result 705 件
FullText URL | fulltext20211011-1.pdf figures20211011-1.pdf |
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Author | Uchida, Tetsuya| Onishi, Yukihisa| Goto, Atsu| |
Keywords | rigid polymer network heat resistance proton phosphoric acid conductivity |
Note | This is the peer reviewed version of the following article: [Uchida, T, Onishi, Y, Goto, A. Preparation of highly porous heat-resistant polybenzoxazole network films and their electrical conductivities. Polym Adv Technol. 2021; 1- 7. doi:10.1002/pat.5494], which has been published in final form at [https://doi.org/10.1002/pat.5494]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-ArchivedVersions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wileyor by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked toWiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof bythird parties from platforms, services and websites other than Wiley Online Library must be prohibited. This fulltext is available in Sep. 2022.| |
Published Date | 2021-9-9 |
Publication Title | Polymers for Advanced Technologies |
Publisher | Wiley |
Start Page | 1 |
ISSN | 1042-7147 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
DOI | 10.1002/pat.5494 |
Web of Science KeyUT | 000695527000001 |
Related Url | isVersionOf https://doi.org/10.1002/pat.5494 |
FullText URL | fulltext20211006-2a.pdf |
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Author | Kamada, Yasuhiko| Kusumoto, Rie| Kashino, Chiaki| Kubo, Kotaro| Mitsui, Takashi| Masuyama, Hisashi| |
Keywords | double cross plasty genital chronic graft-versus-host disease hematocolpos hematopoietic stem cell transplantation vaginal reconstruction |
Note | This is the peer reviewed version of the following article: [Kamada, Y., Kusumoto, R., Kashino, C., Kubo, K., Mitsui, T., & Masuyama, H. (2021). Surgically treated genital chronic graft‐versus‐host disease in women: A report of three cases. Journal of Obstetrics and Gynaecology Research.], which has been published in final form at [https://doi.org/10.1111/jog.15005]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-ArchivedVersions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wileyor by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked toWiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof bythird parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
Published Date | 2021-09-05 |
Publication Title | Journal of Obstetrics and Gynaecology Research |
Volume | volume47 |
Issue | issue11 |
Publisher | Wiley |
Start Page | 4122 |
End Page | 4126 |
ISSN | 1341-8076 |
NCID | AA11082002 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Japan Society of Obstetrics and Gynecology |
File Version | author |
PubMed ID | 34482585 |
DOI | 10.1111/jog.15005 |
Web of Science KeyUT | 000697443000001 |
Related Url | isVersionOf https://doi.org/10.1111/jog.15005 |
FullText URL | fulltext.pdf |
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Author | Sato, Ryoichi| Kodera, Yuta| Ali, Md. Arshad| Kusaka, Takuya| Nogami, Yasuyuki| Morelos-Zaragoza, Robert H.| |
Keywords | entropy field programmable gate array true random number generator period ring oscillator stomatic process state transition XOR gate |
Published Date | 2021-09-05 |
Publication Title | Entropy |
Volume | volume23 |
Issue | issue9 |
Publisher | MDPI |
Start Page | 1168 |
ISSN | 1099-4300 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 by the authors. |
File Version | publisher |
PubMed ID | 34573793 |
DOI | 10.3390/e23091168 |
Web of Science KeyUT | 000699789000001 |
Related Url | isVersionOf https://doi.org/10.3390/e23091168 |
FullText URL | fulltext.pdf |
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Author | Mansour, Hager| Hassan, Ghmkin| Afify, Said M.| Yan, Ting| Seno, Akimasa| Seno, Masaharu| |
Keywords | metastasis cancer stem cells transplantation surgery |
Published Date | 2020-08-21 |
Publication Title | Methods and Protocols |
Volume | volume3 |
Issue | issue3 |
Publisher | MDPI |
Start Page | 60 |
ISSN | 2409-9279 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32825540 |
DOI | 10.3390/mps3030060 |
Web of Science KeyUT | 000698975500015 |
Related Url | isVersionOf https://doi.org/10.3390/mps3030060 |
FullText URL | fulltext20210928-1.pdf |
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Author | Umeda, Yuzo| Mitsuhashi, Toshiharu| Kojima, Toru| Satoh, Daisuke| Sui, Kenta| Endo, Yoshikatsu| Inagaki, Masaru| Oishi, Masahiro| Yagi, Takahito| Fujiwara, Toshiyoshi| |
Keywords | intrahepatic cholangiocarcinoma lymph node excision multicenter study propensity score retrospective studies |
Note | This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.| |
Published Date | 2021-9-16 |
Publication Title | Journal of Hepato-Biliary-Pancreatic Sciences |
Publisher | Wiley |
Start Page | 1 |
End Page | 13 |
ISSN | 1868-6974 |
NCID | AA12507209 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Authors. Journal of Hepato-Biliary-Pancreatic Sciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Hepato-Biliary-Pancreatic Surgery. |
File Version | publisher |
PubMed ID | 34473411 |
DOI | 10.1002/jhbp.1038 |
Web of Science KeyUT | 000696321700001 |
Related Url | isVersionOf https://doi.org/10.1002/jhbp.1038 |
FullText URL | fulltext.pdf |
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Author | Matsumoto, Ryohtaroh| Takahashi, Daisuke| Watanabe, Masaki| Nakatani, Shunsuke| Takamura, Yuta| Kurosaki, Yuji| Kakuta, Hiroki| Hase, Koji| |
Keywords | RXR NEt-3IB inflammatory bowel disease colitis Th1 cells |
Published Date | 2021-08-12 |
Publication Title | Frontiers In Pharmacology |
Volume | volume12 |
Publisher | Frontiers Media SA |
Start Page | 715752 |
ISSN | 1663-9812 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Matsumoto, Takahashi, Watanabe, Nakatani, Takamura,Kurosaki, Kakuta and Hase. |
File Version | publisher |
PubMed ID | 34475823 |
DOI | 10.3389/fphar.2021.715752 |
Web of Science KeyUT | 000693889000001 |
Related Url | isVersionOf https://doi.org/10.3389/fphar.2021.715752 |
JaLCDOI | 10.18926/AMO/62397 |
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FullText URL | 75_4_455.pdf |
Author | Muraoka, Sosuke| Yamane, Kentaro| Misawa, Haruo| Takigawa, Tomoyuki| Tetsunaga, Tomoko| Oda, Yoshiaki| Nakanishi, Kazuo| Ozaki, Toshifumi| Tanaka, Takehiro| |
Abstract | The intraoperative pathological diagnosis (IPD) plays an important role in determining the optimal surgical treatment for spinal cord tumors. The final pathological diagnosis (FPD) is sometimes different from the IPD. Here, we sought to identify the accuracy of the IPD of spinal cord tumors compared to the FPD. We retrospec-tively analyzed the cases of 108 patients with spinal cord tumors treated surgically in our institute; the IPD, FPD, mismatched cases, and concordance rate between the IPD and FPD were investigated. Five cases involved a mismatch between the IPD and FPD. The overall concordance rate was 95.4%, with 90.9% for extra-dural lesions, 98.5% for intradural extramedullary lesions, 84.2% for intramedullary lesions, and 100% for dumbbell-type tumors. The concordance rate of intramedullary lesions tended to be lower than that of other lesions (p = 0.096). A lower concordance rate was revealed for intramedullary lesions compared to the other lesions. Despite the IPD clearly remaining a valuable tool during operative procedures, surgeons should recog-nize the limitations of IPDs and make comprehensive decisions about surgical treatments. |
Keywords | spinal cord tumor intraoperative pathological diagnosis final pathological diagnosis concordance rate |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-08 |
Volume | volume75 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 455 |
End Page | 460 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34511612 |
Web of Science KeyUT | 000697944600007 |
NAID | 120007146040 |
JaLCDOI | 10.18926/AMO/62380 |
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FullText URL | 75_4_423.pdf |
Author | Takihira, Shota| Furumatsu, Takayuki| Okazaki, Yuki| Hiranaka, Takaaki| Kintaka, Keisuke| Kodama, Yuya| Kamatsuki, Yusuke| Miyazawa, Shinichi| Ozaki, Toshifumi | |
Abstract | The treatment of medial meniscus posterior root tears (MMPRTs) has evolved to include a variety of repair strategies. This study investigated the location of the articular cartilage degeneration during second-look arthroscopy after transtibial pullout repair with a modified Mason-Allen suture using FasT-Fix (F-MMA) in 22 patients with MMPRTs. Second-look arthroscopy was performed approximately 1 year postoperatively to eval-uate the healing status of the medial meniscus (MM). Articular cartilage degeneration was assessed using the International Cartilage Repair Society grade at primary surgery and again at second-look arthroscopy. Articular surfaces of the medial/lateral femoral condyles, the medial/lateral tibial plateaus, the patella and the trochlea were divided into several subcompartments (MF 1-9, LF 1-9, MT 1-5, LT 1-5, P 1-9, T 1-3). Clinical evaluations used the Japanese Knee Injury and Osteoarthritis Outcome, Lysholm, and International Knee Documentation Committee scores. Second-look arthroscopic findings showed complete healing of the MM posterior root in all patients. Significant differences between pullout repair and second-look arthroscopy were observed for MF 2 and 4, LF 7, and P 7. All clinical outcomes were improved. Our results indicate that this technique improves clinical outcomes postoperatively and may prevent the progression of cartilage degenera-tion on the loading surface of the medial knee compartment. |
Keywords | articular cartilage medial meniscus modified Mason-Allen suture technique posterior root tear second-look arthroscopy |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-08 |
Volume | volume75 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 423 |
End Page | 430 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34511608 |
Web of Science KeyUT | 000697944600003 |
NAID | 120007146061 |
JaLCDOI | 10.18926/AMO/62378 |
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FullText URL | 75_4_403.pdf |
Author | Matoba, Ryo| Morizane, Yuki| |
Abstract | Epiretinal membrane (ERM) is a common retinal disease characterized by cellular proliferation and metaplasia that lead to the formation of a pathological fibrocellular membrane immediately superjacent to the inner retinal surface. The vast majority of ERMs are considered idiopathic. However, ERM formation can result from various primary intraocular diseases, including retinal breaks and detachment, retinal vascular diseases, and vitreoretinal inflammatory conditions. Although ERMs are generally asymptomatic or cause mild metamorphopsia and/or a modest decrease in visual acuity, some can cause severe macular distortion and macular edema, resulting in significantly impaired function. Surgical removal of ERM is the only treatment, and improvements in vitrectomy systems have enabled less invasive treatment. However, there are currently no standardized criteria for ERM surgery, and the indications for surgery are determined from the patient’s subjective symptoms. Another problem with ERM surgery is that not all patients show satisfactory postoperative recovery of visual function. Thus, further research is needed to determine the criteria for ERM surgery and methods to improve the postoperative prognosis. |
Keywords | epiretinal membrane vitrectomy optical coherence tomography internal limiting membrane lamellar macular hole |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2021-08 |
Volume | volume75 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 403 |
End Page | 413 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34511606 |
Web of Science KeyUT | 000697944600001 |
NAID | 120007146059 |
FullText URL | fulltext20210824-2.pdf |
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Author | Yang, Jiajia| Huber, Laurentius| Yu, Yinghua| Bandettini, Peter A.| |
Keywords | Cortical layers Laminar fMRI Cortical circuit models Human brain function Cognition |
Note | This is an open access article under the CC BY-NC-ND license.| |
Published Date | 2021-9 |
Publication Title | Neuroscience & Biobehavioral Reviews |
Volume | volume128 |
Publisher | Elsevier BV |
Start Page | 467 |
End Page | 478 |
ISSN | 0149-7634 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Author(s). |
File Version | publisher |
PubMed ID | 34245758 |
DOI | 10.1016/j.neubiorev.2021.07.005 |
Web of Science KeyUT | 000679529700001 |
Related Url | isVersionOf https://doi.org/10.1016/j.neubiorev.2021.07.005 |
FullText URL | fulltext20210811-1.pdf |
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Author | Miyatake, Takahisa| |
Keywords | Zeugodacus cucurbitae mass-rearing mating melon fly quality 16 control sterile insect technique SIT Diptera Tephritidae correlated responses |
Note | This is the peer reviewed version of the following article: [Miyatake, T. (2021), Selection for age at reproduction changes pre-mating period and mating frequency in Zeugodacus cucurbitae: impacts on insect quality control. Entomol Exp Appl, 169: 959-965.], which has been published in final form at [https://doi.org/10.1111/eea.13084]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
Published Date | 2021-7-5 |
Publication Title | Entomologia Experimentalis et Applicata |
Volume | volume169 |
Publisher | Wiley |
Start Page | 959 |
End Page | 965 |
ISSN | 0013-8703 |
NCID | AA00636634 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Netherlands Entomological Society Entomologia Experimentalis et Applicata 1–7, 2021 |
File Version | author |
DOI | 10.1111/eea.13084 |
Web of Science KeyUT | 000678839700001 |
Related Url | isVersionOf https://doi.org/10.1111/eea.13084 |
FullText URL | fulltext20210721-3.pdf |
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Author | Doi, Toshihisa| |
Note | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10209-021-00827-x| |
Published Date | 2021-7-8 |
Publication Title | Universal Access in the Information Society |
Volume | volume22 |
Issue | issue1 |
Publisher | Springer Science and Business Media LLC |
Start Page | 111 |
End Page | 119 |
ISSN | 1615-5289 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
DOI | 10.1007/s10209-021-00827-x |
Web of Science KeyUT | 000670833700001 |
Related Url | isVersionOf https://doi.org/10.1007/s10209-021-00827-x |
FullText URL | fulltext.pdf |
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Author | Tahjib-Ul-Arif, Md.| Zahan, Mst, Ishrat| Karim, Md. Masudul| Imran, Shahin| Hunter, Charles T.| Islam, Md. Saiful| Mia, Md. Ashik| Hannan, Md. Abdul| Rhaman, Mohammad Saidur| Hossain, Md. Afzal| Brestic, Marian| Skalicky, Milan| Murata, Yoshiyuki| |
Keywords | citrate heavy metal stress drought stress antioxidant reactive oxygen species salinity aluminum toxicity |
Published Date | 2021-07-05 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume22 |
Issue | issue13 |
Publisher | MDPI |
Start Page | 7235 |
ISSN | 1422-0067 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 by the authors. |
File Version | publisher |
DOI | 10.3390/ijms22137235 |
Web of Science KeyUT | 000671283500001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms22137235 |
FullText URL | fulltext.pdf |
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Author | Nakamura, Makoto| Meguri, Yusuke| Ikegawa, Shuntaro| Kondo, Takumi| Sumii, Yuichi| Fukumi, Takuya| Iwamoto, Miki| Sando, Yasuhisa| Sugiura, Hiroyuki| Asada, Noboru| Ennishi, Daisuke| Tomida, Shuta| Fukuda-Kawaguchi, Emi| Ishii, Yasuyuki| Maeda, Yoshinobu| Matsuoka, Ken-Ichi| |
Published Date | 2021-06-23 |
Publication Title | Scientific Reports |
Volume | volume11 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 13125 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021 |
File Version | publisher |
PubMed ID | 34162921 |
DOI | 10.1038/s41598-021-92526-z |
Web of Science KeyUT | 000669995600012 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-021-92526-z |
FullText URL | fulltext.pdf |
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Author | Sakaida, Kyosuke| Omori, Kazuhiro| Nakayama, Masaaki| Mandai, Hiroki| Nakagawa, Saki| Sako, Hidefumi| Kamei, Chiaki| Yamamoto, Satoshi| Kobayashi, Hiroya| Ishii, Satoki| Ono, Mitsuaki| Ibaragi, Soichiro| Yamashiro, Keisuke| Yamamoto, Tadashi| Suga, Seiji| Takashiba, Shogo| |
Keywords | (+)-terrein ovariectomy osteoporosis RANKL PKC |
Published Date | 2021-06-08 |
Publication Title | Frontiers In Pharmacology |
Volume | volume12 |
Publisher | Frontiers Media SA |
Start Page | 674366 |
ISSN | 1663-9812 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Sakaida, Omori, Nakayama, Mandai, Nakagawa, Sako, Kamei, Yamamoto, Kobayashi, Ishii, Ono, Ibaragi, Yamashiro, Yamamoto, Suga and Takashiba. |
File Version | publisher |
PubMed ID | 34168561 |
DOI | 10.3389/fphar.2021.674366 |
Web of Science KeyUT | 000664090900001 |
Related Url | isVersionOf https://doi.org/10.3389/fphar.2021.674366 |
FullText URL | fulltext.pdf |
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Author | Kageyama, Misaki| Hagiya, Hideharu| Ueda, Yasutaka| Ohtani, Katsuki| Fukumori, Yasuo| Inoue, Norimitsu| Wakamiya, Nobutaka| Yoneda, Nanoka| Kimura, Keigo| Nagasawa, Motonori| Nakagami, Futoshi| Nishi, Isao| Sugimoto, Ken| Rakugi, Hiromi| |
Keywords | complement addition test complement deficiency disseminated gonococcal infection genome analysis Neisseria gonorrhoeae sexually transmitted infection |
Published Date | 2021-04-02 |
Publication Title | Medicine |
Volume | volume100 |
Issue | issue13 |
Publisher | LIPPINCOTT WILLIAMS & WILKINS |
Start Page | e25265 |
ISSN | 0025-7974 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 the Author(s). |
File Version | publisher |
PubMed ID | 33787610 |
NAID | 120007098535 |
DOI | 10.1097/MD.0000000000025265 |
Web of Science KeyUT | 000658960700045 |
Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000025265 |
JaLCDOI | 10.18926/AMO/62233 |
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FullText URL | 75_3_373.pdf |
Author | Yaylali, Guzin F.| Dedeoglu, Ozen | Topsakal, Senay| Herek, Duygu| Senol, Hande| |
Abstract | Osteocalcin (OC) is inversely related to body fat distribution and fasting glucose levels. We sought to observe the effect of OC on fat distribution and subclinical atherosclerosis as measured by carotid intima-media thickness (CIMT) in premenopausal obese women. In this prospective observational study, totally, 73 premenopausal obese women (aged 17-55 years) and 53 healthy women (aged 20-50 years) with normal weight were included as controls. Anthropometric measurements, total fat and fat ratio, insulin, fasting blood glucose, and OC levels were estimated. Ultrasonography was used to assess fat distribution, and fat thickness was measured in 4 regions. Subcutaneous fat (SCF), visceral fat (VF), and preperitoneal fat (PPF) thicknesses were considerably higher in obese subjects (p<0.01) than healthy controls, while OC levels were significantly lower. No correlation was observed between OC levels and SCF, VF, or PPF. In a multiple regression analysis, OC was significantly positively associated with SCF (p=0.04, Beta=0.284). No associations were observed between OC levels and VF, PPF, or CIMT. A significant association was observed between parathyroid hormone (PTH) and VF (p=0.021, Beta=0.284), and vitamin D levels were inversely associated with VF (p=0.002, r=−0.366). OC levels were lower in premenopausal obese women than normal-weight healthy controls, but OC exhibited no correlation with VF or PPF, and only a weak positive association with SCF. Additionally, VF was positively correlated with PTH and inversely correlated with vitamin D. These results suggest that OC may be an early indicator of lipid accumulation in te subcutaneous area and development of atherosclerosis. |
Keywords | body fat composition carotid intima-media thickness obesity osteocalcin premenopausal women |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-06 |
Volume | volume75 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 373 |
End Page | 379 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34176942 |
Web of Science KeyUT | 000667147700013 |
NAID | 120007089830 |
JaLCDOI | 10.18926/AMO/62230 |
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FullText URL | 75_3_351.pdf |
Author | Mitamura, Katsuya| Norikane, Takashi| Yamamoto, Yuka| Ihara-Nishishita, Ayumi| Kobata, Takuya| Fujimoto, Kengo| Takami, Yasukage| Kudomi, Nobuyuki| Hoshikawa, Hiroshi| Nishiyama, Yoshihiro| |
Abstract | We assessed the role of 18F-FDG PET/CT texture indices for the differentiation of squamous cell carcinoma (SCC) and non-Hodgkin’s lymphoma (NHL) in the oropharynx. 18F-FDG PET/CT data for 27 patients with SCC and 25 patients with NHL in the oropharynx were investigated. The maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and six texture indices (homogeneity, entropy, short-run emphasis, long-run emphasis, low gray-level zone emphasis [LGZE], and high graylevel zone emphasis [HGZE]) were derived from PET images. PET/CT parameters of the SCC patients were compared with those of the NHL patients. The diagnostic accuracy of the indices for differentiating SCC from NHL was calculated by a receiver operating characteristic curve analysis. 18F-FDG uptake in the oropharynx was observed in all of the patients. The SUVmax, MTV, and TLG did not differ significantly between the SCC and NHL groups, but two of the six texture indices (LGZE [p=0.004] and HGZE [p=0.03]) showed significant differences between the groups. LGZE was the best discriminative index for the differentiation of SCC and NHL (55.6% sensitivity, 88.0% specificity). The LGZE and HGZE texture indices derived from 18F-FDG PET/CT images may be useful in differentiating SCC and NHL in the oropharynx. |
Keywords | 18F-FDG PET/CT oropharyngeal squamous cell carcinoma malignant lymphoma texture |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-06 |
Volume | volume75 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 351 |
End Page | 356 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34176939 |
Web of Science KeyUT | 000667147700010 |
NAID | 120007089827 |
JaLCDOI | 10.18926/AMO/62228 |
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FullText URL | 75_3_335.pdf |
Author | Chikuie, Nobuyuki| Hamamoto, Takao| Ueda, Tsutomu| Taruya, Takayuki| Kono, Takashi| Furuie, Hiromi| Ishino, Takashi| Takeno, Sachio| |
Abstract | Recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) has a poor prognosis. Although nivolumab is approved in Japan for treating R/MHNSCC, the response rate is low. Therefore, identifying pretreatment prognostic factors is necessary. This study assessed the utility of the neutrophil-to-lymphocyte ratio (NLR) and Glasgow Prognostic Score (GPS) as biomarkers of response to nivolumab. We retrospectively collected the data of 56 R/MHNSCC patients treated with nivolumab between May 2017 and December 2019. The Kaplan–Meier method and log-rank test were used to estimate overall survival (OS) and progression-free survival (PFS), and multivariate Cox hazard regression analysis was used to identify independent predictors of survival. Patients with a low pretreatment NLR had prolonged OS, and patients with a low pretreatment GPS had increased OS and PFS. A performance score (PS) of 0-1, development of immune-related adverse events, and GPS of 0-1 were significantly associated with OS in multivariate analysis. In summary, baseline pretreatment NLR and GPS are independently associated with OS in R/MHNSCC patients treated with nivolumab. Administration of nivolumab while maintaining the PS reflects a immune status of the host and leads to a good OS. |
Keywords | neutrophil-to-lymphocyte ratio nivolumab Glasgow Prognostic Score recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-06 |
Volume | volume75 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 335 |
End Page | 343 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34176937 |
Web of Science KeyUT | 000667147700008 |
NAID | 120007089825 |
JaLCDOI | 10.18926/AMO/62226 |
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FullText URL | 75_3_315.pdf |
Author | Wada, Riho| Fujiwara, Masaki| Yamada, Yuto| Nakaya, Naoki| Fujimori, Maiko| So, Ryuhei| Kodama, Masafumi| Higuchi, Yuji| Kakeda, Kyoko| Uchitomi, Yosuke| Yamada, Norihito| Inagaki, Masatoshi| |
Abstract | It is necessary to assess functional impairment when treating schizophrenia. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) has been adopted as a measure of functional disability in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. This study was a secondary analysis from a cross-sectional study of health-related behaviors among patients with schizophrenia. We examined the validity and reliability of the Japanese version of the 12-item WHODAS 2.0 when self-administered by such patients. Participants were 350 outpatients with schizophrenia from a psychiatric hospital. The standard six-factor structure of the WHODAS 2.0 showed a good fit for these participants. The Cronbach’s alpha coefficient was 0.858, showing good internal consistency. The WHODAS 2.0 showed moderate correlations with the modified Global Assessment of Functioning and Kessler 6 scales (r=−0.434 and 0.555, respectively). The results of this study show that the Japanese version of the 12-item self-administered WHODAS 2.0 has good internal consistency and convergent validity among patients with schizophrenia. Further exploration of the usefulness of WHODAS 2.0 in clinical settings is needed. |
Keywords | disability schizophrenia validity reliability WHODAS 2.0 |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-06 |
Volume | volume75 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 315 |
End Page | 322 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34176935 |
NAID | 120007089823 |