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Author Khazan, Negar| Kim, Kyu Kwang| Hansen, Jeanne N.| Singh, Niloy A.| Moore, Taylor| Snyder, Cameron W. A.| Pandita, Ravina| Strawderman, Myla| Fujihara, Michiko| Takamura, Yuta| Jian, Ye| Battaglia, Nicholas| Yano, Naohiro| Teramoto, Yuki| Arnold, Leggy A.| Hopson, Russell| Kishor, Keshav| Nayak, Sneha| Ojha, Debasmita| Sharon, Ashoke| Ashton, John M.| Wang, Jian| Milano, Michael T.| Miyamoto, Hiroshi| Linehan, David C.| Gerber, Scott A.| Kawar, Nada| Singh, Ajay P.| Tabdanov, Erdem D.| Dokholyan, Nikolay V.| Kakuta, Hiroki| Jurutka, Peter W.| Schor, Nina F.| Rowswell-Turner, Rachael B.| Singh, Rakesh K.| Moore, Richard G.|
Published Date 2022-04-11
Publication Title Journal of Medicinal Chemistry
Volume volume65
Issue issue8
Publisher American Chemical Society (ACS)
Start Page 6039
End Page 6055
ISSN 0022-2623
NCID AA00702411
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 35404047
DOI 10.1021/acs.jmedchem.1c01878
Web of Science KeyUT 000797573100012
Related Url isVersionOf https://doi.org/10.1021/acs.jmedchem.1c01878
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Author Ono-Minagi, Hitomi| Nohno, Tsutomu| Serizawa, Takashi| Usami, Yu| Sakai, Takayoshi| Okano, Hideyuki| Ohuchi, Hideyo|
Keywords salivary and lacrimal glands development three germ layers neural crest
Published Date 2023-09-05
Publication Title International Journal of Molecular Sciences
Volume volume24
Issue issue18
Publisher MDPI
Start Page 13692
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 37761995
DOI 10.3390/ijms241813692
Web of Science KeyUT 001071736900001
Related Url isVersionOf https://doi.org/10.3390/ijms241813692
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Author Umemori, Koki| Ono, Kisho| Kanemoto, Hideka| Obata, Kyoichi| Kawai, Hotaka| Nakamura, Tomoya| Nakano, Keisuke| Ibaragi, Soichiro| Nagatsuka, Hitoshi| Sasaki, Akira|
Keywords Pleomorphic adenoma (PA) upper lip lower lip minor salivary gland tumor case series
Published Date 2022-10-27
Publication Title Gland Surgery
Volume volume11
Issue issue10
Publisher AME Publishing Company
Start Page 1730
End Page 1740
ISSN 2227-684X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Gland Surgery.
File Version publisher
PubMed ID 36353586
DOI 10.21037/gs-22-308
Web of Science KeyUT 000860255900001
Related Url isVersionOf https://doi.org/10.21037/gs-22-308
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Author Ohmori, Iori| Ouchida, Mamoru| Shinohara, Masakazu| Kobayashi, Kiyoka| Ishida, Saeko| Mashimo, Tomoji|
Keywords animal model combined generalized and focal epilepsy oxidative stress thioredoxin
Published Date 2022-05-28
Publication Title Epilepsia
Volume volume63
Issue issue7
Publisher Wiley
Start Page e80
End Page e85
ISSN 0013-9580
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 35532890
DOI 10.1111/epi.17295
Web of Science KeyUT 000800706600001
Related Url isVersionOf https://doi.org/10.1111/epi.17295
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Author Nakata, Eiji| Kawai, Hotaka| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Inoue, Hirofumi| Futagawa, Mashu| Katayama, Haruyoshi| Itano, Takuto| Ozaki, Toshifumi|
Keywords giant cell tumor of bone malignant transformation p53 denosumab molecular targeted therapy
Published Date 2022-07-19
Publication Title Oncology Letters
Volume volume24
Issue issue3
Publisher Spandidos Publications
Start Page 319
ISSN 1792-1074
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Nakata et al.
File Version publisher
PubMed ID 35949597
DOI 10.3892/ol.2022.13439
Web of Science KeyUT 000840512400001
Related Url isVersionOf https://doi.org/10.3892/ol.2022.13439
FullText URL fulltext20230923-01.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro|
Keywords myxoma orbital CD34 ethmoid sinus literature review
Published Date 2023-09-22
Publication Title Journal of Investigative Medicine High Impact Case Reports
Volume volume11
Publisher SAGE Publications
Start Page 1
End Page 6
ISSN 2324-7096
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 American Federation for Medical Research
File Version publisher
PubMed ID 37737575
DOI 10.1177/23247096231201013
Web of Science KeyUT 001070220300001
Related Url isVersionOf https://doi.org/10.1177/23247096231201013
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Author Matsumoto, Kazuyuki| Ohara, Toshiaki| Fujisawa, Masayoshi| Takaki, Akinobu| Takahara, Masahiro| Kato, Hironari| Yoshida, Ryuichi| Umeda, Yuzo| Yagi, Takahito| Matsukawa, Akihiro| Okada, Hiroyuki|
Keywords Programmed death ligand 1 Bile tract neoplasm Biopsy specimen Immunohistochemistry
Note The version of record of this article, first published in Journal of Gastrointestinal Surgery, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11605-021-05197-6|
Published Date 2022-02-08
Publication Title Journal of Gastrointestinal Surgery
Volume volume26
Issue issue6
Publisher Springer Science and Business Media LLC
Start Page 1213
End Page 1223
ISSN 1091-255X
NCID AA11494553
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 35137343
DOI 10.1007/s11605-021-05197-6
Web of Science KeyUT 000752761400001
Related Url isVersionOf https://doi.org/10.1007/s11605-021-05197-6
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Author Yamamoto, Hiromasa| Soh, Junichi| Okumura, Norihito| Suzuki, Hiroyuki| Nakata, Masao| Fujiwara, Toshiya| Gemba, Kenichi| Sano, Isao| Fujinaga, Takuji| Kataoka, Masafumi| Terazaki, Yasuhiro| Fujimoto, Nobukazu| Kataoka, Kazuhiko| Kosaka, Shinji| Yamashita, Motohiro| Inokawa, Hidetoshi| Inoue, Masaaki| Nakamura, Hiroshige| Yamashita, Yoshinori| Hotta, Katsuyuki| Yoshioka, Hiroshige| Morita, Satoshi| Matsuo, Keitaro| Sakamoto, Junichi| Date, Hiroshi| Toyooka, Shinichi|
Published Date 2023-05-19
Publication Title PLoS ONE
Volume volume18
Issue issue5
Publisher Public Library of Science
Start Page e0285273
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Yamamoto et al.
File Version publisher
PubMed ID 37205678
DOI 10.1371/journal.pone.0285273
Web of Science KeyUT 001050599900034
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0285273
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Author Morinaga, Takao| Inozume, Takashi| Kawazu, Masahito| Ueda, Youki| Sax, Nicolas| Yamashita, Kazuo| Kawashima, Shusuke| Nagasaki, Joji| Ueno, Toshihide| Lin, Jason| Ohara, Yuuki| Kuwata, Takeshi| Yukami, Hiroki| Kawazoe, Akihito| Shitara, Kohei| Honobe-Tabuchi, Akiko| Ohnuma, Takehiro| Kawamura, Tatsuyoshi| Umeda, Yoshiyasu| Kawahara, Yu| Nakamura, Yasuhiro| Kiniwa, Yukiko| Morita, Ayako| Ichihara, Eiki| Kiura, Katsuyuki| Enokida, Tomohiro| Tahara, Makoto| Hasegawa, Yoshinori| Mano, Hiroyuki| Suzuki, Yutaka| Nishikawa, Hiroyoshi| Togashi, Yosuke|
Published Date 2022-07-28
Publication Title Cancer Research Communications
Volume volume2
Issue issue7
Publisher American Association for Cancer Research
Start Page 739
End Page 753
ISSN 2767-9764
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors
File Version publisher
PubMed ID 36923281
DOI 10.1158/2767-9764.CRC-22-0050
Web of Science KeyUT 001048412300001
Related Url isVersionOf https://doi.org/10.1158/2767-9764.CRC-22-0050
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Author Sun, Hongming| Morihara, Ryuta| Feng, Tian| Bian, Zhihong| Yu, Haibo| Hu, Xiao| Hu, Xinran| Bian, Yuting| Sasaki, Ryo| Fukui, Yusuke| Takemoto, Mami| Yunoki, Taijun| Nakano, Yumiko| Abe, Koji| Yamashita, Toru|
Keywords ischemic stroke human cord blood-endothelial progenitor cells mechanical thrombectomy intimal hyperplasia
Published Date 2023-08-24
Publication Title Cell Transplantation
Volume volume32
Publisher SAGE Publications
ISSN 0963-6897
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37615293
DOI 10.1177/09636897231193069
Web of Science KeyUT 001059017900001
Related Url isVersionOf https://doi.org/10.1177/09636897231193069
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Author Yamamoto, Shumpei| Kinugasa, Hideaki| Yamasaki, Yasushi| Hirai, Mami| Ako, Soichiro| Takei, Kensuke| Igawa, Shoko| Yasutomi, Eriko| Oka, Shohei| Ohmori, Masayasu| Inokuchi, Toshihiro| Harada, Keita| Hiraoka, Sakiko| Nouso, Kazuhiro| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords colorectal ESD PECS electrocoagulation syndrome immunosuppressants and steroids post-ESD fever
Published Date 2021-12-09
Publication Title DEN Open
Volume volume2
Issue issue1
Publisher Wiley
Start Page e83
ISSN 2692-4609
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
PubMed ID 35310725
DOI 10.1002/deo2.83
Web of Science KeyUT 001047024900091
Related Url isVersionOf https://doi.org/10.1002/deo2.83
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Author Hiraoka, Tomohiro| Kawamura, Mai| Takada, Keisuke| Moriwake, Tadashi|
Keywords Cystinuria Ureterolithiasis Cystine Acute appendicitis Case report
Published Date 2022-10
Publication Title International Journal of Surgery Case Reports
Volume volume99
Publisher Elsevier
Start Page 107596
ISSN 2210-2612
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 36115118
DOI 10.1016/j.ijscr.2022.107596
Web of Science KeyUT 001043865800003
Related Url isVersionOf https://doi.org/10.1016/j.ijscr.2022.107596
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Author Kanzaki, Hiromitsu| Horii, Joichiro| Takenaka, Ryuta| Nakagawa, Hiroyuki| Matsueda, Kazuhiro| Tsuzuki, Takao| Kita, Masahide| Yamasaki, Yasushi| Tanaka, Takehiro| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Tomoda, Jun| Okada, Hiroyuki|
Published Date 2022-06-10
Publication Title Endoscopy International Open
Volume volume10
Issue issue06
Publisher Georg Thieme Verlag KG
Start Page E712
End Page E718
ISSN 2364-3722
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022. The Author(s).
File Version publisher
PubMed ID 35859656
DOI 10.1055/a-1793-9439
Web of Science KeyUT 000826506700001
Related Url isVersionOf https://doi.org/10.1055/a-1793-9439
JaLCDOI 10.18926/AMO/65752
FullText URL 77_4_415.pdf
Author Jelcic, Dzenis| Puzovic, Velibor| Benzon, Benjamin| Palada, Ivan| Jerković, Jelena| Vulic, Marko|
Abstract The aim of our study was to determine whether the immunohistochemical expression of placental vitamin D receptors is altered in pregnancies complicated by preeclampsia. Vitamin D receptor expression was immunohistochemically analysed in the placentas of three groups: a control group, and early- and late-onset preeclampsia groups. Total immunohistochemical intensity staining of placentas showed that the control group had a median vitamin D receptor (VDR) expression significantly higher than the placentas of mothers with early- and late-onset preeclampsia. There was no difference among the three groups in a semiquantitative analysis of VDR staining of the stroma only. Vitamin D receptors showed lower median expression in preeclampsia-affected pregnancies, especially early-onset preeclampsia. Therefore, Vitamin D receptor expression may be an important marker for normal placentation and preeclampsia onset.
Keywords vitamin D receptor immunohistochemistry early and late-onset preeclampsia
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 415
End Page 422
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635142
Web of Science KeyUT 001163659800006
JaLCDOI 10.18926/AMO/65748
FullText URL 77_4_377.pdf
Author Morimoto, Kosaku| Takeuchi, Yasuto| Takaki, Akinobu| Wada, Nozomu| Oyama, Atsushi| Adachi, Takuya| Onishi, Hideki| Shiraha, Hidenori| Okada, Hiroyuki|
Abstract Liver fibrosis is an important phenomenon in non-alcoholic fatty liver disease (NAFLD) progression. Standard markers reflecting liver fibrosis, including the FIB-4 index, increase with age. This study aimed to identify fibrosis progression-related markers that are diagnostically beneficial even in aged individuals. Serum levels of pro- and anti-inflammatory cytokines were measured by multiple enzyme-linked immunosorbent assay. Two standard NAFLD or fibrosis progression-related markers — the FIB-4 index and APRI score — were analyzed along with cytokine levels to define the best approach to discriminate advanced fibrosis. Ninety-eight NAFLD patients were enrolled: 59 and 39 patients with fibrosis stages 1-2 and 3-4 respectively. In addition to the FIB-4 index and APRI score, the following factors showed significant differences between stages 1-2 and stages 3-4 in a multivariate analysis: platelet counts, IP-10, and RANTES. The fibrosis stage, FIB-4, APRI, PDGF-BB, and RANTES were related to the prognosis. In aged patients, IP-10, GM-CSF, and RANTES differed between stages 1-2 and stages 3-4. FIB-4 and APRI were beneficial for their correlation with fibrosis. However, to stratify either young or elderly advanced fibrosis patients, and to identify patients likely to have a bad outcome, RANTES was the best marker.
Keywords NAFLD NASH liver fibrosis chemokine FIB-4
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 377
End Page 385
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635138
Web of Science KeyUT 001163659800009
JaLCDOI 10.18926/AMO/65746
FullText URL 77_4_371.pdf
Author Iwamoto, Yosuke| Kaya, Mitsunori| Kijima, Hiroaki| Fujii, Masashi| Nagahata, Itsuki| Miyakoshi, Naohisa|
Abstract In recent publications on greater trochanteric pain syndrome (GTPS), the pathology receiving the most attention has been gluteus medius muscle tendinous injury, and surgical techniques such as gluteus medius tendon repair and their outcomes for GTPS have been reported. In our department-related facilities, arthroscopic surgeries are routinely performed for the patients with recalcitrant GTPS. A total of 51 patients were diagnosed with GTPS. Surgical treatment was carried out 22 patients (24 joints; 4 males and 18 females; mean age at surgery of 52.0 years). Arthroscopic findings confirmed bursitis in all 24 joints. In all cases, debridement of the greater trochanter bursa provided rapid relief of greater trochanter pain. The Numerical Rating Scale showed significant improvement, from the preoperative mean of 7.8 (range, 6-10) to the postoperative day 7 mean of 1.6 (range, 0-3). The modified Harris Hip Score was significantly improved from the preoperative mean of 65.5 (range, 52.5-78.3) to the final follow-up (average 2.9 months) mean of 96.0 (range, 85.2-100). Fascial damage of the gluteus medius muscle was observed in 21 joints while only 2 patients had a gluteus medius tendinous injury. Greater trochanteric bursitis and fascia or muscle-fiber injury of the gluteus medius muscle are the most common pathologies in patients with lateral hip pain.
Keywords greater trochanteric pain syndrome endoscopic findings bursitis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 371
End Page 375
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635137
Web of Science KeyUT 001163659800005
JaLCDOI 10.18926/AMO/65745
FullText URL 77_4_365.pdf
Author Moldovan, Elena| Bănescu, Claudia| Cucerea, Manuela| Moldovan, Valeriu| Gozar, Liliana| Pușcașiu, Lucian|
Abstract Congenital heart disease is the most common malformative pathology in newborns, with a worldwide incidence at 0.4-5%. We investigated the possible relationship between variations in nucleotide sequences and specific cardiac malformations in the GATA-binding factor 4 (GATA4) exon 1 region by using Sanger sequencing. Forty-four newborns from a third-level neonatal intensive care unit who were diagnosed with nonsyndromic, ductal-dependent congenital heart disease (i.e., transposition of the great arteries or ductal-dependent coarctation of the aorta) were enrolled. Their DNA was extracted using commercial methods and tested using the multiplex ligation-dependent probe amplification (MLPA) technique. The Sanger sequencing for GATA4 exon 1 in the newborns’ DNA identified rs61277615, rs73203482, and rs35813172 variants not reported in the ClinVar archive of human variations in newborns previously diagnosed with transposition of the great arteries (n=5) and coarctation of the aorta (n=1). The identification of these novel variants in newborns with transposition of the great arteries or ductal-dependent coarctation of the aorta may be the first step in determining the variants’ contribution to the occurrence of congenital heart disease. However, these results may be inconclusive, since the observed variants within GATA4 gene were not previously reported.
Keywords transposition of the great arteries ductal-dependent coarctation of the aorta GATA4 MLPA Sanger sequencing
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 365
End Page 370
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635136
Web of Science KeyUT 001163659800008
FullText URL fulltext.pdf
Author Sukegawa, Shintaro| Ono, Sawako| Tanaka, Futa| Inoue, Yuta| Hara, Takeshi| Yoshii, Kazumasa| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Katsumitsu, Shimada| Nakai, Fumi| Nakai, Yasuhiro| Miyazaki, Ryo| Murakami, Satoshi| Nagatsuka, Hitoshi| Miyake, Minoru|
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-38343-y|
Published Date 2023-07-19
Publication Title Scientific Reports
Volume volume13
Issue issue1
Publisher Nature Portfolio
Start Page 11676
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37468501
DOI 10.1038/s41598-023-38343-y
Web of Science KeyUT 001033545700013
Related Url isVersionOf https://doi.org/10.1038/s41598-023-38343-y
FullText URL fulltext.pdf
Author Chen, Mengxi| Tanaka, Takehiro| Igawa, Takuro| Han, Yanyan| Peng, Fangli| Jin, Zaishun| Yoshino, Tadashi|
Keywords PDX1 PTF1A SALL4 Ectopic pancreas Gastro-duodenum Jejunum
Published Date 2023-07
Publication Title Heliyon
Volume volume9
Issue issue7
Publisher Cell Press
Start Page e18241
ISSN 2405-8440
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37519669
DOI 10.1016/j.heliyon.2023.e18241
Web of Science KeyUT 001043928200001
Related Url isVersionOf https://doi.org/10.1016/j.heliyon.2023.e18241
JaLCDOI 10.18926/AMO/65740
FullText URL 77_4_347.pdf
Author Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki|
Abstract The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry.
Keywords flow cytometry stem cell transplantation transplantation-associated microangiopathy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 347
End Page 357
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635134
Web of Science KeyUT 001163659800002