result 135 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Maeda, Yukihide| Takao, Soshi| Omichi, Ryotaro| Ando, Mizuo| |
| Keywords | aspartate aminotransferase-to-platelet ratio index audiometry fatty liver disease incidence liver fibrosis-4 index severity sudden hearing loss |
| Published Date | 2025-08-12 |
| Publication Title | Cureus |
| Volume | volume17 |
| Issue | issue8 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | e89864 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Copyright 2025 Maeda et al. |
| File Version | publisher |
| PubMed ID | 40951216 |
| DOI | 10.7759/cureus.89864 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.89864 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nagao, Koki| Takahashi, Taku| Yokoyama, Ryusuke| |
| Keywords | Cuscuta Environmental conditions Germination Hormone responses Seedling growth |
| Note | The version of record of this article, first published in Plant Growth Regulation, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10725-025-01331-5| |
| Published Date | 2025-05-05 |
| Publication Title | Plant Growth Regulation |
| Volume | volume105 |
| Issue | issue4 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1157 |
| End Page | 1167 |
| ISSN | 0167-6903 |
| NCID | AA10632764 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025 |
| File Version | publisher |
| DOI | 10.1007/s10725-025-01331-5 |
| Web of Science KeyUT | 001481348000001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10725-025-01331-5 |
| FullText URL | fulltext.pdf suppl1.pdf suppl2.xlsx |
|---|---|
| Author | Nguyen Thao, Tran| Mitani-Ueno, Namiki| Urano, Ryo| Saitoh, Yasunori| Wang, Peitong| Yamaji, Naoki| Shen, Jian-Ren| Shinoda, Wataru| Ma, Jian Feng| Suga, Michihiro| |
| Keywords | barley aluminum resistance membrane protein structure citrate transporter MATE transporter |
| Published Date | 2025-08-05 |
| Publication Title | Proceedings of the National Academy of Sciences |
| Volume | volume122 |
| Issue | issue32 |
| Publisher | Proceedings of the National Academy of Sciences |
| Start Page | e2501933122 |
| ISSN | 0027-8424 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 the Author(s). |
| File Version | publisher |
| PubMed ID | 40763023 |
| DOI | 10.1073/pnas.2501933122 |
| Related Url | isVersionOf https://doi.org/10.1073/pnas.2501933122 |
| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| FullText URL | 78_5_387.pdf |
| Author | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| Abstract | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| Keywords | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467657 |
| Web of Science KeyUT | 001343346400005 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakashima, Mitsutaka| Miyoshi, Toru| Tanakaya, Machiko| Saito, Takaaki| Katayama, Yusuke| Sakuragi, Satoru| Takaya, Yoichi| Ito, Hiroshi| |
| Keywords | Liver disorder Fibrosis-4 index Fibrosis-5 index Isolated tricuspid regurgitation Major adverse cardiac events |
| Note | The version of record of this article, first published in Heart and Vessels, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00380-023-02268-3| |
| Published Date | 2023-04-23 |
| Publication Title | Heart and Vessels |
| Volume | volume38 |
| Issue | issue9 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1181 |
| End Page | 1189 |
| ISSN | 0910-8327 |
| NCID | AA10452161 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37087702 |
| DOI | 10.1007/s00380-023-02268-3 |
| Web of Science KeyUT | 000974679600001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00380-023-02268-3 |
| FullText URL | fulltext20231110-02.pdf |
|---|---|
| Author | Hasegawa, Kosei| Futagawa, Natsuko| Ago, Yuko| Miyahara, Hiroyuki| Harada, Daisuke| Miyazawa, Mari| Yoshimoto, Junko| Baba, Kenji| Moriwake, Tadashi| Tanaka, Hiroyuki| Tsukahara, Hirokazu| |
| Keywords | infant skeleton spine cartilage growth |
| Published Date | 2023 |
| Publication Title | Clinical Pediatric Endocrinology |
| Volume | volume32 |
| Issue | issue4 |
| Publisher | Japanese Society for Pediatric Endocrinology |
| Start Page | 221 |
| End Page | 227 |
| ISSN | 0918-5739 |
| NCID | AA11006467 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by The Japanese Society for Pediatric Endocrinology |
| File Version | publisher |
| PubMed ID | 37842142 |
| DOI | 10.1297/cpe.2023-0035 |
| Web of Science KeyUT | 001085272200003 |
| Related Url | isVersionOf https://doi.org/10.1297/cpe.2023-0035 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sumi, Tomonari| Harada, Kouji| |
| Published Date | 2023-03-17 |
| Publication Title | iScience |
| Volume | volume26 |
| Issue | issue3 |
| Publisher | Cell Press |
| Start Page | 106133 |
| ISSN | 2589-0042 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Author(s). |
| File Version | publisher |
| PubMed ID | 36866246 |
| DOI | 10.1016/j.isci.2023.106133 |
| Web of Science KeyUT | 000993415200001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.isci.2023.106133 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Gathinji, Peter Kiiru| Yousofi, Zabiallah| Akada, Karin| Wali, Ajmal| Nishino, Naoki| |
| Keywords | airborne dust blood metabolites Jersey cows microbiota milk |
| Published Date | 2023-03-16 |
| Publication Title | Veterinary Sciences |
| Volume | volume10 |
| Issue | issue3 |
| Publisher | MDPI |
| Start Page | 226 |
| ISSN | 2306-7381 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36977265 |
| DOI | 10.3390/vetsci10030226 |
| Web of Science KeyUT | 000960149500001 |
| Related Url | isVersionOf https://doi.org/10.3390/vetsci10030226 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Akil, Caner| Tran, Linh T.| Orhant-Prioux, Magali| Baskaran, Yohendran| Senju, Yosuke| Takeda, Shuichi| Chotchuang, Phatcharin| Muengsaen, Duangkamon| Schulte, Albert| Manser, Edward| Blanchoin, Laurent| Robinson, Robert C.| |
| Published Date | 2022-08-31 |
| Publication Title | Communications Biology |
| Volume | volume5 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 890 |
| ISSN | 2399-3642 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 36045281 |
| DOI | 10.1038/s42003-022-03783-1 |
| Web of Science KeyUT | 000849355300002 |
| Related Url | isVersionOf https://doi.org/10.1038/s42003-022-03783-1 |
| JaLCDOI | 10.18926/AMO/63203 |
|---|---|
| FullText URL | 76_1_7.pdf |
| Author | Takami, Masao| Yamamoto, Koichiro| Hanayama, Yoshihisa| Nakano, Yasuhiro| Hasegawa, Kou| Obika, Mikako| Hagiya, Hideharu| Furukawa, Masanori| Otsuka, Fumio| |
| Abstract | Subclinical hypothyroidism (SCH) is diagnosed when serum thyrotropin (TSH) is elevated despite a normal thyroxine level and is known to increase the risk of metabolic disorders. This study was conducted to identify potential laboratory markers suspicious for latent SCH. We retrospectively reviewed 958 outpatients in whom thyroid functions had been examined. Eighty-five (9.1%) of the 939 analyzed subjects had SCH (73% females). In the SCH group, median serum TSH and FT4 levels were 5.04 μU/ml and 1.19 ng/dl, respectively, and auto-thyroid antibodies were detected in 53.8% of patients. SCH group patients were significantly older than patients in the euthyroid group, while there was no intergroup difference in BMI. However, 56.5% of the SCH patients were asymptomatic. In the SCH group, serum aspartate aminotransferase and low-density lipoprotein cholesterol (LDL-C) levels were significantly higher, and the estimated glomerular filtration rate (eGFR) was significantly lower than in the euthyroid group. Among patients less than 65 years of age, SCH patients tended to have lower eGFR and higher LDL-C than euthyroid patients. Age-dependent reductions of red blood cells and serum albumin were more prominent in the SCH than the euthyroid group. Biochemical changes with aging are useful as potential clues for suspecting latent SCH. |
| Keywords | aging renal function cholesterol subclinical hypothyroidism thyroid function |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 7 |
| End Page | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35236993 |
| Web of Science KeyUT | 000762812700002 |
| FullText URL | fulltext20210525_2.pdf |
|---|---|
| Author | El-Aarag, Bishoy| El-Saied, Fathy| Salem, Tarek| Khedr, Nesrin| Khalifa, Shaden A.M.| El-Seedi, Hesham R.| |
| Keywords | Metal complexes Thiosemicarbazone Antitumor Ehrlich tumor Ki67 P53 |
| Published Date | 2021-03-31 |
| Publication Title | Arabian Journal of Chemistry |
| Volume | volume14 |
| Issue | issue3 |
| Publisher | Elsevier |
| Start Page | 102993 |
| ISSN | 18785352 |
| Content Type | Journal Article |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Author(s). |
| File Version | publisher |
| DOI | 10.1016/j.arabjc.2021.102993 |
| NAID | 120007039928 |
| Web of Science KeyUT | 000623519700026 |
| Related Url | isVersionOf https://doi.org/10.1016/j.arabjc.2021.102993 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Harada, Daijiro| Isozaki, Hideko| Kozuki, Toshiyuki| Yokoyama, Toshihide| Yoshioka, Hiroshige| Bessho, Akihiro| Hosokawa, Shinobu| Takata, Ichiro| Takigawa, Nagio| Hotta, Katsuyuki| Kiura, Katsuyuki| Okayama Lung Cancer Study Group| |
| Keywords | Alectinib anaplastic lymphoma kinase crizotinib drug therapy non-small cell lung carcinoma |
| Published Date | 2021-01-20 |
| Publication Title | Thoracic Cancer |
| Volume | volume12 |
| Issue | issue5 |
| Publisher | Wiley |
| Start Page | 643 |
| End Page | 649 |
| ISSN | 1759-7706 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 33470536 |
| DOI | 10.1111/1759-7714.13825 |
| Web of Science KeyUT | 000608856400001 |
| Related Url | isVersionOf https://doi.org/10.1111/1759-7714.13825 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sumi, Tomonari| Harada, Kouji| |
| Keywords | Biophysical models Long-term depression Long-term potentiation |
| Published Date | 2020-09-07 |
| Publication Title | Scientific Reports |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Nature |
| Start Page | 14711 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2020 |
| File Version | publisher |
| PubMed ID | 32895399 |
| DOI | 10.1038/s41598-020-71528-3 |
| Web of Science KeyUT | 000570970200006 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-020-71528-3 |
| JaLCDOI | 10.18926/AMO/60368 |
|---|---|
| FullText URL | 74_4_301.pdf |
| Author | Takahashi, Kei| Kitamura, Yoshihisa| Ushio, Soichiro| Sendo, Toshiaki| |
| Abstract | Ketamine has been clinically proven to ameliorate depression, including treatment-resistant depression. The detailed mechanism of action of ketamine in treatment-resistant depression remains unclear. We examined the effects of ketamine on the immobility times of adrenocorticotropic hormone (ACTH)-treated rats during the forced swim test, and we explored the mechanism by which ketamine acts in this model. We investigated the neuroanatomical site of action by microinjecting ketamine into the medial prefrontal cortex of rats. A significant reduction of the rats’ immobility during the forced swim test was observed after the intraperitoneal injection of ketamine in both saline- and ACTH-treated rats. The microinjection of ketamine into the medial prefrontal cortex also decreased immobility during the forced swim test in both saline- and ACTH-treated rats. The immobility-decreasing effect of intraperitoneally injected ketamine was blocked by administering WAY100635, a 5-HT1A receptor antagonist, into the medial prefrontal cortex. These findings contribute to the evidence that ketamine can be useful against treatment-resistant depressive conditions. The immobility-reducing effects of ketamine might be mediated by 5-HT1A receptor activity in the medial prefrontal cortex. |
| Keywords | ketamine adrenocorticotropic hormone forced swim test medial prefrontal cortex 5-HT1A receptor |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-08 |
| Volume | volume74 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 301 |
| End Page | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32843761 |
| Web of Science KeyUT | 000562508700005 |
| NAID | 120006880207 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakamura, Shunsuke| Matsuno, Aya| Ueda, Masashi| |
| Keywords | αvβ6 integrin Pancreatic ductal adenocarcinoma (PDAC) A20FMDV2 Aspartic acids Electric charge |
| Note | This is a post-peer-review, pre-copyedit version of an article published in Annals of Nuclear Medicine. The final authenticated version is available online at: http://dx.doi.org/10.1007/s12149-020-01483-6.| |
| Published Date | 2020-06-08 |
| Publication Title | Annals of Nuclear Medicine |
| Volume | volume34 |
| Publisher | Springer |
| Start Page | 575 |
| End Page | 582 |
| ISSN | 0914-7187 |
| NCID | AA10708017 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 32514725 |
| DOI | 10.1007/s12149-020-01483-6 |
| Web of Science KeyUT | 000539348100001 |
| Related Url | isVersionOf https://doi.org/10.1007/s12149-020-01483-6 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | El-Saied, Fathy| El-Aarag, Bishoy| Salem, Tarek| Said, Ghada| Khalifa, Shaden A. M.| El-Seedi, Hesham R.| |
| Keywords | metal complexes isatin-N(4)antipyrinethiosemicarbazone Ehrlich ascites carcinoma tumor volume VEGF caspase-7 |
| Published Date | 2019-09-11 |
| Publication Title | Molecules |
| Volume | volume24 |
| Issue | issue18 |
| Publisher | MDPI |
| ISSN | 1420-3049 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31514445 |
| DOI | 10.3390/molecules24183313 |
| Web of Science KeyUT | 000488830500105 |
| Related Url | isVersionOf https://doi.org/10.3390/molecules24183313 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | El-Aarag, Bishoy| Khairy, Asmaa| Khalifa, Shaden A. M.| El-Seedi, Hesham R.| |
| Keywords | liver injury CCl4 Tamarix aphylla oxidative stress apoptosis angiogenesis |
| Published Date | 2019-10-21 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume20 |
| Issue | issue20 |
| Publisher | MDPI |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31640181 |
| DOI | 10.3390/ijms20205215 |
| Web of Science KeyUT | 000498822800247 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms20205215 |
| FullText URL | MIB21_3_519.pdf |
|---|---|
| Author | Matsuura, Yuki| Ueda, Masashi| Higaki, Yusuke| Sano, Kohei| Saji, Hideo| Enomoto, Shuichi| |
| Keywords | Alzheimer's disease Nicotinic acetylcholine receptors 2-Deoxy-2-[F-18]fluoro-D-glucose ([F-18]FDG) 5-[I-123]Iodo-3-[2(S)-azetidinylmethoxy]pyridine ([I-123]5IA) APP PS2 mice |
| Published Date | 2018-07-25 |
| Publication Title | Molecular Imaging and Biology |
| Volume | volume21 |
| Issue | issue3 |
| Publisher | Springer |
| Start Page | 519 |
| End Page | 528 |
| ISSN | 1536-1632 |
| NCID | AA1170000X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30047036 |
| DOI | 10.1007/s11307-018-1253-4 |
| Web of Science KeyUT | 000468363800015 |
| Related Url | isVersionOf https://doi.org/10.1007/s11307-018-1253-4 |
| FullText URL | Biomed_Pharmacother_2019109038.pdf |
|---|---|
| Author | Ueno, Hiroshi| Suemitsu, Shunsuke| Murakami, Shinji| Kitamura, Naoya| Wani, Kenta| Takahashi, Yu| Matsumoto, Yosuke| Okamoto, Motoi| Ishihara, Takeshi| |
| Keywords | Inhalation Dizocilpine MK-801 Mouse Drug Schizophrenia |
| Published Date | 2019-09-30 |
| Publication Title | Biomedicine & Pharmacotherapy |
| Volume | volume117 |
| Publisher | Elsevier |
| Start Page | 109038 |
| ISSN | 07533322 |
| NCID | AA10506249 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Authors. Published by Elsevier Masson SAS. |
| File Version | publisher |
| PubMed ID | 31177060 |
| DOI | 10.1016/j.biopha.2019.109038 |
| Web of Science KeyUT | 000477804500018 |
| Related Url | isVersionOf https://doi.org/10.1016/j.biopha.2019.109038 |
| JaLCDOI | 10.18926/AMO/56860 |
|---|---|
| FullText URL | 73_3_189.pdf |
| Author | Sakamoto, Shinji| Kawai, Hiroki| Okahisa, Yuko| Tsutsui, Ko| Kanbayashi, Takashi| Tanaka, Keiko| Mizuki, Yutaka| Takaki, Manabu| Yamada, Norihito| |
| Abstract | Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti-NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry. |
| Keywords | NMDAR encephalitis psychiatric symptom schizophrenia mood disorder |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-06 |
| Volume | volume73 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 189 |
| End Page | 195 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31235965 |
