
検索結果 135 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Maeda, Yukihide| Takao, Soshi| Omichi, Ryotaro| Ando, Mizuo| |
| キーワード | aspartate aminotransferase-to-platelet ratio index audiometry fatty liver disease incidence liver fibrosis-4 index severity sudden hearing loss |
| 発行日 | 2025-08-12 |
| 出版物タイトル | Cureus |
| 巻 | 17巻 |
| 号 | 8号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | e89864 |
| ISSN | 2168-8184 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Copyright 2025 Maeda et al. |
| 論文のバージョン | publisher |
| PubMed ID | 40951216 |
| DOI | 10.7759/cureus.89864 |
| 関連URL | isVersionOf https://doi.org/10.7759/cureus.89864 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nagao, Koki| Takahashi, Taku| Yokoyama, Ryusuke| |
| キーワード | Cuscuta Environmental conditions Germination Hormone responses Seedling growth |
| 備考 | The version of record of this article, first published in Plant Growth Regulation, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10725-025-01331-5| |
| 発行日 | 2025-05-05 |
| 出版物タイトル | Plant Growth Regulation |
| 巻 | 105巻 |
| 号 | 4号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 1157 |
| 終了ページ | 1167 |
| ISSN | 0167-6903 |
| NCID | AA10632764 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2025 |
| 論文のバージョン | publisher |
| DOI | 10.1007/s10725-025-01331-5 |
| Web of Science KeyUT | 001481348000001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s10725-025-01331-5 |
| フルテキストURL | fulltext.pdf suppl1.pdf suppl2.xlsx |
|---|---|
| 著者 | Nguyen Thao, Tran| Mitani-Ueno, Namiki| Urano, Ryo| Saitoh, Yasunori| Wang, Peitong| Yamaji, Naoki| Shen, Jian-Ren| Shinoda, Wataru| Ma, Jian Feng| Suga, Michihiro| |
| キーワード | barley aluminum resistance membrane protein structure citrate transporter MATE transporter |
| 発行日 | 2025-08-05 |
| 出版物タイトル | Proceedings of the National Academy of Sciences |
| 巻 | 122巻 |
| 号 | 32号 |
| 出版者 | Proceedings of the National Academy of Sciences |
| 開始ページ | e2501933122 |
| ISSN | 0027-8424 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2025 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 40763023 |
| DOI | 10.1073/pnas.2501933122 |
| 関連URL | isVersionOf https://doi.org/10.1073/pnas.2501933122 |
| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| フルテキストURL | 78_5_387.pdf |
| 著者 | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| 抄録 | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| キーワード | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 387 |
| 終了ページ | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467657 |
| Web of Science KeyUT | 001343346400005 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nakashima, Mitsutaka| Miyoshi, Toru| Tanakaya, Machiko| Saito, Takaaki| Katayama, Yusuke| Sakuragi, Satoru| Takaya, Yoichi| Ito, Hiroshi| |
| キーワード | Liver disorder Fibrosis-4 index Fibrosis-5 index Isolated tricuspid regurgitation Major adverse cardiac events |
| 備考 | The version of record of this article, first published in Heart and Vessels, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00380-023-02268-3| |
| 発行日 | 2023-04-23 |
| 出版物タイトル | Heart and Vessels |
| 巻 | 38巻 |
| 号 | 9号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 1181 |
| 終了ページ | 1189 |
| ISSN | 0910-8327 |
| NCID | AA10452161 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 37087702 |
| DOI | 10.1007/s00380-023-02268-3 |
| Web of Science KeyUT | 000974679600001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s00380-023-02268-3 |
| フルテキストURL | fulltext20231110-02.pdf |
|---|---|
| 著者 | Hasegawa, Kosei| Futagawa, Natsuko| Ago, Yuko| Miyahara, Hiroyuki| Harada, Daisuke| Miyazawa, Mari| Yoshimoto, Junko| Baba, Kenji| Moriwake, Tadashi| Tanaka, Hiroyuki| Tsukahara, Hirokazu| |
| キーワード | infant skeleton spine cartilage growth |
| 発行日 | 2023 |
| 出版物タイトル | Clinical Pediatric Endocrinology |
| 巻 | 32巻 |
| 号 | 4号 |
| 出版者 | Japanese Society for Pediatric Endocrinology |
| 開始ページ | 221 |
| 終了ページ | 227 |
| ISSN | 0918-5739 |
| NCID | AA11006467 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by The Japanese Society for Pediatric Endocrinology |
| 論文のバージョン | publisher |
| PubMed ID | 37842142 |
| DOI | 10.1297/cpe.2023-0035 |
| Web of Science KeyUT | 001085272200003 |
| 関連URL | isVersionOf https://doi.org/10.1297/cpe.2023-0035 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Sumi, Tomonari| Harada, Kouji| |
| 発行日 | 2023-03-17 |
| 出版物タイトル | iScience |
| 巻 | 26巻 |
| 号 | 3号 |
| 出版者 | Cell Press |
| 開始ページ | 106133 |
| ISSN | 2589-0042 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 36866246 |
| DOI | 10.1016/j.isci.2023.106133 |
| Web of Science KeyUT | 000993415200001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.isci.2023.106133 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Gathinji, Peter Kiiru| Yousofi, Zabiallah| Akada, Karin| Wali, Ajmal| Nishino, Naoki| |
| キーワード | airborne dust blood metabolites Jersey cows microbiota milk |
| 発行日 | 2023-03-16 |
| 出版物タイトル | Veterinary Sciences |
| 巻 | 10巻 |
| 号 | 3号 |
| 出版者 | MDPI |
| 開始ページ | 226 |
| ISSN | 2306-7381 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 36977265 |
| DOI | 10.3390/vetsci10030226 |
| Web of Science KeyUT | 000960149500001 |
| 関連URL | isVersionOf https://doi.org/10.3390/vetsci10030226 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Akil, Caner| Tran, Linh T.| Orhant-Prioux, Magali| Baskaran, Yohendran| Senju, Yosuke| Takeda, Shuichi| Chotchuang, Phatcharin| Muengsaen, Duangkamon| Schulte, Albert| Manser, Edward| Blanchoin, Laurent| Robinson, Robert C.| |
| 発行日 | 2022-08-31 |
| 出版物タイトル | Communications Biology |
| 巻 | 5巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 890 |
| ISSN | 2399-3642 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2022 |
| 論文のバージョン | publisher |
| PubMed ID | 36045281 |
| DOI | 10.1038/s42003-022-03783-1 |
| Web of Science KeyUT | 000849355300002 |
| 関連URL | isVersionOf https://doi.org/10.1038/s42003-022-03783-1 |
| JaLCDOI | 10.18926/AMO/63203 |
|---|---|
| フルテキストURL | 76_1_7.pdf |
| 著者 | Takami, Masao| Yamamoto, Koichiro| Hanayama, Yoshihisa| Nakano, Yasuhiro| Hasegawa, Kou| Obika, Mikako| Hagiya, Hideharu| Furukawa, Masanori| Otsuka, Fumio| |
| 抄録 | Subclinical hypothyroidism (SCH) is diagnosed when serum thyrotropin (TSH) is elevated despite a normal thyroxine level and is known to increase the risk of metabolic disorders. This study was conducted to identify potential laboratory markers suspicious for latent SCH. We retrospectively reviewed 958 outpatients in whom thyroid functions had been examined. Eighty-five (9.1%) of the 939 analyzed subjects had SCH (73% females). In the SCH group, median serum TSH and FT4 levels were 5.04 μU/ml and 1.19 ng/dl, respectively, and auto-thyroid antibodies were detected in 53.8% of patients. SCH group patients were significantly older than patients in the euthyroid group, while there was no intergroup difference in BMI. However, 56.5% of the SCH patients were asymptomatic. In the SCH group, serum aspartate aminotransferase and low-density lipoprotein cholesterol (LDL-C) levels were significantly higher, and the estimated glomerular filtration rate (eGFR) was significantly lower than in the euthyroid group. Among patients less than 65 years of age, SCH patients tended to have lower eGFR and higher LDL-C than euthyroid patients. Age-dependent reductions of red blood cells and serum albumin were more prominent in the SCH than the euthyroid group. Biochemical changes with aging are useful as potential clues for suspecting latent SCH. |
| キーワード | aging renal function cholesterol subclinical hypothyroidism thyroid function |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-02 |
| 巻 | 76巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 7 |
| 終了ページ | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35236993 |
| Web of Science KeyUT | 000762812700002 |
| フルテキストURL | fulltext20210525_2.pdf |
|---|---|
| 著者 | El-Aarag, Bishoy| El-Saied, Fathy| Salem, Tarek| Khedr, Nesrin| Khalifa, Shaden A.M.| El-Seedi, Hesham R.| |
| キーワード | Metal complexes Thiosemicarbazone Antitumor Ehrlich tumor Ki67 P53 |
| 発行日 | 2021-03-31 |
| 出版物タイトル | Arabian Journal of Chemistry |
| 巻 | 14巻 |
| 号 | 3号 |
| 出版者 | Elsevier |
| 開始ページ | 102993 |
| ISSN | 18785352 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Author(s). |
| 論文のバージョン | publisher |
| DOI | 10.1016/j.arabjc.2021.102993 |
| NAID | 120007039928 |
| Web of Science KeyUT | 000623519700026 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.arabjc.2021.102993 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Harada, Daijiro| Isozaki, Hideko| Kozuki, Toshiyuki| Yokoyama, Toshihide| Yoshioka, Hiroshige| Bessho, Akihiro| Hosokawa, Shinobu| Takata, Ichiro| Takigawa, Nagio| Hotta, Katsuyuki| Kiura, Katsuyuki| Okayama Lung Cancer Study Group| |
| キーワード | Alectinib anaplastic lymphoma kinase crizotinib drug therapy non-small cell lung carcinoma |
| 発行日 | 2021-01-20 |
| 出版物タイトル | Thoracic Cancer |
| 巻 | 12巻 |
| 号 | 5号 |
| 出版者 | Wiley |
| 開始ページ | 643 |
| 終了ページ | 649 |
| ISSN | 1759-7706 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 33470536 |
| DOI | 10.1111/1759-7714.13825 |
| Web of Science KeyUT | 000608856400001 |
| 関連URL | isVersionOf https://doi.org/10.1111/1759-7714.13825 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Sumi, Tomonari| Harada, Kouji| |
| キーワード | Biophysical models Long-term depression Long-term potentiation |
| 発行日 | 2020-09-07 |
| 出版物タイトル | Scientific Reports |
| 巻 | 10巻 |
| 号 | 1号 |
| 出版者 | Nature |
| 開始ページ | 14711 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2020 |
| 論文のバージョン | publisher |
| PubMed ID | 32895399 |
| DOI | 10.1038/s41598-020-71528-3 |
| Web of Science KeyUT | 000570970200006 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-020-71528-3 |
| JaLCDOI | 10.18926/AMO/60368 |
|---|---|
| フルテキストURL | 74_4_301.pdf |
| 著者 | Takahashi, Kei| Kitamura, Yoshihisa| Ushio, Soichiro| Sendo, Toshiaki| |
| 抄録 | Ketamine has been clinically proven to ameliorate depression, including treatment-resistant depression. The detailed mechanism of action of ketamine in treatment-resistant depression remains unclear. We examined the effects of ketamine on the immobility times of adrenocorticotropic hormone (ACTH)-treated rats during the forced swim test, and we explored the mechanism by which ketamine acts in this model. We investigated the neuroanatomical site of action by microinjecting ketamine into the medial prefrontal cortex of rats. A significant reduction of the rats’ immobility during the forced swim test was observed after the intraperitoneal injection of ketamine in both saline- and ACTH-treated rats. The microinjection of ketamine into the medial prefrontal cortex also decreased immobility during the forced swim test in both saline- and ACTH-treated rats. The immobility-decreasing effect of intraperitoneally injected ketamine was blocked by administering WAY100635, a 5-HT1A receptor antagonist, into the medial prefrontal cortex. These findings contribute to the evidence that ketamine can be useful against treatment-resistant depressive conditions. The immobility-reducing effects of ketamine might be mediated by 5-HT1A receptor activity in the medial prefrontal cortex. |
| キーワード | ketamine adrenocorticotropic hormone forced swim test medial prefrontal cortex 5-HT1A receptor |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-08 |
| 巻 | 74巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 301 |
| 終了ページ | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32843761 |
| Web of Science KeyUT | 000562508700005 |
| NAID | 120006880207 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nakamura, Shunsuke| Matsuno, Aya| Ueda, Masashi| |
| キーワード | αvβ6 integrin Pancreatic ductal adenocarcinoma (PDAC) A20FMDV2 Aspartic acids Electric charge |
| 備考 | This is a post-peer-review, pre-copyedit version of an article published in Annals of Nuclear Medicine. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12149-020-01483-6.| |
| 発行日 | 2020-06-08 |
| 出版物タイトル | Annals of Nuclear Medicine |
| 巻 | 34巻 |
| 出版者 | Springer |
| 開始ページ | 575 |
| 終了ページ | 582 |
| ISSN | 0914-7187 |
| NCID | AA10708017 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 32514725 |
| DOI | 10.1007/s12149-020-01483-6 |
| Web of Science KeyUT | 000539348100001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s12149-020-01483-6 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | El-Saied, Fathy| El-Aarag, Bishoy| Salem, Tarek| Said, Ghada| Khalifa, Shaden A. M.| El-Seedi, Hesham R.| |
| キーワード | metal complexes isatin-N(4)antipyrinethiosemicarbazone Ehrlich ascites carcinoma tumor volume VEGF caspase-7 |
| 発行日 | 2019-09-11 |
| 出版物タイトル | Molecules |
| 巻 | 24巻 |
| 号 | 18号 |
| 出版者 | MDPI |
| ISSN | 1420-3049 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 31514445 |
| DOI | 10.3390/molecules24183313 |
| Web of Science KeyUT | 000488830500105 |
| 関連URL | isVersionOf https://doi.org/10.3390/molecules24183313 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | El-Aarag, Bishoy| Khairy, Asmaa| Khalifa, Shaden A. M.| El-Seedi, Hesham R.| |
| キーワード | liver injury CCl4 Tamarix aphylla oxidative stress apoptosis angiogenesis |
| 発行日 | 2019-10-21 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 20巻 |
| 号 | 20号 |
| 出版者 | MDPI |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 31640181 |
| DOI | 10.3390/ijms20205215 |
| Web of Science KeyUT | 000498822800247 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms20205215 |
| フルテキストURL | MIB21_3_519.pdf |
|---|---|
| 著者 | Matsuura, Yuki| Ueda, Masashi| Higaki, Yusuke| Sano, Kohei| Saji, Hideo| Enomoto, Shuichi| |
| キーワード | Alzheimer's disease Nicotinic acetylcholine receptors 2-Deoxy-2-[F-18]fluoro-D-glucose ([F-18]FDG) 5-[I-123]Iodo-3-[2(S)-azetidinylmethoxy]pyridine ([I-123]5IA) APP PS2 mice |
| 発行日 | 2018-07-25 |
| 出版物タイトル | Molecular Imaging and Biology |
| 巻 | 21巻 |
| 号 | 3号 |
| 出版者 | Springer |
| 開始ページ | 519 |
| 終了ページ | 528 |
| ISSN | 1536-1632 |
| NCID | AA1170000X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 30047036 |
| DOI | 10.1007/s11307-018-1253-4 |
| Web of Science KeyUT | 000468363800015 |
| 関連URL | isVersionOf https://doi.org/10.1007/s11307-018-1253-4 |
| フルテキストURL | Biomed_Pharmacother_2019109038.pdf |
|---|---|
| 著者 | Ueno, Hiroshi| Suemitsu, Shunsuke| Murakami, Shinji| Kitamura, Naoya| Wani, Kenta| Takahashi, Yu| Matsumoto, Yosuke| Okamoto, Motoi| Ishihara, Takeshi| |
| キーワード | Inhalation Dizocilpine MK-801 Mouse Drug Schizophrenia |
| 発行日 | 2019-09-30 |
| 出版物タイトル | Biomedicine & Pharmacotherapy |
| 巻 | 117巻 |
| 出版者 | Elsevier |
| 開始ページ | 109038 |
| ISSN | 07533322 |
| NCID | AA10506249 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 The Authors. Published by Elsevier Masson SAS. |
| 論文のバージョン | publisher |
| PubMed ID | 31177060 |
| DOI | 10.1016/j.biopha.2019.109038 |
| Web of Science KeyUT | 000477804500018 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.biopha.2019.109038 |
| JaLCDOI | 10.18926/AMO/56860 |
|---|---|
| フルテキストURL | 73_3_189.pdf |
| 著者 | Sakamoto, Shinji| Kawai, Hiroki| Okahisa, Yuko| Tsutsui, Ko| Kanbayashi, Takashi| Tanaka, Keiko| Mizuki, Yutaka| Takaki, Manabu| Yamada, Norihito| |
| 抄録 | Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti-NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry. |
| キーワード | NMDAR encephalitis psychiatric symptom schizophrenia mood disorder |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-06 |
| 巻 | 73巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 189 |
| 終了ページ | 195 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31235965 |