検索結果 - 岡山大学学術成果リポジトリ

Integration of QSAR modeling and in vitro validation for identification of food-derived Nrf2 activators against arsenic-induced toxicity

フルテキストURL	fulltext.pdf
著者	Huong, Ngo Thanh\| Kodama, Susumu\| Ono, Atsushi\|
キーワード	Arsenic toxicity Nrf2 activator QSAR modeling Food-derived compounds In vitro
発行日	2026
出版物タイトル	The Journal of Toxicological Sciences
巻	51巻
号	10号
出版者	Japanese Society of Toxicology
開始ページ	533
終了ページ	547
ISSN	0388-1350
NCID	AN00002808
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2026 Author(s)
論文のバージョン	publisher
PubMed ID	42816373
DOI	10.2131/jts.51.533
CRID	1390309758326043520
関連URL	isVersionOf https://doi.org/10.2131/jts.51.533

Regional Prevalence of Carbapenemase-Producing Enterobacterales and Extended-Spectrum Beta-Lactamase-Producing Enterobacterales in Okayama and Neighboring Prefectures, Japan

JaLCDOI	10.18926/AMO/71066
フルテキストURL	80_4_233.pdf
著者	Ogawa, Sakura\| Fukushima, Shinnosuke\| Akazawa, Hidemasa\| Namba, Sachie\| Hirota, Chiyoko\| Kishiue, Tomoyoshi\| Ibara, Shohei\| Kondo, Takayuki\| Fukuda, Genshi\| Iio, Koji\| Tsuji, Shuma\| Gotoh, Kazuyoshi\| Otsuka, Fumio\| Hagiya, Hideharu\|
抄録	Carbapenemase-producing Enterobacterales (CPE) and extended-spectrum β-lactamase (ESBL)-producing Enterobacterales (ESBL-E) are representative antimicrobial-resistant pathogens. We investigated the prevalence of CPE and ESBL-E in Okayama, Japan to clarify their current epidemiology and potential clinical burden. Active surveillance for CPE and ESBL-E was performed first, using stool samples submitted to the Okayama Medical Laboratory (Japan) in the years 2024-2025. Screening was performed using a selective agar (CHROMagar mSuper CARBA/ESBL). Phenotypic identification was conducted with the use of a modified carbapenem inactivation method and double-disk phenotypic confirmatory tests. Clinical information including patient age, sex, sampling date, and hospital address were collected, and the data were analyzed according to specimen origin (hospitals, clinics, and health checkups). A total of 2,000 stool samples were screened, of which two CPE isolates (0.1%) and 285 ESBL-E isolates (14.3%) were identified. By specimen origin, the ESBL-E positivity rate was significantly higher in hospitals (17.4%) than in clinics (11.8%). By age category, the late elderly (> 75 years) exhibited the highest ESBL-E positivity rate (22.6%) compared to other age groups. In the clinics and health checkups, infants (0 years) demonstrated high ESBL-E positivity rates (18.2% and 14.3%, respectively). Escherichia coli was the most common ESBL-E organism in the hospitals (77.2%), clinics (88.8%), and health checkups (87.5%). Our active screening demonstrated that the prevalences of CPE and ESBL-E were within the reported ranges; however, in this era of increasing internationalization, continuous surveillance of these notifiable pathogens is warranted.
キーワード	antimicrobial resistance carbapenem-resistant Enterobacteriaceae extended-spectrum β-lactamase infection prevention and control Okayama Medical Laboratory
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2026-08
巻	80巻
号	4号
出版者	Okayama University Medical School
開始ページ	233
終了ページ	240
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
レファレンス	Jean SS, Harnod D and Hsueh PR: Global threat of carbapenem-resistant Gram-negative bacteria. Front Cell Infect Microbiol (2022) 12: 823684.\| Baek MS, Kim JH, Park JH, Kim TW, Jung HI and Kwon YS: Comparison of mortality rates in patients with carbapenem-resistant Enterobacterales bacteremia according to carbapenemase production: a multicenter propensity-score matched study. Sci Rep (2024) 14: 597.\| Takei K, Ogawa M, Sakata R and Kanamori H: Epidemiological characteristics of carbapenem-resistant Enterobacterales in Japan: a nationwide analysis of data from a clinical laboratory center (2016-2022). Pathogens (2023) 12: 1246.\| Yamamoto N, Asada R, Kawahara R, Hagiya H, Akeda Y and Shanmugakani RK: Prevalence of, and risk factors for, carriage of carbapenem-resistant Enterobacteriaceae among hospitalized patients in Japan. J Hosp Infect (2017) 97: 212-217.\| Hagiya H, Yamamoto N, Kawahara R, Akeda Y, Shanmugakani RK and Ueda A: Risk factors for fecal carriage of IMP-6-producing Enterobacteriaceae at a long-term care hospital in Japan: a follow-up report from the northern Osaka multicentre study group. J Infect Chemother (2018) 24: 769-772.\| Ohno Y, Nakamura A, Hashimoto E, Noguchi N, Matsumoto G and Fukuda S: Fecal carriage and molecular epidemiologic characteristics of carbapenemase-producing Enterobacterales in a primary care hospital in a Japanese city. J Infect Chemother (2020) 26: 928-932.\| Ishii Y, Aoki K, Tateda K and Kiyota H: Multicenter collaboration study on the β-lactam-resistant Enterobacteriaceae in Japan ‒ the 65th anniversary public interest purpose project of the Japanese Society of Chemotherapy. J Infect Chemother (2017) 23: 583-586.\| Nakai M, Oka K, Watanabe G, Kamei K, Tsukada N and Mori R: Epidemiology and molecular characterization of fecal carriage of third-generation cephalosporin-resistant Enterobacterales among elderly residents in Japan. J Infect Chemother (2022) 28: 569-575.\| Hagiya H, Onishi Y, Shinohara N, Tokuyasu M, Imanishi A and Fukushima S: High frequency of extended-spectrum beta-lactamase-producing Enterobacteriaceae carriers at a Japanese long-term care hospital. J Infect Chemother (2022) 28: 1578-1581.\| Fukushima S, Hagiya H, Uda K, Gotoh K and Otsuka F: Current prevalence of antimicrobial resistance in Okayama from a national database between 2018 and 2021. Acta Med Okayama (2023) 77: 255-262.\| Fukushima S, Hagiya H, Gotoh K, Tsuji S, Iio K and Matsushita O: Detection of imported clinical strain of blaNDM-1-harbouring ST147 Klebsiella pneumoniae from a Ukrainian immigrant. J Travel Med (2024) 31: taae011.\| Gotoh K, Hagiya H, Iio K, Yamada H, Matsushita O and Otsuka F: Detection of Enterobacter cloacae complex strain with a blaNDM-1-harboring plasmid from an elderly resident at a long-term care facility in Okayama, Japan. J Infect Chemother (2022) 28: 1697-1699.\| Gotoh K, Miyoshi M, I Putu Bayu Mayura, Tsuji S, Iio K and Fukushima S: Phenotypic and genetic characteristics of carbapenemase-producing Enterobacterales isolates at Okayama University Hospital. Acta Med Okayama (2024) 78: 371-376.\| Pierce VM, Simner PJ, Lonsway DR, Roe-Carpenter DE, Johnson JK and Brasso WB: Modified carbapenem inactivation method for phenotypic detection of carbapenemase production among Enterobacteriaceae. J Clin Microbiol (2017) 55: 2321-2333.\| Kanda Y: Investigation of the freely available easy-to-use software “EZR” for medical statistics. Bone Marrow Transplant (2013) 48: 452-458.\| Bezabih YM, Bezabih A, Dion M, Batard E, Teka S and Obole A: Comparison of the global prevalence and trend of human intestinal carriage of ESBL-producing Escherichia coli between healthcare and community settings: a systematic review and meta-analysis. JAC Antimicrob Resist (2022) 4: dlac048.\| Ng RWY, Yang L, Lau SH, Hawkey P and Ip M: Global prevalence of human intestinal carriage of ESBL-producing Escherichia coli during and after the COVID-19 pandemic. JAC Antimicrob Resist (2025) 7: dlaf001.\| Raffelsberger N, Buczek DJ, Svendsen K, Småbrekke L, Pöntinen AK and Löhr IH: Community carriage of ESBL-producing Escherichia coli and Klebsiella pneumoniae: a cross-sectional study of risk factors and comparative genomics of carriage and clinical isolates. mSphere (2023) 8: e00025-23.\| Islam K, Heffernan AJ, Naicker S, Henderson A, Chowdhury MAH and Roberts JA: Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing Escherichia coli in South Asia. Future Microbiol (2021) 16: 521-535.\| Rahaman A, Mimi A, Antor MTH, Bakhtiyar Z, Hasan MAE and Fahim NAI: Prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated from animals in Bangladesh: a systematic review and meta-analysis. One Health (2025) 21: 101237.\| Xie Y, Srivastava IM, Jing F, Ma C, Wu X, Chen Y, Du Y, Low XYC, Ping Y, Pan J, Gupta A, Graves N and Mo Y: One Health perspective of antibiotic resistance in Enterobacterales from Southeast Asia: a systematic review and meta-analysis. Res Sq (2025) 16: 1694.\| Jia P, Zhu Y, Li X, Kudinha T, Yang Y and Zhang G: High prevalence of extended-spectrum beta-lactamases in Escherichia coli strains collected from strictly defined community-acquired urinary tract infections in adults in China: a multicenter prospective clinical microbiological and molecular study. Front Microbiol (2021) 12: 663033.\| Chao CM, Lai CC and Yu WL: Epidemiology of extended-spectrum β-lactamases in Enterobacterales in Taiwan for over two decades. Front Microbiol (2022) 13: 1060050.\| Chaisaeng S, Chopjitt P, Kasemsiri P, Putthanachote N, Boueroy P and Takeuchi D: High prevalence of ESBL-producing Escherichia coli phylogroup B2 clinical isolates in northeastern Thailand. BMC Microbiol (2024) 24: 425.\| Sawatwong P, Sapchookul P, Whistler T, Gregory CJ, Sangwichian O and Makprasert S: High burden of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae bacteremia in older adults: a seven-year study in two rural Thai provinces. Am J Trop Med Hyg (2019) 100: 943-951.\| Sunarno S, Puspandari N, Fitriana F, Nikmah UA, Idrus HH and Panjaitan NSD: Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Indonesia and Southeast Asian countries: GLASS data 2018. AIMS Microbiol (2023) 9: 218-227.\| Kawamura K, Nagano N, Suzuki M, Wachino JI, Kimura K and Arakawa Y: ESBL-producing Escherichia coli and its rapid rise among healthy people. Food Saf (2017) 5: 122-150.\| Shibuki R, Nishiyama M, Mori M, Baba H, Kanamori H and Watanabe T: Characterization of extended-spectrum β-lactamase-producing Escherichia coli isolated from municipal and hospital wastewater in Japan. J Glob Antimicrob Resist (2023) 32: 145-151.\| Kawata S, Morimoto S, Kosai K, Kawamoto Y, Nakashima Y and Morinaga Y: The fecal carriage rate of extended-spectrum β-lactamase-producing or carbapenem-resistant Enterobacterales among Japanese infants in the community at the 4-month health examination in a rural city. Front Cell Infect Microbiol (2023) 13: 1168451.\|

Burden of Lower Urinary Tract and Genital Symptoms in Young Transgender Men: Prevalence and Impact on Daily Life

フルテキストURL	fulltext.pdf
著者	Kobayashi, Tomoko\| Moriwake, Takatoshi\| Tominaga, Yusuke\| Ozaki, Nariaki\| Horii, Satoshi\| Tsuboi, Ichiro\| Yoshinaga, Kasumi\| Yamanoi, Tomoaki\| Kawada, Tatsushi\| Sadahira, Takuya\| Iwata, Takehiro\| Katayama, Satoshi\| Nishimura, Shingo\| Bekku, Kensuke\| Matsumoto, Yuko\| Inoue, Miyabi\| Watanabe, Masami\| Ishii, Ayano\| Watanabe, Toyohiko\| Araki, Motoo\|
キーワード	lower urinary tract symptoms transgender men urinary-related activity restriction vaginal symptoms
発行日	2026-07-31
出版物タイトル	International Journal of Urology
巻	33巻
号	8号
出版者	Wiley
開始ページ	e70553
ISSN	0919-8172
NCID	AA11042471
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2026 The Author(s).
論文のバージョン	publisher
PubMed ID	42533767
DOI	10.1111/iju.70553
Web of Science KeyUT	001836647400001
関連URL	isVersionOf https://doi.org/10.1111/iju.70553

Early administration of renin–angiotensin system inhibitors improves survival and cardiac remodeling in heart failure with preserved ejection fraction

フルテキストURL	fulltext.pdf
著者	Kono, Yuka\| Sonoda, Kunihiro\| Ohtake, Kazuo\| Ota, Akinobu\| Yamamoto, Shusei\| Nakayama, Hinako\| Fukuoka, Taketo\| Kawai, Yuki\| Tago, Haruka\| Watanabe, Nobuhisa\| Sato, Ikumi\| Hirohata, Satoshi\| Kitamori, Kazuya\| Watanabe, Shogo\|
発行日	2026-03-12
出版物タイトル	PLOS One
巻	21巻
号	3号
出版者	Public Library of Science (PLoS)
開始ページ	e0339600
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2026 Kono et al.
論文のバージョン	publisher
PubMed ID	41818254
DOI	10.1371/journal.pone.0339600
Web of Science KeyUT	001712928100024
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0339600

TeMPRA: advancing continuing professional development in pediatric rheumatology in Japan

フルテキストURL	fulltext.pdf
著者	Wakiguchi, Hiroyuki\| Hashimoto, Kunio\| Yashiro, Masato\| Nishimura, Kenichi\| Ebato, Takasuke\| Akamine, Keiji\| Uejima, Yoji\| Sato, Tomomi\| Yamasaki, Yuichi\| Yasumura, Junko\| Okazaki, Fumiko\| Kizawa, Toshitaka\| Yasuoka, Ryuhei\| Ishikawa, Tomoaki\| Yamamoto, Takeshi\| Fujita, Yuji\| Itoh, Naohiro\| Takasaki, Asami\| Sakurai, Nodoka\| Suzuki, Kazuo\| Tamai, Tasuku\| Hirano, Naoki\| Okamoto, Nami\| Shimizu, Masaki\|
キーワード	Child Education Juvenile idiopathic arthritis Practice Rheumatic diseases Systemic lupus erythematosus Team of mid-career pediatric rheumatologists alliance
発行日	2026-01-24
出版物タイトル	Pediatric Rheumatology
巻	24巻
号	1号
出版者	Springer Science and Business Media LLC
ISSN	1546-0096
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
PubMed ID	41580803
DOI	10.1186/s12969-025-01182-4
Web of Science KeyUT	001693782300001
関連URL	isVersionOf https://doi.org/10.1186/s12969-025-01182-4

Development of a Stroke Discharge Support Evaluation Scale for Ward Nurses in Acute Care Hospitals

JaLCDOI	10.18926/AMO/70069
フルテキストURL	80_1_017.pdf
著者	Yano, Hideki\| Takahata, Yoko\| Yamaguchi, Takeshi\| Saito, Shinya\|
抄録	This study aimed to develop a scale enabling nurses to objectively evaluate their own stroke discharge support, as a basis for enhancing its overall effectiveness. A draft scale was created based on a literature review, and consisted of a 51-item, 5-point Likert-type questionnaire administered to ward nurses engaged in stroke discharge support at acute care hospitals. Factor analysis was performed to refine the scale. Construct validity was assessed using the known-groups method, and reliability was evaluated through internal consistency analysis. The resulting Stroke Discharge Support Evaluation Scale comprises 29 items across 5 factors, each rated on a 5-point Likert scale. Analysis of the data collected from 237 valid responses demonstrated good internal consistency and supported the scale’s construct validity. The Stroke Discharge Support Evaluation Scale is a reliable and valid tool enabling ward nurses in acute care hospitals to evaluate their own stroke discharge support.
キーワード	stroke discharge support scale development
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2026-02
巻	80巻
号	1号
出版者	Okayama University Medical School
開始ページ	17
終了ページ	30
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	41748146
Web of Science KeyUT	001712994500003

A Novel Nomogram that Predicts Chronic Hemodialysis Patients’ Survival Based on Their Sedentary Behavior

JaLCDOI	10.18926/AMO/70068
フルテキストURL	80_1_009.pdf
著者	Sugahara, Kentaro\| Kondo, Takashi\| Miyatake, Nobuyuki\| Nishi, Hiroyuki\| Ujike, Kazuhiro\| Koumoto, Kiichi\| Namio, Keiichi\| Hishii, Shuhei\| Katayama, Akihiko\| Suzuki, Hiromi\| Yamamoto, Yorimasa\|
抄録	Appropriate treatments for chronic hemodialysis patients are a public health challenge in Japan. Sedentary behavior appears to be closely associated with these patients’ survival. We thus sought to develop a nomogram that predicts survival based on the duration of chronic hemodialysis patients’ sedentary behavior. One hundred twenty-four patients under chronic hemodialysis (73 men, 51 women, age 71.7±11.1 years) were enrolled in this cohort study. The patients wore a triaxial accelerometer that measured both their sedentary behavior, i.e., total sedentary behavior (minutes) and their maximum sedentary bouts (min) on non-hemodialysis days. We obtained the Kaplan-Meier curve and used the log-rank test and a Cox proportional hazards model to evaluate the relationship between the patients’ sedentary behavior and their survival. We also used a Cox proportional hazards model to develop a nomogram for the patients’ 5-year survival rate. Forty-six patients died during the follow-up period. When we stratified the patients by the medians of total sedentary behavior and maximum sedentary bouts, we observed significant between-group differences. After adjustment for confounding factors in a Cox proportional hazards model, total sedentary behavior and maximum sedentary bouts were identified as critical survival factors, and we generated a nomogram using an index of sedentary behavior. Our analysis results demonstrated that sedentary behavior on non-dialysis days was closely associated with the survival of the chronic hemodialysis patients, suggesting that a decrease in sedentary behavior would prolong their survival. The nomogram developed herein based on sedentary behavior may be useful for predicting the outcomes of chronic hemodialysis patients.
キーワード	nomogram chronic hemodialysis sedentary behavior Cox proportional hazards model Kaplan- Meier curve
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2026-02
巻	80巻
号	1号
出版者	Okayama University Medical School
開始ページ	9
終了ページ	16
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	41748145
Web of Science KeyUT	001712994500002

フルテキストURL	fulltext.pdf
著者	Takeuchi, Noriko\| Maruyama, Takayuki\| Toyama, Naoki\| Katsube, Yuzuki\| Tabuchi, Takahiro\| Ekuni, Daisuke\|
キーワード	oral health-related quality of life depression status cohort study
発行日	2026-01-04
出版物タイトル	Journal of Clinical Medicine
巻	15巻
号	1号
出版者	MDPI AG
開始ページ	376
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2026 by the authors.
論文のバージョン	publisher
DOI	10.3390/jcm15010376
関連URL	isVersionOf https://doi.org/10.3390/jcm15010376

Activation of the pentose phosphate pathway by microcurrent stimulation mediates antioxidant effects in inflammation-stimulated macrophages

フルテキストURL	fulltext.pdf
著者	Uemura, Mikiko\| Maeshige, Noriaki\| Yamaguchi, Atomu\| Ma, Xiaoqi\| Fu, Yunfei\| Inoue, Taketo\| Matsuda, Mami\| Nishimura, Yuya\| Hasunuma, Tomohisa\| Wang, Ji\| Kondo, Hiroyo\| Fujino, Hidemi\|
キーワード	microcurrent stimulation pentose phosphate pathway (PPP) NADPH oxidative stress macrophage glucose metabolism
発行日	2025-11-14
出版物タイトル	Frontiers in Physiology
巻	16巻
出版者	Frontiers Media SA
開始ページ	1666999
ISSN	1664-042X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Uemura, Maeshige, Yamaguchi, Ma, Fu, Inoue, Matsuda, Nishimura, Hasunuma, Wang, Kondo and Fujino.
論文のバージョン	publisher
PubMed ID	41321495
DOI	10.3389/fphys.2025.1666999
Web of Science KeyUT	001625379800001
関連URL	isVersionOf https://doi.org/10.3389/fphys.2025.1666999

Effects of Thoron Inhalation and Cyclosporin A Treatment on Dextran Sulfate Sodium-Induced Oxidative Damage in Mice

JaLCDOI	10.18926/AMO/69844
フルテキストURL	79_6_421.pdf
著者	Tanaka, Ayumi\| Naoe, Shota\| Takenaka, Reiju\| Kanzaki, Norie\| Sakoda, Akihiro\| Yamaoka, Kiyonori\| Kataoka, Takahiro\|
抄録	Radon (222Rn; Rn) and thoron (220Rn; Tn) inhalation have been reported to enhance antioxidant activity in various organs. However, the effects of Tn on the colon have not been investigated. This study aimed to clarify the effects of Tn inhalation, alone and in combination with cyclosporin A (CsA), on dextran sulfate sodium (DSS)-induced colitis, and the accompanying oxidative stress, in mice. Male BALB/c mice were subjected to continuous 8-day Tn inhalation (c-Tn, 533±128 Bq/m3) or alternate-day Tn inhalation over the same period (f-Tn, 577±63Bq/m3), followed by treatment with 3% DSS and either CsA or vehicle for 7 days. Although the disease activity index (DAI) decreased significantly by day 2 in the c-Tn group, scores remained significantly higher than those in the f-Tn group. In the c-Tn group, superoxide dismutase and catalase activity in the colon were significantly elevated compared with those in sham controls. Thus, DSS-induced damage was effectively inhibited in the earlier stages by the c-Tn mode of inhalation than by the f-Tn mode. These findings suggest that continuous Tn inhalation more effectively attenuated early colitis symptoms than alternate-day inhalation, potentially through upregulation of antioxidant defenses. Tn and CsA showed no combined effects.
キーワード	thoron DSS antioxidant activity CsA colon
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-12
巻	79巻
号	6号
出版者	Okayama University Medical School
開始ページ	421
終了ページ	429
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	41443803
Web of Science KeyUT	001674277500003

The Short‐Term Impacts of Japan's 2024 Physician Working‐Hour Limits on Labor Conditions, Self‐Directed Professional Development, and Happiness Among Obstetrician‐Gynecologists

フルテキストURL	fulltext.pdf
著者	Maeda, Yuto\| Nakagawa, Satoru\| Nakanishi, Kentaro\| Inoue, Eri\| Inoue, Daisuke\| Kido, Saki\| Kido, Michiko\| Koga, Kaori\| Suzuki, Shunji\| Suzuki, Yukio\| Haraga, Junko\| Masuyama, Hisashi\| Yamamoto, Eiko\| Umazume, Takeshi\| Yokoyama, Yoshihito\| Iwase, Akira\| Ikeda, Tomoaki\| Yoshida, Yoshio\| Kudo, Yoshiki\| Sugiyama, Takashi\| Miura, Kiyonori\| Yahata, Hideaki\| Unno, Nobuya\| Kurasawa, Kentaro\| Maenaka, Takahide\| Miyagi, Etsuko\| Kato, Kiyoko\| Kato, Yasuhito\|
キーワード	gynecologists happiness obstetrician work style reform working-hour limits
発行日	2025-11
出版物タイトル	Journal of Obstetrics and Gynaecology Research
巻	51巻
号	11号
出版者	Wiley
開始ページ	e70112
ISSN	1341-8076
NCID	AA11082002
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	41290213
DOI	10.1111/jog.70112
Web of Science KeyUT	001627003400005
関連URL	isVersionOf https://doi.org/10.1111/jog.70112

AHA’s Life’s Essential-8 cardiovascular health metrics and progression of coronary artery calcification in Japanese men

フルテキストURL	fulltext.pdf
著者	Mondal, Rajib\| Kadota, Aya\| Yano, Yuichiro\| Kadowaki, Sayaka\| Torii, Sayuki\| Kondo, Keiko\| Harada, Akiko\| Kawashima, Megumi\| Miyazawa, Itsuko\| Segawa, Hiroyoshi\| Hisamatsu, Takashi\| Watanabe, Yoshiyuki\| Nakagawa, Yoshihisa\| Fujiyoshi, Akira\| Miura, Katsuyuki\|
キーワード	Life’s essential-8 Cardiovascular health metrics Subclinical atherosclerosis Coronary artery calcification CAC progression
発行日	2025-09
出版物タイトル	American Journal of Preventive Cardiology
巻	23巻
出版者	Elsevier BV
開始ページ	101081
ISSN	2666-6677
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Authors.
論文のバージョン	publisher
PubMed ID	40894317
DOI	10.1016/j.ajpc.2025.101081
Web of Science KeyUT	001561185100001
関連URL	isVersionOf https://doi.org/10.1016/j.ajpc.2025.101081

Introduction to the “Japanese and Western approaches to psychotrauma” symposium

フルテキストURL	fulltext.pdf
著者	Nagamine, Masanori\| Nakao, Tomoyo\| van Bergen, Leo\| Shigemura, Jun\| Saito, Taku\| van der Does, Florentine H.S.\| Kitano, Masato\| Giltay, Erik J.\| van der Wee, Nic J.\| Vermetten, Eric\|
キーワード	Psychotrauma World War II Japan Europe KZ syndrome Post-traumatic stress disorder
発行日	2025-06
出版物タイトル	Asian Journal of Psychiatry
巻	108巻
出版者	Elsevier BV
開始ページ	104508
ISSN	1876-2018
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Authors.
論文のバージョン	publisher
PubMed ID	40287989
DOI	10.1016/j.ajp.2025.104508
Web of Science KeyUT	001482303000001
関連URL	isVersionOf https://doi.org/10.1016/j.ajp.2025.104508

Blood Pressure and Heart Rate Patterns Identified by Unsupervised Machine Learning and Their Associations with Subclinical Cerebral and Renal Damage in a Japanese Community: The Masuda Study

JaLCDOI	10.18926/AMO/69438
フルテキストURL	79_5_369.pdf
著者	Hisamatsu, Takashi\| Kinuta, Minako\| Munetomo, Sosuke\| Fukuda, Mari\| Kojima, Katsuhide\| Taniguchi, Kaori\| Nakahata, Noriko\| Kanda, Hideyuki\|
抄録	We applied unsupervised machine learning to analyze blood pressure (BP) and resting heart rate (HR) patterns measured during a 1-year period to assess their cross-sectional relationships with subclinical cerebral and renal target damage. Dimension reduction via uniform manifold approximation and projection, followed by K-means++ clustering, was used to categorize 362 community-dwelling participants (mean age, 56.2 years; 54.9% women) into three groups: Low BP and Low HR (Lo-BP/Lo-HR), High BP and High HR (Hi-BP/Hi-HR), and Low BP and High HR (Lo-BP/Hi-HR). Cerebral vessel lesions were defined as the presence of at least one of the following magnetic resonance imaging findings: lacunar infarcts, white matter hyperintensities, cerebral microbleeds, or intracranial artery stenosis. A high urinary albumin-to-creatinine ratio (UACR) was defined as the top 10% (≥ 12 mg/g) of the mean value from ≥2 measurements. Poisson regression with robust error variance, adjusted for demographics, lifestyle, and medical history, showed that the Hi-BP/Hi-HR group had relative risks of 3.62 (95% confidence interval, 1.75-7.46) for cerebral vessel lesions and 3.58 (1.33-9.67) for high UACR, and the Lo-BP/Hi-HR group had a relative risk of 3.09 (1.12-8.57) for high UACR, compared with the Lo-BP/Lo-HR group. These findings demonstrate the utility of an unsupervised, data-driven approach for identifying physiological patterns associated with subclinical target organ damage.
キーワード	blood pressure heart rate subclinical disease uniform manifold approximation and projection unsupervised machine learning
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-10
巻	79巻
号	5号
出版者	Okayama University Medical School
開始ページ	369
終了ページ	379
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	41126468
Web of Science KeyUT	001606013200007

Activated Clotting Time Requires Adaptation Across Altered Measurement Devices: Determination of Appropriate Range During Atrial Fibrillation Ablation

フルテキストURL	fulltext.pdf
著者	Sakanoue, Haruna\| Yamaji, Hirosuke\| Okamoto, Sayaka\| Okano, Kumi\| Fujita, Yuka\| Higashiya, Shunichi\| Murakami, Takashi\| Hirohata, Satoshi\| Kusachi, Shozo\|
キーワード	anticoagulation heparin catheter supraventricular arrhythmia point-of-care testing
発行日	2025-03
出版物タイトル	Clinical and Applied Thrombosis/Hemostasis
巻	31巻
出版者	SAGE Publications
ISSN	1076-0296
NCID	AA11016631
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	40156227
DOI	10.1177/10760296251332938
Web of Science KeyUT	001456050100001
関連URL	isVersionOf https://doi.org/10.1177/10760296251332938

The Work Productivity of Cancer-survivor and Non-cancer-survivor Workers

JaLCDOI	10.18926/AMO/69149
フルテキストURL	79_4_243.pdf
著者	Kamano, Mika\| Kanda, Kanae\| Ngatu, Nlandu Roger\| Murakami, Akitsu\| Yamadori, Yusuke\| Hirao, Tomohiro\|
抄録	We investigated the work productivity levels of employed cancer survivors and non-cancer-survivor workers by conducting a cross-sectional study in Japan between February and March 2019, using an online survey. A total of 561 employed individuals aged 20-64 years were analyzed. Work productivity was assessed using the Work Productivity and Activity Impairment-General Health questionnaire which evaluates absenteeism, presenteeism, and overall work productivity loss. The questionnaire responses demonstrated that the cancer survivors within 1 year of diagnosis had significantly higher absenteeism compared to the non-cancer workers (p=0.048). Although presenteeism and overall work productivity loss were also higher in the non-cancer-survivor group, the differences were not significant. Cancer survivors within 1 year of diagnosis exhibited higher absenteeism, but their work productivity appeared to recover to levels comparable to those of the non-cancer workers over time. These findings may contribute to workplace policies supporting cancer survivors’ return to work.
キーワード	cancer survivor work productivity absenteeism presenteeism
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-08
巻	79巻
号	4号
出版者	Okayama University Medical School
開始ページ	243
終了ページ	251
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40859440
Web of Science KeyUT	001566286400003

A Preliminary Survey of Rheumatologists on the Management of Late-onset Rheumatoid Arthritis in Japan

フルテキストURL	fulltext.pdf suppl1.tif suppl2.pdf suppl3.pdf
著者	Takanashi, Satoshi\| Kaneko, Yuko\| Kawahito, Yutaka\| Kida, Takashi\| Sugihara, Takahiko\| Kojima, Toshihisa\| Harada, Ryozo\| Ishitoku, Michinori\| Hirata, Shintaro\| Hashimoto, Motomu\| Hidaka, Toshihiko\| Abe, Asami\| Ishikawa, Hajime\| Ito, Hiromu\| Kishimoto, Mitsumasa\| Matsui, Kazuo\| Matsui, Toshihiro\| Matsushita, Isao\| Onishi, Akira\| Morinobu, Akio\| Nishida, Keiichiro\| Asai, Shuji\| Tanaka, Eiichi\| Harigai, Masayoshi\| Kojima, Masayo\|
キーワード	late-onset rheumatoid arthritis ageing society questionnaire
発行日	2024-12-15
出版物タイトル	Internal Medicine
巻	63巻
号	24号
出版者	Japanese Society of Internal Medicine
開始ページ	3299
終了ページ	3306
ISSN	0918-2918
NCID	AA10827774
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by The Japanese Society of Internal Medicine
論文のバージョン	publisher
PubMed ID	38692915
DOI	10.2169/internalmedicine.3288-23
CRID	1390021072388391552
Web of Science KeyUT	001388887300002
関連URL	isVersionOf https://doi.org/10.2169/internalmedicine.3288-23

Effects of Palliative Surgical Treatment for Spinal Metastases on the Patient’s Quality of Life With a Focus on the Segment of the Metastasis: A Prospective Multicenter Study

フルテキストURL	fulltext.pdf
著者	Segi, Naoki\| Nakashima, Hiroaki\| Ito, Sadayuki\| Ouchida, Jun\| Shiratani, Yuki\| Shimizu, Takaki\| Suzuki, Akinobu\| Terai, Hidetomi\| Kakutani, Kenichiro\| Kanda, Yutaro\| Tominaga, Hiroyuki\| Kawamura, Ichiro\| Ishihara, Masayuki\| Paku, Masaaki\| Takahashi, Yohei\| Funaba, Masahiro\| Funayama, Toru\| Nakajima, Hideaki\| Akeda, Koji\| Hirai, Takashi\| Inoue, Hirokazu\| Nakanishi, Kazuo\| Funao, Haruki\| Oshigiri, Tsutomu\| Otsuki, Bungo\| Kobayakawa, Kazu\| Tanishima, Shinji\| Hashimoto, Ko\| Iimura, Takuya\| Sawada, Hirokatsu\| Uotani, Koji\| Manabe, Hiroaki\| Iwai, Chizuo\| Yamabe, Daisuke\| Hiyama, Akihiko\| Seki, Shoji\| Goto, Yuta\| Miyazaki, Masashi\| Watanabe, Kazuyuki\| Nakamae, Toshio\| Kaito, Takashi\| Nagoshi, Narihito\| Kato, Satoshi\| Watanabe, Kota\| Imagama, Shiro\| Inoue, Gen\| Furuya, Takeo\|
キーワード	spinal metastasis metastasis segment palliative surgery quality of life activities of daily living pain anxiety
発行日	2024-11
出版物タイトル	Global Spine Journal
巻	15巻
号	4号
出版者	SAGE Publications
開始ページ	2286
終了ページ	2299
ISSN	2192-5682
NCID	AA12633225
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39484810
DOI	10.1177/21925682241297948
Web of Science KeyUT	001346141500001
関連URL	isVersionOf https://doi.org/10.1177/21925682241297948

Longitudinal changes and tracking of in-school physical activity in primary school children: four-year longitudinal study

フルテキストURL	fulltext.pdf suppl1.docx suppl2.docx
著者	Sasayama, Kensaku\| Yasunebe, Jin\| Adachi, Minoru\|
キーワード	Physical activity Step counts Moderate-to-vigorous physical activity Youth Recess Physical education Longitudinal study Tracking
発行日	2025-03-18
出版物タイトル	BMC Public Health
巻	25巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	1041
ISSN	1471-2458
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	author
PubMed ID	40102823
DOI	10.1186/s12889-025-22256-8
Web of Science KeyUT	001449530200009
関連URL	isVersionOf https://doi.org/10.1186/s12889-025-22256-8

LeFood-set: Baseline performance of predicting level of leftovers food dataset in a hospital using MT learning

フルテキストURL	fulltext.pdf
著者	Sari, Yuita Arum\| Nakazawa, Atsushi\| Wani, Yudi Arimba\|
発行日	2025-05-19
出版物タイトル	PLoS One
巻	20巻
号	5号
出版者	Public Library of Science
開始ページ	e0320426
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Sari et al.
論文のバージョン	publisher
PubMed ID	40388400
DOI	10.1371/journal.pone.0320426
Web of Science KeyUT	001491376800016
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0320426