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JaLCDOI 10.18926/AMO/68362
FullText URL 79_1_051.pdf
Author Miura, Taro| Kawasaki, Yoichi| Hamano, Hirofumi| Zamami, Yoshito| Sendo, Toshiaki|
Abstract Photoinitiators are used in the manufacture of many daily products, and may produce harmful effects due to their cytotoxicity. They have also been detected in human serum. Here, we investigated the histamine-producing effects in HMC-1 cells and the inflammatory cytokine release effects in RAW264 cells for four photoinitiators: 1-hydroxycyclohexyl phenyl ketone; 2-isopropylthioxanthone; methyl 2-benzoylbenzoate; and 2-methyl-4´-(methylthio)-2-morpholinopropiophenone. All four promoted histamine production in HMC-1 cells; however, they did not significantly affect the release of inflammatory cytokines in RAW264 cells. These findings suggest that these four photoinitiators induce inflammatory cytokine-independent histamine production, potentially contributing to histamine-mediated chronic inflammation in vitro.
Keywords photoinitiator ink injection histamine inflammation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 51
End Page 58
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012160
Web of Science KeyUT 001440463800007
JaLCDOI 10.18926/AMO/68354
FullText URL 79_1_009.pdf
Author Ikeya, Nanami| Okita, Atsushi| Hashida, Shinsuke| Yamamoto, Sumiharu| Ikeda, Hirokuni| Tsukuda, Kazunori| Toyooka, Shinichi|
Abstract Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy.
Keywords sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 9
End Page 19
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012155
Web of Science KeyUT 001440463800002
FullText URL fulltext20250213-02.pdf suppl20250213-02.pdf
Author Mukohara, Fumiaki| Iwata, Kazuma| Ishino, Takamasa| Inozume, Takashi| Nagasaki, Joji| Ueda, Youki| Suzawa, Ken| Ueno, Toshihide| Ikeda, Hideki| Kawase, Katsushige| Saeki, Yuka| Kawashima, Shusuke| Yamashita, Kazuo| Kawahara, Yu| Nakamura, Yasuhiro| Honobe-Tabuchi, Akiko| Watanabe, Hiroko| Dansako, Hiromichi| Kawamura, Tatsuyoshi| Suzuki, Yutaka| Honda, Hiroaki| Mano, Hiroyuki| Toyooka, Shinichi| Kawazu, Masahito| Togashi, Yosuke|
Keywords cancer immunology somatic mutation T cell tumor-infiltrating lymphocytes
Note This is an Accepted Manuscript of an article published by Proceedings of the National Academy of Sciences.| This fulltext file will be available in Feb. 2025.|
Published Date 2024-08-21
Publication Title Proceedings of the National Academy of Sciences
Volume volume121
Issue issue35
Publisher Proceedings of the National Academy of Sciences
Start Page e2320189121
ISSN 0027-8424
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 the Author(s).
File Version author
PubMed ID 39167601
DOI 10.1073/pnas.2320189121
Web of Science KeyUT 001408603100001
Related Url isVersionOf https://doi.org/10.1073/pnas.2320189121
FullText URL fulltext.pdf
Author Yamada, Yuto| Fujiwara, Masaki| Nakaya, Naoki| Otsuki, Koji| Shimazu, Taichi| Fujimori, Maiko| Hinotsu, Shiro| Nagoshi, Kiwamu| Uchitomi, Yosuke| Inagaki, Masatoshi|
Keywords bipolar disorder cancer screening COVID-19 healthcare disparities schizophrenia
Published Date 2025-02-02
Publication Title Psychiatry and Clinical Neurosciences Reports
Volume volume4
Issue issue1
Publisher Wiley
Start Page e70062
ISSN 2769-2558
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 39902101
DOI 10.1002/pcn5.70062
Web of Science KeyUT 001410823100001
Related Url isVersionOf https://doi.org/10.1002/pcn5.70062
FullText URL fulltext.pdf
Author Kuribayashi, Tadahiro| Kinoshita, Rie| Ninomiya, Kiichiro| Makimoto, Go| Kubo, Toshio| Rai, Kammei| Ichihara, Eiki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki| Toyooka, Shinichi| Sakaguchi, Masakiyo| Ohashi, Kadoaki|
Keywords S100A8/A9 Lung cancer Immune checkpoint inhibitors
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-025-87232-z|
Published Date 2025-01-20
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 2577
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 39833332
DOI 10.1038/s41598-025-87232-z
Web of Science KeyUT 001400880600002
Related Url isVersionOf https://doi.org/10.1038/s41598-025-87232-z
FullText URL fulltext.pdf
Author Kawana, Shinichi| Okazaki, Mikio| Sakaue, Tomohisa| Hashimoto, Kohei| Nakata, Kentaro| Choshi, Haruki| Tanaka, Shin| Miyoshi, Kentaroh| Ohtani, Shinji| Ohara, Toshiaki| Sugimoto, Seiichiro| Matsukawa, Akihiro| Toyooka, Shinichi|
Keywords lung transplantation ischemia-reperfusion injury donation after circulatory death nuclear receptor subfamily 4 group A member 1 endothelial cell
Published Date 2024-10-05
Publication Title The Journal of Heart and Lung Transplantation
Volume volume44
Issue issue2
Publisher Elsevier
Start Page 249
End Page 260
ISSN 1053-2498
NCID AA10796579
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Authors.
File Version publisher
PubMed ID 39369968
DOI 10.1016/j.healun.2024.09.028
Web of Science KeyUT 001416964100001
Related Url isVersionOf https://doi.org/10.1016/j.healun.2024.09.028
JaLCDOI 10.18926/AMO/67871
FullText URL 78_6_453.pdf
Author Kawata, Yujiro| Watanabe, Kenta| Tokiya, Ryoji| Matsuno, Takeshi| Tanaka, Ryo| Taira, Naruto| Katsui, Kuniaki|
Abstract Radiation-induced angiosarcoma (RIAS) is a rare, late adverse event of radiotherapy comprising approximately half of all radiation-induced sarcomas. It has a relatively short latency period and generally unfavorable prognosis. This study presents a case of RIAS that developed 5 years and 11 months after the completion of hypofractionated radiotherapy (42.56 Gy/16 fractions) following partial mastectomy. The patient was diagnosed with RIAS 10 months after the onset of skin redness. She underwent skin tumor resection, followed by paclitaxel, then pazopanib administration, but no radiotherapy. At 6 years and 2 months after surgery, no RIAS recurrence has been detected.
Keywords breast cancer hypofractionated radiotherapy radiation-induced angiosarcoma
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-12
Volume volume78
Issue issue6
Publisher Okayama University Medical School
Start Page 453
End Page 458
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39719318
Web of Science KeyUT 001397808000001
FullText URL fulltext.pdf
Author Otani, Yusuke| Tanaka, Atsushi| Maekawa, Masaki| Peña, Tirso| Rogachevskaya, Anna| Ando, Teruhiko| Itano, Takuto| Katayama, Haruyoshi| Nakata, Eiji| Ozaki, Toshifumi| Toyooka, Shinichi| Doihara, Hiroyoshi| Roehrl, Michael H.| Fujimura, Atsushi|
Keywords C1orf50 Luminal A breast cancer Cell cycle Immune evasion YAP/TAZ
Note The version of record of this article, first published in Breast Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12282-024-01653-8|
Published Date 2024-11-28
Publication Title Breast Cancer
Volume volume32
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 292
End Page 305
ISSN 1340-6868
NCID AA1103354X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39604563
DOI 10.1007/s12282-024-01653-8
Web of Science KeyUT 001365140400001
Related Url isVersionOf https://doi.org/10.1007/s12282-024-01653-8
FullText URL fulltext.pdf
Author Futagawa, Mashu| Okazaki, Tetsuya| Nakata, Eiji| Fukano, Chika| Osumi, Risa| Kato, Fumino| Urakawa, Yusaku| Yamamoto, Hideki| Ozaki, Toshifumi| Hirasawa, Akira|
Note The version of record of this article, first published in Human Genome Variation, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41439-024-00299-4|
Published Date 2024-11-26
Publication Title Human Genome Variation
Volume volume11
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 42
ISSN 2054-345X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39592598
DOI 10.1038/s41439-024-00299-4
Web of Science KeyUT 001363412200001
Related Url isVersionOf https://doi.org/10.1038/s41439-024-00299-4
FullText URL K0007108_abstract_review.pdf K0007108_fulltext.pdf K0007108_summary.pdf
Author HNIN WINT WINT SWE|
Published Date 2024-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7108号
Granted Date 2024-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2024 The Author(s).
FullText URL K0007105_abstract_review.pdf K0007105_fulltext.pdf
Author TAKAHASHI, Tetta|
Published Date 2024-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7105号
Granted Date 2024-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2024 Takahashi, Tomonobu, Kinoshita, Yamamoto, Murata, Komalasari, Chen, Jiang, Gohara, Ochi, Ruma, Sumardika, Zhou, Honjo, Sakaguchi, Yamauchi, Kuribayashi, Kondo, Inoue, Futami, Toyooka, Zamami and Sakaguchi.
FullText URL K0007100_abstract_review.pdf K0007100_fulltext.pdf K0007100_summary.pdf
Author JIANG, FAN|
Published Date 2024-09-25
Content Type Thesis or Dissertation
Grant Number 甲第7100号
Granted Date 2024-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2024 Jiang, Chen, Tomonobu, Kinoshita, Komalasari, Kasano-Camones, Ninomiya, Murata, Yamamoto, Gohara, Ochi, Ruma, Sumardika, Zhou, Honjo, Sakaguchi, Yamauchi, Kuribayashi, Futami, Kondo, Inoue, Toyooka and Sakaguchi.
FullText URL fulltext.pdf
Author Mamori, Tomoka| Tanioka, Maki| Takada, Kenji| Hamano, Hirofumi| Tsukioki, Takahiro| Takahashi, Yuko| Iwatani, Tsuguo| Shien, Tadahiko| Toyooka, Shinichi|
Note The version of record of this article, first published in BioDrugs, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40259-024-00686-x|
Published Date 2024-10-16
Publication Title BioDrugs
Volume volume39
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 131
End Page 142
ISSN 1173-8804
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39412713
DOI 10.1007/s40259-024-00686-x
Web of Science KeyUT 001333384600001
Related Url isVersionOf https://doi.org/10.1007/s40259-024-00686-x
FullText URL fulltext20241023-01.pdf fig1_20241023-01.pdf fig2_20241023-01.pdf fig3_20241023-01.pdf fig4_20241023-01.pdf fig5_20241023-01.pdf fig6_20241023-01.pdf fig7_20241023-01.pdf fig8_20241023-01.pdf fig9_20241023-01.pdf fig10_20241023-01.pdf table20241023-01.pdf
Author Nakashima, Masahiro| Fukui, Ryohei| Sugimoto, Seiichiro| Iguchi, Toshihiro|
Keywords Chronic lung allograft dysfunction Lung transplantation Single photon emission computed tomography Deep learning Convolutional neural network
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s12194-024-00853-3| This fulltext file will be available in Oct. 2025.|
Published Date 2024-10-23
Publication Title Radiological Physics and Technology
Volume volume18
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 47
End Page 57
ISSN 1865-0333
NCID AA12236881
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s), under exclusive licence to Japanese Society of Radiological Technology and Japan Society of Medical Physics 2024
File Version author
PubMed ID 39441494
DOI 10.1007/s12194-024-00853-3
Web of Science KeyUT 001340532100001
Related Url isVersionOf https://doi.org/10.1007/s12194-024-00853-3
JaLCDOI 10.18926/AMO/67665
FullText URL 78_5_407.pdf
Author Shimoyama, Kyoko| Nakajima, Atsushi| Minari, Yoshimitsu|
Abstract Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but they have been known to cause immune-related adverse events (irAEs) by promoting T-cell activation. Neurological irAEs are rare (1%) but have a high fatality rate (11.5%). Here we report the first case of Bickerstaff brainstem encephalitis (BBE) induced by an ICI. A woman in her 60s with metastatic breast cancer was treated with atezolizumab plus nab-paclitaxel once intravenously. Eighteen days later, she lost consciousness with ophthalmoplegia and was diagnosed with a neurological irAE. She recovered consciousness immediately with the administration of intravenous immunoglobulin (IVIG) but suffered severe permanent peripheral neuropathy. Although it is just one case, this experience shows that BBE occurring as a neurological irAE of ICI cancer treatment may be associated with more severe outcomes than conventional BBE in metastatic cancer. Creating a system for multidisciplinary treatment is essential for ICI therapy.
Keywords Bickerstaff brainstem encephalitis immune checkpoint inhibitor atezolizumab neurological immune-related adverse event breast cancer
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-10
Volume volume78
Issue issue5
Publisher Okayama University Medical School
Start Page 407
End Page 412
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39467659
Web of Science KeyUT 001343346400007
FullText URL fulltext20241015-01.pdf fig20241015-01.pdf
Author Ninomiya, Kiichiro| Ennishi, Daisuke| Okamoto, Kunio| Ando, Midori| Nakamura, Satoko| Tomida, Shuta| Ayada, Yoshiyuki| Makimoto, Go| Ichihara, Eiki| Okita, Natsuko| Toyooka, Shinichi| Maeda, Yoshinobu| Tabata, Masahiro|
Note This is an Accepted Manuscript of an article published by American Society of Clinical Oncology (ASCO).| This fulltext file will be available in Sep. 2025.|
Published Date 2024-09-19
Publication Title JCO Precision Oncology
Volume volume8
Publisher American Society of Clinical Oncology (ASCO)
Start Page e2400228
ISSN 2473-4284
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by American Society of Clinical Oncology.
File Version author
PubMed ID 39298692
DOI 10.1200/po.24.00228
Web of Science KeyUT 001328214400001
Related Url isVersionOf https://doi.org/10.1200/po.24.00228
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2023 Sunada Prize)
Author Matsubara, Kei|
Publication Title Journal of Okayama Medical Association
Published Date 2024-08-01
Volume volume136
Issue issue2
Start Page 54
End Page 56
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.136.54
language Japanese
Copyright Holders Copyright (c) 2024 岡山医学会
File Version publisher
DOI 10.4044/joma.136.54
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Kimura, Goro| Yamada, Haruto| Takata, Ichiro| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Tsukahara, Kohei| Aokage, Toshiyuki| Hagiya, Hideharu| Toyooka, Shinichi| Tsukahara, Hirokazu| Maeda, Yoshinobu|
Keywords novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
Published Date 2024-07-31
Publication Title International Journal of Molecular Sciences
Volume volume25
Issue issue15
Publisher MDPI
Start Page 8370
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39125944
DOI 10.3390/ijms25158370
Web of Science KeyUT 001286890700001
Related Url isVersionOf https://doi.org/10.3390/ijms25158370
FullText URL fulltext.pdf
Author Notomi, Ryotaro| Sasaki, Shigeki| Taniguchi, Yosuke|
Published Date 2024-07-31
Publication Title RSC Chemical Biology
Volume volume5
Issue issue9
Publisher Royal Society of Chemistry
Start Page 884
End Page 890
ISSN 2633-0679
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 39211471
DOI 10.1039/d4cb00134f
Web of Science KeyUT 001280542000001
Related Url isVersionOf https://doi.org/10.1039/d4cb00134f
FullText URL fulltext20240804-01.pdf
Author Kawana, Shinichi| Sugimoto, Seiichiro| Matsubara, Kei| Choshi, Haruki| Tanaka, Shin| Ishihara, Megumi| Habu, Tomohiro| Hashimoto, Kohei| Suzawa, Ken| Shien, Kazuhiko| Miyoshi, Kentaroh| Okazaki, Mikio| Nakayama, Masanori| Toyooka, Shinichi|
Keywords Adverse events COVID-19 Immunogenicity Lung transplantation mRNA vaccine
Note © 2024 The Japanese Respiratory Society. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jul. 2025.|
Published Date 2024-09
Publication Title Respiratory Investigation
Volume volume62
Issue issue5
Publisher Elsevier BV
Start Page 804
End Page 810
ISSN 2212-5345
NCID AA12579673
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Japanese Respiratory Society.
File Version author
PubMed ID 39002293
DOI 10.1016/j.resinv.2024.07.004
Web of Science KeyUT 001270304600001
Related Url isVersionOf https://doi.org/10.1016/j.resinv.2024.07.004