Maeda, Yoshinobu - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

FullText URL	fulltext.pdf
Author	Katayama, Hideki\| Ichihara, Eiki\| Morita, Ayako\| Makimoto, Go\| Kagawa, Shunsuke\| Ishii, Ayano\| Tabata, Masahiro\| Maeda, Yoshinobu\|
Keywords	Cancer Alopecia Wig purchases Appearance care Patient support
Published Date	2025-03-15
Publication Title	Supportive Care in Cancer
Volume	volume33
Issue	issue4
Publisher	Springer Science and Business Media LLC
Start Page	283
ISSN	0941-4355
NCID	AA10996793
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40088298
DOI	10.1007/s00520-025-09318-8
Web of Science KeyUT	001446435900003
Related Url	isVersionOf https://doi.org/

Characteristics of oral mucositis in patients undergoing haploidentical stem cell transplantation with posttransplant cyclophosphamide: marked difference between busulfan and melphalan regimens

FullText URL	fulltext.pdf
Author	Ogura, Saki\| Soga, Yoshihiko\| Fujiwara, Hideaki\| Miura, Rumi\| Matsuoka, Ken-ichi\| Maeda, Yoshinobu\| Kuboki, Takuo\|
Keywords	Oral mucositis Hematopoietic cell transplantation Posttransplant cyclophosphamide Busulfan Melphalan
Published Date	2025-03-05
Publication Title	Supportive Care in Cancer
Volume	volume33
Issue	issue4
Publisher	Springer Science and Business Media LLC
Start Page	252
ISSN	0941-4355
NCID	AA10996793
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40045113
DOI	10.1007/s00520-025-09313-z
Web of Science KeyUT	001439702300001
Related Url	isVersionOf https://doi.org/10.1007/s00520-025-09313-z

A randomized controlled trial of conventional GVHD prophylaxis with or without teprenone for the prevention of severe acute GVHD

FullText URL	fulltext.pdf
Author	Kitamura, Wataru\| Fujii, Keiko\| Tsuge, Mitsuru\| Mitsuhashi, Toshiharu\| Kobayashi, Hiroki\| Kamoi, Chihiro\| Yamamoto, Akira\| Kondo, Takumi\| Seike, Keisuke\| Fujiwara, Hideaki\| Asada, Noboru\| Ennishi, Daisuke\| Matsuoka, Ken-ichi\| Fujii, Nobuharu\| Maeda, Yoshinobu\|
Keywords	Allogeneic hematopoietic stem cell transplantation Graft-versus-host disease Teprenone Oxidative stress Interleukin-33
Note	The version of record of this article, first published in Annals of Hematology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00277-025-06269-2\|
Published Date	2025-02-24
Publication Title	Annals of Hematology
Publisher	Springer Science and Business Media LLC
ISSN	0939-5555
NCID	AA1079712X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	39994018
DOI	10.1007/s00277-025-06269-2
Web of Science KeyUT	001429419900001
Related Url	isVersionOf https://doi.org/10.1007/s00277-025-06269-2

Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease

FullText URL	fulltext20250304-01.pdf
Author	Nishimura, Yoshito\| Fajgenbaum, David C.\| Pierson, Sheila K.\| Iwaki, Noriko\| Nishikori, Asami\| Kawano, Mitsuhiro\| Nakamura, Naoya\| Izutsu, Koji\| Takeuchi, Kengo\| Nishimura, Midori Filiz\| Maeda, Yoshinobu\| Otsuka, Fumio\| Yoshizaki, Kazuyuki\| Oksenhendler, Eric\| van Rhee, Frits\| Sato, Yasuharu\|
Note	This is the peer reviewed version of the following article: [Nishimura Y, Fajgenbaum DC, Pierson SK, et al. Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease. Am J Hematol. 2021; 96(10): 1241-1252. https://doi.org/10.1002/ajh.26292], which has been published in final form at [https://doi.org/10.1002/ajh.26292]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
Published Date	2021-07-28
Publication Title	American Journal of Hematology
Volume	volume96
Issue	issue10
Publisher	Wiley
Start Page	1241
End Page	1252
ISSN	0361-8609
NCID	AA00520673
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Wiley Periodicals LLC.
File Version	author
PubMed ID	34265103
DOI	10.1002/ajh.26292
Web of Science KeyUT	000678183100001
Related Url	isVersionOf https://doi.org/10.1002/ajh.26292

Plasma S100A8/A9 level predicts response to immune checkpoint inhibitors in patients with advanced non-small cell lung cancer

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Author	Kuribayashi, Tadahiro\| Kinoshita, Rie\| Ninomiya, Kiichiro\| Makimoto, Go\| Kubo, Toshio\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Toyooka, Shinichi\| Sakaguchi, Masakiyo\| Ohashi, Kadoaki\|
Keywords	S100A8/A9 Lung cancer Immune checkpoint inhibitors
Note	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-025-87232-z\|
Published Date	2025-01-20
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	2577
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	39833332
DOI	10.1038/s41598-025-87232-z
Web of Science KeyUT	001400880600002
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-87232-z

Frequency and Significance of Body Weight Loss During Immunochemotherapy in Patients with Advanced Non-Small Cell Lung Cancer

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Author	Taoka, Masataka\| Ichihara, Eiki\| Yokoyama, Toshihide\| Inoue, Koji\| Tamura, Tomoki\| Sato, Akiko\| Oda, Naohiro\| Kano, Hirohisa\| Nakamura, Kayo\| Kawai, Haruyuki\| Inoue, Masaaki\| Ochi, Nobuaki\| Fujimoto, Nobukazu\| Ichikawa, Hirohisa\| Ando, Chihiro\| Oze, Isao\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Hotta, Katsuyuki\|
Keywords	non-small cell lung cancer body weight loss immune checkpoint inhibitors chemotherapy
Published Date	2024-12-06
Publication Title	Cancers
Volume	volume16
Issue	issue23
Publisher	MDPI
Start Page	4089
ISSN	2072-6694
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	39682275
DOI	10.3390/cancers16234089
Web of Science KeyUT	001376843000001
Related Url	isVersionOf https://doi.org/10.3390/cancers16234089

Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma

FullText URL	fulltext.pdf
Author	Inukai-Motokura, Yumi\| Ninomiya, Kiichiro\| Baba, Takahiro\| Omori, Hiroki\| Takeguchi, Tetsuya\| Uno, Mari\| Ayada, Yoshiyuki\| Tanaka, Takehiro\| Maeda, Yoshinobu\| Ohashi, Kadoaki\|
Keywords	Pulmonary sclerosing pneumocytoma Ipilimumab Nivolumab Programmed cell death ligand 1 Case report
Published Date	2024-11-29
Publication Title	International Cancer Conference Journal
Volume	volume14
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	60
End Page	63
ISSN	2192-3183
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
DOI	10.1007/s13691-024-00737-8
Web of Science KeyUT	001366705400001
Related Url	isVersionOf https://doi.org/10.1007/s13691-024-00737-8

The Clinical Significance of Interstitial Pneumonia with Autoimmune Features in Cryptogenic Organizing Pneumonia: A Prospective Multicenter Observational Study

FullText URL	fulltext.pdf
Author	Higo, Hisao\| Ichikawa, Hirohisa\| Arakawa, Yukako\| Mori, Yoshihiro\| Tamura, Tomoki\| Kuyama, Shoichi\| Matsumoto, Chiaki\| Sugimoto, Keisuke\| Hamada, Noboru\| Suwaki, Toshimitsu\| Itano, Junko\| Tanimoto, Yasushi\| Senoo, Satoru\| Taniguchi, Akihiko\| Inukai, Yumi\| Arita, Machiko\| Makimoto, Satoko\| Kojima, Katsuhide\| Matsushita, Takashi\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Keywords	interstitial pneumonia with autoimmune features cryptogenic organizing pneumonia bronchoalveolar lavage prospective multicenter observational study connective tissue disease
Published Date	2024-11-15
Publication Title	Journal of Clinical Medicine
Volume	volume13
Issue	issue22
Publisher	MDPI
Start Page	6870
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
DOI	10.3390/jcm13226870
Web of Science KeyUT	001365308300001
Related Url	isVersionOf https://doi.org/10.3390/jcm13226870

A Prompt Diagnosis and Treatment of a Case of Nuclear Protein of the Testis Carcinoma Characterized by a Bronchial Lesion and High Serum Alpha-fetoprotein Level Following Genomic Testing

FullText URL	fulltext.pdf
Author	Matsuura, Hiroaki\| Makimoto, Go\| Oda, Naohiro\| Ninomiya, Kiichiro\| Higo, Hisao\| Fujii, Masanori\| Rai, Kammei\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\|
Keywords	NUT carcinoma BRD4-NUTM1 lung cancer alpha-fetoprotein (AFP) immune checkpoint inhibitor
Published Date	2024-10-01
Publication Title	Internal Medicine
Volume	volume63
Issue	issue19
Publisher	Japanese Society of Internal Medicine
Start Page	2655
End Page	2660
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	38403772
DOI	10.2169/internalmedicine.2938-23
Web of Science KeyUT	001344217900013
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.2938-23

Enhancing Medical Interview Skills Through AI-Simulated PatientInteractions:Nonrandomized Controlled Trial

FullText URL	fulltext.pdf
Author	Yamamoto, Akira\| Koda, Masahide\| Ogawa, Hiroko\| Miyoshi, Tomoko\| Maeda, Yoshinobu\| Otsuka, Fumio\| Ino, Hideo\|
Keywords	medical interview generative pretrained transformer large language model simulation-based learning OSCE artificial intelligence medical education simulated patients nonrandomized controlled trial
Published Date	2024-09-23
Publication Title	JMIR Medical Education
Volume	volume10
Publisher	JMIR Publications
Start Page	e58753
ISSN	2369-3762
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Akira Yamamoto, Masahide Koda, Hiroko Ogawa, Tomoko Miyoshi, Yoshinobu Maeda, Fumio Otsuka, Hideo Ino.
File Version	publisher
PubMed ID	39312284
DOI	10.2196/58753
Web of Science KeyUT	001334427000001
Related Url	isVersionOf https://doi.org/10.2196/58753

Response to Imatinib in a Patient With Gastric Adenocarcinoma With KIT Q556_K558 In-Frame Deletion: A Case Report

Author	Ninomiya, Kiichiro\| Ennishi, Daisuke\| Okamoto, Kunio\| Ando, Midori\| Nakamura, Satoko\| Tomida, Shuta\| Ayada, Yoshiyuki\| Makimoto, Go\| Ichihara, Eiki\| Okita, Natsuko\| Toyooka, Shinichi\| Maeda, Yoshinobu\| Tabata, Masahiro\|
Note	This is an Accepted Manuscript of an article published by American Society of Clinical Oncology (ASCO).\| This fulltext file will be available in Sep. 2025.\|
Published Date	2024-09-19
Publication Title	JCO Precision Oncology
Volume	volume8
Publisher	American Society of Clinical Oncology (ASCO)
Start Page	e2400228
ISSN	2473-4284
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by American Society of Clinical Oncology.
File Version	author
PubMed ID	39298692
DOI	10.1200/po.24.00228
Web of Science KeyUT	001328214400001
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Protracted coronavirus disease 2019 after chimeric antigen receptor-T cell therapy successfully treated with sequential multidrug therapy

FullText URL	fulltext.pdf
Author	Yamashita, Masahiro\| Higo, Hisao\| Fujii, Nobuharu\| Matsumoto, Chiaki\| Makimoto, Go\| Ninomiya, Kiichiro\| Fujii, Masanori\| Rai, Kammei\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Keywords	Chimeric antigen receptor-T cell therapy Coronavirus disease 2019 Multidrug therapy Organizing pneumonia
Published Date	2024
Publication Title	Respiratory Medicine Case Reports
Volume	volume51
Publisher	Elsevier
Start Page	102104
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
DOI	10.1016/j.rmcr.2024.102104
Web of Science KeyUT	001307936800001
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2024.102104

A randomized, open-label phase II study on the preventive effect of goshajinkigan against peripheral neuropathy induced by paclitaxel-containing chemotherapy: The OLCSG2101 study protocol

Author	Nakamura, Naoki\| Makimoto, Go\| Tanaka, Takaaki\| Kato, Yuka\| Oze, Isao\| Kozuki, Toshiyuki\| Yokoyama, Toshihide\| Ichikawa, Hirohisa\| Kuyama, Shoichi\| Hara, Naofumi\| Maeda, Yoshinobu\| Hotta, Katsuyuki\|
Keywords	Kampo CIPN prophylaxis neuropathy taxane
Note	© 2024 The Japanese Respiratory Society. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/\| This fulltext file will be available in Aug. 2025.\|
Published Date	2024-09
Publication Title	Respiratory Investigation
Volume	volume62
Issue	issue5
Publisher	Elsevier BV
Start Page	897
End Page	900
ISSN	2212-5345
NCID	AA12579673
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Japanese Respiratory Society.
File Version	author
PubMed ID	39182943
DOI	10.1016/j.resinv.2024.07.017
Web of Science KeyUT	001292150300001
Related Url	isVersionOf https://doi.org/10.1016/j.resinv.2024.07.017

Increased Oxidative Stress and Decreased Citrulline in Blood Associated with Severe Novel Coronavirus Pneumonia in Adult Patients

FullText URL	fulltext.pdf
Author	Tsuge, Mitsuru\| Ichihara, Eiki\| Hasegawa, Kou\| Kudo, Kenichiro\| Tanimoto, Yasushi\| Nouso, Kazuhiro\| Oda, Naohiro\| Mitsumune, Sho\| Kimura, Goro\| Yamada, Haruto\| Takata, Ichiro\| Mitsuhashi, Toshiharu\| Taniguchi, Akihiko\| Tsukahara, Kohei\| Aokage, Toshiyuki\| Hagiya, Hideharu\| Toyooka, Shinichi\| Tsukahara, Hirokazu\| Maeda, Yoshinobu\|
Keywords	novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
Published Date	2024-07-31
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue15
Publisher	MDPI
Start Page	8370
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	39125944
DOI	10.3390/ijms25158370
Web of Science KeyUT	001286890700001
Related Url	isVersionOf https://doi.org/10.3390/ijms25158370

Combination of reduced post-transplant cyclophosphamide and early tacrolimus initiation increases the incidence of chronic graft-versus-host disease in human leukocyte antigen-haploidentical peripheral blood stem-cell transplantation

FullText URL	fulltext.pdf
Author	Terao, Toshiki\| Kondo, Takumi\| Nakamura, Makoto\| Takasuka, Hiroki\| Fujiwara, Hideaki\| Asada, Noboru\| Ennishi, Daisuke\| Nishimori, Hisakazu\| Fujii, Keiko\| Fujii, Nobuharu\| Maeda, Yoshinobu\| Matsuoka, Ken-Ichi\|
Keywords	chronic GVHD haploidentical hematopoietic stem-cell transplantation PTCy tacrolimus
Published Date	2024-06-19
Publication Title	eJHaem
Volume	volume5
Issue	issue4
Publisher	Wiley
Start Page	810
End Page	814
ISSN	2688-6146
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Author(s).
File Version	publisher
DOI	10.1002/jha2.962
Web of Science KeyUT	001250969300001
Related Url	isVersionOf https://doi.org/10.1002/jha2.962

Severe Cytokine Release Syndrome and Immune Effector Cell-associated Neurotoxicity Syndrome in a Man Receiving Immune Checkpoint Inhibitors for Lung Cancer

FullText URL	fulltext20240531-01.pdf
Author	Tanaka, Takaaki\| Taoka, Masataka\| Makimoto, Go\| Ninomiya, Kiichiro\| Higo, Hisao\| Fujii, Masanori\| Ichihara, Eiki\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\|
Keywords	immune checkpoint inhibitor nivolumab ipilimumab cytokine release syndrome immune effector cell-associated neurotoxicity syndrome
Published Date	2024-05-01
Publication Title	Internal Medicine
Volume	volume63
Issue	issue9
Publisher	Japanese Society of Internal Medicine
Start Page	1261
End Page	1267
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	37722894
DOI	10.2169/internalmedicine.2429-23
Web of Science KeyUT	001223220900001
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.2429-23

Concomitant osimertinib and antituberculosis therapy in an elderly patient with EGFR-mutated lung cancer and pulmonary tuberculosis: A case report

FullText URL	fulltext.pdf
Author	Matsuura, Hiroaki\| Higo, Hisao\| Kuribayashi, Tadahiro\| Tamaoki, Akihiko\| Nakasuka, Takamasa\| Uno, Mari\| Makimoto, Go\| Ninomiya, Kiichiro\| Fujii, Masanori\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Miyahara, Nobuaki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\| Ohashi, Kadoaki\|
Keywords	case report EGFR-mutated lung cancer osimertinib pulmonary tuberculosis rifampicin
Published Date	2024-05-02
Publication Title	Thoracic Cancer
Volume	volume15
Issue	issue17
Publisher	Wiley
Start Page	1390
End Page	1394
ISSN	1759-7706
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	38698706
DOI	10.1111/1759-7714.15324
Web of Science KeyUT	001216948400001
Related Url	isVersionOf https://doi.org/10.1111/1759-7714.15324

Spontaneous regression of multiple solitary plasmacytoma harboring Epstein–Barr virus: a case report and literature review

FullText URL	fulltext20240508-02.pdf fig20240508-02.pdf table20240508-02.pdf
Author	Kitamura, Wataru\| Kobayashi, Hiroki\| Noda, Minori\| Iseki, Akiko\| Sato, Yumi\| Maeda, Yoshinobu\| Kuyama, Shoichi\|
Keywords	Plasmacytoma Epstein–Barr virus Spontaneous regression
Note	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s12185-024-03765-5\| This fulltext file will be available in Apr. 2025.\|
Published Date	2024-04-15
Publication Title	International Journal of Hematology
Volume	volume120
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	128
End Page	134
ISSN	0925-5710
NCID	AA10797094
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Japanese Society of Hematology 2024
File Version	author
PubMed ID	38619657
DOI	10.1007/s12185-024-03765-5
Web of Science KeyUT	001204755500002
Related Url	isVersionOf https://doi.org/10.1007/s12185-024-03765-5

CDK4/6 signaling attenuates the effect of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

FullText URL	fulltext.pdf
Author	Hara, Naofumi\| Ichihara, Eiki\| Kano, Hirohisa\| Ando, Chihiro\| Morita, Ayako\| Nishi, Tatsuya\| Okawa, Sachi\| Nakasuka, Takamasa\| Hirabae, Atsuko\| Abe, Masaya\| Asada, Noboru\| Ninomiya, Kiichiro\| Makimoto, Go\| Fujii, Masanori\| Kubo, Toshio\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	Epidermal growth factor receptor (EGFR) non-small cell lung cancer (NSCLC) cell cycle CDK4/6 inhibitor
Published Date	2023-10-31
Publication Title	Translational Lung Cancer Research
Volume	volume12
Issue	issue10
Publisher	AME Publishing Company
ISSN	2218-6751
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Translational Lung Cancer Research.
File Version	publisher
PubMed ID	38025818
DOI	10.21037/tlcr-23-99
Web of Science KeyUT	001091030600001
Related Url	isVersionOf https://doi.org/10.21037/tlcr-23-99

Sigle Agent of Posttransplant Cyclophosphamide Without Calcineurin Inhibitor Controls Severity of Experimental Chronic GVHD

JaLCDOI	10.18926/AMO/66915
FullText URL	78_2_123.pdf
Author	Saeki, Kyosuke\| Fujiwara, Hideaki\| Seike, Keisuke\| Kuroi, Taiga\| Nishimori, Hisakazu\| Tanaka, Takehiro\| Matsuoka, Ken-ichi\| Fujii, Nobuharu\| Maeda, Yoshinobu\|
Abstract	Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT.
Keywords	GVHD posttransplant cyclophosphamide hematopoietic cell transplantation HLA-identical
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2024-04
Volume	volume78
Issue	issue2
Publisher	Okayama University Medical School
Start Page	123
End Page	134
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2024 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	38688830
Web of Science KeyUT	001229151800004