Conditions

close

result 244 件

FullText URL fulltext.pdf
Author Tsumura, Munechika| Makihara, Seiichiro| Nishikori, Asami| Gion, Yuka| Morito, Toshiaki| Miyamoto, Shotaro| Naito, Tomoyuki| Uraguchi, Kensuke| Oka, Aiko| Tachibana, Tomoyasu| Orita, Yorihisa| Kariya, Shin| Okano, Mitsuhiro| Ando, Mizuo| Sato, Yasuharu|
Keywords HPV infection sinonasal inverted papilloma diabetes mellitus young adult tumor stage
Published Date 2022-02-10
Publication Title Diagnostics
Volume volume12
Issue issue2
Publisher MDPI
Start Page 454
ISSN 2075-4418
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 35204545
DOI 10.3390/diagnostics12020454
Web of Science KeyUT 000767759900001
Related Url isVersionOf https://doi.org/10.3390/diagnostics12020454
JaLCDOI 10.18926/CTED/63316
Title Alternative The Specific Practice of School Based Curriculum Development - Organizational Practice of Japanese language learning through the Interpretation of the School Educational Aims -
FullText URL cted_012_317.pdf
Author Inamoto, Takashi| Miyamoto, Koji|
Abstract 本研究の目的は,学校カリキュラムの開発において,「目指す子ども像」の共有と,その姿の実現に向けた取り組みの具体的な展開,実践の詳細を検討することにある。具体的には,カリキュラム開発に携わるリーダーシップと意思決定のあり方,そしてそれが機能した(機能しつつある)開発の過程についての事例として,岡山大学教育学部附属小学校国語部の取り組みを検討した。検討を通じて明らかになったことは,「目指す子ども像」をもとに授業自体を解釈し直し,授業の意味を探ることを通じて,授業者自身にも「目指す子ども像」を具現化した授業がイメージできるようになり,学校全体を通じた組織的な取り組みとなる可能性があるということである。さらに,こうした取り組みを行う中で,実践的リーダーは,解釈のモデルを示したり,やりとりをする中で別の解釈を引き出したりすることや,解釈自体を修正したりすることが重要となることが明らかになった。
Keywords カリキュラム開発(Curriculum Development) 「目指す子ども像」の共有と解釈(Sharing and Interpreting the Appearance of Children Trying to Raise) リーダーシップ(Leadership) 組織開発(Organizational Development)
Publication Title Bulletin of Center for Teacher Education and Development, Okayama University
Published Date 2022-03-30
Volume volume12
Start Page 317
End Page 327
ISSN 2186-1323
language Japanese
Copyright Holders Copyright © 2022 岡山大学教師教育開発センター
File Version publisher
FullText URL K0006448_abstract_review.pdf K0006448_fulltext.pdf
Author Imamura, Mariko|
Published Date 2021-09-24
Content Type Thesis or Dissertation
Grant Number 甲第6448号
Granted Date 2021-09-24
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders Copyright © 2021 Mise, Imamura, Yamaguchi, Watanabe, Higuchi, Katayama, Miyamoto, Uchida, Nakatsuka, Eguchi, Hida, Nakato, Tone, Teshigawara, Matsuoka, Kamei, Murakami, Shimizu, Miyashita, Ando, Nunoue, Yoshida, Yamada, Shikata and Wada.
FullText URL fulltext.pdf
Author Yamazaki, Tatsuhiro| Tomoda, Takeshi| Kato, Hironari| Miyamoto, Kazuya| Matsumi, Akihiro| Ueta, Eijiro| Fujii, Yuki| Saragai, Yosuke| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki|
Keywords surveillance prognosis factor intraductal papillary mucinous neoplasm pancreatic cancer
Published Date 2021-10-15
Publication Title Internal Medicine
Volume volume60
Issue issue20
Publisher The Japanese Society of Internal Medicine
Start Page 3205
End Page 3211
ISSN 0918-2918
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 33967138
DOI 10.2169/internalmedicine.7168-21
Web of Science KeyUT 000709798800002
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.7168-21
JaLCDOI 10.18926/AMO/62814
FullText URL 75_6_735.pdf
Author Nagai, Yasuo| Takagi, Kosei| Kuise, Takashi| Umeda, Yuzo| Yoshida, Ryuichi| Yoshida, Kazuhiro| Yasui, Kazuya| Yagi, Takahito| Fujiwara, Toshiyoshi|
Abstract Surgical intervention for hepatolithiasis following hepaticojejunostomy (HJ) has rarely been reported. Herein, we present a case of post-HJ multiple hepatolithiasis treated with left hemihepatectomy with double HJ reconstruction. A 72-year-old woman who had undergone HJ for iatrogenic bile duct injury developed repeated cholangitis due to complicated hepatolithiasis accompanied by an atrophied left hepatic lobe and HJ stricture. Since endoscopic intervention was unsuccessful, the patient underwent left hemihepatectomy with HJ re-anastomoses of the common hepatic duct and left hepatic duct (double HJ technique). The double HJ technique with hepatectomy can be a useful option for treating complicated hepatolithiasis following HJ.
Keywords hepatolithiasis hepaticojejunostomy hepatectomy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-12
Volume volume75
Issue issue6
Publisher Okayama University Medical School
Start Page 735
End Page 739
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34955542
Web of Science KeyUT 000735297900009
NAID 120007180278
JaLCDOI 10.18926/AMO/62809
FullText URL 75_6_699.pdf
Author Kawano, Tetsuya| Miyakoshi, Naohisa| Tsuchie, Hiroyuki| Kashiwagura, Takeshi| Kobayashi, Moto| Aonuma, Hiroshi| Sugimura, Yusuke| Shimada, Yoichi|
Abstract Glucocorticoid-induced osteoporosis (GIOP) is one of the side effects associated with glucocorticoid (GC) therapy. In 2014, the Japanese Society for Bone and Mineral Research (JSBMR) provided new guidelines for the management and treatment of GIOP. The aim of the present study was to clarify the prevalence of patients with rheumatoid arthritis (RA) requiring treatment according to the new guidelines and to identify risk factors associated with lack of treatment in these patients. Patients in the 2018 Akita Orthopedic group on Rheumatoid Arthritis (AORA) database were enrolled. Of 2,234 patients with RA in the database, 683 (30.6%) met the 2014 JSBMR guideline treatment criteria, and 480 (70.3%) had been treated. The untreated group included a larger number of males, younger patients, and patients treated in clinics rather than hospital (p<0.001, p=0.015, and p<0.001, respectively). Multivariate analyses found that male sex, younger age, and clinic-based RA care were significant risk factors associated with lack of treatment (p<0.001, p=0.013, and p<0.001, respectively). Thus, male sex, younger age, and clinic-based care were identified as risk factors
Keywords glucocorticoid glucocorticoid-induced osteoporosis rheumatoid arthritis osteoporosis osteopenia
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-12
Volume volume75
Issue issue6
Publisher Okayama University Medical School
Start Page 699
End Page 704
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34955537
Web of Science KeyUT 000735297900005
NAID 120007180283
FullText URL fulltext20211015-1.pdf
Author Morita, Hiroshi| Miyamoto, Masakazu|
Keywords Brugada syndrome Early repolarization syndrome J wave syndrome
Note © 2021 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.tcm.2021.08.003] .|
Published Date 2021-08-10
Publication Title Trends in Cardiovascular Medicine
Publisher Elsevier Inc.
Start Page 1
ISSN 10501738
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Elsevier Inc. All rights reserved.
File Version author
PubMed ID 34389408
DOI 10.1016/j.tcm.2021.08.003
Related Url isVersionOf https://doi.org/10.1016/j.tcm.2021.08.003
JaLCDOI 10.18926/AMO/62402
FullText URL 75_4_495.pdf
Author Sugiyama, Shuntaro| Iida, Takatoshi| Morimoto, Yoshinari| Yamazaki, Yuki| Mikuzuki, Lou| Hayashi, Megumi|
Abstract Tablet size and head posture have been reported to affect swallowing of medications, but no previous studies have evaluated their effects in detail. Our aim was to investigate for the first time the effect of tablet size and head posture on drug swallowing by endoscopic evaluation in healthy subjects. Round tablets (7 , 10 , 12, and 14 mm in diameter) were swallowed by 15 healthy adults with an endoscope inserted in the neutral, head flex-ion, and head extension positions. Evaluation of swallowing difficulty using a numeric rating scale (NRS), presence or absence of pharyngeal residue and its location, and tablet oral transit time (TOTT) were recorded. In the neutral position, the NRS score was higher with the 14 mm tablets than with the 7 mm tablets. The TOTT with the 7 mm tablets was significantly shorter in the head extension than in the neutral position. Swallowing difficulty increased when the tablet diameter was more than 7 mm. Residues were found in the epi-glottis, pyriform sinus, and tongue base. These findings suggest that head extension shortens the TOTT and assists oral-pharyngeal transport.
Keywords tablet size head posture swallowing endoscopy pharyngeal residue
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 495
End Page 503
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511617
Web of Science KeyUT 000709282300003
NAID 120007146045
JaLCDOI 10.18926/AMO/62399
FullText URL 75_4_471.pdf
Author Iwamuro, Masaya| Toyokawa, Tatsuya| Matsueda, Kazuhiro| Hori, Shinichiro| Yoshioka, Masao| Moritou, Yuki| Tanaka, Takehiro| Mizuno, Motowo| Okada, Hiroyuki|
Abstract The characteristics of gastric polyps in patients with Peutz-Jeghers (PJ) syndrome (PJS) have not been fully investigated. The objective of this study was to reveal the endoscopic and pathologic findings of gastric polyps in patients with PJS. We reviewed 11 patients with PJS treated at 6 institutions, and summarized the endo-scopic and pathologic features of their gastric polyps. The polyps were mainly classified into 2 types: (i) soli-tary or sporadic polyps > 5 mm, reddish in color with a sessile or semi-pedunculated morphology (n = 9); and (ii) multiple sessile polyps ≤ 5 mm with the same color tone as the peripheral mucosa (n = 9). Patients who underwent endoscopic mucosal resection for polyps > 5 mm were diagnosed with PJ polyps (n = 2), whereas those who underwent biopsy were diagnosed with hyperplastic polyps. Polyps ≤ 5 mm were pathologically diagnosed as fundic gland polyps or hyperplastic polyps. This study revealed that patients with PJS present with 2 types of polyps in the stomach. Endoscopic mucosal resection of polyps > 5 mm seems necessary for the pathologic diagnosis of PJ polyps.
Keywords Peutz-Jeghers syndrome esophagogastroduodenoscopy gastric polyps
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 471
End Page 477
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511614
Web of Science KeyUT 000701717000001
NAID 120007146042
JaLCDOI 10.18926/AMO/62398
FullText URL 75_4_461.pdf
Author Murakami, Hiroyuki| Yoshioka, Takanori| Moriyama, Takashi| Ishikawa, Tatsunori| Makita, Masanori| Sunami, Kazutaka|
Abstract Bendamustine plus rituximab (B-R) is an effective therapy for relapsed or refractory (r/r) low-grade B-cell lymphoma (LGBCL) and mantle cell lymphoma (MCL); however, clinical data from Japanese patients treated with B-R therapy are limited. We retrospectively evaluated the efficacy and safety of B-R therapy in 42 patients who received B-R therapy at our hospital for r/r LGBCL and MCL. All patients received intravenous (IV) ritux-imab 375 mg/m2 on day 1 and IV bendamustine 90 mg/m2 on days 2 and 3 every 28 days for up to 6 cycles. The common histologic subtypes were follicular lymphoma (n = 29, 70%), marginal zone lymphoma (n = 6, 14%), and MCL (n = 5, 12%). The overall response rate was 93%, with 62% complete response and complete response unconfirmed. The median progression-free survival (PFS) was 38 months (95% confidence interval [CI], 24.6 to not reached [NR]), and the median overall survival (OS) was 80 months (95% CI, 60.7 to NR). Patients receiving a cumulative dose of bendamustine ≥ 720 mg/m2 showed a significantly longer PFS and OS. Grade 3/4 adverse events (≥ 10%) included neutropenia (55%), lymphopenia (69%), and nausea (24%). B-R therapy was effective and well tolerated, and the cumulative dose of bendamustine was associated with a favorable outcome.
Keywords bendamustine low grade B-cell lymphoma mantle cell lymphoma
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 461
End Page 469
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511613
Web of Science KeyUT 000697944600008
NAID 120007146041
JaLCDOI 10.18926/AMO/62378
FullText URL 75_4_403.pdf
Author Matoba, Ryo| Morizane, Yuki|
Abstract Epiretinal membrane (ERM) is a common retinal disease characterized by cellular proliferation and metaplasia that lead to the formation of a pathological fibrocellular membrane immediately superjacent to the inner retinal surface. The vast majority of ERMs are considered idiopathic. However, ERM formation can result from various primary intraocular diseases, including retinal breaks and detachment, retinal vascular diseases, and vitreoretinal inflammatory conditions. Although ERMs are generally asymptomatic or cause mild metamorphopsia and/or a modest decrease in visual acuity, some can cause severe macular distortion and macular edema, resulting in significantly impaired function. Surgical removal of ERM is the only treatment, and improvements in vitrectomy systems have enabled less invasive treatment. However, there are currently no standardized criteria for ERM surgery, and the indications for surgery are determined from the patient’s subjective symptoms. Another problem with ERM surgery is that not all patients show satisfactory postoperative recovery of visual function. Thus, further research is needed to determine the criteria for ERM surgery and methods to improve the postoperative prognosis.
Keywords epiretinal membrane vitrectomy optical coherence tomography internal limiting membrane lamellar macular hole
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 403
End Page 413
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511606
Web of Science KeyUT 000697944600001
NAID 120007146059
FullText URL fulltext.pdf
Author Obata, Taisuke| Tsutsumi, Koichiro| Kato, Hironari| Ueki, Toru| Miyamoto, Kazuya| Yamazaki, Tatsuhiro| Matsumi, Akihiro| Fujii, Yuki| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Yasugi, Kengo| Ogawa, Tsuneyoshi| Takenaka, Ryuta| Okada, Hiroyuki|
Keywords bile duct stone endoscopic retrograde cholangiography Roux-en-Y anastomosis short-type balloon enteroscopy complete stone removal gastrectomy
Published Date 2021-07-27
Publication Title Journal of Clinical Medicine
Volume volume10
Issue issue15
Publisher MDPI
Start Page 3314
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34362098
DOI 10.3390/jcm10153314
Web of Science KeyUT 000682079900001
Related Url isVersionOf https://doi.org/10.3390/jcm10153314
JaLCDOI 10.18926/AMO/62220
FullText URL 75_3_289.pdf
Author Miyamoto, Masakazu| Osawa, Kazuhiro| Miyoshi, Toru| Mori, Atsushi| Yoshikawa, Masaki| Oka, Takefumi| Ichikawa, Keishi| Nakamura, Kazufumi| Ito, Hiroshi|
Abstract Early treatment with an oral β-blocker is recommended in patients with a ST-segment–elevation myocardial infarction (STEMI). In this multicenter study, we evaluated the effects of a continuous administration of landiolol, an ultrashort-acting β-blocker, before primary percutaneous coronary intervention (PCI) on myocardial salvage and its safety in STEMI patients. A total of 47 Japanese patients with anterior or lateral STEMI undergoing a primary PCI within 12 h of symptom onset were randomized to receive intravenous landiolol (started at 3 μg/min/kg dose and continued to a total of 50 mg; n=23) or not (control; n=24). Patients with Killip class III or more were excluded. The primary outcome was the myocardial salvage index on cardiac magnetic resonance imaging (MRI) performed 5-7 days after the PCI. Cardiac MRI was performed in 35 patients (74%). The myocardial salvage index in the landiolol group was significantly greater than that in the control group (44.4±14.6% vs. 31.7±18.9%, respectively; p=0.04). There were no significant differences in adverse events at 24 h between the landiolol and control groups. A continuous administration of landiolol before a primary PCI may increase the degree of myocardial salvage without additional hemodynamic adverse effects within the first 24 h after STEMI.
Keywords myocardial infarction landiolol magnetic resonance imaging STEMI PCI
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-06
Volume volume75
Issue issue3
Publisher Okayama University Medical School
Start Page 289
End Page 297
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34176932
Web of Science KeyUT 000667147700004
NAID 120007089835
FullText URL fulltext.pdf
Author Mise, Koki| Imamura, Mariko| Yamaguchi, Satoshi| Watanabe, Mayu| Higuchi, Chigusa| Katayama, Akihiro| Miyamoto, Satoshi| Uchida, Haruhito A.| Nakatsuka, Atsuko| Eguchi, Jun| Hida, Kazuyuki| Nakato, Tatsuaki| Tone, Atsuhito| Teshigawara, Sanae| Matsuoka, Takashi| Kamei, Shinji| Murakami, Kazutoshi| Shimizu, Ikki| Miyashita, Katsuhiro| Ando, Shinichiro| Nunoue, Tomokazu| Yoshida, Michihiro| Yamada, Masao| Shikata, Kenichi| Wada, Jun|
Keywords cardiovascular event diabetes lectins N-glycans urinary biomarkers
Published Date 2021-05-24
Publication Title Frontiers In Cardiovascular Medicine
Volume volume8
Publisher Frontiers Media SA
Start Page 668059
ISSN 2297-055X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34109226
DOI 10.3389/fcvm.2021.668059
NAID 120007053373
Web of Science KeyUT 000658156400001
Related Url isVersionOf https://doi.org/10.3389/fcvm.2021.668059
FullText URL fulltext.pdf
Author Miyamoto, Masakazu| Nishii, Nobuhiro| Morita, Hiroshi| Ito, Hiroshi|
Keywords Idiopathic left ventricular tachycardia Double outlet right ventricle Fontan operation Purkinje potential Case report
Published Date 2020-09-07
Publication Title European Heart Journal-Case Reports
Volume volume4
Issue issue5
Publisher Oxford Univ Press
ISSN 2514-2119
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2020.
File Version publisher
PubMed ID 33204969
DOI 10.1093/ehjcr/ytaa264
NAID 120007042390
Web of Science KeyUT 000646033200053
Related Url isVersionOf https://doi.org/10.1093/ehjcr/ytaa264
JaLCDOI 10.18926/AMO/61909
FullText URL 75_2_249.pdf
Author Sun, Weiying| Shiode, Yusuke| Tokumasu, Kazuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Otsuka, Fumio| Morizane, Yuki|
Abstract A 79-year-old woman presented to our hospital with a 10-day history of gradually worsening binocular vision and severe backache. Further investigations revealed poor bilateral best-corrected visual acuities (BCVA), bilateral vitreous opacities, gray-white lesions scattered throughout the retina, and a left iliopsoas abscess on CT that later grew out methicillin-sensitive S. aureus. The abscess was drained and intravenous antibiotics were initiated, but the left eye additionally required intravitreal vancomycin. BCVA for both eyes normalized within 1 year. Intramuscular abscess should be considered as a possible primary lesion in cases of endogenous bacterial endophthalmitis.
Keywords endogenous bacterial endophthalmitis methicillin-sensitive Staphylococcus aureus iliopsoas abscess intravitreal injection vancomycin
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 249
End Page 253
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953434
NAID 120007029878
JaLCDOI 10.18926/AMO/61908
FullText URL 75_2_243.pdf
Author Tomita, Yusuke| Shimazu, Yosuke| Kawakami, Masato| Matsumoto, Hiroshi| Fujii, Kentaro| Kameda, Masahiro| Yasuhara, Takao| Suruga, Yasuki| Ota, Tomoyuki| Kimata, Yoshihiro| Kurozumi, Kazuhiko| Date, Isao|
Abstract Ventriculitis is a rare, serious complication of neurosurgery. A 59-year-old man who had undergone a craniotomy for a paranasal adenocarcinoma, developed a right frontal cystic lesion. We performed a bifrontal craniotomy to remove the lesion. The dura was repaired with non-vascularized free fascia lata in watertight fashion. Ventriculitis occurred 3 days postoperatively. Ventricular drainage, craniectomy, and endoscopic irrigation were undertaken to remove an abscess. The dura and the resection cavity were reconstructed using a vascularized anterolateral thigh adipofascial flap. His symptoms disappeared, indicating that endoscopic irrigation and reconstruction can effectively address ventriculitis even in patients in critical clinical condition.
Keywords ventriculitis surgical site infection intraventricular antimicrobial therapy anterior skull base surgery
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 243
End Page 248
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953433
NAID 120007029879
FullText URL fulltext.pdf
Author Asada, Saori| Nishii, Nobuhiro| Shinya, Takayoshi| Miyoshi, Akihito| Morimoto, Yoshimasa| Miyamoto, Masakazu| Nakagawa, Koji| Nakamura, Kazufumi| Morita, Hiroshi| Ito, Hiroshi|
Published Date 2021-03-04
Publication Title PLoS One
Volume volume16
Issue issue3
Publisher Public Library of Science
Start Page e0245502
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Asada et al.
File Version publisher
PubMed ID 33661956
DOI 10.1371/journal.pone.0245502
NAID 120007019113
Web of Science KeyUT 000626604100103
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0245502
JaLCDOI 10.18926/AMO/61431
FullText URL 75_1_31.pdf
Author Miyamaru, Satoru| Murakami, Daizo| Nishimoto, Kohei| Saito, Haruki| Miyamoto, Yusuke| Hirota, Kaoruko| Ise, Momoko| Orita, Yorihisa|
Abstract Although the lung is the most common site of distant metastases from head and neck squamous cell carcinoma (HNSCC), the number of reports about the effects of pulmonary metastasectomy for the treatment of lung metastasis from HNSCC is limited. Metachronous pulmonary metastases were detected in 45 HNSCC patients at Kumamoto University Hospital from 1998 to 2018. Twenty-two patients underwent an operative resection (Ope group) and 23 underwent chemotherapy (Chemo group). The 3-year overall survival (OS) rate and median OS were evaluated. The effects of adjuvant chemotherapy after pulmonary metastasectomy and of new drugs (cetuximab and nivolumab), in the chemo group were also assessed. The 3-year OS rates and median OS were: Ope, 66.1% and 31.5 months; Chemo, 39.7% and 18 months, respectively. In the Ope group, addi-tional recurrences were significantly fewer in the patients who underwent adjuvant chemotherapy post-surgery versus the patients who underwent surgery alone (p = 0.013). In the Chemo group, the 3-year OS rate of the patients who received new drugs was significantly better than that of the patients who did not (p = 0.021). Adjuvant chemotherapy after pulmonary metastasectomy may be a preferable treatment option for preventing recurrences. Cetuximab and nivolumab have a potential to improve OS.
Keywords pulmonary metastasis head and neck squamous cell carcinoma pulmonary metastasectomy adjuvant chemotherapy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-02
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 31
End Page 37
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649611
FullText URL fulltext.pdf
Author Masuda, Takahiko| Watanabe, Tsukasa| Beeks, Kjeld| Fujimoto, Hiroyuki| Hiraki, Takahiro| Kaino, Hiroyuki| Kitao, Shinji| Miyamoto, Yuki| Okai, Koichi| Sasao, Noboru| Seto, Makoto| Schumm, Thorsten| Shigekawa, Yudai| Tamasaku, Kenji| Uetake, Satoshi| Yamaguchi, Atsushi| Yoda, Yoshitaka| Yoshimi, Akihiro| Yoshimura, Koji|
Keywords X-ray diffraction energy calibration lattice constants rotary encoders nuclear resonant scattering
Published Date 2021-01
Publication Title Journal of Synchrotron Radiation
Volume volume28
Issue issue1
Publisher International Union of Crystallography
Start Page 111
End Page 119
ISSN 0909-0495
NCID AA11022317
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33399559
DOI 10.1107/S1600577520014526
Web of Science KeyUT 000605205600014
Related Url isVersionOf https://doi.org/10.1107/S1600577520014526