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著者 津下 充|
発行日 2010-12-31
出版物タイトル
資料タイプ 学位論文
著者 髙岩 正典|
発行日 2010-12-31
出版物タイトル
資料タイプ 学位論文
著者 吉川 賢| 井上 正樹| 吉森 一道| 中島 敦司| 寺南 智弘| 松尾 奈緒子| 萬城 遼| 宮本 千晴|
発行日 2011-02-01
出版物タイトル 岡山大学農学部学術報告
100巻
資料タイプ 紀要論文
著者 山中 正仁| 後藤 丹十郎| 東浦 優|
発行日 2011-02-01
出版物タイトル 岡山大学農学部学術報告
100巻
資料タイプ 紀要論文
著者 後藤 丹十郎| 石井 真由美| 藤原 一毅|
発行日 2011-02-01
出版物タイトル 岡山大学農学部学術報告
100巻
資料タイプ 紀要論文
著者 吉田 裕一| 廣瀬 泰久| 森本 由香里| 後藤 丹十郎|
発行日 2011-02-01
出版物タイトル 岡山大学農学部学術報告
100巻
資料タイプ 紀要論文
著者 前村 知美| 内富 久美子| 日下 知香| 稲垣 純子| 田村 隆| 左右田 健次| 稲垣 賢二|
発行日 2011-02-01
出版物タイトル 岡山大学農学部学術報告
100巻
資料タイプ 紀要論文
JaLCDOI 10.18926/AMO/43832
フルテキストURL 65_1_59.pdf
著者 Yasuhara, Takao| Miyoshi, Yasuyuki| Date, Isao|
抄録 A case of a Chiari malformation with an extraordinarily thick occipital bone is described. The thick occipital bone might make the posterior fossa narrow with consequent herniation of the cerebellar tonsils to the foramen magnum and formation of a syrinx. At dural plasty, well-developed marginal and occipital sinuses should be deliberately handled with the preservation of normal venous drainage. This case gives us the essence of the occurrence mechanisms of Chiari malformation and foramen magnum decompression.
キーワード Chiari malformation dural plasty foramen magnum decompression syrinx venous drainage
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2011-02
65巻
1号
出版者 Okayama University Medical School
開始ページ 59
終了ページ 61
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339798
Web of Science KeyUT 000287620500009
JaLCDOI 10.18926/AMO/43830
フルテキストURL 65_1_49.pdf
著者 Iguchi, Toshihiro| Idani, Hitoshi| Asami, Shinya| Endo, Hisashi| Inaba, Yoshitaka| Arai, Yasuaki| Kanazawa, Susumu|
抄録 We administered hepatic arterial infusion chemotherapy (HAIC) prior to FOLFOX to three patients with unresectable liver metastases from colorectal cancer. The patients' disease state was found to be highly advanced based on both computed tomography findings and liver function tests. The treatment strategy included an initial administration of HAIC to control liver metastases and improve liver function in order to facilitate the subsequent safe administration of FOLFOX without drug loss. As the HAIC regimen, 1,000mg/m2 of 5-FU was administered weekly by continuous 5-h infusion after performing laboratory investigations through an implanted port-catheter system. After 3 HAIC cycles administered over 3 consecutive weeks, the mean alkaline phosphatase levels decreased from 969.3IU/l to 422IU/l due to shrinkage of the liver metastases. Thereafter, FOLFOX without drug loss could be safely initiated for all patients. Two patients succumbed 488 and 333 days after HAIC was initiated;the third patient is still alive and has been followed-up for 1215 days. The combined use of HAIC and standard systemic chemotherapy could be a feasible and efficacious treatment in highly advanced cases of liver dysfunction.
キーワード colorectal cancer hepatic arterial infusion chemotherapy liver metastasis port-catheter system
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2011-02
65巻
1号
出版者 Okayama University Medical School
開始ページ 49
終了ページ 53
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339796
Web of Science KeyUT 000287620500007
JaLCDOI 10.18926/AMO/43829
フルテキストURL 65_1_41.pdf
著者 Tokumori, Kimihiko| Wang, Da-Hong| Takigawa, Tomoko| Takaki, Jiro| Ogino, Keiki|
抄録 This study aimed to determine whether there was any association between the regional climate and the proportion of people with joint pain. Regional climate data between 1971 and 2000 were obtained from the Japan Meteorological Agency. The variables used in the cluster analysis included sunlight hours, amount of precipitation, number of days with precipitation, and temperature. The regional proportion of people with joint pain was obtained from the National Survey for Health in 2001. After performing a cluster analysis, one-way ANOVA and Welch's test were used to determine whether the climate characteristics of the clusters were significantly different. Within each cluster, stepwise multiple linear regression analyses were performed. We found that sunlight hours showed a direct, negative association with the proportion of people with joint pain (adjusted R2=0.532, p=0.016) in cluster 1, which was characterized as the region with the fewest total hours of sunlight, less precipitation, a modest number of rainy days, and low temperature. In the other clusters, the regional female population rate (cluster 2) and the senior population rate (cluster 3, 4) were the primary predictors. We concluded that the degree of exposure to sunlight may play a crucial role in prevention of joint pain. This finding should encourage people to set aside some time for staying outdoors in their daily lives.
キーワード climate joint pain sunlight hours cluster analysis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-02
65巻
1号
出版者 Okayama University Medical School
開始ページ 41
終了ページ 48
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339795
Web of Science KeyUT 000287620500006
JaLCDOI 10.18926/AMO/43827
フルテキストURL 65_1_27.pdf
著者 Togami, Taro| Yamamoto, Yuka| Satoh, Katashi| Kameyama, Reiko| Murota, Makiko| Kimura, Naruhide| Nishiyama, Yoshihiro|
抄録 We performed a retrospective study examining the prevalence and subtypes of pulmonary emphysema (PE) identified by computed tomography (CT) in females. We reviewed the records of 1,687 female subjects who had undergone CT. They were divided into the following 2 age groups:group A (<50 years) and group B (>_50 years). PE was diagnosed by the presence of low-attenuation areas using visual assessment (grades 0-3) on CT images. Two subtypes of PE were observed:centrilobular emphysema (CLE) and paraseptal emphysema (PSE). PE was divided into the following 3 categories:I (CLE or CLE-predominant);II (CLE and PSE of equal extent);and III (PSE or PSE-predominant). PE was found in 64 of 274 smokers (23.3%) and 54 of 1,413 non-smokers (3.8%). In smoking subjects, when grades 1 and 2 were grouped together as mild PE, the mean age for CT grade 3 (severe PE) was significantly higher than that for mild PE. In group A, category III predominated, whereas category I was more prevalent in group B, in both smoking and non-smoking subjects. A high incidence of PE was found in smoking subjects as compared with non-smoking subjects. PSE predominated in younger subjects, whereas CLE predominated in older subjects.
キーワード cigarette smoking CT pulmonary emphysema females
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-02
65巻
1号
出版者 Okayama University Medical School
開始ページ 27
終了ページ 32
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339793
Web of Science KeyUT 000287620500004
JaLCDOI 10.18926/AMO/43825
フルテキストURL 65_1_11.pdf
著者 Kuwaki, Kenji| Nouso, Kazuhiro| Kobayashi, Yoshiyuki| Nakamura, Shinichiro| Ito, Yoichi M.| Iwadou, Shouta| Hagihara, Hiroaki| Yasunaka, Tetsuya| Toshimori, Junichi| Miyatake, Hirokazu| Miyoshi, Kenji| Onishi, Hideki| Miyake, Yasuhiro| Shoji, Bon| Takaki, Akinobu| Shiraha, Hidenori| Iwasaki, Yoshiaki| Kobashi, Haruhiko| Yamamoto, Kazuhide|
抄録 The purpose of this study was to build a prognostic model of hepatocellular carcinoma (HCC) using time-dependent covariates to re-evaluate the prognosis at any stage of the disease. The subjects were consecutive HCC patients who were treated at our institute between 1995 and 2007. We constructed time-fixed and time-dependent prognostic models with a training group (n=336) and compared the prognostic abilities between conventional Cancer of the Liver Italian Program (CLIP) scores, Japan Integrated Staging (JIS) scores, an Okuda classification, and our prognostic models in the testing group (n=227) with the c-index. The time-dependent prognostic model consisted of main tumor size, tumor number, portal vein invasion, distant metastasis, alpha-fetoprotein, des-gamma-carboxy prothrombin (DCP), bilirubin, and albumin and the weighted scores were set for each factor depending on the hazard ratio for the prognosis. The prognostic index was determined by summing the scores. The c-index values for the CLIP scores, JIS scores, Okuda classification, and our time-dependent model were 0.741, 0.727, 0.609, and 0.870, respectively. These results indicate that our time-dependent model can estimate the prognosis of HCC more precisely than traditional time-fixed models and can be used to re-predict the prognosis of HCC.
キーワード hepatocellular carcinoma humans prognosis proportional hazards models time factors
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-02
65巻
1号
出版者 Okayama University Medical School
開始ページ 11
終了ページ 19
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339791
Web of Science KeyUT 000287620500002
JaLCDOI 10.18926/AMO/43824
フルテキストURL 65_1_1.pdf
著者 Han, Xiao-Jian| Tomizawa, Kazuhito| Fujimura, Atsushi| Ohmori, Iori| Nishiki, Tei-ichi| Matsushita, Masayuki| Matsui, Hideki|
抄録 Mitochondria are important cellular organelles in most metabolic processes and have a highly dynamic nature, undergoing frequent fission and fusion. The dynamic balance between fission and fusion plays critical roles in mitochondrial functions. In recent studies, several large GTPases have been identified as key molecular factors in mitochondrial fission and fusion. Moreover, the posttranslational modifications of these large GTPases, including phosphorylation, ubiquitination and SUMOylation, have been shown to be involved in the regulation of mitochondrial dynamics. Neurons are particularly sensitive and vulnerable to any abnormalities in mitochondrial dynamics, due to their large energy demand and long extended processes. Emerging evidences have thus indicated a strong linkage between mitochondria and neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and Huntington's disease. In this review, we will describe the regulation of mitochondrial dynamics and its role in neurodegenerative diseases.
キーワード mitochondria phosphorylation ubiquitination SUMOylation neurodegeneration
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2011-02
65巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 10
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21339790
Web of Science KeyUT 000287620500001
著者 且原 真木| 田中丸 重美| 森 泉| 谷 明生| 宇都木 繁子| 榎本 敬| 米谷 俊彦|
発行日 2009-12
出版物タイトル 環境制御
31巻
資料タイプ 紀要論文
JaLCDOI 10.18926/ESR/42460
タイトル(別表記) Representation of Earth scientific information by the Google(TM) Earth
フルテキストURL esr_017_025_026.pdf
著者 山川 純次| 海老 貴宏| 松本 宏文|
抄録 The Google(TM) Earth is a GIS application provided by the Google, with versatile and high performance visualization and manipulation capability for geographic information. The Google Earth is also a multi-platform application, so the installation and running cost for research and education site is relatively low. The Earth scientific information also have a geographic information scheme, so the Google Earth has some potential to support the education and research field of the Earth science. In this report, some Earth scientific information were converted by the R-Language and its libraries for represent by the Google Earth. The 3-dimensional representation of the information will be able to support to understanding the specification of the data for the Earth scientific research and education field.
キーワード Earth scientific information GIS Google Earth Kriging R-Language
出版物タイトル Okayama University Earth Science Report
発行日 2010-12-24
17巻
1号
開始ページ 25
終了ページ 26
ISSN 1340-7414
言語 日本語
著作権者 © 2010 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
NAID 120002753318
JaLCDOI 10.18926/ESR/42459
タイトル(別表記) DGEM: Digital Geological Elevation Model
フルテキストURL esr_017_021_023.pdf
著者 山川 純次| 海老 貴宏| 松本 宏文|
抄録 DGEM, a Digital Geological Elevation Model, was developed using the digital geological map and the JPGIS DEM data with some GIS application and the R-Language. In the model, the information of the geological map was combined with the DEM by their coordinates. The integration of those two digital map was performed by the R-Language, so the model can be used by some useful presentation library of the language, such as the RGL, or by some geographical calculation libraries. Moreover, the DGEM will be used by the spatial statistical libraries of the R-Language to investigate some geological spatial distributed specifications.
キーワード Digital geological map DEM JPGIS QuantumGIS R-Language
出版物タイトル Okayama University Earth Science Report
発行日 2010-12-24
17巻
1号
開始ページ 21
終了ページ 23
ISSN 1340-7414
言語 日本語
著作権者 © 2010 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
NAID 120002753317
JaLCDOI 10.18926/ESR/42458
タイトル(別表記) Comparison of large-scale cloud distribution and atmospheric fields around the Akisame (autumn rainfall) front in East Asia among 1993, 1994 and 1995
フルテキストURL esr_017_007_019.pdf
著者 福田 維子| 加藤 内藏進|
抄録 In order to examine year-to-year variability of the Akisame (autumn rainfall) frontal zone in East Asia, large-scale cloud distribution and atmospheric fields around the frontal zone were compared among 1993, 1994 and 1995, when their characteristics were rather different among each other. While the Akisame frontal zone extended zonally and the deep convective clouds tended to appear in that frontal zone near the southern coast of the Japan Islands in 1993, the frontal zone extends from southwest to northeast and the large amount of precipitation was brought mainly in the northern Japan. In 1995, although the surface front on the weather maps appeared frequently also around the southern coast of the Japan Islands, the rainfall amount there was not so large. The area with frequent appearance of the deep convective clouds in the Akisame frontal zone was seen only to the east of the Japan Islands. As such, it is noted that the active area of the Akisame frontal zone shows rather large year-to-year variability also in the zonal direction. It is also suggested that such great variability of the Akisame frontal zone in the zonal direction seems to correspond to the variations of the subtropical high and the ITCZ in the western Pacific region around September.
キーワード Akisame (autumn rainfall) front STFZ in early autumn year-to-year difference of Akisame front
出版物タイトル Okayama University Earth Science Report
発行日 2010-12-24
17巻
1号
開始ページ 7
終了ページ 19
ISSN 1340-7414
言語 日本語
著作権者 © 2010 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
NAID 120002753316
JaLCDOI 10.18926/ESR/42457
タイトル(別表記) 西南日本の熱変成超苦鉄質岩体中のかんらん石と輝石の組成変化に関する覚書
フルテキストURL esr_017_001_005.pdf
著者 野坂 俊夫|
抄録 This short article presents some diagrams showing the compositional variations of primary and metamorphic olivine, orthopyroxene and clinopyroxene in peridotites and serpentinites from thermally metamorphosed ultramafic complexes in SW Japan. In contrast to olivine, which shows a gradual change of chemical composition corresponding with metamorphic grade, orthopyroxene and clinopyroxene show clear differences in composition between primary and metamorphic phases. Compared with primary pyroxenes, even though their compositions could be variable depending on original rock composition, metamorphic orthopyroxene and metamorphic clinopyroxene is clearly deficient in Cr(2)O(3) and CaO, and in Cr(2)O(3) and Al(2)O(3), respectively. These characteristics are useful for the discrimination between the pyroxenes of different origin.
キーワード chemical composition olivine orthopyroxene clinopyroxene metaperidotite
出版物タイトル Okayama University Earth Science Report
発行日 2010-12-24
17巻
1号
開始ページ 1
終了ページ 5
ISSN 1340-7414
言語 英語
著作権者 © 2010 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
NAID 120002753315
JaLCDOI 10.18926/OER/42376
タイトル(別表記) A Study on the Methodology of the Science of Finance
フルテキストURL oer_003_1_062_087.pdf
著者 坂本 忠次|
出版物タイトル 岡山大学経済学会雑誌
発行日 1971-06-30
3巻
1号
開始ページ 62
終了ページ 87
ISSN 0386-3069
言語 日本語
論文のバージョン publisher
NAID 120002737717