検索結果 13368 件
| JaLCDOI | 10.18926/15306 |
|---|---|
| タイトル（別表記） | 気管支喘息における気道内への好中球の出現とその意義 換気機能と関連して |
| フルテキストURL | 063_025_029.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 谷水 将邦| 本家 尚子| 草浦 康浩| 木村 郁郎| |
| 抄録 | Ventilatory function was compared between two age-matched asthma groups : group A (study group) consists of 8 patients with bronchial asthma with marked neutrophilia (20% or more) in the BAL fluid and group B (control group) of 8 patients with neutrophils (less than 5% of total BAL cells). The values of six ventilatory parameters were lower in group A than in group B, and a significant difference was found in FEV(1.0%), % MMF, % V(50) and % V(25) between groups A and B. Of these parameters, the value of % V(25) was markedly decreased in group A compared with group B. The results show that ventilatory dysfunction in airways, especially in small airways, is closely correlated to increased number of neutrophils in BAL fluid. |
| キーワード | ventilatory function (換気機能) neutrophils in BAL fluid (好中球, BAL) small airways (細気管支) bronchial asthma (気管支喘息) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1992-06 |
| 巻 | 63巻 |
| 開始ページ | 25 |
| 終了ページ | 29 |
| ISSN | 0913-3771 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307993 |
| JaLCDOI | 10.18926/15305 |
|---|---|
| タイトル（別表記） | 気管支喘息における気道炎症反応の臨床的意義｡慢性閉塞性細気管支炎との比較検討 |
| フルテキストURL | 064_024_030.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 御船 尚志| 光延 文裕| 梶本 和宏| 杉本 啓介| 横田 聡| 平松 順一| 瓦屋 正志| 越智 浩二| 原田 英雄| 多田 慎也| 木村 郁郎| |
| 抄録 | Clinical significanoce of airway inflammation was assessed in 28 patients with bronchial asthma, and the results were compared with those in 9 patients with chronic obstructive bronchiolitis (COB). 1. Total cell number in bronchoalveolar lavage(BAL) fluid was markedly increased in patients with COB (51.0×10(6)), which was significantly greater than that in those with bronchial asthma (9.6×10(6) ). 2. The proportion of BAL macrophages was significantly higher in patients with bronchial asthma than in those with COB. However, the, absolute number of BAL macrophages was not significantly different between them. 3. The proportion of BAL lymphocytes was higher in patients with bronchial asthma than in those with COB, but this difference was not signifcant. In contrast, the absolute number of BAL lymphocytes was significantly greater in patients with COB than in those with bronchial asthma. 4. The proportion and the number of BAL neutrophils were markedly increased in patients with COB compared to those with bronchial asthma. 5. The proportion and the number of BAL eosinophils were higher in patients with bronchial asthma than in those with COB, although these defferences were not significant. The results suggest that airway inflammation in bronchial asthma is not so intensive as that in COB. |
| キーワード | airway inflammation (気道炎症反応) bronchial asthma (気管支喘息) chronic obstructive bronchiolitis (慢性閉塞性細気管支炎) lymphocytes (リンパ球) neutrophils (好中球) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1993-06 |
| 巻 | 64巻 |
| 開始ページ | 24 |
| 終了ページ | 30 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307730 |
| JaLCDOI | 10.18926/15304 |
|---|---|
| タイトル（別表記） | 気管支喘息における気道内への好酸球の出現とその意義. 過分泌と関連して. |
| フルテキストURL | 063_014_018.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 木村 郁郎| |
| 抄録 | A correlation between the proportion of eosinophils in bronochoalveolar lavage (BAL) fluid and amount of expectoration was examined in patients with atopic asthma. The subjects were divided into two groups : cases with high proportion (20% of more) (group A) and low proportion (less than 5%) (group B) of eosinophils in the BAL fluid. Any significant difference was not paesent in the value of each ventilatory parameter between the two groups. The amount of expectoration/day was significantly higher in group A compared with group B (p<0.001). These results suggest that eosinophilia in BAL fluid correlates to mucus hypersecretion in the airways of patients with atopic asthma. |
| キーワード | Eosinophilia (好酸球) Hypersecretion (過分泌) BAL fluid (BAL) bronchial asthma (気管支喘息) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1992-06 |
| 巻 | 63巻 |
| 開始ページ | 14 |
| 終了ページ | 18 |
| ISSN | 0913-3771 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307156 |
| JaLCDOI | 10.18926/15303 |
|---|---|
| タイトル（別表記） | 気管支喘息におけるActivated Tリンパ球について,喘息発作との関連 |
| フルテキストURL | 064_011_016.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 御船 尚志| 光延 文裕| 梶本 和宏| 杉本 啓介| 横田 聡| 平松 順一| 瓦屋 正志| 原田 英雄| 多田 慎也| 木村 郁郎| |
| 抄録 | The number of CD4(+) T-Iymphocytes, CD4/CD8 ratio, and the number of IL2R(+) T-Iymphocytes (CD25) were examined in 14 patients with bronchial asthma, and the results were compared in three different asthma stages : symptom-free stage, wheeze stage, and attack stage. 1. The proportion of blood CD4(+) T-lymphocytes was more decreased in patients with asthma attacks than in those without symptoms. The CD4/CD8 ratio was also more decreased in patients with attacks than in those without symptoms. However, these differences were not significant. 2. The proportion of blood activated T cells (IL2R(+) cells, CD25) was significantly increased in patients with attacks than in those without symptoms. The proportion of activated T cells in 5 asthma patients was 2.9±0.8% in symptom-free stage and 6.6±1.1% in attack stage(p<0.001). These findings show that numbers of activated T-lymphocytes in peripheral blood were increased during asthma attacks, and this increase suggests the participation of activated T cells in the pathogenesis of asthma. |
| キーワード | CD4(+) T cells (CD4(+)リンパ球) CD4／CD8 ratio (CD4／CD8比) IL2R(+) T cells (IL2R(+)Tリンパ球) bronchial asthma (気管支喘息) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1993-06 |
| 巻 | 64巻 |
| 開始ページ | 11 |
| 終了ページ | 16 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307394 |
| JaLCDOI | 10.18926/15302 |
|---|---|
| タイトル（別表記） | 気管支喘息における気道内リンパ球の出現とその意義.IgE系反応との関連について. |
| フルテキストURL | 063_019_024.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 谷水 将邦| 本家 尚子| 草浦 康浩| 木村 郁郎| |
| 抄録 | Relationship of the proportion of lymphocytes in bronchoalveolar lavage (BAL) fiutd to IgE-mediated reactions and to ventilatory function was studied in two age-matched asthma groups : group A of 11 subjects with BAL lymphocytes over 30% and group B of 11 subjects with BAL leyphocytes less than 10%. Of the eleven subjects in group A, 3 (27.3%) were atopic and 4 (36.4%) were non-atopic. The proportion of BAL lymphocytes in subjects with serum IgE level more than 300 IU/ml, who were all older than 50 years, was significantly higher than that in subjects with serum IgE less than 100 IU/ml in group A (p<0.05). While of the eleven subjects of group B, 5 (45.5%) were atopic and 4 (36.4%) were non-atopic. The value of % V(25) was significantly higher in the atopics compared with the non-atopics in group A (p<0.05), although no significant difference was found in the value of % V(25) between the two asthma types in group B. The results show that an increased number of lymphocytes in BAL fluid may be enhanced by IgE-mediated allergic reactions in the elderly, and that the decreased value of % V(25) may be associated withan increased number of lymphocytes in BAL fluid in non-atopics. |
| キーワード | Lymphocytes (リンパ球) BAL fluid (BAL液) IgE antibody (IgE抗体) bronchial asthma (気管支喘息) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1992-06 |
| 巻 | 63巻 |
| 開始ページ | 19 |
| 終了ページ | 24 |
| ISSN | 0913-3771 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307202 |
| JaLCDOI | 10.18926/15301 |
|---|---|
| タイトル（別表記） | 気管支喘息における副腎皮質ホルモン長期投与による免疫抑制と気管支肺胞洗浄液中好中球増多との関連 |
| フルテキストURL | 064_017_023.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 御船 尚志| 光延 文裕| 梶本 和宏| 杉本 啓介| 横田 聡| 平松 順一| 瓦屋 正志| 原田 英雄| 木村 郁郎| |
| 抄録 | Cellular composition of bronchoalveolar lavage (BAL) fluid was compared between two age-matched steroid-dependent intractable asthma (SDIA) groups : 17 group A patients (serum IgG level < 1000mg/dℓ) whose immunity was regarded as being suppressed by long-term glucocorticoid therapy and 17 group B patients (serum IgG level > 1200mg/dℓ). 1. The levels of serum IgA and IgM were significantly decreased in group A compared to the levels in group B patients. 2. The number of blood lymphocytes was also significantly lower in group A than in group B patients. However, the number of blood neutrophils was not different between the two asthma groups. 3.The number of BAL lymphocytes was significantly lower in group A than in group B patients. 4. BAL neutrophilia (more than 1.5×10 (4)/mℓ) was observed in 6 of the 17(35.3%) patients in group A, but not observed in any patients in group B. The number of BAL neutrophils was significantly greater in group A than in group B patients. These results suggest that there is a correlation between immunosuppression by glucocorticoids and BAL neutrophilia in patients with bronchial asthma. |
| キーワード | immunosuppression (免疫抑制) BAL neutrophilia (BAL好中球増多) glucocorticoids (副腎皮質ホルモン) bronchial asthma (気管支喘息) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1993-06 |
| 巻 | 64巻 |
| 開始ページ | 17 |
| 終了ページ | 23 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307882 |
| JaLCDOI | 10.18926/15299 |
|---|---|
| タイトル（別表記） | ステロイド依存性重症難治性喘息に対する温泉療法の重要性｡過去10年間の181例を対象に。 |
| フルテキストURL | 064_001_010.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 御船 尚志| 光延 文裕| 梶本 和宏| 杉本 啓介| 横田 聡| 平松 順一| 瓦屋 正志| 越智 浩二| 原田 英雄| 多田 慎也| 木村 郁郎| |
| 抄録 | Characteristics of 181 patients with steroid-dependent intractable asthma (SDIA) who were admitted to our hospital and had spa therapy for last 10 years were examined in relation to the methods of spa therapy. For last 10 years, three kinds ofspa therapies were administered: spa therapy A (swimming training in a hot spring pool) in the first atage (1982-1985), spa therapy B (swimming training + inhalation of iodine salt solution) in the middle stage (1986 -1989), and spa therapy C (swimming training + inhalation of iodine salt solution + fango therapy) in the last stage (1990-1991) of this study. 1. The number of patients with SDIA who were admitted to our hospital and had spa therapy tended to increase from 2 in 1986 to 35 in 1991. 2. The number of SDIA patients over the age of 60 or over the age at onset of 40 tended to increase from the first stage to the last stage. 3. The proportion of patients from distant areas (prefectures other than Tottori) was decreasing for the last stage, although the number of these patients was increasing in recent years. 4. The proportions of patients divided by serum IgE levels and by clinical asthma types did not change for last 10 years. 5. The proportion of type Ib and type II asthma was considerably high in patients with SDIA for last 10 years. 6. Clinical effects of spa therapy were observed in 21 of the 30 (70.0%)patients with SDIA in the first stage (1982-1985) with spa therapy A, 68 of the 83 (74.7%) patients with SDIA in the middle stage (1986-1989) with spa therapy B, and 61 of the 68 (89.7%) patients with SDIA in the last stage (1990-1991) with spa therapy C. |
| キーワード | swimming training in a hot spring pool (温泉プール水泳訓練) inhalation of iodine salt solution (ヨードゾル吸入) fango therapy (鉱泥湿布療法) SDIA |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1993-06 |
| 巻 | 64巻 |
| 開始ページ | 1 |
| 終了ページ | 10 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307391 |
| JaLCDOI | 10.18926/15298 |
|---|---|
| タイトル（別表記） | ステロイド依存性重症難治性喘息に対する複合温泉療法の作用機序 |
| フルテキストURL | 063_001_006.pdf |
| 著者 | 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御船 尚志| 光延 文裕| 高取 明正| 奥田 博之| 越智 浩二| 原田 英雄| 木村 郁郎| |
| 抄録 | Effects of complex spa therapy, which comprises swimming training in a hot spring pool, inhalation of iodine salt solution and fango therapy, were analyzed in patients with steroid-dependent intractable asthma (SDIA) by comparison between the subjects with and without efficacy of the therapy. 1. The complex spa therapy was effective in the patients with lower levels of FEV(1.0%) and % PEFR. 2. The complex spa therapy was not always effective in the patients with a low value of % V(25), which represents depressed airflow in the small airways. 3. The efficacy of the complex spa therapy was found in the patients showing a low value of % V(25) accompanied by BAL neutrophilia, but not found in those without increased proportion (more than 10% ) of neutrophils in BAL fluid. The results reveal that the complex spa therapy is effective in patients with SDIA showing low values of FEV(1.0%) and % PEFR, and in those with a low value of % V(25) and BAL neutrophilia. |
| キーワード | complex spa therapy (複合温泉療法) ventilatory function (換気機能) BAL neutrophilia (BAL好中球増多) bronchial asthma (気管支喘息) |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 1992-06 |
| 巻 | 63巻 |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 0913-3771 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307537 |
| JaLCDOI | 10.18926/15297 |
|---|---|
| フルテキストURL | Mem_Fac_Eng_OU_33_2_97.pdf |
| 著者 | 神代 充| 大崎 紘一| 梶原 康博| 宗澤 良臣| Tano Masakazu| Okamoto Katsuyuki| Nishino Akira| Okamoto Asao| Nishimori Naoki| |
| 抄録 | We propose the recognition method of bridge soldering base metal on the circuits by comparing CAD figure and input image of image processing to locate the soldering iron tip accurately to secure the high quality Firstly, three dimensional CAD assembly drawing of circuits which are assembled perpendicularly in each other is projected on an imaginary two dimensional screen which is vertical to the optical axis of the camera The projected image is used as the standard CAD figure to inspect the location of the bridge soldering base metal. The positions among the bridge soldering base metals show the line state. So this line (connecting line) is used as the reference line to inspect the location of the bridge soldering base metal. The characteristics of the standard figure are represented by the connecting line, edge line and center points of base metal. Secondly, the position and gradient of connecting line among bridge soldering base metals in the input image is estimated. And the position of base metal and assembly accuracy of circuit units are calculated by comparing the shape and position of each base metal with its standard figure based on the connecting line Furthermore, the length between the opposite edges of the base metals are calculated to inspect the positions and the assemble accuracy of circuit units. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 1999-04-27 |
| 巻 | 33巻 |
| 号 | 2号 |
| 開始ページ | 97 |
| 終了ページ | 103 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307283 |
| JaLCDOI | 10.18926/15289 |
|---|---|
| タイトル（別表記） | 変形性膝関節炎患者膝関節液中の細胞外マトリックス成分と可溶性VCAM-1 |
| フルテキストURL | 007_2_099_103.pdf |
| 著者 | 唐下 博子| 一村 光子| 崎山 順子| 岡本 基| 中田 安成| 遠藤 浩| |
| 抄録 | It is generally accepted that the number of patients with osteoarthritis (OA) of the knee must increase in the future because of the increase of the aged. The pathogenic mechanisms of OA haven't been elucidated yet, but it is supposed that mediate pannus may cause the factors for irreversible cartilage damage in the inflammatory process. Therefore it is very important to find and predict OA at the early stage. Now there were many indices to determine joint damage with OA, for example, cytokines including IL, TNF, TGF, matrix metalloproteinase (MMPs), tissue inhibitor of metalloproteinase (TIMPs), proteoglycan (PG), hyaluronate (HA), super oxide, adhesion molecules including, ICAM-1, VCAM-1 and PECAM. In this study, we measured that the soluble VCAM-1 (sVCAM-1), soluble collagen (sCOLL), heparansulfate proteoglycan (HSPG), uronic acis and CRP in synovial fluids (SF) with OA. A positive correlation between the level of sVCAM-1 and sCOLL (ρ = 0.652) was noted. However there was no factor showing a correlation with CRP. It was suggested that the levels of sVCAM-1 and sCOLL in the synovia fluid were active inflammation indices of knee damage, as the different aspects from CRP. The level of HSPG also showed a unique trend because HSPG on the cell surface was quickly digested endocytosis, so that it was not suitable for the inflammatory index in synovial fluid with OA. |
| キーワード | 変形性膝関節炎 (Osteoarthritis) 細胞外マトリックス (Extracellular matrix) 可溶性VCAM-1 (Soluble VCAM-1) 可溶性コラーゲン (Soluble Collagen) 可溶性ヘパラン硫酸プロテオグリカン (Soluble HSPG) |
| 出版物タイトル | 岡山大学医療技術短期大学部紀要 |
| 発行日 | 1997-01-31 |
| 巻 | 7巻 |
| 号 | 2号 |
| 開始ページ | 99 |
| 終了ページ | 103 |
| ISSN | 0917-4494 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307341 |
| JaLCDOI | 10.18926/15269 |
|---|---|
| フルテキストURL | Mem_Fac_Eng_OU_35_47.pdf |
| 著者 | 堂前 行宏| 小西 正躬| 今井 純| Asada, Hideki| Kitamura, Akira| |
| 抄録 | In this paper, an identification method of motor parameters for the diagnosis of rotor bar defects in the squirrel cage induction motor is proposed. It is difficult to distinguish the degree of deterioration by a conventional diagnostic method such as Fourier analysis. To overcome the difficulty, a motor simulator is used to identify the degree of deterioration of rotors in the squirrel cage induction motor. Using this method, the deterioration of rotor bars in the motor can be estimated quantitatively. |
| 出版物タイトル | Memoirs of the Faculty of Engineering, Okayama University |
| 発行日 | 2001-03-27 |
| 巻 | 35巻 |
| 号 | 1-2号 |
| 開始ページ | 47 |
| 終了ページ | 51 |
| ISSN | 0475-0071 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307181 |
| JaLCDOI | 10.18926/15268 |
|---|---|
| タイトル（別表記） | ヒト血清リポタンパク質とシクロデキストリンのアガロースゲル内における相互作用 |
| フルテキストURL | 007_2_093_097.pdf |
| 著者 | 一村 光子| 唐下 博子| 崎山 順子| 森 秀治| 伊藤 昔子| 中田 安成| 遠藤 浩| |
| 抄録 | Cyclodextrins (CDs) are cyclic oligosaccharides with low molecular weight. They have been known to bind to some serum lipoproteins and to form complexes. To elucidate whether each serum lipoprotein subclass could be separated by electrophoresis using CDs, we performed preliminary experiment, in which lipoprotein-CDs interaction was examined on electrophoresis with agarose gel. When the supporting agarose gel containing both α-CD and β-CD was prepared and was applied to isoelectric focusing for fractionating serum lipoproteins, apoB lipoproteins were found to be clearly separated into several fractions on this electrophoresis. This finding suggested that apoB lipoprotein may be detected as isolated form by arranging amounts of added CDs. |
| キーワード | 血清apoB含有リポタンパク質 (serum apoB lipoprotein) シクロデキストリン (cyclodextrin) 等電点電気泳動 (isoelectric focusing (IEF)) agarose gel |
| 出版物タイトル | 岡山大学医療技術短期大学部紀要 |
| 発行日 | 1997-01-31 |
| 巻 | 7巻 |
| 号 | 2号 |
| 開始ページ | 93 |
| 終了ページ | 97 |
| ISSN | 0917-4494 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307426 |
| JaLCDOI | 10.18926/15261 |
|---|---|
| タイトル（別表記） | 現像温度および時間のマンモフイルム特性に与える影響 |
| フルテキストURL | 008_2_121_129.pdf |
| 著者 | 丸山 敏則| 後藤 佐知子| 東 義晴| 中桐 義忠| 渋谷 光一| 杉田 勝彦| 竹内 知行| 本田 貢| 吉田 彰| |
| 抄録 | The influence for developing temperature and processing time within film processing conditions was investigated using four mammographic films, Konica New CM, Fuji UM-MA HC, Kodak Min-R M and Kodak EB/RA (for rapid system). And Fuji UR-2, a double-emulsion film, was used as a control. Those sensitometric strips exposed by a sensitometer were processed in the different combinations of developing temperatures ranging from 28 to 36℃, processing times from 45 to 210 sec. Average gradient, relative speed and base plus fog obtained from the measured film characteristic curves were evaluated for the different developing temperatures and times. Fuji UR-2 was scarcely affected and mammographic films were greatly affected in the different combinations without an increase in base plus fog except EB/RA. In New CM, UM-MA HC and Min-R M, the average gradients and the relative speeds increased as the developing temperature was higher and the developing time was longer, but the increases were limit on the combination of 36℃ and 210 sec in New CM and UM-MA HC. In EB/RA, the average gradients were almost constant and the relative speeds increased slightly like the double-emulsion film. These results suggested that it would be possible to contribute to dose reduction and advancement of contrast in New CM, UM-MA HC and Min-R M by changing these processing parameters. |
| キーワード | マンモグラフィ (Mammography) 現像処理パラメータ (Processing Parameter) 特性曲線 (Characteristic Curve) 平均階調度 (Average Gradient) 相対感度 (Relative Speed) |
| 出版物タイトル | 岡山大学医療技術短期大学部紀要 |
| 発行日 | 1998-01-31 |
| 巻 | 8巻 |
| 号 | 2号 |
| 開始ページ | 121 |
| 終了ページ | 129 |
| ISSN | 0917-4494 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307943 |
| JaLCDOI | 10.18926/15257 |
|---|---|
| タイトル（別表記） | 1997年岡山県下に発生した集団食中毒患者から分離された腸管出血性大腸菌EHEC O157 : H7のパルスフィールドゲル電気泳動法による遺伝子解析 |
| フルテキストURL | 008_2_091_095.pdf |
| 著者 | 宮本 寛治| 坂本 一成| 新谷 勝美| 陳 静| 阿部 絵理子| 岡崎 愉加| 白井 喜代子| 合田 典子| |
| 抄録 | Thirteen enterohemorrhagic Escherichia coli O157 : H7 (EHEC) isolates derived from the patients of an outbreak in the R-hospital in Okayama Japan and one isolated from the ingredients of Japanese noodles in June 1997 were analyzed by molecular typing using pulsed-field gel electrophoresis (PFGE). The PFGE patterns of the patients were almost the same as the patterns of the Japanese noodle ingredients. Therefore, the EHEC O157 : H7 derived from the food was considered to have caused the outbreak in the R-hospital. The molecular typing of isolates from the patients and the Japanese noodle ingredients was almost the same as that of isolates from outbreaks in Hiroshima and Fukuoka prefectures classified as type Ia in 1996 by PFGE analysis. These results indicate that EHEC O157 : H7 strains with a similar PFGE type Ia pattern have already spread throughout western Japan since last year. |
| キーワード | EHEC O157: H7 (腸管出血性大腸菌EHEC O157 : H7) PFGE (パルスフィールドゲル電気泳動法) outbreak (集団感染) molecular typing (遺伝子解析) |
| 出版物タイトル | 岡山大学医療技術短期大学部紀要 |
| 発行日 | 1998-01-31 |
| 巻 | 8巻 |
| 号 | 2号 |
| 開始ページ | 91 |
| 終了ページ | 95 |
| ISSN | 0917-4494 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307383 |
| JaLCDOI | 10.18926/15254 |
|---|---|
| タイトル（別表記） | ヒスチジンタグを持つホスファカンコア蛋白の大腸菌での発現と精製 |
| フルテキストURL | 009_2_105_111.pdf |
| 著者 | 伊藤 昔子| 岡本 基| 森 秀治| |
| 抄録 | Specific regions of core protein of phosphacan, one of the chondroitin sulfate proteoglycans, were expressed as fusion proteins with histidine-tag (His-tag) in Escherichia coli (E.coli) and were affinity purified using nickel-nitrilotriacetic acid (Ni-NTA) matrix. cDNA fragments encoding amino acid residues 343-446 (P3) and 1-340 (P4) of phosphacan core protein were amplified by polymerase chain reaction from E18 rat brain mRNA as template. The amplified products were subcloned into pQE30 vector and were introduced into E.coli strain M15 [pREP4] for the expression. The His-tagged fusion proteins were expressed by cultivating the transformants at 37℃ for 5h in the presence of 1mM IPTG. His-tagged P3 fusion protein (His-P3) was expressed as soluble form, and was purified using Ni-NTA matrix. His-tagged P4 fusion protein (His-P4) which was sequestered into insoluble inclusion bodies was treated with 8.0M urea to solubilize, and then was purified under denaturing conditions. |
| キーワード | phosphacan (ホスファカン) core protein (コア蛋白) His-tagged proteins recombinant protein (融合蛋白) |
| 出版物タイトル | 岡山大学医療技術短期大学部紀要 |
| 発行日 | 1999-02-26 |
| 巻 | 9巻 |
| 号 | 2号 |
| 開始ページ | 105 |
| 終了ページ | 111 |
| ISSN | 0917-4494 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307302 |
| JaLCDOI | 10.18926/15252 |
|---|---|
| タイトル（別表記） | Extended-cycle processによる乳房撮影用増感紙／フィルムシステムの画質改善 |
| フルテキストURL | 009_2_083_090.pdf |
| 著者 | 後藤 佐知子| 丸山 敏則| 東 義晴| 中桐 義忠| 竹田 芳弘| 杉田 勝彦| 木村 文江| 門久 繁文| |
| 抄録 | Extended-cycle process is the term used for a processor in which the processing time has been prolonged usually to approximate 210 seconds. It has been known that the extended-cycle process of some single-emulsion films as used for mammography may enhance film contrast and increase film speed. So the speed was increased in lower speed and higher resolution system than conventional systems by means of using the extended-cycle process in this paper. We investigated how much the resolution of the system was kept. A single screen-single emulsion combination, Konica M-100/CM-H was employed as a low speed and high resolution system. This film after exposure was processed in the different combinations of developing temperatures, 30, 32 and 34℃, and processing time of 210 seconds. On the other hand, Konica M-200/CM-H was employed as a high speed system. This film was processed in the standard-cycle processing (34℃, 90 seconds). Those systems were compared on contrast, speed, screen-film blur and noise by a characteristic curve, MTF (modulation transfer function) and WS (wiener spectrum). Furthermore, the RMI 165 phantom was used to evaluate visibility of mammographic details of these systems. As a result, in the extended-cycle process at the developing temperatures of 32 or 34°C and processing time of 210 seconds for M-100/CM-H, it was possible to increase the speed as much as the higher speed system, M-200/CM-H. Then the contrast, the MTF and the visibility were also improved as compared to the higher speed system. Furthermore patient dose could be reduced at the developing temperature of 34℃ and processing time of 210 seconds in M-100/CM-H. |
| キーワード | image quality mammography single screen-single emulsion film system high-resolution screen extended-cycle process |
| 出版物タイトル | 岡山大学医療技術短期大学部紀要 |
| 発行日 | 1999-02-26 |
| 巻 | 9巻 |
| 号 | 2号 |
| 開始ページ | 83 |
| 終了ページ | 90 |
| ISSN | 0917-4494 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307881 |
| JaLCDOI | 10.18926/15236 |
|---|---|
| タイトル（別表記） | ラテンアメリカにおける肺吸虫の種類 |
| フルテキストURL | 012_1_001_005.pdf |
| 著者 | 頓宮 廉正| |
| 抄録 | Six species of Paragonimus are presently known in Latin America. They include the following : P. mexicanus, P. peruvianus, P. amazonicus, P. inca, P. ecuadoriensis, and P. caliensis. Among them, P. peruvianus has been recognized as a synonym of P. mexicanus by Miyazaki himself, the discoverer of P. peruvianus. Furthermore, P. ecuadoriensis is suggestive of a synonym of P. mexicanus by Miyazaki. I also regard P. amazonicus, P. inca and P. caliensis as dependent species. I entertain a strong suspicion that these are synonymous with P. mexicanus. Therefore, P. mexicanus is the only species that distinctly inhabits Latin America. In the classification, in particular Paragonimus, we have to recognize the variations in the same species. |
| キーワード | Paragonimus (肺吸虫) taxonomy (分類） Latin America (ラテンアメリカ) |
| 出版物タイトル | 岡山大学医学部保健学科紀要 |
| 発行日 | 2001-12-25 |
| 巻 | 12巻 |
| 号 | 1号 |
| 開始ページ | 1 |
| 終了ページ | 5 |
| ISSN | 1345-0948 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308011 |
| JaLCDOI | 10.18926/15230 |
|---|---|
| タイトル（別表記） | マイクロコントローラを組み込んだ歯科インプラント動揺測定装置の開発 |
| フルテキストURL | 012_2_107_117.pdf |
| 著者 | クスマ ウイジャヤ サストラ| 岡 久雄| 更谷 啓治| 松谷 善雄| 龍田 光弘| 川添 堯彬| 小嶋 英幹| |
| 抄録 | The aim of this study was to develop a portable device (IM checker) for measuring dental implant mobility using a microcontroller. A constant amplitude and frequency vibration was applied to a dental implant model and the acceleration signal was detected using measuring probe. Then the IM score was obtained using the criteria developed in this study. We made several implant models of different implant lengths, diameters and material of Rigolac® or Molteno®. There was a linear relationship between mechanical mobility at 400 Hz of the models and the IM scores (R(2) = 0.92). The IM checker could discriminate the mobility of dental implant models in twelve measurements with P < 0.01. There was no significant difference in the means of the IM score measured by four operators with P < 0.01. The results indicated that the IM checker had sufficient reliability and could be available in dental clinics. |
| キーワード | Tooth mobility (歯の動揺) mechanical mobility (機械モビリティ) dental implant (インプラント) manual examination (触診) |
| 出版物タイトル | 岡山大学医学部保健学科紀要 |
| 発行日 | 2002-03-20 |
| 巻 | 12巻 |
| 号 | 2号 |
| 開始ページ | 107 |
| 終了ページ | 117 |
| ISSN | 1345-0948 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307430 |
| JaLCDOI | 10.18926/15229 |
|---|---|
| タイトル（別表記） | 加温後のtsAF8細胞の細胞周期 |
| フルテキストURL | 012_2_101_106.pdf |
| 著者 | 澁谷 光一| 川崎 祥二| 黒田 昌宏| 浅海 淳一| 加藤 博和| 平木 祥夫| |
| 抄録 | Thermotolerance in tsAF8 cells develops during incubation at 34℃ after heating at 45℃, while it is suppressed by the following incubation at a non-permissive temperature of 39.7℃ after the same heating. The incubation temperature after heating may affect the cell cycle and consequently thermotolerance. In the present study, a relationship between the thermotolerance and the cell cycle of tsAF8 was investigated. The cell cycle fractions and DNA synthesis were measured by flow cytometry using double staining with propidium iodide and bromodeoxyuridine. When the tsAF8 cells were heated at 45℃ for 20 min, and thereafter incubated at 34℃, bromodeoxyuridine uptake in the S phase cells (DNA synthesis) was recovered to 65.1% 6 h after the heating, and the cells showed gradual accumulation in the G(2)/M phase. When the cells were incubated at 39.7℃ after heating at 45℃ for 20 min, then showed inhibition of thermotolerance development, the DNA synthesis was recovered to 15.1% temporarily 6 h after the heating, but it became 0% after 12 h, and the cells did not remarkably accumulate in any phases of the cell cycle. This inhibition of DNA synthesis at 39.7℃ was considered to be the result of cell survival decreasing by a step-down heating. However, the relationship between the thermotolerance and the cell cycle was not found out in tsAF8 cells, because the cells did not accumulate in any phases of the cell cycle under the inhibitory condition of thermotolerance. |
| キーワード | thermotolerance (温熱耐性) hyperthermia (ハイパーサーミア) tsAF8 cell cycle (細胞周期) |
| 出版物タイトル | 岡山大学医学部保健学科紀要 |
| 発行日 | 2002-03-20 |
| 巻 | 12巻 |
| 号 | 2号 |
| 開始ページ | 101 |
| 終了ページ | 106 |
| ISSN | 1345-0948 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307264 |
| JaLCDOI | 10.18926/15228 |
|---|---|
| タイトル（別表記） | 放射線エネルギーの違いによる喉頭癌における吸収線量の影響 |
| フルテキストURL | 012_2_091_099.pdf |
| 著者 | 青山 英樹| 中桐 義忠| 井上 光広| 稲村 圭司| 田原 誠司| 宇野 弘文| 森岡 泰樹| 平木 祥夫| |
| 抄録 | We investigated the usefulness of Gafchromic MD-55 film (Nuclear Associates, Inc.) for measuring the radiation doses on the radiotherapy of laryngeal cancers. Since larynx has thin wedge-shaped structure in anterior neck adjacent to airway, the radiation doses to the lesion may be diminished because of build-up and build-down. So, the dose has been measured with conventional measuring systems such as thermoluminescent dosimetry (TLD). However, it was not possible to evaluate the dose distribution correctly using TLD, because it is impossible to float a TLD chip in an air cavity. In this study, we employed Gafchromic MD-55 film as a dosimeter, for it can be set on the area of interest and with a measurability of dose range of 3 to 100 Gy, though it has no energy dependency. And this radiometer is composition near the soft tissue of the human body. The dose distributions to larynx were investigated with this film using neck phantom under each radiation beam energy of 4, 6 and 10 MV x-rays. Our neck phantom is made from acrylic resin and simulates a normal larynx on the basis of image information of computed tomography (CT). Moreover we observed secondary build-up and build-down curves in tissue in the vicinity of air cavities, especially at 10 MV x-rays. These findings suggest that patients with TI-T2 glottic cancers with anterior commissure invasion may receive more effective treatment with 4 MV x-rays rather than with 6 MV and 10 MV x-rays. |
| キーワード | Gafchromic MD-55-2 film radiation dose build-up build-down glottic cancer |
| 出版物タイトル | 岡山大学医学部保健学科紀要 |
| 発行日 | 2002-03-20 |
| 巻 | 12巻 |
| 号 | 2号 |
| 開始ページ | 91 |
| 終了ページ | 99 |
| ISSN | 1345-0948 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002307342 |