result 312 件
| JaLCDOI | 10.18926/AMO/63746 |
|---|---|
| FullText URL | 76_3_343.pdf |
| Author | Maki, Yuho| Kiriyama, Yosuke| Ueno, Tsuyoshi| Suehisa, Hiroshi| Shigematsu, Hisayuki| Saeki, Kazuhiko| Harada, Daijiro| Kozuki, Toshiyuki| Teramoto, Norihiro| Yamashita, Motohiro| |
| Abstract | Localized malignant mesothelioma is a rare disease and little is known about its treatment strategy. We herein report a case of localized malignant pleural mesothelioma that had infiltrated into the anterior mediastinum, which was successfully treated using chemotherapy and conversion surgery. A 63-year-old man with a mediastinal tumor was referred to our hospital. Pathologic analysis of the biopsy specimen showed malignant mesothelioma. Significant tumor shrinkage by cisplatin and pemetrexed was observed and he underwent radical surgery via a median sternotomy. The patient has been disease free for 12 months. |
| Keywords | localized mesothelioma mediastinum cisplatin pemetrexed conversion surgery |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-06 |
| Volume | volume76 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 343 |
| End Page | 347 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35790367 |
| Web of Science KeyUT | 000823568300015 |
| JaLCDOI | 10.18926/AMO/63718 |
|---|---|
| FullText URL | 76_3_247.pdf |
| Author | Yoshida, Shohei| Fujii, Nobuharu| Kamoi, Chihiro| Kitamura, Wataru| Fujiwara, Hideaki| Asada, Noboru| Nishimori, Hisakazu| Fujii, Keiko| Matsuoka, Ken-ichi| Maeda, Yoshinobu| |
| Abstract | Vaccine-preventable disease (VPD) infections are more severe in immunocompromised hosts. Vaccination against measles, mumps, rubella, and varicella zoster (VZV) (MMRV) is therefore recommended for hematopoietic stem cell transplantation (HCT) recipients. However, studies on adult HCT recipients with VPD infections are limited. At our institution, we have systematically conducted serological MMRV tests as a part of check-up examinations during long-term follow-up (LTFU) after HCT since 2015. This retrospective study aimed to evaluate changes in the serostatus between before and 2 years after allogeneic HCT. Among 161 patients, the pre-transplant seropositivity was 82.7% for measles, 86.8% for mumps, 84.2% for rubella, and 94.3% for VZV. Among 56 patients who underwent LTFU including serological MMRV tests at 2 years after HCT, the percentages maintaining seroprotective antibody levels for measles, mumps, rubella and VZV were 71.5% (40/56), 51.8% (29/56), 48.2% (27/56), and 60.7% (34/56), respectively. Vaccination was recommended for 22 patients, and 12 were vaccinated. Among the 12 vaccinated patients, rates of seroconversion were examined in 2-6 patients for each of the four viruses. They were 100% (3/3) for measles, 33.3% (1/3) for mumps, 50% (3/6) for rubella, and 0% (0/2) for VZV. Further studies are warranted to clarify the effect of vaccination in adult HCT recipients. |
| Keywords | vaccine-preventable disease vaccination allogeneic hematopoietic stem cell transplantation adult |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-06 |
| Volume | volume76 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 247 |
| End Page | 253 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35790354 |
| Web of Science KeyUT | 000823568300003 |
| FullText URL | K0006571_abstract_review.pdf K0006571_summary.pdf K0006571_fulltext.pdf |
|---|---|
| Author | Takase, Ryosuke| |
| Published Date | 2022-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6571号 |
| Granted Date | 2022-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sukegawa, Shintaro| Shimizu, Rieko| Sukegawa, Yuka| Hasegawa, Kazuaki| Ono, Sawako| Fujimura, Ai| Yamamoto, Izumi| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
| Keywords | retrospective cohort study endoscope endodontic surgery prognostic factors |
| Published Date | 2022-05-07 |
| Publication Title | Materials |
| Volume | volume15 |
| Issue | issue9 |
| Publisher | MDPI |
| Start Page | 3353 |
| ISSN | 1996-1944 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35591687 |
| DOI | 10.3390/ma15093353 |
| Web of Science KeyUT | 000794818400001 |
| Related Url | isVersionOf https://doi.org/10.3390/ma15093353 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sukegawa, Shintaro| Fujimura, Ai| Taguchi, Akira| Yamamoto, Norio| Kitamura, Akira| Goto, Ryosuke| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
| Published Date | 2022-04-12 |
| Publication Title | Scientific Reports |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 6088 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 35413983 |
| DOI | 10.1038/s41598-022-10150-x |
| Web of Science KeyUT | 000782202600026 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-10150-x |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Soejima, Yoshiaki| Otsuka, Yuki| Tokumasu, Kazuki| Nakano, Yasuhiro| Harada, Ko| Nakamoto, Kenta| Sunada, Naruhiko| Sakurada, Yasue| Hasegawa, Kou| Hagiya, Hideharu| Ueda, Keigo| Otsuka, Fumio| |
| Keywords | general fatigue free testosterone late-onset hypogonadism long COVID post-COVID condition |
| Published Date | 2022-04-13 |
| Publication Title | Medicina-Lithuania |
| Volume | volume58 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 536 |
| ISSN | 1010-660X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35454374 |
| DOI | 10.3390/medicina58040536 |
| Web of Science KeyUT | 000785092200001 |
| Related Url | isVersionOf https://doi.org/10.3390/medicina58040536 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takahashi, Misa| Hagiya, Hideharu| Higashionna, Tsukasa| Nakano, Yasuhiro| Sato, Kota| Haruki, Yuto| Haruki, Mai| Honda, Hiroyuki| Ogawa, Hiroko| Ueda, Keigo| Otsuka, Fumio| |
| Published Date | 2022-04-08 |
| Publication Title | Scientific Reports |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 5921 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 35396378 |
| DOI | 10.1038/s41598-022-09946-8 |
| Web of Science KeyUT | 000781895600057 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-09946-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Koichiro| Nakano, Yasuhiro| Tokumasu, Kazuki| Honda, Hiroyuki| Hasegawa, Kou| Sato, Asuka| Ogawa, Hiroko| Obika, Mikako| Hanayama, Yoshihisa| Otsuka, Fumio| |
| Keywords | cinacalcct evocalcet hypercalccmia primary hyperparathyroidism |
| Published Date | 2022-04-08 |
| Publication Title | Clinical Case Reports |
| Volume | volume10 |
| Issue | issue4 |
| Publisher | Wiley |
| Start Page | e05713 |
| ISSN | 2050-0904 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Authors. |
| File Version | publisher |
| PubMed ID | 35425612 |
| DOI | 10.1002/ccr3.5713 |
| Web of Science KeyUT | 000781095000001 |
| Related Url | isVersionOf https://doi.org/10.1002/ccr3.5713 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Yukichika| Otsuka, Yuki| Sunada, Naruhiko| Tokumasu, Kazuki| Nakano, Yasuhiro| Honda, Hiroyuki| Sakurada, Yasue| Hagiya, Hideharu| Hanayama, Yoshihisa| Otsuka, Fumio| |
| Keywords | fatigue hypogonadism LOH syndrome long COVID testosterone |
| Published Date | 2022-03-31 |
| Publication Title | Journal Of Clinical Medicine |
| Volume | volume11 |
| Issue | issue7 |
| Publisher | MDPI |
| Start Page | 1955 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35407562 |
| DOI | 10.3390/jcm11071955 |
| Web of Science KeyUT | 000782056600001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm11071955 |
| JaLCDOI | 10.18926/AMO/63409 |
|---|---|
| FullText URL | 76_2_155.pdf |
| Author | Kimura, Jiro| Okabayashi, Takehiro| Sui, Kenta| Tabuchi, Motoyasu| Iwata, Jun| Hata, Yasuhiro| Iiyama, Tatsuo| Ono, Noriaki| |
| Abstract | Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone treatment, including 1 patient from our clinic. We extracted patient characteristics, treatment, and prognostic data, resulting in clinicopathological data on 100 patients (83 men, 17 women). Mean age was 63 years (range, 16-86 years). Tumor sites were duodenum, jejunum, ileum, and multiple sites in 30, 37, 25, and 7 patients, respectively. The 1-, 3-, and 5-year overall survival rates after diagnosis were 53.0%, 36.0%, and 36.0%. Curative resection patients showed 62.1% 5-year survival after surgery, vs. 27.5% in noncurative surgical management cases. Good prognoses can be expected if these tumors are identified early for complete removal. Surgery is the only curative option. To determine the best management strategy and improve prognostic accuracy, we continue to collect and analyze epidemiological and pathological data. Although this condition is rare, surgery should be considered if curative resection is expected. Prognosis after curative resection is not poor, but recurrence is not unlikely. |
| Keywords | renal cell carcinoma small bowel metastasis intestine tumor |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-04 |
| Volume | volume76 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 155 |
| End Page | 165 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35503443 |
| Web of Science KeyUT | 000792374900007 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Inagaki, Junko| Nakano, Airi| Hatipoglu, Omer Faruk| Ooka, Yuka| Tani, Yurina| Miki, Akane| Ikemura, Kentaro| Opoku, Gabriel| Ando, Ryosuke| Kodama, Shintaro| Ohtsuki, Takashi| Yamaji, Hirosuke| Yamamoto, Shusei| Katsuyama, Eri| Watanabe, Shogo| Hirohata, Satoshi| |
| Keywords | osteoarthritis matrix metalloproteinase MMP13 ADAMTS9 expression screening chondrocytes |
| Published Date | 2022-02-28 |
| Publication Title | International Journal Of Molecular Sciences |
| Volume | volume23 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 2681 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35269821 |
| DOI | 10.3390/ijms23052681 |
| Web of Science KeyUT | 000773522200001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms23052681 |
| FullText URL | fulltext20220413-8.pdf figure20220413-8.pdf |
|---|---|
| Author | Bian, Zhihong| Liu, Xia| Feng, Tian| Yu, Haibo| Hu, Xiao| Hu, Xinran| Bian, Yuting| Sun, Hongming| Tadokoro, Koh| Takemoto, Mami| Yunoki, Taijun| Nakano, Yumiko| Fukui, Yusuke| Morihara, Ryuta| Abe, Koji| Yamashita, Toru| |
| Keywords | Alzheimer’s disease cerebral amyloid angiopathy chronic cerebral hypoperfusion rivaroxaban warfarin |
| Note | This is an Accepted Manuscript of an article published by IOS Press. available online: https://doi.org/10.3233/jad-215318| |
| Published Date | 2022-3-8 |
| Publication Title | Journal of Alzheimer's Disease |
| Volume | volume86 |
| Issue | issue1 |
| Publisher | IOS Press |
| Start Page | 111 |
| End Page | 123 |
| ISSN | 1387-2877 |
| NCID | AA11545428 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright ©2022 IOS Press All rights reserved. |
| File Version | author |
| PubMed ID | 35001892 |
| DOI | 10.3233/jad-215318 |
| Web of Science KeyUT | 000768536700003 |
| Related Url | isVersionOf https://doi.org/10.3233/jad-215318 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakurada, Yasue| Sunada, Naruhiko| Honda, Hiroyuki| Tokumasu, Kazuki| Otsuka, Yuki| Nakano, Yasuhiro| Hanayama, Yoshihisa| Furukawa, Masanori| Hagiya, Hideharu| Otsuka, Fumio| |
| Keywords | Anti-SARS-CoV2 antibody dysgeusia dysosmia general fatigue long COVID |
| Published Date | 2022-02-27 |
| Publication Title | Journal Of Clinical Medicine |
| Volume | volume11 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 1309 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35268400 |
| DOI | 10.3390/jcm11051309 |
| Web of Science KeyUT | 000768542800001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm11051309 |
| FullText URL | fulltext20220309-3.pdf figure-3.pdf |
|---|---|
| Author | Morihara, Ryuta| Yamashita, Toru| Deguchi, Kentaro| Kurata, Tomoko| Nomura, Emi| Sato, Kota| Nakano, Yumiko| Ohta, Yasuyuki| Hishikawa, Nozomi| Ikeuchi, Takeshi| Kitaguchi, Masataka| Abe, Koji| |
| Keywords | parietal ataxia parietal lobe atrophy crossed cerebellar diaschisis MAPT |
| Note | © 2018 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jns.2018.01.031] .| |
| Published Date | 2018-4 |
| Publication Title | Journal of the Neurological Sciences |
| Volume | volume387 |
| Issue | issue15 |
| Publisher | Elsevier BV |
| Start Page | 70 |
| End Page | 74 |
| ISSN | 0022-510X |
| NCID | AA00703265 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2018 Elsevier B.V. |
| File Version | author |
| DOI | 10.1016/j.jns.2018.01.031 |
| Web of Science KeyUT | 000430775700011 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jns.2018.01.031 |
| Title Alternative | Downregulation of PAR-1 and PAR-2 by Rivaroxaban |
|---|---|
| FullText URL | fulltext20220309-4.pdf Figure20220309-4.pdf |
| Author | Morihara, Ryuta| Yamashita, Toru| Kono, Syoichiro| Shang, Jingwei| Nakano, Yumiko| Sato, Kota| Hishikawa, Nozomi| Ohta, Yasuyuki| Heitmeier, Stefan| Perzborn, Elisabeth| Abe, Koji| |
| Keywords | PAR-3 PAR-4 tissue plasminogen activator warfarin |
| Note | This is the peer reviewed version of the following article: [Morihara, R., Yamashita, T., Kono, S., Shang, J., Nakano, Y., Sato, K., Hishikawa, N., Ohta, Y., Heitmeier, S., Perzborn, E. and Abe, K. (2017), Reduction of intracerebral hemorrhage by rivaroxaban after tPA thrombolysis is associated with downregulation of PAR-1 and PAR-2. Journal of Neuroscience Research, 95: 1818-1828. https://doi.org/10.1002/jnr.24013], which has been published in final form at [https://doi.org/10.1002/jnr.24013]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2016-12-30 |
| Publication Title | Journal of Neuroscience Research |
| Volume | volume95 |
| Issue | issue9 |
| Publisher | Wiley |
| Start Page | 1818 |
| End Page | 1828 |
| ISSN | 0360-4012 |
| NCID | AA00703378 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©2016 Wiley Periodicals, Inc. |
| File Version | author |
| DOI | 10.1002/jnr.24013 |
| Web of Science KeyUT | 000427450300275 |
| Related Url | isVersionOf https://doi.org/10.1002/jnr.24013 |
| FullText URL | fulltext20220308-2.pdf |
|---|---|
| Author | Morihara, Ryuta| Yamashita, Toru| Deguchi, Kentaro| Tsunoda, Keiichiro| Manabe, Yasuhiro| Takahashi, Yoshiaki| Yunoki, Taijun| Sato, Kota| Nakano, Yumiko| Kono, Syoichiro| Ohta, Yasuyuki| Hishikawa, Nozomi| Abe, Koji| |
| Note | Internal Medicine, 2017, 56(17), 2343-2346| |
| Published Date | 2017-09-01 |
| Publication Title | Internal Medicine |
| Volume | volume56 |
| Issue | issue17 |
| Publisher | Japanese Society of Internal Medicine |
| Start Page | 2343 |
| End Page | 2346 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2017 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 28794365 |
| DOI | 10.2169/internalmedicine.8438-16 |
| Web of Science KeyUT | 000411760900019 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.8438-16 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ishida, Tomoharu| Hagiya, Hideharu| Honda, Hiroyuki| Nakano, Yasuhiro| Ogawa, Hiroko| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Hanayama, Yoshihisa| Otsuka, Fumio| |
| Published Date | 2021-11-12 |
| Publication Title | Plos One |
| Volume | volume16 |
| Issue | issue11 |
| Publisher | Public Library Science |
| Start Page | e0259633 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Ishida et al. |
| File Version | publisher |
| PubMed ID | 34767587 |
| DOI | 10.1371/journal.pone.0259633 |
| Web of Science KeyUT | 000755249300037 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0259633 |
| JaLCDOI | 10.18926/AMO/63215 |
|---|---|
| FullText URL | 76_1_79.pdf |
| Author | Tokumoto, Kana| Mino, Takuya| Kurosaki, Yoko| Izumi, Koji| Maekawa, Kenji| Nakano, Tomohito| Sejima, Junichi| Ueda, Akihiro| Kimura-Ono, Aya| Hyung Kim, Tae| Kuboki, Takuo| |
| Abstract | We introduce a new digital workflow to fabricate a fixed partial denture (FPD) utilizing the three-dimensional surface morphology of provisional restoration (PR) and abutment teeth. Scanned images of the full maxilla with abutment teeth, full maxilla with PR, and PR alone were superimposed. The surfaces of the final FPD were designed based on the entire morphology of the PR and abutment teeth surfaces. The inner and outer surfaces converged at the margin lines of the abutment teeth. Fine modifications to the final FPD design were performed manually, and the final FPD was fabricated and successfully installed in the patient. |
| Keywords | prosthodontics computer-aided design digital dentistry fixed partial denture dental restoration |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 79 |
| End Page | 84 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237002 |
| Web of Science KeyUT | 000762803800002 |
| FullText URL | fulltext20220222-2.pdf |
|---|---|
| Author | Kawashima, Takeshi| Yoshida, Masa-aki| Miyazawa, Hideyuki| Nakano, Hiroaki| Nakano, Natumi| Sakamoto, Tatsuya| Hamada, Mayuko| |
| Keywords | eDNA marine invertebrate Xenacoelomorpha Acoela Praesagittifera naikaiensis Placozoa Trichoplax adhaerens |
| Note | This fulltext is published by Zoological Society of Japan. To access the final published work, see https://doi.org/10.2108/zs210073 .| This full-text file will be available in Feb. 2023.| |
| Published Date | 2022-01-28 |
| Publication Title | Zoological Science |
| Volume | volume39 |
| Issue | issue1 |
| Publisher | Zoological Society of Japan |
| Start Page | 157 |
| End Page | 165 |
| ISSN | 0289-0003 |
| NCID | AA10545874 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Zoological Society of Japan |
| File Version | publisher |
| PubMed ID | 35107003 |
| DOI | 10.2108/zs210073 |
| Web of Science KeyUT | 000752098100015 |
| Related Url | isVersionOf https://doi.org/10.2108/zs210073 |
| JaLCDOI | 10.18926/AMO/63203 |
|---|---|
| FullText URL | 76_1_7.pdf |
| Author | Takami, Masao| Yamamoto, Koichiro| Hanayama, Yoshihisa| Nakano, Yasuhiro| Hasegawa, Kou| Obika, Mikako| Hagiya, Hideharu| Furukawa, Masanori| Otsuka, Fumio| |
| Abstract | Subclinical hypothyroidism (SCH) is diagnosed when serum thyrotropin (TSH) is elevated despite a normal thyroxine level and is known to increase the risk of metabolic disorders. This study was conducted to identify potential laboratory markers suspicious for latent SCH. We retrospectively reviewed 958 outpatients in whom thyroid functions had been examined. Eighty-five (9.1%) of the 939 analyzed subjects had SCH (73% females). In the SCH group, median serum TSH and FT4 levels were 5.04 μU/ml and 1.19 ng/dl, respectively, and auto-thyroid antibodies were detected in 53.8% of patients. SCH group patients were significantly older than patients in the euthyroid group, while there was no intergroup difference in BMI. However, 56.5% of the SCH patients were asymptomatic. In the SCH group, serum aspartate aminotransferase and low-density lipoprotein cholesterol (LDL-C) levels were significantly higher, and the estimated glomerular filtration rate (eGFR) was significantly lower than in the euthyroid group. Among patients less than 65 years of age, SCH patients tended to have lower eGFR and higher LDL-C than euthyroid patients. Age-dependent reductions of red blood cells and serum albumin were more prominent in the SCH than the euthyroid group. Biochemical changes with aging are useful as potential clues for suspecting latent SCH. |
| Keywords | aging renal function cholesterol subclinical hypothyroidism thyroid function |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 7 |
| End Page | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35236993 |
| Web of Science KeyUT | 000762812700002 |
