検索結果 - 岡山大学学術成果リポジトリ

Investigating the Effect of Substituting a Single Cysteine Residue on the Thermal Stability of an Engineered Sweet Protein, Single-Chain Monellin

フルテキストURL	fulltext20231017-01.pdf
著者	Ohnuma, Kyosuke\| Yamashita, Atsuko\| Yasui, Norihisa\|
キーワード	Crystallography Monellin Protein Stability Recombinant Proteins
備考	The version of record of this article, first published in The Protein Journal, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10930-023-10154-0\|
発行日	2023-09-22
出版物タイトル	The Protein Journal
巻	42巻
号	6号
出版者	Springer Science and Business Media LLC
開始ページ	698
終了ページ	708
ISSN	1572-3887
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37737932
DOI	10.1007/s10930-023-10154-0
Web of Science KeyUT	001068486400001
関連URL	isVersionOf https://doi.org/10.1007/s10930-023-10154-0

Association of one-point glucocorticoid-free status with chronic damage and disease duration in systemic lupus erythematosus: a cross-sectional study

フルテキストURL	fulltext.pdf
著者	Sada, Ken-ei\| Katayama, Yu\| Asano, Yosuke\| Hayashi, Keigo\| Miyawaki, Yoshia\| Ohashi, Keiji\| Katsuyama, Eri\| Katsuyama, Takayuki\| Takano-Narazaki, Mariko\| Matsumoto, Yoshinori\| Yoshimi, Ryusuke\| Shimojima, Yasuhiro\| Ohno, Shigeru\| Kajiyama, Hiroshi\| Ichinose, Kunihiro\| Sato, Shuzo\| Fujiwara, Michio\| Yajima, Nobuyuki\|
キーワード	systemic lupus erythematosus glucocorticoids outcome assessment health care epidemiology
発行日	2022-09-27
出版物タイトル	Lupus Science & Medicine
巻	9巻
号	1号
出版者	BMJ
開始ページ	e000772
ISSN	2053-8790
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Author(s) (or their employer(s)) 2022.
論文のバージョン	publisher
PubMed ID	36167483
DOI	10.1136/lupus-2022-000772
Web of Science KeyUT	000861425300002
関連URL	isVersionOf https://doi.org/10.1136/lupus-2022-000772

Flame retardance-donated lignocellulose nanofibers (LCNFs) by the Mannich reaction with (amino-1,3,5-triazinyl)phosphoramidates and their properties

フルテキストURL	fulltext.pdf
著者	Ono, Fumiaki\| Okihara, Takumi\| Osaka, Noboru\| Nagaoka, Noriyuki\| Kameoka, Yuji\| Ishikawa, Akira\| Ooki, Hironari\| Ito, Takumi\| Todome, Daisuke\| Uemoto, Shinya\| Furutani, Mitsuaki\| Inokuchi, Tsutomu\| Okada, Kenji\|
発行日	2022-01-26
出版物タイトル	RSC Advances
巻	12巻
号	6号
出版者	Royal Society of Chemistry (RSC)
開始ページ	3300
終了ページ	3308
ISSN	2046-2069
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 The Author(s).
論文のバージョン	publisher
PubMed ID	35425348
DOI	10.1039/d1ra08716a
Web of Science KeyUT	000746872200001
関連URL	isVersionOf https://doi.org/10.1039/d1ra08716a

The number of circulating CD34-positive cells is an independent predictor of coronary artery calcification progression: Sub-analysis of a prospective multicenter study

フルテキストURL	fulltext.pdf
著者	Ichikawa, Keishi\| Miyoshi, Toru\| Osawa, Kazuhiro\| Miki, Takashi\| Kohno, Kunihisa\| Nakamura, Kazufumi\| Koyama, Yasushi\| Ito, Hiroshi\|
キーワード	coronary artery calcification computed tomography endothelial progenitor cells hypercholesterolemia
発行日	2021-11-15
出版物タイトル	Cardiology Journal
巻	29巻
号	3号
出版者	VM Media SP. zo.o VM Group SK
開始ページ	423
終了ページ	431
ISSN	1898-018X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 Via Medica
論文のバージョン	publisher
PubMed ID	34787888
DOI	10.5603/cj.a2021.0151
Web of Science KeyUT	000807916700001
関連URL	isVersionOf https://doi.org/10.5603/CJ.a2021.0151

Up-to-date evidence on image-guided thermal ablation for metastatic lung tumors: a review

フルテキストURL	fulltext.pdf
著者	Matsui, Yusuke\| Tomita, Koji\| Uka, Mayu\| Umakoshi, Noriyuki\| Kawabata, Takahiro\| Munetomo, Kazuaki\| Nagata, Shoma\| Iguchi, Toshihiro\| Hiraki, Takao\|
キーワード	Ablation Lung Pulmonary Metastasis
備考	The version of record of this article, first published in Japanese Journal of Radiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11604-022-01302-0\|
発行日	2022-07-02
出版物タイトル	Japanese Journal of Radiology
巻	40巻
号	10号
出版者	Springer Science and Business Media LLC
開始ページ	1024
終了ページ	1034
ISSN	1867-1071
NCID	AA12375935
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022
論文のバージョン	publisher
PubMed ID	35778630
DOI	10.1007/s11604-022-01302-0
Web of Science KeyUT	000819687400001
関連URL	isVersionOf https://doi.org/10.1007/s11604-022-01302-0

Detailed Anatomy of Bridging Veins Around the Foramen Magnum: a Multicenter Study Using Three-dimensional Angiography

フルテキストURL	fulltext20230912-02.pdf
著者	Hiramatsu, Masafumi\| Ozaki, Tomohiko\| Tanoue, Shuichi\| Mizutani, Katsuhiro\| Nakamura, Hajime\| Tokuyama, Kohei\| Sakata, Hiroyuki\| Matsumaru, Yuji\| Nakahara, Ichiro\| Niimi, Yasunari\| Fujinaka, Toshiyuki\| Kiyosue, Hiro\|
キーワード	Bridging vein Foramen magnum Cone-beam CT Venous phase three-dimensional rotational angiography Slab maximum intensity projection Dural arteriovenous fistula
備考	The version of record of this article, first published in Clinical Neuroradiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00062-023-01327-6\|
発行日	2023-08-08
出版物タイトル	Clinical Neuroradiology
巻	34巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	67
終了ページ	74
ISSN	1869-1439
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37552244
DOI	10.1007/s00062-023-01327-6
Web of Science KeyUT	001044319100001
関連URL	isVersionOf https://doi.org/10.1007/s00062-023-01327-6

Prognostic risk factors for postoperative long-term outcomes in elderly stage IA gastric cancer patients

フルテキストURL	fulltext.pdf
著者	Kakiuchi, Yoshihiko\| Kuroda, Shinji\| Kikuchi, Satoru\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	Gastric cancer (GC) elderly stage IA comorbidity Charlson comorbidity index (CCI)
発行日	2022-10
出版物タイトル	Journal of Gastrointestinal Oncology
巻	13巻
号	5号
出版者	AME Publishing Company
開始ページ	2178
終了ページ	2185
ISSN	2078-6891
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Journal of Gastrointestinal Oncology.
論文のバージョン	publisher
PubMed ID	36388703
DOI	10.21037/jgo-22-527
Web of Science KeyUT	000864732300001
関連URL	isVersionOf https://doi.org/10.21037/jgo-22-527

Effects of the rigid and sterically bulky structure of non-fused nonfullerene acceptors on transient photon-to-current dynamics

フルテキストURL	fulltext.pdf
著者	Jinnai, Seihou\| Murayama, Kasumi\| Nagai, Keisuke\| Mineshita, Megumi\| Kato, Kosaku\| Muraoka, Azusa\| Yamakata, Akira\| Saeki, Akinori\| Kobori, Yasuhiro\| Ie, Yutaka\|
発行日	2022-08-09
出版物タイトル	Journal of Materials Chemistry A
巻	10巻
号	37号
出版者	Royal Society of Chemistry (RSC)
開始ページ	20035
終了ページ	20047
ISSN	2050-7488
NCID	AA12603290
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Royal Society of Chemistry 2022
論文のバージョン	publisher
DOI	10.1039/d2ta02604j
Web of Science KeyUT	000837730900001
関連URL	isVersionOf https://doi.org/10.1039/d2ta02604j

Data-driven evolutionary computation for service constrained inventory optimization in multi-echelon supply chains

フルテキストURL	fulltext.pdf
著者	Liu, Ziang\| Nishi, Tatsushi\|
キーワード	Evolutionary algorithm Inventory management Data-driven Supply chain Digital twin
備考	The version of record of this article, first published in Complex & Intelligent Systems, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40747-023-01179-0\|
発行日	2023-08-09
出版物タイトル	Complex & Intelligent Systems
巻	10巻
号	1号
出版者	Springer
開始ページ	825
終了ページ	846
ISSN	2199-4536
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
DOI	10.1007/s40747-023-01179-0
Web of Science KeyUT	001044871100001
関連URL	isVersionOf https://doi.org/10.1007/s40747-023-01179-0

Relationship between the Arthroscopic Findings and Pathology of Greater Trochanteric Pain Syndrome

JaLCDOI	10.18926/AMO/65746
フルテキストURL	77_4_371.pdf
著者	Iwamoto, Yosuke\| Kaya, Mitsunori\| Kijima, Hiroaki\| Fujii, Masashi\| Nagahata, Itsuki\| Miyakoshi, Naohisa\|
抄録	In recent publications on greater trochanteric pain syndrome (GTPS), the pathology receiving the most attention has been gluteus medius muscle tendinous injury, and surgical techniques such as gluteus medius tendon repair and their outcomes for GTPS have been reported. In our department-related facilities, arthroscopic surgeries are routinely performed for the patients with recalcitrant GTPS. A total of 51 patients were diagnosed with GTPS. Surgical treatment was carried out 22 patients (24 joints; 4 males and 18 females; mean age at surgery of 52.0 years). Arthroscopic findings confirmed bursitis in all 24 joints. In all cases, debridement of the greater trochanter bursa provided rapid relief of greater trochanter pain. The Numerical Rating Scale showed significant improvement, from the preoperative mean of 7.8 (range, 6-10) to the postoperative day 7 mean of 1.6 (range, 0-3). The modified Harris Hip Score was significantly improved from the preoperative mean of 65.5 (range, 52.5-78.3) to the final follow-up (average 2.9 months) mean of 96.0 (range, 85.2-100). Fascial damage of the gluteus medius muscle was observed in 21 joints while only 2 patients had a gluteus medius tendinous injury. Greater trochanteric bursitis and fascia or muscle-fiber injury of the gluteus medius muscle are the most common pathologies in patients with lateral hip pain.
キーワード	greater trochanteric pain syndrome endoscopic findings bursitis
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-08
巻	77巻
号	4号
出版者	Okayama University Medical School
開始ページ	371
終了ページ	375
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37635137
Web of Science KeyUT	001163659800005

Important roles of odontoblast membrane phospholipids in early dentin mineralization

フルテキストURL	fulltext.pdf
著者	Anada, Risa\| Hara, Emilio Satoshi\| Nagaoka, Noriyuki\| Okada, Masahiro\| Kamioka, Hiroshi\| Matsumoto, Takuya\|
発行日	2022-12-07
出版物タイトル	Journal of Materials Chemistry B
巻	11巻
号	3号
出版者	Royal Society of Chemistry (RSC)
開始ページ	657
終了ページ	666
ISSN	2050-750X
NCID	AA12605004
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Royal Society of Chemistry 2023
論文のバージョン	publisher
PubMed ID	32254824
DOI	10.1039/d2tb02351b
Web of Science KeyUT	000449697700013
関連URL	isVersionOf https://doi.org/10.1039/D2TB02351B

Clinical evaluation of suture materials for transtibial pullout repair of medial meniscus posterior root tear

フルテキストURL	fulltext.pdf
著者	Hiranaka, Takaaki\| Furumatsu, Takayuki\| Okazaki, Yuki\| Kintaka, Keisuke\| Kamatsuki, Yusuke\| Zhang, Ximing\| Xue, Haowei\| Hamada, Masanori\| Ozaki, Toshifumi\|
キーワード	Medial meniscus Posterior root tear Clinical outcome Meniscal healing Suture material Pullout repair
備考	The version of record of this article, first published in Knee Surgery & Related Research, is available online at Publisher’s website: http://dx.doi.org/10.1186/s43019-022-00167-x\|
発行日	2022-10-08
出版物タイトル	Knee Surgery & Related Research
巻	34巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	39
ISSN	2234-2451
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	36209256
DOI	10.1186/s43019-022-00167-x
Web of Science KeyUT	000865171800001
関連URL	isVersionOf https://doi.org/10.1186/s43019-022-00167-x

Refining the evolutionary tree of the horse Y chromosome

フルテキストURL	fulltext.pdf
著者	Bozlak, Elif\| Radovic, Lara\| Remer, Viktoria\| Rigler, Doris\| Allen, Lucy\| Brem, Gottfried\| Stalder, Gabrielle\| Castaneda, Caitlin\| Cothran, Gus\| Raudsepp, Terje\| Okuda, Yu\| Moe, Kyaw Kyaw\| Moe, Hla Hla\| Kounnavongsa, Bounthavone\| Keonouchanh, Soukanh\| Van, Nguyen Huu\| Vu, Van Hai\| Shah, Manoj Kumar\| Nishibori, Masahide\| Kazymbet, Polat\| Bakhtin, Meirat\| Zhunushov, Asankadyr\| Paul, Ripon Chandra\| Dashnyam, Bumbein\| Nozawa, Ken\| Almarzook, Saria\| Brockmann, Gudrun A.\| Reissmann, Monika\| Antczak, Douglas F.\| Miller, Donald C.\| Sadeghi, Raheleh\| Butler-Wemken, Ines von\| Kostaras, Nikos\| Han, Haige\| Manglai, Dugarjaviin\| Abdurasulov, Abdugani\| Sukhbaatar, Boldbaatar\| Ropka-Molik, Katarzyna\| Stefaniuk-Szmukier, Monika\| Lopes, Maria Susana\| Machado, Artur da Câmara\| Kalashnikov, Valery V.\| Kalinkova, Liliya\| Zaitev, Alexander M.\| Novoa-Bravo, Miguel\| Lindgren, Gabriella\| Brooks, Samantha\| Rosa, Laura Patterson\| Orlando, Ludovic\| Juras, Rytis\| Kunieda, Tetsuo\| Wallner, Barbara\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-35539-0\|
発行日	2023-06-02
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	8954
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37268661
DOI	10.1038/s41598-023-35539-0
Web of Science KeyUT	001000613900036
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-35539-0

Epidemiological features of acute medial meniscus posterior root tears

フルテキストURL	fulltext20230703-01.pdf
著者	Kamatsuki, Yusuke\| Furumatsu, Takayuki\| Hiranaka, Takaaki\| Okazaki, Yuki\| Kintaka, Keisuke\| Kodama, Yuya\| Miyazawa, Shinichi\| Ozaki, Toshifumi\|
キーワード	Body mass index Medial meniscus Painful popping Posterior root tear Pullout repair
備考	The version of record of this article, first published in International Orthopaedics, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00264-023-05848-0\|
発行日	2023-06-17
出版物タイトル	International Orthopaedics
巻	47巻
号	10号
出版者	Springer Science and Business Media LLC
開始ページ	2537
終了ページ	2545
ISSN	0341-2695
NCID	AA0068148X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37329453
DOI	10.1007/s00264-023-05848-0
Web of Science KeyUT	001007187100001
関連URL	isVersionOf https://doi.org/10.1007/s00264-023-05848-0

The chemokine monocyte chemoattractant protein-1/CCL2 is a promoter of breast cancer metastasis

フルテキストURL	fulltext20230621-01.pdf
著者	Yoshimura, Teizo\| Li, Chunning\| Wang, Yuze\| Matsukawa, Akihiro\|
キーワード	Breast cancer chemokines chemokine receptors metastasis macrophages
備考	The version of record of this article, first published in Cellular & Molecular Immunology, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41423-023-01013-0\|
発行日	2023-05-19
出版物タイトル	Cellular & Molecular Immunology
巻	20巻
号	7号
出版者	Springer Science and Business Media LLC
開始ページ	714
終了ページ	738
ISSN	2042-0226
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	37208442
DOI	10.1038/s41423-023-01013-0
Web of Science KeyUT	000990897000001
関連URL	isVersionOf https://doi.org/10.1038/s41423-023-01013-0

A Comparison of the Efficacy of Plastic Stent Placement Above and Across the Sphincter of Oddi for Benign Biliary Hilar Stricture

JaLCDOI	10.18926/AMO/65494
フルテキストURL	77_3_291.pdf
著者	Himei, Hitomi\| Kato, Hironari\| Saragai, Yosuke\| Fujii, Yuki\| Yamazaki, Tatsuhiro\| Uchida, Daisuke\| Matsumoto, Kazuyuki\| Horiguchi, Shigeru\| Tsutsumi, Koichiro\| Okada, Hiroyuki\|
抄録	We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal.
キーワード	benign biliary stricture inside stent plastic stent
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-06
巻	77巻
号	3号
出版者	Okayama University Medical School
開始ページ	291
終了ページ	299
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37357630
Web of Science KeyUT	001026279600007

Usefulness of Simple Diffusion Kurtosis Imaging for Head and Neck Tumors: An Early Clinical Study

JaLCDOI	10.18926/AMO/65492
フルテキストURL	77_3_273.pdf
著者	Shimizu, Yudai\| Kuroda, Masahiro\| Nakamitsu, Yuki\| Al-Hammad, Wlla E.\| Yoshida, Suzuka\| Fukumura, Yuka\| Nakamura, Yoshihide\| Kuroda, Kazuhiro\| Kamizaki, Ryo\| Imajoh, Satoshi\| Tanabe, Yoshinori\| Sugimoto, Kohei\| Oita, Masataka\| Sugianto, Irfan\| Bamgbose, Babatunde O.\| Yanagi, Yoshinobu\| Asaumi, Junichi\|
抄録	Diffusion kurtosis (DK) imaging (DKI), a type of restricted diffusion-weighted imaging, has been reported to be useful for tumor diagnoses in clinical studies. We developed a software program to simultaneously create DK images with apparent diffusion coefficient (ADC) maps and conducted an initial clinical study. Multi-shot echo-planar diffusion-weighted images were obtained at b-values of 0, 400, and 800 sec/mm2 for simple DKI, and DK images were created simultaneously with the ADC map. The usefulness of the DK image and ADC map was evaluated using a pixel analysis of all pixels and a median analysis of the pixels of each case. Tumor and normal tissues differed significantly in both pixel and median analyses. In the pixel analysis, the area under the curve was 0.64 for the mean kurtosis (MK) value and 0.77 for the ADC value. In the median analysis, the MK value was 0.74, and the ADC value was 0.75. The MK and ADC values correlated moderately in the pixel analysis and strongly in the median analysis. Our simple DKI system created DK images simultaneously with ADC maps, and the obtained MK and ADC values were useful for differentiating head and neck tumors from normal tissue.
キーワード	simple diffusion kurtosis imaging mean kurtosis clinical trial head and neck tumor magnetic resonance imaging
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-06
巻	77巻
号	3号
出版者	Okayama University Medical School
開始ページ	273
終了ページ	280
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37357628
Web of Science KeyUT	001026279600005

Early Fluid Balance Is Associated with 90-Day Mortality in Patients Receiving Continuous Renal Replacement Therapy

JaLCDOI	10.18926/AMO/65491
フルテキストURL	77_3_263.pdf
著者	Guo, Yusheng\| Kosaka, Junko\| Morimatsu, Hiroshi\|
抄録	Continuous renal replacement therapy (CRRT) is widely used to control fluid balance, but the optimal fluid balance to improve the prognosis of patients remains debated. Appropriate fluid management may depend on hemodynamic status. We investigated the association between 90-day mortality and fluid balance/mean arterial pressure (MAP) in patients receiving CRRT. This single-center retrospective study was conducted between May 2018 and March 2021. Based on the cumulative fluid balance at 72 h after initiation of CRRT, the cases were divided into negative (< 0 mL) and positive (> 0 mL) fluid balance groups. Ninety-day mortality was higher in the positive fluid balance group (p=0.009). At 4 h before and after CRRT initiation, the mean MAP was lower in the positive fluid balance group (p<0.05). After multivariate cox adjustment, 72-h positive fluid balance was independently associated with 90-day mortality (p=0.004). In addition, the cumulative fluid balance was associated with 90-day mortality (p<0.05) in cases without shock, high APACHE II score, sepsis, dialysis dependence, or vasopressor use. A 72-h positive fluid balance was associated with 90-day mortality in patients receiving CRRT.
キーワード	fluid management continuous renal replacement therapy mortality mean arterial pressure daily cumulative fluid balance
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-06
巻	77巻
号	3号
出版者	Okayama University Medical School
開始ページ	263
終了ページ	272
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37357627
Web of Science KeyUT	001026279600004

Endocrinological Changes after Anamorelin Administration in Patients with Gastrointestinal Cancer

JaLCDOI	10.18926/AMO/65488
フルテキストURL	77_3_235.pdf
著者	Kuraoka, Sakiko\| Iwamuro, Masaya\| Satomi, Takuya\| Yamazaki, Tatsuhiro\| Hamada, Kenta\| Kono, Yoshiyasu\| Kanzaki, Hiromitsu\| Kato, Hironari\| Otsuka, Fumio\| Okada, Hiroyuki\|
抄録	Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users.
キーワード	anamorelin body weight cancer cachexia endocrine system
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2023-06
巻	77巻
号	3号
出版者	Okayama University Medical School
開始ページ	235
終了ページ	241
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	37357624
Web of Science KeyUT	001026279600001

RNA editing facilitates the enhanced production of neoantigens during the simultaneous administration of oxaliplatin and radiotherapy in colorectal cancer

フルテキストURL	K0006782_abstract_review.pdf K0006782_fulltext.pdf K0006782_other_figure.pdf K0006782_other_suppl.pdf K0006782_summary.pdf
著者	小松泰浩\|
発行日	2023-03-24
資料タイプ	学位論文
学位授与番号	甲第6782号
学位授与年月日	2023-03-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© The Author(s) 2022