検索結果 - 岡山大学学術成果リポジトリ

The preoperative flexion tear gap affects postoperative meniscus stability after pullout repair for medial meniscus posterior root tear

フルテキストURL	fulltext.pdf
著者	Tamura, Masanori\| Furumatsu, Takayuki\| Kitayama, Takahiro\| Yokoyama, Yusuke\| Okazaki, Yuki\| Kawada, Koki\| Ozaki, Toshifumi\|
キーワード	Medial meniscus Posterior root tear Distance Pullout repair Second-look arthroscopy
発行日	2025-04-03
出版物タイトル	Knee Surgery & Related Research
巻	37巻
号	1号
出版者	Springer Nature
開始ページ	16
ISSN	2234-2451
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
PubMed ID	40181486
DOI	10.1186/s43019-025-00264-7
Web of Science KeyUT	001459123500001
関連URL	isVersionOf https://doi.org/10.1186/s43019-025-00264-7

Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography

フルテキストURL	fulltext.pdf
著者	Ohata, Miyu\| Fukui, Ryohei\| Morimitsu, Yusuke\| Kobayashi, Daichi\| Yamauchi, Takatsugu\| Akagi, Noriaki\| Honda, Mitsugi\| Hayashi, Aiko\| Hasegawa, Koshi\| Kida, Katsuhiro\| Goto, Sachiko\| Hiraki, Takao\|
キーワード	Image quality photon-counting computed tomography quantum iterative reconstruction radiomics renal cell carcinoma
発行日	2025-01
出版物タイトル	Journal of Medical Physics
巻	50巻
号	1号
出版者	Medknow Publications
開始ページ	100
終了ページ	107
ISSN	0971-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Journal of Medical Physics
論文のバージョン	publisher
DOI	10.4103/jmp.jmp_114_24
Web of Science KeyUT	001452585400015
関連URL	isVersionOf https://doi.org/10.4103/jmp.jmp_114_24

Roles of basic amino acid residues in substrate binding and transport of the light-driven anion pump Synechocystis halorhodopsin (SyHR)

フルテキストURL	fulltext.pdf
著者	Nakama, Masaki\| Noji, Tomoyasu\| Kojima, Keiichi\| Yoshizawa, Susumu\| Ishikita, Hiroshi\| Sudo, Yuki\|
キーワード	microbial rhodopsin anion transport retinal membrane protein photobiology
発行日	2025-04
出版物タイトル	Journal of Biological Chemistry
巻	301巻
号	4号
出版者	Elsevier
開始ページ	108334
ISSN	1083-351X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Authors.
論文のバージョン	publisher
PubMed ID	39984052
DOI	10.1016/j.jbc.2025.108334
Web of Science KeyUT	001450594900001
関連URL	isVersionOf https://doi.org/10.1016/j.jbc.2025.108334

Robustness of Machine Learning Predictions for Determining Whether Deep Inspiration Breath-Hold Is Required in Breast Cancer Radiation Therapy

フルテキストURL	fulltext.pdf
著者	Al-Hammad, Wlla E.\| Kuroda, Masahiro\| Al Jamal, Jamal, Ghaida\| Fujikura, Mamiko\| Kamizaki, Ryo\| Kuroda, Kazuhiro\| Yoshida, Suzuka\| Nakamura, Yoshihide\| Oita, Masataka\| Tanabe, Yoshinori\| Sugimoto, Kohei\| Sugianto, Irfan\| Barham, Majd\| Tekiki, Nouha\| Hisatomi, Miki\| Asaumi, Junichi\|
キーワード	breast cancer radiation therapy heart dose cut-off value machine learning robustness instability F2 score deep inspiration breath-hold technique computed tomography
発行日	2025-03-10
出版物タイトル	Diagnostics
巻	15巻
号	6号
出版者	MDPI
開始ページ	668
ISSN	2075-4418
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	40150011
DOI	10.3390/diagnostics15060668
Web of Science KeyUT	001452220400001
関連URL	isVersionOf https://doi.org/10.3390/diagnostics15060668

A glucocorticoid-regulating molecule, Fkbp5, may interact with mitogen-activated protein kinase signaling in the organ of Corti of mice cochleae

フルテキストURL	fulltext.pdf
著者	Sato, Asuka\| Omichi, Ryotaro\| Maeda, Yukihide\| Ando, Mizuo\|
キーワード	The organ of Corti Acoustic trauma RNA sequencing 51-Da FK506-binding protein Mitogen-activated protein kinase signaling Tumor necrosis factor signaling
発行日	2025-03-03
出版物タイトル	Scientific Reports
巻	15巻
号	1号
出版者	Nature Portfolio
開始ページ	7506
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	40033010
DOI	10.1038/s41598-025-92400-2
Web of Science KeyUT	001437310100016
関連URL	isVersionOf https://doi.org/10.1038/s41598-025-92400-2

Changes of leucine-rich alpha 2 glycoprotein could be a marker of changes of endoscopic and histologic activity of ulcerative colitis

フルテキストURL	fulltext.pdf
著者	Aoyama, Yuki\| Hiraoka, Sakiko\| Yasutomi, Eriko\| Inokuchi, Toshihiro\| Tanaka, Takehiro\| Takei, Kensuke\| Igawa, Shoko\| Takeuchi, Keiko\| Takahara, Masahiro\| Toyosawa, Junki\| Yamasaki, Yasushi\| Kinugasa, Hideaki\| Kato, Jun\| Okada, Hiroyuki\| Otsuka, Motoyuki\|
キーワード	Ulcerative colitis Leucine-rich alpha 2 glycoprotein Biomarker
発行日	2025-02-12
出版物タイトル	Scientific Reports
巻	15巻
号	1号
出版者	Nature Portfolio
開始ページ	5248
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39939376
DOI	10.1038/s41598-025-89615-8
Web of Science KeyUT	001421220800034
関連URL	isVersionOf https://doi.org/10.1038/s41598-025-89615-8

Empowering pediatric, adolescent, and young adult patients with cancer utilizing generative AI chatbots to reduce psychological burden and enhance treatment engagement: a pilot study

フルテキストURL	fulltext.pdf
著者	Hasei, Joe\| Hanzawa, Mana\| Nagano, Akihito\| Maeda, Naoko\| Yoshida, Shinichirou\| Endo, Makoto\| Yokoyama, Nobuhiko\| Ochi, Motoharu\| Ishida, Hisashi\| Katayama, Hideki\| Fujiwara, Tomohiro\| Nakata, Eiji\| Nakahara, Ryuichi\| Kunisada, Toshiyuki\| Tsukahara, Hirokazu\| Ozaki, Toshifumi\|
キーワード	generative AI chatbot large language model pediatric cancer adolescent and young adult (AYA) psychological support
発行日	2025-02-25
出版物タイトル	Frontiers in Digital Health
巻	7巻
出版者	Frontiers Media
開始ページ	1543543
ISSN	2673-253X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Hasei, Hanzawa, Nagano, Maeda, Yoshida, Endo, Yokoyama, Ochi, Ishida, Katayama, Fujiwara, Nakata, Nakahara, Kunisada, Tsukahara and Ozaki.
論文のバージョン	publisher
PubMed ID	40070545
DOI	10.3389/fdgth.2025.1543543
Web of Science KeyUT	001441098700001
関連URL	isVersionOf https://doi.org/10.3389/fdgth.2025.1543543

A case of invasive pulmonary aspergillosis associated with clozapine-induced agranulocytosis

フルテキストURL	fulltext.pdf
著者	Yokode, Akiyoshi\| Fujiwara, Masaki\| Terao, Toshiki\| Sakamoto, Shinji\| Yamada, Yuto\| Sato, Ryota\| Mishima, Momoko\| Yada, Yuji\| Matsuoka, Ken-Ichi\| Takaki, Manabu\|
キーワード	clozapine-induced agranulocytosis fungal infections invasive pulmonary aspergillosis schizophrenia
発行日	2025-03-02
出版物タイトル	Psychiatry and Clinical Neurosciences Reports
巻	4巻
号	1号
出版者	Wiley
開始ページ	e70077
ISSN	2769-2558
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
DOI	10.1002/pcn5.70077
Web of Science KeyUT	001435401500001
関連URL	isVersionOf https://doi.org/10.1002/pcn5.70077

Distinct Infection Mechanisms of Rhizoctonia solani AG-1 IA and AG-4 HG-I+II in Brachypodium distachyon and Barley

フルテキストURL	fulltext.pdf
著者	Mahadevan, Niranjan\| Fernanda, Rozi\| Kouzai, Yusuke\| Kohno, Natsuka\| Nagao, Reiko\| Nyein, Khin Thida\| Watanabe, Megumi\| Sakata, Nanami\| Matsui, Hidenori\| Toyoda, Kazuhiro\| Ichinose, Yuki\| Mochida, Keiichi\| Hisano, Hiroshi\| Noutoshi, Yoshiteru\|
キーワード	Rhizoctonia solani species complex virulence mechanism infection behavior salicylic acid N-hydroxypipecolic acid
発行日	2025-02-05
出版物タイトル	Life
巻	15巻
号	2号
出版者	MDPI
開始ページ	235
ISSN	2075-1729
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	40003643
DOI	10.3390/life15020235
Web of Science KeyUT	001431010900001
関連URL	isVersionOf https://doi.org/10.3390/life15020235

An Application of SEMAR IoT Application Server Platform to Drone-Based Wall Inspection System Using AI Model

フルテキストURL	fulltext.pdf
著者	Panduman, Yohanes Yohanie Fridelin\| Husna, Radhiatul\| Noprianto, Nobuo\| Funabiki, Nobuo\| Sakamaki, Shunya\| Sukaridhoto, Sritrusta\| Syaifudin, Yan Watequlis\| Rahmadani, Alfiandi Aulia\|
キーワード	Internet of Things AI SEMAR crack detection drone Kafka
発行日	2025-01-24
出版物タイトル	Information
巻	16巻
号	2号
出版者	MDPI
開始ページ	91
ISSN	2078-2489
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
DOI	10.3390/info16020091
Web of Science KeyUT	001430117200001
関連URL	isVersionOf https://doi.org/10.3390/info16020091

Interrelationships Between Plasma Levels of Brain Natriuretic Peptide and Prolonged Symptoms Due to Long COVID

フルテキストURL	fulltext.pdf
著者	Masuda, Yohei\| Otsuka, Yuki\| Tokumasu, Kazuki\| Honda, Hiroyuki\| Sakurada, Yasue\| Matsuda, Yui\| Nakano, Yasuhiro\| Takase, Ryosuke\| Omura, Daisuke\| Hasegawa, Toru\| Ueda, Keigo\| Otsuka, Fumio\|
キーワード	brain fog brain natriuretic peptide (BNP) COVID-19 fatigue long COVID memory impairment post-COVID-19 conditions
発行日	2025-01-26
出版物タイトル	Journal of Clinical Medicine
巻	14巻
号	3号
出版者	MDPI
開始ページ	817
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	39941487
DOI	10.3390/jcm14030817
Web of Science KeyUT	001420254400001
関連URL	isVersionOf https://doi.org/10.3390/jcm14030817

A capsidless (+)RNA yadokarivirus hosted by a dsRNA virus is infectious as particles, cDNA, and dsRNA

フルテキストURL	fulltext.pdf
著者	Fadli, Muhammad\| Hisano, Sakae\| Novoa, Guy\| Castón, José R.\| Kondo, Hideki\| Suzuki, Nobuhiro\|
キーワード	yadokarivirus hetero-encapsidation partner dsRNA virus fungal virus Aspergillus foetidus neo-lifestyle
発行日	2025-02-13
出版物タイトル	Journal of Virology
巻	99巻
号	3号
出版者	American Society for Microbiology
開始ページ	e02166-24
ISSN	0022-538X
NCID	AA00708779
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Fadli et al.
論文のバージョン	publisher
PubMed ID	39945536
DOI	10.1128/jvi.02166-24
Web of Science KeyUT	001421220200001
関連URL	isVersionOf https://doi.org/10.1128/jvi.02166-24

LRP4 and Agrin Are Modulated by Cartilage Degeneration and Involved in β-Catenin Signaling in Human Articular Chondrocytes

フルテキストURL	fulltext.pdf
著者	Naniwa, Shuichi\| Nishida, Keiichiro\| Yoshida, Aki\| Nasu, Yoshihisa\| Nakahara, Ryuichi\| Ohtsuki, Takashi\| Hotta, Yoshifumi\| Shimizu, Noriyuki\| Ichikawa, Chinatsu\| Lin, Deting\| Otsuka, Noriaki\| Ozaki, Toshifumi\|
キーワード	osteoarthritis chondrocyte mechanical stress LRP4 Agrin β-catenin SOX9
発行日	2025-01-24
出版物タイトル	International Journal of Molecular Sciences
巻	26巻
号	3号
出版者	MDPI
開始ページ	1007
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	39940775
DOI	10.3390/ijms26031007
Web of Science KeyUT	001418599900001
関連URL	isVersionOf https://doi.org/10.3390/ijms26031007

A case of pancreatic ductal adenocarcinoma growing within the pancreatic duct mimicking an intraductal tubulopapillary neoplasm

フルテキストURL	fulltext.pdf
著者	Sato, Ryosuke\| Matsumoto, Kazuyuki\| Uka, Mayu\| Takagi, Kosei\| Nishida, Kenji\| Tanaka, Takehiro\| Fujii, Yuki\| Tsutsumi, Koichiro\| Horiguchi, Shigeru\| Otsuka, Motoyuki\|
キーワード	Pancreatic intraductal neoplasms Pancreatic carcinoma Intraductal tubulopapillary neoplasm Genetic testing
備考	The version of record of this article, first published in Clinical Journal of Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12328-025-02098-y\|
発行日	2025-02-05
出版物タイトル	Clinical Journal of Gastroenterology
巻	18巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	376
終了ページ	382
ISSN	1865-7257
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39910028
DOI	10.1007/s12328-025-02098-y
Web of Science KeyUT	001415187700001
関連URL	isVersionOf https://doi.org/10.1007/s12328-025-02098-y

A Rare Case of Compression Neuritis due to Intraorbital Arteriovenous Fistula (IOAVF) Mimicking Retrobulbar Optic Neuritis

JaLCDOI	10.18926/AMO/68363
フルテキストURL	79_1_059.pdf
著者	Minakawa, Shun\| Hirano, Masayuki\| Takahashi, Kazuya\| Imamura, Yuta\| Watanabe, Takashi\|
抄録	Intraorbital arteriovenous fistulas (IOAVFs) are rare vascular abnormalities. We describe a case of an IOAVF featuring a direct shunt between the accessory meningeal artery and the superior ophthalmic artery. A 55-year-old woman presented with a 1-month history of visual impairment in her right eye, and magnetic resonance imaging (MRI) revealed optic neuritis-like findings. Steroid pulse therapy temporarily resolved visual impairment. However, 1 month later, she experienced decreased visual acuity, ocular conjunctival hyperemia, edema, and a pulsatile murmur. Contrast-enhanced MRI and digital subtraction angiography revealed compression optic neuropathy due to an IOAVF. Following successful treatment with transarterial embolization, her symptoms disappeared.
キーワード	intraorbital arteriovenous fistula compressive optic neuropathy accessory meningeal artery superior ophthalmic vein
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	59
終了ページ	64
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012161
Web of Science KeyUT	001440463800008

Photoinitiators Induce Histamine Production in Human Mast Cells

JaLCDOI	10.18926/AMO/68362
フルテキストURL	79_1_051.pdf
著者	Miura, Taro\| Kawasaki, Yoichi\| Hamano, Hirofumi\| Zamami, Yoshito\| Sendo, Toshiaki\|
抄録	Photoinitiators are used in the manufacture of many daily products, and may produce harmful effects due to their cytotoxicity. They have also been detected in human serum. Here, we investigated the histamine-producing effects in HMC-1 cells and the inflammatory cytokine release effects in RAW264 cells for four photoinitiators: 1-hydroxycyclohexyl phenyl ketone; 2-isopropylthioxanthone; methyl 2-benzoylbenzoate; and 2-methyl-4´-(methylthio)-2-morpholinopropiophenone. All four promoted histamine production in HMC-1 cells; however, they did not significantly affect the release of inflammatory cytokines in RAW264 cells. These findings suggest that these four photoinitiators induce inflammatory cytokine-independent histamine production, potentially contributing to histamine-mediated chronic inflammation in vitro.
キーワード	photoinitiator ink injection histamine inflammation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	51
終了ページ	58
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012160
Web of Science KeyUT	001440463800007

Immediate Effects of a Single Home-based Rehabilitation Treatment on Balance Performance and Toe-Grip Strength in Elderly Subjects Continuing the Same Rehabilitation Program

JaLCDOI	10.18926/AMO/68361
フルテキストURL	79_1_047.pdf
著者	Kojima, Kazunori\| Ujikawa, Takuya\| Ono, Toshiro\|
抄録	We assessed the immediate effects of a home-based rehabilitation (HBR) program on the balance performance and toe-grip strength of 29 older adults (mean±SD age of 75.1±9.9; 16 males, 13 females) who were participating in HBR services provided by Japan’s nursing care insurance system. Their toe-grip strength and balance performance were measured before and after the HBR program. The subjects’ toe-grip strength was significantly improved after the treatment. The subjects who had had a stroke showed a significant improvement after HBR. Contrarily, no significant difference was observed in the subjects’ functional reach results or their one-leg standing time. These results indicate that the exercise regimen provided in the HBR program led to increased excitability of motor units and immediately enhanced the subjects’ toe-grip strength.
キーワード	home-based rehabilitation toe-grip strength balance performance
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	47
終了ページ	50
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012159
Web of Science KeyUT	001440463800006

Could the Trabecular Bone Score Be a Complementary Tool for Evaluating Degenerative Lumbar Vertebrae?

JaLCDOI	10.18926/AMO/68360
フルテキストURL	79_1_039.pdf
著者	Takao, Shinichiro\| Uotani, Koji\| Misawa, Haruo\| Tetsunaga, Tomoko\| Shinohara, Kensuke\| Yamane, Kentaro\| Oda, Yoshiaki\| Tsuji, Hironori\| Kajiki, Yuya\| Ozaki, Toshifumi\|
抄録	Evaluating vertebral bone mass and quality in the elderly poses challenges due to degenerative changes. This study aims to elucidate the usefulness of the trabecular bone score (TBS) by examining the relationship between bone mineral density (BMD), TBS, and Hounsfield unit (HU) values. A retrospective analysis of 599 vertebrae from 152 patients (mean age 69.0 years; range 44-89; 74 males and 78 females) undergoing dual-energy X-ray absorptiometry (DXA) and CT scans was conducted. Vertebrae were categorized into three grades based on the degree of degeneration. The TBS was calculated from DXA images, and the HU value was measured by placing a region of interest on an axial image of the vertebral mid-body. One-way analysis of variance and Pearson’s correlation tests were employed to investigate the relationship between BMD and TBS or HU values. While lumbar BMD significantly increased (p<0.01) with degenerative changes, TBS and HU values showed no significant differences. The correlations between lumbar BMD and TBS values, and between BMD and HU values, were stronger without degenerative changes than with degenerative changes. Significantly different HU values were observed between the right and left sides of severely degenerated vertebrae. Severe degenerative changes, particularly those associated with sclerosis, may impact HU values. TBS exhibits greater potential than HU values as a complementary tool.
キーワード	trabecular bone score computed tomography Hounsfield unit lumbar degenerative change radiodensity
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	39
終了ページ	45
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012158
Web of Science KeyUT	001440463800005

Prediction of Prostate Cancer Grades Using Radiomic Features

JaLCDOI	10.18926/AMO/68355
フルテキストURL	79_1_021.pdf
著者	Yamamoto, Yasuhiro\| Haraguchi, Takafumi\| Matsuda, Kaori\| Okazaki, Yoshio\| Kimoto, Shin\| Tanji, Nozomu\| Matsumoto, Atsushi\| Kobayashi, Yasuyuki\| Mimura, Hidefumi\| Hiraki, Takao\|
抄録	We developed a machine learning model for predicting prostate cancer (PCa) grades using radiomic features of magnetic resonance imaging. 112 patients diagnosed with PCa based on prostate biopsy between January 2014 and December 2021 were evaluated. Logistic regression was used to construct two prediction models, one using radiomic features and prostate-specific antigen (PSA) values (Radiomics model) and the other Prostate Imaging-Reporting and Data System (PI-RADS) scores and PSA values (PI-RADS model), to differentiate high-grade (Gleason score [GS] ≥ 8) from intermediate or low-grade (GS < 8) PCa. Five imaging features were selected for the Radiomics model using the Gini coefficient. Model performance was evaluated using AUC, sensitivity, and specificity. The models were compared by leave-one-out cross-validation with Ridge regularization. Furthermore, the Radiomics model was evaluated using the holdout method and represented by a nomogram. The AUC of the Radiomics and PI-RADS models differed significantly (0.799, 95% CI: 0.712-0.869; and 0.710, 95% CI: 0.617-0.792, respectively). Using holdout method, the Radiomics model yielded AUC of 0.778 (95% CI: 0.552-0.925), sensitivity of 0.769, and specificity of 0.778. It outperformed the PI-RADS model and could be useful in predicting PCa grades, potentially aiding in determining appropriate treatment approaches in PCa patients.
キーワード	prostate cancer machine learning prostate Imaging-Reporting and Data System radiomics Gleason score
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	21
終了ページ	30
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012156
Web of Science KeyUT	001440463800003

Gastrectomy Causes an Imbalance in the Trunk Muscles

JaLCDOI	10.18926/AMO/68354
フルテキストURL	79_1_009.pdf
著者	Ikeya, Nanami\| Okita, Atsushi\| Hashida, Shinsuke\| Yamamoto, Sumiharu\| Ikeda, Hirokuni\| Tsukuda, Kazunori\| Toyooka, Shinichi\|
抄録	Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy.
キーワード	sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	9
終了ページ	19
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012155
Web of Science KeyUT	001440463800002