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JaLCDOI 10.18926/40189
タイトル(別表記) Medical studies on the rural people (3). Incidence rate of hypertension in rural districts, Tottori Prefecture, Japan
フルテキストURL pitsr_037_037_042.pdf
著者 井上 正勝| 森永 寛|
抄録 The authors examined the blood pressure levels of 5, 358 out-patients of Branch Hospital of Okayama University Hospital, Tottori Prefecture, during the four-year period, from April, 1957 to March, 1961. The following results were obtained: I. The incidence of hypertension with a systolic blood pressure over 150 mmHg was 20.5% (1,093 cases of 5,358). 2. Patients with hypertension over 40 years of age was 35.9% in male and 41.5% in female. Females showed a higher incidence than males and the incidence rate of hypertension increased with age. 3. There was a tendency in the incidence rate of patients with hypertension decreased in summer and increased in cold seasons.
出版物タイトル 岡山大学温泉研究所報告
発行日 1967-12-15
37巻
開始ページ 37
終了ページ 42
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002400930
JaLCDOI 10.18926/40188
タイトル(別表記) The isotopic ratio (234)U/(238)U of the ores and waters in Togo Mine, Tottori-ken, Japan
フルテキストURL pitsr_037_031_036.pdf
著者 梅本 春次|
抄録 The ratio (234)U/(238)U of two groups of ores and the waters collected in Kannokura Deposit was determined by α-ray spectrometry. According to the geological and mineralogical observation, the ores of each group were formed in succession. Based on the assumption that (234)U/(238)U of the uranium in the leaching solution is higher than that in the ores, the obtained ratio supports the above mechanism of formation. Actually, the waters collected in Kannokura Deposit showed the fairly high value in (234)U/(238)U. Each stratum of a typical section of the mine was observed on the ratio, but the obtained values were in too much complicated relation to interpret.
出版物タイトル 岡山大学温泉研究所報告
発行日 1967-12-15
37巻
開始ページ 31
終了ページ 36
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002400929
JaLCDOI 10.18926/40187
タイトル(別表記) The positive rate of RA- test in various diseases, with supplementary study on the RA-test of synovial fluid
フルテキストURL pitsr_037_021_030.pdf
著者 江沢 英光|
抄録 Since the report of the agglutination test with Streptococcus by Cecil in 1931 there appeared many reports dealing with the serum reaction involved in rheumatoid arthritis. Among these the modified form of sensitized sheep blood cell agglutination test as proposed by WAALER (1940) and ROSE (1948) had been for a long time the only method applied to the diagnosis of rheumatoid arthritis. However, as this method had disadvantages of its complex manipulation and of being relatively sensitive, generally satisfactory results could not be obtained with it. Since then the latex agglutination test by PLATZ and SINGER (1957) was used in conjuction with the bentonite agglutination test by BOZIEVICH (1957). By the RA-test it means the test where agglutination is attained by the combined reaction of the human serum to be tested and the polystyrene latex granules bound to human gamma-globulin, and it is being widely used in daily clinical examinations. For the purpose to know the positive rate of this test in disesaes other than rheumatoid arthritis, we applied this test to the patients with various diseases both visiting our out-patient clinic and those hospitalized, and studied the results.
出版物タイトル 岡山大学温泉研究所報告
発行日 1967-12-15
37巻
開始ページ 21
終了ページ 30
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002400928
JaLCDOI 10.18926/40186
タイトル(別表記) Our experience in combined balneo- and chrysotherapy for rheumatoid arthritis
フルテキストURL pitsr_037_009_019.pdf
著者 江沢 英光|
抄録 There was a time when the adrenocortical hormones therapy was only available treatment for rheumatoid arthritis, but since it does not give lasting effect on chronic rheumatoid arthritis, opinions are varied as to its efficacy, so that at present we are still conducting studies about this problem. Ever since the reports on the gold therapy for rheumatoid arthritis of LANDE (1927) and FORESTIER (1929) the literature is replete with the results of gold therapy both in Europe and America. In Japan, however, it was with reports by OSHIMA (1957) and HASHIMOTO(1961) that first aroused the interest of general investigators in this gold therapy. Nevertheless, since we find no convincing methods of treatment, we attempted to give combined balneo- and chryotherapys therapy to the pateints coming to the Department of Internal Medicine of Misasa (Hot-springs) Hospital, which is located in Tottori Prefecture and is a Branch of Okayama University Hospital, over the period of the past five years, and studied the efficacy of such treatment. Our subjects were consisted of 93 cases of rheumatoid arthritis with duration of 4.8 years in average. For the balneotherapy the patients were made to rest for the first the bathing week, the combined with mud treatment and massage once or twice a day was given in the second week, and then the gold therapy was commenced. Gold thioglucose oil emulsion (Solganal B. product of Schering) was used. In the first week, 5-10 mg of Solganal B were given twice. 10 mg were given twice in the second week, and thereafter the doses were gradually increased until the total dosage reached 1.0~1.5g. By the combined balneo- and chrysotherapy applied to the 93 cases of rheumatoid arthritis, we obtained the results as follows. 1. The improvement in the erythrocyte sedimentation rate was observed in 77% of them. 2. The improvement in the CRP test was observed in 46%, but the aggravation was found in 8.7% of their conditions. 3. There were 53 cases (57%) whose RA-test was either weakened or turned negative. 4. Judging from the changes in the erythrocyte sedimentation rate and the doses of gold thioglucose given, the effects of such a treatment appear around the tenth week after the start of the treatment and it seems that the total dosage of 500 mg and over gold salt is most appropriate. 5. By the combined treatment there were 10 (48%) of 21 cases whose conditions had improved well enough as to withdraw corticosteroids treatment and remaining 11 cases (52%) who had improved to the extent where we could reduce the amount of corticosteroids. 6. By applying the evaluating system of HASHIMOTO, the efficacy rate of the treatment proves to be 89% in the cases given over 500 mg gold thioglucose, and out of these 49% showed a marked effect. Therefore, it seems that the optimal dosage is over 500 mg. 7. These results amply indicate that for the treatment of chronic rheumatoid arthritis the balneotherapy combined with some organic gold compound or salt (Solganal B in the present study) is highly beneficial.
出版物タイトル 岡山大学温泉研究所報告
発行日 1967-12-15
37巻
開始ページ 9
終了ページ 19
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002400927
著者 岡山大学温泉研究所|
発行日 1967-12-15
出版物タイトル 岡山大学温泉研究所報告
37巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1967-12-15
出版物タイトル 岡山大学温泉研究所報告
37巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1969-03-20
出版物タイトル 岡山大学温泉研究所報告
38巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1969-03-20
出版物タイトル 岡山大学温泉研究所報告
38巻
資料タイプ その他
JaLCDOI 10.18926/40181
タイトル(別表記) The determination of serum triglycerides
フルテキストURL pitsr_038_077_084.pdf
著者 御船 政明|
抄録 Currently accepted methods for serum triglycerides, namely, the manual modified VAN HANDEL-KAWADE method and the semi-automated LOFLAND method, were critically examined. Since the absorbents, the quality of sulfuric acid, the processes of shaking, extraction, saponification, removal of ethanol after saponification, and the stability of colored solution appear to be essential factors governing precision and accuracy of the determination, the effects of these factors were studied. It was found that the process of removal of ethanol was most important. To obtain the reproducible absorption, it is most advantageous to evaporate off ethanol from the solution of pH⋍6 on an oil bath at 101℃. As a result of re-examination on LOFLAND'S semi-automated method using a standard AutoAnalyzer, it is shown that the mixing coils can be omitted, thereby making the analysis possible in 18 -19 minutes (In the original LOFLAND'S method it takes more than 22 minutes). In addition, this modification results in smaller amount of chromotropoc acid reagent necessary (2.9 ml/min. as compared to 5 ml/min. in the original method). The determination rate in this modified method is 25 samples per hour. The average values, standard deviations, and coefficients of variance for the same serum sample for ten analyses according to the suggested manual method were 55.0 mg/dl, 1.83 mg/dl, and 4.69%, respectively, and those according to the suggested semi-automated method were 53.6 mg/dl, 1.78mg/dl and 4.68%, respectively.
出版物タイトル 岡山大学温泉研究所報告
発行日 1969-03-20
38巻
開始ページ 77
終了ページ 84
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398501
JaLCDOI 10.18926/40180
タイトル(別表記) Medical studies on the rural people (4). Survey of health among farm community residents
フルテキストURL pitsr_038_045_075.pdf
著者 的場 邦和|
出版物タイトル 岡山大学温泉研究所報告
発行日 1969-03-20
38巻
開始ページ 45
終了ページ 75
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398500
JaLCDOI 10.18926/40179
タイトル(別表記) Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part 3. The effects of balneotherapeutical procedures on blood pH, P(CO(2)) and P(O(2))
フルテキストURL 038_027_044.pdf
著者 八幡 隆昭|
抄録 The effects of balneological procedures as well as the duration of hospitalization on blood pH, P(CO(2)) and P(O(2)) were studied in fifty-two patients chiefly including rheumatoid arthritics. The changes of these parameters in sixty minutes after any foment were discussed comparing with those in the control groups. The results were as follows. 1) Blood pH decreased in value from first to second hospital week and thereafter remained almost constant. No P(CO(2)) variation was observed. The P(O(2)) remained stable till third hospital week and then followed by up and down changes during the forth to the ninth week. 2) The arterial blood pH, P(CO(2)) and P(O(2)) in all showed a tendency to increase after the general spring bath of ten minutes duration (bath temp. : 40±1℃). The venous blood pH and P(O(2)) also increased as in the arterial but P(CO(2)) decreased. These non significcant changes in the venous blood were considered to be resulted from the increased cutaneous blood flow in the forearm. 3) It was showed that mud bath of twenty minutes duration (bath temp. : 40±1℃) made an influence on the venous blood pH, P(CO(2)) and P(O(2)) via two different mechanisms. The first is the increased blood flow which had five minute value of P(O(2)) and pH elevated but P(CO(2)) reduced significantly. The second is the prominent increase of oxygen uptake in which the significant reduction of five minute P(O(2)) value but no variation of pH or P(CO(2)) was demonstrated. It was suggested that these two types of variations were based on the difference of individual response to heat. 4) The signiilcant blood pH, P(CO(2)) and P(O(2)) changes after mud pack of twenty minutes duration (surface temp. : 40~50℃) were considered to reflect the increased blood flow. 5) The increased cutaneous blood flow induced by balneotherapeutical procedures was proved to remain as long as sixty minutes thereafter in almost all cases. 6) The blood pH, P(CO(2)) and P(O(2)) changes observed in the control groups were related mainly with the increased blood flow and only little, if any, with the elevated oxygen uptake.
出版物タイトル 岡山大学温泉研究所報告
発行日 1969-03-20
38巻
開始ページ 27
終了ページ 44
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532344
JaLCDOI 10.18926/40178
タイトル(別表記) Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part 2. Relationships between the physiopathological factors and blood pH, P(CO(2)) and P(O(2))
フルテキストURL 038_011_025.pdf
著者 八幡 隆昭|
抄録 From the factors which are considered to make an effect on circulatory or metabolic states, hemoglobin content, erythrocyte sedimentation rate, room temperature, respiratory rate and pulse rate were chosen to be discussed their relationships between the pH, P(CO(2)) and P(O(2)). Moreover, changes due to age and disease as well as diurnal and seasonal variations of blood pH, P(CO(2) and P(O(2)) were evaluated. 1) Blood pH and Peo2 showed the tendency of reduction in the order of 40~59, 10~39 and 60~79 years age group in the former and in the latter 40~59, 60~79 and 10~39 years age group. The P(O(2)) value in the afternoon decreased with ageing. However, no significance was demonstrated in any age group. 2) Diurnal changes of pH in 10~59 age group was very small. In the 60~79 age group, the afternoon value decreased than the morning one. The P(O(2)) value in the 10~59 age group increased in the afternoon contrasted to the decreasement in the 60~79 age group. The P(CO(2)) variations in all age groups were within the errors due to the measurement. 3) Rheumatiod arthritics group showed no significant diurnal variation different from non-rheumatoid arthritics group. 4) Blood pH of December-February group showed the lowest seasonal value and significant difference between March - May and September - November group. No significant seasonal variation was observed in the blood P(CO(2)) and P(O(2)). 5) The central nervous system group showed the significant lower blood pH than cardiovascular disease and rheumatoid arthritis group. The P(CO(2)) values of rheumatoid arthritis group were lower significantly than cardiovascular disease, central nervous system, and musculo- keletal system patient groups. None of diseases showed significant P02 difference each other. 6) Significant relationship was demonstrated between erythrocyte sedimentation rate and P(O(2)) value only in cardiovascular disease patient group. 7) There were the significant relationships between room temperature and P(O(2)) in rheumatoid arthritis and metabolic disease groups. 8) Significant relationships were shown between respiratory rate and pH in rheumatoid arthritis and cardiovascular disease groups. 9) There was significant relationship between pulse rate and pH only in rheumatoid arthritis groups. 10) The combination of the blood pH, P(CO(2)) and P(O(2)), values was shown to reflect the circuratory or metabolic states of the tissues or organs and to remain stable on the experimental day.
出版物タイトル 岡山大学温泉研究所報告
発行日 1969-03-20
38巻
開始ページ 11
終了ページ 25
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532343
JaLCDOI 10.18926/40177
タイトル(別表記) Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part I. Evaluation of measurement apparatus and methods of the proccedures
フルテキストURL pitsr_038_001_009.pdf
著者 八幡 隆昭|
抄録 Human venous blood pH, P(CO(2)) and P(O(2)) were measured with I. L. Meter. Its reproducibility and response rate were evaluated as well as methods of the procedures. 1) Time required to reach the stability of pH, P(CO(2)), and P(O(2)) reading after the sampie injection was 1~1.5 min., 2~2.5 min. and 45~75 sec., respectively. It is recommended in the measurement of these parameters at the same time that the sample injection starts with P(CO(2)) electrode, followed by pH and P(O(2)) in this order and that readings are recorded in the order of pH, P(O(2)) and P(CO(2)). 2) Range of differences between the two values measured in the interval of 3~5 min. were pH : -0.010~0.020 (mean: 0.003), P(CO(2)) : -1.0~1.0mmHg (mean: 0.4) and P(O(2)) : -1.0~0.0mmHg (mean: -0.5). Their 5% rejection limits were 0.021≧x(o)≧-0.015, 2.0≧x(o)≧-1.2mmHg and 0.3≧x(o)≧-1.3mmHg, respectively. 3) The pH, P(CO(2)) and P(O(2)) of the heparinized venous blood stored in ice water showed no significant changes in 60 min. and they gave practically the same results as the measurement just after shedding.
出版物タイトル 岡山大学温泉研究所報告
発行日 1969-03-20
38巻
開始ページ 1
終了ページ 9
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398499
著者 岡山大学温泉研究所|
発行日 1969-03-20
出版物タイトル 岡山大学温泉研究所報告
38巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1970-03-30
出版物タイトル 岡山大学温泉研究所報告
39巻
資料タイプ その他
著者 岡山大学温泉研究所|
発行日 1970-03-30
出版物タイトル 岡山大学温泉研究所報告
39巻
資料タイプ その他
JaLCDOI 10.18926/40173
タイトル(別表記) Follow-up results of rheumatic disorders treated with hot springs
フルテキストURL pitsr_039_077_080.pdf
著者 松本 欣之|
抄録 Misasa Spa, located in Tottori Prefecture, was discovered in 1164, and it has been widely used for the management of rheumatic disorders, gastrointestinal diseases and so on. In 1914, Dr. R. ISHIZU measured radon contents in Misasa spring waters to be 142.14 Mache, and then Misasa Hot Springs, alkaline common salt springs, were also known as radioactive hot springs. In July, 1958, patients with rheumatic complaints who had balneotherapy at Misasa Branch Hospital of Okayama University, from January, 1955 to March, 1958, were reexamined. A questionnaire about the effectiveness of balneotherapy was sent to 149 patients and 98 answers were received. The results were as follows: 1. Spa treatment was effective in 100% of shoulder-hand syndrome and osteo-arthrosis of the knee, in 95% of degenerative spondylosis, in 93% of rheumatoid arthritis, in 80% of low back pain, in 67% of sciatica, etc. Generally speaking, balneotherapy was effectual in 78 of 98 patients with rheumatic disorders (81.2%). 2. The effectiveness of spa treatment came out in the course of thermal cure in 74% of 78 cases, and the others recognized the effects after spa treatment was finished. 3. The effect of spa therapy on the subjective complaints was notable in the cases which had a period of spa treatment over half a month. In the cases which had a period of spa treatment within 2 weeks, it is thought that the period is too short to reveal the efficacy of hot spring bathing. 4. It appeared that drinking of hot spring water had no remarkable effect on rheumatic complaints. 5. Forty-three per cent of the cases answered that their body conditions during this inquiry time became better than that at the beginning of the balneotherapy, and the remainders of the reexamined cases were under the trcatments with cortisone, vitamine, massage, acupuncture and so forth.
出版物タイトル 岡山大学温泉研究所報告
発行日 1970-03-30
39巻
開始ページ 77
終了ページ 80
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002398498
JaLCDOI 10.18926/40172
タイトル(別表記) The effect of radioaclive thermal bathing upon serum iron values
フルテキストURL 039_061_075.pdf
著者 山本 泰久|
抄録 The author investigated the effect of radioactive hot spring bathing on serum iron values. The serum iron values were measured by Umemoto-Yamamoto's method using o-nitrosoresorcin monomethylether, as a colour-developing reagent. The chemical compositions of the spring water used is as following: pH : 7.04, Rn : 38-151x10(-10)curies/l, K(+) : 14.0, Na(+) : 540.2, Ca(++) : 61. 2, Mg(++) : 6.6, Fe(++) : 89.0, AI(+++) : 0.1, Cl(-) : 709.5, S0(4)(--) : 179.5, HCO(3)(-) : 226.7, H(2)SiO(3) : 89.0, HBO(2) : +, CO(2) : 29.5, totaling 1,827mg/kg. 1) Single bathing: The iron values in the serum were measured before and after 0, 1/2, 1 and 2 hours after the radioactive thermal bathing for 10 minutes in water of 41 ±2℃ in temperature. Single thermal bathing showed no significant effect on the serum iron values in healthy hnman subjects, but the serum iron concent:'ations in healthy white rabbits tended to decrease following single thermal bathing and to remain at a decreased level for 1/2 to 1 hour, and returned to normally within 2 hours from the time of the bathing (Table 1, 2 and Fig. 1, 2). 2) A series of baths: The author examined the serum iron values of patients with rheumatic disorders before and 3rd, 7th, 14th, 21st and 28th days after in the course of "a series of baths" in radioactive hot spring. Patients bathed in water of 41 ± 2℃ in temperature, for 5-10 minutes, 2 or 3 times daily. A fall in the serum iron values was seen on the 3rd to 7th days. At that time the pattern of iron absorption from intestine showed a iron dificiency anemia type. The rate of absorption of iron was rapid. At about the 14th day, the serum iron values of patients tended to increase but unbound iron-binding capacity of the serum decreased. Subsequently, the serum iron values returned to the initial levels between the 21st and 28th day (Table 3, 4, 5, and Fig. 3, 4, 5), 3) It is said that the reticulo-endothelial system plays an inportant part in iron metabolism. The author injected 5 ml of Indian ink into the aural vein of rabbits for the purpose of blocking the reticulo-endothelial system. These procedures were carried out once a day for 7 successive days. The rabbits with "a blockade of R. E. S." had no significant change in the serum iron values during a series of baths. From what has been stated in the above, it may be said that bathing in radioactive hot springs regubtes the iron metabolism of patients with anemia and brings about the acceleration of the medullary function.
出版物タイトル 岡山大学温泉研究所報告
発行日 1970-03-30
39巻
開始ページ 61
終了ページ 75
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 40017532352
著者 井上 妙子| 池上 忠興| 森永 寛|
発行日 1970-03-30
出版物タイトル 岡山大学温泉研究所報告
39巻
資料タイプ データ・データベース
JaLCDOI 10.18926/40170
タイトル(別表記) Study on the conbined therapy of spa and gold salt in rheumatoid arthritis Part II. An experience of granulocytopenia possibly caused by gold salt preparation
フルテキストURL pitsr_039_037_042.pdf
著者 池上 忠興| 八幡 隆昭| 北山 稔| 森永 寛|
抄録 A thirty seven years old woman with rheumatoid arthritis was instituted gold salt intramuscularly twice a week on the nineteenth hospital day. On the fifty fourth day, however, it was discontinued at the total dosis of 180 mg because of the skin rush. In about ten days after stopping gold injection appeared high fever with shivering and granulocytopenia was demonstrated. With immediate administration of ACTH, adrenocortical hormons etc. including blood transfusion the abnormal findings of the blood pictures returned to normal and the patient became well. Recently, gold salts are so widely used in treatment of rheumatoid arthritis as one of specific antirheumatic agents that the possible severe side effect such as granulocytopenia, if quite rare, should always be considered in the course of gold therapy.
出版物タイトル 岡山大学温泉研究所報告
発行日 1970-03-30
39巻
開始ページ 13
終了ページ 35
ISSN 0369-7142
言語 日本語
論文のバージョン publisher