result 1284 件
| Title Alternative | Basic and clinical research regarding vascular endothelial function |
|---|---|
| FullText URL | 127_187.pdf |
| Author | Tsukahara, Hirokazu| |
| Keywords | アルギニン代謝 一酸化窒素 ガス生物学 血管内皮学 酸化ストレス |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-12-01 |
| Volume | volume127 |
| Issue | issue3 |
| Start Page | 187 |
| End Page | 195 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.187 |
| NAID | 130005116819 |
| JaLCDOI | 10.18926/AMO/53672 |
|---|---|
| FullText URL | 69_5_267.pdf |
| Author | Inada, Ryo| Nagasaka, Takeshi| Kondo, Yoshitaka| Watanabe, Ayako| Toshima, Toshiaki| Kubota, Nobuhito| Kikuchi, Satoru| Ishida, Michihiro| Kuroda, Shinji| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| Abstract | The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time. |
| Keywords | laparoscopic surgery total proctocolectomy open proctocolectomy ulcerative colitis case-matched study |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 267 |
| End Page | 273 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490023 |
| Web of Science KeyUT | 000365519600002 |
| Title Alternative | Successful laparoscopic resection of a cecal tumor in a 95-year-old man |
|---|---|
| FullText URL | 127_117.pdf |
| Author | Watanabe, Ayako| Inada, Ryo| Nagasaka, Takeshi| Yagi, Tomohiko| Matsumoto, Hijiri| Toshima, Toshiaki| Kikuchi, Satoru| Kuroda, Shinshi| Kondo, Yoshitaka| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| Abstract | We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients. |
| Keywords | 超高齢者（extremely elderly patient） 大腸癌（colorectal cancer） 腹腔鏡手術（laparoscopic surgery） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-08-03 |
| Volume | volume127 |
| Issue | issue2 |
| Start Page | 117 |
| End Page | 121 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.117 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.117 |
| NAID | 130005096253 |
| JaLCDOI | 10.18926/AMO/53337 |
|---|---|
| FullText URL | 69_2_87.pdf |
| Author | Murayama, Hidehiko| Nakata, Yusei| Kanazawa, Akane| Watanabe, Hirokazu| Shigemitsu, Yusuke| Iwasaki, Yuka| Tokorodani, Chiho| Miyazawa, Mari| Nishiuchi, Ritsuo| Kikkawa, Kiyoshi| |
| Abstract | Ventriculoperitoneal shunts (VPSs) are used for the treatment of hydrocephalus. Here we analyzed the outcomes of VPS placements in 24 infants to determine the risk factors for shunt failure. The infants had undergone the initial VPS operation in our hospital between March 2005 and December 2013. They were observed until the end of January 2014. We obtained Kaplan-Meier curves and performed a multivariate Cox regression analysis of shunt failure. Of the 24 cases, the median (range) values for gestational age, birth weight, and birth head circumference (HC) were 37 (27-39) wks, 2,736 (686-3,788) g, and 35.3 (23.0-45.3) cm, respectively. The total number of shunt procedures was 45. Shunt failure rates were 0.51/shunt and 0.0053/shunt/year. Shunt infection rates were 0.13/shunt and 0.0014/shunt/year. The Kaplan-Meier analysis revealed an increased risk for shunt failure in infants ＜1 month old or in the HC ＞90ｵtile. The Cox regression analysis yielded hazard ratios (HRs) of 2.93 (95ｵ confidence interval (CI), 0.96-10.95, p＝0.059) for age ＜1 month, and 4.46 (95ｵCI:1.20-28.91,p＝0.023) for the HC ＞90ｵtile. The multivariate Cox regression analysis showed adjusted HRs of 17.56 (95ｵCI:2.69-202.8, p＝0.001) for age ＜1 month, and 2.95 (95ｵCI:0.52-24.84, p＝0.228) for the HC ＞90ｵtile. Our findings thus revealed that the risk factors for shunt failure in infants include age ＜1 month at the initial VPS placement. |
| Keywords | head circumference shunt failure shunt infection ventriculoperitoneal shunt |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-04 |
| Volume | volume69 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 87 |
| End Page | 93 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25899630 |
| Web of Science KeyUT | 000353181700003 |
| Title Alternative | Cholelithiasis with a cholecystoduodenal fistula complicated with paroxysmal nocturnal hemoglobinuria |
|---|---|
| FullText URL | 127_35.pdf |
| Author | Kato, Takuya| Matsukawa, Hiroyoshi| Shiozaki, Shigehiro| Fuji, Tomokazu| Fujiwara, Yasuhiro| Ninomiya, Motoki| |
| Abstract | In cases of paroxysmal nocturnal hemoglobinuria (PNH), attention must be paid to potential complications such as thrombosis and hemolysis due to perioperative stress and infection from complement activation. Here we present the case of a 61-year-old Japanese woman with PNH. We made the diagnosis of PNH when she was 28 years old, and we administered repeated steroid medication and erythrocyte transfusion. The patient's cholecystocholedocholithiasis with a cholecystoduodenal fistula was diagnosed based on a survey of the right hypochondriac pain. We performed endoscopic nasobiliary drainage (ENBD) for the prophylaxis of perioperative infection, plus a cholecystectomy and fistulectomy. There were no complications, including hemolysis attack, infection, thrombosis with irrigation erythrocyte transfusion, steroid cover, or the need for heparin administration during the perioperative period. The reduction of the complement activation is necessary in the perioperative management of PNH patients. The prevention of the development of acidosis and hypoxemia, the selection of washed red blood cells, steroid use, appropriate infection measures and thrombosis prophylaxis are all important for the prevention of complications. |
| Keywords | 発作性夜間血色素尿症（PNH）（paroxysmal nocturnal hemoglobinuria (PNH)） 胆嚢十二指腸瘻（cholecystoduodenal fistula） 溶血発作（hemolysis） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-04-01 |
| Volume | volume127 |
| Issue | issue1 |
| Start Page | 35 |
| End Page | 39 |
| ISSN | 0030-1558 |
| Related Url | http://www.okayama-u.ac.jp/user/oma/ |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.35 |
| NAID | 130005068351 |
| Title Alternative | Surgically treated Zenker’s diverticulum： Diverticulectomy and cricopharyngeal myotomy |
|---|---|
| FullText URL | 127_19.pdf |
| Author | Ninomiya, Takayuki| Kanaya, Nobuhiko| Katsuda, Koh| Tanakaya, Kohji| Aoki, Hideki| Takeuchi, Hitoshi| |
| Abstract | Zenker's diverticulum is a very rare disease among gastorointestinal diverticulum. We report a case of Zenker's diverticulum successfully treated with diverticulectomy and cricophalyngial myotomy. A 71-year-old male complained of aspirating water for two years. He was diagnosed as Zenker's diverticulum. Due to his severe symptoms, the operation was performed in an open-neck approach. The left recurrent laryngeal nerve was identified and preserved. An incision was made in the diverticulum wall, and the internal diameter of normal cervical esophagus was measured. The diverticulum was then excised with an automatic suture device in the minor axis direction of the esophagus. A cricopharyngeal myotomy was conducted, because this muscle was fibrotic and stiffened. The patient's symptoms disappeared after the operation. Diverticulectomy and cricopharyngeal myotomy through an open-neck approach is a safe and reliable method that follows, direct access to the diverticulum and recurrent laryngeal nerve. |
| Keywords | Zenker憩室（Zenker’s diverticulum） 輪状咽頭筋切開術（cricopharyngeal myotomy） 頚部アプローチ（open-neck approach） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-04-01 |
| Volume | volume127 |
| Issue | issue1 |
| Start Page | 19 |
| End Page | 23 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.19 |
| NAID | 130005068344 |
| JaLCDOI | 10.18926/ESR/53194 |
|---|---|
| Title Alternative | Aerosol observation at Okayama with Skyradiometer and LIDAR |
| FullText URL | esr_021_1_013_021.pdf |
| Author | Nagamatsu, Sinpei| Egawa, Daiki| Tsukamoto, Osamu| |
| Abstract | Aerosol is one of the controlling parameter for the global climate and also effects on local health hazards. The measurement of the aerosol was originally carried out as in-situ sampling and mass weight measurement including chemical analysis. Recently, remote sensing method is applied as satellite remote sensing and surface based remote sensing. Skyradiometer and LIDAR are surface based remote sensing system. Skyradiometer measures solar radiation as direct and scattered solar radiation affected by aerosols. LIDAR emit laser beam upward and it is backscattered by overlying aerosols. The backscattered light is received by a telescope and vertical distributions of the aerosols are obtained. These measurements require atmospheric radiation physics. A Skyradiometer and a LIDAR were operated continuously at Okayama University campus and aerosol parameters were obtained from both of the system. Seasonal variations of the AOT (Aerosol Optical Thickness) and Angstrom parameter (α) are evaluated. During some dust events (e.g. yellow sand and PM2.5), time variations of these parameters were identified from both of the measurement system. |
| Keywords | Aerosol Skyradiometer LIDAR Aerosol Optical Thickness (AOT) |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2014-12-27 |
| Volume | volume21 |
| Issue | issue1 |
| Start Page | 13 |
| End Page | 21 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2014 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120005567873 |
| Author | Yasuba, Ken-ichiro| |
|---|---|
| Published Date | 2015-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume104 |
| Content Type | Departmental Bulletin Paper |
| Author | Kamimura, Kazuo| Nagata, Nozomu| Kikumoto, Mei| Sharmin, Sultana| Wakai, Satoshi| Kanao, Tadayoshi| |
|---|---|
| Published Date | 2015-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume104 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondo, Yoshitaka| Nagasaka, Takeshi| Kobayashi, Satoru| Kobayashi, Naoya| Fujiwara, Toshiyoshi| |
|---|---|
| Published Date | 2014-03 |
| Publication Title | Hepato-Gastroenterology |
| Volume | volume61 |
| Issue | issue130 |
| Content Type | Journal Article |
| Author | Yamada, Eiji| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Sakuma, Leon| Takaoka, Munenori| Yamada, Takako| Noma, Kazuhiro| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Tanabe, Shunsuke| Nagasaka, Takeshi| Fujiwara, Toshiyoshi| Naomoto, Yoshio| |
|---|---|
| Published Date | 2012-12 |
| Publication Title | Journal of Surgical Research |
| Volume | volume178 |
| Issue | issue2 |
| Content Type | Journal Article |
| Title Alternative | Giant rectal gastrointestinal stromal tumor successfully resected by abdominoperineal resection combined with posterior vaginal wall resection |
|---|---|
| FullText URL | 126_217.pdf |
| Author | Iwakawa, Kazuhide| Nishie, Manabu| Tokunaga, Naoyuki| Miyaso, Hideaki| Iwagaki, Hiromi| |
| Abstract | We report a case of giant rectal gastrointestinal stromal tumor (GIST) successfully resected by abdominoperineal resection combined with posterior vaginal wall resection. Our patient was a 79-year-old woman had been diagnosed as having von Recklinghausen disease at the age of 30 years. In 2006, a computed tomography (CT) scan revealed a tumor originating from the posterior wall of the rectum. In June 2010, she was admitted to our hospital with the chief complaint of bloody stool. A CT scan revealed a giant tumor that had increased to 9cm in size. Colonoscopy demonstrated a submucosal tumor, which was subsequently diagnosed by biopsy as a GIST. Due to the patient's continuous bleeding and abdominal pain, an emergent abdominoperineal resection was performed at that time. The tumor, which measured 8×9cm, was immunohistochemically positive for c-kit and CD34. Concomitant resection of the posterior wall of the vagina via the perineal approach provided a wide area to expose the tumor for a safe operation. The patient has been well with no sign of recurrence since the operation. This procedure is recommended as a useful approach for giant rectal GISTs or rectal cancer with invasion of the posterior pelvic wall. |
| Keywords | 巨大直腸GIST（giant rectal GIST） 腹会陰式直腸切断術（abdominoperineal resection） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 217 |
| End Page | 221 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.217 |
| NAID | 130004903245 |
| Author | MINOWA, Hirotsugu| MUNESAWA, Yoshiomi| SUZUKI, Kazuhiko| |
|---|---|
| Published Date | 2012-10-15 |
| Publication Title | 安全工学 |
| Volume | volume51 |
| Issue | issue5 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/52893 |
|---|---|
| FullText URL | 68_5_255.pdf |
| Author | Esumi, Satoru| Kawasaki, Yoichi| Gomita, Yutaka| Kitamura, Yoshihisa| Sendo, Toshiaki| |
| Abstract | Motivation incorporates several psychological aspects that produce reward-related and learning behaviors. Although reward-related behavior is reported to be mediated by the dopaminergic reward pathway, the involvement of dopaminergic systems in motivated behavior has not been fully clarified. Several experimental methodologies for motivational behavior have been reported, but pharmacological characteristics seem to vary among these methodologies. In this review, we attempt to summarize three main concepts:(1) the relationship of dopamine neuron physiology with motivated behavior, (2) the pharmacological characteristics of the runway intracranial self-stimulation model, and (3) the behavioral distinction of disparate motivated behaviors. |
| Keywords | motivation reward dopamine operant behavior intracranial self-stimulation |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-10 |
| Volume | volume68 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 255 |
| End Page | 262 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25338481 |
| Web of Science KeyUT | 000343269300001 |
| Author | MINOWA, Hirotsugu| MUNESAWA, Yoshiomi| HASHIMOTO, Kohei| |
|---|---|
| Published Date | 2014-10-15 |
| Publication Title | 安全工学 |
| Volume | volume53 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Ohnishi, Atsuyuki| Miyake, Yasuhiro| Matsushita, Hiroshi| Matsumoto, Kazuyuki| Takaki, Akinobu| Yasunaka, Tetsuya| Koike, Kazuko| Ikeda, Fusao| Shiraha, Hidenori| Nouso, Kazuhiro| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2012 |
| Publication Title | Digestion |
| Volume | volume86 |
| Issue | issue2 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/52658 |
|---|---|
| FullText URL | 68_3_171.pdf |
| Author | Hagiya, Hideharu| Matsumoto, Mitsuaki| Yamasawa, Takahiko| Haruki, Yuto| Otsuka, Fumio| |
| Abstract | A 79-year-old man who had undergone a right femoropopliteal (FP) bypass operation 6 weeks previously was diagnosed with vascular graft infection caused by Staphylococcus lugdunensis. Another FP bypass operation was performed, with long-term administration of antibiotics, and the patient eventually recovered well without any recurrences for over 2 years. Although S. lugdunens is classified as coagulase-negative Staphylococcus, its pathogenicity has been reported to be equal to that of S. aureus. Based on the literature review, the organism characteristically colonizes the inguinal area of human skin;thus, operations such as FP bypass grafting may place patients at a relatively high risk for infection by S. lugdunensis, a potentially high-pathogenicity organism. |
| Keywords | coagulase-negative Staphylococcus (CNS) femoropopliteal (FP) bypass Staphylococcus lugdunensis vacuum-assisted closure (VAC) therapy vascular graft infection (VGI) |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 171 |
| End Page | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942796 |
| Web of Science KeyUT | 000337655600007 |
| JaLCDOI | 10.18926/AMO/52407 |
|---|---|
| FullText URL | 68_2_111.pdf |
| Author | Shirakawa, Yasuhiro| Noma, Kazuhiro| Maeda, Naoaki| Katsube, Ryoichi| Tanabe, Shunsuke| Ohara, Toshiaki| Sakurama, Kazufumi| Fujiwara, Toshiyoshi| |
| Abstract | Thoracoscopic esophagectomy in the prone position (TEPP) might enable solo-surgery in cases requiring resection of the esophagus and the surrounding lymph nodes due to the associated advantages of good exposure of the surgical field and ergonomic considerations for the surgeon. However, no one approach can be for all patients requiring extensive lymphadenectomy. We recently developed an assistant-based procedure to standardize exposure of the surgical field. Patients were divided into 1 of 2 groups:a pre-standardization group (n＝37) and a post-standardization group (n＝28). The thoracoscopic operative time was significantly shorter (p＝0.0037) in the post-standardization group (n＝28; 267±31min) than in the pre-standardization group (n＝37;301±53min). Further, learning curve analysis using the moving average method showed stabilization of the thoracoscopic operative time after the standardization. No significant differences were found in the number of mediastinal lymph nodes dissected or intraoperative blood loss between the 2 groups. There were also no significant differences in the complication rate. Assistant-based surgery and standardization of the procedure resulted in a well-exposed and safe surgical field. TEPP decreased the operative time, even in patients requiring extensive lymphadenectomy. |
| Keywords | thoracoscopic esophagectomy prone position standardization |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-04 |
| Volume | volume68 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 111 |
| End Page | 117 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24743786 |
| Web of Science KeyUT | 000334652700006 |
| Author | Fujiwara, Y.| Yamada, T.| Naomoto, Y.| Yamatsuji, T.| Shirakawa, Y.| Tanabe, S.| Noma, K.| Kimura, T.| Aoki, H.| Matsukawa, H.| Kimura, M.| Nonaka, Y.| Sasaki, H.| Onoda, T.| Otawa, Y.| Takaoka, M.| Fukazawa, T.| Ohno, Y.| Fujiwara, T.| |
|---|---|
| Published Date | 2013-12 |
| Publication Title | Journal of Hospital Infection |
| Volume | volume85 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Morimoto, Nobutoshi| Abe, Koji| |
|---|---|
| Published Date | 2014-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume126 |
| Issue | issue1 |
| Content Type | Journal Article |
