検索結果 - 岡山大学学術成果リポジトリ

Twist Knot: A New Sliding Noose in Adjustable Suture Strabismus Surgery

JaLCDOI	10.18926/AMO/57378
フルテキストURL	73_5_463.pdf
著者	Shibata, Kiyo\| Hamasaki, Ichiro\| Shimizu, Takehiro\| Kono, Reika\| Ohtsuki, Hiroshi\| Morizane, Yuki\| Shiraga, Fumio\|
抄録	To permit noose movement without fraying the sutures following strabismus surgery, we designed a new sliding noose, the “twist knot” and investigated its advantages and disadvantages. We measured the tensile strength required to move the twist knot in a tightly tied state (134±19 gf) and in a loosened state (21±7 gf), and that required to move the conventional sliding noose in a tightly tied state (48±14 gf), and used the Kruskal-Wallis test to compare them. A significant difference was observed among the three tensile strengths (p<0.001). The twist knot technique allowed easy sliding without the multifilament braided suture becoming frayed and a knot to be firmly fixed without slipping. However, if the 2 strings of the pole sutures exit from the sclera at 2 widely separated positions, the sliding noose may become slack. Therefore, the distance between the pole sutures should be small. The simple twist knot technique was found to be an effective approach following adjustable surgery of strabismus.
キーワード	adjustable suture the new sliding noose method tensile strength strabismus surgery esotropia
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	463
終了ページ	468
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649374
Web of Science KeyUT	000491886600013

Developing Microsurgery through Experience in Yangon General Hospital, Myanmar

JaLCDOI	10.18926/AMO/57369
フルテキストURL	73_5_393.pdf
著者	Yi Yi Cho Thein\| Win, Myitzu\| Thuzara, Moe\| Matsumoto, Hiroshi\| Yamada, Kiyoshi\| Kimata, Yoshihiro\| Leung, Michael\|
抄録	Although many surgical centers perform microsurgery routinely in developed countries, performing microsurgery is challenging in resource-poor developing countries, such as Myanmar. With the establishment of educational training programs and the assistance of volunteer plastic surgical teams, local plastic surgeons can learn the techniques of microsurgery and apply them clinically. The purpose of this study was to establish baseline data and define the challenges of performing microsurgery in Yangon General Hospital, Myanmar. Sixty-four patients underwent reconstruction with free flaps from January 2015 to January 2018. All clinical records of these cases were assessed. The number of free flap reconstructions performed increased from 11 in the first year to 24 in the third year. The anterolateral thigh flap was the most commonly used (42%). The most common sites of reconstruction were mandible and intraoral defects. Total flap survival occurred in 58 of 64 patients (89%). The total salvageable flap rate for revision surgery was 66.6%; the successful revision rate was highest in 2017, with fewer complications. The flap salvage rates increased and the operative duration decreased as clinical experience improved. Establishing a microsurgical center requires a strong multidisciplinary team, clinical experience, continuous learning, sensible clinical application, and effective interdepartmental and intradepartmental cooperation.
キーワード	microsurgery educational programs challenges of microsurgical free flaps reoperation flap salvageable rate
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	393
終了ページ	401
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649365
Web of Science KeyUT	000491886600004

Impact of Disease Complexity on Cardiovascular Events after the Transition to an Adult Congenital Heart Disease Specialized Medical Unit

JaLCDOI	10.18926/AMO/56932
フルテキストURL	73_4_307.pdf
著者	Takahashi, Sho\| Akagi, Teiji\| Toh, Norihisa\| Takaya, Yoichi\| Nakagawa, Koji\| Nishii, Nobuhiro\| Ito, Hiroshi\|
抄録	The follow-up of patients with adult congenital heart disease (ACHD) at a specialized medical unit is necessary for the patients’ appropriate medical care. However, limited information is available about cardiovascular events among ACHD patients. Here we investigated the type and frequency of cardiovascular events in ACHD patients in relation to disease complexity. We retrospectively analyzed the cases of 535 patients (median age 35 years) referred to our ACHD center between 2014 and 2017. We divided the patients into 3 groups based on their disease complexity. To evaluate the relationship between disease complexity and cardiovascular events, we performed univariate and multivariate survival analyses. The Simple, moderate, and complex disease groups accounted for 62%, 19%, and 19% of the patients, respectively. Apart from events related to atrial septal defect (ASD) trans-catheter treatment, the frequency of cardiovascular events was dependent on the disease complexity (event-free survival rates at 3 years were 85%, 65%, and 58%, respectively). The hazard ratios were 4.0 and 5.1 in the moderate and complex groups, respectively. With the exception of scheduled transcatheter intervention, cardiovascular events were strongly related to the disease complexity of original heart disease. However, cardiovascular events were not rare even in the simple ACHD group.
キーワード	congenital heart defect congenital in adults hospitalization cardiovascular event
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-08
巻	73巻
号	4号
出版者	Okayama University Medical School
開始ページ	307
終了ページ	313
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31439953

Improvement of Open Bite and Stomatognathic Function in an Axenfeld- Rieger Syndrome Patient by Orthodontic Sectional Arch Mechanics: Clinical Considerations and the Risk of Orthodontic Tooth Movement

JaLCDOI	10.18926/AMO/56869
フルテキストURL	73_3_255.pdf
著者	Seki, Daisuke\| Takeshita, Nobuo\| Seiryu, Masahiro\| Deguchi, Toru\| Takano-Yamamoto, Teruko\|
抄録	Orthodontists need to understand the orthodontic risks associated with systemic disorders. Axenfeld-Rieger syndrome (ARS) is a rare autosomal dominant disorder with genetic and morphological variability. The risks of orthodontic treatment in ARS patients have been unclear. Here we describe the correction of an anterior open bite in a 15-year-old Japanese female ARS patient by molar intrusion using sectional archwires with miniscrew implants. An undesirable development of external apical root resorption (EARR) was observed in all intrusive force-applied posterior teeth during the patient’s orthodontic treatment, suggesting that ARS patients have a higher risk of EARR than the general population.
キーワード	Axenfeld-Rieger syndrome external apical root resorption miniscrew implant anterior open bite
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2019-06
巻	73巻
号	3号
出版者	Okayama University Medical School
開始ページ	255
終了ページ	262
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31235974

Prevalence of and Risk Factors for the Progression of Upper Cervical Lesions in Patients with Rheumatoid Arthritis

JaLCDOI	10.18926/AMO/56866
フルテキストURL	73_3_235.pdf
著者	Horita, Masahiro\| Nishida, Keiichiro\| Hashizume, Kenzo\| Sugimoto, Yoshihisa\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Harada, Ryozo\| Ozaki, Toshifumi\|
抄録	We investigated the prevalence of and risk factors for the progression of upper cervical lesions (UCLs) in patients with rheumatoid arthritis (RA). A retrospective analysis of 49 patients with RA (4 males, 45 females) was conducted. The UCLs included atlanto-axial subluxation and vertical subluxation. We investigated the clinical factors including the Disease Activity Score 28 based on C-reactive protein (DAS28-CRP) and the modified Health Assessment Questionnaire-Disability Index as well as radiographic changes between the baseline (at May 2010 to April 2013) and final follow-up. Forty patients (81.6%) were classified as the non-progressive group, and the other 9 patients (18.4%) comprised the progressive group. The progressive group’s final CRP values, baseline or final MMP-3 levels, DAS28-CRP, and rate of pre-existing lesions at baseline were all significantly higher than those of the non-progressive group (p=0.017, p=0.043, p=0.002, p=0.008, p<0.001, and p=0.008 respectively). A multivariate logistic regression analysis demonstrated that DAS28-CRP at baseline was a risk factor for radiographic progression (p=0.018, odds ratio: 2.54, 95% confidence interval: 1.17-5.51). Our findings indicate that higher disease activity might influence the progression of UCLs in patients with RA.
キーワード	rheumatoid arthritis upper cervical spine lesion risk factor radiological progression
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-06
巻	73巻
号	3号
出版者	Okayama University Medical School
開始ページ	235
終了ページ	240
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31235971

Spiral Trajectory Modulation of Rheotaxic Motile Human Sperm in Cylindrical Microfluidic Channels of Different Inner Diameters

JaLCDOI	10.18926/AMO/56863
フルテキストURL	73_3_213.pdf
著者	Nishina, Saori\| Matsuura, Koji\| Naruse, Keiji\|
抄録	We investigated the relationship between human sperm rheotaxis and motile sperm trajectories by using poly-(dimethylsiloxane) (PDMS)-based cylindrical microfluidic channels with inner diameters of 100 μm, 50 μm, and 70 μm, which corresponded to the inner diameter of the human isthmus, the length of a sperm and a diameter intermediate between the two, respectively. We counted the number of rheotaxic sperm and sperm with spiral motion. We also analyzed motile sperm trajectories. As the cylindrical channel diameter was decreased, the percentage of sperm cells exhibiting rheotaxis, the percentage of sperm cells exhibiting spiral motion, the frequency-to-diameter ratio of the sperm cells’ spiral trajectories, and the surface area of the microfluidic channel increased, while the flagellar motion at the channel wall decreased. The percentage of sperm exhibiting a spiral trajectory and the frequency-to-diameter ratio of the sperm cells’ spiral trajectories were thus affected by the channel diameter. Our findings suggest that the oviduct structure affects the swimming properties of sperm cells, guiding them from the uterus to the ampulla for egg fertilization. These results could contribute to the development of motile sperm-sorting microfluidic devices for assisted reproductive technologies.
キーワード	sperm motility trajectory microfluidic channel rheotaxis oviduct structure
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-06
巻	73巻
号	3号
出版者	Okayama University Medical School
開始ページ	213
終了ページ	221
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31235968

Efficacy of Oral Care Provided by Interprofessional Collaboration for a Patient with Esophageal Cancer Associated with Post-polio Syndrome during Neoadjuvant Chemotherapy

JaLCDOI	10.18926/AMO/56461
フルテキストURL	73_1_71.pdf
著者	Takahashi-Arimasa, Keiko\| Kohno-Yamanaka, Reiko\| Soga, Yoshihiko\| Miura, Rumi\| Morita, Manabu\|
抄録	Preoperative oral care is helpful to prevent postoperative complications in patients who are undergoing esophagectomy. Here, we report the case of an 81-year-old Japanese man with an upper limb disability caused by post-polio syndrome who was receiving neoadjuvant chemotherapy for esophageal cancer. He had poor oral health status and developed oral complications as a side effect of chemotherapy. He could not brush his teeth by himself. However, infection control by oral care provided by an interprofessional collaboration successfully improved his oral hygiene, and his follow-up involved no severe complications. Interprofessional collaboration is useful especially for patients with upper limb disability.
キーワード	esophageal cancer preoperative oral care post-polio syndrome neoadjuvant chemotherapy oral mucositis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2019-02
巻	73巻
号	1号
出版者	Okayama University Medical School
開始ページ	71
終了ページ	76
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	30820057

Congenital Multiple Ocular Motor Nerve Palsy Complicated by Splitting of the Lateral Rectus Muscle

JaLCDOI	10.18926/AMO/56460
フルテキストURL	73_1_67.pdf
著者	Kono, Reika\| Shimizu, Takehiro\| Ohtsuki, Hiroshi\| Hamasaki, Ichiro\| Shibata, Kiyo\| Kishimoto, Fumiko\| Morizane, Yuki\| Shiraga, Fumio\|
抄録	We report a case of congenital multiple ocular motor nerve palsy combined with splitting of the lateral rectus muscle (LR). A 59-year-old Japanese female was investigated for worsening esotropia after corrective surgery. She presented with left hypertropia (35Δ) and esotropia (45-50Δ). Orbital magnetic resonance imaging (MRI) showed reduced belly sizes in the superior rectus, inferior rectus, and superior oblique muscles and splitting of the LR, extending from the origin to the belly, in the left eye. Splitting of the LR belly was detected on MRI in a case of congenital multiple ocular motor nerve palsy.
キーワード	multiple ocular motor nerve palsy congenital cranial dysinnervation disorder lateral rectus muscle splitting orbital connective tissue magnetic resonance imaging
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2019-02
巻	73巻
号	1号
出版者	Okayama University Medical School
開始ページ	67
終了ページ	70
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	30820056

Induction of IL-17 production from human peripheral blood CD4+ cells by asbestos exposure

フルテキストURL	ijo_50_6_2024.pdf
著者	Maeda, Megumi\| Chen, Ying\| Lee, Suni\| Kumagai-Takei, Naoko\| Yoshitome, Kei\| Matsuzaki, Hidenori\| Yamamoto, Shoko\| Hatayama, Tamayo\| Ikeda, Miho\| Nishimura, Yasumitsu\| Otsuki, Takemi\|
備考	This is an article published by Spandidos Publications\| This fulltext availavle in Nov 2017\|
発行日	2017-05-09
出版物タイトル	International Journal of Oncology
巻	50巻
号	6号
出版者	Spandidos
開始ページ	2024
終了ページ	2032
ISSN	1019-6439
NCID	AA10992511
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン	publisher
PubMed ID	28498408
DOI	10.3892/ijo.2017.3991
Web of Science KeyUT	000402692100010
関連URL	https://doi.org/10.3892/ijo.2017.3991

3 年間の内視鏡所見の変化を観察できた食道異所性皮脂腺の1 例

著者	岩室雅也\| 岡田裕之\| 原田馨太\| 神崎洋光\| 堀圭介\| 喜多雅英\| 川野誠司\| 河原祥朗\| 田中健大\| 山本和秀\|
発行日	2016-12-01
出版物タイトル	岡山医学会雑誌
巻	128巻
号	3号
資料タイプ	学術雑誌論文

プレガバリン内服困難となった後にリドカイン塩酸塩静注が奏功した転移性癌浸潤による神経障害性疼痛の一例

著者	國末充央\|
発行日	2016-12-01
出版物タイトル	岡山医学会雑誌
巻	128巻
号	3号
資料タイプ	学術雑誌論文

Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases

フルテキストURL	K0005390_abstract_review.pdf K0005390_fulltext.pdf
著者	磯崎英子\|
発行日	2016-06-30
資料タイプ	学位論文
学位授与番号	甲第5390号
学位授与年月日	2016-06-30
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

拡大内視鏡検査にて形態変化を観察しえた十二指腸濾胞性リンパ腫の1例

タイトル（別表記）	Magnified observation of spontaneous morphological changes of duodenal follicular lymphoma
フルテキストURL	128_111.pdf
著者	岩室雅也\| 高田尚良\| 川野誠司\| 河原祥朗\| 吉野正\| 岡田裕之\|
抄録	A 63-year-old Japanese woman was diagnosed with duodenal follicular lymphoma. The initial esophagogastroduodenoscopic examination with magnifying observation revealed opaque white spots and enlarged whitish villi. Nine months later, esophagogastroduodenoscopy showed that the size of the lymphoma lesion decreased, and only opaque white spots were visible. The histological analysis of biopsy samples obtained during the initial endoscopy examination showed both neoplastic follicles and an inter-follicular infiltration of lymphoma cells, whereas the biopsy samples obtained at the endoscopy performed 9 months later showed only neoplastic follicle formation. These results suggest that the magnifying endoscopic features may reflect the underlying pathological mechanisms : enlarged whitish villi are probably due to lymphoma cell infiltration in the inter-follicular area, and opaque white spots are probably caused by neoplastic follicle formation.
キーワード	消化管原発濾胞性リンパ腫（primary gastrointestinal follicular lymphoma）悪性リンパ腫（malignant lymphoma）拡大内視鏡検査（magnifying endoscopy）
出版物タイトル	岡山医学会雑誌
発行日	2016-08-01
巻	128巻
号	2号
開始ページ	111
終了ページ	116
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.128.111
言語	日本語
著作権者	Copyright (c) 2016 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.128.111
NAID	130005262531

「土産写真帖」に見る植民地「ビルマ」のイメージ

著者	渡邊佳成\|
発行日	2016-03-31
出版物タイトル	岡山大学文学部プロジェクト研究報告書
巻	23巻
資料タイプ	研究報告書

出現するほとけ―密教経企軌の記載を中心に

著者	佐々木守俊\|
発行日	2016-03-31
出版物タイトル	岡山大学文学部プロジェクト研究報告書
巻	23巻
資料タイプ	研究報告書

Structure of a New Palatal Plate and the Artificial Tongue for Articulation Disorder in a Patient with Subtotal Glossectomy

JaLCDOI	10.18926/AMO/54420
フルテキストURL	70_3_205.pdf
著者	Kozaki, Ken-ichi\| Kawakami, Shigehisa\| Konishi, Takayuki\| Ohta, Keiji\| Yano, Jitsuro\| Onoda, Tomoo\| Matsumoto, Hiroshi\| Mizukawa, Nobuyoshi\| Kimata, Yoshihiro\| Nishizaki, Kazunori\| Iida, Seiji\| Gofuku, Akio\| Abe, Masanobu\| Minagi, Shogo\| Okayama Dream Speech Project\|
抄録	A palatal augmentation prosthesis (PAP) is used to facilitate improvement in the speech and swallowing functions of patients with tongue resection or tongue movement disorders. However, a PAPʼs effect is limited in cases where articulation disorder is severe due to wide glossectomy and/or segmental mandibulectomy. In this paper, we describe speech outcomes of a patient with an articulation disorder following glossectomy and segmental mandibulectomy. We used a palatal plate (PP) based on a PAP, along with an artificial tongue (KAT). Speech improvement was evaluated by a standardized speech intelligibility test consisting of 100 syllables. The speech intelligibility score was significantly higher when the patient wore both the PP and KAT than when he wore neither (p＝0.013). The conversational intelligibility score was significantly improved with the PP and KAT than without PP and KAT (p＝0.024). These results suggest that speech function can be improved in patients with hard tissue defects with segmental mandibulectomy using both a PP and a KAT. The nature of the design of the PP and that of the KAT will allow these prostheses to address a wide range of tissue defects.
キーワード	palatal augmentation prosthesis artificial tongue articulation disorder glossectomy mandibulectomy
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2016-06
巻	70巻
号	3号
出版者	Okayama University Medical School
開始ページ	205
終了ページ	211
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	27339210
Web of Science KeyUT	000379406100008

Identification of cell surface markers from multidimensional microarray data utilizing spherical Self Organizing Maps

フルテキストURL	K0005335_abstract_review.pdf K0005335_fulltext.pdf
著者	杉井裕\|
発行日	2016-03-25
資料タイプ	学位論文
学位授与番号	甲第5335号
学位授与年月日	2016-03-25
学位・専攻分野	博士（工学）
授与大学	岡山大学
言語	英語

A neutrophil elastase inhibitor improves lung function during ex vivo lung perfusion

フルテキストURL	K0005261_abstract_review.pdf K0005261_fulltext.pdf
著者	原田昌明\|
発行日	2016-03-25
資料タイプ	学位論文
学位授与番号	甲第5261号
学位授与年月日	2016-03-25
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

Hyaluronan suppresses mechanical stress-induced expression of catabolic enzymes by human chondrocytes via inhibition of IL-1β production and subsequent NF-κB activation

フルテキストURL	K0005198_abstract_review.pdf K0005198_fulltext.pdf
著者	小澤正嗣\|
発行日	2015-06-30
資料タイプ	学位論文
学位授与番号	甲第5198号
学位授与年月日	2015-06-30
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

平成26年度岡山医学会賞がん研究奨励賞（林原賞・山田賞）

タイトル（別表記）	The 2014 Incentive Award of the Okayama Medical Association in Cancer Research (2014 Hayashibara Prize and Yamada Prize)
フルテキストURL	127_91.pdf
著者	矢野修也\|
出版物タイトル	岡山医学会雑誌
発行日	2015-08-03
巻	127巻
号	2号
開始ページ	91
終了ページ	94
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.127.91
言語	日本語
著作権者	Copyright (c) 2015 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.127.91
NAID	130005096248