検索結果 - 岡山大学学術成果リポジトリ

Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells

JaLCDOI	10.18926/AMO/63425
フルテキストURL	76_2_203.pdf
著者	Masuda, Tomoya\| Tazawa, Hiroshi\| Hashimoto, Yuuri\| Ieda, Takeshi\| Kikuchi, Satoru\| Kuroda, Shinji\| Noma, Kazuhiro\| Urata, Yasuo\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
抄録	The epithelial-mesenchymal transition (EMT), a normal biological process by which epithelial cells acquire a mesenchymal phenotype, is associated with migration, metastasis, and chemoresistance in cancer cells, and with poor prognosis in patients with esophageal cancer. However, therapeutic strategies to inhibit EMT in tumor environments remain elusive. Here, we show the therapeutic potential of telomerase-specific replication- competent oncolytic adenovirus OBP-301 in human esophageal cancer TE4 and TE6 cells with an EMT phenotype. Transforming growth factor-β (TGF-β) administration induced the EMT phenotype with spindleshaped morphology, upregulation of mesenchymal markers and EMT transcription factors, migration, and chemoresistance in TE4 and TE6 cells. OBP-301 significantly inhibited the EMT phenotype via E1 accumulation. EMT cancer cells were susceptible to OBP-301 via massive autophagy induction. OBP-301 suppressed tumor growth and lymph node metastasis of TE4 cells co-inoculated with TGF-β-secreting fibroblasts. Our results suggest that OBP-301 inhibits the TGF-β-induced EMT phenotype in human esophageal cancer cells. OBP-301-mediated E1A overexpression is a promising antitumor strategy to inhibit EMT-mediated esophageal cancer progression.
キーワード	esophageal cancer EMT TGF-β oncolytic adenovirus E1A
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	203
終了ページ	215
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503449
Web of Science KeyUT	000792291900003

Structural basis for different types of hetero-tetrameric light-harvesting complexes in a diatom PSII-FCPII supercomplex

フルテキストURL	fulltext.pdf
著者	Nagao, Ryo\| Kato, Koji\| Kumazawa, Minoru\| Ifuku, Kentaro\| Yokono, Makio\| Suzuki, Takehiro\| Dohmae, Naoshi\| Akita, Fusamichi\| Akimoto, Seiji\| Miyazaki, Naoyuki\| Shen, Jian-Ren\|
発行日	2022-04-01
出版物タイトル	Nature Communications
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	1764
ISSN	2041-1723
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35365610
DOI	10.1038/s41467-022-29294-5
Web of Science KeyUT	000777408600010
関連URL	isVersionOf https://doi.org/10.1038/s41467-022-29294-5

Mapping of Nematode Resistance in Hexaploid Sweetpotato Using an Next-Generation Sequencing-Based Association Study

フルテキストURL	fulltext.pdf
著者	Obata, Nozomi\| Tabuchi, Hiroaki\| Kurihara, Miyu\| Yamamoto, Eiji\| Shirasawa, Kenta\| Monden, Yuki\|
キーワード	polyploidy nematode sweetpotato resistant cultivar breeding association study
発行日	2022-03-18
出版物タイトル	Frontiers In Plant Science
巻	13巻
出版者	Frontiers Media SA
開始ページ	858747
ISSN	1664-462X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Obata, Tabuchi, Kurihara, Yamamoto, Shirasawa and Monden.
論文のバージョン	publisher
PubMed ID	35371138
DOI	10.3389/fpls.2022.858747
Web of Science KeyUT	000778596100001
関連URL	isVersionOf https://doi.org/10.3389/fpls.2022.858747

Counterfactual Explanation of Brain Activity Classifiers Using Image-To-Image Transfer by Generative Adversarial Network

フルテキストURL	fulltext.pdf
著者	Matsui, Teppei\| Taki, Masato\| Pham, Trung Quang\| Chikazoe, Junichi\| Jimura, Koji\|
キーワード	fMRI deep learning explainable AI decoding generative neural network counterfactual explanation
発行日	2022-03-16
出版物タイトル	Frontiers In Neuroinformatics
巻	15巻
出版者	Frontiers Media
開始ページ	802938
ISSN	1662-5196
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Matsui, Taki, Pham, Chikazoe and Jimura.
論文のバージョン	publisher
PubMed ID	35369003
DOI	10.3389/fninf.2021.802938
Web of Science KeyUT	000778735900001
関連URL	isVersionOf https://doi.org/10.3389/fninf.2021.802938

Safety and Effectiveness of Perospirone in Comparison to Risperidone for Treatment of Delirium in Patients with Advanced Cancer: A Multicenter Prospective Observational Study in Real-World Psycho-Oncology Settings

JaLCDOI	10.18926/AMO/63414
フルテキストURL	76_2_195.pdf
著者	Inoue, Shinichiro\| Maeda, Isseki\| Ogawa, Asao\| Yoshiuchi, Kazuhiro\| Terada, Seishi\| Yamada, Norihito\|
抄録	The clinical benefit of perospirone for treatment of delirium in patients with advanced cancer is not sufficiently clear. The objective of this study was to compare the safety and effectiveness of perospirone to those of risperidone for the treatment of delirium in patients with advanced cancer. This is a secondary analysis of a multicenter prospective observational study in nine psycho-oncology consultation services in Japan. The study used the Delirium Rating Scale (DRS) Revised-98 to measure effectiveness and the CTCAE (Common Terminology Criteria for Adverse Events) version 4 to assess safety. Data from 16 patients who received perospirone and 53 patients who received risperidone were analyzed. The mean age was 70 years in the perospirone group and 73 years in the risperidone group. Both groups showed a significant decrease in the total score of DRS-R-98 after three days of treatment (perospirone: 11.7 (7.9-15.4) to 7.0 (3.3-10.7), difference −4.7, effect size=0.72, p=0.003; risperidone: 15.5 (13.6-17.4) to 12.2 (10.1-14.2), difference −3.3, effect size=0.55, p=0.00). The risperidone group showed significant improvements in sleep-wake cycle disturbance, orientation, attention, and visuospatial ability. In the perospirone group, there was a significant improvement of sleep-wake cycle disturbance. The median daily dose of perospirone was 4 mg/day. There were fewer episodes of somnolence as an adverse event in the perospirone group. Low-dose perospirone was thus found to be effective for the treatment of delirium in patients with advanced cancer and may be associated with fewer episodes of over-sedation as an adverse event.
キーワード	delirium cancer perospirone risperidone
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	195
終了ページ	202
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503448
Web of Science KeyUT	000792291900002

Clinicopathological Features and Surgical Outcomes of Small Bowel Metastasis from Renal Cell Carcinoma

JaLCDOI	10.18926/AMO/63409
フルテキストURL	76_2_155.pdf
著者	Kimura, Jiro\| Okabayashi, Takehiro\| Sui, Kenta\| Tabuchi, Motoyasu\| Iwata, Jun\| Hata, Yasuhiro\| Iiyama, Tatsuo\| Ono, Noriaki\|
抄録	Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone treatment, including 1 patient from our clinic. We extracted patient characteristics, treatment, and prognostic data, resulting in clinicopathological data on 100 patients (83 men, 17 women). Mean age was 63 years (range, 16-86 years). Tumor sites were duodenum, jejunum, ileum, and multiple sites in 30, 37, 25, and 7 patients, respectively. The 1-, 3-, and 5-year overall survival rates after diagnosis were 53.0%, 36.0%, and 36.0%. Curative resection patients showed 62.1% 5-year survival after surgery, vs. 27.5% in noncurative surgical management cases. Good prognoses can be expected if these tumors are identified early for complete removal. Surgery is the only curative option. To determine the best management strategy and improve prognostic accuracy, we continue to collect and analyze epidemiological and pathological data. Although this condition is rare, surgery should be considered if curative resection is expected. Prognosis after curative resection is not poor, but recurrence is not unlikely.
キーワード	renal cell carcinoma small bowel metastasis intestine tumor
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	155
終了ページ	165
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503443
Web of Science KeyUT	000792374900007

Structure of a tetrameric photosystem I from a glaucophyte alga Cyanophora paradoxa

フルテキストURL	fulltext.pdf
著者	Kato, Koji\| Nagao, Ryo\| Ueno, Yoshifumi\| Yokono, Makio\| Suzuki, Takehiro\| Tian-Yi, Jiang\| Dohmae, Naoshi\| Akita, Fusamichi\| Akimoto, Seiji\| Miyazaki, Naoyuki\| Jian-Ren, Shen\|
発行日	2022-03-30
出版物タイトル	Nature Communications
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	1679
ISSN	2041-1723
NCID	AA12645905
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35354806
DOI	10.1038/s41467-022-29303-7
Web of Science KeyUT	000776282500020
関連URL	isVersionOf https://doi.org/10.1038/s41467-022-29303-7

Dense immobilization of gold nanoparticles onto a cotton textile for obtaining plasmonic heating

フルテキストURL	fulltext20220413-3.pdf
著者	Fukuda, Nobuko\| Ishida, Naoyuki\|
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1557/s43580-022-00262-x\|
発行日	2022-3-18
出版物タイトル	MRS Advances
巻	7巻
出版者	Springer Science and Business Media LLC
開始ページ	405
終了ページ	409
ISSN	2059-8521
NCID	AA12862506
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s), under exclusive licence to The Materials Research Society 2022
論文のバージョン	author
PubMed ID	35340397
DOI	10.1557/s43580-022-00262-x
Web of Science KeyUT	000770520400001
関連URL	isVersionOf https://doi.org/10.1557/s43580-022-00262-x

Clinicopathologic Analysis of Sinonasal Inverted Papilloma, with Focus on Human Papillomavirus Infection Status

フルテキストURL	fulltext.pdf
著者	Tsumura, Munechika\| Makihara, Seiichiro\| Nishikori, Asami\| Gion, Yuka\| Morito, Toshiaki\| Miyamoto, Shotaro\| Naito, Tomoyuki\| Uraguchi, Kensuke\| Oka, Aiko\| Tachibana, Tomoyasu\| Orita, Yorihisa\| Kariya, Shin\| Okano, Mitsuhiro\| Ando, Mizuo\| Sato, Yasuharu\|
キーワード	HPV infection sinonasal inverted papilloma diabetes mellitus young adult tumor stage
発行日	2022-02-10
出版物タイトル	Diagnostics
巻	12巻
号	2号
出版者	MDPI
開始ページ	454
ISSN	2075-4418
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35204545
DOI	10.3390/diagnostics12020454
Web of Science KeyUT	000767759900001
関連URL	isVersionOf https://doi.org/10.3390/diagnostics12020454

Advances in Superconductivity as a road to meet Energy and Health SDGs: joint Japanese and European research teams may take the lead

JaLCDOI	10.18926/63338
フルテキストURL	biess_6_148_165.pdf
著者	Kiwa, Toshihiko\| Yokoya, Takayoshi\| Chenevier, Bernard\| Cosmo, Valeria Di \| Truccato, Marco\| Sacks, William\| Sauerwein, Wolfgang\|
抄録	Based on a statistical analysis of R&D activities in the field of superconductivity (SC) in a broad sense, the paper reports that Japan's leadership is strong over the past 20 years, in terms of researchers publications and patents. It also essentially shows that among the main world players, the Japanese normalized contribution is significantly dominating, although some trend towards a diminished leadership is observed in the data over the period 2005 -present time. Finally, the paper highlights that by taking advantage of their internationally recognized expertise in the field, joint Japanese and European research teams may advance superconductivity as a reliable road to meet Energy and Health SDGs (Sustainable Development Goals -UNESCO 2015).
キーワード	Statistical review of superconductivity-related achievements energy health Okayama University and SDGs joint Japanese and European leadership in superconductivity
出版物タイトル	岡山大学全学教育・学生支援機構教育研究紀要
発行日	2021-12-30
巻	6巻
開始ページ	148
終了ページ	165
ISSN	2432-9665
言語	英語
論文のバージョン	publisher

Clinical and phenotypical characteristics of submucosal invasive carcinoma in non-ampullary duodenal cancer

フルテキストURL	fulltext.pdf
著者	Matsueda, Katsunori\| Kanzaki, Hiromitsu\| Takenaka, Ryuta\| Nakagawa, Masahiro\| Matsueda, Kazuhiro\| Iwamuro, Masaya\| Kawano, Seiji\| Kawahara, Yoshiro\| Toji, Tomohiro\| Tanaka, Takehiro\| Yagi, Takahito\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\|
発行日	2021-08-27
出版物タイトル	PLOS ONE
巻	16巻
号	8号
出版者	Public Library Science
開始ページ	e0256797
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Matsueda et al.
論文のバージョン	publisher
PubMed ID	34449813
DOI	10.1371/journal.pone.0256797
NAID	120007193739
Web of Science KeyUT	000752313300044
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0256797

Extending Treatment Intervals of R-CHOP Therapy Might Be Acceptable for Some Patients with Non-indolent Non-Hodgkin’s B-cell Lymphoma

JaLCDOI	10.18926/AMO/63204
フルテキストURL	76_1_17.pdf
著者	Fujishita, Keigo\| Yasuhisa, Sando\| Oka, Satoshi\| Fujisawa, Yuka\| Machida, Takuya\| Imai, Toshi\|
抄録	R-CHOP therapy is generally performed every 3 weeks. We investigated the effects of extending the interval of R-CHOP therapy for > 1 week on the prognoses of patients with non-indolent non-Hodgkin’s B-cell lymphoma. Among the 338 patients with non-indolent non-Hodgkin’s B-cell lymphoma who received initial chemotherapy at our institution, we focused on 178 patients who received R-CHOP therapy and analyzed the outcomes of the patients stratified by the treatment intervals. The estimated 3-year overall survival (OS) for the entire population was 82.1%. Patients treated at intervals of ≥ 4 weeks were significantly older, and they had significantly longer follow-up periods and lower relative dose intensity. But the estimated 3-year OS was comparable to those treated at <4 weeks (83.3% vs. 80.5% p=0.947). In a multivariate analysis, age and the dose of anti-cancer agents had significant impacts on OS, but there was no significant relationship regarding the treatment intervals. Propensity score matching confirmed the same result. R-CHOP therapy every around 4 weeks could achieve relatively good survival in some selected patients with non-indolent non-Hodgkin’s B-cell lymphoma.
キーワード	R-CHOP therapy relative dose intensity non-Hodgkin’s lymphoma
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-02
巻	76巻
号	1号
出版者	Okayama University Medical School
開始ページ	17
終了ページ	24
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35236994
Web of Science KeyUT	000762812700003

(Short Paper) Evidence Collection and Preservation System with Virtual Machine Monitoring

フルテキストURL	fulltext20220204-1.pdf
著者	Nakamura, Toru\| Ito, Hiroshi\| Kiyomoto, Shinsaku\| Yamauchi, Toshihiro\|
キーワード	Virtual machine introspection Forensics OS security
備考	This is the version of the book manuscript accepted for publication after peer review, but prior to copyediting and typesetting. This fulltext is available in Aug. 2023.\| IWSEC 2021: Advances in Information and Computer Security pp 64-73\|
発行日	2021-08-27
出版物タイトル	Advances in Information and Computer Security\|Lecture Notes in Computer Science
巻	12835巻
出版者	Springer International Publishing
開始ページ	64
終了ページ	73
ISSN	0302-9743
NCID	BC11247320
資料タイプ	図書
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Springer Nature Switzerland AG 2021
論文のバージョン	author
DOI	10.1007/978-3-030-85987-9_4
Web of Science KeyUT	000708084400004
関連URL	isVersionOf https://doi.org/10.1007/978-3-030-85987-9_4

Identification of MICALL2 as a Novel Prognostic Biomarker Correlating with Inflammation and T Cell Exhaustion of Kidney Renal Clear Cell Carcinoma

フルテキストURL	fulltext.pdf
著者	Lin, Wenfeng\| Chen, Wenwei\| Zhong, Jisheng\| Ueki, Hideo\| Xu, Abai\| Watanabe, Masami\| Araki, Motoo\| Liu, Chunxiao\| Nasu, Yasutomo\| Huang, Peng\|
キーワード	MICALL2 biomarker inflammation T cell exhaustion kidney renal clear cell carcinoma
発行日	2022-01-16
出版物タイトル	Journal Of Cancer
巻	13巻
号	3号
出版者	Ivyspring International Publisher
開始ページ	1214
終了ページ	1228
ISSN	1837-9664
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The author(s).
論文のバージョン	publisher
DOI	10.7150/jca.66922
Web of Science KeyUT	000746177200025
関連URL	isVersionOf https://doi.org/10.7150/jca.66922

Physical Memory Management with Two Page Sizes in Tender OS

フルテキストURL	fulltext20220201-3.pdf
著者	Kusunoki, Koki\| Yamauchi, Toshihiro\| Taniguchi, Hideo\|
抄録	Physical memory capacity has increased owing to large-scale integration. In addition, memory footprints have increased in size, as multiple programs are executed on a single computer. Many operating systems manage physical memory by paging a 4 KB page. Therefore, the number of entries in the virtual address translation table for virtual to physical increases along with the size of the memory footprints. This cause a decrease in the translation lookaside buffer (TLB) hit ratio, resulting in the performance degradation of the application. To address this problem, we propose the implementation of physical memory management with two page sizes: 4 KB and 4 MB. This allows us to expand range of addresses to be translated by a single TLB entry, thereby improving the TLB hit rate. This paper describes the design and implementation of the physical memory management mechanism that manages physical memory using two page sizes on The ENduring operating system for Distributed EnviRonment (Tender OS). Our results showed that when the page size is 4 MB, the processing time of the memory allocation can be reduced by as much as approximately 99.7%, and the processing time for process creation can be reduced by as much as approximately 51%, and the processing time of the memory operation could be reduced by as much as 91.9%.
発行日	2021-08-08
出版物タイトル	Advances in Networked-Based Information Systems\|Lecture Notes in Networks and Systems
巻	313巻
開始ページ	238
終了ページ	248
ISBN	978-3-030-84912-2
言語	英語
著作権者	© The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
論文のバージョン	author
DOI	10.1007/978-3-030-84913-9_22

Surgical technique of suprapancreatic D2 lymphadenectomy focusing on the posterior hepatic plexus for advanced gastric cancer

フルテキストURL	fulltext20220131-2.pdf
著者	Kanaya, Nobuhiko\| Kuroda, Shinji\| Kakiuchi, Yoshihiko\| Takeda, Sho\| Kikuchi, Satoru\| Noma, Kazuhiro\| Yoshida, Ryuichi\| Umeda, Yuzo\| Teraishi, Fuminori\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	Gastric cancer D2 lymphadenectomy Suprapancreatic lymphadenectomy Posterior hepatic plexus Distal gastrectomy
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00423-022-02437-4\|
発行日	2022-1-12
出版物タイトル	Langenbeck's Archives of Surgery
巻	407巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	871
終了ページ	877
ISSN	1435-2443
NCID	AA11211080
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022
論文のバージョン	author
PubMed ID	35022835
DOI	10.1007/s00423-022-02437-4
Web of Science KeyUT	000741939500003
関連URL	isVersionOf https://doi.org/10.1007/s00423-022-02437-4

Plant viruses and viroids in Japan

フルテキストURL	Fuji2022_Article_PlantVirusesAndViroidsInJapan.pdf
著者	Fuji, Shin-ichi\| Mochizuki, Tomofumi\| Okuda, Mitsuru\| Tsuda, Shinya\| Kagiwada, Satoshi\| Sekine, Ken-Taro\| Ugaki, Masashi\| Natsuaki, Keiko T.\| Isogai, Masamichi\| Maoka, Tetsuo\| Takeshita, Minoru\| Yoshikawa, Nobuyuki\| Mise, Kazuyuki\| Sasaya, Takahide\| Kondo, Hideki\| Kubota, Kenji\| Yamaji, Yasuyuki\| Iwanami, Toru\| Ohshima, Kazusato\| Kobayashi, Kappei\| Hataya, Tatsuji\| Sano, Teruo\| Suzuki, Nobuhiro\|
備考	The version of record of this article, first published in Journal of General Plant Pathology, is available online at Publisher’s website: https://doi.org/10.1007/s10327-022-01051-y\|
発行日	2022-01-17
出版物タイトル	Journal of General Plant Pathology
巻	88巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	105
終了ページ	127
ISSN	1345-2630
NCID	AA11449093
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
DOI	10.1007/s10327-022-01051-y
Web of Science KeyUT	000743461000001
関連URL	isVersionOf https://doi.org/10.1007/s10327-022-01051-y

Spred2 controls the severity of Concanavalin A-induced liver damage by limiting interferon-gamma production by CD4(+) and CD8(+) T cells

フルテキストURL	fulltext.pdf
著者	Sun, Cuiming\| Fujisawa, Masayoshi\| Ohara, Toshiaki\| Liu, Qiuying\| Cao, Chen\| Yang, Xu\| Yoshimura, Teizo\| Kunkel, Steven L.\| Matsukawa, Akihiro\|
キーワード	Liver damage MAPK Signal transduction and regulation Gene-modified mice Spred2
発行日	2022-01
出版物タイトル	Journal Of Advanced Research
巻	35巻
出版者	Elsevier
開始ページ	71
終了ページ	86
ISSN	2090-1232
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
PubMed ID	35003795
DOI	10.1016/j.jare.2021.03.014
Web of Science KeyUT	000736947300007
関連URL	isVersionOf https://doi.org/10.1016/j.jare.2021.03.014

Evaluation of nitrogen loading in the last 80 years in an urbanized Asian coastal catchment through the reconstruction of severe contamination period

フルテキストURL	fulltext.pdf
著者	Wang, Kunyang\| Onodera, Shin-Ichi\| Saito, Mitsuyo\|
キーワード	long-term nitrogen loading rapid urbanization popilation growth land use change wastewater treatment plant
発行日	2021-12-29
出版物タイトル	Environmental Research Letters
巻	17巻
号	1号
出版者	IOP Publishing Ltd
開始ページ	014010
ISSN	1748-9326
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Author(s).
論文のバージョン	publisher
DOI	10.1088/1748-9326/ac3ced
Web of Science KeyUT	000735619000001
関連URL	isVersionOf https://doi.org/10.1088/1748-9326/ac3ced

Upregulation of a nuclear factor-kappa B-interacting immune gene network in mice cochleae with age-related hearing loss

フルテキストURL	fulltext.pdf
著者	Uraguchi, Kensuke\| Maeda, Yukihide\| Takahara, Junko\| Omichi, Ryotaro\| Fujimoto, Shohei\| Kariya, Shin\| Nishizaki, Kazunori\| Ando, Mizuo\|
発行日	2021-10-22
出版物タイトル	PLOS ONE
巻	16巻
号	10号
出版者	Public Library Science
開始ページ	e0258977
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Uraguchi et al.
論文のバージョン	publisher
PubMed ID	34679122
DOI	10.1371/journal.pone.0258977
Web of Science KeyUT	000733392900043
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0258977