| ID | 57367 |
| JaLCDOI | |
| フルテキストURL | |
| 著者 |
Fu, Li
Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Nishibori, Masahiro
Department of Pharmacology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
|
| 抄録 | High mobility group box-1 (HMGB1) is a non-histone, DNA-binding nuclear protein belonging to the family of damage-associated molecular patterns (DAMPs). HMGB1 has been reported to play an important role during epileptogenesis although the mechanisms of its actions are still not clear. Many hypotheses have been suggested especially about the relationship between HMGB1 and inflammation responses and blood-brain barrier disruption during epileptogenesis. In this review, we will mainly discuss the role of HMGB1 in epileptogenesis.
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| キーワード | HMGB1
epileptogenesis
inflammation
blood-brain barrier
|
| Amo Type | Review
|
| 出版物タイトル |
Acta Medica Okayama
|
| 発行日 | 2019-10
|
| 巻 | 73巻
|
| 号 | 5号
|
| 出版者 | Okayama University Medical School
|
| 開始ページ | 383
|
| 終了ページ | 386
|
| ISSN | 0386-300X
|
| NCID | AA00508441
|
| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School
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| 論文のバージョン | publisher
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| 査読 |
有り
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| PubMed ID | |
| Web of Science KeyUT |
