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Author Tanaka, Hiroyoshi Y.| Nakazawa, Takuya| Enomoto, Atsushi| Masamune, Atsushi| Kano, Mitsunobu R.|
Keywords pancreatic cancer tumor microenvironment nanomedicine fibrosis extracellular matrix fibroblast
Published Date 2023-01-24
Publication Title Cancers
Volume volume15
Issue issue3
Publisher MDPI
Start Page 724
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36765684
DOI 10.3390/cancers15030724
Web of Science KeyUT 000929314700001
Related Url isVersionOf https://doi.org/10.3390/cancers15030724
FullText URL fulltext.pdf
Author Kawai, Hotaka| Oo, May Wathone| Takabatake, Kiyofumi| Tosa, Ikue| Soe, Yamin| Eain, Htoo Shwe| Sanou, Sho| Fushimi, Shigeko| Sukegawa, Shintaro| Nakano, Keisuke| Takeshi, Takarada| Nagatsuka, Hitoshi|
Keywords BONE FORMATION BONE MARROW MESENCHYMAL STEM CELLS BONE MARROW TRANSPLANTATION MODEL OSTEOBLASTS SYSTEM BIOLOGY-BONE INTERACTOR
Published Date 2023-01-23
Publication Title JBMR PLUS
Publisher WILEY
ISSN 2473-4039
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
DOI 10.1002/jbm4.10722
Web of Science KeyUT 000935649100001
Related Url isVersionOf https://doi.org/10.1002/jbm4.10722
FullText URL fulltext.pdf
Author Fujita, Hirofumi| Ando, Aoi| Mizusawa, Yohei| Ono, Mitsuaki| Hattori, Takako| Habuta, Munenori| Oohashi, Toshitaka| Kubota, Satoshi| Ohuchi, Hideyo|
Published Date 2022-11-17
Publication Title Plos One
Volume volume17
Issue issue11
Publisher Public Library Science
Start Page e0277307
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Fujita et al.
File Version publisher
PubMed ID 36395281
DOI 10.1371/journal.pone.0277307
Web of Science KeyUT 000926013600060
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0277307
Title Alternative Reports of the 67th Autumn Annual Meeting of the Japanese Society of Pathology, the 12th Asia-Pacific IAP Meeting and the 61th Annual Meeting of the Japanese Society for Lymphoreticular Tissue Research
FullText URL 134_54.pdf
Author Yoshino, Tadashi|
Publication Title Journal of Okayama Medical Association
Published Date 2022-04-01
Volume volume134
Issue issue1
Start Page 54
End Page 55
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.54
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.54
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Okada, Horoyuki|
Keywords carcinogenesis lymphocytes helicobacter pylori gastric adenocarcinoma flow cytometry
Published Date 2022-11-20
Publication Title Cureus Journal Of Medical Science
Volume volume14
Issue issue11
Publisher Cureus Inc.
Start Page e31713
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Iwamuro et al.
File Version publisher
PubMed ID 36569708
DOI 10.7759/cureus.31713
Web of Science KeyUT 000918257500029
Related Url isVersionOf https://doi.org/10.7759/cureus.31713
JaLCDOI 10.18926/AMO/64365
FullText URL 77_1_75.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Abstract Herein, we report two patients with autoimmune gastritis who had undergone multiple esophagogastroduodenoscopy procedures for 17 and 9 years, respectively, before their diagnosis. Instead, they had been diagnosed with and treated for Helicobacter pylori-associated gastritis. The correct diagnosis was made when scatterings of tiny whitish protrusions in the gastric mucosa were detected on esophagogastroduodenoscopy. Our findings suggest that scattered tiny whitish bumps may be a clue to the diagnosis of autoimmune gastritis.
Keywords autoimmune gastritis esophagogastroduodenoscopy scattered lesions small white protrusions mucosal lesions
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 75
End Page 80
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849149
Web of Science KeyUT 000952973200001
JaLCDOI 10.18926/AMO/64363
FullText URL 77_1_65.pdf
Author Sato, Ken| Takigawa, Nagio| Kubo, Toshio| Katayama, Hideki| Kishino, Daizo| Okada, Toshiaki| Hisamoto, Akiko| Mimoto, Junko| Ochi, Nobuaki| Yoshino, Tadashi| Ueoka, Hiroshi| Tanimoto, Mitsune| Maeda, Yoshionobu| Kiura, Katsuyuki|
Abstract We investigated the effects of celecoxib combined with (−)-epigallocatechin-3-gallate (EGCG) or polyphenon E in a cisplatin-induced lung tumorigenesis model. Four-week-old female A/J mice were divided into seven groups: (i) Control, (ii) 150 mg/kg celecoxib (150Cel), (iii) 1,500 mg/kg celecoxib (1500Cel), (iv) EGCG+150 mg/kg celecoxib (EGCG+150Cel), (v) EGCG+1,500 mg/kg celecoxib (EGCG+1500Cel), (vi) polyphenon E+150 mg/kg celecoxib (PolyE+150Cel), and (vii) polyphenon E+1,500 mg/kg celecoxib (PolyE+1500Cel). All mice were administered cisplatin (1.62 mg/kg of body weight, i.p.) 1×/week for 10 weeks and sacrificed at week 30; the numbers of tumors on the lung surface were then determined. The tumor incidence and multiplicity (no. of tumors/mouse, mean±SD) were respectively 95% and 2.15±1.50 in Control, 95% and 2.10±1.29 in 150Cel, 86% and 1.67±1.20 in 1500Cel, 71% and 1.38±1.24 in EGCG+150Cel, 67% and 1.29±1.38 in EGCG+1500Cel, 80% and 1.95±1.36 in PolyE+150Cel, and 65% and 1.05±0.10 in PolyE+1500Cel. The combination of high-dose celecoxib with EGCG or polyphenon E significantly reduced multiplicity in cisplatin-induced lung tumors.
Keywords celecoxib cisplatin EGCG lung tumor polyphenon E
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 65
End Page 70
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849147
Web of Science KeyUT 000952992100004
JaLCDOI 10.18926/AMO/64362
FullText URL 77_1_57.pdf
Author Katsumata, Ryo| Manabe, Noriaki| Monobe, Yasumasa| Ayaki, Maki| Suehiro, Mitsuhiko| Fujita, Minoru| Kamada, Tomoari| Kawamoto, Hirofumi| Haruma, Ken|
Abstract Melanosis coli (MC) is an acquired colorectal disorder visualized as colonic mucosa pigmentation. Disease severity is confirmed based on MC depth, shape, and coloration, although the clinical course is not fully understood. This study sought to clarify characteristics of MC development and disappearance and to investigate its clinical course and severity. Contributors to MC grade progression were explored. This study reviewed MC cases discovered via colonoscopy at a single institution over a 10-year period. Of all 216 MC cases, 17 developing and 10 disappearing cases were detected. Anthranoid laxative use was a key factor: 29.4% of the developing cases had used such agents before the initial MC diagnosis, whereas 40% of disappearing cases had discontinued anthranoids prior to detection of MC disappearance. Among 70 grade I cases, progression to grade II occurred in 16 cases during a mean follow-up of 3.67±2.1 years (rate of progression=22.8%). Males more commonly showed progressive than stable grade I cases, and the probability of progression was higher for male than for female cases. An association between anthranoid administration and MC presence was presumed, and grade I MC was found to progress in severity over 5 years.
Keywords melanosis sex characteristics laxatives colorectal neoplasms colonoscopy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 57
End Page 64
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849146
Web of Science KeyUT 000952992100003
JaLCDOI 10.18926/AMO/64358
FullText URL 77_1_29.pdf
Author Yamamoto, Shusei| Sato, Ikumi| Fujii, Moe| Kakimoto, Mai| Honma, Koki| Akiyama, Natsumi| Sakai, Miku| Fukuhama, Natsuki| Kumazaki, Shota| Hirohata, Satoshi| Kitamori, Kazuya| Yamori, Yukio| Watanabe, Shogo|
Abstract The SHRSP5/Dmcr is a useful animal model for the development of nonalcoholic steatohepatitis (NASH) pathology when fed a high-fat, high-cholesterol diet, and further drug interventions can lead to concomitant cardiovascular disease. While SHRSP5/Dmcr rats have been used for basic research related to NASH, details of their bile acid metabolism in this condition are unknown. In this study, we aimed to clarify the changes in the serum bile acid (BA) fractions associated with NASH and found that glycine-conjugated and unconjugated bile acid increased with worsening NASH and cardiovascular disease while taurine-conjugated BA relatively decreased.
Keywords SHRSP5/Dmc nonalcoholic steatohepatitis cardiovascular disease glycine-conjugated bile acids unconjugated bile acids
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 29
End Page 36
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849143
Web of Science KeyUT 000953019200001
FullText URL fulltext.pdf
Author Ayada, Yoshiyuki| Igawa, Takuro| Naoi, Yusuke| Horikawa, Kyosuke| Tabata, Tetsuya| Tanaka, Takehiro| Yoshino, Tadashi|
Keywords MALT lymphoma chronic gastritis reactive lymphoid hyperplasia IRTA1 MNDA
Published Date 2022
Publication Title Journal of clinical and experimental hematopathology
Volume volume62
Issue issue4
Publisher The Japanese Society for Lymphoreticular Tissue Research
Start Page 195
End Page 201
ISSN 1346-4280
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 36436933
DOI 10.3960/jslrt.22021
Web of Science KeyUT 000911719800002
Related Url isVersionOf https://doi.org/10.3960/jslrt.22021
FullText URL fulltext.pdf
Author Wang, Yuze| Ohara, Toshiaki| Chen, Yuehua| Hamada, Yusuke| Li, Chunning| Fujisawa, Masayoshi| Yoshimura, Teizo| Matsukawa, Akihiro|
Keywords triple-negative breast cancer iron metabolism iron chelator phosphoinositide-3-kinase-protein kinase heterogeneity metastasis
Published Date 2023-01-12
Publication Title Cancers
Volume volume15
Issue issue2
Publisher MDPI
Start Page 468
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36672419
DOI 10.3390/cancers15020468
Web of Science KeyUT 000914513700001
Related Url isVersionOf https://doi.org/10.3390/cancers15020468
FullText URL fulltext.pdf
Author Murakami, Hiroyuki| Matsuoka, Ken-Ichi| Asano, Takeru| Moriyama, Takashi| Matsumura, Akifumi| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Nishimori, Hisakazu| Fujii, Keiko| Fujii, Nobuharu| Toji, Tomohiro| Yoshino, Tadashi| Maeda, Yoshinobu|
Keywords Refractory acute myeloid leukemia Transplant B-cell lymphoma-2 Azacitidine Venetoclax
Published Date 2022-11-08
Publication Title Case Reports In Oncology
Volume volume15
Issue issue3
Publisher Karger
Start Page 974
End Page 979
ISSN 1662-6575
NCID AA12780955
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Author(s).
File Version publisher
PubMed ID 36636684
DOI 10.1159/000526697
Web of Science KeyUT 000905485600025
Related Url isVersionOf https://doi.org/10.1159/000526697
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Kono, Yoshiyasu| Kawano, Seiji| Okada, Horoyuki|
Keywords nivolumab ipilimumab immune -related adverse events immune checkpoint inhibitor esophagogastroduodenoscopy
Published Date 2022-12-19
Publication Title CUREUS JOURNAL OF MEDICAL SCIENCE
Volume volume14
Issue issue12
Publisher Cureus
Start Page e32710
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Iwamuro et al.
File Version publisher
PubMed ID 36686096
DOI 10.7759/cureus.32710
Web of Science KeyUT 000905471200003
Related Url isVersionOf https://doi.org/10.7759/cureus.32710
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Matsumura, Akifumi| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Published Date 2022-12-31
Publication Title Case Reports In Gastrointestinal Medicine
Volume volume2022
Publisher Hindawi Ltd
Start Page 4637707
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Masaya Iwamuro et al.
File Version publisher
PubMed ID 36624891
DOI 10.1155/2022/4637707
Web of Science KeyUT 000910999400001
Related Url isVersionOf https://doi.org/10.1155/2022/4637707
FullText URL fulltext.pdf
Author Hayashi, Keigo| Sada, Ken-Ei| Asano, Yosuke| Katayama, Yu| Ohashi, Keiji| Morishita, Michiko| Miyawaki, Yoshia| Watanabe, Haruki| Katsuyama, Takayuki| Narazaki, Mariko| Matsumoto, Yoshinori| Yajima, Nobuyuki| Yoshimi, Ryusuke| Shimojima, Yasuhiro| Ohno, Shigeru| Kajiyama, Hiroshi| Ichinose, Kunihiro| Sato, Shuzo| Fujiwara, Michio| Wada, Jun|
Published Date 2022-06-29
Publication Title Plos One
Volume volume17
Issue issue6
Publisher Public Library Science
Start Page e0270569
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Hayashi et al.
File Version publisher
PubMed ID 35767524
DOI 10.1371/journal.pone.0270569
Web of Science KeyUT 000892027900189
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0270569
FullText URL fulltext.pdf
Author Eguchi, Takanori| Csizmadia, Eva| Kawai, Hotaka| Sheta, Mona| Yoshida, Kunihiro| Prince, Thomas L.| Wegiel, Barbara| Calderwood, Stuart K.|
Keywords epithelial-to-mesenchymal transition (EMT) hybrid E/M partial EMT SCAND1 MZF1 SCAN zinc finger transcription factors gene expression cancer prognosis collective migration metastasis
Published Date 2022-12-10
Publication Title Cells
Volume volume11
Issue issue24
Publisher MDPI
Start Page 3993
ISSN 2073-4409
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36552758
DOI 10.3390/cells11243993
Web of Science KeyUT 000900505200001
Related Url isVersionOf https://doi.org/10.3390/cells11243993
FullText URL fulltext.pdf
Author Yamasuji-Maeda, Yoshiko| Nishimori, Hisakazu| Seike, Keisuke| Yamamoto, Akira| Fujiwara, Hideaki| Kuroi, Taiga| Saeki, Kyosuke| Fujinaga, Haruko| Okamoto, Sachiyo| Matsuoka, Ken-Ichi| Fujii, Nobuharu| Tanaka, Takehiro| Fujii, Masahiro| Mominoki, Katsumi| Kanekura, Takuro| Maeda, Yoshinobu|
Published Date 2022-09-09
Publication Title PLOS One
Volume volume17
Issue issue9
Publisher Public Library Science
Start Page e0273749
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Yamasuji-Maeda et al.
File Version publisher
PubMed ID 36084023
DOI 10.1371/journal.pone.0273749
Web of Science KeyUT 000892051000058
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0273749
FullText URL fulltext.pdf
Author Kakiuchi, Yoshihiko| Kikuchi, Satoru| Kuroda, Shinji| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords Remnant gastric cancer Prognostic factor Tumor-infiltrating lymphocytes CD8(+) T cell Tumor immunity
Published Date 2022-11-30
Publication Title World Journal Of Surgical Oncology
Volume volume20
Issue issue1
Publisher BMC
Start Page 374
ISSN 1477-7819
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36451224
DOI 10.1186/s12957-022-02853-2
Web of Science KeyUT 000892980100002
Related Url isVersionOf https://doi.org/10.1186/s12957-022-02853-2
FullText URL fulltext20221215-1.pdf figures20221215-1.pdf Supple_Figures20221215-1.pdf Supple_Table20221215-1.pdf
Author Kajiwara, Yoshinori| Tazawa, Hiroshi| Yamada, Motohiko| Kanaya, Nobuhiko| Fushimi, Takuro| Kikuchi, Satoru| Kuroda, Shinji| Ohara, Toshiaki| Noma, Kazuhiro| Yoshida, Ryuichi| Umeda, Yuzo| Urata, Yasuo| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Keywords Pancreatic cancer Chemoresistance MDSC GM-CSF Oncolytic virus
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00262-022-03334-x| This full-text of the article will be available in Nov. 2023.|
Published Date 2022-11-27
Publication Title Cancer Immunology, Immunotherapy
Volume volume72
Issue issue5
Publisher Springer Science and Business Media LLC
Start Page 1285
End Page 1300
ISSN 0340-7004
NCID AA00598499
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022
File Version author
PubMed ID 36436021
DOI 10.1007/s00262-022-03334-x
Web of Science KeyUT 000889040300003
Related Url isVersionOf https://doi.org/10.1007/s00262-022-03334-x
FullText URL fulltext.pdf
Author Sato, Hiroaki| Noma, Kazuhiro| Ohara, Toshiaki| Kawasaki, Kento| Akai, Masaaki| Kobayashi, Teruki| Nishiwaki, Noriyuki| Narusaka, Toru| Komoto, Satoshi| Kashima, Hajime| Katsura, Yuki| Kato, Takuya| Kikuchi, Satoru| Tazawa, Hiroshi| Kagawa, Shunsuke| Shirakawa, Yasuhiro| Kobayashi, Hisataka| Fujiwara, Toshiyoshi|
Published Date 2022-11-23
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher Nature Portfolio
Start Page 20152
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 36418422
DOI 10.1038/s41598-022-24313-3
Web of Science KeyUT 000887936300054
Related Url isVersionOf https://doi.org/10.1038/s41598-022-24313-3