検索結果 - 岡山大学学術成果リポジトリ

Uniform coating of magnesium oxide crystal with reduced graphene oxide achieves moisture barrier performance

フルテキストURL	fulltext20220117-1.pdf
著者	Saito, Akinori\| Obata, Seiji\| Nishina, Yuta\|
キーワード	magnesium oxide graphene oxide surface coating moisture resistance
備考	© 2021 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.apsusc.2021.151483 .\| This fulltext is available in Oct. 2023.\|
発行日	2022-01
出版物タイトル	Applied Surface Science
巻	573巻
号	30号
出版者	Elsevier BV
開始ページ	151483
ISSN	0169-4332
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Elsevier B.V
論文のバージョン	author
DOI	10.1016/j.apsusc.2021.151483
Web of Science KeyUT	000724862200001
関連URL	isVersionOf https://doi.org/10.1016/j.apsusc.2021.151483

The Small GTPase OsRac1 Forms Two Distinct Immune Receptor Complexes Containing the PRR OsCERK1 and the NLR Pit

フルテキストURL	fulltext20220106-2.pdf
著者	Akamatsu, Akira\| Fujiwara, Masayuki\| Hamada, Satoshi\| Wakabayashi, Megumi\| Yao, Ai\| Wang, Qiong\| Kosami, Ken-ichi\| Dang, Thu Thi\| Kaneko-Kawano, Takako\| Fukada, Fumi\| Shimamoto, Ko\| Kawano, Yoji\|
備考	This is a pre-copyedited, author-produced version of an article accepted for publication in [Plant and Cell Physiology] following peer review. The version of record [Akira Akamatsu, Masayuki Fujiwara, Satoshi Hamada, Megumi Wakabayashi, Ai Yao, Qiong Wang, Ken-ichi Kosami, Thu Thi Dang, Takako Kaneko-Kawano, Fumi Fukada, Ko Shimamoto, Yoji Kawano, The Small GTPase OsRac1 Forms Two Distinct Immune Receptor Complexes Containing the PRR OsCERK1 and the NLR Pit, Plant and Cell Physiology, Volume 62, Issue 11, November 2021, Pages 1662–1675, https://doi.org/10.1093/pcp/pcab121] is available online at: https://doi.org/10.1093/pcp/pcab121\|
発行日	2021-8-27
出版物タイトル	Plant and Cell Physiology
巻	62巻
号	11号
出版者	Oxford University Press (OUP)
開始ページ	1662
終了ページ	1675
ISSN	0032-0781
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved.
論文のバージョン	author
PubMed ID	34329461
DOI	10.1093/pcp/pcab121
Web of Science KeyUT	000734079300003
関連URL	isVersionOf https://doi.org/10.1093/pcp/pcab121

A repair technique using two simple stitches reduces the short-term postoperative medial meniscus extrusion after pullout repair for medial meniscus posterior root tear

フルテキストURL	fulltext20220106-3.pdf Int_Orthop_Figure P.pdf Fig2.pdf Fig3.pdf Tables20220106-3.pdf
著者	Hiranaka, Takaaki\| Furumatsu, Takayuki\| Masuda, Shin\| Okazaki, Yoshiki\| Okazaki, Yuki\| Kodama, Yuya\| Kamatsuki, Yusuke\| Kajiki, Yuya\| Zhang, Ximing\| Ozaki, Toshifumi\|
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00590-020-02647-w\| This is an Accepted Manuscript published by Springer.\|
発行日	2020-3-10
出版物タイトル	European Journal of Orthopaedic Surgery & Traumatology
巻	30巻
号	5号
出版者	Springer Science and Business Media LLC
開始ページ	901
終了ページ	908
ISSN	1633-8065
NCID	AA11622799
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Springer-Verlag France SAS, part of Springer Nature 2020
論文のバージョン	author
PubMed ID	32157399
DOI	10.1007/s00590-020-02647-w
Web of Science KeyUT	000729760300019
関連URL	isVersionOf https://doi.org/10.1007/s00590-020-02647-w

「すずろ」「そぞろ」の意味は「むやみやたらに」ではない─新訳語がすでに古語辞典の水面下で広がっている状況の報告と入試採点等への警告──附載、濱田啓介先生『雨月物語』「仏法僧」冒頭・末尾解釈説

JaLCDOI	10.18926/okadai-bun-kiyou/63066
タイトル（別表記）	We Should not Translate the Ancient Words "suzuro" and "sozoro" to "muyami" or "yatara"
フルテキストURL	jfl_074_069_080.pdf
著者	山本秀樹\|
出版物タイトル	岡山大学文学部紀要
発行日	2021-12-24
巻	74巻
開始ページ	69
終了ページ	80
ISSN	0285-4864
言語	日本語
論文のバージョン	publisher

Marginal Sufficient Component Cause Model - An Emerging Causal Model With Merits?

フルテキストURL	fulltext20220104-2.pdf
著者	Suzuki, Etsuji\| Yamamoto, Eiji\|
キーワード	Agonism Causality Counterfactual model Mediation Potential outcomes Sufficient cause model
備考	This is a non-final version of an article published in final form in Suzuki, Etsuji; Yamamoto, Eiji Marginal Sufficient Component Cause Model, Epidemiology: November 2021 - Volume 32 - Issue 6 - p 838-845 doi: 10.1097/EDE.0000000000001411\|
発行日	2021-11
出版物タイトル	Epidemiology
巻	32巻
号	6号
出版者	Ovid Technologies (Wolters Kluwer Health)
開始ページ	838
終了ページ	845
ISSN	1044-3983
NCID	AA10832184
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	Copyright © 2021 Wolters Kluwer Health, Inc
論文のバージョン	author
PubMed ID	34583368
DOI	10.1097/ede.0000000000001411
Web of Science KeyUT	000702003900011
関連URL	isVersionOf https://doi.org/10.1097/ede.0000000000001411

Strength in causality: discerning causal mechanisms in the sufficient cause model

フルテキストURL	fulltext20220104-1.pdf
著者	Suzuki, Etsuji\| Yamamoto, Eiji\|
キーワード	Bradford Hill Causal inference Causal mechanisms Counterfactual Sufficient cause model Potential-outcome model
備考	This is an Accepted Manuscript published by Springer Science. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10654-021-00798-6\|
発行日	2021-9
出版物タイトル	European Journal of Epidemiology
巻	36巻
号	9号
出版者	Springer Science and Business Media LLC
開始ページ	899
終了ページ	908
ISSN	0393-2990
NCID	AA10674491
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Springer Nature B.V. 2021
論文のバージョン	author
PubMed ID	34564795
DOI	10.1007/s10654-021-00798-6
Web of Science KeyUT	000700703200003
関連URL	isVersionOf https://doi.org/10.1007/s10654-021-00798-6

Bilateral Optic Disc Swelling as a Plausible Common Ocular Sign of Autoinflammatory Diseases: Report of Three Patients with Blau Syndrome or Cryopyrin-Associated Periodic Syndrome

フルテキストURL	fulltext20211224-1.pdf
著者	Matsuo, Toshihiko\| Yashiro, Masato\| Yamasaki, Osamu\| Tanaka, Takehiro\| Manki, Akira\|
キーワード	autoinflammatory diseases Blau syndrome Muckle-Wells syndrome CINCA/NOMID syndrome cryopyrin-associated periodic syndromes optic disc swelling (optic papillitis)
発行日	2021-12-19
出版物タイトル	Life
巻	11巻
号	12号
出版者	MDPI AG
開始ページ	1433
ISSN	2075-1729
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
DOI	10.3390/life11121433
関連URL	isVersionOf https://doi.org/10.3390/life11121433

「専」に関する墨書土器とその解釈

タイトル（別表記）	Pottery inscribed in ink with the character sen (専) and its interpretation
JaLCDOI	10.18926/63029
フルテキストURL	jdc_001_082.pdf
著者	南健太郎\|
抄録	In this paper, I considered the significance of pottery inscribed in ink with the character sen (専). There are very few examples of such pottery and sen is not believed to have been a commonly used character in ancient society. Sen can be written with a single character or with two or more characters, and in the latter case, the word sentō (専當) is found. The word sentō has the meaning of taking responsibility for a specific task and is also used as the name of a position in the imperial court and at shrines and temples. Especially in the ancient period, it is thought to have been related to duties concerning taxation, duties surrounding the land of temples and shrines, and the duties of manor administrators. The meaning of sentō can be confirmed from examples of its use in historical documents. Based on an analysis of the sites where pottery bearing ink inscriptions of sentō and sen has been unearthed, I suggested that even when the single character sen was used, it had the meaning of sentō.
キーワード	Ancient Japan ink-inscribed pottery Sen (専) Sentō (専當)
Amo Type	研究ノート(Research Notes)
出版物タイトル	文明動態学
発行日	2022-03
巻	1巻
出版者	岡山大学文明動態学研究所
開始ページ	82
終了ページ	91
ISSN	2436-8326
資料タイプ	学術雑誌論文
言語	日本語
著作権者	© 2022 by RIDC
論文のバージョン	publisher
NAID	120007188365

LiDAR測量による岡山県赤磐市鳥取上高塚古墳の墳丘の検討

タイトル（別表記）	Analysis of the Tottori-kamitakatsuka mounded tomb through airborne LiDAR survey
JaLCDOI	10.18926/63028
フルテキストURL	jdc_001_067.pdf
著者	光本順\| 山口雄治\| ライアンジョセフ\|
抄録	This paper presents the results of a drone-based airborne LiDAR survey of the Tottori-kamitakatsuka mounded tomb located in Akaiwa city, Okayama prefecture. Dating to the second half of the Late Kofun period (latter 6th century), this mounded tomb has traditionally been considered either the largest keyhole-shaped mounded tomb in the Bizen area of this period (total length of either 67 m or 75 m) or a round tomb with a diameter of approximately 30 m. Details of the tomb’s size and shape have long been uncertain, owing to the lack of detailed survey mapping of the mound and its environs. In this paper, the authors present their findings on the shape and size of the mounded tomb based on high-quality three-dimensional data acquired through airborne LiDAR survey utilizing a drone; they suggest that the tomb is a keyhole-shaped mounded tomb measuring approximately 75 m in length. This mounded tomb is therefore the second largest mounded tomb of the Kibi region during the period, following the Kōmorizuka mounded tomb located in Sōja city. Additionally, the authors discuss the significance such three-dimensional data has for enhancing our understanding of Japanese history on both a local and archipelago-wide scale.
キーワード	LiDAR survey drone Kofun period Tottori-kamitakatsuka mounded tomb keyhole-shaped mounded tomb
Amo Type	研究ノート(Research Notes)
出版物タイトル	文明動態学
発行日	2022-03
巻	1巻
出版者	岡山大学文明動態学研究所
開始ページ	67
終了ページ	81
ISSN	2436-8326
資料タイプ	学術雑誌論文
言語	日本語
著作権者	© 2022 by RIDC
論文のバージョン	publisher
NAID	120007188366

Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images

フルテキストURL	fulltext20211210-1.pdf
著者	Hamada, Kenta\| Kawahara, Yoshiro\| Tanimoto, Takayoshi\| Ohto, Akimitsu\| Toda, Akira\| Aida, Toshiaki\| Yamasaki, Yasushi\| Gotoda, Tatsuhiro\| Ogawa, Taiji\| Abe, Makoto\| Okanoue, Shotaro\| Takei, Kensuke\| Kikuchi, Satoru\| Kuroda, Shinji\| Fujiwara, Toshiyoshi\| Okada, Hiroyuki\|
キーワード	Artificial intelligence convolutional neural network early gastric cancer endoscopic image invasion depth
備考	This is the peer reviewed version of the following article: [Hamada, K., Kawahara, Y., Tanimoto, T., Ohto, A., Toda, A., Aida, T., Yamasaki, Y., Gotoda, T., Ogawa, T., Abe, M., Okanoue, S., Takei, K., Kikuchi, S., Kuroda, S., Fujiwara, T., and Okada, H. (2021) Application of convolutional neural networks for evaluating the depth of invasion of early gastric cancer based on endoscopic images, Journal of Gastroenterology and Hepatology], which has been published in final form at [https://doi.org/10.1111/jgh.15725]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
発行日	2021-11-25
出版物タイトル	Journal of Gastroenterology and Hepatology
出版者	Wiley
開始ページ	1
ISSN	0815-9319
NCID	AA10727383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd
論文のバージョン	author
PubMed ID	34713495
DOI	10.1111/jgh.15725
Web of Science KeyUT	000722466600001
関連URL	isVersionOf https://doi.org/10.1111/jgh.15725

Meticulous closure of collateral vessels in the perihilar mediastinal pleura to control intraoperative bleeding during lung transplantation for pulmonary hypertension

フルテキストURL	fulltext20211206-4.pdf
著者	Yamamoto, Haruchika\| Sugimoto, Seiichiro\| Imanishi, Kentaro\| Hashimoto, Kohei\| Miyoshi, Kentaroh\| Otani, Shinji\| Yamane, Masaomi\| Toyooka, Shinichi\|
キーワード	Lung transplantation (LT) pulmonary hypertension (PH) collateral vessel bleeding mortality
発行日	2021-10
出版物タイトル	Journal of Thoracic Disease
巻	13巻
号	10号
出版者	AME Publishing Company
開始ページ	5658
終了ページ	5669
ISSN	2072-1439
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Journal of Thoracic Disease
論文のバージョン	publisher
PubMed ID	34795916
DOI	10.21037/jtd-21-1119
Web of Science KeyUT	000717985900010
関連URL	isVersionOf https://doi.org/10.21037/jtd-21-1119

TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment

フルテキストURL	fulltext20211206-3.pdf
著者	Kawashima, Shusuke\| Inozume, Takashi\| Kawazu, Masahito\| Ueno, Toshihide\| Nagasaki, Joji\| Tanji, Etsuko\| Honobe, Akiko\| Ohnuma, Takehiro\| Kawamura, Tatsuyoshi\| Umeda, Yoshiyasu\| Nakamura, Yasuhiro\| Kawasaki, Tomonori\| Kiniwa, Yukiko\| Yamasaki, Osamu\| Fukushima, Satoshi\| Ikehara, Yuzuru\| Mano, Hiroyuki\| Suzuki, Yutaka\| Nishikawa, Hiroyoshi\| Matsue, Hiroyuki\| Togashi, Yosuke\|
発行日	2021-11
出版物タイトル	Journal for ImmunoTherapy of Cancer
巻	9巻
号	11号
出版者	BMJ
開始ページ	e003134
ISSN	2051-1426
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Author(s) (or their employer(s)) 2021.
論文のバージョン	publisher
DOI	10.1136/jitc-2021-003134
Web of Science KeyUT	000720981900005
関連URL	isVersionOf https://doi.org/10.1136/jitc-2021-003134

Liquid Biopsy Targeting Monocarboxylate Transporter 1 on the Surface Membrane of Tumor-Derived Extracellular Vesicles from Synovial Sarcoma

フルテキストURL	K0006452_abstract_review.pdf K0006452_fulltext.pdf K0006452_other1_Supplementary Figure.pdf K0006452_other2_Supplementaly Table 1-1.pdf K0006452_other2_Supplementaly Table 1-2.pdf K0006452_other2_Supplementaly Table 1-3.pdf K0006452_other3_Supplementaly Table 2.pdf K0006452_other4_Supplementaly Table 3.pdf
著者	横尾賢\|
発行日	2021-09-24
資料タイプ	学位論文
学位授与番号	甲第6452号
学位授与年月日	2021-09-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2021 by the authors.

Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression

フルテキストURL	K0006446_abstract_review.pdf K0006446_fulltext.pdf K0006446_other1.pdf
著者	杉生和久\|
発行日	2021-09-24
資料タイプ	学位論文
学位授与番号	甲第6446号
学位授与年月日	2021-09-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021

Unusual aggregation property of recombinantly expressed cancer-testis antigens in mammalian cells

フルテキストURL	fulltext20211118-2.pdf
著者	Ahmadi, Hannaneh\| Shogen, Kohei\| Fujita, Kana\| Honjo, Tomoko\| Kakimi, Kazuhiro\| Futami, Junichiro\|
備考	This is a pre-copyedited, author-produced version of an article accepted for publication in [The Journal of Biochemistry] following peer review. The version of record [Hannaneh Ahmadi, Kohei Shogen, Kana Fujita, Tomoko Honjo, Kazuhiro Kakimi, Junichiro Futami, Unusual aggregation property of recombinantly expressed cancer-testis antigens in mammalian cells, The Journal of Biochemistry, Volume 170, Issue 3, September 2021, Pages 435–443, https://doi.org/10.1093/jb/mvab081] is available online at: https://doi.org/10.1093/jb/mvab081\|
発行日	2021-7-10
出版物タイトル	The Journal of Biochemistry
巻	170巻
号	3号
出版者	Oxford University Press (OUP)
開始ページ	435
終了ページ	443
ISSN	0021-924X
NCID	AA00694073
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Japanese Biochemistry Society
論文のバージョン	author
PubMed ID	34247245
DOI	10.1093/jb/mvab081
Web of Science KeyUT	000711736000013
関連URL	isVersionOf https://doi.org/10.1093/jb/mvab081

Detection of in-frame mutation by IS30-family insertion sequence in the phospholipid phosphatidylglycerol synthase gene (pgsA2) of high-level daptomycin-resistant Corynebacterium striatum

フルテキストURL	fulltext20211109-5.pdf
著者	Gotoh, Kazuyoshi\| Mayura, I. Putu Bayu\| Enomoto, Yusaku\| Iio, Koji\| Matsushita, Osamu\| Otsuka, Fumio\| Hagiya, Hideharu\|
キーワード	Antimicrobial Resistance Daptomycin resistance Corynebacterium striatum Insertion sequence pgsA2 gene
備考	This is an Accepted Manuscript of an article published by Springer. This fulltext is available in Oct. 2022.\|
発行日	2021-10-21
出版物タイトル	European Journal of Clinical Microbiology & Infectious Diseases
巻	41巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	331
終了ページ	333
ISSN	0934-9723
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature
論文のバージョン	author
PubMed ID	34671843
DOI	10.1007/s10096-021-04369-1
Web of Science KeyUT	000709253000001
関連URL	isVersionOf https://doi.org/10.1007/s10096-021-04369-1

Attempt of thyX gene silencing and construction of a thyX deleted clone in a Mycobacterium bovis BCG

フルテキストURL	fulltext20211109-4.pdf
著者	Arimura, Yuki\| Minato, Yusuke\| Wada, Takayuki\| Nakayama, Masaaki\| Ryumon, Ayako\| Hirata, Nao\| Nakajima, Chie\| Suzuki, Yasuhiko\| Ato, Manabu\| Kobayashi, Kazuo\| Ohara, Naoko\| Iida, Seiji\| Ohara, Naoya\|
キーワード	thymidylate synthase ThyX Mycobacterium BCG
備考	This is the peer reviewed version of the following article: [Arimura, Y, Minato, Y, Wada, T, Nakayama, M, Ryumon, A, Hirata, N, et al. Attempt of thyX gene silencing and construction of a thyX deleted clone in a Mycobacterium bovis BCG. Microbiol Immunol. 2021; 1– 5. https://doi.org/10.1111/1348-0421.12944], which has been published in final form at [https://doi.org/10.1111/1348-0421.12944]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\|
発行日	2021-10-21
出版物タイトル	Microbiology and Immunology
巻	66巻
号	1号
出版者	Wiley
開始ページ	10
終了ページ	14
ISSN	0385-5600
NCID	AA00738350
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Societies and John Wiley & Sons Australia, Ltd
論文のバージョン	author
PubMed ID	34546594
DOI	10.1111/1348-0421.12944
Web of Science KeyUT	000709482200001
関連URL	isVersionOf https://doi.org/10.1111/1348-0421.12944

Clinical Efficacy and Safety of Sitafloxacin 200 mg Once Daily for Refractory Genitourinary Tract Infections

JaLCDOI	10.18926/AMO/62820
フルテキストURL	75_6_763.pdf
著者	Iwata, Takehiro\| Sadahira, Takuya\| Maruyama, Yuki\| Sekito, Takanori\| Yoshinaga, Kasumi\| Watari, Shogo\| Nagao, Kentaro\| Kawada, Tatsushi\| Tominaga, Yusuke\| Nishimura, Shingo\| Takamoto, Atsushi\| Sako, Tomoko\| Edamura, Kohei\| Kobayashi, Yasuyuki\| Araki, Motoo\| Ishii, Ayano\| Watanabe, Masami\| Watanabe, Toyohiko\| Nasu, Yasutomo\| Wada, Koichiro\|
抄録	The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants.
キーワード	genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase
Amo Type	Clinical Study Protocol
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	763
終了ページ	766
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955548
Web of Science KeyUT	000735319800006
NAID	120007180272

Pulmonary Enteric Adenocarcinoma Harboring a BRAF G469V Mutation

JaLCDOI	10.18926/AMO/62819
フルテキストURL	75_6_759.pdf
著者	Shimizu, Dai\| Yamamoto, Hiromasa\| Shien, Kazuhiko\| Taniguchi, Kohei\| Miyoshi, Kentaroh\| Namba, Kei\| Mesaki, Kumi\| Sugimoto, Seiichiro\| Soh, Junichi\| Yamane, Masaomi\| Toyooka, Shinichi\|
抄録	Pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of lung cancer that should be differentiated from colorectal cancer metastasis. Little is known about its genetic background. An 84-year-old male with adenocarcinoma of the lung underwent left upper lobectomy. The histology of the surgical specimen was suggestive of PEAC. Gastrointestinal and colorectal fiberscopy revealed no evidence of colorectal cancer. Next-generation sequencing of the tumor identified a G469V substitution in serine/threonine-protein kinase B-raf (BRAF). Based on the higher prevalence of the G469 substitution in BRAF-mutant lung adenocarcinoma than in BRAFmutant colorectal cancer, the tumor likely originated from the lung. Identification of mutational genotype may be of some help in distinguishing PEAC from the lung metastasis of colorectal cancer.
キーワード	non-small cell lung cancer somatic mutations pulmonary adenocarcinoma with enteric differentiation non-V600E BRAF mutation next-generation sequencing
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	759
終了ページ	762
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955547
Web of Science KeyUT	000735319800005
NAID	120007180273

Non-Invasive Prenatal Genetic Testing (NIPT) Leading to Prenatal Diagnosis of Trisomy 21 Mosaicism and 18q Deletion Syndrome: Two Cases

JaLCDOI	10.18926/AMO/62816
フルテキストURL	75_6_745.pdf
著者	Hayata, Kei\| Mishima, Sakurako\| Ohira, Akiko\| Tani, Kazumasa\| Maki, Jota\| Eto, Eriko\| Ogawa, Chikako\| Masuyama, Hisashi\|
抄録	NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results.
キーワード	NIPT massively parallel sequencing trisomy 21 mosaicism 18q-deletion syndrome genetic counseling
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	745
終了ページ	750
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955544
Web of Science KeyUT	000735319800002
NAID	120007180276