検索結果 - 岡山大学学術成果リポジトリ

Relationships among Bone Metabolic Markers, Body Fat Composition and Carotid Intima–Media Thickness in Premenopausal Obese Women

JaLCDOI	10.18926/AMO/62233
フルテキストURL	75_3_373.pdf
著者	Yaylali, Guzin F.\| Dedeoglu, Ozen \| Topsakal, Senay\| Herek, Duygu\| Senol, Hande\|
抄録	Osteocalcin (OC) is inversely related to body fat distribution and fasting glucose levels. We sought to observe the effect of OC on fat distribution and subclinical atherosclerosis as measured by carotid intima-media thickness (CIMT) in premenopausal obese women. In this prospective observational study, totally, 73 premenopausal obese women (aged 17-55 years) and 53 healthy women (aged 20-50 years) with normal weight were included as controls. Anthropometric measurements, total fat and fat ratio, insulin, fasting blood glucose, and OC levels were estimated. Ultrasonography was used to assess fat distribution, and fat thickness was measured in 4 regions. Subcutaneous fat (SCF), visceral fat (VF), and preperitoneal fat (PPF) thicknesses were considerably higher in obese subjects (p<0.01) than healthy controls, while OC levels were significantly lower. No correlation was observed between OC levels and SCF, VF, or PPF. In a multiple regression analysis, OC was significantly positively associated with SCF (p=0.04, Beta=0.284). No associations were observed between OC levels and VF, PPF, or CIMT. A significant association was observed between parathyroid hormone (PTH) and VF (p=0.021, Beta=0.284), and vitamin D levels were inversely associated with VF (p=0.002, r=−0.366). OC levels were lower in premenopausal obese women than normal-weight healthy controls, but OC exhibited no correlation with VF or PPF, and only a weak positive association with SCF. Additionally, VF was positively correlated with PTH and inversely correlated with vitamin D. These results suggest that OC may be an early indicator of lipid accumulation in te subcutaneous area and development of atherosclerosis.
キーワード	body fat composition carotid intima-media thickness obesity osteocalcin premenopausal women
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	373
終了ページ	379
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176942
Web of Science KeyUT	000667147700013
NAID	120007089830

Investigation into the Effect of Breast Volume on Irradiation Dose Distribution in Asian Women with Breast Cancer

JaLCDOI	10.18926/AMO/62225
フルテキストURL	75_3_307.pdf
著者	Ishizaka, Hinata\| Kuroda, Masahiro\| Tekiki, Nouha\| Khasawneh, Abdullah\| Barham, Majd\| Hamada, Kentaro\| Konishi, Kohei\| Sugimoto, Kohei\| Katsui, Kuniaki\| Sugiyama, Soichi\| Watanabe, Kenta\| Yoshio, Kotaro \| Katayama, Norihisa\| Ogata, Takeshi\| Ihara, Hiroki\| Oita, Masataka\| Kanazawa, Susumu\| Asaumi, Junichi\|
抄録	Reports on irradiation dose distribution in breast cancer radiotherapy with sufficient sample size are limited in Asian patients. Elucidating dose distribution in Asian patients is particularly important as their breast volume differs compared to patients in Europe and North America. Here, we examined dose distribution in the irradiation field relative to breast volume for three irradiation methods historically used in our facility. We investigated the influence of breast volume on each irradiation method for Asian women. A total of 573 women with early-stage breast cancer were treated with breast-conserving surgery and adjuvant radiotherapy. Three methods were compared: wedge (W), field-in-field (FIF), and wedge-field-in-field (W-FIF). In patients with small breast volume, FIF decreased low- and high-dose areas within the planning target volume, and increased optimal dose area more than W. In patients with medium and large breast volumes, FIF decreased high-dose area more than W. The absolute values of correlation coefficients of breast volume to low-, optimal-, and high-dose areas and mean dose were significantly lower in FIF than in W. The correlation coefficients of V107% were 0.00 and 0.28 for FIF and W, respectively. FIF is an excellent irradiation method that is less affected by breast volume than W in Asian breast cancer patients.
キーワード	breast cancer radiotherapy dose distribution irradiation method breast volume
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	307
終了ページ	314
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176934
Web of Science KeyUT	000667147700006
NAID	120007089838

Interrelationships Between Serum Levels of Procalcitonin and Inflammatory Markers in Patients Who Visited a General Medicine Department

JaLCDOI	10.18926/AMO/62221
フルテキストURL	75_3_299.pdf
著者	Araki, Jo\| Oka, Kosuke\| Yamamoto, Koichiro\| Hanayama, Yoshihisa \| Tokumasu, Kazuki\| Hagiya, Hideharu\| Ogawa, Hiroko\| Itoshima, Koichi\| Otsuka, Fumio\|
抄録	Various laboratory markers of inflammation are utilized in general practice, but their clinical diagnostic significance is often ambiguous. In the present study, we determined the clinical significance of the examination of serum levels of procalcitonin (PCT) by comparing the PCT levels with the levels of other inflammatory markers, based on a retrospective review of 332 PCT-positive patients, including cases of bacterial infection (20.5%), non-specific inflammation (20.8%), neoplasm (9.9%), connective tissue diseases (8.4%), and non-bacterial infection (7.2%), were analyzed. The serum PCT level was highest in the bacterial infection group (1.94 ng/ml) followed by the non-specific inflammatory group (0.58 ng/ml) and neoplastic diseases group (0.34 ng/ml). The serum PCT level was positively correlated with serum levels of C-reactive protein (rho=0.62), soluble interleukin-2 receptor (sIL-2R; rho=0.69), and ferritin, the plasma level of D-dimer, and white blood cell count, and negatively correlated with the serum albumin level (rho=−0.52), hemoglobin concentration, and platelet count. The serum PCT level showed a stronger positive correlation with the serum sIL-2R level than the other biomarkers. The results suggest that an increased PCT level may indicate not only an infectious state but also a non-bacterial inflammatory condition in the diagnostic process in general practice.
キーワード	bacterial infection inflammation malignant lymphoma procalcitonin soluble interleukin-2 receptor
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	299
終了ページ	306
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176933
Web of Science KeyUT	000667147700005
NAID	120007089836

Efficacy and Safety of Early Intravenous Landiolol on Myocardial Salvage in Patients with ST-segment Elevation Myocardial Infarction before Primary Percutaneous Coronary Intervention: A Randomized Study

JaLCDOI	10.18926/AMO/62220
フルテキストURL	75_3_289.pdf
著者	Miyamoto, Masakazu\| Osawa, Kazuhiro\| Miyoshi, Toru\| Mori, Atsushi\| Yoshikawa, Masaki\| Oka, Takefumi\| Ichikawa, Keishi\| Nakamura, Kazufumi\| Ito, Hiroshi\|
抄録	Early treatment with an oral β-blocker is recommended in patients with a ST-segment–elevation myocardial infarction (STEMI). In this multicenter study, we evaluated the effects of a continuous administration of landiolol, an ultrashort-acting β-blocker, before primary percutaneous coronary intervention (PCI) on myocardial salvage and its safety in STEMI patients. A total of 47 Japanese patients with anterior or lateral STEMI undergoing a primary PCI within 12 h of symptom onset were randomized to receive intravenous landiolol (started at 3 μg/min/kg dose and continued to a total of 50 mg; n=23) or not (control; n=24). Patients with Killip class III or more were excluded. The primary outcome was the myocardial salvage index on cardiac magnetic resonance imaging (MRI) performed 5-7 days after the PCI. Cardiac MRI was performed in 35 patients (74%). The myocardial salvage index in the landiolol group was significantly greater than that in the control group (44.4±14.6% vs. 31.7±18.9%, respectively; p=0.04). There were no significant differences in adverse events at 24 h between the landiolol and control groups. A continuous administration of landiolol before a primary PCI may increase the degree of myocardial salvage without additional hemodynamic adverse effects within the first 24 h after STEMI.
キーワード	myocardial infarction landiolol magnetic resonance imaging STEMI PCI
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	289
終了ページ	297
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176932
Web of Science KeyUT	000667147700004
NAID	120007089835

A Case of Dual-pathology Hepatocellular Carcinoma (HCC) and Cholangiolocellular Carcinoma (CoCC) after Eradication of Hepatitis C Virus (HCV) Infection

JaLCDOI	10.18926/AMO/61903
フルテキストURL	75_2_213.pdf
著者	Miyashita, Manabi\| Saragai, Yousuke\| Fujimoto, Tsuyoshi\| Tanaka, Shouichi\| Aoki, Hideki\| Sato, Yumiko \|
抄録	A 75-year-old Japanese man visited our hospital for further examination of liver tumors. He had a history of successful hepatitis C virus (HCV) eradication and therapy for hepatocellular carcinoma (HCC) at another hospital. Magnetic resonance imaging (MRI) revealed two tumors in the liver. He underwent anterior inferior (S5) and posterior inferior (S6) subsegmentectomy of the liver. Microscopic examination found that one tumor was HCC while the other was cholangiolocellular carcinoma (CoCC). We experienced a rare case of liver cancer with two synchronous pathologies, HCC and CoCC.
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	213
終了ページ	218
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953428
NAID	120007029884

Multiacquisition Variable-Resonance Image Combination Selective Can Improve Image Quality and Reproducibility for Metallic Implants in the Lumbar Spine

JaLCDOI	10.18926/AMO/61897
フルテキストURL	75_2_187.pdf
著者	Fujiwara, Yuta\| Sasaki, Tomoaki\| Muto, Yuki\| Hirano, Masaki\| Kamizaki, Ryo\| Murakami, Kaito\| Miura, Naoya\| Fujibuchi, Yutaka\| Ohmukai, Nayu\| Ueda, Nao \| Sugimoto, Kouhei \| Ota, Kazuhiro\| Kamihoriuchi, Yoshiki\| Sasaki, Tomoko\| Kaneshige, Souichirou\|
抄録	The aim of this study is to evaluate how metallic artifacts in the lumbar spine can affect images obtained from magnetic resonance (MR) sequences. We performed a phantom experiment by scanning an agar containing an orthopedic metallic implant using 64-channel multidetector row computed tomography (CT) and a 3-tesla MR unit. We compared the reproducibility in each measurement, enlargement or reduction ratio of the CT and MR measurements, and signal deviation in each voxel from the control. The reproducibility on CT and multiacquisition variable-resonance image combination selective (MAVRIC SL) was good, but that on the other MR sequences showed either fixed bias or proportional bias. The reduction ratios of the distance between the nails were significantly smaller in MAVRIC SL than in the other MR sequences after CT measurements (p<0.001, respectively). MAVRIC SL was able to reduce the metallic artifact, permitting observation of the tissue surrounding the metal with good reproducibility.
キーワード	metallic artifact reduction implant MAVRIC SL
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	187
終了ページ	197
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953425
NAID	120007029889

The Effects of Low-Dose-Rate γ-irradiation on Forced Swim Test-Induced Immobility and Oxidative Stress in Mice

JaLCDOI	10.18926/AMO/61896
フルテキストURL	75_2_169.pdf
著者	Nakada, Tetsuya\| Kataoka, Takahiro\| Nomura, Takaharu\| Shuto, Hina\| Yano, Junki\| Naoe, Shota\| Hanamoto, Katsumi\| Yamaoka, Kiyonori\|
抄録	The forced swim test (FST) induces immobility in mice. Low-dose (high-dose-rate) X-irradiation inhibits FSTinduced immobility in mice due to its antioxidative function. We evaluated the effects of low-dose γ-irradiation at a low-dose-rate on the FST-induced depletion of antioxidants in mouse organs. Mice received whole-body low-dose-rate (0.6 or 3.0 mGy/h) of low-dose γ-irradiation for 1 week, followed by daily FSTs (5 days). The immobility rate on day 2 compared to day 1 was significantly lower in the 3.0 mGy/h irradiated mice than in sham irradiated mice. The FST significantly decreased the catalase (CAT) activity and total glutathione (t-GSH) content in the brain and kidney, respectively. The superoxide dismutase (SOD) activity and t-GSH content in the liver of the 3.0 mGy/h irradiated mice were significantly lower than those of the non-FST-treated mice. The CAT activity in the lungs of mice exposed to 3.0 mGy/h γ-irradiation was higher than that of non-FST treated mice and mice treated with FST. However, no significant differences were observed in the levels of these antioxidant markers between the sham and irradiated groups except for the CAT activity in lungs. These findings suggest that the effects of low-dose-rate and low-dose γ-irradiation on FST are highly organ-dependent.
キーワード	low-dose-rate γ-irradiation forced swim test antioxidant oxidative stress
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	169
終了ページ	175
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953424
NAID	120007029890

Efficacy and Safety of Ramucirumab/nab-paclitaxel for Previously Treated Advanced Gastric Cancer in Community Hospitals

JaLCDOI	10.18926/AMO/61879
フルテキストURL	75_2_133.pdf
著者	Hashida, Shinsuke\| Tanaka, Norimitsu\| Takahashi, Yuta\| Onoda, Yuji\| Colvin, Hugh Shunsuke\| Ohashi, Ryuichiro\| Okamoto, Kunio \|
抄録	As the nanoparticle albumin-bound paclitaxel (nab-PTX) is free of ethanol and premedication, the duration of administration is shorter and patients can drive themselves to and from the hospital. In the 2018 Japanese gastric cancer treatment guidelines, ramucirumab (RAM) plus weekly nab-PTX is conditionally recommended for previously treated patients with advanced gastric cancer. Here, we retrospectively analysed the efficacy and safety of RAM+nab-PTX for such patients in community hospitals. From January 2018 to December 2019, 43 patients with metastatic and recurrent gastric cancer received RAM+nab-PTX treatment. Six patients (13.9%) were older than 80 years and 9 patients (20.9%) showed ECOG-PS 2. Progression-free survival (PFS), overall survival (OS), overall response rate (ORR), disease control rate (DCR), and adverse events (AEs) were reviewed retrospectively. Median PFS was 114 days (95% confidence interval [CI]: 84-190) and median OS was 297 days (95% CI: 180-398). ORR and DCR were 32.4% and 72.2%, respectively. The incidence rates of ≥grade 3 neutropenia and febrile neutropenia were 53.5% and 2.3%, respectively. No treatment-related deaths occurred. RAM plus nab-PTX combination therapy demonstrated manageable toxicity even patients who were elderly or had an ECOG-PS 2. This treatment is useful in community hospital settings.
キーワード	gastric cancer ramucirumab nab-paclitaxel
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	133
終了ページ	138
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953419
NAID	120007029904

Bone Histomorphometry of Femoral Head Cancellous Bone in Patients Who Underwent Total Hip Arthroplasties due to Destructive Hip in Rheumatoid Arthritis

JaLCDOI	10.18926/AMO/61878
フルテキストURL	75_2_125.pdf
著者	Kijima, Yasufumi\| Kondo, Naoki\| Okumura, Go\| Endo, Naoto\|
抄録	Rheumatoid arthritis (RA) affects the hip joints. The microarchitecture of the cancellous bone in RA-affected hip joints has been unclear. Here we investigated the bone metabolism changes in the subcapital cancellous bone of destructive hips of RA patients (n=26 patients; 28 hip joints) which were classified by Larsen grade on X-ray into the groups: destructive hip (Des) (Larsen grade IV, n=18) and neck fracture (Fx) (Larsen grade 0 or 1, n=10). The femoral heads of the Des-group showed significantly higher trabecular thickness versus those of the Fx-group (179±30.8 vs. 151±23.5 μm, p=0.02). The Des-group had significantly higher osteoid volume/tissue volume (OV/TV) and osteoid volume/bone volume (OV/BV) ratios than the Fx-group (OV/TV: 0.72±0.70% vs. 0.27±0.32%, p=0.028; OV/BV: 2.96±2.85% vs. 1.24±1.31%, p=0.039). The osteoblast and osteoclast surface areas of the Des-group were remarkably higher than those of the Fx-group (9.80±10.9 vs. 0.15±0.15%, p=0.0005; 0.34±0.48 vs. 0.06±0.06%, p=0.0285, respectively). The T-scores of hip (femoral neck) bone mineral density (BMD) of the Fx-group were significantly lower versus those of the Des-group (−3.1±0.76 vs. −1.6±1.17, p<0.01). Increased osteoid and resorption parameters and higher femoral neck BMD demonstrate a high bone-turnover state in response to destructive changes in the hips of RA patients.
キーワード	bone histomorphometry rheumatoid arthritis destructive hip femoral neck fracture bone turnover
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	125
終了ページ	131
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953418
NAID	120007029905

Awareness of Complications of Dental Treatment in Patients Treated with Drugs Affecting the Immune System : A Nationwide Questionnaire Survey of Dental Practitioners in Japan

JaLCDOI	10.18926/AMO/61877
フルテキストURL	75_2_115.pdf
著者	Hitomi, Nishizaki\| Yoshinari, Morimoto\| Yamada, Shin-ichi\| Kurita, Hiroshi\| Tanaka, Akira\| Yamaguchi, Akira\| Miyata, Masaru\| Yoshikawa, Hiromasa \| Yanamoto, Souichi\| Imai, Yutaka\|
抄録	The aim of this study was to investigate the awareness and experience, among dental practitioners, of adverse events resulting from dental treatment of patients undergoing therapy with drugs that affect the immune system [angiogenesis inhibitors, biological agents, immunosuppressants, and disease-modifying anti-rheumatic drugs (DMARDs)]. For this purpose, a nationwide questionnaire survey was conducted. Questionnaires were sent to 2,050 dentists, of which 206 (10.1%) were completed and returned. The results showed that most dentists were aware of complications associated with dental treatment of patients treated with drugs that affect the immune system, and about half had actually experienced such complications. Delayed wound healing, osteonecrosis of the jaw (ONJ), and postoperative infections were reported. Whereas approximately 50% of dentists did not discontinue the drugs during dental treatment, about 18% did. During temporary drug discontinuation, some patients experienced aggravation of the primary disease, such as worsening of rheumatism, growth of tumors, and rejection reactions of transplanted organs. As for medical cooperation, only less than half of the dentists were asked for oral hygiene management by a physician prior to starting the drug treatment. Prospective studies are needed because evidence for dental treatments in patients treated with these drugs remains limited.
キーワード	angiogenesis inhibitor biological agent disease-modifying antirheumatic drug (DMARD) immunosuppressant medication-related osteonecrosis of the jaw (MRONJ)
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	115
終了ページ	123
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953417
NAID	120007029906

Imaging evaluation of hereditary renal tumors: a pictorial review

フルテキストURL	fulltext20210413_1.pdf
著者	Tanaka, Takashi\| Kawashima, Akira\| Marukawa, Yohei\| Kitayama, Takahiro\| Masaoka, Yoshihisa\| Kojima, Katsuhide\| Iguchi, Toshihiro\| Hiraki, Takao\| Kanazawa, Susumu\|
キーワード	Hereditary renal tumor syndrome Von Hippel–Lindau disease Birt–Hogg–Dubé syndrome Tuberous sclerosis complex Hereditary leiomyomatosis and renal cell carcinoma syndrome
備考	This is an Accepted Manuscript of an article published by Springer. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s11604-021-01109-5\|
発行日	2021-3-23
出版物タイトル	Japanese Journal of Radiology
巻	39巻
出版者	Springer Science and Business Media LLC
開始ページ	619
終了ページ	632
ISSN	1867-1071
NCID	AA12375935
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	©Japan Radiological Society 2021
論文のバージョン	author
PubMed ID	33759057
DOI	10.1007/s11604-021-01109-5
NAID	130008000092
Web of Science KeyUT	000631734600001
関連URL	isVersionOf https://doi.org/10.1007/s11604-021-01109-5

Learning curves of minimally invasive donor nephrectomy in a high-volume center: A cohort study of 1895 consecutive living donors

フルテキストURL	fulltext20210519_1.pdf
著者	Takagi, Kosei\| Kimenai, Hendrikus J.A.N.\| Terkivatan, Turkan\| Tran, Khe T.C.\| Ijzermans, Jan N.M.\| Minnee, Robert C.\|
キーワード	Kidney transplantation Learning curve Hand-assisted laparoscopy Laparoscopy Living donors Nephrectomy Teaching Robotic surgical procedures
発行日	2021-02-28
出版物タイトル	International Journal of Surgery
巻	86巻
出版者	Elsevier
開始ページ	7
終了ページ	12
ISSN	17439191
NCID	AA12063080
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Author(s).
論文のバージョン	publisher
PubMed ID	33429077
DOI	10.1016/j.ijsu.2020.12.011
関連URL	isVersionOf https://doi.org/10.1016/j.ijsu.2020.12.011

Intravesical Therapy in Patients with Intermediate-risk Non–muscle-invasive Bladder Cancer: A Systematic Review and Network Meta-analysis of Disease Recurrence

フルテキストURL	fulltext20210525_1.pdf
著者	Laukhtina, Ekaterina\| Abufaraj, Mohammad\| Al-Ani, Abdallah\| Ali, Mustafa Rami\| Mori, Keiichiro\| Moschini, Marco\| Quhal, Fahad\| Sari Motlagh, Reza\| Pradere, Benjamin\| Schuettfort, Victor M.\| Mostafaei, Hadi\| Katayama, Satoshi\| Grossmann, Nico C.\| Fajkovic, Harun\| Soria, Francesco\| Enikeev, Dmitry\| Shariat, Shahrokh F.\|
キーワード	Non–muscle-invasive bladder cancer Bladder cancer Intermediate risk Intravesical therapy Network meta-analysis
発行日	2021-03-21
出版物タイトル	European Urology Focus
出版者	Elsevier
ISSN	24054569
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
PubMed ID	33762203
DOI	10.1016/j.euf.2021.03.016
NAID	120007039929
関連URL	isVersionOf https://doi.org/10.1016/j.euf.2021.03.016

Dysostosis in mucopolysaccharidosis type 2: A case of longitudinal follow up and literature review

フルテキストURL	fulltext20210525_3.pdf
著者	Sasaki, Tomoaki\| Ogata, Miki\| Kajihama, Aya\| Nakau, Kouichi\| Okizaki, Atsutaka\|
キーワード	Mucopolysaccharidosis type 2 Dysostosis Cranial hyperostosis
発行日	2021-03-31
出版物タイトル	Radiology Case Reports
巻	16巻
号	3号
出版者	Elsevier
開始ページ	656
終了ページ	660
ISSN	19300433
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
PubMed ID	33488893
DOI	10.1016/j.radcr.2021.01.003
関連URL	isVersionOf https://doi.org/10.1016/j.radcr.2021.01.003

Direct evidence of electronic ferroelectricity in YbFe2O4 using neutron diffraction and nonlinear spectroscopy

フルテキストURL	fulltext.pdf
著者	Fujiwara, K.\| Fukada, Y.\| Okuda, Y.\| Seimiya, R.\| Ikeda, N.\| Yokoyama, K.\| Yu, H.\| Koshihara, S.\| Okimoto, Y.\|
発行日	2021-2-19
出版物タイトル	Scientific Reports
巻	11巻
号	1号
出版者	Springer
開始ページ	4277
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The author(s) 2021
論文のバージョン	publisher
DOI	10.1038/s41598-021-83655-6
関連URL	isVersionOf https://doi.org/10.1038/s41598-021-83655-6

Long-term Follow-up of Living-Donor Kidney Transplantation after Cadaveric Lung Transplantation

JaLCDOI	10.18926/AMO/61439
フルテキストURL	75_1_87.pdf
著者	Shiotani, Toshio\| Sugimoto, Seiichiro\| Araki, Kota\| Tomioka, Yasuaki\| Miyoshi, Kentaroh\| Otani, Shinji\| Yamane, Masaomi\| Toyooka, Shinichi\|
抄録	Although chronic kidney disease (CKD) commonly develops after lung transplantation (LT), living-donor kid-ney transplantation (LDKT) for CKD after LT is known to provide favorable outcomes. We describe the long-term follow-up findings of a patient who underwent LDKT after bilateral cadaveric LT. A 37-year-old male underwent LDKT for CKD 18 years after receiving bilateral cadaveric LT. He developed chronic lung allograft dysfunction (CLAD) 20 years after the LT; however, at 26 years after the initial LT, he is still alive with no pro-gression of CLAD or CKD. KT could be a viable option for CKD even after LT in Japan.
キーワード	lung transplantation kidney transplantation chronic kidney disease non-tuberculous mycobacterial infection chronic lung allograft dysfunction
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	87
終了ページ	89
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649618

The Thickness of the Medial Wall of the Acetabulum Prevents Acetabular Fracture during the Insertion of a Cementless Cup in Total Hip Arthroplasty: A Biomechanical Study

JaLCDOI	10.18926/AMO/61437
フルテキストURL	75_1_71.pdf
著者	Sanki, Tomoaki\| Tetsunaga, Tomonori\| Furumatsu, Takayuki\| Yamada, Kazuki\| Kawamura, Yoshi\| Ozaki, Toshifumi\|
抄録	Intra-operative acetabular fracture is a total hip arthroplasty complication that can occur during cementless cup insertion, especially in osteoporotic patients. We conducted this biomechanical study to investigate the impact resistance of the acetabulum with simulated bones of different density by drop-weight impact testing. Low- and high-density polyurethane foam blocks were used as osteoporotic and healthy bone models, respectively. Polyurethane blocks were used as the acetabular cancellous bone. Composite sheets were used as the acetabu-lum’s medial cortex. The testing revealed that the osteoporotic bone model’s impact resistance was significantly lower than that the healthy bone model’. In the healthy bone model, even thin acetabular cancellous bone with ≥ 1 mm acetabulum medial cortex was less likely to fracture. In the osteoporotic bone model, fracture was pos-sible without ≥ 1 mm medial cortex of the acetabulum and thick acetabular cancellous bone. Although impac-tion resistance differs due to bone quality, the impaction resistance in this osteoporotic bone model was equiv-alent to that healthy bone model’s when a thick medial wall was present. To avoid intra-operative acetabulum fracture, surgeons should consider both the bone quality and the thicknesses of the medial cortex and acetabu-lar cancellous bone.
キーワード	intra-operative acetabular fracture drop weight impact testing total hip arthroplasty impact resistance
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	71
終了ページ	77
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649616

Possible Protective Effect of Remote Ischemic Preconditioning on Acute Kidney Injury Following Elective Percutaneous Coronary Intervention: Secondary Analysis of a Multicenter, Randomized Study

JaLCDOI	10.18926/AMO/61433
フルテキストURL	75_1_45.pdf
著者	Otsuka, Hiroaki\| Miyoshi, Toru\| Ejiri, Kentaro\| Kohno, Kunihisa\| Nakahama, Makoto\| Doi, Masayuki\| Munemasa, Mitsuru\| Murakami, Masaaki\| Nakamura, Kazufumi\| Ito, Hiroshi\|
抄録	Remote ischemic preconditioning (RIPC) is a promising strategy for protecting against ischemic reperfusion injury. This study is a secondary analysis of a randomized study that aimed to evaluate the effect of RIPC on the early increase in serum creatinine (SCr) following percutaneous coronary intervention (PCI), which is associ-ated with contrast-induced acute kidney injury. Patients with stable angina undergoing elective PCI were assigned to control, RIPC, and continuous infusion of nicorandil (nicorandil) groups. The endpoint of this study was the incidence of the early increase in SCr, a predictor of contrast-induced acute kidney injury, which was defined as either a > 20% or absolute increase by 0.3 mg/dl of SCr levels after 24 h of PCI. This study included 220 patients for whom a dataset of SCr values was available. The incidence of the early increase in SCr was significantly lower in the RIPC than in the control (1.3% vs 10.8%, p = 0.03) group, but was not significantly different between the nicorandil and control groups. In multivariate analysis, RIPC remained a significant fac-tor associated with a reduction in the incidence of early increase in SCr. RIPC reduces the incidence of early increase in SCr in patients with stable angina following elective PCI.
キーワード	remote ischemic preconditioning stable angina serum creatinine acute kidney injury
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	45
終了ページ	53
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649613

Influence of and Risk Factors for Axillary Web Syndrome Following Surgery for Breast Cancer

JaLCDOI	10.18926/AMO/61432
フルテキストURL	75_1_39.pdf
著者	Akezaki, Yoshiteru\| Nakata, Eiji\| Kikuuchi, Masato\| Tominaga, Ritsuko\| Kurokawa, Hideaki\| Hamada, Makiko\| Aogi, Kenjiro\| Ohsumi, Shozo\| Sugihara, Shinsuke\|
抄録	In this study, we examined whether axillary web syndrome (AWS) in patients with breast cancer following axil-lary lymph node dissection affects range of motion (ROM), upper extremity function, and quality of life (QOL). The risk factors for AWS were also evaluated in a total of 238 consecutive breast cancer patients follow-ing axillary lymph node dissection. At 1, 2, and 3 months after surgery, there were no significant differences between the AWS group and the non-AWS group in upper-limb function or QOL. At 2 months after surgery, shoulder flexion and abduction ROM were significantly higher in the AWS group than in the non-AWS group (p < 0.05). Self-training time at home was not significantly different between the groups at 1, 2, or 3 months. Only age was a significant predictor of AWS at 1 month after surgery (p < 0.05). The AWS group in the present study did not have worse results for shoulder joint ROM, upper-limb function, and QOL than the non-AWS group. Younger age should be useful for predicting the development of AWS in the early postoperative period.
キーワード	breast cancer axillary web syndrome age upper limb function quality of life
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	39
終了ページ	44
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649612

Treatment Outcomes of Pulmonary Metastases from Head and Neck Squamous Cell Carcinoma

JaLCDOI	10.18926/AMO/61431
フルテキストURL	75_1_31.pdf
著者	Miyamaru, Satoru\| Murakami, Daizo\| Nishimoto, Kohei\| Saito, Haruki\| Miyamoto, Yusuke\| Hirota, Kaoruko\| Ise, Momoko\| Orita, Yorihisa\|
抄録	Although the lung is the most common site of distant metastases from head and neck squamous cell carcinoma (HNSCC), the number of reports about the effects of pulmonary metastasectomy for the treatment of lung metastasis from HNSCC is limited. Metachronous pulmonary metastases were detected in 45 HNSCC patients at Kumamoto University Hospital from 1998 to 2018. Twenty-two patients underwent an operative resection (Ope group) and 23 underwent chemotherapy (Chemo group). The 3-year overall survival (OS) rate and median OS were evaluated. The effects of adjuvant chemotherapy after pulmonary metastasectomy and of new drugs (cetuximab and nivolumab), in the chemo group were also assessed. The 3-year OS rates and median OS were: Ope, 66.1% and 31.5 months; Chemo, 39.7% and 18 months, respectively. In the Ope group, addi-tional recurrences were significantly fewer in the patients who underwent adjuvant chemotherapy post-surgery versus the patients who underwent surgery alone (p = 0.013). In the Chemo group, the 3-year OS rate of the patients who received new drugs was significantly better than that of the patients who did not (p = 0.021). Adjuvant chemotherapy after pulmonary metastasectomy may be a preferable treatment option for preventing recurrences. Cetuximab and nivolumab have a potential to improve OS.
キーワード	pulmonary metastasis head and neck squamous cell carcinoma pulmonary metastasectomy adjuvant chemotherapy
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	31
終了ページ	37
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649611