result 982 件
| FullText URL | fulltext20231017-01.pdf |
|---|---|
| Author | Ohnuma, Kyosuke| Yamashita, Atsuko| Yasui, Norihisa| |
| Keywords | Crystallography Monellin Protein Stability Recombinant Proteins |
| Note | The version of record of this article, first published in The Protein Journal, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10930-023-10154-0| |
| Published Date | 2023-09-22 |
| Publication Title | The Protein Journal |
| Volume | volume42 |
| Issue | issue6 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 698 |
| End Page | 708 |
| ISSN | 1572-3887 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37737932 |
| DOI | 10.1007/s10930-023-10154-0 |
| Web of Science KeyUT | 001068486400001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10930-023-10154-0 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sada, Ken-ei| Katayama, Yu| Asano, Yosuke| Hayashi, Keigo| Miyawaki, Yoshia| Ohashi, Keiji| Katsuyama, Eri| Katsuyama, Takayuki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Yoshimi, Ryusuke| Shimojima, Yasuhiro| Ohno, Shigeru| Kajiyama, Hiroshi| Ichinose, Kunihiro| Sato, Shuzo| Fujiwara, Michio| Yajima, Nobuyuki| |
| Keywords | systemic lupus erythematosus glucocorticoids outcome assessment health care epidemiology |
| Published Date | 2022-09-27 |
| Publication Title | Lupus Science & Medicine |
| Volume | volume9 |
| Issue | issue1 |
| Publisher | BMJ |
| Start Page | e000772 |
| ISSN | 2053-8790 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Author(s) (or their employer(s)) 2022. |
| File Version | publisher |
| PubMed ID | 36167483 |
| DOI | 10.1136/lupus-2022-000772 |
| Web of Science KeyUT | 000861425300002 |
| Related Url | isVersionOf https://doi.org/10.1136/lupus-2022-000772 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ono, Fumiaki| Okihara, Takumi| Osaka, Noboru| Nagaoka, Noriyuki| Kameoka, Yuji| Ishikawa, Akira| Ooki, Hironari| Ito, Takumi| Todome, Daisuke| Uemoto, Shinya| Furutani, Mitsuaki| Inokuchi, Tsutomu| Okada, Kenji| |
| Published Date | 2022-01-26 |
| Publication Title | RSC Advances |
| Volume | volume12 |
| Issue | issue6 |
| Publisher | Royal Society of Chemistry (RSC) |
| Start Page | 3300 |
| End Page | 3308 |
| ISSN | 2046-2069 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s). |
| File Version | publisher |
| PubMed ID | 35425348 |
| DOI | 10.1039/d1ra08716a |
| Web of Science KeyUT | 000746872200001 |
| Related Url | isVersionOf https://doi.org/10.1039/d1ra08716a |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ichikawa, Keishi| Miyoshi, Toru| Osawa, Kazuhiro| Miki, Takashi| Kohno, Kunihisa| Nakamura, Kazufumi| Koyama, Yasushi| Ito, Hiroshi| |
| Keywords | coronary artery calcification computed tomography endothelial progenitor cells hypercholesterolemia |
| Published Date | 2021-11-15 |
| Publication Title | Cardiology Journal |
| Volume | volume29 |
| Issue | issue3 |
| Publisher | VM Media SP. zo.o VM Group SK |
| Start Page | 423 |
| End Page | 431 |
| ISSN | 1898-018X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Via Medica |
| File Version | publisher |
| PubMed ID | 34787888 |
| DOI | 10.5603/cj.a2021.0151 |
| Web of Science KeyUT | 000807916700001 |
| Related Url | isVersionOf https://doi.org/10.5603/CJ.a2021.0151 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsui, Yusuke| Tomita, Koji| Uka, Mayu| Umakoshi, Noriyuki| Kawabata, Takahiro| Munetomo, Kazuaki| Nagata, Shoma| Iguchi, Toshihiro| Hiraki, Takao| |
| Keywords | Ablation Lung Pulmonary Metastasis |
| Note | The version of record of this article, first published in Japanese Journal of Radiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11604-022-01302-0| |
| Published Date | 2022-07-02 |
| Publication Title | Japanese Journal of Radiology |
| Volume | volume40 |
| Issue | issue10 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1024 |
| End Page | 1034 |
| ISSN | 1867-1071 |
| NCID | AA12375935 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 35778630 |
| DOI | 10.1007/s11604-022-01302-0 |
| Web of Science KeyUT | 000819687400001 |
| Related Url | isVersionOf https://doi.org/10.1007/s11604-022-01302-0 |
| FullText URL | fulltext20230912-02.pdf |
|---|---|
| Author | Hiramatsu, Masafumi| Ozaki, Tomohiko| Tanoue, Shuichi| Mizutani, Katsuhiro| Nakamura, Hajime| Tokuyama, Kohei| Sakata, Hiroyuki| Matsumaru, Yuji| Nakahara, Ichiro| Niimi, Yasunari| Fujinaka, Toshiyuki| Kiyosue, Hiro| |
| Keywords | Bridging vein Foramen magnum Cone-beam CT Venous phase three-dimensional rotational angiography Slab maximum intensity projection Dural arteriovenous fistula |
| Note | The version of record of this article, first published in Clinical Neuroradiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00062-023-01327-6| |
| Published Date | 2023-08-08 |
| Publication Title | Clinical Neuroradiology |
| Volume | volume34 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 67 |
| End Page | 74 |
| ISSN | 1869-1439 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37552244 |
| DOI | 10.1007/s00062-023-01327-6 |
| Web of Science KeyUT | 001044319100001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00062-023-01327-6 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kakiuchi, Yoshihiko| Kuroda, Shinji| Kikuchi, Satoru| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Keywords | Gastric cancer (GC) elderly stage IA comorbidity Charlson comorbidity index (CCI) |
| Published Date | 2022-10 |
| Publication Title | Journal of Gastrointestinal Oncology |
| Volume | volume13 |
| Issue | issue5 |
| Publisher | AME Publishing Company |
| Start Page | 2178 |
| End Page | 2185 |
| ISSN | 2078-6891 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Journal of Gastrointestinal Oncology. |
| File Version | publisher |
| PubMed ID | 36388703 |
| DOI | 10.21037/jgo-22-527 |
| Web of Science KeyUT | 000864732300001 |
| Related Url | isVersionOf https://doi.org/10.21037/jgo-22-527 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Jinnai, Seihou| Murayama, Kasumi| Nagai, Keisuke| Mineshita, Megumi| Kato, Kosaku| Muraoka, Azusa| Yamakata, Akira| Saeki, Akinori| Kobori, Yasuhiro| Ie, Yutaka| |
| Published Date | 2022-08-09 |
| Publication Title | Journal of Materials Chemistry A |
| Volume | volume10 |
| Issue | issue37 |
| Publisher | Royal Society of Chemistry (RSC) |
| Start Page | 20035 |
| End Page | 20047 |
| ISSN | 2050-7488 |
| NCID | AA12603290 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Royal Society of Chemistry 2022 |
| File Version | publisher |
| DOI | 10.1039/d2ta02604j |
| Web of Science KeyUT | 000837730900001 |
| Related Url | isVersionOf https://doi.org/10.1039/d2ta02604j |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Liu, Ziang| Nishi, Tatsushi| |
| Keywords | Evolutionary algorithm Inventory management Data-driven Supply chain Digital twin |
| Note | The version of record of this article, first published in Complex & Intelligent Systems, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40747-023-01179-0| |
| Published Date | 2023-08-09 |
| Publication Title | Complex & Intelligent Systems |
| Volume | volume10 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 825 |
| End Page | 846 |
| ISSN | 2199-4536 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| DOI | 10.1007/s40747-023-01179-0 |
| Web of Science KeyUT | 001044871100001 |
| Related Url | isVersionOf https://doi.org/10.1007/s40747-023-01179-0 |
| JaLCDOI | 10.18926/AMO/65746 |
|---|---|
| FullText URL | 77_4_371.pdf |
| Author | Iwamoto, Yosuke| Kaya, Mitsunori| Kijima, Hiroaki| Fujii, Masashi| Nagahata, Itsuki| Miyakoshi, Naohisa| |
| Abstract | In recent publications on greater trochanteric pain syndrome (GTPS), the pathology receiving the most attention has been gluteus medius muscle tendinous injury, and surgical techniques such as gluteus medius tendon repair and their outcomes for GTPS have been reported. In our department-related facilities, arthroscopic surgeries are routinely performed for the patients with recalcitrant GTPS. A total of 51 patients were diagnosed with GTPS. Surgical treatment was carried out 22 patients (24 joints; 4 males and 18 females; mean age at surgery of 52.0 years). Arthroscopic findings confirmed bursitis in all 24 joints. In all cases, debridement of the greater trochanter bursa provided rapid relief of greater trochanter pain. The Numerical Rating Scale showed significant improvement, from the preoperative mean of 7.8 (range, 6-10) to the postoperative day 7 mean of 1.6 (range, 0-3). The modified Harris Hip Score was significantly improved from the preoperative mean of 65.5 (range, 52.5-78.3) to the final follow-up (average 2.9 months) mean of 96.0 (range, 85.2-100). Fascial damage of the gluteus medius muscle was observed in 21 joints while only 2 patients had a gluteus medius tendinous injury. Greater trochanteric bursitis and fascia or muscle-fiber injury of the gluteus medius muscle are the most common pathologies in patients with lateral hip pain. |
| Keywords | greater trochanteric pain syndrome endoscopic findings bursitis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 371 |
| End Page | 375 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635137 |
| Web of Science KeyUT | 001163659800005 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Anada, Risa| Hara, Emilio Satoshi| Nagaoka, Noriyuki| Okada, Masahiro| Kamioka, Hiroshi| Matsumoto, Takuya| |
| Published Date | 2022-12-07 |
| Publication Title | Journal of Materials Chemistry B |
| Volume | volume11 |
| Issue | issue3 |
| Publisher | Royal Society of Chemistry (RSC) |
| Start Page | 657 |
| End Page | 666 |
| ISSN | 2050-750X |
| NCID | AA12605004 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Royal Society of Chemistry 2023 |
| File Version | publisher |
| PubMed ID | 32254824 |
| DOI | 10.1039/d2tb02351b |
| Web of Science KeyUT | 000449697700013 |
| Related Url | isVersionOf https://doi.org/10.1039/D2TB02351B |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hiranaka, Takaaki| Furumatsu, Takayuki| Okazaki, Yuki| Kintaka, Keisuke| Kamatsuki, Yusuke| Zhang, Ximing| Xue, Haowei| Hamada, Masanori| Ozaki, Toshifumi| |
| Keywords | Medial meniscus Posterior root tear Clinical outcome Meniscal healing Suture material Pullout repair |
| Note | The version of record of this article, first published in Knee Surgery & Related Research, is available online at Publisher’s website: http://dx.doi.org/10.1186/s43019-022-00167-x| |
| Published Date | 2022-10-08 |
| Publication Title | Knee Surgery & Related Research |
| Volume | volume34 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 39 |
| ISSN | 2234-2451 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. |
| File Version | publisher |
| PubMed ID | 36209256 |
| DOI | 10.1186/s43019-022-00167-x |
| Web of Science KeyUT | 000865171800001 |
| Related Url | isVersionOf https://doi.org/10.1186/s43019-022-00167-x |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Bozlak, Elif| Radovic, Lara| Remer, Viktoria| Rigler, Doris| Allen, Lucy| Brem, Gottfried| Stalder, Gabrielle| Castaneda, Caitlin| Cothran, Gus| Raudsepp, Terje| Okuda, Yu| Moe, Kyaw Kyaw| Moe, Hla Hla| Kounnavongsa, Bounthavone| Keonouchanh, Soukanh| Van, Nguyen Huu| Vu, Van Hai| Shah, Manoj Kumar| Nishibori, Masahide| Kazymbet, Polat| Bakhtin, Meirat| Zhunushov, Asankadyr| Paul, Ripon Chandra| Dashnyam, Bumbein| Nozawa, Ken| Almarzook, Saria| Brockmann, Gudrun A.| Reissmann, Monika| Antczak, Douglas F.| Miller, Donald C.| Sadeghi, Raheleh| Butler-Wemken, Ines von| Kostaras, Nikos| Han, Haige| Manglai, Dugarjaviin| Abdurasulov, Abdugani| Sukhbaatar, Boldbaatar| Ropka-Molik, Katarzyna| Stefaniuk-Szmukier, Monika| Lopes, Maria Susana| Machado, Artur da Câmara| Kalashnikov, Valery V.| Kalinkova, Liliya| Zaitev, Alexander M.| Novoa-Bravo, Miguel| Lindgren, Gabriella| Brooks, Samantha| Rosa, Laura Patterson| Orlando, Ludovic| Juras, Rytis| Kunieda, Tetsuo| Wallner, Barbara| |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-35539-0| |
| Published Date | 2023-06-02 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 8954 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37268661 |
| DOI | 10.1038/s41598-023-35539-0 |
| Web of Science KeyUT | 001000613900036 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-023-35539-0 |
| FullText URL | fulltext20230703-01.pdf |
|---|---|
| Author | Kamatsuki, Yusuke| Furumatsu, Takayuki| Hiranaka, Takaaki| Okazaki, Yuki| Kintaka, Keisuke| Kodama, Yuya| Miyazawa, Shinichi| Ozaki, Toshifumi| |
| Keywords | Body mass index Medial meniscus Painful popping Posterior root tear Pullout repair |
| Note | The version of record of this article, first published in International Orthopaedics, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00264-023-05848-0| |
| Published Date | 2023-06-17 |
| Publication Title | International Orthopaedics |
| Volume | volume47 |
| Issue | issue10 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 2537 |
| End Page | 2545 |
| ISSN | 0341-2695 |
| NCID | AA0068148X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37329453 |
| DOI | 10.1007/s00264-023-05848-0 |
| Web of Science KeyUT | 001007187100001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00264-023-05848-0 |
| FullText URL | fulltext20230621-01.pdf |
|---|---|
| Author | Yoshimura, Teizo| Li, Chunning| Wang, Yuze| Matsukawa, Akihiro| |
| Keywords | Breast cancer chemokines chemokine receptors metastasis macrophages |
| Note | The version of record of this article, first published in Cellular & Molecular Immunology, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41423-023-01013-0| |
| Published Date | 2023-05-19 |
| Publication Title | Cellular & Molecular Immunology |
| Volume | volume20 |
| Issue | issue7 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 714 |
| End Page | 738 |
| ISSN | 2042-0226 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37208442 |
| DOI | 10.1038/s41423-023-01013-0 |
| Web of Science KeyUT | 000990897000001 |
| Related Url | isVersionOf https://doi.org/10.1038/s41423-023-01013-0 |
| JaLCDOI | 10.18926/AMO/65494 |
|---|---|
| FullText URL | 77_3_291.pdf |
| Author | Himei, Hitomi| Kato, Hironari| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Abstract | We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal. |
| Keywords | benign biliary stricture inside stent plastic stent |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357630 |
| Web of Science KeyUT | 001026279600007 |
| JaLCDOI | 10.18926/AMO/65492 |
|---|---|
| FullText URL | 77_3_273.pdf |
| Author | Shimizu, Yudai| Kuroda, Masahiro| Nakamitsu, Yuki| Al-Hammad, Wlla E.| Yoshida, Suzuka| Fukumura, Yuka| Nakamura, Yoshihide| Kuroda, Kazuhiro| Kamizaki, Ryo| Imajoh, Satoshi| Tanabe, Yoshinori| Sugimoto, Kohei| Oita, Masataka| Sugianto, Irfan| Bamgbose, Babatunde O.| Yanagi, Yoshinobu| Asaumi, Junichi| |
| Abstract | Diffusion kurtosis (DK) imaging (DKI), a type of restricted diffusion-weighted imaging, has been reported to be useful for tumor diagnoses in clinical studies. We developed a software program to simultaneously create DK images with apparent diffusion coefficient (ADC) maps and conducted an initial clinical study. Multi-shot echo-planar diffusion-weighted images were obtained at b-values of 0, 400, and 800 sec/mm2 for simple DKI, and DK images were created simultaneously with the ADC map. The usefulness of the DK image and ADC map was evaluated using a pixel analysis of all pixels and a median analysis of the pixels of each case. Tumor and normal tissues differed significantly in both pixel and median analyses. In the pixel analysis, the area under the curve was 0.64 for the mean kurtosis (MK) value and 0.77 for the ADC value. In the median analysis, the MK value was 0.74, and the ADC value was 0.75. The MK and ADC values correlated moderately in the pixel analysis and strongly in the median analysis. Our simple DKI system created DK images simultaneously with ADC maps, and the obtained MK and ADC values were useful for differentiating head and neck tumors from normal tissue. |
| Keywords | simple diffusion kurtosis imaging mean kurtosis clinical trial head and neck tumor magnetic resonance imaging |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 273 |
| End Page | 280 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357628 |
| Web of Science KeyUT | 001026279600005 |
| JaLCDOI | 10.18926/AMO/65491 |
|---|---|
| FullText URL | 77_3_263.pdf |
| Author | Guo, Yusheng| Kosaka, Junko| Morimatsu, Hiroshi| |
| Abstract | Continuous renal replacement therapy (CRRT) is widely used to control fluid balance, but the optimal fluid balance to improve the prognosis of patients remains debated. Appropriate fluid management may depend on hemodynamic status. We investigated the association between 90-day mortality and fluid balance/mean arterial pressure (MAP) in patients receiving CRRT. This single-center retrospective study was conducted between May 2018 and March 2021. Based on the cumulative fluid balance at 72 h after initiation of CRRT, the cases were divided into negative (< 0 mL) and positive (> 0 mL) fluid balance groups. Ninety-day mortality was higher in the positive fluid balance group (p=0.009). At 4 h before and after CRRT initiation, the mean MAP was lower in the positive fluid balance group (p<0.05). After multivariate cox adjustment, 72-h positive fluid balance was independently associated with 90-day mortality (p=0.004). In addition, the cumulative fluid balance was associated with 90-day mortality (p<0.05) in cases without shock, high APACHE II score, sepsis, dialysis dependence, or vasopressor use. A 72-h positive fluid balance was associated with 90-day mortality in patients receiving CRRT. |
| Keywords | fluid management continuous renal replacement therapy mortality mean arterial pressure daily cumulative fluid balance |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 263 |
| End Page | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357627 |
| Web of Science KeyUT | 001026279600004 |
| JaLCDOI | 10.18926/AMO/65488 |
|---|---|
| FullText URL | 77_3_235.pdf |
| Author | Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki| |
| Abstract | Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users. |
| Keywords | anamorelin body weight cancer cachexia endocrine system |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 235 |
| End Page | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357624 |
| Web of Science KeyUT | 001026279600001 |
| FullText URL | K0006782_abstract_review.pdf K0006782_fulltext.pdf K0006782_other_figure.pdf K0006782_other_suppl.pdf K0006782_summary.pdf |
|---|---|
| Author | KOMATSU, Yasuhiro| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6782号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © The Author(s) 2022 |
