result 127 件
| JaLCDOI | 10.18926/AMO/65750 |
|---|---|
| FullText URL | 77_4_395.pdf |
| Author | Pavlovic, Marko| Babic, Dragan| Rastovic, Pejana| Arapovic, Jurica| Martinac, Marko| Jakovac, Sanja| Barbaric, Romana| |
| Abstract | We investigated the relationship between serum tumor necrosis factor-alpha (TNF-α) levels and psychopathological symptoms, clinical and socio-demographic characteristics and antipsychotic therapy in individuals with schizophrenia. TNF-α levels were measured in 90 patients with schizophrenia and 90 healthy controls matched by age, gender, smoking status, and body mass index. The Positive and Negative Syndrome Scale (PANSS) was used to assess the severity of psychopathology in patients. No significant differences in TNF-α levels were detected between the patients and controls (p=0.736). TNF-α levels were not correlated with total, positive, negative, general, or composite PANSS scores (all p>0.05). A significant negative correlation was observed between TNF-α levels and the PANSS cognitive factor (ρ=−0.222, p=0.035). A hierarchical regression analysis identified the cognitive factor as a significant predictor of the TNF-α level (beta=−0.258, t=−2.257, p=0.027). There were no significant differences in TNF-α levels among patients treated with different types of antipsychotics (p=0.596). TNF-α levels correlated positively with the age of onset (ρ=0.233, p=0.027) and negatively with illness duration (ρ=−0.247, p=0.019) and antipsychotic treatment duration (ρ=−0.256, p=0.015). These results indicate that TNF-α may be involved in cognitive impairment in schizophrenia, and would be a potential clinical-state marker in schizophrenia. |
| Keywords | tumor necrosis factor-alpha schizophrenia psychopathology immune system |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 395 |
| End Page | 405 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635140 |
| Web of Science KeyUT | 001163659800010 |
| JaLCDOI | 10.18926/AMO/65748 |
|---|---|
| FullText URL | 77_4_377.pdf |
| Author | Morimoto, Kosaku| Takeuchi, Yasuto| Takaki, Akinobu| Wada, Nozomu| Oyama, Atsushi| Adachi, Takuya| Onishi, Hideki| Shiraha, Hidenori| Okada, Hiroyuki| |
| Abstract | Liver fibrosis is an important phenomenon in non-alcoholic fatty liver disease (NAFLD) progression. Standard markers reflecting liver fibrosis, including the FIB-4 index, increase with age. This study aimed to identify fibrosis progression-related markers that are diagnostically beneficial even in aged individuals. Serum levels of pro- and anti-inflammatory cytokines were measured by multiple enzyme-linked immunosorbent assay. Two standard NAFLD or fibrosis progression-related markers — the FIB-4 index and APRI score — were analyzed along with cytokine levels to define the best approach to discriminate advanced fibrosis. Ninety-eight NAFLD patients were enrolled: 59 and 39 patients with fibrosis stages 1-2 and 3-4 respectively. In addition to the FIB-4 index and APRI score, the following factors showed significant differences between stages 1-2 and stages 3-4 in a multivariate analysis: platelet counts, IP-10, and RANTES. The fibrosis stage, FIB-4, APRI, PDGF-BB, and RANTES were related to the prognosis. In aged patients, IP-10, GM-CSF, and RANTES differed between stages 1-2 and stages 3-4. FIB-4 and APRI were beneficial for their correlation with fibrosis. However, to stratify either young or elderly advanced fibrosis patients, and to identify patients likely to have a bad outcome, RANTES was the best marker. |
| Keywords | NAFLD NASH liver fibrosis chemokine FIB-4 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 377 |
| End Page | 385 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635138 |
| Web of Science KeyUT | 001163659800009 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yasuda, Nami| Fujita, Tomoko| Fujioka, Takahiro| Tagawa, Mei| Kohira, Naoki| Torimaru, Kensho| Shiota, Sumiko| Kumagai, Takanori| Morita, Daichi| Ogawa, Wakano| Tsuchiya, Tomofusa| Kuroda, Teruo| |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-35256-8| |
| Published Date | 2023-05-31 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 8826 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37258635 |
| DOI | 10.1038/s41598-023-35256-8 |
| Web of Science KeyUT | 001001303600025 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-023-35256-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Muzembo, Basilua Andre| Kitahara, Kei| Mitra, Debmalya| Ohno, Ayumu| Khatiwada, Januka| Dutta, Shanta| Miyoshi, Shin-Ichi| |
| Keywords | Shigella vaccine Shigella sonnei Shigella flexneri Diarrhea Dysentery Shiga toxin Travel |
| Published Date | 2023-04 |
| Publication Title | Travel Medicine and Infectious Disease |
| Volume | volume52 |
| Publisher | Elsevier |
| Start Page | 102554 |
| ISSN | 1477-8939 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 36792021 |
| DOI | 10.1016/j.tmaid.2023.102554 |
| Web of Science KeyUT | 000944007500001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.tmaid.2023.102554 |
| FullText URL | fulltext20230629-01.pdf |
|---|---|
| Author | Hirai, Ryosuke| Hirai, Mami| Otsuka, Motoyuki| Mitsuhashi, Toshiharu| Shimodate, Yuichi| Mouri, Hirokazu| Matsueda, Kazuhiro| Yamamoto, Hiroshi| Mizuno, Motowo| |
| Keywords | Cancer screening Gastric cancer Helicobacter pylori Gastrointestinal endoscopy Atrophic gastritis |
| Note | The version of record of this article, first published in Journal of Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00535-023-02010-w| |
| Published Date | 2023-06-21 |
| Publication Title | Journal of Gastroenterology |
| Volume | volume58 |
| Issue | issue9 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 848 |
| End Page | 855 |
| ISSN | 0944-1174 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37340218 |
| DOI | 10.1007/s00535-023-02010-w |
| Web of Science KeyUT | 001009624700001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00535-023-02010-w |
| JaLCDOI | 10.18926/AMO/65495 |
|---|---|
| FullText URL | 77_3_301.pdf |
| Author | Kato, Takahide| Miyoshi, Seigo| Hamada, Chizuru| Sano, Yoshifumi| Nogami, Naoyuki| Yamaguchi, Osamu| Hamaguchi, Naohiko| |
| Abstract | Acute exacerbation (AE) of interstitial lung disease (ILD) is a severe complication of lung resection in lung cancer patients with ILD (LC-ILD). This study aimed to assess the predictive value of comorbidities other than ILD for postoperative AE in patients with LC-ILD. We retrospectively evaluated 68 patients with LC-ILD who had undergone lung resection. We classified them into two groups: those who had developed postoperative AE within 30 days after resection and those who had not. We analyzed patient characteristics, high-resolution computed tomography findings, clinical data, pulmonary function, and intraoperative data. The incidence of postoperative AEs was 11.8%. In univariate analysis, performance status (PS), honeycombing, forced vital capacity (FVC), and high hemoglobin A1c (HbA1c) levels without comorbidities were significantly associated with postoperative AE. Patients were divided into two groups according to cutoff levels of those four variables as determined by receiver operating characteristic curves, revealing that the rates of patients without postoperative AE differed significantly between groups. The present results suggested that preoperative comorbidities other than ILD were not risk factors for postoperative AE in patients with LC-ILD. However, a high preoperative HbA1c level, poor PS, low FVC, and honeycombing may be associated with postoperative AE of LC-ILD. |
| Keywords | lung cancer interstitial lung disease acute exacerbation comorbidity |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 301 |
| End Page | 309 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357631 |
| Web of Science KeyUT | 001026279600008 |
| JaLCDOI | 10.18926/AMO/65494 |
|---|---|
| FullText URL | 77_3_291.pdf |
| Author | Himei, Hitomi| Kato, Hironari| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Abstract | We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal. |
| Keywords | benign biliary stricture inside stent plastic stent |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357630 |
| Web of Science KeyUT | 001026279600007 |
| JaLCDOI | 10.18926/AMO/65490 |
|---|---|
| FullText URL | 77_3_255.pdf |
| Author | Fukushima, Shinnosuke| Hagiya, Hideharu| Uda, Kazuhiro| Gotoh, Kazuyoshi| Otsuka, Fumio| |
| Abstract | Antimicrobial resistance is an emerging global threat that must be addressed using a multidisciplinary approach. This study aimed to raise awareness of high-level antimicrobial-resistant (AMR) pathogens in Japan by comparing their recent prevalences among prefectures, particularly Okayama. Data for the isolation proportions of meropenem-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae, and levofloxacin-resistant E. coli and K. pneumoniae were collected from the Japan Nosocomial Infections Surveillance, a national database sponsored by the Japanese Ministry of Health, Labour, and Welfare, between 2018 and 2021. The average isolated proportions of the seven AMR pathogens were higher in Okayama compared to other prefectures: the worst (19.9%) was meropenem-resistant P. aeruginosa, the sixth worst (57.2%) was methicillin-resistant S. aureus, the eighth worst (3.3%) was vancomycin-resistant E. faecium, the second (37.8%) and fifth worst (17.6%) were cefotaxime-resistant E. coli and K. pneumoniae, respectively, and the fourth (49.9%) and third worst (8.7%) were levofloxacin-resistant E. coli and K. pneumoniae, respectively. Our study highlights the notably high prevalences of representative AMR pathogens in Okayama, suggesting the need for fundamental infection prevention and control by healthcare professionals, promoting antimicrobial stewardship, and educating undergraduates and postgraduates in Okayama. |
| Keywords | antimicrobial resistance antimicrobial stewardship epidemiology infection prevention and control Japan Nosocomial Infections Surveillance |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 255 |
| End Page | 262 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357626 |
| Web of Science KeyUT | 001026279600003 |
| Title Alternative | Experience with a nosocomial cluster of novel coronavirus infection and the cluster response algorithm |
|---|---|
| Author | Fujita, Koji| Ocho, Kazuki| Kadowaki, Tomoka| Yorifuji, Takashi| Otsuka, Fumio| |
| Abstract | The novel coronavirus disease (COVID-19) pandemic that began in 2019 is yet to end, as of the summer of 2022. During the pandemic, community-acquired infections spread easily to healthcare-associated facilities, resulting in COVID-19 clusters among high-risk individuals that have been difficult to contain. Our regional base hospital also experienced a nosocomial cluster of COVID-19 in October 2020 that took 30 days to contain and affected 9 hospital staff and 14 patients. Six patients died due to COVID-19, and six died due to COVID-19-related complications. Two patients were discharged alive. Patient characteristics included ① advanced age (79.0±8.1 years), ② dementia (64.3%), ③ low Prognostic Nutrition Index (31.1 ±7.9), ④ zinc deficiency (50.2±13.1μg/dL), ⑤ vitamin C deficiency (1.6±1.9μg/mL), ⑥ elevated urea nitrogen-to-creatinine ratio (27.4±23.5), ⑦ anticancer and immunosuppressive drug use (78.6%), and ⑧ malignancy (75.6%). This cluster had a very high mortality rate, but the viral spread was contained in a short period. Algorithmizing the cluster response was crucial to controlling this cluster. We report on our actual cluster response algorithm, as well as our strategy and response procedure during the pandemic. |
| Keywords | 新型コロナウイルス感染症（COVID-19） 院内クラスター（nosocomial cluster） 対応アルゴリズム（response algorithm） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2023-04-01 |
| Volume | volume135 |
| Issue | issue1 |
| Start Page | 22 |
| End Page | 33 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.135.22 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2023 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.135.22 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Namba, Takahiro| Takeuchi, Akihito| Matsumoto, Naomi| Tsuge, Mitsuru| Yashiro, Masato| Tsukahara, Hirokazu| Yorifuji, Takashi| |
| Keywords | Kawasaki disease (KD) birth order group childcare infectious diseases vasculitis |
| Published Date | 2023-03-28 |
| Publication Title | Frontiers in Pediatrics |
| Volume | volume11 |
| Publisher | Frontiers Media |
| Start Page | 1127053 |
| ISSN | 2296-2360 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Namba, Takeuchi, Matsumoto, Tsuge, Yashiro, Tsukahara and Yorifuji. |
| File Version | publisher |
| PubMed ID | 37056943 |
| DOI | 10.3389/fped.2023.1127053 |
| Web of Science KeyUT | 000965495400001 |
| Related Url | isVersionOf https://doi.org/10.3389/fped.2023.1127053 |
| JaLCDOI | 10.18926/AMO/65141 |
|---|---|
| FullText URL | 77_2_121.pdf |
| Author | Iguchi, Toshihiro| Matsui, Yusuke| Tomita, Koji| Uka, Mayu| Umakoshi, Noriyuki| Kawabata, Takahiro| Munetomo, Kazuaki| Nagata, Shoma| Araki, Motoo| Hiraki, Takao| |
| Abstract | Percutaneous cryoablation of renal tumors is widely used because of its high efficacy and safety. This high safety can be attributed, at least in part, to the visibility of the ablated area as an “ice ball”. This therapy has fewer complications (incidence, 0-7.2%) and is less invasive than surgery. Minor bleeding is inevitable in most kidney-related procedures, and indeed the most common complication of this therapy is bleeding (hematoma and hematuria). However, patients require treatment such as transfusion or transarterial embolization in only 0-4% of bleeding cases. Various other complications such as ureteral or collecting system injury, bowel injury, nerve injury, skin injury, infection, pneumothorax, and tract seeding also occur, but they are usually minor and asymptomatic. However, operators should know and avoid the various complications associated with this therapy. This study aimed to summarize the complications of percutaneous cryoablation for renal tumors and provide some techniques for achieving safe procedures. |
| Keywords | cryosurgery kidney neoplasms carcinoma renal cell complication |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 121 |
| End Page | 129 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094949 |
| Web of Science KeyUT | 000982503800001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ono-Minagi, Hitomi| Gojo, Nao| Nohno, Tsutomu| Inoue, Tsuyoshi| Ohuchi, Hideyo| Sakai, Takayoshi| |
| Keywords | Bacteria Oral hygiene Xerostomia Opportunistic infection Infection control Dysphagia |
| Published Date | 2023-02-17 |
| Publication Title | BMC Oral Health |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 108 |
| ISSN | 1472-6831 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 36805677 |
| DOI | 10.1186/s12903-023-02779-5 |
| Web of Science KeyUT | 000934505100004 |
| Related Url | isVersionOf https://doi.org/10.1186/s12903-023-02779-5 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Murakami, Hiroyuki| Matsuoka, Ken-Ichi| Asano, Takeru| Moriyama, Takashi| Matsumura, Akifumi| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Nishimori, Hisakazu| Fujii, Keiko| Fujii, Nobuharu| Toji, Tomohiro| Yoshino, Tadashi| Maeda, Yoshinobu| |
| Keywords | Refractory acute myeloid leukemia Transplant B-cell lymphoma-2 Azacitidine Venetoclax |
| Published Date | 2022-11-08 |
| Publication Title | Case Reports In Oncology |
| Volume | volume15 |
| Issue | issue3 |
| Publisher | Karger |
| Start Page | 974 |
| End Page | 979 |
| ISSN | 1662-6575 |
| NCID | AA12780955 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s). |
| File Version | publisher |
| PubMed ID | 36636684 |
| DOI | 10.1159/000526697 |
| Web of Science KeyUT | 000905485600025 |
| Related Url | isVersionOf https://doi.org/10.1159/000526697 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ojima, Hinako| Kuraoka, Sakiko| Okanoue, Shyoutarou| Okada, Hiroyuki| Gotoh, Kazuyoshi| Matsushita, Osamu| Watanabe, Akari| Yokota, Kenji| |
| Keywords | Helicobacter pylori nitrate-reducing bacteria IL-8 TNF-alpha cell cycle |
| Published Date | 2022-12-16 |
| Publication Title | Microorganisms |
| Volume | volume10 |
| Issue | issue12 |
| Publisher | MDPI |
| Start Page | 2495 |
| ISSN | 2076-2607 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 36557748 |
| DOI | 10.3390/microorganisms10122495 |
| Web of Science KeyUT | 000903731600001 |
| Related Url | isVersionOf https://doi.org/10.3390/microorganisms10122495 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwatani, Tsuguo| Saito, Shinya| |
| Keywords | parathyroid surgery prophylactic antibiotic risk factor surgical site infection thyroid surgery |
| Published Date | 2022-12-11 |
| Publication Title | International Wound Journal |
| Volume | volume2022 |
| Publisher | Wiley |
| ISSN | 1742-4801 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Authors. |
| File Version | publisher |
| PubMed ID | 36504428 |
| DOI | 10.1111/iwj.14046 |
| Web of Science KeyUT | 000896886400001 |
| Related Url | isVersionOf https://doi.org/10.1111/iwj.14046 |
| FullText URL | fulltext20221130-1.pdf |
|---|---|
| Author | Matsuo, Toshihiko| Iguchi, Masahiro| Morisato, Noriyasu| Murasako, Tatsuya| Hagiya, Hideharu| |
| Keywords | cataract surgery global action plan antimicrobial resistance appropriate use antibiotics oral intravenous topical povidone iodine conjunctival sac culture |
| Published Date | 2022-11-27 |
| Publication Title | International Journal of Environmental Research and Public Health |
| Volume | volume19 |
| Issue | issue23 |
| Publisher | MDPI AG |
| Start Page | 15796 |
| ISSN | 1660-4601 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| DOI | 10.3390/ijerph192315796 |
| JaLCDOI | 10.18926/AMO/64115 |
|---|---|
| FullText URL | 76_6_651.pdf |
| Author | Bright Osman Abugri| Matsusaki, Takashi| Ren, Wanxu| Morimatsu, Hiroshi| |
| Abstract | Maintaining perioperative normothermia decreases the post-surgery surgical site infection (SSI) rate. We investigated whether SSI is associated with intraoperative hypothermia in total hip (THA) and total knee (TKA) arthroplasties by retrospectively analyzing 297 THA and TKA cases. The patients’ intraoperative core body temperature (BT) was measured by bladder catheter or forehead sensor. We evaluated the associations between SSI and intraoperative BT and other variables and patient characteristics. Fifty-six patients (18.8%) had hypothermia (BT <36°C); 43 developed SSI (14.5%); only five had hypothermia (11.6%). Intraoperative hypothermia and SSI were not significantly associated. The SSI group had more men (34.9% vs. 18.1%) and THA patients (77.4%), a longer mean surgical duration (174.3 vs. 143.5 mins), and a higher average BT (36.4°C vs. 36.2°C) than the no-SSI group. The SSI patients had a higher intraoperative BT. A multivariable analysis revealed that SSI was associated with male sex (OR 2.3, 95%CI: 1.031-4.921, p=0.042), longer surgery (OR, 1.01, 95%CI: 1.003-1.017, p=0.004), THA (OR 3.6, 95%CI: 1.258-10.085, p=0.017), and intraoperative BT >36.0°C (OR 3.6, 95%CI: 1.367-9.475, p=0.009). Intraoperative hypothermia was not associated with SSI in adults who underwent THA or TKA. These results suggest that hypothermia might not be the problem for SSI. |
| Keywords | hypothermia surgical site infection total hip arthroplasty (THA) knee arthroplasty (TKA) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-12 |
| Volume | volume76 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 651 |
| End Page | 660 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36549767 |
| Web of Science KeyUT | 000905195100005 |
| JaLCDOI | 10.18926/AMO/64044 |
|---|---|
| FullText URL | 76_5_609.pdf |
| Author | Matsumoto, Ken| Fujishita, Keigo| Matsuda, Masayuki| Oka, Satoshi| Fujisawa, Yuka| Imai, Toshi| Machida, Takuya| |
| Abstract | A 69-year-old Japanese man with acute leukemia received post-transplant cyclophosphamide-based haploidentical stem cell transplantation (PTCY-haplo-SCT) but was readmitted with dyspnea and ground-glass-opacities of the lungs. Bronchoscopy showed inflammatory changes with no signs of infection. He received steroids but required intubation as his condition deteriorated. In addition to antithymocyte globulin and cyclophosphamide, we administered ruxolitinib but failed to save him. Autopsy findings revealed fibrotic nonspecific interstitial pneumonia (NSIP) without evidence of organizing pneumonia or infection. Thus, we diagnosed idiopathic pneumonia syndrome (IPS). As far as our knowledge, this is the first case of IPS with NSIP histology after PTCY-haplo-SCT. |
| Keywords | idiopathic pneumonia syndrome ruxolitinib post-transplant cyclophosphamide-based haploidentical stem cell transplantation nonspecific interstitial pneumonia |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-10 |
| Volume | volume76 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 609 |
| End Page | 615 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36352810 |
| Web of Science KeyUT | 000884907100016 |
| FullText URL | fulltext20221102-2.pdf |
|---|---|
| Author | Hagiya, Hideharu| Onishi, Yuji| Shinohara, Natsumi| Tokuyasu, Mayumi| Imanishi, Aki| Fukushima, Shinnosuke| Nahar, Lutfun| Iio, Koji| Otsuka, Fumio| |
| Keywords | Aging society Antimicrobial resistance Carbapenem-resistant Enterobacteriaceae Extended-spectrum beta-lactamase Infection prevention and control |
| Note | © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jiac.2022.07.014] . | |
| Published Date | 2022-11 |
| Publication Title | Journal of Infection and Chemotherapy |
| Volume | volume28 |
| Issue | issue11 |
| Publisher | Elsevier BV |
| Start Page | 1578 |
| End Page | 1581 |
| ISSN | 1341-321X |
| NCID | AA11057978 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. |
| File Version | author |
| PubMed ID | 35921967 |
| DOI | 10.1016/j.jiac.2022.07.014 |
| Web of Science KeyUT | 000863109600009 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jiac.2022.07.014 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sumi, Tomonari| Harada, Kouji| |
| Published Date | 2022-08-19 |
| Publication Title | ISCIENCE |
| Volume | volume25 |
| Issue | issue8 |
| Publisher | CELL PRESS |
| Start Page | 104723 |
| ISSN | 2589-0042 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s). |
| File Version | publisher |
| PubMed ID | 35813874 |
| DOI | 10.1016/j.isci.2022.104723 |
| Web of Science KeyUT | 000843628600010 |
| Related Url | isVersionOf https://doi.org/10.1016/j.isci.2022.104723 |
