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Author Shimamura, Yasunori| Inoue, Madoka| Ozawa, Masatugu| Kanazawa, Tomoko| Saitou, Taiichi| Nakahara, Ryuichi| Noda, Tomoyuki| Nishida, Keiichiro| Ozaki, Toshifumi|
Published Date 2011-08-01
Publication Title 岡山医学会雑誌
Volume volume123
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/46634
FullText URL 65_3_211.pdf
Author Nakanishi, Kazuo| Yamane, Kentarou| Tanaka, Masato| Misawa, Haruo| Saiga, Kenta| Ozaki, Toshifumi|
Abstract Here we report a case of surgery for kyphosis of the thoracolumbar spine in an elderly patient, in whom surgery was performed because the patient had developed intractable digestive symptoms. The case was that of a 76-year-old female with complaints of back pain and dysphagia. When videofluoroscopic examination (VF) of swallowing was performed in the cardia of the stomach, images that indicated stagnation and the reflux of food were observed. It was easier for the patient to swallow food in the extension position. We performed corrective fusion of the posterior spine. After the surgery, the kyphosis angle was improved to 27°, the patient's back pain was alleviated, and it became easier for the patient to swallow food. VF also showed that the patient's difficulties with the passage of food had improved. We believe that surgery is a good treatment option for cases of kyphosis with digestive symptoms and deteriorating activities of daily living (ADL), even in the absence of pain and paralysis. VF is also useful for performing evaluations before and after surgery.
Keywords kyphosis dysphagia videofluoroscopic examination of swallowing (VF) fusion
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2011-06
Volume volume65
Issue issue3
Publisher Okayama University Medical School
Start Page 211
End Page 214
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21709720
Web of Science KeyUT 000292017500009
JaLCDOI 10.18926/CTED/44375
Title Alternative A Study of Fraction Teaching for Changing it from as Quantity to as Number
FullText URL cted_001_037_046.pdf
Author Kurosaki, Toyoo| Marui, Daisuke|
Abstract 平成20年度告示の小学校学習指導要領が平成23年度から完全実施される。従前のゆとり教育における分数指導は、集中方式で指導が行われた。第4学年では分数概念を、第6学年では分数計算の指導が行われてきた。基礎的・基本的知識・技能の確かな習得を目指す新しい分数指導では集中方式を改め、スパイラル方式で指導が行われる。しかも、第2学年から分数指導が行われる。分数概念に関する指導の最重要課題は、「量としての分数」から「数としての分数」の移行を図り、確かな「数としての分数」の概念を習得させることにある。そこで、本研究では、「量としての分数」から「数としての分数」へどのような移行指導すれば「数としての分数概念」を確実に習得することができるのか、その指導のポイントを実践的、実証的に明らかにする。
Keywords 分数概念 (concept of fraction) 量分数 (quantitative fraction) 数としての分数 (fraction as number) 単位分数 (unit fraction)
Publication Title 岡山大学教師教育開発センター紀要
Published Date 2011-03-10
Volume volume1
Start Page 37
End Page 46
ISSN 2186-1323
language Japanese
Copyright Holders Copyright © 2011 岡山大学教師教育開発センター
File Version publisher
NAID 120002835649
JaLCDOI 10.18926/CTED/44374
Title Alternative A study on cultivation of moral execution with extracurricular activities
FullText URL cted_001_029_036.pdf
Author Sakuta, Kiyohiro| Kurosaki, Toyoo|
Abstract 社会の変動の激しい時代にあって,地域の大人とのつながり,学校での友だちとのつながりでさえ希薄になる傾向が進んでいる。望ましい人間関係がつくれなかったり,自分の目標を見失ったり,自分に自信を失ったりする子どもが増えている。こうした子ども達が望ましい人間関係を築くことができるようになるためには,日々の生活において他者,社会に積極的に関わり,人間としてのよりよい在り方を自覚し,よりよい生き方を求めていく中で,望ましい道徳性をはぐくむ必要がある。そこで,同年齢とふれあう学級活動や異年齢児童とふれあう学校行事などの特別活動を通じて,他者や社会に積極的に関わる道徳教育を行う。こうした体験的に自分の周りの人を思いやる心,正義や公正を重んじる心,協力し合う心をはぐくめば,社会性や相手の立場を思いやる心の大切さに気づき,望ましい人間関係を築き上げることができると考える。本研究では,特別活動との総合単元的道徳学習の実践事例をもとにして,子ども達の心の変革の要因を分析・考察し,道徳的実践力の育成の効果を検討する。
Keywords 学級経営 (classroom activities) 人間関係の充実 (human relations) 感動体験 (emotional experience) 自己実現 (self-realization)
Publication Title 岡山大学教師教育開発センター紀要
Published Date 2011-03-10
Volume volume1
Start Page 29
End Page 36
ISSN 2186-1323
language Japanese
Copyright Holders Copyright © 2011 岡山大学教師教育開発センター
File Version publisher
NAID 120002835648
JaLCDOI 10.18926/40875
Title Alternative Chinese Hosts' Intercultural Contact with Japanese International Students : Categorization of Recognition and Coping Based on the AUC·GS Learning Model
FullText URL hss_030_065_079.pdf
Author Okunishi, Yuri| Tanaka, Tomoko|
Abstract 日本人留学生と交流経験を持つ、中国人ホスト学生15名及び中国人ホストファミリー6名を対象として、異文化接触における認知と対応について半構造化面接を実施し、AUC-GS学習モデル(田中・中島,2006)に基づき分析を行った。異文化に対する「気づき(A段階)」「理解(U段階)」「対処(C段階)」の3段階につき、語りからこれらの有無を判断してカテゴリ分けを行った。異文化への気づきはあるが葛藤への理解はなく葛藤場面にも出会ったことがない、というカテゴリに最も多くのホストが分類された。従来から異文化交流の正統派であると考えられてきた、異文化への気づきと葛藤理解と葛藤対処の3段階全てが備わったカテゴリにも、4名の学生が認定された。しかし、異文化葛藤への対処の仕方は、日本人学生のそれとは異なる傾向が認められた。中国人ホストは、日本人学生が実践していたような他者視点に立った調整型の対処方法というよりは(奥西・田中,2009)、自己の視点を機軸とした寛容さの発露により解決を試みていた。
Publication Title 岡山大学大学院社会文化科学研究科紀要
Published Date 2010-11-24
Volume volume30
Start Page 65
End Page 79
ISSN 1881-1671
language Japanese
Copyright Holders 岡山大学大学院社会文化科学研究科
File Version publisher
NAID 120002674396
Author Ozaki, Toshifumi|
Published Date 1989-06
Publication Title 岡山医学会雑誌
Volume volume101
Issue issue5-6
Content Type Journal Article
Title Alternative Japanese guidelines for the treatment of hip fractures in the elderly
FullText URL 122_253.pdf
Author Noda, Tomoyuki| Ozaki, Toshifumi|
Publication Title 岡山医学会雑誌
Published Date 2010-12-01
Volume volume122
Issue issue3
Start Page 253
End Page 257
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2010 岡山医学会
File Version publisher
DOI 10.4044/joma.122.253
NAID 130004903185
Author Fujiwara, Kazuo| Endo, Hirosuke| Miyake, Yoshiaki| Ozaki, Toshifumi|
Published Date 2010-08-02
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue2
Content Type Journal Article
Author Furumatsu, Takayuki| Ozaki, Toshifumi| Asahara, Hiroshi|
Published Date 2010-08-02
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/40011
FullText URL fulltext.pdf
Author Honda, Mitsugi| Arita, Seizaburo| Mitani, Shigeru| Takeda, Yoshihiro| Ozaki, Toshifumi| Inamura, Keiji| Kanazawa, Susumu|
Abstract Plain X-ray radiography is frequently used for the diagnosis of developmental dislocation of the hip (DDH). The aim of this study was to construct a diagnostic support system for DDH based on clinical findings obtained from the X-ray images of 154 female infants with confirmed diagnoses made by orthopedists. The data for these subjects were divided into 2 groups. The Min-Max method of nonlinear analysis was applied to the data from Group 1 to construct the diagnostic support system based on the measurement of 4 items in X-ray images:the outward displacement rate, upward displacement rate, OE angle, and alpha angle. This system was then applied to the data from Group 2, and the results were compared between the 2 groups to verify the reliability of the system. We obtained good results that matched the confirmed diagnoses of orthopedists with an accuracy of 85.9%.
Keywords X-ray image developmental dislocation of the hip acetabular dysplasia radiographic findings nonlinear multivariate analysis infant hip joint diagnostic support system
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-06
Volume volume64
Issue issue3
Publisher Okayama University Medical School
Start Page 189
End Page 196
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 20596130
Web of Science KeyUT 000279094300005
JaLCDOI 10.18926/AMO/40007
FullText URL fulltext.pdf
Author Furumatsu, Takayuki| Ozaki, Toshifumi|
Abstract Epigenetics is an essential mechanism to control gene expression and fundamental cellular processes. DNA methylation in CpG-rich promoters correlates with gene silencing. Histone modification including histone acetylation and deacetylation determines the stability of the chromatin structure. Condensed chromatin (heterochromatin), which has a higher-order histone-DNA structure, prevents the access of transcriptional activators to their target genes. The fundamental unit of eukaryotic chromatin consists of 146 bp of DNA wrapped around a histone octamer. Posttranslational modifications of the histone tail and the chromatin remodeling complex disrupt histone-DNA contacts and induce nucleosome mobilization. Histone acetylation of specific lysine residues in the histone tail plays a crucial role in epigenetic regulation. Histone acetylation is a dynamic process regulated by the antagonistic actions of 2 families of enzymes - the histone acetyltransferases (HATs) and the histone deacetylases (HDACs). The balance between histone acetylation and deacetylation serves as a key epigenetic mechanism for transcription factor-dependent gene expression and the developmental process. We review emerging evidence that DNA methylation, histone acetylation modified by HAT and/or HDAC, and transcription factor-associated molecules contribute to a mechanism that can alter chromatin structure, gene expression, and cellular differentiation during chondrogenesis.
Keywords epigenetics DNA methylation histone acetylation and HAT histone deacetylation and HDAC chondrogenesis
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2010-06
Volume volume64
Issue issue3
Publisher Okayama University Medical School
Start Page 155
End Page 161
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 20596126
Web of Science KeyUT 000279094300001
Author Ito, Tatsuo| Ouchida, Mamoru| Morimoto, Yuki| Yoshida, Aki| Jitsumori, Yoshimi| Ozaki, Toshifumi| Sonobe, Hiroshi| Inoue, Hajime| Shimizu, Kenji|
Published Date 2005-06-28
Publication Title Cancer Letters
Volume volume224
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/32889
FullText URL fulltext.pdf
Author Nakanishi, Kazuo| Tanaka, Masato| Sugimoto, Yoshihisa| Ozaki, Toshifumi|
Abstract

We performed fixation using laminar screws in 2 patients in whom lateral mass screws, pedicle screws or transarticular screws could not be inserted. One was a 56-year-old woman who had anterior atlantoaxial subluxation (AAS). When a guide wire was inserted using an imaging guide, the hole bled massively. We thought the re-insertion of a guide wire or screw would thus increase the risk of vascular injury, so we used laminar screws. The other case was an 18-year-old man who had a hangman fracture. Preoperative magnetic resonance angiography showed occlusion of the left vertebral artery. A laminar screw was inserted into the patent side (i.e., the right side of C2). Cervical pedicle screws are the most biomechanically stable screws. However, their use carries a high risk of neurovascular complications during screw insertion, because the cervical pedicle is small and is adjacent laterally to the vertebral artery, medially to the spinal cord, and vertically to the nerve roots. Lateral mass screws are also reported to involve a risk of neurovascular injuries. The laminar screw method was thus thought to be useful, since arterial injuries could thus be avoided and it could also be used as a salvage modality for the previous misinsertion.

Keywords laminar screw neurovascular complications lateral mass screw pedicle screw transarticular
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2007-04
Volume volume61
Issue issue2
Publisher Okayama University Medical School
Start Page 115
End Page 119
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 17471313
Web of Science KeyUT 000245875600010
JaLCDOI 10.18926/AMO/32855
FullText URL fulltext.pdf
Author Shimamura, Yasunori| Nishida, Keiichiro| Imatani, Junya| Noda, Tomoyuki| Hashizume, Hiroyuki| Ohtsuka, Aiji| Ozaki, Toshifumi|
Abstract

We biomechanically evaluated the bone fixation rigidity of an ONI plate (Group I) during fixation of experimentally created transcondylar humerus fractures in cadaveric elbows, which are the most frequently observed humeral fractures in the elderly, and compared it with the rigidity achieved by 3 conventional fixation methods:an LCP reconstruction plate 3.5 using a locking mechanism (Group II), a conventional reconstruction plate 3.5 (CRP) with a cannulated cancellous screw (Group III), and a CRP with 2 cannulated cancellous screws (CS) in a crisscross orientation (Group IV). In the axial loading test, the mean failure loads were:Group I, 98.9+/-32.6;Group II, 108.5+/-27.2;Group III, 50.0+/-7.5;and Group IV, 34.5+/-12.2 (N). Group I fixations failed at a significantly higher load than those of Groups III and IV (p0.05). In the extension loading test, the mean failure loads were:Group I, 34.0+/-12.4;Group II, 51.0+/-14.8;Group III, 19.3+/-6.0;and Group IV, 14.7+/-3.1 (N). Group IV fixations showed a significantly lower failure load than those of Group I (p0.05). The fixation rigidities against mechanical loading by the ONI plate and LCP plate were comparable. These results suggested that an ONI system might be superior to the CRP and CS method, and comparable to the LCP method in terms of fixation rigidity for distal humerus fractures.

Keywords distal humerus fracture biomechanics internal fixation elderly
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-04
Volume volume64
Issue issue2
Publisher Okayama University Medical School
Start Page 115
End Page 120
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 20424666
Web of Science KeyUT 000276996900005
JaLCDOI 10.18926/AMO/32853
FullText URL fulltext.pdf
Author Endo, Hirosuke| Noda, Tomoyuki| Mitani, Shigeru| Nakahara, Ryuichi| Tetsunaga, Tomonori| Kunisada, Toshiyuki| Ozaki, Toshifumi|
Abstract

Femoroacetabular impingement (FAI) is a condition characterized by the impingement of the femur and acetabulum. In Japan, this disorder has become recognized gradually. Here we report a rare case of surgically treated FAI, associated with an osseous protrusion on the acetabulum of a 30-year-old female. Plain computed tomography (CT) and reconstructive 3D-CT images clearly demonstrated an anterolateral bony protrusion. Hip arthroscopy showed no degeneration of the cartilage on either the femoral or acetabular side, but degeneration at the edge of labrum was observed in the region of the bony protrusion. The complete removal of the bony protrusion under hip arthroscopy was thus considered impracticable, and a small skin incision was therefore made anteriorly to approach the acetabulum. The Short-Form 36-Item Health Survey (SF-36) revealed improvement in all scores.

Keywords femoroacetabular impingement bony protrusion Pincer type hip arthroscopy SF36
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2010-04
Volume volume64
Issue issue2
Publisher Okayama University Medical School
Start Page 149
End Page 154
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 20424671
Web of Science KeyUT 000276996900010
JaLCDOI 10.18926/AMO/32851
FullText URL fulltext.pdf
Author Shintani, Mai| Senda, Masuo| Takayanagi, Tomoko| Katayama, Yoshimi| Furusawa, Kazunari| Okutani, Tamami| Kataoka, Masaki| Ozaki, Toshifumi|
Abstract

To assess the effects of service dogs on health-related quality of life (HRQOL), we conducted a survey of 10 service dog owners using SF-36v2 (Medical Outcomes Study 36 Item Short-Form Health Survey Version 2.0) and compared it with a matched control group of people with physical disabilities who did not have service dogs but were eligible for one. The scores for mental health and role emotional of service dog owners were relatively high, and their mental component summary was higher than the general population norm. These results indicate that service dogs affect the mentality of their owners. The comparison with the control group indicated that service dogs alleviate the mental burden of daily activities, and subjectively improved the physical functioning of their owners. This study showed that service dogs have positive functional and mental effects on their disabled owners.

Keywords service dog HRQOL SF-36v2 people with physical disability
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-04
Volume volume64
Issue issue2
Publisher Okayama University Medical School
Start Page 109
End Page 113
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 20424665
Web of Science KeyUT 000276996900004
JaLCDOI 10.18926/AMO/32654
FullText URL fulltext.pdf
Author Ozaki, Toshifumi| Inoue, Hajime| Sugihara, Shinsuke| Sumii, Hiroshi|
Abstract

Radiological findings on the fate of grafted Kiel bone implants for the treatment of bone tumors were evaluated in 25 lesions. The mean follow-up period was 14.8 years, ranging from 5 to 21.8 years. We classified the radiological findings into 4 grades; Excellent (4 lesions), Good (14 lesions), Fair (2 lesions), and Poor (5 lesions). All cases of the Poor grade were polyostotic fibrous dysplasia. The younger the patient at the time of the operation, the more rapidly Kiel bone grafts tended to be incorporated. The grafted bone can become enmeshed in the structure of the recipient bed (Good or Excellent grades) within 10 years in most cases, except in polyostotic fibrous dysplasia.

Keywords xenogeneic bone bone grafting bone neoplasms
Amo Type Article
Publication Title Acta Medica Okayama
Published Date 1992-04
Volume volume46
Issue issue2
Publisher Okayama University Medical School
Start Page 87
End Page 92
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 1575062
Web of Science KeyUT A1992HR48400005
JaLCDOI 10.18926/AMO/32641
FullText URL fulltext.pdf
Author Ozaki, Toshifumi| Inoue, Hajime| Taguchi, Kohji| Sugihara, Shinsuke|
Abstract

We compared gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) enhanced T1-weighted images (T1-Gd) with the histopathological findings in 13 patients with bone or soft tissue sarcomas. Signal intensity of the viable tumor tissue was increased in T1-Gd in 92% of the patients. The necrotic or cystic areas in the tumor were not enhanced, rendering them distinctly. The degree of enhancement of the edematous area around the tumor was similar to or more marked than that of the tumor in 54% of the patients. Area showing inflammatory cells infiltration and edematous areas in the tumor tissue were also enhanced. Thus, the effect of preoperative chemotherapy in tumor tissues other than necrotic and cystic areas tended to be underestimated in T1-Gd. Its effect should be comprehensively evaluated based on not only T1-Gd but also T2-weighted images and findings of other imaging techniques.

Keywords gadolinium diethylenetriaminepentaacetic acid(DTPA) magnetic resonance(MR) bone neoplasms soft tissue neoplasms
Amo Type Article
Publication Title Acta Medica Okayama
Published Date 1992-12
Volume volume46
Issue issue6
Publisher Okayama University Medical School
Start Page 471
End Page 477
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 1485542
Web of Science KeyUT A1992KE49600010
JaLCDOI 10.18926/AMO/32621
FullText URL fulltext.pdf
Author Ozaki, Toshifumi| Inoue, Hajime| Sugihara, Shinsuke|
Abstract

We evaluated the surgical problems encountered during treatment of 14 patients with malignant tumors originating in the pelvic region at our department. The tumor involved the iliac bone in 6 patients, the ischial bone in 2, the pubic bone in 2, and the gluteal region in 4. Invasion to the sacrum was observed in 7 patients. Twelve patients underwent surgical procedures consisting of intralesional resection in 6, marginal resection in 3, and wide margin resection in 3. Six of the 7 patients with sacral invasion developed local recurrence. Two patients with chondrosarcoma and one with parosteal osteosarcoma survived for 4 or more years, but the mean survival period in those with high grade malignant tumors was 11 months. These findings indicate the difficulties encountered in the treatment of malignant pelvic tumors.

Keywords bone neoplasms soft tissue neoplasms malignant neoplasms pelvis surgical treatment
Amo Type Article
Publication Title Acta Medica Okayama
Published Date 1992-08
Volume volume46
Issue issue4
Publisher Okayama University Medical School
Start Page 265
End Page 271
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 1442150
Web of Science KeyUT A1992JL44200006
JaLCDOI 10.18926/AMO/31850
FullText URL fulltext.pdf
Author Ohmori, Takao| Endo, Hirosuke| Mitani, Shigeru| Minagawa, Hiroshi| Tetsunaga, Tomonori| Ozaki, Toshifumi|
Abstract

In 1957, Pavlik introduced the Pavlik harness as a useful treatment for developmental dislocation of the hip (DDH), and subsequent studies have documented favorable outcomes among patients treated with this device. However, there are only a few articles reporting how early radiographic measurements can be used to determine the prognosis after treatment with the Pavlik harness. In this study, 217 hips from 192 patients whose DDH treatment with the Pavlik harness was initiated before they were 6 months old and whose follow-up lasted at least 14 years (rate, 63.8%) were analyzed using measurements from radiographs taken immediately before and after harness treatment, and at 1, 2, and 3 years of age. Severin's classification at the final follow-up was I or II in 71.9% and III or IV in 28.1% of the hips, respectively. Avascular necrosis of the femoral head (AVN) was seen in 10% of the hips. Stepwise multiple regression analysis was performed to retrospectively determine whether any radiographic factors were related to the final classification as Severin I/II or III/IV. Receiver opera-ting characteristic (ROC) curves were drawn for these factors, and a Wiberg OE angle (Point O was the middle point of the proximal metaphyseal border of the femur) of 2 degrees on the 3-year radiographs was found to be the most useful screening value for judging the acetabular development of DDH cases after treatment with a Pavlik harness, with a sensitivity of 71% a specificity of 93%, and a likelihood ratio of 10.1.

Keywords developmental dislocation of the hip long-term follow up radiographic measurement stepwise multiple regression analysis acetabular development
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2009-06
Volume volume63
Issue issue3
Publisher Okayama University Medical School
Start Page 123
End Page 128
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
File Version publisher
Refereed True
PubMed ID 19571898
Web of Science KeyUT 000267388200001