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著者 西丸 和義|
発行日 1928-08-31
出版物タイトル 岡山医学会雑誌
巻 40巻
号 8号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/47028
フルテキストURL mfe_36_2_073_082.pdf
著者 Hidayat, Iip Syarif| Toyota, Yoshitaka| Torigoe, Osamu| Wada, Osami| Koga, Ryuji|
抄録 A multi-path ring-resonator (MPRR) was proposed to extend FSR of ring resonator. However, it is complicated to analyze the MPRR by using well-known analysis techniques such as scattering matrix or other numerical methods. This paper describes procedure for deriving transfer matrix by means of signal flow-chart to analyze the MPRR. We do not need complicated calculation for steady state analysis because transfer matrix elements are formulated clearly. As a result, The calcultaion time in this method can be reduced 1/3 to 1/20 times compared with using scattering matirx method. Furthermore, a transmittance characteristics of the MPRR at FSR extension-factor of 10 will also be shown. This suggests that analysis of other types of the MPRR by using this method can be performed simply and take a shorter time.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2002-03
巻 36巻
号 2号
開始ページ 73
終了ページ 82
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497050
JaLCDOI 10.18926/47025
フルテキストURL mfe_36_2_051_060.pdf
著者 Hikida, Masaki| Magari, Masaki| Nakayama, Yasunori| Kanayama, Naoki| Ohmori, Hitoshi|
抄録 A population of peripheral B cells have been shown to express recombination activating gene products, RAG-1 and RAG-2, which are considered to be involved in revising the B cell antigen receptor (BCR) in the periphery. BCR engagement has been reported to turn off RAG expression in peripheral B cells, whereas the same treatment has an opposite effect in immature B cells in the bone marrow. In contrast to receptor editing that is involved in the removal of autoreactivity in immature B cells, it has been shown that secondary V(D)J rearrangement in peripheral B cells, termed receptor revision, contributes to affinity maturation of antibodies. Here, we show that RAG-2 expression in murine splenic B cells was abrogated by the coligation of BCR with complement receptors (CD21/CD35) much more efficiently than by the engagement of BCR alone. On the other hand, the same coligation augmented proliferation of anti-CD40-stimulated B cells. Consistent with these observations, RAG-2 expression was lower in the draining lymph nodes of the quasi-monoclonal mice when they were immunized with a high-affinity antigen than with a low-affinity one. These findings suggest a crucial role for CD21/CD35 in directing the conservation or the revision of BCRs in peripheral B cells.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2002-03
巻 36巻
号 2号
開始ページ 51
終了ページ 60
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80015582223
JaLCDOI 10.18926/47021
フルテキストURL mfe_36_2_001_006.pdf
著者 Sakakibara, Akira| Kanadani, Teruto| Tashiro, Tsutomu| Yoshioka, Kazumi|
抄録 The effect of heat-treatment conditions on occurrence of serration in Al-Zn alloys was investigated. Specimens were aged for various times up to 2.6Ms at 293K or 273K after quenching from various temperatures (T(Q)), 473K to 853K, and tensile-tested at room temperature. Serration occurred more easily according as T(Q) became lower and the aging time became shorter: in the case that T(Q)=473K serration was observed even after aging for 2.6Ms, while in the case that T(Q)=773K serration did not occur irrespective of aging conditions. Serration was also recognized when the specimens were furnace-cooled from 773K to room temperature. These results together with those obtained by the electrical resistometry suggest that the serration in the low'concentrated Al-Zn alloy is caused by the formation of small GP zones whose Guinier radius is less than 1nm or some sort of solute clusters.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2002-03
巻 36巻
号 2号
開始ページ 1
終了ページ 6
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80015497758
著者 Nogami, Naoyuki| Hotta, Katsuyuki| Kuyama, Shoichi| Kiura, Katsuyuki| Takigawa, Nagio| Chikamori, Kenichi| Shibayama, Takuo| Kishino, Daizo| Hosokawa, Shinobu| Tamaoki, Akihiko| Harita, Shingo| Tabata, Masahiro| Ueoka, Hiroshi| Shinkai, Tetsu| Tanimoto, Mitsune|
発行日 2011-10
出版物タイトル Lung Cancer
巻 74巻
号 1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/47018
フルテキストURL 65_5_347.pdf
著者 Mukai, Takashi| Mimura, Hidefumi| Gobara, Hideo| Shimizu, Mitsuharu| Niiya, Harutaka| Kanazawa, Susumu|
抄録 We report herein the case of a 76-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) and chronic renal failure resulting in intractable abdominal distension and anorexia. Computed tomography (CT) showed enlarged and cystic kidneys. We performed transcatheter arterial embolization (TAE) for renal arteries with ethanol. Absolute ethanol with iodinated contrast medium or Lipiodol was delivered into both renal arteries. The patient's low-grade fever subsided in 5 days, and no other complication occurred. The sensation of abdominal distension diminished approximately 1 month after embolization. A progressive decrease in kidney size was observed soon after embolization. The percentage of the decrement of kidney size was approximately 50% after 17 months. These results indicate that renal TAE with ethanol is a safe, cost-effective, and minimally invasive technique to reduce kidney size in symptomatic ADPKD patients.
キーワード autosomal dominant polycystic kidney disease transcatheter arterial embolization ethanol
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2011-10
巻 65巻
号 5号
出版者 Okayama University Medical School
開始ページ 347
終了ページ 351
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037273
Web of Science KeyUT 000296116400010
JaLCDOI 10.18926/AMO/47014
フルテキストURL 65_5_325.pdf
著者 Hu, Hai| Zhu, Jiang Fan| Huang, An Hua| Xin, Ying| Xu, An An| Chen, Bingguan|
抄録 To further improve our developed transumbilical endoscopic surgery (TUES), we developed a completely covert laparoscopic cholecystectomy (LC). Twelve cases of LC were recruited for this new approach. First, a 10-mm trocar was placed above the umbilicus for inserting the laparoscope. Two 5-mm trocars were then placed near the right and left ends of the superior margin of the suprapubic hair. After the 5-mm 30° laparoscope was shifted to the left suprapubic trocar, the harmonic scalper, electric hook, and grasper were inserted either through the 10-mm umbilical trocar or through the right suprapubic trocar. All gallbladders were successfully removed without intraoperative complications. The mean operating time was 28.5±5.7min (range 20-45min). All patients felt well after surgery and did not need postoperative analgesia. They resumed free oral intake 6h after the procedure. All patients were satisfied with the appearance of the incisions, which were completely hidden in the umbilicus and suprapubic hair. The approach we developed has overcome both external instrument interference around the umbilicus and the loss of triangulation in the operative field. It is relatively simpler than a typical TUES and offers better cosmetic results.
キーワード laparoscopy cholecystectomy scarless surgery
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
巻 65巻
号 5号
出版者 Okayama University Medical School
開始ページ 325
終了ページ 328
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037269
Web of Science KeyUT 000296116400006
JaLCDOI 10.18926/AMO/47013
フルテキストURL 65_5_315.pdf
著者 Wang, Lei| Kaku, Haruki| Huang, Peng| Xu, Kexin| Yang, Kai| Zhang, Jiheng| Li, Ming| Xie, Liping| Wang, Xiaofeng| Sakai, Akiko| Watanabe, Masami| Nasu, Yasutomo| Shimizu, Kenji| Kumon, Hiromi| Na, Yanqun|
抄録 Deficiencies in the human DNA repair gene WRN are the cause of Werner syndrome, a rare autosomal recessive disorder characterized by premature aging and a predisposition to cancer. This study evaluated the association of WRN Leu1074Phe (rs1801195), a common missense single nucleotide polymorphism in WRN, with prostate cancer susceptibility in Chinese subjects. One hundred and forty-seven prostate cancer patients and 111 male cancer-free control subjects from 3 university hospitals in China were included. Blood samples were obtained from each subject, and the single nucleotide polymorphism WRN Leu1074Phe was genotyped by using a Snapshot assay. The results showed that WRN Leu1074Phe was associated with the risk of prostate cancer in Chinese men and that the TG/GG genotype displayed a decreased prevalence of prostate cancer compared with the TT genotype (OR=0.58, 95%CI:0.35-0.97, p=0.039). Through stratified analysis, more significant associations were revealed for the TG/GG genotype in the subgroup with diagnosis age <_ 72 yr (OR=0.27, 95%CI:0.12-0.61, p=0.002) and in patients with localized diseases (OR=0.36, 95%CI:0.19-0.70, p=0.003). However, no statistically significant difference was found in the subgroup with age >72 yr or in patients with advanced diseases. We concluded that the genetic variant Leu1074Phe in the DNA repair gene WRN might play a role in the risk of prostate cancer in Chinese subjects.
キーワード polymorphism prostatic neoplasms single nucleotide susceptibility WRN
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
巻 65巻
号 5号
出版者 Okayama University Medical School
開始ページ 315
終了ページ 323
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037267
Web of Science KeyUT 000296116400005
JaLCDOI 10.18926/AMO/47011
フルテキストURL 65_5_299.pdf
著者 Itani, Miki| Yamamoto, Yuji| Doi, Yusuke| Miyaishi, Satoru|
抄録 Postmortem degradation of DNA was quantitatively estimated. Brain, liver, kidney and muscle samples were obtained from sacrificed rats left at 20℃ or 4℃. The quantity of DNA was measured by real-time PCR using a primer set for a sequence in the Rsrc 1 gene. When the quantity of amplified DNA using 10ng Human Genomic DNA was defined as 100 RFU, the quantities in the brain, liver, kidney and skeletal muscle (each 2μg of dry weight) on the day of sacrifice were 253±11, 338±22, 556±14 and 531±12 Relative Fluorescence Units (RFU), respectively (mean±S.E., n=5). The quantity of amplified DNA decreased to below 10 RFU in 1-3 weeks in the liver, kidney and skeletal muscle at 20℃, while that in the brain was more than 10 RFU for six weeks, demonstrating the usefulness of the brain as a sample for DNA analysis of decaying corpses. It was suggested that quantifying the amplified DNA in the brain at 20℃ and in the liver at 4℃ as well as the ratio of the quantity of amplified DNA in the liver to the brain at 4℃ might be useful for diagnosing time of death. This study provides the first quantitative analysis of the postmortem progress of DNA degradation in the corpse.
キーワード DNA degradation postmortem interval personal identification
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
巻 65巻
号 5号
出版者 Okayama University Medical School
開始ページ 299
終了ページ 306
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037266
Web of Science KeyUT 000296116400003
JaLCDOI 10.18926/AMO/47009
フルテキストURL 65_5_279.pdf
著者 Miyoshi, Ko| Kasahara, Kyosuke| Miyazaki, Ikuko| Asanuma, Masato|
抄録 Almost all mammalian cells carry one primary cilium that functions as a biosensor for chemical and mechanical stimuli. Genetic damages that compromise cilia formation or function cause a spectrum of disorders referred to as ciliapathies. Recent studies have demonstrated that some pharmacological agents and extracellular environmental changes can alter primary cilium length. Renal injury is a well-known example of an environmental insult that triggers cilia length modification. Lithium treatment causes primary cilia to extend in several cell types including neuronal cells;this phenomenon is likely independent of glycogen synthase kinase-3β inhibition. In renal epithelial cell lines, deflection of the primary cilia by fluid shear shortens them by reducing the intracellular cyclic AMP level, leading to a subsequent decrease in mechanosensitivity to fluid shear. Primary cilium length is also influenced by the dynamics of actin filaments and microtubules through the levels of soluble tubulin in the cytosol available for primary cilia extension. Thus, mammalian cells can adapt to the extracellular environment by modulating the primary cilium length, and this feedback system utilizing primary cilia might exist throughout the mammalian body. Further investigation is required concerning the precise molecular mechanisms underlying the control of primary cilium length in response to environmental factors.
キーワード primary cilium length lithium cyclic AMP soluble tubulin intraflagellar transport
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2011-10
巻 65巻
号 5号
出版者 Okayama University Medical School
開始ページ 279
終了ページ 285
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037264
Web of Science KeyUT 000296116400001
著者 Tsukamoto, Naoko| Otsuka, Fumio| Miyoshi, Tomoko| Inagaki, Kenichi| Nakamura, Eri| Suzuki, Jiro| Ogura, Toshio| Iwasaki, Yasumasa| Makino, Hirofumi|
発行日 2011-01-30
出版物タイトル Molecular and Cellular Endocrinology
巻 332巻
号 1-2号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/46997
フルテキストURL mfe_36_1_017_028.pdf
著者 Endo, Shinichiro| Konishi, Masami|
抄録 Small Scale Hydroelectric Power Generation is made using the water drop caused by the gradient difference between that of the river and that of the penstock. The water flow in this system apt to vary with time. Especially, at the time of the flood or that of the dry, the flow in the water stream varies largely. To realize the stable generation, it is necessary to maintain the water level in the head tank located in the mid way in the stream channel at a constant level. In this paper, variation of water level is forecasted using two-tank model for the penstock and the head tank and the water level control algorithm is proposed by deadbeat control. The effectiveness of the algorithm is evaluated beforehand using the simulation program of the water environment for the hydroelectric generation system.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
巻 36巻
号 1号
開始ページ 17
終了ページ 28
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497023
JaLCDOI 10.18926/46996
フルテキストURL mfe_36_1_007_016.pdf
著者 Li, Yan| Abe, Takeji| Tada, Naoya| Kanazawa, Masanori|
抄録 The change in the surface morphology of polycrystalline titanium during tensile plastic deformation is studied, using the scanning probe microscope as well as the laser scanning microscope. The observation shows that the slip occurs mainly near grain boundary at the strain range of ε < 0.05. The slip develops with the applied strain, and the slip on the second slip system or the crossing of slip lines appear. The surface roughness increases linearly with the applied strain. The height difference between the grain boundary area and the inner grain area also increases with the applied strain, though the increase rate becomes low after the applied strain of about 0.3. The nano-scale height difference of the surface step of slip lines increases with the applied strain, though it remains almost constant after the applied strain of 0.4. The averaged surface roughness measured with the scanning probe microscope is in good agreement with that measured with the laser scanning microscope.
キーワード Plasticity Polycrystalline Titanium Tensile Deformation Surface Morphology Slip Twin Probe Scanning Microscope Laser Scanning Microscope
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
巻 36巻
号 1号
開始ページ 7
終了ページ 16
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80012831215
JaLCDOI 10.18926/46979
フルテキストURL mfe_37_2_045_060.pdf
著者 Xu, Wei| Zhao, Y.| Horikane, T.| Hayata, T.| Tosuji, H.| Kagawa, Y.|
抄録 Resistivity distribution sounding of the non-homogeneous earth is important for electrical ground system design, geophysical prospecting and survey or monitoring the groundwater flow level. The previous paper presented that the direct inversion of the electric resistivity distribution in a domain is possible from the impedance data measured over the domain boundary using the dual reciprocity boundary element modelling in two-dimentional field [1]. The proposed inversion technique is extended to the distribution in three-dimensional space [2]. This technique is capable of inversion without iteration and meshing of the domain. Electric field with spatially varying conductivity is governed by Laplace equation, which is transformed into a Poisson-type expression with an inhomogeneous term involving the conductivity difference as a source term. Dual reciprocity method (DRM) is a technique for transforming the domain integral associated with the inhomogeneous term in Poisson equation into the boundary integral expression. The resistivity distribution in the field can thus be identified from the data observed over its boundary, for which some examples are demonstrated [2]. In this paper, the examination is extended to the case where only the data measured over the single surface is used for the inversion.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2003-03
巻 37巻
号 2号
開始ページ 45
終了ページ 60
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80016037881
JaLCDOI 10.18926/46977
フルテキストURL mfe_37_2_013_027.pdf
著者 Shibuta, Taizo| Konishi, Masami| Imai, Jun| Nishi, Tatsushi|
抄録 Nowadays, various kind of reactor furnaces are widely used for the production in industry. The raw materials charged into the furnace generate reaction heat produced by blowing gas. Generally speaking, the reaction heat generated in the furnace is remarkably high. Therefore the occurrence of an inappropriate temperature distribution in the furnace may make damege or serious accident of the furnace. This is the motivation of furnace control. The author is considering the application of studied results to the furnace control of Blast Furnace in steel industry. To the propose, the approximated and simplified Macro Model of the Blast Furnace is constructed which has the function of representation of qualitative characteristics of the furnace in dynamical sense. The furnace temperature, distribution greatly effects both on the producting and the product quality of the furnace. Needless to say, stable furnace operation is indispensable for the economical prosperity of the industry. In this paper, macro simulation of the furnace is developed to support the analysis and design of the furnace control. Using the simulator, the stability and the control characteristics for inner furnace temperature distribtion are analised quantitatively.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2003-03
巻 37巻
号 2号
開始ページ 13
終了ページ 27
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80015999991
JaLCDOI 10.18926/46975
フルテキストURL mfe_37_2_001_004.pdf
著者 Sakakibara, Akira| Kanadani, Teruto|
抄録 Effect of addition of Fe on the occurrence of serration in Al-12mass%Zn alloys was investigated. Specimens aged at 293K for various periods after quenching from various temperatures (T(Q)), 398K to 823K, were tensile-tested at room temperature. Serration occurred more easily and more remarkably with decreasing T(Q) for as-quenched specimens: in the case that T(Q)=448K serration was observed both for the binary and Fe added alloys, while in the case that T(Q)=573K none of the three alloys showed serration. For the binary alloy serration was observed only when the aging period was short enough, but addition of Fe to the binary alloy prolonged the aging period where serration could be recognized. Aging rate measured by hardness was remarkably retarded with the increase of Fe addition. These results confirm the interpretation that the serration in Al-Zn alloy occurs in the early stage of aging where small GP zones or solute clusters are formed.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2003-03
巻 37巻
号 2号
開始ページ 1
終了ページ 4
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80016019142
JaLCDOI 10.18926/46967
フルテキストURL mfe_37_1_001_010.pdf
著者 Sotobayashi, Ken| Konishi, Masami| Nishi, Tatsushi| Imai, Jun|
抄録 Auto Guided Vehicles (AGVs) are widely used in a semi-conductor fabricating factory and contribute to the stable production of a high quality semi-conductor products. In the near future, further expansion of the transportation system is expected accompanied with the rapid growth of semi-conductor industries. In such situation, the necessity of performing quick planning of transportation route and transportation control will be elevated. In this paper, practicable planning of the transportation route and transportation control are studied based on the decentralized agent method. Especially, the geometrical sizes of AGVs are considered in the determination of transportation routes and control strategy avoiding the occurrence of mutual collisions or deadlock of AGVs.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2002-11
巻 37巻
号 1号
開始ページ 1
終了ページ 10
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003457322
著者 Yorifuji, Takashi| Tsuda, Toshihide| Inoue, Sachiko| Takao, Soshi| Harada, Masazumi|
発行日 2011-07
出版物タイトル Environment International
巻 37巻
号 5号
資料タイプ 学術雑誌論文
著者 Yorimitsu, Takeshi| Kiritooshi, Naruto| Nakagoshi, Hideki|
発行日 2011-08-15
出版物タイトル Developmental Biology
巻 356巻
号 2号
資料タイプ 学術雑誌論文
著者 Ishimoto, Hidekazu| Shibata, Mari| Myojin, Yuki| Ito, Hideyuki| Sugimoto, Yukio| Tai, Akihiro| Hatano, Tsutomu|
発行日 2011-10-01
出版物タイトル Bioorganic & Medicinal Chemistry Letters
巻 21巻
号 19号
資料タイプ 学術雑誌論文