Maeda, Yoshinobu - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Prevention of non-infectious pulmonary complications after intra-bone marrow stem cell transplantation in mice

FullText URL	fulltext.pdf
Author	Yamasuji-Maeda, Yoshiko\| Nishimori, Hisakazu\| Seike, Keisuke\| Yamamoto, Akira\| Fujiwara, Hideaki\| Kuroi, Taiga\| Saeki, Kyosuke\| Fujinaga, Haruko\| Okamoto, Sachiyo\| Matsuoka, Ken-Ichi\| Fujii, Nobuharu\| Tanaka, Takehiro\| Fujii, Masahiro\| Mominoki, Katsumi\| Kanekura, Takuro\| Maeda, Yoshinobu\|
Published Date	2022-09-09
Publication Title	PLOS One
Volume	volume17
Issue	issue9
Publisher	Public Library Science
Start Page	e0273749
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Yamasuji-Maeda et al.
File Version	publisher
PubMed ID	36084023
DOI	10.1371/journal.pone.0273749
Web of Science KeyUT	000892051000058
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0273749

The Effect of Pleural Effusion on Prognosis in Patients with Non-Small Cell Lung Cancer Undergoing Immunochemotherapy: A Retrospective Observational Study

FullText URL	fulltext.pdf
Author	Nishimura, Tomoka\| Ichihara, Eiki\| Yokoyama, Toshihide\| Inoue, Koji\| Tamura, Tomoki\| Sato, Ken\| Oda, Naohiro\| Kano, Hirohisa\| Kishino, Daizo\| Kawai, Haruyuki\| Inoue, Masaaki\| Ochi, Nobuaki\| Fujimoto, Nobukazu\| Ichikawa, Hirohisa\| Ando, Chihiro\| Hotta, Katsuyuki\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	pleural effusion non-small cell carcinoma immune checkpoint inhibitors
Published Date	2022-12-14
Publication Title	Cancers
Volume	volume14
Issue	issue24
Publisher	MDPI
Start Page	6184
ISSN	2072-6694
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	36551668
DOI	10.3390/cancers14246184
Web of Science KeyUT	000900618600001
Related Url	isVersionOf https://doi.org/10.3390/cancers14246184

Neuropeptide Y Antagonizes Development of Pulmonary Fibrosis through IL-1β Inhibition

FullText URL	fulltext20221223-3.pdf NA_Itano_Fig.pdf supl20221223-3.pdf NA_Itano_Supl.pdf
Author	Itano, Junko\| Taniguchi, Akihiko\| Senoo, Satoru\| Asada, Noboru\| Gion, Yuka\| Egusa, Yuria\| Guo, Lili\| Oda, Naohiro\| Araki, Kota\| Sato, Yasuharu\| Toyooka, Shinichi\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Miyahara, Nobuaki\|
Keywords	idiopathic pulmonary fibrosis NPY IL-1 beta; bleomycin bronchial epithelial cells
Note	Originally Published in:Itano J, Taniguchi A, Senoo S, Asada N, Gion Y, Egusa Y, Guo L, Oda N, Araki K, Sato Y, Toyooka S, Kiura K, Maeda Y, Miyahara N. Neuropeptide Y Antagonizes Development of Pulmonary Fibrosis through IL-1β Inhibition. Am J Respir Cell Mol Biol. 2022 Dec;67(6):654-665. DOI: 10.1165/rcmb.2021-0542OC Copyright © 2022 by the American Thoracic Society The final publication is available at https://doi.org/10.1165/rcmb.2021-0542OC \| This full-text will be available in Dec. 2023.\|
Published Date	2022-12
Publication Title	American Journal of Respiratory Cell and Molecular Biology
Volume	volume67
Issue	issue6
Publisher	American Thoracic Society
Start Page	654
End Page	665
ISSN	1044-1549
NCID	AA10707251
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the American Thoracic Society
File Version	author
PubMed ID	36122332
DOI	10.1165/rcmb.2021-0542oc
Web of Science KeyUT	000891796900010
Related Url	isVersionOf https://doi.org/10.1165/rcmb.2021-0542oc

Successful and Prompt Treatment with Tepotinib for Lung Adenocarcinoma Harboring MET Exon 14 Skipping Mutation Combined with Lung Abscess Formation: A Case Report

FullText URL	fulltext.pdf
Author	Makimoto, Go\| Shimonishi, Atsushi\| Ohashi, Kadoaki\| Ninomiya, Kiichiro\| Higo, Hisao\| Kato, Yuka\| Fujii, Masanori\| Kubo, Toshio\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	MET Tepotinib Non-small-cell lung cancer
Published Date	2022
Publication Title	Case Reports In Oncology
Volume	volume15
Issue	issue2
Publisher	Karger
Start Page	494
End Page	498
ISSN	1662-6575
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Author(s).
File Version	publisher
PubMed ID	35702678
DOI	10.1159/000524326
Web of Science KeyUT	000864085100005
Related Url	isVersionOf https://doi.org/10.1159/000524326

Responses of regulatory and effector T-cells to low-dose interleukin-2 differ depending on the immune environment after allogeneic stem cell transplantation

FullText URL	fulltext.pdf
Author	Meguri, Yusuke\| Asano, Takeru\| Yoshioka, Takanori\| Iwamoto, Miki\| Ikegawa, Shuntaro\| Sugiura, Hiroyuki\| Kishi, Yuriko\| Nakamura, Makoto\| Sando, Yasuhisa\| Kondo, Takumi\| Sumii, Yuichi\| Maeda, Yoshinobu\| Matsuoka, Ken-Ichi\|
Keywords	regulatory T cell low-dose interleukin-2 therapy graft-versus-host disease graft-versus-leukemia effect transplantation tolerance
Published Date	2022-08-02
Publication Title	Frontiers In Immunology
Volume	volume13
Publisher	Frontiers Media
Start Page	891925
ISSN	1664-3224
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 Meguri, Asano, Yoshioka, Iwamoto, Ikegawa, Sugiura, Kishi, Nakamura, Sando, Kondo, Sumii, Maeda and Matsuoka.
File Version	publisher
PubMed ID	35983059
DOI	10.3389/fimmu.2022.891925
Web of Science KeyUT	000844642000001
Related Url	isVersionOf https://doi.org/10.3389/fimmu.2022.891925

Dasatinib-induced massive left chylothorax in a patient with chronic myeloid leukemia

FullText URL	fulltext.pdf
Author	Makimoto, Go\| Misawa, Mahito\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	Chronic myeloid leukemia Chylothorax Dasatinib
Published Date	2022
Publication Title	Respiratory Medicine Case Reports
Volume	volume37
Publisher	Elsevier
Start Page	101662
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Authors.
File Version	publisher
PubMed ID	35585905
DOI	10.1016/j.rmcr.2022.101662
Web of Science KeyUT	000807403400006
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2022.101662

Transformed diffuse large B-cell lymphoma from marginal zone lymphoma in the anterior mediastinum: A case report and review of the literature

FullText URL	fulltext.pdf
Author	Kitamura, Wataru\| Asada, Noboru\| Tabata, Tetsuya\| Shibata, Rei\| Nishi, Tatsuya\| Kato, Yuka\| Takasuka, Hiroki\| Fujiwara, Hideaki\| Ennishi, Daisuke\| Nishimori, Hisakazu\| Fujii, Nobuharu\| Matsuoka, Ken-Ichi\| Kiura, Katsuyuki\| Yoshino, Tadashi\| Maeda, Yoshinobu\|
Keywords	marginal zone lymphoma diffuse large B-cell lymphoma anterior mediastinum cystic lesions
Published Date	2022
Publication Title	Journal Of Clinical And Experimental Hematopatholo
Volume	volume62
Issue	issue1
Publisher	The Japanese Society for Lymphoreticular Tissue Research
Start Page	35
End Page	40
ISSN	1346-4280
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society for Lymphoreticular Tissue Research
File Version	publisher
PubMed ID	34840205
DOI	10.3960/jslrt.21010
Web of Science KeyUT	000766876600003
Related Url	isVersionOf https://doi.org/10.3960/jslrt.21010

Pulmonary Aspergilloma and Allergic Bronchopulmonary Aspergillosis Following the 2018 Heavy Rain Event in Western Japan

FullText URL	fulltext.pdf
Author	Ando, Eri\| Nakasuka, Takamasa\| Kubo, Toshio\| Taniguchi, Akihiko\| Ninomiya, Kiichiro\| Kato, Yuka\| Ichihara, Eiki\| Ohashi, Kadoaki\| Rai, Kammei\| Hotta, Katsuyuki\| Yamane, Masaomi\| Miyahara, Nobuaki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	pulmonary aspergilloma allergic bronchopulmonary aspergillosis disaster
Published Date	2022-02-01
Publication Title	Internal Medicine
Volume	volume61
Issue	issue3
Publisher	JAPAN SOC INTERNAL MEDICINE
Start Page	379
End Page	383
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	34373373
DOI	10.2169/internalmedicine.7124-21
Web of Science KeyUT	000752787300015
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.7124-21

Identification of targetable kinases in idiopathic pulmonary fibrosis

FullText URL	fulltext.pdf
Author	Higo, Hisao\| Ohashi, Kadoaki\| Tomida, Shuta\| Okawa, Sachi\| Yamamoto, Hiromasa\| Sugimoto, Seiichiro\| Senoo, Satoru\| Makimoto, Go\| Ninomiya, Kiichiro\| Nakasuka, Takamasa\| Nishii, Kazuya\| Taniguchi, Akihiko\| Kubo, Toshio\| Ichihara, Eiki\| Hotta, Katsuyuki\| Miyahara, Nobuaki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kiura, Katsuyuki\|
Keywords	Idiopathic pulmonary fibrosis RNA sequencing Molecular therapeutic target Personalized therapy
Published Date	2022-02-07
Publication Title	Respiratory Research
Volume	volume23
Issue	issue1
Publisher	BMC
Start Page	20
ISSN	1465-993X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2022.
File Version	publisher
PubMed ID	35130915
DOI	10.1186/s12931-022-01940-y
Web of Science KeyUT	000752386100002
Related Url	isVersionOf https://doi.org/10.1186/s12931-022-01940-y

Nodal Peripheral T-cell Lymphoma with T Follicular Helper Phenotype Presenting as Chorea During Treatment: A Case Report and Literature Review

FullText URL	fulltext.pdf
Author	Kitamura, Wataru\| Ennishi, Daisuke\| Yukawa, Ryoya\| Sasaki, Ryo\| Yoshida, Chikamasa\| Takasuka, Hiroki\| Fujiwara, Hideaki\| Asada, Noboru\| Nishimori, Hisakazu\| Fujii, Keiko\| Fujii, Nobuharu\| Matsuoka, Ken-Ichi\| Abe, Koji\| Yoshino, Tadashi\| Maeda, Yoshinobu\|
Keywords	peripheral T-cell lymphoma chorea single photon-emission computed tomography
Published Date	2021-10-01
Publication Title	Internal Medicine
Volume	volume60
Issue	issue19
Publisher	The Japanese Society of Internal Medicine
Start Page	3155
End Page	3160
ISSN	0918-2918
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	33814503
DOI	10.2169/internalmedicine.7180-21
Web of Science KeyUT	000706487700015
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.7180-21

Dramatic Response to Carboplatin Plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis

FullText URL	fulltext.pdf
Author	Oda, Naohiro\| Tabata, Masahiro\| Uno, Masatoshi\| Umeda, Yuzo\| Kato, Hironari\| Kubo, Toshio\| Senoo, Satoru\| Yagi, Takahito\| Fujiwara, Toshiyoshi\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	pancreas mucinous cystadenocarcinoma carboplatin paclitaxel
Published Date	2021-09-15
Publication Title	Internal Medicine
Volume	volume60
Issue	issue18
Publisher	The Japanese Society of Internal Medicine
Start Page	2967
End Page	2971
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	33814494
DOI	10.2169/internalmedicine.6730-20
Web of Science KeyUT	000697279400013
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6730-20

Marginal Zone Lymphoma and Lung Adenocarcinoma with an EGFR Exon 19 E746-S752del Mutation in a Patient with IgG4-related Disease

FullText URL	fulltext.pdf
Author	Okawa, Sachi\| Rai, Kammei\| Fujii, Nobuharu\| Gion, Yuka\| Ninomiya, Kiichiro\| Kato, Yuka\| Taniguchi, Akihiko\| Kubo, Toshio\| Ichihara, Eiki\| Ohashi, Kadoaki\| Miyahara, Nobuaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	EGFR IgG4-related disease marginal zone lymphoma osimertinib
Published Date	2021-09-01
Publication Title	Internal Medicine
Volume	volume60
Issue	issue17
Publisher	The Japanese Society of Internal Medicine
Start Page	2831
End Page	2837
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	33775999
DOI	10.2169/internalmedicine.6470-20
Web of Science KeyUT	000695856000020
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.6470-20

Triple therapy with osimertinib, bevacizumab and cetuximab in EGFR‑mutant lung cancer with HIF‑1α/TGF‑α expression

FullText URL	fulltext20210810-3.pdf
Author	Nishii, Kazuya\| Ohashi, Kadoaki\| Watanabe, Hiromi\| Makimoto, Go\| Nakasuka, Takamasa\| Higo, Hisao\| Ninomiya, Kiichiro\| Kato, Yuka\| Kubo, Toshio\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	epidermal growth factor receptor osimertinib bevacizumab cetuximab hypoxia‑inducible factor‑1α transforming growth factor‑α
Published Date	2021-7-7
Publication Title	Oncology Letters
Volume	volume22
Issue	issue3
Publisher	Spandidos Publications
Start Page	639
ISSN	1792-1074
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Nishii et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
File Version	publisher
DOI	10.3892/ol.2021.12900
Web of Science KeyUT	000678494600001
Related Url	isVersionOf https://doi.org/10.3892/ol.2021.12900

Sarcopenia is associated with poor prognosis after chemoradiotherapy in patients with stage III non-small-cell lung cancer: a retrospective analysis

FullText URL	fulltext.pdf
Author	Katsui, Kuniaki\| Ogata, Takeshi\| Sugiyama, Soichi\| Yoshio, Kotaro\| Kuroda, Masahiro\| Hiraki, Takao\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kanazawa, Susumu\|
Published Date	2021-06-04
Publication Title	scientific reports
Volume	volume11
Issue	issue1
Publisher	Nature Research
Start Page	11882
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	34088965
DOI	10.1038/s41598-021-91449-z
Web of Science KeyUT	000678611200010
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-91449-z

Reduced dose of PTCy followed by adjuvant alpha-galactosylceramide enhances GVL effect without sacrificing GVHD suppression

FullText URL	fulltext.pdf
Author	Nakamura, Makoto\| Meguri, Yusuke\| Ikegawa, Shuntaro\| Kondo, Takumi\| Sumii, Yuichi\| Fukumi, Takuya\| Iwamoto, Miki\| Sando, Yasuhisa\| Sugiura, Hiroyuki\| Asada, Noboru\| Ennishi, Daisuke\| Tomida, Shuta\| Fukuda-Kawaguchi, Emi\| Ishii, Yasuyuki\| Maeda, Yoshinobu\| Matsuoka, Ken-Ichi\|
Published Date	2021-06-23
Publication Title	Scientific Reports
Volume	volume11
Issue	issue1
Publisher	Nature Research
Start Page	13125
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021
File Version	publisher
PubMed ID	34162921
DOI	10.1038/s41598-021-92526-z
Web of Science KeyUT	000669995600012
Related Url	isVersionOf https://doi.org/10.1038/s41598-021-92526-z

Unusual oral mucosal microbiota after hematopoietic cell transplantation with glycopeptide antibiotics: potential association with pathophysiology of oral mucositis

FullText URL	fulltext20210601-2.pdf
Author	Muro, Misato\| Soga, Yoshihiko\| Higuchi, Tomoko\| Kataoka, Kota\| Ekuni, Daisuke\| Maeda, Yoshinobu\| Morita, Manabu\|
Keywords	hematopoietic stem cell transplantation oral mucositis microbiota antibiotics PCR-denaturing gradient gel electrophoresis
Note	This is a post-peer-review, pre-copyedit version of an article published in Folia Microbiologica. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12223-018-0596-1.\|
Published Date	2018-03-12
Publication Title	Folia Microbiologica
Volume	volume63
Issue	issue5
Publisher	Springer Science and Business Media LLC
Start Page	587
End Page	597
ISSN	0015-5632
NCID	AA00648779
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	29532421
NAID	120007042396
DOI	10.1007/s12223-018-0596-1
Web of Science KeyUT	000440115900006
Related Url	isVersionOf https://doi.org/10.1007/s12223-018-0596-1

Successful Treatment of Acute Promyelocytic Leukemia Complicated with Endometrial Cancer by Arsenic Trioxide

JaLCDOI	10.18926/AMO/61904
FullText URL	75_2_219.pdf
Author	Sugiura, Hiroyuki\| Nishimori, Hisakazu\| Matsuoka, Hirofumi\| Nakamura, Keiichiro\| Fujii, Keiko\| Fujii, Nobuharu \| Matsuoka, Ken-ichi \| Maeda, Yoshinobu\|
Abstract	Acute promyelocytic leukemia (APL) is a hematological emergency that requires urgent intervention because of the high incidence of early hemorrhagic death. When patients with APL experience a synchronous solid organ tumor, the tumor’s treatment must also be done properly. Differentiation-inducing therapy using arsenic trioxide (ATO) has less hematological toxicity compared to cytotoxic chemotherapy and might be preferable for untreated APL patients with a synchronous solid organ tumor. Here we describe the first successful case of untreated APL and synchronous endometrial cancer (in an adult Japanese woman) treated with ATO consolidation therapy and the subsequent surgery and chemotherapy for endometrial cancer.
Keywords	acute promyelocytic leukemia endometrial cancer arsenic trioxide synchronous multiple primary malignant tumor chemotherapy
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2021-04
Volume	volume75
Issue	issue2
Publisher	Okayama University Medical School
Start Page	219
End Page	224
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2021 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33953429
NAID	120007029883

VEGFR2 blockade augments the effects of tyrosine kinase inhibitors by inhibiting angiogenesis and oncogenic signaling in oncogene-driven non-small-cell lung cancers

FullText URL	fulltext.pdf
Author	Watanabe, Hiromi\| Ichihara, Eiki\| Kayatani, Hiroe\| Makimoto, Go\| Ninomiya, Kiichiro\| Nishii, Kazuya\| Higo, Hisao\| Ando, Chihiro\| Okawa, Sachi\| Nakasuka, Takamasa\| Kano, Hirohisa\| Hara, Naofumi\| Hirabae, Atsuko\| Kato, Yuka\| Ninomiya, Takashi\| Kubo, Toshio\| Rai, Kammei\| Ohashi, Kadoaki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Published Date	2021-01-07
Publication Title	Cancer science
Publisher	Wiley
ISSN	1347-9032
NCID	AA11808050
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
PubMed ID	33410241
NAID	120007008532
DOI	10.1111/cas.14801
Web of Science KeyUT	000630136900001
Related Url	isVersionOf https://doi.org/10.1111/cas.14801

Lung stereotactic body radiation therapy for elderly patients aged >= 80 years with pathologically proven early-stage non-small cell lung cancer: a retrospective cohort study

FullText URL	fulltext.pdf
Author	Watanabe, Kenta\| Katsui, Kuniaki\| Sugiyama, Soichiro\| Yoshio, Kotaro\| Kuroda, Masahiro\| Hiraki, Takao\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kanazawa, Susumu\|
Keywords	Clinical pathology Elderly Non-small cell lung carcinoma Radiosurgery Stereotactic body radiation therapy
Published Date	2021-02-23
Publication Title	Radiation Oncology
Volume	volume16
Issue	issue1
Publisher	BMC
Start Page	39
ISSN	1748-717X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2021.
File Version	publisher
PubMed ID	33622369
DOI	10.1186/s13014-021-01769-7
Web of Science KeyUT	000623175000001
Related Url	isVersionOf https://doi.org/10.1186/s13014-021-01769-7

Volumetric PET Parameters Predict Prognosis after Definitive Chemoradiotherapy with Cisplatin/Docetaxel for Stage III Non-Small Cell Lung Cancer

JaLCDOI	10.18926/AMO/61429
FullText URL	75_1_15.pdf
Author	Katsui, Kuniaki\| Ogata, Takeshi\| Tada, Akihiro\| Sugiyama, Soichi\| Yoshio, Kotaro\| Kuroda, Masahiro\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Hiraki, Takao\| Kanazawa, Susumu\|
Abstract	The aim of this study was to investigate whether volumetric positron emission tomography (PET) parameters are prognostic predictors in stage III non-small cell lung cancer patients receiving definitive concurrent chemo-radiotherapy (CCRT) with cisplatin/docetaxel. Cases involving definitive CCRT were reviewed retrospectively, and the maximum standardized uptake value, metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were calculated. The relationships between these PET parameters and prognosis were analyzed. MTV and TLG were significant predictors of distant metastasis-free survival (DMFS) (p = 0.0003 and 0.0005, respectively) and progression-free survival (PFS) (p = 0.001 and 0.0007, respectively). The three-year DMFS rates in patients with low and high MTV were 13.3% and 64.6%, respectively, and the corresponding values in those with low and high TLG were 13.3% and 65.2%, respectively. The three-year PFS rates in patients with low and high MTV were 13.3% and 57.8%, respectively, and the corresponding values in patients with low and high TLG were 13.3% and 57.8%, respectively. However, MTV and TLG were not predictors of local control or overall sur-vival. We demonstrated that volumetric PET parameters were predictors of patients receiving definitive CCRT. Our findings contradict the findings of previous reports and warrant further research to validate them.
Keywords	volumetric positron emission tomography parameters distant metastasis-free survival chemoradiotherapy cisplatin/docetaxel non-small cell lung cancer
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2021-02
Volume	volume75
Issue	issue1
Publisher	Okayama University Medical School
Start Page	15
End Page	23
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2021 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33649609