検索結果 13368 件
| JaLCDOI | 10.18926/15088 |
|---|---|
| タイトル（別表記） | サーモグラフィーによる体表面温度の測定 |
| フルテキストURL | 067_063_070.pdf |
| 著者 | 保崎 泰弘| 名和 由一郎| 竹内 一昭| 柘野 浩史| 芦田 耕三| 横田 聡| 光延 文裕| 御舩 尚志| 谷崎 勝朗| 越智 浩二| 原田 英雄| 池田 敏| 武田 和久| |
| 抄録 | Body Surface Temperature was observed by thermography. The surface temperature of a healthy person's lower limbs, after being cooled in a water bath, increased in parallel with time. Patients with Diabetes Mellitus had different patterns in the rate of increase of the surface temperature. After cold loading, one patient had a 99% recovery ratio of surface temperature, the same level as healthy volunteers (83%, and 88%), as calculated by a picture processing program with the computerized thermotracer. However, the recovery ratio of other patients was poorer, ranging from 56% to under 6% recovery. This measurement of elevation of body temperature is useful for the estimation of peripheral blood flow in patients with lower limbcirculation failure. |
| キーワード | Thermography (サーモグラフィー) Diabetes Mellitus (糖尿病) Peripheral Circulation (末梢循環) Cold Loading (冷水負荷) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 63 |
| 終了ページ | 70 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307566 |
| JaLCDOI | 10.18926/15087 |
|---|---|
| タイトル（別表記） | 気管支喘息症例に対する鼻腔内ステロイド療法 |
| フルテキストURL | 067_057_062.pdf |
| 著者 | 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 横田 聡| 柘野 浩史| 竹内 一昭| 名和 由一郎| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
| 抄録 | Bronchial asthma is often accompanied with allergic rhinitis or chronic sinusitis. Mucosal abnormalities of sinonasal cavity may influence lower respiratory responses in patients with asthma. We experienced a case of 72-year-old woman with asthma, who had dyspnea on exertion and a large volume of expectoration of more than 100mℓ a day. Furthermore she had nasal symptoms (nasal obstruction and rhinorrea) with prominent post-nasal discharge. Computed tomography (CT) scans of sinonasal cavity revealed marked thickness of nasal mucosa. Although her asthma symptoms such as wheezing and dyspnea improved by administration of bronchodialators, antiallergic agent, and beclomethason di isocyanate (BDI) accompanied with spa therapy after admission, the volume of expectoration revealed no decrease and her peak expiratory flow (PEF) didn't increase. The volume of expectoration and the PEF showed marked improvement after starting of intranasal glucocorticoid therapy. It is suggested from her clinical course that treatment with intranasal glucocorticoids is very important in asthmatic patients with mucosal abnormalities of sinonasal cavity. |
| キーワード | bronchial asthma (気管支喘息) rhinitis (鼻炎) intranasal steroid therapy (鼻腔内吸入ステロイド療法) expectoration (喀痰排出) peak expiratory flow (ピークフロー) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 57 |
| 終了ページ | 62 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307814 |
| JaLCDOI | 10.18926/15056 |
|---|---|
| フルテキストURL | 027_161_172.pdf |
| 著者 | 那須 雅子| |
| 出版物タイトル | 岡山大学大学院社会文化科学研究科紀要 |
| 発行日 | 2009-03-26 |
| 巻 | 27巻 |
| 号 | 1号 |
| 開始ページ | 161 |
| 終了ページ | 172 |
| ISSN | 1881-1671 |
| 言語 | 英語 |
| 著作権者 | 岡山大学大学院社会文化科学研究科 |
| 論文のバージョン | publisher |
| NAID | 120002307908 |
| JaLCDOI | 10.18926/15053 |
|---|---|
| フルテキストURL | 027_103_121.pdf |
| 著者 | ZAW SOE MIN| |
| 出版物タイトル | 岡山大学大学院社会文化科学研究科紀要 |
| 発行日 | 2009-03-26 |
| 巻 | 27巻 |
| 号 | 1号 |
| 開始ページ | 103 |
| 終了ページ | 121 |
| ISSN | 1881-1671 |
| 言語 | 英語 |
| 著作権者 | 岡山大学大学院社会文化科学研究科 |
| 論文のバージョン | publisher |
| NAID | 120002307304 |
| JaLCDOI | 10.18926/fest/15045 |
|---|---|
| フルテキストURL | 014_023_028.pdf |
| 著者 | Chegbeleh Larry Pax| 西垣 誠| Akudago John Apambilla| Alim Md. Abdul| 小松 満| |
| 抄録 | During underground space development, groundwater seepage mostly occurs which may seriously affect the stability of deep excavations as well as retard progress of construction. For smooth progress of work, effective construction and operation of a disposal facility for high level radioactive waste (HLW), it is important to control seepage into excavations by sealing off fractures or fissures and excavation disturbed zones (EDZ) to control groundwater inflow during the construction phase of such a facility. In this study, a series of experiments were conducted on ethanol/bentonite slurries in the laboratory with the aim of determining the effect of a hydrophilic solvent such as ethanol on the hydraulic and injection characteristic of bentonite slurry for the sealing of fissures to control ground water seepage during the construction phase of a repository. Preliminary results revealed ethanol/bentonite slurry as an effective grouting material capable of penetrating micro fractures (100μm or less) and with the permeability of the grouted medium being as low as 10E-7cm/s. The results also show that the effectiveness and efficiency of grouting is dependent on the type of injection and fissure size. Dynamic injection was observed to be efficient as it was able to inject high dense slurry. |
| キーワード | Dynamic injection permeability swelling bentonite clay |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2009-03-16 |
| 巻 | 14巻 |
| 号 | 1号 |
| 開始ページ | 23 |
| 終了ページ | 28 |
| ISSN | 1341-9099 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307422 |
| JaLCDOI | 10.18926/fest/15044 |
|---|---|
| フルテキストURL | 014_017_022.pdf |
| 著者 | Akudago John Apambilla| 西垣 誠| Chegbeleh Larry Pax| 小松 満| Alim Md. Abdul| |
| 抄録 | Soil-groundwater salinity issues have assumed a worldwide dimension. It is believed that when groundwater level is less than 2 m there is the possibility of salinity transfer between the soil and groundwater due to factors such as capillary forces. One-dimensional column tests were conducted in the laboratory to find a suitable capillary cut design. The capillary cut material comprised a 20 cm thick 2–4.7 mm and a combination of 2–4.7 mm and 9.5–19 mm gravel material. In all, four different designs were tested by compacting Oji sand in the various columns. Groundwater level of 0.75 m from the top was maintained while salt solution of 10% concentration was allowed to flow under capillary forces through the columns. The water content in the columns were monitored using frequency domain reflectrometry-vector analyzer (FDR-V) after which soil samples from 10 m interval in each column was taken for electrical conductivity measurements. The results showed that 5 cm thick, 2–4.7 mm gravel sandwiching coarser material (e.g. 5 cm thick 9.5–19 mm or 10 cm thick 9.5–19 mm gravel material) proved to be very useful design to cut capillarity. |
| キーワード | soil-groundwater salinity capillary cut filter media design |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2009-03-16 |
| 巻 | 14巻 |
| 号 | 1号 |
| 開始ページ | 17 |
| 終了ページ | 22 |
| ISSN | 1341-9099 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308001 |
| JaLCDOI | 10.18926/fest/15043 |
|---|---|
| フルテキストURL | 014_013_016.pdf |
| 著者 | Alim Md. Abdul| 西垣 誠| Chegbeleh Larry Pax| Akudago John Apambilla| 小松 満| |
| 抄録 | Soil-water characteristic curve (SWCC) is an important soil function in an unsaturated soil mechanics field for design and analyses of any unsaturated earth structures. Determination of SWCC is not easy and more so time consuming. Generally, ceramic disc with high air-entry value has been used in the pressure plate apparatus for this purpose by many people. Now-a-days membrane filter is being used as a suitable alternative to ceramic disc. However, experience shows, it has disadvantage of breakage after one time use especially with coarse grain soils (sandy soils). In this study, membrane filter with stainless wire mesh was used to solve this problem and the SWWC was compared with the results obtained without wire mesh. Results showed that membrane filter with stainless wire mesh can be used to determine the SWCC for coarse grain soils. |
| キーワード | SWCC Unsaturated sandy soils Membrane filter Stainless wire mesh |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2009-03-16 |
| 巻 | 14巻 |
| 号 | 1号 |
| 開始ページ | 13 |
| 終了ページ | 16 |
| ISSN | 1341-9099 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307956 |
| JaLCDOI | 10.18926/fest/15042 |
|---|---|
| フルテキストURL | 014_001_012.pdf |
| 著者 | 森本 智子| 銭花 知弘| 米谷 祐介| 石川 洋文| |
| 抄録 | The spread of the highly pathogenic avian influenza (H5N1) among domestic poultry and wild birds has caused global concern over the outbreak of an influenza pandemic of H5N1. The "Pandemic Influenza Preparedness Action Plan" determines the strategy against an influenza pandemic in Japan. Simulations were carried out using an individual based model (IBM). The IBM targeted a virtual area with a population of 100,000 using the demographic data of Sapporo-city, Hokkaido. The effectiveness of targeted antiviral prophylaxis (TAP), geographical targeted antiviral prophylaxis (GTAP), school closure, and pre-pandemic vaccination were explored. Moreover, this study focused on infections among children, who have a high attack rate, and analyzed the effectiveness of interventions for school-age targeted antiviral prophylaxis (STAP). Consequently, TAP, which is recommended by the "Pandemic Influenza Preparedness Action Plan", was found to have high effectiveness in the suppression of the outbreak. Moreover, this study showed the importance of intervention among children, such as STAP and school closure, to prevent the spread of H5N1 influenza. |
| キーワード | Influenza Pandemic H5N1 Individual Based Model (IBM) Sapporo |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2009-03-16 |
| 巻 | 14巻 |
| 号 | 1号 |
| 開始ページ | 1 |
| 終了ページ | 11 |
| ISSN | 1341-9099 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307373 |
| JaLCDOI | 10.18926/ESR/15034 |
|---|---|
| タイトル（別表記） | 中国寧夏地域における日照時間から日積算日射量の推定 |
| フルテキストURL | 015_079_086.pdf |
| 著者 | 楊 勤| 塚本 修| |
| 抄録 | For the estimation of daily solar radiation from sunshine duration, observation data of Yinchuan station in Ningxia, China was used. Using a linear relationship between solar radiation and extraterrestrial radiation including relative sunshine duration and daylength, we obtained local coefficients s a =0.18, s b =0.62 from past five years data(1981-1985). Using the same method, coefficients for Guyuan region were confirmed too as a representative of south part of Ningxia province. Applying the local coefficients and calculation formula of solar radiation, we validated daily solar radiation of two years(1986-1987) of Yinchuan station and four years(1991-1994) of Guyuan station. The results showed high correlation coefficients of R2=0.94 in Yinchuan and R2=0.85 in Guyuan. Error analysis was applied using mean bias error(MBE), mean absolute bias error(MABE), root mean square error(RMSE)，mean absolute percentage error(MAPE) on solar radiation of Yinchuan(1973-2006) and Guyuan(1986-2006) stations. Results showed that mean absolute bias error(MABE) was less than 13% and 17% in Yinchuan station and Guyuan station respectively. Then we have applied this method to the estimation of daily solar radiation at ‘Yongning’ station(near Yinchan) with the sunshine duration data at ‘Yongning’. The estimated values were compared with observed daily solar radiation at Yinchuan as past twelve years data(1989-2000). The results showed good linear relationship with high correlation coefficient of R2= 0.88. |
| キーワード | Daily solar radiation Extraterrestrial radiation Relative sunshine duration Local coefficient |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2009-03-31 |
| 巻 | 15巻 |
| 号 | 1号 |
| 開始ページ | 79 |
| 終了ページ | 86 |
| ISSN | 1340-7414 |
| 言語 | 英語 |
| 著作権者 | 岡山大学地球科学研究報告編集委員会 |
| 論文のバージョン | publisher |
| NAID | 120002307142 |
| 著者 | Meltem OKUR DINCSOY| |
|---|---|
| 発行日 | 2009-03-26 |
| 出版物タイトル | 北東アジア経済研究 |
| 巻 | 7巻 |
| 号 | 1号 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/15013 |
| 著者 | 中村 良平| Recky H. E. Sendouw| |
|---|---|
| 発行日 | 2009-03-26 |
| 出版物タイトル | 北東アジア経済研究 |
| 巻 | 7巻 |
| 号 | 1号 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/15012 |
| JaLCDOI | 10.18926/15008 |
|---|---|
| タイトル（別表記） | 中高年発症型喘息患者におけるIgE系アレルギー反応の加令による変化 |
| フルテキストURL | 067_050_056.pdf |
| 著者 | 光延 文裕| 御舩 尚志| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 横田 聡| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
| 抄録 | Age-related changes in IgE-mediated allergic reaction were examined in patients with late onset asthma, whose asthma occured over the age at onset of 40. 1. The number of patients with a high serum IgE level over 3001U/mℓ was larger in those between the ages at onset of 40 and 49 and over age at onset 60 than in those between the ages at onset 50 and 59. 2. A positive RAST score to Hdm and cockroach allergens was more frequently found in patients between 40 and 49 and over age 60 at onset compared to those between 50 and 59 at onset. In contrast, the number of patients with a positive RAST to Candida was larger in those between 50 and 59 at onset than in those of between 40 and 49 and over 60 at onset. 3. Severe asthma was more frequently and slight asthma was less frequently observed in patients between 50 and 59 at onset than in those of the other age at onset groups. These results suggest that IgE-mediated allergic reaction in patients between the ages at onset of 50 and 59 is different from that in those with early onset asthma, and that the reaction in patients between the ages at onset 40 and 49 and over 60 resembles to the reaction in those with early onset asthma. |
| キーワード | IgE RAST 吸入抗原 (inhalant Allergen) 気管支喘息 (Bronchial asthma) 加令 (aging) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 50 |
| 終了ページ | 56 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307989 |
| JaLCDOI | 10.18926/15007 |
|---|---|
| タイトル（別表記） | 温泉療法による気管支喘息患者の心理的障害の改善 |
| フルテキストURL | 067_043_049.pdf |
| 著者 | 横田 聡| 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 竹内 一昭| 名和 由一郎| 谷崎 勝朗| 多田 慎也| 原田 実根| |
| 抄録 | To evaluate improvement of mental disorders by spa therapy for 1-2 months, three kinds of psychological examinations, CMI (Cornel Medical Index), SDS (Selfrating Depression Scale) and CAI (Comprehensive Asthma Inventory) tests, were performed in 37 patients with asthma before and after spa therapy. 1. In CMI test, the scores of physical symptoms, respiratory symptoms, and CIJ symptoms significantly decreased after spa therapy. The score of psychical symptoms tended to decrease after the therapy, however, this was not significant. 2. The mean score of the subjects over 40 points in SDS test significantly decreased from 45.7 points before spa therapy to 37.5 after the therapy. 3. Mental disorders evaluated by various categories in CAI test were significantly improved after spa therapy. The average score in CAI test significantly decreased from 37.1 to 27.8 after the therapy. These results demonstrate that psychological disorders in patients with asthma are improved by spa therapy. |
| キーワード | 気管支喘息 (Bronchial asthma) 温泉療法 (Spa therapy) 心理テスト（CMI, SDS, CAI) (CMI test, SDS test, CAI test) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 43 |
| 終了ページ | 49 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307273 |
| JaLCDOI | 10.18926/15006 |
|---|---|
| タイトル（別表記） | 気管支喘息におけるエゴマ油と白血球のロイコトリエンB4,C4合成 |
| フルテキストURL | 067_035_042.pdf |
| 著者 | 芦田 耕三| 御舩 尚志| 光延 文裕| 保崎 泰弘| 横田 聡| 柘野 浩史| 谷崎 勝朗| 山本 純子| 辻 孝夫| |
| 抄録 | In recent years, it has been noted that there is a close correlation between leukotrienes and late asthmatic reaction (LAR). In this study, effects of dietary supplementation with perilla seed oil rich in alpha-linolenic acid, which is speculated to affect the generation of leukotrienes through metabolism of arachidonic acid (AA), were evaluated in 6 patients with asthma. The symptoms and ventilatory function were improved after 2-week dietary supplementation with perilla seed oil. The generation of LTB4 and LTC4 by peripheral leucocytes stimulated with Ca ionophore A23187 was significantly suppressed by the dietary supplementation (LTB4 and LTC4 ; p<0.05). Regarding the composition of fatty acids in serum phospholipids, the concentrations of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and AA tended to increase after the supplementation, accompanied with an increase in the ratio of EPA to AA. These results suggest that dietary supplementation with perilla seed oil brings beneficial effects in the treatment of asthma. |
| キーワード | n-3系脂肪酸 (n-3 fatty acids) 気管支喘息 (bronchial asthma) アラキドン酸 (arachidonic acid) LTB4 LTC4 |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 35 |
| 終了ページ | 42 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307804 |
| JaLCDOI | 10.18926/15002 |
|---|---|
| タイトル（別表記） | Ia型(単純気管支れん縮型)喘息における気道過敏性について…年齢および気管支肺胞洗浄液中の細胞成分との関連について |
| フルテキストURL | 067_028_034.pdf |
| 著者 | 芦田 耕三| 御舩 尚志| 光延 文裕| 保崎 泰弘| 横田 聡| 柘野 浩史| 竹内 一昭| 名和 由一郎| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
| 抄録 | Bronchial hyperresponsiveness was examined in relation to age, ventilatory function, and the proportion of bronchoalveolar lavage (BAL) cells in 39 patients with type Ia asthma (simple bronchoconstriction) (25 with type Ia-1 and 14 with type Ia-2), classified by clinical symptoms. 1. The proportion of BAL eosinophils was significantly higher in type Ia-2 than that in type Ia-1 asthma patients. 2. Bronchial reactivity to methacholine was not different between type Ia-1 and type Ia-2 asthma patients. 3. Bronchial hyperreactivity tended to decrease as patient age was higher in both types of asthma. Neither ventilatory function (FEV1.0%) nor the proportions of BAL lymphocytes and neutrophils was not correlated with bronchial hyperresponsiveness in both types of asthma. 4. Bronchial reactivity to methacholine more dereased with the increase in the proportion of BAL eosinophils in both type Ia-1 and Ia-2 asthma patients. The results show that bronchial hyperresponsiveness in patients with type Ia asthma is correlated to patients age and the proportion of BAL eosinophils. |
| キーワード | Bronchial hyperresponsiveness Type Ia asthma Patient age BAL eosinophiIs |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 28 |
| 終了ページ | 34 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307134 |
| JaLCDOI | 10.18926/15001 |
|---|---|
| タイトル（別表記） | アトピー型および非アトピー型気管支喘息の発作発症機序の差異について･･･ロイコトリエンC4の役割について |
| フルテキストURL | 067_021_027.pdf |
| 著者 | 芦田 耕三| 御舩 尚志| 光延 文裕| 保崎 泰弘| 横田 聡| 柘野 浩史| 谷崎 勝朗| |
| 抄録 | Concentrations of main bronchoconstricting chemical mediators, histamine and leukotriene C4 (LTC4), were measured in bronchoalveolar lavage (BAL) fluid, and when cells (peripheral leukocytes and BAL cells) were stimulated by Ca ionophore A23187, in 7 atopic and 7 nonatopic asthma patients. 1. The proportion of basophilic cells was significantly larger in atopic than in nonatopic asthma (p<0.05), however no significant difference was present in the other BAL cells between the two asthma types. 2. Concentration of histamine in BAL fluid was significantly higher in atopic than that in nonatopic asthma, however, difference in that of LTC4 was not found between them. 4. The release of LTC 4 from BAL cells was higher in nonatopic than that in atopic asthma, but this was not significant. In contrast, the release of histamine was significantly higher in atopic compared to that in nonatopic asthma (p<0.001) when the cells were stimulated by Ca ionophore A23187. These results suggest that both histamine and LTC4 participate in the onset mechanism of atopic asthma, and only LTC4 in that of nonatopic asthma. |
| キーワード | Histamine LTC4 atopic nonatopic BAL cells |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 21 |
| 終了ページ | 27 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307446 |
| JaLCDOI | 10.18926/15000 |
|---|---|
| タイトル（別表記） | Ⅱ型(細気管支閉塞)喘息と閉塞性細気管支炎における細気管支領域の炎症反応の差 |
| フルテキストURL | 067_014_020.pdf |
| 著者 | 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 横田 聡| 柘野 浩史| 竹内 一昭| 名和 由一郎| 谷崎 勝朗| 多田 慎也| 原田 実根| |
| 抄録 | Ventilatory function and inflammatory cells in airways were compared between patients with type Ⅱ (bronchiolar obstruction) asthma and those with obstructive bronchiolitis. 1. Age and age at onset were higher in patients with type Ⅱ asthma than in those with obstructive bronchiolitis. IgE-mediated allergic reaction was observed in patients with type Ⅱ asthma, but not in those with obstructive bronchiolitis. 2. In ventilatory function tests, all ventilatory parameters examined were lower in patients with type Ⅱ asthma compared to those with obstructive bronchiolitis, and the differences were significant in FEV1.0% (p<0.001), % MMF (p<0.02), and V50 (p<0.01). 3. The proportion of BAL neutrophils was very high in type Ⅱ asthma (55.7%) and obstructive bronchiolitis (74.4%), however, this was not significant. 4. Absolute numbers/BAL fluid of total cells, BAL macrophages and BAL neutrophils were significantly higher in patients with obstructive bronchiolitis than in those with type Ⅱ asthma. 5. The results on absolute number/mℓ of BAL cells demonstrated that number of BAL neutrophils markedly larger in patients with obstructive bronchiolitis compared to those with type Ⅱ asthma. These results show that high proportion of BAL neutrophils was observed in the two respiratory diseases, however, the degree of inflammation in airways was markedly greater in obstructive bronchiolitis. |
| キーワード | Ⅱ型喘息 (Type Ⅱasthma) 閉塞性細気管支炎 (Obstructive bronchiolitis) 換気機能 (Ventilatory function) BAL好中球 (BAL neutrophiIs) IgE系反応 (IgE-mediated allergy) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 14 |
| 終了ページ | 20 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307471 |
| JaLCDOI | 10.18926/14999 |
|---|---|
| タイトル（別表記） | 肺活量(FVC)低値を示す気管支喘息の臨床的特徴 |
| フルテキストURL | 067_008_013.pdf |
| 著者 | 光延 文裕| 御舩 尚志| 保崎 泰弘| 芦田 耕三| 横田 聡| 柘野 浩史| 竹内 一昭| 名和 由一郎| 谷崎 勝朗| 越智 浩二| 原田 英雄| |
| 抄録 | Clinical features of asthma patients with a low % FVC (<75%) were studied in relation to clinical asthma type and disease severity. 1. The value of % FVC was not related to patient age. 2. A significant association between % FVC value and clinical asthma type was found. The value of % FVC was significantly lower in subjects with type Ⅱ asthma (bronchiolar obstruction) than in those with type Ia-1 and type Ia-2 (simple bronchoconstriction) (p<0.001). 3. % FVC value significantly correlated with disease severity. The value in the subjects tended to decrease as their asthma conditions were more severe. 4. The % FVC value in the subjects was improved after treatment (complex spa therapy). These results demonstrate that a significant correlation is present between low % FVC and disease severity in asthma patients with a low % FVC. |
| キーワード | % FVC低値 (Low % FVC) 気管支喘息 (Bronchial asthma) 臨床病型 (Clinical asthma type) 重症度 (asthma severity) 温泉療法 (Spa therapy) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 8 |
| 終了ページ | 13 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308511 |
| JaLCDOI | 10.18926/14998 |
|---|---|
| タイトル（別表記） | BAL液中好中球増加をともなわないⅡ型喘息について |
| フルテキストURL | 067_001_007.pdf |
| 著者 | 谷崎 勝朗| 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 横田 聡| 柘野 浩史| 竹内 一昭| 辻 孝夫| |
| 抄録 | Clinical features of asthma patients with bronchiolar obstruction (type Ⅱ asthma) were studied in relation to the proportion of neutrophils in bronchoalveolar lavage (BAL) fluid. Of 13 subjects studied, 7 were accompanied with BAL neutrophilia (53.5%) (BALn(+)) and 6 were without BAL neutrophilia (3.5%) (BALn(-)). 1. The mean age was higher in BALn(-) (66.0 years) than in BALn(+) patients (55.0 years). 2. Bronchial reactivity to methacholine was slightly higher in BALn(-) patients than in those with BALn(+). 3. The value of FEV1.0% was significantly lower in BALn(+) patints than in those with BALn(-) (p<0.01). 4. The proportion of BAL lymphocytes was signicantly more decreased in BALn(+) patients compared to the proportion in those with BALn(-) (p<0.001). 5. the values of serum IgG, IgA, and IgM were not significantly different between BALn(+) and BALn(-) patients, however, the value of IgG was more decreased in BALn(+) patients than in those with BALn(-). These results suggest that two kinds of type Ⅱ asthma ; one is with BAL neutrophilia related to suppressed immunity, and another is without BAL neutrophilia in part due to aging. |
| キーワード | 気管支喘息 (Bronchial asthma) 細気管支閉塞 (Bronchiolar obstruction) BAL好中球 (BAL neutrophilia) 免疫能低下 (Suppressed immunity) 加齢 (Aging) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1996-11 |
| 巻 | 67巻 |
| 開始ページ | 1 |
| 終了ページ | 7 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308171 |
| JaLCDOI | 10.18926/14991 |
|---|---|
| タイトル（別表記） | 呼吸器疾患のリハビリテーション.気管支喘息の病態的特徴と関連した温泉療法の効果 |
| フルテキストURL | 068_080_093.pdf |
| 著者 | 谷崎 勝朗| 御舩 尚志| 光延 文裕| 保崎 泰弘| 芦田 耕三| 柘野 浩史| 岡本 誠| 岩垣 尚志| 山本 和彦| |
| 抄録 | The number of patients with respiratory disease in the elderly has been increasing in recent years. Pathophysiological characteristic of respiratory diseases in older patients is clearly different from that in younger patients. In this study, rehabilitation for patients with respiratory disease, particularly bronchial asthma, in the elderly was discussed in relation to pathophysiology of asthma. Complex spa therapy has two kinds of actions, direct and indirect actions. Subjective and objective symptoms of patients with asthma are improved by spa therapy for 1-2 months, accompanied with improvement of ventilatory function, and decrease in bronchial hyperresponsiveness and respiratory resistance. In addition to these direct action of spa therapy, increase in strength of respiratory muscle, stability of autonomic nerve syetem, psychical relaxation, and inprovement of suppressed function of adrenocortical glands are observed as indirect action of spa therapy. Regarding clinical asthma type classified by pathophysiological changes of the airways, spa therapy was more effective in patients with hypersecretion and bronchiolar obstruction. These results suggest that complex spa therapy is available as rehabilitation and/or treatment for patients with respiratory disease. |
| キーワード | 気管支喘息 (Bronchial asthma) リハビリテーション (rehabilitation) 複合温泉療法 (complex spa therapy) 換気機能 (ventilatory function) 副腎皮質 (adrenocortical glands) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1997-12 |
| 巻 | 68巻 |
| 開始ページ | 80 |
| 終了ページ | 93 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308151 |