result 127 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kobatake, Tomomi| Ogino, Keiki| Sakae, Hiroyuki| Gotoh, Kazuyoshi| Watanabe, Akari| Matsushita, Osamu| Okada, Hiroyuki| Yokota, Kenji| |
| Keywords | disulfiram Helicobacter pylori urease vacuolating toxin CagA |
| Published Date | 2021-05-12 |
| Publication Title | Infection and Drug Resistance |
| Volume | volume14 |
| Publisher | Dove Medical Press Ltd |
| Start Page | 1757 |
| End Page | 1764 |
| ISSN | 1178-6973 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Kobatake et al. |
| File Version | publisher |
| PubMed ID | 34012274 |
| DOI | 10.2147/IDR.S299177 |
| NAID | 120007042392 |
| Web of Science KeyUT | 000653055700001 |
| Related Url | isVersionOf https://doi.org/10.2147/IDR.S299177 |
| JaLCDOI | 10.18926/AMO/61903 |
|---|---|
| FullText URL | 75_2_213.pdf |
| Author | Miyashita, Manabi| Saragai, Yousuke| Fujimoto, Tsuyoshi| Tanaka, Shouichi| Aoki, Hideki| Sato, Yumiko | |
| Abstract | A 75-year-old Japanese man visited our hospital for further examination of liver tumors. He had a history of successful hepatitis C virus (HCV) eradication and therapy for hepatocellular carcinoma (HCC) at another hospital. Magnetic resonance imaging (MRI) revealed two tumors in the liver. He underwent anterior inferior (S5) and posterior inferior (S6) subsegmentectomy of the liver. Microscopic examination found that one tumor was HCC while the other was cholangiolocellular carcinoma (CoCC). We experienced a rare case of liver cancer with two synchronous pathologies, HCC and CoCC. |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 213 |
| End Page | 218 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953428 |
| NAID | 120007029884 |
| JaLCDOI | 10.18926/AMO/61895 |
|---|---|
| FullText URL | 75_2_177.pdf |
| Author | Inoue, Madoka| Noda, Tomoyuki| Uehara, Takenori| Tetsunaga, Tomonori| Yamada, Kazuki| Saito, Taichi| Shimamura, Yasunori| Yamakawa, Yasuaki| Ozaki, Toshifumi| |
| Abstract | This retrospective study sought to elucidate the incidence rates of roof impaction (RI) and marginal impaction (MI) and radiological and clinical outcomes of open reduction and internal fixation (ORIF) for RI and MI in geriatric acetabular fractures. The cases of 68 patients aged ≥ 65 years (mean 71 years) treated with ORIF were analyzed. MI was present in 12 fractures (67%) and an RI of the weight-bearing surface was present in 24 (46%) of the potential fracture types. Regarding the reduction quality, 54% of the reductions were graded as anatomical, 37% as imperfect, and 9% as poor. In the clinical evaluations of the 45 patients who had > 1-year follow-up (follow-up rate: 66.2%), 18% were graded as excellent, 53% as good, 16% as fair, and 13% as poor. An anatomic reduction was strongly associated with good or excellent clinical and radiological outcomes. CT was superior to radiographs for detecting the residual displacement postoperatively. Postoperative deep infection occurred in four patients. Three patients (6.7%) underwent a total hip arthroplasty conversion due to secondary osteoarthritis of the hip. We recommend ORIF as the preferred surgical treatment option for displaced acetabular fractures in elderly patients. |
| Keywords | acetabular fracture osteosynthesis marginal impaction roof impaction elderly patient |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 177 |
| End Page | 185 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953423 |
| NAID | 120007029891 |
| JaLCDOI | 10.18926/AMO/61877 |
|---|---|
| FullText URL | 75_2_115.pdf |
| Author | Hitomi, Nishizaki| Yoshinari, Morimoto| Yamada, Shin-ichi| Kurita, Hiroshi| Tanaka, Akira| Yamaguchi, Akira| Miyata, Masaru| Yoshikawa, Hiromasa | Yanamoto, Souichi| Imai, Yutaka| |
| Abstract | The aim of this study was to investigate the awareness and experience, among dental practitioners, of adverse events resulting from dental treatment of patients undergoing therapy with drugs that affect the immune system [angiogenesis inhibitors, biological agents, immunosuppressants, and disease-modifying anti-rheumatic drugs (DMARDs)]. For this purpose, a nationwide questionnaire survey was conducted. Questionnaires were sent to 2,050 dentists, of which 206 (10.1%) were completed and returned. The results showed that most dentists were aware of complications associated with dental treatment of patients treated with drugs that affect the immune system, and about half had actually experienced such complications. Delayed wound healing, osteonecrosis of the jaw (ONJ), and postoperative infections were reported. Whereas approximately 50% of dentists did not discontinue the drugs during dental treatment, about 18% did. During temporary drug discontinuation, some patients experienced aggravation of the primary disease, such as worsening of rheumatism, growth of tumors, and rejection reactions of transplanted organs. As for medical cooperation, only less than half of the dentists were asked for oral hygiene management by a physician prior to starting the drug treatment. Prospective studies are needed because evidence for dental treatments in patients treated with these drugs remains limited. |
| Keywords | angiogenesis inhibitor biological agent disease-modifying antirheumatic drug (DMARD) immunosuppressant medication-related osteonecrosis of the jaw (MRONJ) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 115 |
| End Page | 123 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953417 |
| NAID | 120007029906 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | YASUHARA, Takao| MURAI, Satoshi| MIKUNI, Nobuhiro| MIYAMOTO, Susumu| DATE, Isao| |
| Keywords | artificial bone cranioplasty infection re-operation titanium plate |
| Published Date | 2020 |
| Publication Title | Neurologia medico-chirurgica |
| Volume | volume60 |
| Issue | issue7 |
| Publisher | The Japan Neurosurgical Society |
| Start Page | 337 |
| End Page | 350 |
| ISSN | 0470-8105 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by The Japan Neurosurgical Society |
| PubMed ID | 32536658 |
| DOI | 10.2176/nmc.oa.2020-0051 |
| Web of Science KeyUT | 000548315700003 |
| Related Url | isVersionOf https://doi.org/10.2176/nmc.oa.2020-0051 |
| JaLCDOI | 10.18926/AMO/61204 |
|---|---|
| FullText URL | 74_6_461.pdf |
| Author | Kono, Yoshiyasu| Kanzaki, Hiromitsu| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Abstract | Gastric cancer usually arises in middle-aged to older patients, and is rarely found in younger patients. The clin-ical characteristics, etiology, prognosis, preventive methods and treatment of gastric cancer in young patients have not been fully investigated because of its low prevalence. In this review, we discuss the current under-standing and clinical problems associated with gastric cancer in young patients. Helicobacter pylori (H. pylori), which is a major cause of gastric cancer, especially in older populations, is closely associated with gastric cancer in young patients as well as in older patients. Gastric cancer in young patients tends to be diagnosed at an advanced stage with alarm symptoms. However, young patients with advanced gastric cancer tend to have a favorable general condition and organ function, so they can tolerate intensive systematic chemotherapy. Unfortunately, the prognosis of gastric cancer in young patients with an advanced stage is not favorable. We should not take this rare disease lightly, given its poor prognosis if patients are diagnosed at an unresectable stage. The evaluation of the H. pylori infection status and performance of H. pylori eradication therapy to prevent gastric cancer in young patients as well as the development of more intensive chemotherapy regimens for unre-sectable gastric cancer in young patients are warranted. |
| Keywords | gastric cancer young patients Helicobacter pylori |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-12 |
| Volume | volume74 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 461 |
| End Page | 466 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33361865 |
| Web of Science KeyUT | 000601203600001 |
| NAID | 120006948954 |
| FullText URL | JIC_26.pdf |
|---|---|
| Author | Haruki, Yuto| Hagiya, Hideharu| Haruki, Mai| Inoue, Yuta| Sugiyama, Tetsuhiro| |
| Keywords | Acute kidney injury β-lactams Piperacillin/tazobactam Vancomycin |
| Note | This fulltext is available in Oct. 2021.| |
| Published Date | 2020-10 |
| Publication Title | Journal of Infection and Chemotherapy |
| Volume | volume26 |
| Issue | issue10 |
| Publisher | Elsevier |
| Start Page | 1026 |
| End Page | 1032 |
| ISSN | 1341-321X |
| NCID | AA11057978 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32561128 |
| DOI | 10.1016/j.jiac.2020.05.012 |
| Web of Science KeyUT | 000561076200003 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jiac.2020.05.012 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Saito, Kenki| Aokage, Toshiyuki| Sato, Takayuki| Tsukahara, Kohei| Tokioka, Fumiaki| Otake, Takanao| Irie, Hiromasa| Ueda, Yasunori| |
| Keywords | Stenotrophomonas maltophilia Severe pneumonia Acute panmyelosis with myelofibrosis Acute myeloid leukemia Extracorporeal membrane oxygenation |
| Published Date | 2020-12 |
| Publication Title | Respiratory Medicine Case Reports |
| Volume | volume31 |
| Publisher | Elsevier |
| Start Page | 101224 |
| ISSN | 2213-0071 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Author(s). |
| File Version | publisher |
| PubMed ID | 32995263 |
| DOI | 10.1016/j.rmcr.2020.101224 |
| Web of Science KeyUT | 000600668000086 |
| Related Url | isVersionOf https://doi.org/10.1016/j.rmcr.2020.101224 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ishihara, Ryo| Matsumura, Kentarou| Jones, Jordan Elouise| Yuhao, Ji| Fujisawa, Ryusuke| Nagaya, Naohisa| Miyatake, Takahisa| |
| Keywords | Beetle Death feigning Selection experiment Species comparison Thanatosis Tonic immobility Tribolium |
| Note | This fulltext is available on Oct. 2021.| |
| Published Date | 2020-10-20 |
| Publication Title | Journal of Ethology |
| Volume | volume39 |
| Publisher | Springer |
| Start Page | 107 |
| End Page | 113 |
| ISSN | 0289-0771 |
| NCID | AA10754455 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1007/s10164-020-00680-0 |
| Web of Science KeyUT | 000581785500001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10164-020-00680-0 |
| JaLCDOI | 10.18926/AMO/60805 |
|---|---|
| FullText URL | 74_5_435.pdf |
| Author | Fujishita, Keigo| Oka, Satoshi| Kamei, Katsuhiko| Tani, Katsuma| Fujisawa, Yuka| Kitamura, Wataru| Machida, Takuya| Imai, Toshi| |
| Abstract | A 53-year-old man was diagnosed with acute myeloid leukemia, which was refractory to chemotherapies. Systemic papules appeared afterward. The skin biopsies revealed filamentous fungal infection including fusariosis. Despite antifungal therapy, the infection did not resolve, because neutropenia persisted with the leukemia. He underwent hematopoietic stem cell transplantation (HSCT) to overcome the leukemia and restore normal hematopoiesis but died from fusariosis just before engraftment. Fusarium fujikuroi species complex was detected in blood cultures with poor antifungal susceptibility. Because restoring normal hematopoiesis is important in the treatment of fusariosis, HSCT might be considered for patients with persistent pancytopenia. |
| Keywords | disseminated fusariosis Fusarium fujikuroi species complex allogeneic hematopoietic stem cell transplantation acute myeloid leukemia |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-10 |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 435 |
| End Page | 441 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106701 |
| Web of Science KeyUT | 000581970100010 |
| NAID | 120006892931 |
| JaLCDOI | 10.18926/AMO/59961 |
|---|---|
| FullText URL | 74_3_261.pdf |
| Author | Nakahara, Keiichi| Ikeda, Tokunori| Takamatsu, Koutaro| Tawara, Nozomu| Hara, Kentaro| Enokida, Yuki| Tanoue, Naomi| Narita, Sawana| Fujii, Akiko| Yamanouchi, Yoshinori| Morinaga, Jun| Yamashita, Satoshi| |
| Abstract | Muscle biopsy can be used to confirm the diagnosis of neuromuscular diseases. However, it is unclear whether antibiotic prophylaxis prior to muscle biopsy is needed to prevent surgical site infection (SSI). We are conducting a phase 2, single-center, open-labeled, prospective randomized trial to clarify the need for antibiotic prophylaxis in patients at low risk for SSI undergoing muscle biopsy. Patients will be randomized to an antibiotic prophylaxis group or a control group, and the incidence of SSI will be compared between the groups. Our findings will clarify the need for antibiotic prophylaxis in this patient population. |
| Keywords | muscle biopsy antibiotic prophylaxis |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 261 |
| End Page | 264 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577026 |
| Web of Science KeyUT | 000543363400011 |
| NAID | 120006862802 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takao, Miyuki| Yoshioka, Nori| Hagiya, Hideharu| Deguchi, Matsuo| Kagita, Masanori| Tsukamoto, Hiroko| Hidaka, Yoh| Tomono, Kazunori| Tobe, Toru| |
| Keywords | Blood and body fluid exposure Cytomegalovirus Healthcare workers Occupational infection Seroconversion |
| Published Date | 2020-03-10 |
| Publication Title | Journal of Infection and Chemotherapy |
| Volume | volume26 |
| Issue | issue7 |
| Publisher | Elsevier |
| Start Page | 681 |
| End Page | 684 |
| ISSN | 1341-321X |
| NCID | AA11057978 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. |
| File Version | author |
| PubMed ID | 32169323 |
| DOI | 10.1016/j.jiac.2020.02.011 |
| Web of Science KeyUT | 000540280300007 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jiac.2020.02.011 |
| FullText URL | K0006101_abstract_review.pdf K0006101_summary.pdf K0006101_fulltext.pdf |
|---|---|
| Author | Morishita, Michiko| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6101号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nguyen, Thuong T.| Miyake, Ayumi| Tran, Tu T. M.| Tsuruta, Takeshi| Nishino, Naoki| |
| Keywords | cowshed environment microbiota uterus |
| Published Date | 2019-11-21 |
| Publication Title | Animals |
| Volume | volume9 |
| Issue | issue12 |
| Publisher | MDPI |
| Start Page | 1007 |
| ISSN | 2076-2615 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31766341 |
| DOI | 10.3390/ani9121007 |
| Web of Science KeyUT | 000506636400007 |
| Related Url | isVersionOf https://doi.org/10.3390/ani9121007 |
| JaLCDOI | 10.18926/AMO/57948 |
|---|---|
| FullText URL | 74_1_17.pdf |
| Author | Ishii, Kenzo| Morimatsu, Hiroshi| Ono, Kazumi| Miyasho, Koji| |
| Abstract | We performed a retrospective cohort study of 911 high-energy trauma patients who underwent chest CT scans at least twice after admission. We hypothesized that in high-energy trauma patients, a high-inspired oxygen concentration delivered after admission results in dorsal atelectasis. The study’s primary outcome was dorsal atelectasis formation diagnosed based on CT images. We defined dorsal atelectasis as the presence of atelectasis at ≥ 10 mm thick on CT images. We defined high-inspired oxygen concentration as >60% oxygen delivered between two CT scans. Four hundred sixty-five patients (51.0%) developed atelectasis according to the second CT scan, and 338 (37.1%) received a high-inspired oxygen concentration. A univariate analysis showed that the rate of the high-inspired oxygen concentration in the atelectasis group was significantly higher than that in the non-atelectasis group (43.4% vs. 30.1%, p<0.001). However, a logistic regression analysis showed that there was no significant relationship between the oxygen concentration and the formation of dorsal atelectasis (OR: 1.197, 95%CI: 0.852-1.683, p=0.30). Age, the Injury Severity Score, BMI, and smoking were found to be risk factors of dorsal atelectasis formation in high-energy trauma patients. There was no relationship between the oxygen concentration and atelectasis formation in our series of high-energy trauma patients. |
| Keywords | trauma patient dorsal atelectasis oxygen concentration |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-02 |
| Volume | volume74 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 17 |
| End Page | 26 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32099244 |
| Web of Science KeyUT | 000516606200003 |
| NAID | 120006795615 |
| FullText URL | CORR477_8_1892.pdf |
|---|---|
| Author | Kunisada, Toshiyuki| Fujiwara, Tomohiro| Hasei, Joe| Nakata, Eiji| Senda, Masuo| Ozaki, Toshifumi| |
| Published Date | 2019-08 |
| Publication Title | Clinical Orthopaedics and Related Research |
| Volume | volume477 |
| Issue | issue8 |
| Publisher | Lippincott, Williams & Wilkins |
| Start Page | 1892 |
| End Page | 1901 |
| ISSN | 0009-921X |
| NCID | AA00607942 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30985613 |
| DOI | 10.1097/CORR.0000000000000764 |
| Web of Science KeyUT | 000509664400024 |
| Related Url | isVersionOf https://doi.org/10.1097/CORR.0000000000000764 |
| FullText URL | JVMS81_8_1191.pdf |
|---|---|
| Author | Ogawa, Hirohito| Hirayama, Haruko| Tanaka, Satsuki| Yata, Norio| Namba, Hikaru| Yamashita, Nobuko| Yonemitsu, Kenzo| Maeda, Ken| Mominoki, Katsumi| Yamada, Masao| |
| Keywords | animal experimental facility domestic pig hepatitis E virus zoonosis |
| Published Date | 2019-08-24 |
| Publication Title | Journal of Veterinary Medical Science |
| Volume | volume81 |
| Issue | issue8 |
| Publisher | The Japanese Society of Veterinary Science |
| Start Page | 1191 |
| End Page | 1196 |
| ISSN | 0916-7250 |
| NCID | AA10796138 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©2019 The Japanese Society of Veterinary Science |
| File Version | publisher |
| PubMed ID | 31281141 |
| DOI | 10.1292/jvms.19-0086 |
| Web of Science KeyUT | 000492854900021 |
| Related Url | isVersionOf https://doi.org/10.1292/jvms.19-0086 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Saito, Taichi| Noda, Tomoyuki| Kondo, Hiroya| Demiya, Koji| Nezu, Satoshi| Yokoo, Suguru| Matsuhashi, Minami| Uehara, Takenori| Shimamura, Yasunori| Kodama, Masayuki| Ozaki, Toshifumi| |
| Keywords | Hand Induced membrane Masquelet technique Septic arthritis The small joint |
| Published Date | 2020-02-29 |
| Publication Title | Trauma Case Reports |
| Volume | volume25 |
| Start Page | 100268 |
| ISSN | 23526440 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Authors. Published by Elsevier Ltd. |
| File Version | publisher |
| PubMed ID | 1890833 |
| DOI | 10.1016/j.tcr.2019.100268 |
| Related Url | isVersionOf https://doi.org/10.1016/j.tcr.2019.100268 |
| JaLCDOI | 10.18926/AMO/56861 |
|---|---|
| FullText URL | 73_3_197.pdf |
| Author | Nishimura, Takeshi| Naito, Hiromichi| Matsuyama, Shigenari| Ishihara, Satoshi| Nakao, Atsunori| Nakayama, Shinichi| |
| Abstract | Japan's population has been skewing toward the elderly, but the outcomes of advanced elderly trauma are not clear. Here we compared the outcomes of very elderly trauma patients (≧85 years old) with those of 65- to 84-year-old trauma patients. We retrospectively reviewed the medical records of patients treated at Hyogo Emergency Medical Center from August 2010 to August 2016; 631 patients were entered in the study. We divided them into the younger geriatrics (YG group, 65-84 years old: n=534) and older geriatrics (OG group, ≧85 years old: n=97). The group’s patient characteristics, mortality, 1-year survival rate, and Barthel index were tabulated and compared. The patients’ mean age was 75.6±7.5 years. There was no significant difference in mortality between the YG and OG groups (9.6% vs. 15.1%, odds ratio [OR] 1.73; 95% confidence interval [CI] 0.93-3.23, p=0.083). The 1-year survival rate (94.4% vs. 77.8%, OR 0.19, 95% CI 0.07-0.51; p<0.01) and Barthel index (Median score; 100 (IQR: 85-100) vs. 80 (IQR: 15-95), OR 0.98, 95% CI 0.97 to 0.99, p<0.01) differed significantly between the groups. Our study did not find a significant difference in-hospital mortality between patients in the YG group and those in the OG group. |
| Keywords | aged injury mortality morbidity trauma |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 197 |
| End Page | 203 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235966 |
| JaLCDOI | 10.18926/AMO/56860 |
|---|---|
| FullText URL | 73_3_189.pdf |
| Author | Sakamoto, Shinji| Kawai, Hiroki| Okahisa, Yuko| Tsutsui, Ko| Kanbayashi, Takashi| Tanaka, Keiko| Mizuki, Yutaka| Takaki, Manabu| Yamada, Norihito| |
| Abstract | Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti-NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry. |
| Keywords | NMDAR encephalitis psychiatric symptom schizophrenia mood disorder |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 189 |
| End Page | 195 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235965 |
