検索結果 749 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumoto, Namiko| Hishikawa, Nozomi| Ikegami, Ken| Sato, Kota| Omote, Yoshio| Takemoto, Mami| Yamashita, Tom| Taniguchi, Kohei| Abe, Koji| |
| キーワード | encephalopathy IgG4 related disease interleukin-6 multicentric Castleman's disease |
| 発行日 | 2021-07-01 |
| 出版物タイトル | Internal Medicine |
| 巻 | 60巻 |
| 号 | 13号 |
| 出版者 | The Japanese Society of Internal Medicine |
| 開始ページ | 2125 |
| 終了ページ | 2128 |
| ISSN | 0918-2918 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Japanese Society of Internal Medicine |
| 論文のバージョン | publisher |
| PubMed ID | 33390491 |
| DOI | 10.2169/internalmedicine.6098-20 |
| Web of Science KeyUT | 000670413600021 |
| 関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.6098-20 |
| JaLCDOI | 10.18926/AMO/62228 |
|---|---|
| フルテキストURL | 75_3_335.pdf |
| 著者 | Chikuie, Nobuyuki| Hamamoto, Takao| Ueda, Tsutomu| Taruya, Takayuki| Kono, Takashi| Furuie, Hiromi| Ishino, Takashi| Takeno, Sachio| |
| 抄録 | Recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) has a poor prognosis. Although nivolumab is approved in Japan for treating R/MHNSCC, the response rate is low. Therefore, identifying pretreatment prognostic factors is necessary. This study assessed the utility of the neutrophil-to-lymphocyte ratio (NLR) and Glasgow Prognostic Score (GPS) as biomarkers of response to nivolumab. We retrospectively collected the data of 56 R/MHNSCC patients treated with nivolumab between May 2017 and December 2019. The Kaplan–Meier method and log-rank test were used to estimate overall survival (OS) and progression-free survival (PFS), and multivariate Cox hazard regression analysis was used to identify independent predictors of survival. Patients with a low pretreatment NLR had prolonged OS, and patients with a low pretreatment GPS had increased OS and PFS. A performance score (PS) of 0-1, development of immune-related adverse events, and GPS of 0-1 were significantly associated with OS in multivariate analysis. In summary, baseline pretreatment NLR and GPS are independently associated with OS in R/MHNSCC patients treated with nivolumab. Administration of nivolumab while maintaining the PS reflects a immune status of the host and leads to a good OS. |
| キーワード | neutrophil-to-lymphocyte ratio nivolumab Glasgow Prognostic Score recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 335 |
| 終了ページ | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176937 |
| Web of Science KeyUT | 000667147700008 |
| NAID | 120007089825 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | He, Fang| Matsumoto, Yoshinori| Asano, Yosuke| Yamamura, Yuriko| Katsuyama, Takayuki| La Rose, Jose| Tomonobu, Nahoko| Komalasari, Ni Luh Gede Yoni| Sakaguchi, Masakiyo| Rottapel, Robert| Wada, Jun| |
| キーワード | ABL Abelson murine leukemia viral oncogene homolog Runx2 (runt-related transcription factor 2) tyrosine phosphorylation invasion |
| 備考 | Erratum in https://ousar.lib.okayama-u.ac.jp/62331| |
| 発行日 | 2021-05-31 |
| 出版物タイトル | Frontiers In Oncology |
| 巻 | 11巻 |
| 出版者 | Frontiers Media S.A. |
| 開始ページ | 665273 |
| ISSN | 2234-943X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 He, Matsumoto, Asano, Yamamura, Katsuyama, La Rose, Tomonobu, Komalasari, Sakaguchi, Rottapel and Wada. |
| 論文のバージョン | publisher |
| PubMed ID | 34136397 |
| DOI | 10.3389/fonc.2021.665273 |
| NAID | 120007089841 |
| Web of Science KeyUT | 000661158800001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fonc.2021.665273 |
| フルテキストURL | K0006332_abstract_review.pdf K0006332_fulltext.pdf K0006332_summary.pdf |
|---|---|
| 著者 | 松本 菜見子| |
| 発行日 | 2021-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第6332号 |
| 学位授与年月日 | 2021-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | fulltext20210602-5.pdf Supplemental_Tables20210602-5.pdf figures_all.pdf |
|---|---|
| 著者 | Fujii, Yuki| Matsumoto, Kazuyuki| Kato, Hironari| Yamazaki, Tatsuhiro| Tomoda, Takeshi| Horiguchi, Shigeru| Tsutsumi, Koichiro| Nishida, Kenji| Tanaka, Takehiro| Hanada, Keiji| Okada, Hiroyuki| |
| キーワード | Endoscopic ultrasound Subtype Intraductal papillary mucinous neoplasm |
| 備考 | © 2021 IAP and EPC. Published by Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.pan.2021.01.026] . | |
| 発行日 | 2021-4 |
| 出版物タイトル | Pancreatology |
| 巻 | 21巻 |
| 号 | 3号 |
| 出版者 | Elsevier BV |
| 開始ページ | 622 |
| 終了ページ | 629 |
| ISSN | 1424-3903 |
| NCID | AA11583711 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 33640249 |
| DOI | 10.1016/j.pan.2021.01.026 |
| Web of Science KeyUT | 000641072700016 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.pan.2021.01.026 |
| フルテキストURL | fulltext20210603-2.pdf |
|---|---|
| 著者 | Matsumoto, Jun| Kotera, Yumi| Watari, Shogo| Takeuchi, Koichi| Ueki, Hideo| Koyama, Toshihiro| Wada, Koichiro| Fujiyoshi, Masachika| Nasu, Yasutomo| Ariyoshi, Noritaka| |
| キーワード | human cytochrome P450 CYP3A renal cell carcinoma treatment outcome |
| 発行日 | 2021-5 |
| 出版物タイトル | Anticancer Research |
| 巻 | 41巻 |
| 号 | 5号 |
| 出版者 | International Institute of Anticancer Research |
| 開始ページ | 2511 |
| 終了ページ | 2521 |
| ISSN | 0250-7005 |
| NCID | AA10625860 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | Copyright © 2021 by The International Institute of Anticancer Research |
| 論文のバージョン | publisher |
| PubMed ID | 33952479 |
| DOI | 10.21873/anticanres.15029 |
| Web of Science KeyUT | 000648665800021 |
| 関連URL | isVersionOf https://doi.org/10.21873/anticanres.15029 |
| 著者 | Sakamoto, Keiji| Tomonari, Misaki| Ariya, Uyanga| Nakagiri, Erika| Matsumoto, Tetsuya| Akaji, Yasuaki| Otoda, Takashi| Hirobe, Muneto| Nachin, Baatarbileg| |
|---|---|
| キーワード | Disturbance Forest floor Salvage logging Seed source Succession |
| 備考 | metadata only access. The Version of Record is available online at: http://dx.doi.org/10.1007/s11355-021-00457-8| |
| 発行日 | 2021-04-17 |
| 出版物タイトル | Landscape and Ecological Engineering |
| 巻 | 17巻 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 267 |
| 終了ページ | 279 |
| ISSN | 1860-1871 |
| NCID | AA12090017 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | none |
| DOI | 10.1007/s11355-021-00457-8 |
| Web of Science KeyUT | 000640827800001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s11355-021-00457-8 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Asano, Yosuke| Matsumoto, Yoshinori| La Rose, Rose, Jose| He, Fang| Katsuyama, Takayuki| Ziyi, Wang| Tsuji, Shigetomo| Kamioka, Hiroshi| Rottapel, Robert| Wada, Jun| |
| 発行日 | 2021-04-19 |
| 出版物タイトル | Scientific Reports |
| 巻 | 11巻 |
| 号 | 1号 |
| 出版者 | Nature Research |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021 |
| 論文のバージョン | publisher |
| PubMed ID | 33875686 |
| DOI | 10.1038/s41598-021-87716-8 |
| NAID | 120007039923 |
| Web of Science KeyUT | 000642583500018 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-021-87716-8 |
| タイトル（別表記） | The 2019 Incentive Award of the Okayama Medical Association in Neuroscience (2019 Niimi Prize) |
|---|---|
| フルテキストURL | 133_4.pdf |
| 著者 | 河合 弘樹| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2021-04-01 |
| 巻 | 133巻 |
| 号 | 1号 |
| 開始ページ | 4 |
| 終了ページ | 6 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.133.4 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2021 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.133.4 |
| NAID | 130008034810 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yoshida, Sho| Inaba, Hiroaki| Nomura, Ryota| Murakami, Masaru| Yasuda, Hidemi| Nakano, Kazuhiko| Matsumoto-Nakano, Michiyo| |
| キーワード | Fimbriae genotypes Porphyromonas gulae silkworm larvae |
| 発行日 | 2021-01-01 |
| 出版物タイトル | Journal of ORAL Microbiology |
| 巻 | 13巻 |
| 号 | 1号 |
| 出版者 | Taylor ＆ Francis Ltd. |
| 開始ページ | 1914499 |
| ISSN | 2000-2297 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 33968314 |
| DOI | 10.1080/20002297.2021.1914499 |
| NAID | 120007037383 |
| Web of Science KeyUT | 000643754200001 |
| 関連URL | isVersionOf https://doi.org/10.1080/20002297.2021.1914499 |
| フルテキストURL | fulltext20210512_2.pdf figure20210512_2.pdf Supplemental20210512_2.pdf |
|---|---|
| 著者 | Urmi, Alam Saki| Inaba, Hiroaki| Nomura, Ryota| Yoshida, Shoko| Ohara, Naoya| Asai, Fumitoshi| Nakano, Kazuhiko| Matsumoto‐Nakano, Michiyo| |
| キーワード | coaggregation haemagglutination P. gulae protease protein degradation |
| 備考 | This is an Accepted Manuscript of an article published by Wiley. This is the peer reviewed version of the following article: [Urmi, AS, Inaba, H, Nomura, R, et al. Roles of Porphyromonas gulae proteases in bacterial and host cell biology. Cellular Microbiology. 2021; 23:e13312. https://doi.org/10.1111/cmi.13312], which has been published in final form at [https://doi.org/10.1111/cmi.13312]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| 発行日 | 2021-5-3 |
| 出版物タイトル | Cellular Microbiology |
| 出版者 | Wiley |
| 開始ページ | e13312 |
| ISSN | 1462-5814 |
| NCID | AA1136678X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 33486854 |
| DOI | 10.1111/cmi.13312 |
| Web of Science KeyUT | 000646670900001 |
| 関連URL | isVersionOf https://doi.org/10.1111/cmi.13312 |
| JaLCDOI | 10.18926/AMO/61908 |
|---|---|
| フルテキストURL | 75_2_243.pdf |
| 著者 | Tomita, Yusuke| Shimazu, Yosuke| Kawakami, Masato| Matsumoto, Hiroshi| Fujii, Kentaro| Kameda, Masahiro| Yasuhara, Takao| Suruga, Yasuki| Ota, Tomoyuki| Kimata, Yoshihiro| Kurozumi, Kazuhiko| Date, Isao| |
| 抄録 | Ventriculitis is a rare, serious complication of neurosurgery. A 59-year-old man who had undergone a craniotomy for a paranasal adenocarcinoma, developed a right frontal cystic lesion. We performed a bifrontal craniotomy to remove the lesion. The dura was repaired with non-vascularized free fascia lata in watertight fashion. Ventriculitis occurred 3 days postoperatively. Ventricular drainage, craniectomy, and endoscopic irrigation were undertaken to remove an abscess. The dura and the resection cavity were reconstructed using a vascularized anterolateral thigh adipofascial flap. His symptoms disappeared, indicating that endoscopic irrigation and reconstruction can effectively address ventriculitis even in patients in critical clinical condition. |
| キーワード | ventriculitis surgical site infection intraventricular antimicrobial therapy anterior skull base surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 243 |
| 終了ページ | 248 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953433 |
| NAID | 120007029879 |
| JaLCDOI | 10.18926/AMO/61904 |
|---|---|
| フルテキストURL | 75_2_219.pdf |
| 著者 | Sugiura, Hiroyuki| Nishimori, Hisakazu| Matsuoka, Hirofumi| Nakamura, Keiichiro| Fujii, Keiko| Fujii, Nobuharu | Matsuoka, Ken-ichi | Maeda, Yoshinobu| |
| 抄録 | Acute promyelocytic leukemia (APL) is a hematological emergency that requires urgent intervention because of the high incidence of early hemorrhagic death. When patients with APL experience a synchronous solid organ tumor, the tumor’s treatment must also be done properly. Differentiation-inducing therapy using arsenic trioxide (ATO) has less hematological toxicity compared to cytotoxic chemotherapy and might be preferable for untreated APL patients with a synchronous solid organ tumor. Here we describe the first successful case of untreated APL and synchronous endometrial cancer (in an adult Japanese woman) treated with ATO consolidation therapy and the subsequent surgery and chemotherapy for endometrial cancer. |
| キーワード | acute promyelocytic leukemia endometrial cancer arsenic trioxide synchronous multiple primary malignant tumor chemotherapy |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 219 |
| 終了ページ | 224 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953429 |
| NAID | 120007029883 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Miyawaki, Yoshia| Shimizu, Sayaka| Ogawa, Yusuke| Sada, Ken-Ei| Katayama, Yukitoshi| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Hiramatsu-Asano, Sumie| Ohashi, Keiji| Morishita, Michiko| Watanabe, Haruki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Yajima, Nobuyuki| Yoshimi, Ryusuke| Shimojima, Yasuhiro| Ohno, Shigeru| Kajiyama, Hiroshi| Ichinose, Kunihiro| Sato, Shuzo| Fujiwara, Michio| Yamazaki, Hajime| Yamamoto, Yosuke| Wada, Jun| Fukuhara, Shunichi| |
| キーワード | Systemic lupus erythematosus Glucocorticoid Emotional health Patient-reported outcome Depression Anxiety Cross-sectional study |
| 発行日 | 2021-03-10 |
| 出版物タイトル | Arthritis Research & Therapy |
| 巻 | 23巻 |
| 号 | 1号 |
| 出版者 | BMC |
| ISSN | 1478-6354 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s). 2021 |
| 論文のバージョン | publisher |
| PubMed ID | 33691746 |
| DOI | 10.1186/s13075-021-02466-2 |
| NAID | 120007019117 |
| Web of Science KeyUT | 000627856600002 |
| 関連URL | isVersionOf https://doi.org/10.1186/s13075-021-02466-2 |
| フルテキストURL | fulltext20210530_4.pdf |
|---|---|
| 著者 | Kitagawa, Masaki| Ito, Nanako| Matsumoto, Yuya| Saito, Masaya| Tamura, Takashi| Kusakabe, Hitoshi| Inagaki, Kenji| Imada, Katsumi| |
| キーワード | L-Lysine α-oxidase Crystal structure Precursor Substrate recognition |
| 発行日 | 2021-12-31 |
| 出版物タイトル | Journal of Structural Biology: X |
| 巻 | 5巻 |
| 出版者 | Elsevier |
| 開始ページ | 100044 |
| ISSN | 25901524 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 33554108 |
| DOI | 10.1016/j.yjsbx.2021.100044 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.yjsbx.2021.100044 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumoto, Masakazu| Yagasaki, Takuma| Tanaka, Hideki| |
| 備考 | This fulltext is available in March 2022.| |
| 発行日 | 2021-03-01 |
| 出版物タイトル | The Journal of Chemical Physics |
| 巻 | 154巻 |
| 号 | 9号 |
| 出版者 | AIP Publishing |
| 開始ページ | 094502 |
| ISSN | 0021-9606 |
| NCID | AA00694991 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | publisher |
| PubMed ID | 33685157 |
| DOI | 10.1063/5.0044300 |
| Web of Science KeyUT | 000630524700002 |
| 関連URL | isVersionOf https://doi.org/10.1063/5.0044300 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsumoto, Namiko| Ohta, Yasuyuki| Deguchi, Kentaro| Kishida, Masayuki| Sato, Kota| Shang, Jingwei| Takemoto, Mami| Hishikawa, Nozomi| Yamashita, Toru| Watanabe, Aki| Yokote, Koutaro| Takemoto, Minoru| Oshima, Junko| Abe, Koji| |
| キーワード | werner syndrome compound heterozygous Japanese |
| 発行日 | 2019-04-01 |
| 出版物タイトル | Internal Medicine |
| 巻 | 58巻 |
| 号 | 7号 |
| 出版者 | Japanese Society of Internal Medicine |
| 開始ページ | 1033 |
| 終了ページ | 1036 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 by The Japanese Society of Internal Medicine |
| 論文のバージョン | publisher |
| PubMed ID | 30568144 |
| DOI | 10.2169/internalmedicine.1816-18 |
| Web of Science KeyUT | 000463190700024 |
| 関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.1816-18 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Hayashi, Keigo| Watanabe, Haruki| Yamamura, Yuriko| Asano, Yosuke| Katayama, Yukitoshi| Hiramatsu-Asano, Sumie| Ohashi, Keiji| Morishita, Michiko| Narazaki, Mariko| Matsumoto, Yoshinori| Sada, Ken-Ei| Wada, Jun| |
| キーワード | bronchial stenosis granulomatosis with polyangiitis hypertrophic pachymeningitis rituximab |
| 発行日 | 2021-01-22 |
| 出版物タイトル | Medicine |
| 巻 | 100巻 |
| 号 | 3号 |
| 出版者 | Lippincott, Williams & Wilkins |
| 開始ページ | e24028 |
| ISSN | 0025-7974 |
| NCID | AA00728867 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 33546000 |
| DOI | 10.1097/MD.0000000000024028 |
| Web of Science KeyUT | 000612835100080 |
| 関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000024028 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Uneda, Atsuhito| Kurozumi, Kazuhiko| Fujimura, Atsushi| Fujii, Kentaro| Ishida, Joji| Shimazu, Yosuke| Otani, Yoshihiro| Tomita, Yusuke| Hattori, Yasuhiko| Matsumoto, Yuji| Tsuboi, Nobushige| Makino, Keigo| Hirano, Shuichiro| Kamiya, Atsunori| Date, Isao| |
| キーワード | Differentiated glioblastoma cell Glioblastoma stem cell CCN1 YAP/TAZ TEAD Mesenchymal subtype Macrophage Microenvironment Glioma Glioblastoma |
| 発行日 | 2021-02-22 |
| 出版物タイトル | Acta Neuropathologica Communications |
| 巻 | 9巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 29 |
| ISSN | 2051-5960 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021. |
| 論文のバージョン | publisher |
| PubMed ID | 33618763 |
| DOI | 10.1186/s40478-021-01124-7 |
| Web of Science KeyUT | 000620598700001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s40478-021-01124-7 |
| JaLCDOI | 10.18926/AMO/61438 |
|---|---|
| フルテキストURL | 75_1_79.pdf |
| 著者 | Yoshio, Kotaro| Nagasaka, Hisako| Hisazumi, Kento| Okawa, Hiro| Tajiri, Nobuhisa| Shiode, Tsuyoki| Akaki, Shiro| Kanazawa, Susumu| Mitoma, Tomohiro| Yano, Yuri| Kobayashi, Emiko| Horiguchi, Ikuyo| Takata, Masayo| Hongo, Atsushi| Yonezawa, Masaru| Nakanishi, Yoshie| |
| 抄録 | The purposes of this retrospective study were to analyze local control of squamous cell carcinoma of the cervix treated with computed tomography (CT)-based image-guided brachytherapy (IGBT), as well as the factors affecting local control. A total of 39 patients were analyzed. The prescribed dose to the pelvis was 45-50 Gy with or without central shielding (CS). IGBT was delivered in 1-5 fractions. The total dose for high-risk clinical target volume (HR-CTV) was calculated as the biologically equivalent dose in 2-Gy fractions. The median follow-up period was 29.3 months. The 2-year overall survival and local control rates were 97% and 91%, respectively. In univariate analysis, the dose covering 90% of the HR-CTV (D90) and tumor size were found to be significant factors for local control. The cutoff values of tumor size and D90 for local control were 4.3 cm (area under the curve [AUC] 0.75) and 67.7 Gy (AUC 0.84) in the CS group and 5.3 cm (AUC 0.75) and 73.7 Gy (AUC 0.78) in the group without CS, respectively. However, though the local control of CT-based IGBT was favorable, the results suggested that the dose required for tumor control may differ depending on the presence of CS. |
| キーワード | cervical cancer squamous cell cancer brachytherapy central shielding |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-02 |
| 巻 | 75巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 79 |
| 終了ページ | 85 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33649617 |