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タイトル(別表記) General Practitioner
フルテキストURL 130_167.pdf
著者 小比賀 美香子| 片岡 仁美| 小川 弘子| 大塚 文男|
キーワード 新専門医制度 総合診療専門医
出版物タイトル 岡山医学会雑誌
発行日 2018-12-03
130巻
3号
開始ページ 167
終了ページ 172
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.130.167
言語 日本語
著作権者 Copyright (c) 2018 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.130.167
NAID 130007542846
タイトル(別表記) Introduction of the dessin class in medical education:Sublimation from dessin to art
フルテキストURL 130_81.pdf
著者 大塚 益美| 松本 洋| 木股 敬裕|
出版物タイトル 岡山医学会雑誌
発行日 2018-08-01
130巻
2号
開始ページ 81
終了ページ 84
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.130.81
言語 日本語
著作権者 Copyright (c) 2018 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.130.81
NAID 130007481043
タイトル(別表記) An effective case of peroral endoscopic myotomy for esophageal abnormal peristalsis after Heller-Dor myotomy
フルテキストURL 130_67.pdf
著者 杉原 雄策| 原田 馨太| 加藤 諒| 山内 健司| 髙嶋 志保| 山崎 泰史| 井口 俊博| 高原 政宏| 川野 誠司| 平岡 佐規子| 眞部 紀明| 大塚 文男| 岡田 裕之|
抄録 Esophageal achalasia is a disorder of the lower esophageal sphincter muscle. Our patient, a Japanese male in his 80's, had been experiencing dysphagia for almost 60 years. He was treated with balloon dilations and Heller-Dor 5 years prior to his present admission. Esophagogastroduodenoscopy, esophageal radiography, and high-myotomy manometry indicated that the symptoms were likely due to abnormal peristalsis. With the patient’s informed consent, we performed a peroral endoscopic myotomy(POEM). The patient was discharged 4 days post-surgery. At the 6-month postoperative examination, no worsening of symptoms or relapse was observed. POEM is an excellent treatment method for esophageal achalasia from the perspective of therapeutic effect. We recommend that POEM be considered as the first-choice treatment for abnormal peristalsis after a Heller-Dor myotomy.
キーワード POEM(peroral endoscopic myotomy) 食道アカラシア(esophageal achalasia)
出版物タイトル 岡山医学会雑誌
発行日 2018-08-01
130巻
2号
開始ページ 67
終了ページ 71
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.130.67
言語 日本語
著作権者 Copyright (c) 2018 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.130.67
NAID 130007481050
タイトル(別表記) New System of Japanese Medical Specialty : Internal Medicine
フルテキストURL 130_25.pdf
著者 小比賀 美香子 | 大塚 文男 | 岡田 裕之|
出版物タイトル 岡山医学会雑誌
発行日 2018-04-02
130巻
1号
開始ページ 25
終了ページ 30
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.130.25
言語 日本語
著作権者 Copyright (c) 2018 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.130.25
NAID 130006730864
JaLCDOI 10.18926/OER/55744
タイトル(別表記) The Forest Environment and the Production of the Forest Products in Modern Okayama Prefecture Research focusing on Lumber and Wood Charcoal
フルテキストURL oer_049_3_039_064.pdf
著者 大塚 利昭|
抄録 In order to reveal the environmental history of the forest in Okayama Prefecture in the modern period, this paper analyzes the production situation of the forest products in the scenery of the change of the forest environment. As a result, the following items were found out.  After the Meiji period, Okayama Prefecture, which had been in middle or low-ranking as a position among the whole country as a place of production for lumber and wood charcoal, had produced forest products stably for a long term. The amounts of production of the forest products had gently increased after World War I in the background of the industrialization and urbanization until the early days of the Showa period. However, the situation had greatly changed when it entered World War II period, and the amount of production had increased remarkably up to the end of the war.  In Okayama of the Meiji period, erosion control works was prosperous so as to be located thirdly on a budget in the whole country. Therefore, there was the problem of“ Hageyama”, the bald mountain in Japanese, from early modern period. A remarkable increase in production of lumber and wood charcoal is confirmed for the wartime period around 1930, and this is thought to have pushed forward more forest dilapidation by statistics data. It was limited during the period of 10 ⊖ 20 years that excessive production was carried out. Since the forest conservation project was to increase the effect, now that 70 years after the war has passed, the forest is looking at a sufficiently recovered.  However, it is in condition that the forest was left untreated and is hard to say that the function of the public benefit that the forest has been shown continuously now. Based on the actual situation in the times while the production activities of forest products were carried out actively, drawing the future vision of forest will be necessary.
出版物タイトル 岡山大学経済学会雑誌
発行日 2018-03-19
49巻
3号
開始ページ 39
終了ページ 64
ISSN 2433-4146
言語 日本語
著作権者 Copyright © 2018 岡山大学経済学会
論文のバージョン publisher
NAID 120006414153
タイトル(別表記) Report of the 14th Annual Meeting of the Japanese Society of Hospital General Medicine
フルテキストURL 129_143.pdf
著者 大塚 文男|
出版物タイトル 岡山医学会雑誌
発行日 2017-08-01
129巻
2号
開始ページ 143
終了ページ 145
ISSN 0030-1558
関連URL https://doi.org/10.4044/joma.129.143
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.143
NAID 130006039380
フルテキストURL K0005446_abstract_review.pdf K0005446_summary.pdf K0005446_fulltext.pdf
著者 大塚 智昭|
発行日 2017-03-24
資料タイプ 学位論文
学位授与番号 甲第5446号
学位授与年月日 2017-03-24
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
JaLCDOI 10.18926/AMO/54977
フルテキストURL 71_2_97.pdf
著者 Iwamuro, Masaya| Kondo, Eisei| Tanaka, Takehiro| Hagiya, Hideharu| Kawano, Seiji| Kawahara, Yoshiro| Otsuka, Fumio| Okada, Hiroyuki|
抄録 We retrospectively analyzed the cases of 14 patients (9 women, 5 men, mean age: 51.6 years) with cytomegalovirus (CMV) involvement in the esophagus, stomach, and/or duodenum diagnosed at a single center, to determine their endoscopic features and clinical backgrounds. Thirteen patients (92.9%) had hematologic disease; the other had rheumatoid arthritis. Of the former, 12 patients underwent allogeneic hematopoietic stem cell transplantation, and 9 of these patients had graft-versus-host disease (GVHD) before undergoing esophagogastroduodenoscopy (EGD). All 14 patients had been taking one or more immunosuppressive agents including cyclosporine (n=10), corticosteroids (n=9), mycophenolic acid (n=6), tacrolimus (n=3), and methotrexate (n=1). Tests for CMV antigenemia were positive in 11 patients (78.6%). EGD examinations revealed esophageal (n=3), gastric (n=9), and duodenal involvement (n=6). Macroscopically, esophageal lesions by CMV infection presented as redness (n=1), erosions (n=1), and ulcers (n=1). Gastric lesions manifested as redness (n=7), erosions (n=3), exfoliated mucosa (n=2), and verrucous erosions (n=1). Mucosal appearances in the duodenum varied: redness (n=2), ulcers (n=2), multiple erosions (n=2), single erosion (n=1), edema (n=1). CMV was detected even in the intact duodenal mucosa (n=1). In conclusion, physicians must recall the relevance of CMV infection when any mucosal alterations exist in the upper gastrointestinal tract of immunosuppressed patients.
キーワード cytomegalovirus duodenum esophagogastroduodenoscopy esophagus stomach
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2017-04
71巻
2号
出版者 Okayama University Medical School
開始ページ 97
終了ページ 104
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28420890
タイトル(別表記) A refractory cutaneous-rectovesical fistula complicated with abdominal actinomycosis successfully treated with antibiotic therapy
フルテキストURL 129_35.pdf
著者 桂 佑貴| 松川 啓義| 加藤 卓也| 杉原 正大| 小島 康知| 塩崎 滋弘|
抄録 The patient was a 35-year-old Japanese man diagnosed with appendicitis with abscess formation. An appendectomy was performed, but a refractory surgical wound infection developed, and eventually a cutaneous-rectovesical fistula was detected. In a review of the first-time CT scan, a small high-density construction resembling a bone from a fish was detected in the ileum. The histopathological examination revealed granules of actinomyces. These findings suggested that abdominal actinomycosis due to intestinal mucosal breakage by the fish bone caused the secondary appendicitis, and that after the appendectomy, residual actinomyces caused the cutaneous-rectovesical fistula. After the diagnosis, total parenteral nutrition and a long-term administration of antibiotics improved the patient's clinical symptoms, and the fistula closed within a month. Antibiotics were administered for 6 months, and there has been no recurrence for 6-1/2 years. Because actinomycosis is difficult to diagnose based on the typical clinical features, a direct identification of the infecting organism from a tissue sample or from sulfur granules is required for the definitive diagnosis. Actinomyces is also known to cause fistula formation, and intestinal penetration caused by a fish bone may indicate abdominal actinomycosis. A rectovesical fistula requires surgical intervention in most cases, but in cases caused by abdominal actinomycosis, such a fistula may be cured by conservative therapy, as in our patient's case. It is important to consider the possibility of actinomycosis when a refractory rectovesical fistula is observed.
キーワード 放線菌症 (actinomycosis) 皮膚直腸膀胱瘻 (cutaneous-rectovesical fistula) 急性虫垂炎 (appendicitis)
出版物タイトル 岡山医学会雑誌
発行日 2017-04-03
129巻
1号
開始ページ 35
終了ページ 39
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2017 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.129.35
NAID 130005632060
著者 Iwamuro, Masaya| Urata, Haruo| Tanaka, Takehiro| Ando, Akemi| Nada, Takahiro| Kimura, Kosuke| Yamauchi, Kenji| Kusumoto, Chiaki| Otsuka, Fumio| Okada, Hiroyuki|
発行日 2017-02
出版物タイトル Acta Medica Okayama
71巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/54828
著者 小林 勝弘|
発行日 2016-12-01
出版物タイトル 岡山医学会雑誌
128巻
3号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/54504
フルテキストURL 70_4_279.pdf
著者 Nishimura, Yoshito| Iwamuro, Masaya| Ocho, Kazuki| Hasegawa, Kou| Kimura, Kosuke| Hanayama, Yoshihisa| Kondo, Eisei| Tanaka, Takehiro| Otsuka, Fumio|
抄録 A 61-year-old Japanese man with IgG4-related autoimmune pancreatitis was referred to our hospital because of perspiration during food intake. Abdominal computed tomography (CT) with contrast media revealed multiple mesenteric lymphadenopathies. An open surgical abdominal biopsy and subsequent histopathological analysis revealed abnormally large lymphoid cells that were negative for CD3, CD5, and c-myc and positive for CD20 and bcl-2, leading to a diagnosis of diffuse large B-cell lymphoma. Here, we discuss the risk of malignancies, particularly malignant lymphoma in patients with IgG4-related disease. The importance of pathological analysis to reach the appropriate diagnosis in such cases should be emphasized.
キーワード IgG4-related disease autoimmune pancreatitis immunophenotyping diffuse large B-cell lymphoma
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2016-08
70巻
4号
出版者 Okayama University Medical School
開始ページ 279
終了ページ 283
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 27549673
Web of Science KeyUT 000384748600008
JaLCDOI 10.18926/AMO/54422
フルテキストURL 70_3_217.pdf
著者 Waseda, Koichi| Ocho, Kazuki| Hasegawa, Kou| Kimura, Kosuke| Iwamuro, Masaya| Hanayama, Yoshihisa| Kondo, Eisei| Miyahara, Nobuaki| Otsuka, Fumio|
抄録 KL-6 is a glycoprotein found predominantly on type II pneumocytes and alveolar macrophages, and often shows increased serum levels in patients with interstitial pneumonia. We report a case of mycobacterium avium complex (MAC) infection whose disease activity was correlated with KL-6 levels in serum. During treatment of rheumatoid arthritis (RA)-associated interstitial lung disease (ILD) with prednisolone, chest image findings improved in association with decreased KL-6 levels. Following tapering of prednisolone, chest image findings deteriorated again as levels of KL-6 increased, suggesting recurrence of RA-ILD. Bronchoscopic examination revealed active MAC infection. Treatment of MAC infection not only improved chest image findings but also decreased KL-6 levels in serum, suggesting that KL-6 was increased by active MAC infection by itself, not by recurrence of RA-ILD. To the best of our knowledge, this is the first documentation of KL-6 elevation in serum in association with active MAC infection.
キーワード KL-6 mycobacterium avium complex pulmonary nontuberculous mycobacterium infection rheumatoid arthritis-associated interstitial lung disease bronchial alveolar lavage
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2016-06
70巻
3号
出版者 Okayama University Medical School
開始ページ 217
終了ページ 221
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 27339212
Web of Science KeyUT 000379406100010
JaLCDOI 10.18926/OER/54167
タイトル(別表記) The Empirical Analysis of Energy Efficiency in Japanese Manufacturing Industries: The Impact of Industrial Agglomeration on Energy Efficiency
フルテキストURL oer_047_3_185_207.pdf
著者 大塚 章弘|
出版物タイトル 岡山大学経済学会雑誌
発行日 2016-03-19
47巻
3号
開始ページ 185
終了ページ 207
ISSN 0386-3069
言語 日本語
著作権者 Copyright © 2016 岡山大学経済学会
論文のバージョン publisher
NAID 120005740505
フルテキストURL O0004452_abstract_review.pdf O0004452_fulltext.pdf
著者 大塚 正樹|
発行日 2015-12-31
資料タイプ 学位論文
学位授与番号 乙第4452号
学位授与年月日 2015-12-31
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
タイトル(別表記) A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection
フルテキストURL 127_213.pdf
著者 安井 和也| 楳田 祐三| 熊野 健二郎| 田端 雅弘| 大塚 文男| 八木 孝仁| 藤原 俊義|
抄録 A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs.
キーワード 異所性褐色細胞腫(ectopic pheochromocytoma) 化学療法(chemo therapy) 131I-MIBG
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
開始ページ 213
終了ページ 218
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.213
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.213
NAID 130005116814
JaLCDOI 10.18926/AMO/53679
フルテキストURL 69_5_319.pdf
著者 Hagiya, Hideharu| Iwamuro, Masaya| Tanaka, Takehiro| Hanayama, Yoshihisa| Otsuka, Fumio|
抄録 A 60-year-old woman with rheumatoid arthritis treated with methotrexate for a decade complained of slight epigastric discomfort. A positive cytomegalovirus (CMV) antigenemia test indicated the probability of CMV-related gastrointestinal infection, for which esophagogastroduodenoscopy was performed. Endoscopic findings showed a non-specific duodenal mucosal lesion;however, pathological investigation revealed evidence of CMV duodenitis. There is scarce information on the clinical and pathological features of CMV-related duodenitis, likely due to its low prevalence. CMV infection in the upper gastrointestinal tract should be considered as a differential diagnosis in high-risk individuals, particularly those with symptoms relating to the digestive system. Biopsy examinations are preferable for the definitive diagnosis of CMV gastrointestinal infection, even without specific endoscopic features.
キーワード antigenemia cytomegalovirus (CMV) gastrointestinal infection methotrexate opportunistic infection
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-10
69巻
5号
出版者 Okayama University Medical School
開始ページ 319
終了ページ 323
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26490030
Web of Science KeyUT 000365519600009
フルテキストURL K0005135_abstract_review.pdf K0005135_summary.pdf K0005135_fulltext.pdf
著者 大塚 恵理|
発行日 2015-03-25
資料タイプ 学位論文
学位授与番号 甲第5135号
学位授与年月日 2015-03-25
学位・専攻分野 博士(歯学)
授与大学 岡山大学
言語 日本語
JaLCDOI 10.18926/AMO/53342
フルテキストURL 69_2_123.pdf
著者 Waseda, Koichi| Hagiya, Hideharu| Hanayama, Yoshihisa| Terasaka, Tomohiro| Kimura, Kosuke| Tsuzuki, Takao| Hasegawa, Kou| Nada, Takahiro| Nakamura, Eri| Murakami, Kazutoshi| Kondo, Eisei| Otsuka, Fumio|
抄録 An 81-year-old Japanese male with primary Sjögren syndrome (pSS) developed a low-grade fever and productive cough which were refractory to antibiotic therapy. Based on the high level of eosinophils observed in his bronchial alveolar lavage, he was diagnosed with chronic eosinophilic pneumonia (CEP) and successfully treated by oral prednisolone. Interstitial lung diseases associated with pSS (pSS-ILDs) usually present as nonspecific interstitial pneumonia or usual interstitial pneumonia; therefore, the present case is extremely unique in that the patientʼs condition was complicated with CEP. A diagnosis of advanced gallbladder cancer was made in the patientʼs clinical course, suggesting the advisability of a whole-body workup in cases of pSS, especially in elderly patients.
キーワード bronchial alveolar lavage eosinophilic pneumonia eosinophilia interstitial lung diseases Sjögren syndrome
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 123
終了ページ 127
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899635
Web of Science KeyUT 000353181700008
JaLCDOI 10.18926/AMO/53341
フルテキストURL 69_2_119.pdf
著者 Terasaka, Tomohiro| Hagiya, Hideharu| Kimura, Kosuke| Nada, Takahiro| Nakamura, Eri| Hanayama, Yoshihisa| Sugiyama, Hitoshi| Kobayashi, Yasuyuki| Yanai, Hiroyuki| Otsuka, Fumio|
抄録 We report the case of a 46-year-old hypertensive Japanese female with renal insufficiency related to unilateral renal hypoplasia. The patient was found to have developed paraganglioma in the retroperitoneal space over a 5-year period. Catecholamine-producing tumors are not usually recognized as conditions associated with renal hypoplasia. Our long-term observation of the patient eventually led us to the diagnosis of paraganglioma. In hypertensive patients with chronic kidney disease, not only the renin-angiotensin-aldosterone system but also catecholamine activity may be involved, particularly in the patients whose cases are complicated with unilateral renal hypoplasia.
キーワード catecholamine paraganglioma renal hypoplasia renovascular hypertension secondary hypertension
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-04
69巻
2号
出版者 Okayama University Medical School
開始ページ 119
終了ページ 122
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25899634
Web of Science KeyUT 000353181700007