result 321 件
| FullText URL | K0007002_abstract_review.pdf K0007002_fulltext.pdf |
|---|---|
| Author | SUNADA, Naruhiko| |
| Published Date | 2024-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第7002号 |
| Granted Date | 2024-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2022 by the authors. |
| FullText URL | K0007001_abstract_review.pdf K0007001_fulltext.pdf K0007001_summary.pdf |
|---|---|
| Author | SOEJIMA, Yoshiaki| |
| Published Date | 2024-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第7001号 |
| Granted Date | 2024-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023 by the authors. |
| FullText URL | K0006993_abstract_review.pdf K0006993_summary.pdf K0006993_fulltext.pdf K0006993_other.pdf |
|---|---|
| Author | SUYAMA, Atsuhito| |
| Published Date | 2024-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6993号 |
| Granted Date | 2024-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © The Japan Endocrine Society |
| FullText URL | fulltext20240512-01.pdf |
|---|---|
| Author | Zhai, Yun| Morihara, Ryuta| Feng, Tian| Hu, Xinran| Fukui, Yusuke| Bian, Zhihong| Bian, Yuting| Yu, Haibo| Sun, Hongming| Takemoto, Mami| Nakano, Yumiko| Yunoki, Taijun| Tang, Ying| Ishiura, Hiroyuki| Yamashita, Toru| |
| Keywords | Alzheimer's disease Hypoperfusion Cerebral vascular remodeling Scallop-derived plasmalogen pSTAT3/PIM1/NFATc1 axis |
| Note | © 2024 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jan. 2025.| |
| Published Date | 2024-04-01 |
| Publication Title | Brain Research |
| Volume | volume1828 |
| Publisher | Elsevier BV |
| Start Page | 148790 |
| ISSN | 0006-8993 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Elsevier B.V. |
| File Version | author |
| PubMed ID | 38272156 |
| DOI | 10.1016/j.brainres.2024.148790 |
| Web of Science KeyUT | 001173928400001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.brainres.2024.148790 |
| JaLCDOI | 10.18926/AMO/66927 |
|---|---|
| FullText URL | 78_2_185.pdf |
| Author | Takahashi, Hiroko| Eguchi, Jun| Watanabe, Mayu| Nakayama, Masanori| Wada, Jun| |
| Abstract | The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients. |
| Keywords | obesity type 2 diabetes COVID-19 vaccination |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-04 |
| Volume | volume78 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 185 |
| End Page | 191 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38688836 |
| Web of Science KeyUT | 001227932200002 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Oguni, Kohei| Yamamoto, Koichiro| Nakano, Yasuhiro| Soejima, Yoshiaki| Suyama, Atsuhito| Takase, Ryosuke| Yasuda, Miho| Hasegawa, Kou| Otsuka, Fumio| |
| Keywords | acromegaly growth hormone (GH) GH deficiency (GHD) insulin-like growth factor (IGF)-I pituitary gland |
| Published Date | 2024-03-26 |
| Publication Title | Frontiers in Endocrinology |
| Volume | volume15 |
| Publisher | Frontiers Media |
| Start Page | 1381083 |
| ISSN | 1664-2392 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Oguni, Yamamoto, Nakano, Soejima, Suyama, Takase, Yasuda, Hasegawa and Otsuka. |
| File Version | publisher |
| PubMed ID | 38596224 |
| DOI | 10.3389/fendo.2024.1381083 |
| Web of Science KeyUT | 001198436000001 |
| Related Url | isVersionOf https://doi.org/10.3389/fendo.2024.1381083 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakano, Yasuhiro| Sunada, Naruhiko| Tokumasu, Kazuki| Honda, Hiroyuki| Otsuka, Yuki| Sakurada, Yasue| Matsuda, Yui| Hasegawa, Toru| Omura, Daisuke| Ochi, Kanako| Yasuda, Miho| Hagiya, Hideharu| Ueda, Keigo| Otsuka, Fumio| |
| Keywords | Diabetes mellitus Endocrine disorders Long COVID Metabolic disorders Thyroid disease |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55526-3| |
| Published Date | 2024-03-05 |
| Publication Title | Scientific Reports |
| Volume | volume14 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 5446 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| PubMed ID | 38443459 |
| DOI | 10.1038/s41598-024-55526-3 |
| Web of Science KeyUT | 001180457200009 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-024-55526-3 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kadoya, Koichi| Hara, Emilio Satoshi| Okada, Masahiro| Jiao, Yu Yang| Nakano, Takayoshi| Sasaki, Akira| Matsumoto, Takuya| |
| Keywords | trabecular bone calcospherites cell membrane nano fragments three dimensionalization bone tissue synthesis |
| Published Date | 2022-11-02 |
| Publication Title | Regenerative Biomaterials |
| Volume | volume10 |
| Publisher | Oxford University Press |
| Start Page | rbac088 |
| ISSN | 2056-3418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. |
| File Version | publisher |
| PubMed ID | 36683756 |
| DOI | 10.1093/rb/rbac088 |
| Web of Science KeyUT | 001187808700008 |
| Related Url | isVersionOf https://doi.org/10.1093/rb/rbac088 |
| JaLCDOI | 10.18926/AMO/66674 |
|---|---|
| FullText URL | 78_1_079.pdf |
| Author | Takahara, Masahiro| Hiraoka, Sakiko| Ohmori, Masayasu| Takeuchi, Keiko| Takei, Kensuke| Aoyama, Yuki| Yasutomi, Eriko| Igawa, Shoko| Inokuchi, Toshihiro| Toyosawa, Junki| Yamasaki, Yasushi| Kinugasa, Hideaki| Harada, Keita| Onishi, Hideki| Okada, Hiroyuki| |
| Abstract | This study examined the utility of the combined use of transabdominal ultrasonography (TUS) and fecal immunochemical testing (FIT) to detect mucosal inflammation, vis-a-vis the Mayo endoscopic subscore (MES), in ulcerative colitis (UC). Sixty-three UC patients who underwent TUS and FIT were retrospectively enrolled. For TUS, the colon was divided into five segments, and the bowel wall thickness was measured and evaluated. The accuracy of FIT (> 100 ng/ml) in detecting mucosal inflammation (MES>0) was 0.93, whereas that of TUS (BWT>2 mm) in each segment was 0.84-0.97. The combined use of TUS and FIT may be helpful in noninvasive treatment strategies. |
| Keywords | transabdominal ultrasonography fecal immunochemical test ulcerative colitis Mayo endoscopic subscore |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-02 |
| Volume | volume78 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 79 |
| End Page | 83 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38419318 |
| Web of Science KeyUT | 001203658200004 |
| JaLCDOI | 10.18926/AMO/66672 |
|---|---|
| FullText URL | 78_1_063.pdf |
| Author | Murakami, Daizo| Nishimoto, Kohei| Takao, Soshi| Miyamaru, Satoru| Kadowaki, Tomoka| Saito, Haruki| Takeda, Hiroki| Ise, Momoko| Suyama, Koichi| Orita, Yorihisa| |
| Abstract | The tyrosine kinase inhibitor lenvatinib has been confirmed as an effective treatment option for patients with unresectable thyroid carcinoma. We conducted a retrospective analysis of the significance of the effect of continued lenvatinib treatment for the longest duration possible at a reasonable daily dose and with a minimum discontinuation period in 42 patients with unresectable thyroid carcinoma treated with lenvatinib between 2015 and 2020. A Cox proportional hazard model-based analysis revealed that the overall survival of the patients treated with a <8 mg/day mean dose of lenvatinib was significantly better than that of the patients treated with 8-24 mg/day (hazard ratio [HR] 0.38 for 1.14-4.54 mg/day, and HR 0.01 for 4.56-7.97 mg/day) adjusted for various factors (e.g., sex, age, drug interruption period). The cumulative dose of lenvatinib administered tended to be higher in the patients treated with low doses (< 8 mg/day) than in the patients treated with relatively high doses (8-24 mg/day). Considering its adverse events, the continuation of lenvatinib treatment with an adequate daily dose and drug interruption may help prolong the survival of patients with unresectable thyroid carcinoma. |
| Keywords | thyroid carcinoma lenvatinib adverse effect survival |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-02 |
| Volume | volume78 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 63 |
| End Page | 70 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38419316 |
| Web of Science KeyUT | 001203658200007 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Soejima, Yoshiaki| Iwata, Nahoko| Yamamoto, Koichiro| Suyama, Atsuhito| Nakano, Yasuhiro| Otsuka, Fumio| |
| Keywords | bone morphogenetic protein (BMP) orexin catecholamine and adrenal |
| Published Date | 2024-01-27 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume25 |
| Issue | issue3 |
| Publisher | MDPI |
| Start Page | 1585 |
| ISSN | 1661-6596 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 by the authors. |
| File Version | publisher |
| PubMed ID | 38338864 |
| DOI | 10.3390/ijms25031585 |
| Web of Science KeyUT | 001160350600001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms25031585 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sakurada, Yasue| Matsuda, Yui| Motohashi, Kanon| Hasegawa, Toru| Otsuka, Yuki| Nakano, Yasuhiro| Tokumasu, Kazuki| Yamamoto, Koichiro| Sunada, Naruhiko| Honda, Hiroyuki| Hagiya, Hideharu| Ueda, Keigo| Otsuka, Fumio| |
| Keywords | Depression fatigue menstrual symptoms omicron variant post-COVID-19 condition |
| Published Date | 2024-01-25 |
| Publication Title | Journal of Psychosomatic Obstetrics & Gynecology |
| Volume | volume45 |
| Issue | issue1 |
| Publisher | Taylor and Francis |
| Start Page | 2305899 |
| ISSN | 0167-482X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Author(s). |
| File Version | publisher |
| PubMed ID | 38270210 |
| DOI | 10.1080/0167482X.2024.2305899 |
| Web of Science KeyUT | 001148717900001 |
| Related Url | isVersionOf https://doi.org/10.1080/0167482X.2024.2305899 |
| FullText URL | fulltext20240304-02.pdf |
|---|---|
| Author | Hagiya, Hideharu| Tokumasu, Kazuki| Otsuka, Yuki| Sunada, Naruhiko| Nakano, Yasuhiro| Honda, Hiroyuki| Furukawa, Masanori| Otsuka, Fumio| |
| Keywords | Complement immunity Complement system Coronavirus disease 2019 Inflammation |
| Note | © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Feb. 2025.| |
| Published Date | 2024-03 |
| Publication Title | Journal of Infection and Chemotherapy |
| Volume | volume30 |
| Issue | issue3 |
| Publisher | Elsevier |
| Start Page | 236 |
| End Page | 241 |
| ISSN | 1341-321X |
| NCID | AA11057978 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. |
| File Version | author |
| PubMed ID | 37866620 |
| DOI | 10.1016/j.jiac.2023.10.016 |
| Web of Science KeyUT | 001167908700001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jiac.2023.10.016 |
| Author | Miura, Kizuku| Fujihara, Michiko| Watanabe, Masaki| Takamura, Yuta| Kawasaki, Mayu| Nakano, Shogo| Kakuta, Hiroki| |
|---|---|
| Keywords | RXR Fluorescence Solvatochromism Binding assay |
| Note | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Nov. 2025.| |
| Published Date | 2023-11-15 |
| Publication Title | Bioorganic & Medicinal Chemistry Letters |
| Volume | volume96 |
| Publisher | Elsevier BV |
| Start Page | 129536 |
| ISSN | 0960-894X |
| NCID | AA1079577X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Elsevier Ltd. |
| File Version | author |
| PubMed ID | 37913851 |
| DOI | 10.1016/j.bmcl.2023.129536 |
| Web of Science KeyUT | 001107680700001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.bmcl.2023.129536 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tadokoro, Koh| Nakada, Yumi| Sasaki, Ryo| Nakano, Yumiko| Yunoki, Taijun| Shin, Kotaro| Taoka, Masataka| Ninomiya, Kiichiro| Nomura, Emi| Takemoto, Mami| Morihara, Ryuta| Yamashita, Toru| |
| Keywords | sarcoidosis myelopathy lung cancer |
| Published Date | 2023-12-01 |
| Publication Title | Internal Medicine |
| Volume | volume62 |
| Issue | issue23 |
| Publisher | Japanese Society of Internal Medicine |
| Start Page | 3531 |
| End Page | 3535 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 37062734 |
| DOI | 10.2169/internalmedicine.0943-22 |
| Web of Science KeyUT | 001115860700001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.0943-22 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Shinoda-Ito, Yuki| Hirai, Anna| Omori, Kazuhiro| Ideguchi, Hidetaka| Yamamoto, Hideki| Kato, Fumino| Obata, Kyoichi| Ogawa, Tatsuo| Nakano, Keisuke| Nakadoi, Takato| Katsuyama, Eri| Ibaragi, Soichiro| Yamamoto, Tadashi| Nagatsuka, Hitoshi| Hirasawa, Akira| Takashiba, Shogo| |
| Keywords | Ligneous periodontitis Plasminogen deficiency PLG Behcet's disease Gingival hyperplasia |
| Note | The version of record of this article, first published in BMC Oral Health, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12903-023-03586-8| |
| Published Date | 2023-11-08 |
| Publication Title | BMC Oral Health |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 843 |
| ISSN | 1472-6831 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37940896 |
| DOI | 10.1186/s12903-023-03586-8 |
| Web of Science KeyUT | 001101860500001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12903-023-03586-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tokumasu, Kazuki| Fujita-Yamashita, Manami| Sunada, Naruhiko| Sakurada, Yasue| Yamamoto, Koichiro| Nakano, Yasuhiro| Matsuda, Yui| Otsuka, Yuki| Hasegawa, Toru| Hagiya, Hideharu| Honda, Hiroyuki| Otsuka, Fumio| |
| Keywords | adverse events COVID-19 SARS-CoV-2 vaccination mRNA vaccine |
| Published Date | 2023-10-30 |
| Publication Title | Vaccines |
| Volume | volume11 |
| Issue | issue11 |
| Publisher | MDPI |
| Start Page | 1661 |
| ISSN | 2076-393X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 38005993 |
| DOI | 10.3390/vaccines11111661 |
| Web of Science KeyUT | 001113977600001 |
| Related Url | isVersionOf https://doi.org/10.3390/vaccines11111661 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamashita, Toru| Nakano, Yumiko| Sasaki, Ryo| Tadokoro, Koh| Omote, Yoshio| Yunoki, Taijun| Kawahara, Yuko| Matsumoto, Namiko| Taira, Yuki| Matsuoka, Chika| Morihara, Ryuta| Abe, Koji| |
| Keywords | amyotrophic lateral sclerosis clinical trial CL2020 multilineage-differentiating stress-enduring (Muse) cells intravenous administration |
| Published Date | 2023 |
| Publication Title | Cell Transplantation |
| Volume | volume32 |
| Publisher | SAGE Publications |
| ISSN | 0963-6897 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 38014622 |
| DOI | 10.1177/09636897231214370 |
| Web of Science KeyUT | 001109624600001 |
| Related Url | isVersionOf https://doi.org/10.1177/09636897231214370 |
| JaLCDOI | 10.18926/AMO/66156 |
|---|---|
| FullText URL | 77_6_635.pdf |
| Author | Ikeda, Tomohiro| Okamura, Kazunori| Hasegawa, Masaki| Tanaka, Satoshi| Kanai, Shusaku| |
| Abstract | In the management of post-injury patients with activity limitations, methods to prevent musculoskeletal disorders and hasten recovery are important. This randomized controlled, single-blinded study was a preliminary investigation of the combined effect of nutritional support with neuromuscular electrical stimulation (NMES) on muscle strength and thickness. Healthy young adult males (median age, 21 years) were enrolled; each of their hands was randomly assigned to one of the following four groups: Placebo, Nutrition, NMES, and Nutrition + NMES. All participants received whey protein or placebo (3x/week for 6 weeks) and NMES training (3x/week for 6 weeks) on the abductor digiti minimi (ADM) muscle of either the left or right hand. ADM muscle strength and thickness were analyzed at baseline and at week 7. We analyzed 38 hands (9 Placebo, 10 Nutrition, 9 NMES, 10 Nutrition + NMES). There was significantly greater muscle strengthening in the Nutrition + NMES group compared to the Placebo group or the NMES group, but no significant difference in gain of muscle thickness. The combined intervention may be effective in improving muscle strength. Future clinical trials targeting various muscles after sports-related injuries are warranted. |
| Keywords | whey protein electrical stimulation muscle strength healthy volunteers |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-12 |
| Volume | volume77 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 635 |
| End Page | 645 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38145938 |
| Web of Science KeyUT | 001164631200009 |
| FullText URL | K0006922_abstract_review.pdf K0006922_fulltext.pdf K0006922_summary.pdf |
|---|---|
| Author | YAMAMOTO, Koichiro| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6922号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023 Elsevier Inc. |
