Dongxiang| Du, Jianxiu| Wang, Wei| Wang, Cui| |
Abstract | Vertical transmission of hepatitis B virus (HBV), especially in Asia, is a key target in the global elimination of HBV. This study assessed the effects of tenofovir disoproxil fumarate (TDF) in pregnant women for mother-to-infant transmission of HBV. A total of 122 pregnant women at our hospital met the inclusion criteria for high HBV DNA viral loads. They were randomly divided into TDF-treatment (n=70) and placebo (n=52) groups. Maternal liver function and serum HBV DNA load were tested before and after treatment. Clinical and laboratory data of infants were assayed at delivery and 7-months post-partum visit and compared between the two groups. There was no difference in clinical characteristics of participants between the two groups. There were no significant differences in liver function markers, including alanine aminotransferase, total bilirubin, blood creatinine, and blood urea nitrogen levels before and after TDF treatment. The serum HBV DNA viral load of the TDF-treated group became significantly lower than those of the control group and their own pre-medication levels. Infants showed no significant difference in body growth, including weight, height, head size, and five-min Apgar score. At 7 months after birth, 94.29% of infants in the TDF group and 86.54% of control-group infants had protective HBsAb levels ≥ 10 mIU/ml (p>0.05). The HBV infection rate of infants in the TDF-treated group was lower than that in the non-treated group. In high-HBV-DNA-load pregnant women, TDF administered from 28 weeks gestational age to delivery was associated with a lower risk of mother-to-infant transmission of HBV. |
Keywords | mother-to-infant transmission tenofovir disoproxil fumarate hepatitis B virus |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 107 |
End Page | 113 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688828 |
Web of Science KeyUT | 001229151800002 |
JaLCDOI | 10.18926/AMO/66912 |
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FullText URL | 78_2_095.pdf |
Author | Itano, Junko| Kiura, Katsuyuki| Maeda, Yoshinobu| Miyahara, Nobuaki| |
Abstract | The lungs are very complex organs, and the respiratory system performs the dual roles of repairing tissue while protecting against infection from various environmental stimuli. Persistent external irritation disrupts the immune responses of tissues and cells in the respiratory system, ultimately leading to respiratory disease. Neuropeptide Y (NPY) is a 36-amino-acid polypeptide and a neurotransmitter that regulates homeostasis. The NPY receptor is a seven-transmembrane-domain G-protein-coupled receptor with six subtypes (Y1, Y2, Y3, Y4, Y5, and Y6). Of these receptors, Y1, Y2, Y4, and Y5 are functional in humans, and Y1 plays important roles in the immune responses of many organs, including the respiratory system. NPY and the Y1 receptor have critical roles in the pathogenesis of asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. The effects of NPY on the airway immune response and pathogenesis differ among respiratory diseases. This review focuses on the involvement of NPY in the airway immune response and pathogenesis of various respiratory diseases. |
Keywords | neuropeptide y Y1 receptor airway immune response bronchial epithelial cells respiratory disease |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 95 |
End Page | 106 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688827 |
Web of Science KeyUT | 001229151800001 |
FullText URL | fulltext.pdf |
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Author | Yasutake, Nobuko| Yamamoto, Hidetaka| Kuga, Ryosuke| Jiromaru, Rina| Hongo, Takahiro| Katayama, Yoshihiro| Sonoda, Kenzo| Yahata, Hideaki| Kato, Kiyoko| Oda, Yoshinao| |
Keywords | endocervical adenocarcinoma human papillomavirus p16 Rb uterus |
Published Date | 2024-03-06 |
Publication Title | Histopathology |
Volume | volume84 |
Issue | issue7 |
Publisher | Wiley |
Start Page | 1178 |
End Page | 1191 |
ISSN | 0309-0167 |
NCID | AA00664436 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 The Authors. |
File Version | publisher |
PubMed ID | 38445509 |
DOI | 10.1111/his.15169 |
Web of Science KeyUT | 001179165100001 |
Related Url | isVersionOf https://doi.org/10.1111/his.15169 |
FullText URL | fulltext.pdf |
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Author | Fukushima, Shinnosuke| Hagiya, Hideharu| Honda, Hiroyuki| Ishida, Tomoharu| Shoji, Ryohei| Hasegawa, Kou| Otsuka, Fumio| |
Keywords | Bacteremia Calcium polystyrene sulfonate Escherichia coli Infective endocarditis Rectal ulcer |
Note | The version of record of this article, first published in Clinical Journal of Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12328-024-01949-4| |
Published Date | 2024-03-25 |
Publication Title | Clinical Journal of Gastroenterology |
Volume | volume17 |
Issue | issue3 |
Publisher | Springer Science and Business Media LLC |
Start Page | 472 |
End Page | 476 |
ISSN | 1865-7257 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024 |
File Version | publisher |
PubMed ID | 38528197 |
DOI | 10.1007/s12328-024-01949-4 |
Web of Science KeyUT | 001190477300001 |
Related Url | isVersionOf https://doi.org/10.1007/s12328-024-01949-4 |
FullText URL | fulltext20240322-01.pdf |
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Author | Matsuo, Toshihiko| Matsuo, Chie Nakago| Matsuo, Nobuhiko| Mori, Ayano| Murakami, Masaaki| Ito, Hiroshi| |
Keywords | pericardial effusion pericarditis periodontitis (periodontal disease) positron emission tomography Streptococcus |
Published Date | 2024-03-19 |
Publication Title | Journal of Investigative Medicine High Impact Case Reports |
Volume | volume12 |
Publisher | SAGE Publications |
ISSN | 2324-7096 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 American Federation for Medical Research. |
File Version | publisher |
PubMed ID | 38504421 |
DOI | 10.1177/23247096241239559 |
Web of Science KeyUT | 001188152000001 |
Related Url | isVersionOf https://doi.org/10.1177/23247096241239559 |
FullText URL | fulltext.pdf |
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Author | Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Ogawa, Chikako| Masuyama, Hisashi| Tabuchi, Takahiro| |
Keywords | cervical cancer screening social inequality screening hesitation internet survey |
Published Date | 2024-02-13 |
Publication Title | International Journal of General Medicine |
Volume | volume17 |
Publisher | Dove Press |
Start Page | 541 |
End Page | 551 |
ISSN | 1178-7074 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Mitoma et al. |
File Version | publisher |
PubMed ID | 38371520 |
DOI | 10.2147/IJGM.S453675 |
Web of Science KeyUT | 001162765400001 |
Related Url | isVersionOf https://doi.org/10.2147/IJGM.S453675 |
FullText URL | fulltext.pdf |
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Author | Kobayashi, Hiroki| Ouchi, Tomoki| Kitamura, Wataru| Asakura, Shoji| Yano, Tomofumi| Takeda, Hiromasa| Tokuda, Yoshiyuki| Yoshino, Tadashi| Maeda, Yoshinobu| |
Keywords | cold agglutinin disease severe acute respiratory syndrome coronavirus 2 sutimlimab |
Published Date | 2023-12-26 |
Publication Title | Journal of Clinical and Experimental Hematopathology |
Volume | volume63 |
Issue | issue4 |
Publisher | The Japanese Society for Lymphoreticular Tissue Research |
Start Page | 246 |
End Page | 250 |
ISSN | 1346-4280 |
NCID | AA11556796 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 The Japanese Society for Lymphoreticular Tissue Research |
File Version | publisher |
PubMed ID | 38148014 |
DOI | 10.3960/jslrt.23040 |
Web of Science KeyUT | 001134578000003 |
Related Url | isVersionOf https://doi.org/10.3960/jslrt.23040 |
JaLCDOI | 10.18926/AMO/66151 |
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FullText URL | 77_6_595.pdf |
Author | Bando, Takashi| Chuma, Masayuki| Hamano, Hirofumi| Niimura, Takahiro| Okada, Naoto| Kondo, Masateru| Izumi, Yuki| Ishida, Shunsuke| Yoshioka, Toshihiko| Asada, Mizuho| Zamami, Yoshito| Takechi, Kenshi| Goda, Mitsuhiro| Miyata, Koji| Yagi, Kenta| Izawa-Ishizawa, Yuki| Azuma, Momoyo| Yanagawa, Hiroaki| Tasaki, Yoshikazu| Ishizawa, Keisuke| |
Abstract | There is a growing concern about the relationship between vancomycin-associated nephrotoxicity (VAN) and concomitant use of nephrotoxins. We examined this relationship by combined retrospective analyses of two real-world databases. Initially, the FDA Adverse Event Reporting System (FAERS) was analyzed for the effects of concomitant use of one or more nephrotoxins on VAN and the types of combinations of nephrotoxins that exacerbate VAN. Next, electronic medical records (EMRs) of patients who received vancomycin (VCM) at Tokushima University Hospital between January 2006 and March 2019 were examined to confirm the FAERS analysis. An elevated reporting odds ratio (ROR) was observed with increases in the number of nephrotoxins administered (VCM + one nephrotoxin, adjusted ROR (95% confidence interval [CI]) 1.67 [1.51-1.85]; VCM + ≥2 nephrotoxins, adjusted ROR [95% CI] 1.54 [1.37-1.73]) in FAERS. EMRs analysis showed that the number of nephrotoxins was associated with higher incidences of VAN [odds ratio: 1.99; 95% CI: 1.42-2.78]. Overall, concomitant use of nephrotoxins was associated with an increased incidence of VAN, especially when at least one of those nephrotoxins was a renal hypoperfusion medication (furosemide, non-steroidal anti-inflammatory drugs, and vasopressors). The concomitant use of multiple nephrotoxins, especially including renal hypoperfusion medication, should be avoided to prevent VAN. |
Keywords | vancomycin-associated nephrotoxicity polypharmacy nephrotoxin spontaneous adverse event reporting database electronic medical records |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2023-12 |
Volume | volume77 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 595 |
End Page | 605 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38145933 |
Web of Science KeyUT | 001164631200004 |
FullText URL | fulltext20231205-01.pdf fig20231205-01.pdf suppl20231205-01.pdf |
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Author | Matsumoto, Naomi| Shimizu, Junya| Yokoyama, Yuji| Tsukahara, Hirokazu| Yorifuji, Takashi| |
Keywords | adverse reaction BNT162b2 COVID-19 vaccine young children |
Note | This is the peer reviewed version of the following article: [Matsumoto, N, Shimizu, J, Yokoyama, Y, Tsukahara, H, Yorifuji, T. Adverse reactions in young children receiving the coronavirus disease 2019 vaccine. Pediatr Int. 2023; 65:e15696. https://doi.org/10.1111/ped.15696], which has been published in final form at [https://doi.org/10.1111/ped.15696]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Nov. 2024.| |
Published Date | 2023-11-15 |
Publication Title | Pediatrics International |
Volume | volume65 |
Issue | issue1 |
Publisher | Wiley |
Start Page | e15696 |
ISSN | 1328-8067 |
NCID | AA11320483 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 Japan Pediatric Society. |
File Version | author |
PubMed ID | 37968891 |
DOI | 10.1111/ped.15696 |
Web of Science KeyUT | 001105283700001 |
Related Url | isVersionOf https://doi.org/10.1111/ped.15696 |
FullText URL | fulltext.pdf |
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Author | Nishihata, Yu| Liu, Ziang| Nishi, Tatsushi| |
Keywords | inventory management SEIR model evolutionary game theory |
Published Date | 2023-10-14 |
Publication Title | Applied Sciences |
Volume | volume13 |
Issue | issue20 |
Publisher | MDPI |
Start Page | 11308 |
ISSN | 2076-3417 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 by the authors. |
File Version | publisher |
DOI | 10.3390/app132011308 |
Web of Science KeyUT | 001090619000001 |
Related Url | isVersionOf https://doi.org/10.3390/app132011308 |