検索結果 1659 件
| タイトル（別表記） | An effective case of peroral endoscopic myotomy for esophageal abnormal peristalsis after Heller-Dor myotomy |
|---|---|
| フルテキストURL | 130_67.pdf |
| 著者 | 杉原 雄策| 原田 馨太| 加藤 諒| 山内 健司| 髙嶋 志保| 山崎 泰史| 井口 俊博| 高原 政宏| 川野 誠司| 平岡 佐規子| 眞部 紀明| 大塚 文男| 岡田 裕之| |
| 抄録 | Esophageal achalasia is a disorder of the lower esophageal sphincter muscle. Our patient, a Japanese male in his 80's, had been experiencing dysphagia for almost 60 years. He was treated with balloon dilations and Heller-Dor 5 years prior to his present admission. Esophagogastroduodenoscopy, esophageal radiography, and high-myotomy manometry indicated that the symptoms were likely due to abnormal peristalsis. With the patient’s informed consent, we performed a peroral endoscopic myotomy（POEM）. The patient was discharged 4 days post-surgery. At the 6-month postoperative examination, no worsening of symptoms or relapse was observed. POEM is an excellent treatment method for esophageal achalasia from the perspective of therapeutic effect. We recommend that POEM be considered as the first-choice treatment for abnormal peristalsis after a Heller-Dor myotomy. |
| キーワード | POEM（peroral endoscopic myotomy） 食道アカラシア（esophageal achalasia） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-08-01 |
| 巻 | 130巻 |
| 号 | 2号 |
| 開始ページ | 67 |
| 終了ページ | 71 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.67 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.67 |
| NAID | 130007481050 |
| JaLCDOI | 10.18926/AMO/56380 |
|---|---|
| フルテキストURL | 72_6_605.pdf |
| 著者 | Mitsui, Yosuke| Sadahira, Takuya| Maruyama, Yuki| Wada, Koichiro| Tanimoto, Ryuta| Sugimoto, Morito| Araki, Motoo| Watanabe, Masami| Yanai, Hiroyuki| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | Metastatic prostate cancer (PCa) cases that cannot be detected on repeat prostate biopsy are extremely rare. Our patient was a 51-year-old Japanese man diagnosed as metastatic PCa by histopathological examination of lesions obtained bone biopsy and lymph node dissection. The primary tumor was not detected after repeated prostate biopsy. Metastatic PCa was diagnosed based on immunohistochemical staining: PSA, AR, P504S, and NKX3.1 of bone and lymph node with metastasis. We speculate that the primary PCa was “burned-out,” demonstrating remote metastases with no apparent primary tumor in the prostate. Burned-out PCa may be difficult to diagnose and treat due to its rarity. |
| キーワード | prostate cancer metastasis unknown primary tumor repeat biopsy CRPC |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-12 |
| 巻 | 72巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 605 |
| 終了ページ | 609 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30573917 |
| NAID | 120006545165 |
| JaLCDOI | 10.18926/AMO/56379 |
|---|---|
| フルテキストURL | 72_6_601.pdf |
| 著者 | Hashimoto, Kazuhiko| Nishimura, Shunji| Iemura, Shunki| Akagi, Masao| |
| 抄録 | Salmonella osteomyelitis is extremely rare; only a few cases have been reported in healthy adults. We describe a case of salmonella osteomyelitis in an otherwise healthy 20-year-old Japanese woman who presented with distal tibial pain. X-ray and magnetic resonance imaging showed a lesion suspected to be a bone cyst. Osteomyelitis was diagnosed when pus was observed during an open biopsy. The bacterial culture examination yielded salmonella. Surgical drainage and antibiotic treatment were performed, after which no recurrence was observed. To our best knowledge, this is the first report of salmonella osteomyelitis of the distal tibia in an otherwise healthy individual. |
| キーワード | osteomyelitis salmonella tibia healthy woman |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-12 |
| 巻 | 72巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 601 |
| 終了ページ | 604 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30573916 |
| NAID | 120006545164 |
| JaLCDOI | 10.18926/AMO/56378 |
|---|---|
| フルテキストURL | 72_6_595.pdf |
| 著者 | Sugihara, Yuusaku| Harada, Keita| Kato, Ryo| Yamauchi, Kenji| Sakae, Hiroyuki| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Fumio| Okada, Hiroyuki| |
| 抄録 | The indications for peroral endoscopic myotomy (POEM) have been expanded to include diffuse esophageal spasm (DES). A 67-year-old Japanese man presented with a 4-year history of dysphagia. Endoscopy and upper gastrography revealed abnormal peristaltic movements involving interruption of normal peristalsis, and a diverticulum located at the 2 o’clock esophageal position. High-resolution manometry indicated DES. POEM with a long (15 cm) myotomy was performed for the abnormal contractions, which subsequently disappeared along with dysphagia improvement. Our results suggest that esophageal motility disorders accompanying a diverticulum may be eliminated by POEM without treating the diverticulum itself. We speculate that POEM ameliorates esophageal diverticulum by reducing internal esophageal pressure. |
| キーワード | diffuse esophageal spasm (DES) diverticulum, peroral endoscopic myotomy (POEM) high-resolution manometry (HRM) |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-12 |
| 巻 | 72巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 595 |
| 終了ページ | 600 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30573915 |
| NAID | 120006545163 |
| JaLCDOI | 10.18926/AMO/56253 |
|---|---|
| フルテキストURL | 72_5_531.pdf |
| 著者 | Kondo, Naoki| Fujisawa, Junichi| Arai, Katsumitsu| Kakutani, Rika| Endo, Naoto| |
| 抄録 | A 60-year-old Japanese woman with severe osteoporosis presented with a history of right buttock pain and right lateral lower leg pain in an L5 distribution. She had been treated with methotrexate and methylprednisolone for rheumatoid arthritis (RA) and interstitial pneumonia. Computed tomography demonstrated a sacral stress fracture in the right sacral ala. The right L5 nerve root was compressed by the fracture site. This case is rare in that L5 radiculopathy was complicated by a sacral stress fracture. Clinicians should suspect sacral stress fractures when RA or osteoporosis is present in women who experiences lumbar pain and lumbar radiculopathy. |
| キーワード | lumbar 5 radiculopathy sacral stress fracture osteoporosis rheumatoid arthritis |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-10 |
| 巻 | 72巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 531 |
| 終了ページ | 534 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30369612 |
| JaLCDOI | 10.18926/AMO/56252 |
|---|---|
| フルテキストURL | 72_5_525.pdf |
| 著者 | Kakutani, Rika| Kondo, Naoki| Mochizuki, Tomoharu| Fujisawa, Junichi| Endo, Naoto| |
| 抄録 | The bilateral shoulder pain of an 81-year-old Japanese woman due to falls persisted despite celecoxib treatment, and plain X-rays later showed bilateral collapsed humeral heads. After ruling out osteoarthritis, infectious arthritis, crystal-induced arthritis, neuropathic arthropathy, and osteonecrosis, we diagnosed bilateral shoulder joint rapidly destructive arthrosis (RDA). Lumbar bone mineral density showed very low T-score (−4.1). Primary osteoporosis was observed. Histology of biopsied humeral head indicated the features of fracture healing process: callus formation and osteoclasts without empty lacunae. Her history thus included an insufficiency fracture due to severe osteoporosis. Bilateral humeral head replacement was performed; her shoulder joint function improved. This case is extremely rare in that RDA was caused by simultaneous bilateral shoulder joint collapse within a very short time, with minimal or low mechanical stress and severe osteoporosis. |
| キーワード | rapidly destructive arthrosis differential diagnosis humeral head replacement osteoporosis shoulder joint |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-10 |
| 巻 | 72巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 525 |
| 終了ページ | 530 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30369611 |
| JaLCDOI | 10.18926/AMO/56251 |
|---|---|
| フルテキストURL | 72_5_519.pdf |
| 著者 | Miyahara, Hiroyuki| Tokumasu, Hironobu| Chin, Masaki| Waki, Kenji| Arakaki, Yoshio| |
| 抄録 | Cases of recurrent meningitis in elderly patients with a spontaneous cerebrospinal fistula have been reported, and in some of these patients, cystic lesions were thought to be the underlying cause. We report a case of recurrent meningitis in an 11-year-old Japanese girl with an arachnoid cyst in the petrous apex. Pulsation of the cystic lesion was thought to cause bone erosion, leading to the formation of a fistula. Magnetic resonance imaging was useful in evaluating the arachnoid cyst and fistula. During 2 years of follow-up, the osteolytic lesion enlarged and the rate of bone erosion was higher than expected. |
| キーワード | magnetic resonance imaging pulsation of cystic lesion bone erosion fistula |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-10 |
| 巻 | 72巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 519 |
| 終了ページ | 523 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30369610 |
| JaLCDOI | 10.18926/AMO/56250 |
|---|---|
| フルテキストURL | 72_5_515.pdf |
| 著者 | Kanamitsu, Kiichiro| Chayama, Kousuke| Washio, Kana| Yoshida, Ryuichi| Umeda, Yuzo| Yagi, Takahito| Shimada, Akira| |
| 抄録 | Hepatitis-associated aplastic anemia (HAAA) is an acquired bone marrow failure syndrome that develops after seronegative fulminant hepatitis. Abnormal cytotoxic T-cell activation with cytokine release is a possible pathophysiology. We present the case of a 16-month-old Japanese male who developed HAAA following living-donor liver transplantation for fulminant hepatitis. His aplastic anemia was successfully treated with immunosuppressive therapy. He had been administered tacrolimus for prophylaxis against hepatic allograft rejection. Ten years after the HAAA onset, the patient’s bone marrow was found to be slightly hypoplastic. Tacrolimus may be effective in controlling abnormal immune reactions that can cause recurrent impaired hematopoiesis. |
| キーワード | hepatitis-associated aplastic anemia impaired hematopoiesis liver transplantation immunosuppressive therapy abnormal immune reaction |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-10 |
| 巻 | 72巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 515 |
| 終了ページ | 518 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30369609 |
| フルテキストURL | Gerodontology_34_1_129.pdf |
|---|---|
| 著者 | Kobayashi, Naoki| Soga, Yoshihiko| Maekawa, Kyoko| Kanda, Yuko| Kobayashi, Eiko| Inoue, Hisako| Kanao, Ayana| Himuro, Yumiko| Fujiwara, Yumi| |
| キーワード | dementia hospital care mouth risk management |
| 備考 | This is an Accepted Manuscript of an article published by John Wiley| |
| 発行日 | 2017-03 |
| 出版物タイトル | Gerodontology |
| 巻 | 34巻 |
| 号 | 1号 |
| 出版者 | John Wiley |
| 開始ページ | 129 |
| 終了ページ | 134 |
| ISSN | 0734-0664 |
| NCID | AA10450927 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 27207609 |
| DOI | 10.1111/ger.12235 |
| Web of Science KeyUT | 000394951200016 |
| 関連URL | isVersionOf https://doi.org/10.1111/ger.12235 |
| JaLCDOI | 10.18926/AMO/56181 |
|---|---|
| フルテキストURL | 72_4_419.pdf |
| 著者 | Miyake, Susumu| Sugita, Makio| Okazaki, Tomio| Takenaka, Mieko| Kuwabara, Kentarou| Ogawa, Kazunori| |
| 抄録 | A 22-year-old Japanese male with trisomy 21 was diagnosed with West syndrome at 4 months old. After the suppression of epileptic spasms using adrenocorticotropic hormone therapy, he had complex partial seizures and bilateral frontal epileptic discharges on EEG. Although the introduction of topiramate (TPM) decreased the seizures during wakefulness, frequent episodes of brief eye-opening appeared during sleep while the patient was taking TPM (400 mg/day). EEG showed fast activity at the times of eye-opening. The episodes of eye-opening during sleep and the fast activities disappeared upon TPM discontinuation. This is the first report of TPM-induced microseizures similar to benzodiazepine-induced microseizures. |
| キーワード | topiramate microseizures paroxysmal fast activity side effects seizure aggravation |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-08 |
| 巻 | 72巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 419 |
| 終了ページ | 422 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30140091 |
| JaLCDOI | 10.18926/AMO/56172 |
|---|---|
| フルテキストURL | 72_4_369.pdf |
| 著者 | Iwamoto, Takayuki| Taira, Naruto| Fujisawa, Tomomi| Araki, Kazuhiro| Sakamaki, Kentaro| Sangai, Takafumi| Kikawa, Yuichiro| Shien, Tadahiko| Takao, Shintaro| Sato, Masako| Goto, Yoshinari| Yoshida, Takashi| Takahashi, Masato| Aihara, Tomohiko| Mukai, Hirofumi| |
| 抄録 | The Hormonal therapy resistant estrogen-receptor positive metastatic breast cancer cohort (HORSE-BC) study is a multicenter observational study evaluating the efficacy and safety of secondary endocrine therapy (ET) for postmenopausal cases of metastatic breast cancer (MBC) with poor response to primary ET. In this initial report we analyze the HORSE-BC baseline data to clarify the current status of treatment selection for MBC in Japan. Baseline data for the 50 patients enrolled in HORSE-BC were analyzed, including patient characteristics, types of secondary ET, and reasons for selecting secondary ET. Postoperative recurrence was detected in 84% of patients (42/50) and de novo stage IV breast cancer in 16% (8/50). Forty-one patients (41/50; 82%) received fulvestrant, 5 patients (10%) received selective estrogen receptor modulators (SERMs), 3 patients (6%) received ET plus a mammalian target of rapamycin (mTOR) inhibitor, and 1 patient received an aromatase inhibitor (AI) as the secondary ET. Forty-five patients selected their secondary ET based on its therapeutic effect, while 14 patients selected it based on side effects. Most patients with progression after primary ET selected fulvestrant as the secondary ET based on its therapeutic and side effects. We await the final results from the HORSE-BC study. |
| キーワード | breast cancer secondary endocrine therapy low sensitivity primary endocrine therapy fulvestrant |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-08 |
| 巻 | 72巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 369 |
| 終了ページ | 374 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 30140084 |
| JaLCDOI | 10.18926/AMO/56078 |
|---|---|
| フルテキストURL | 72_3_309.pdf |
| 著者 | Katayama, Satoshi| Takenaka, Tadasu| Nakamura, Aya| Sako, Sinichi| Bessho, Akihiro| Ohara, Nobuya| |
| 抄録 | Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal, malignancy-related respiratory complication; we herein report a PTTM case induced by metastatic prostate cancer. An 81-year-old Japanese man developed dyspnea. High-resolution computed tomography (HRCT) revealed ground-glass opacities spread across bilateral lung fields. Pulmonary microvascular aspiration cytology detected prostate cancer cells. As PTTM was highly suspected, docetaxel chemotherapy was performed immediately. His respiratory condition and HRCT findings improved temporarily, but he died approx. 6 weeks after admission. Autopsy showed fibrocellular intimal proliferation of small pulmonary arterioles, which confirmed the diagnosis of PTTM induced by prostate cancer. As in the present case, it is often difficult to confirm the presence of not only tumor embolization but also fibrocellular intimal proliferation before the patient’s death. |
| キーワード | autopsy dyspnea prostate neoplasm metastatic lung cancer thrombotic microangiopathy |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-06 |
| 巻 | 72巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 309 |
| 終了ページ | 313 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29926010 |
| JaLCDOI | 10.18926/AMO/56077 |
|---|---|
| フルテキストURL | 72_3_301.pdf |
| 著者 | Kakio, Yuki| A. Uchida, Haruhito| Kitagawa, Masashi| Arata, Yuka| Kato, Ayako| Inoue-Torii, Akiko| Hinamoto, Norikazu| Ogawa-Akiyama, Ayu| Sugiyama, Hitoshi| Wada, Jun| |
| 抄録 | Renal involvement is occasionally observed in Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT). It has been reported that galactose-deficient IgA is a closely linked to IgA nephropathy (IgAN), suggesting that patients with XLT/WAS associated with reduced galactosylation on serum IgA are susceptible to IgAN. It is necessary to pay more attention to patients with IgAN due to the potential complication with XLT/WAS. We here present a patient of XLT complicated with mild IgAN who underwent tonsillectomy combined with steroid pulse therapy to achieve complete clinical remission. |
| キーワード | IgAN nephropathy Wiskott-Aldrich syndrome X-linked thrombocytopenia galactose-deficient IgA1 |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-06 |
| 巻 | 72巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 301 |
| 終了ページ | 307 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29926009 |
| JaLCDOI | 10.18926/AMO/56076 |
|---|---|
| フルテキストURL | 72_3_297.pdf |
| 著者 | Yamamoto, Hirotsugu| Naito, Hiromichi| Osako, Takaaki| Tsukahara, Kohei| Yamada, Taihei| Yumoto, Tetsuya| Iida, Atsuyoshi| Kosaki, Yoshinori| Oka, Makio| Endo, Fumika| Gochi, Akira| Nakao, Atsunori| |
| 抄録 | A healthy 10-year-old boy vomited during sleep and later complained of abdominal pain; he became drowsy and uncommunicative. At the nearby hospital E.R., he deteriorated rapidly, and his respiratory movements were absent with cardiac arrest. He was immediately resuscitated. Brain MRI showed no abnormalities. EEG revealed an abnormal pattern with recurrent multifocal epileptiform activity over the bilateral occipital and frontal regions during sleep. Based on the clinical/radiological findings we diagnosed Panayiotopoulos syndrome (PS), a benign form of early-onset pediatric epilepsy characterized by autonomic symptoms. Lifethreating cardiopulmonary arrest is rare in PS, but long seizure duration of PS may associate with apnea and bradycardia. |
| キーワード | pediatric epilepsy autonomic symptom cardiac arrest afebrile seizure EEG |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-06 |
| 巻 | 72巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 297 |
| 終了ページ | 300 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29926008 |
| タイトル（別表記） | Metaplastic carcinoma of the breast : Two cases |
|---|---|
| フルテキストURL | 130_19.pdf |
| 著者 | 元木 崇之| 岩本 高行 | 大森 昌子| 松岡 順治| |
| 抄録 | We treated two patients with a rare metaplastic carcinoma of the breast. Patient 1：A 32-year-old woman presented with a rapidly growing mass（ 7cm） in her right breast. We diagnosed cT3N0M0 Stage IIB breast cancer and performed a radical resection. The pathological diagnosis was triple-negative metaplastic carcinoma with a Ki-67 value ＞30%. Postoperative adjuvant chemotherapy and radiotherapy were performed. Patient 2：A 66-year-old postmenopausal woman presented with a left breast mass. We diagnosed cT1N0M0 Stage I breast cancer and performed a radical resection. The pathological diagnosis was triple-negative metaplastic carcinoma with a Ki-67 value ＞30%. Postoperative adjuvant chemotherapy was performed. Patients 1 and 2 have achieved relapse-free survivals of 1 year＋2 months and 10 months, respectively. Metaplastic carcinoma of the breast is a rare tumor, and its prognosis is not favorable. The only available treatment is that used for invasive ductal carcinoma；a more specific treatment has not been established. The accumulation of further similar cases and the development of a novel effective treatment are desired. |
| キーワード | 乳癌（breast cancer） 化生癌（metaplastic carcinoma） 化学療法（chemotherapy） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-04-02 |
| 巻 | 130巻 |
| 号 | 1号 |
| 開始ページ | 19 |
| 終了ページ | 23 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.13 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.13 |
| NAID | 130006730866 |
| タイトル（別表記） | A case of a mesenteric desmoid tumor preoperatively distinguished from imaging findings |
|---|---|
| フルテキストURL | 130_13.pdf |
| 著者 | 河合 毅| 渡邉 貴紀| 信久 徹治 | 松本 祐介| 甲斐 恭平| 佐藤 四三| |
| 抄録 | A 73-year-old woman was admitted for closer investigation into an abdominal tumor. Abdominal ultra-sonography, CT, and magnetic resonance imaging showed a discrete abdominal tumor. Especially on MRI, the tumor appeared as a relatively ill-defined whorled soft-tissue thickening within the mesenteric fat, causing angulation or speculation of adjacent bowel mesentery. Surgery was performed under a presumptive diagnosis of a mesojejunum desmoid. The tumor was invading the transverse mesocolon and mesojejunum as well as the third portion of the duodenum and the middle colic artery, and it was close to but apart from the superior mesenteric artery. The tumor was resected, including removal of part of the duodenum and transverse colon. The specimen contained a white solid tumor measuring 14×12×8cm. Pathologic examination showed differentiated fibroblasts and copious collagen fibers. The tumor was negative for CD34, c-kit, S-100, and α-SMA, but positive for β-catenin. On the basis of these findings, we established a diagnosis of mesenteric desmoid tumor of the small intestine. The patient has been followed postoperatively for 2 years, no sign of recurrence, to date. |
| キーワード | 小腸間膜 (mesentery of the small intestine) デスモイド (desomoid) 腸間膜腫瘍 (mesenteric tumor) |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-04-02 |
| 巻 | 130巻 |
| 号 | 1号 |
| 開始ページ | 13 |
| 終了ページ | 18 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.13 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.13 |
| NAID | 130006730865 |
| JaLCDOI | 10.18926/AMO/55861 |
|---|---|
| フルテキストURL | 72_2_189.pdf |
| 著者 | Nakao, Shinichiro| Hagiya, Hideharu| Kimura, Keigo| Mitsui, Tomomi| Oyama, Akane| Hongyo, Kazuhiro| Takahashi, Yusuke| Nakagami, Futoshi| Tomono, Kazunori| Rakugi, Hiromi| |
| 抄録 | A 65-year-old Japanese man with bilateral carotid atherosclerosis presented with right neck pain and fever. Contrast-enhanced computed tomography suggested carotid arteritis, and carotid ultrasonography showed an unstable plaque. The patient developed a cerebral embolism, causing a transient ischemic attack. Helicobacter cinaedi was detected in blood culture, and H. cinaedi-associated carotid arteritis was diagnosed. Empirical antibiotic therapy was administered for 6 weeks. After readmission for recurrent fever, he was treated another 8 weeks. Although the relationship between H. cinaedi infection and atherosclerosis development remains unclear, the atherosclerotic changes in our patient’s carotid artery might have been attributable to H. cinaedi infection. |
| キーワード | atherosclerosis bacteremia bacterial translocation Helicobacter cinaedi vascular infection |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-04 |
| 巻 | 72巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 189 |
| 終了ページ | 192 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29674769 |
| JaLCDOI | 10.18926/AMO/55860 |
|---|---|
| フルテキストURL | 72_2_185.pdf |
| 著者 | Morizane, Shin| Sugimoto, Saeko| Motoki, Takayuki| Katayama, Norihisa| Omori, Masako| Iwatsuki, Keiji| |
| 抄録 | Psoriasis is a common chronic inflammatory skin disorder that is characterized by scaly, erythematous, sharply demarcated plaques. The treatment for psoriasis has dramatically changed over the last 10 years with the introduction of biologics. However, the risk of cancer induced by biologics for psoriasis has not been fully analyzed, since these agents have such a short history of use. Here we report the case of a 74-year-old woman with psoriasis vulgaris and psoriatic arthritis complicated by breast cancer after systemic treatments including etretinate, cyclosporine, methotrexate, adalimumab, and ustekinumab. |
| キーワード | psoriasis systemic therapy biologics malignancy |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-04 |
| 巻 | 72巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 185 |
| 終了ページ | 187 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29674768 |
| JaLCDOI | 10.18926/AMO/55859 |
|---|---|
| フルテキストURL | 72_2_181.pdf |
| 著者 | Tsuboi, Chika| Naito, Hiromichi| Hagioka, Shingo| Hanafusa, Hiroaki| Hirayama, Takahiro| Kosaki, Yoshinori| Iida, Atsuyoshi| Yumoto, Tetsuya| Tsukahara, Kohei| Morimoto, Naoki| Nakao, Atsunori| |
| 抄録 | The primary toxicity of hydrogen peroxide results from its interaction with catalase, which liberates water and oxygen. We report the case of a 14-year-old Japanese girl with portal venous gas that was caused by oxygen liberated from intentionally ingested hydrogen peroxide. Although she had a past history of atrial septal defect, recovery without cardiac or neurological sequelae was achieved using hyperbaric oxygen therapy. Emergency physicians must be aware of the danger of liberated oxygen due to hydrogen peroxide ingestion. |
| キーワード | air embolism ASD breaching agent HBO intoxication |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-04 |
| 巻 | 72巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 181 |
| 終了ページ | 183 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29674767 |
| JaLCDOI | 10.18926/AMO/55849 |
|---|---|
| フルテキストURL | 72_2_99.pdf |
| 著者 | Sugihara, Yuusaku| Harada, Keita| Kato, Ryo| Yamauchi, Kenji| Takashima, Shiho| Takei, Daisuke| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki| |
| 抄録 | Peroral endoscopic myotomy (POEM) for treatment of esophageal motility disorders has recently been reported to be highly effective and less invasive than other treatment. POEM was recently introduced in Okayama University Hospital under the supervision of a physician from a high-volume center. To verify the safety and efficacy of POEM during its introduction in our institution. We examined 10 cases in whom POEM was performed between January 2016 and April 2017. The patients included 7 men and 3 women, with a median age (range) of 49 years (17-74) and median symptom duration of 6 years (1-21). Seven patients had a straight esophagus, and the remaining 3 had a sigmoid esophagus. According to the Chicago classification, 6 patients were diagnosed with type I achalasia, 2 with type II achalasia, and 2 with distal esophagus spasm. Treatment outcomes and adverse events were evaluated. Treatment success was defined as a > 3 decrease in Eckardt score or a score of <3 at the time of discharge. The treatment success rate was 90%, with the average Eckardt score decreasing significantly, from 4.7 to 0.9 (p<0.05). No mucosal perforation, severe infection, mediastinitis, severe bleeding, or gastroesophageal reflux occurred intraoperatively or postoperatively. POEM was introduced to Okayama University Hospital, and the first 10 cases were accomplished safely and effectively under the supervision of an expert physician from a high-volume center. |
| キーワード | achalasia Eckardt score peroral endoscopic myotomy (POEM) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-04 |
| 巻 | 72巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 99 |
| 終了ページ | 104 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29674757 |