Conditions

close

result 474 件

FullText URL fulltext.pdf
Author Manabe, Kenta| Shien, Kazuhiko| Furukawa, Shinichi| Seno, Tomoya| Ishimura, Kousei| Tanaka, Shin| Suzawa, Ken| Okazaki, Mikio| Sugimoto, Seiichiro| Toyooka, Shinichi|
Keywords Osimertinib Lung cancer Interstitial lung disease Pulmonary embolism
Published Date 2025-07-03
Publication Title BMC Pulmonary Medicine
Volume volume25
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 311
ISSN 1471-2466
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 40610986
DOI 10.1186/s12890-025-03787-7
Related Url isVersionOf https://doi.org/10.1186/s12890-025-03787-7
FullText URL fulltext.pdf
Author Tsukioki, Takahiro| Takata, Nozomu| Dennis, Saya R.| Terata, Kaori| Sagara, Yasuaki| Sakai, Takehiko| Takayama, Shin| Kitagawa, Dai| Kikawa, Yuichiro| Takahashi, Yuko| Iwatani, Tsuguo| Hara, Fumikata| Fujisawa, Tomomi| Shien, Tadahiko|
Keywords Breast cancer FACT-B FACT-B+4 QOL
Note The version of record of this article, first published in Breast Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12282-025-01701-x|
Published Date 2025-05-08
Publication Title Breast Cancer
Volume volume32
Issue issue4
Publisher Springer Science and Business Media LLC
Start Page 773
End Page 782
ISSN 1340-6868
NCID AA1103354X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40338515
DOI 10.1007/s12282-025-01701-x
Web of Science KeyUT 001483857300001
Related Url isVersionOf https://doi.org/10.1007/s12282-025-01701-x
FullText URL fulltext.pdf
Author OTANI, YUSUKE| MAEKAWA, MASAKI| TANAKA, ATSUSHI| PEÑA, TIRSO| CHIN, VANESSA D.| ROGACHEVSKAYA, ANNA| TOYOOKA, SHINICHI| ROEHRL, MICHAEL H.| FUJIMURA, ATSUSHI|
Keywords C1orf50 melanoma cancer stem cells YAP/TAZ
Published Date 2025-06-26
Publication Title Cancer Genomics & Proteomics
Volume volume22
Issue issue4
Publisher International Institute of Anticancer Research
Start Page 510
End Page 524
ISSN 1109-6535
NCID AA11952487
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©2025 The Author(s).
File Version publisher
PubMed ID 40571314
DOI 10.21873/cgp.20518
Related Url isVersionOf https://doi.org/10.21873/cgp.20518
FullText URL fulltext20250507-01.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Shien, Tadahiko| Muraoka, Atsushi| Doihara, Hiroyoshi|
Keywords breast cancer chemotherapy choroidal metastasis estrogen receptor her2 immunostaining invasive ductal carcinoma ki-67 progesterone receptor radiation
Published Date 2025-05-04
Publication Title Cureus
Volume volume17
Issue issue5
Publisher Springer Science and Business Media LLC
Start Page e83484
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2025 Matsuo et al.
File Version publisher
PubMed ID 40470417
DOI 10.7759/cureus.83484
Related Url isVersionOf https://doi.org/10.7759/cureus.83484
FullText URL K0007190_abstract_review.pdf K0007190_fulltext.pdf K0007190_other.pdf K0007190_other_supplement.pdf K0007190_summary.pdf
Author NAKAMOTO, Shogo|
Published Date 2025-03-25
Content Type Thesis or Dissertation
Grant Number 甲第7190号
Granted Date 2025-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024
JaLCDOI 10.18926/AMO/68726
FullText URL 79_3_185.pdf
Author Yoshikawa, Ayumi| Taira, Naruto| Okanaga, Mayumi| Saito, Shinya|
Abstract We investigated the emotional changes that young patients with breast cancer need to undergo in order to foster relationship-building with their partners by conducting a qualitative descriptive study (March 1 to Nov. 26, 2021) and semi-structured interviews with eight postoperative patients (age 20-40 years) with breast cancer. The data were analyzed using the modified grounded theory approach (M-GTA), yielding five categories: (i) Awareness of being a breast cancer patient, (ii) Being at a loss, (iii) Support from significant others, (iv) The struggle to transition from being a patient with cancer to becoming “the person I want to be”, and (v) Reaching the “me” I want to be who can face building a relationship with a partner. These findings suggest that young breast cancer patients must feel that they can lead a normal life through activities such as work or acquiring qualifications before building relationships with their partners, and that getting closer to their desired selves is important. Nurses can provide information to young patients with breast cancer to assist them in building a solid relationship with their partners. We believe that this support may enhance the patients’ quality of life and help them achieve stronger relationships with their partners.
Keywords breast cancer patient young patient single partners relationships
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-06
Volume volume79
Issue issue3
Publisher Okayama University Medical School
Start Page 185
End Page 195
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
Author Takeda, Tatsuaki| Matsumoto, Jun| Sakai, Tomonori| Iwata, Naohiro| Hamano, Hirofumi| Koyama, Toshihiro| Ariyoshi, Noritaka| Zamami, Yoshito|
Keywords adverse event breast cancer pertuzumab trastuzumab VigiBase
Note This is the peer reviewed version of the following article: [Takeda T, Matsumoto J, Sakai T, et al. Comprehensive analysis of adverse event profile changes with pertuzumab addition to trastuzumab-based breast cancer therapy: Disproportionality analysis using VigiBase. Br J Clin Pharmacol. 2025; 1-13. doi:10.1002/bcp.70094], which has been published in final form at [https://doi.org/10.1002/bcp.70094]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in May. 2026.|
Published Date 2025-05-08
Publication Title British Journal of Clinical Pharmacology
Publisher Wiley
ISSN 0306-5251
NCID AA00574388
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 British Pharmacological Society.
File Version author
PubMed ID 40344285
DOI 10.1002/bcp.70094
Web of Science KeyUT 001483932800001
Related Url isVersionOf https://doi.org/10.1002/bcp.70094
Author Ozato, Toshiki| Kono, Yoshiyasu| Horiguchi, Shigeru| Tsutsumi, Koichiro| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki|
Keywords Homologous recombination repair Small bowel adenocarcinoma Genome
Note © 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Apr. 2026.|
Published Date 2025-05-02
Publication Title European Journal of Cancer
Volume volume220
Publisher Elsevier BV
Start Page 115401
ISSN 0959-8049
NCID AA1075407X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Elsevier Ltd.
File Version author
PubMed ID 40188744
DOI 10.1016/j.ejca.2025.115401
Web of Science KeyUT 001465491700001
Related Url isVersionOf https://doi.org/10.1016/j.ejca.2025.115401
FullText URL fulltext.pdf
Author Kamio, Tomohiro| Kono, Yoshiyasu| Hirosuna, Kensuke| Ozato, Toshiki| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki|
Keywords comprehensive genomic profiling early-onset gastric cancer oxaliplatin TP53
Published Date 2025-04-18
Publication Title Cancer Medicine
Volume volume14
Issue issue8
Publisher Wiley
Start Page e70793
ISSN 2045-7634
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40249206
DOI 10.1002/cam4.70793
Web of Science KeyUT 001469550900001
Related Url isVersionOf https://doi.org/10.1002/cam4.70793
JaLCDOI 10.18926/AMO/68648
FullText URL 79_2_101.pdf
Author Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka|
Abstract To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes.
Keywords breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 101
End Page 107
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40302281
Web of Science KeyUT 001485544200005
FullText URL fulltext.pdf
Author Tanaka, Shin| Nakata, Eiji| Ryuko, Tsuyoshi| Itano, Takuto| Tomioka, Yasuaki| Shien, Kazuhiko| Suzawa, Ken| Miyoshi, Kentaroh| Okazaki, Mikio| Sugimoto, Seiichiro| Ozaki, Toshifumi| Toyooka, Shinichi|
Keywords Primary chest wall sarcomas Chest wall resection Chondrosarcoma Robust chest wall reconstruction
Published Date 2025-04-01
Publication Title European Journal of Orthopaedic Surgery & Traumatology
Volume volume35
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 141
ISSN 1432-1068
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40167819
DOI 10.1007/s00590-025-04260-1
Web of Science KeyUT 001459451400002
Related Url isVersionOf https://doi.org/10.1007/s00590-025-04260-1
FullText URL fulltext.pdf
Author Al-Hammad, Wlla E.| Kuroda, Masahiro| Al Jamal, Jamal, Ghaida| Fujikura, Mamiko| Kamizaki, Ryo| Kuroda, Kazuhiro| Yoshida, Suzuka| Nakamura, Yoshihide| Oita, Masataka| Tanabe, Yoshinori| Sugimoto, Kohei| Sugianto, Irfan| Barham, Majd| Tekiki, Nouha| Hisatomi, Miki| Asaumi, Junichi|
Keywords breast cancer radiation therapy heart dose cut-off value machine learning robustness instability F2 score deep inspiration breath-hold technique computed tomography
Published Date 2025-03-10
Publication Title Diagnostics
Volume volume15
Issue issue6
Publisher MDPI
Start Page 668
ISSN 2075-4418
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
PubMed ID 40150011
DOI 10.3390/diagnostics15060668
Web of Science KeyUT 001452220400001
Related Url isVersionOf https://doi.org/10.3390/diagnostics15060668
Author Ninomiya, Toshifumi| Kemmotsu, Naoya| Mukohara, Fumiaki| Magari, Masaki| Miyamoto, Ai| Ueda, Youki| Ishino, Takamasa| Nagasaki, Joji| Fujiwara, Tomohiro| Yamamoto, Hidetaka| Hayashi, Hidetoshi| Tachibana, Kota| Ishida, Joji| Otani, Yoshihiro| Tanaka, Shota| Toyooka, Shinichi| Okamoto, Isamu| Togashi, Yosuke|
Note This is an Accepted Manuscript of an article published by American Association for Cancer Research (AACR).| This fulltext file will be available in Mar. 2026.|
Published Date 2025-03-14
Publication Title Cancer Research
Volume volume85
Issue issue6
Publisher American Association for Cancer Research (AACR)
Start Page 1082
End Page 1096
ISSN 0008-5472
NCID AA00598557
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©2025 American Association for Cancer Research
File Version author
PubMed ID 39804971
DOI 10.1158/0008-5472.can-24-2274
Web of Science KeyUT 001444866400013
Related Url isVersionOf https://doi.org/10.1158/0008-5472.can-24-2274
FullText URL fulltext.pdf
Author Tanaka, Shin| Umeda, Masashi| Ujike, Hiroyuki| Ryuko, Tsuyoshi| Tomioka, Yasuaki| Miyoshi, Kentaroh| Okazaki, Mikio| Sugimoto, Seiichiro| Toyooka, Shinichi|
Keywords Lung preservation Donation after circulatory death Abdominal normothermic regional perfusion
Note The version of record of this article, first published in General Thoracic and Cardiovascular Surgery, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11748-025-02137-y|
Published Date 2025-03-16
Publication Title General Thoracic and Cardiovascular Surgery
Publisher Springer Science and Business Media LLC
ISSN 1863-6705
NCID AA12201344
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40089938
DOI 10.1007/s11748-025-02137-y
Web of Science KeyUT 001446042300001
Related Url isVersionOf https://doi.org/10.1007/s11748-025-02137-y
Author Maruyama, Masato| Torii, Reiya| Matsui, Hazuki| Hayashi, Hiroki| Ogawara, Ken-ichi| Higaki, Kazutaka|
Keywords Drug delivery Vascular normalization Breast cancer Liposome Cancer-associated fibroblast
Note © 2025 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Feb. 2026.|
Published Date 2025-04
Publication Title European Journal of Pharmaceutics and Biopharmaceutics
Volume volume209
Publisher Elsevier BV
Start Page 114663
ISSN 0939-6411
NCID AA10836618
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Elsevier B.V.
File Version author
PubMed ID 39922508
DOI 10.1016/j.ejpb.2025.114663
Web of Science KeyUT 001427462000001
Related Url isVersionOf https://doi.org/10.1016/j.ejpb.2025.114663
JaLCDOI 10.18926/AMO/68362
FullText URL 79_1_051.pdf
Author Miura, Taro| Kawasaki, Yoichi| Hamano, Hirofumi| Zamami, Yoshito| Sendo, Toshiaki|
Abstract Photoinitiators are used in the manufacture of many daily products, and may produce harmful effects due to their cytotoxicity. They have also been detected in human serum. Here, we investigated the histamine-producing effects in HMC-1 cells and the inflammatory cytokine release effects in RAW264 cells for four photoinitiators: 1-hydroxycyclohexyl phenyl ketone; 2-isopropylthioxanthone; methyl 2-benzoylbenzoate; and 2-methyl-4´-(methylthio)-2-morpholinopropiophenone. All four promoted histamine production in HMC-1 cells; however, they did not significantly affect the release of inflammatory cytokines in RAW264 cells. These findings suggest that these four photoinitiators induce inflammatory cytokine-independent histamine production, potentially contributing to histamine-mediated chronic inflammation in vitro.
Keywords photoinitiator ink injection histamine inflammation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 51
End Page 58
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012160
Web of Science KeyUT 001440463800007
JaLCDOI 10.18926/AMO/68354
FullText URL 79_1_009.pdf
Author Ikeya, Nanami| Okita, Atsushi| Hashida, Shinsuke| Yamamoto, Sumiharu| Ikeda, Hirokuni| Tsukuda, Kazunori| Toyooka, Shinichi|
Abstract Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy.
Keywords sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-02
Volume volume79
Issue issue1
Publisher Okayama University Medical School
Start Page 9
End Page 19
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40012155
Web of Science KeyUT 001440463800002
FullText URL fulltext20250213-02.pdf suppl20250213-02.pdf
Author Mukohara, Fumiaki| Iwata, Kazuma| Ishino, Takamasa| Inozume, Takashi| Nagasaki, Joji| Ueda, Youki| Suzawa, Ken| Ueno, Toshihide| Ikeda, Hideki| Kawase, Katsushige| Saeki, Yuka| Kawashima, Shusuke| Yamashita, Kazuo| Kawahara, Yu| Nakamura, Yasuhiro| Honobe-Tabuchi, Akiko| Watanabe, Hiroko| Dansako, Hiromichi| Kawamura, Tatsuyoshi| Suzuki, Yutaka| Honda, Hiroaki| Mano, Hiroyuki| Toyooka, Shinichi| Kawazu, Masahito| Togashi, Yosuke|
Keywords cancer immunology somatic mutation T cell tumor-infiltrating lymphocytes
Note This is an Accepted Manuscript of an article published by Proceedings of the National Academy of Sciences.| This fulltext file will be available in Feb. 2025.|
Published Date 2024-08-21
Publication Title Proceedings of the National Academy of Sciences
Volume volume121
Issue issue35
Publisher Proceedings of the National Academy of Sciences
Start Page e2320189121
ISSN 0027-8424
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 the Author(s).
File Version author
PubMed ID 39167601
DOI 10.1073/pnas.2320189121
Web of Science KeyUT 001408603100001
Related Url isVersionOf https://doi.org/10.1073/pnas.2320189121
FullText URL fulltext.pdf
Author Yamada, Yuto| Fujiwara, Masaki| Nakaya, Naoki| Otsuki, Koji| Shimazu, Taichi| Fujimori, Maiko| Hinotsu, Shiro| Nagoshi, Kiwamu| Uchitomi, Yosuke| Inagaki, Masatoshi|
Keywords bipolar disorder cancer screening COVID-19 healthcare disparities schizophrenia
Published Date 2025-02-02
Publication Title Psychiatry and Clinical Neurosciences Reports
Volume volume4
Issue issue1
Publisher Wiley
Start Page e70062
ISSN 2769-2558
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 39902101
DOI 10.1002/pcn5.70062
Web of Science KeyUT 001410823100001
Related Url isVersionOf https://doi.org/10.1002/pcn5.70062
FullText URL fulltext.pdf
Author Kuribayashi, Tadahiro| Kinoshita, Rie| Ninomiya, Kiichiro| Makimoto, Go| Kubo, Toshio| Rai, Kammei| Ichihara, Eiki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki| Toyooka, Shinichi| Sakaguchi, Masakiyo| Ohashi, Kadoaki|
Keywords S100A8/A9 Lung cancer Immune checkpoint inhibitors
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-025-87232-z|
Published Date 2025-01-20
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 2577
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 39833332
DOI 10.1038/s41598-025-87232-z
Web of Science KeyUT 001400880600002
Related Url isVersionOf https://doi.org/10.1038/s41598-025-87232-z