検索結果 1659 件
JaLCDOI | 10.18926/AMO/58276 |
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フルテキストURL | 74_2_165.pdf |
著者 | Umemura, Hiroshi| Miura, Katsuhiro | Naruse, Hiromu| Hatta, Yoshihiro| Takei, Masami| Nakayama, Tomohiro| |
抄録 | Hereditary hemorrhagic telangiectasia (HHT; also known as Osler-Weber-Rendu disease) is an autosomal dominant genetic disorder that causes frequent epistaxis, mucocutaneous telangiectasia, and visceral arteriovenous malformations. Four genes (ENG, ACVRL1, SMAD4, and GDF2) have been identified as pathogenic in HHT. We describe the case of a 50-year-old Japanese man highly suspected of having HHT due to recurrent epistaxis, mucocutaneous telangiectasia, and a family history. Genomic analysis revealed a novel missense mutation of c.100T>A, p.Cys34Ser in the patient’s ACVRL1 gene. We used 6 freeware programs to perform an in silico analysis of this mutation. The results demonstrated the mutation’s high pathogenicity. |
キーワード | ACVRL1 hereditary hemorrhagic telangiectasia in silico analysis missense mutation Osler-Weber- Rendu disease |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-04 |
巻 | 74巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 165 |
終了ページ | 169 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32341592 |
Web of Science KeyUT | 000528278500011 |
NAID | 120006839455 |
JaLCDOI | 10.18926/AMO/58275 |
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フルテキストURL | 74_2_159.pdf |
著者 | Thar Htet San| Ota, Yoko| Fushimi, Soichiro| Fujisawa, Masayoshi| Yanai, Hiroyuki| Toda, Hiroko| Kunitomo, Tadayoshi| Kodama, Keisuke| Matsukawa, Akihiro| |
抄録 | Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (~97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested. |
キーワード | juvenile granulosa cell tumor late recurrence adult granulosa cell tumor |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-04 |
巻 | 74巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 159 |
終了ページ | 163 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32341591 |
Web of Science KeyUT | 000528278500010 |
NAID | 120006839454 |
JaLCDOI | 10.18926/AMO/58274 |
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フルテキストURL | 74_2_151.pdf |
著者 | Yamamoto, Norio| Dan’ura, Tomoyuki| Noda, Tomoyuki| Ozaki, Toshifumi| |
抄録 | This is the second report of an atypical peri-implant femoral fracture occurring at the distal screw after intramedullary nail fixation of a pertrochanteric fracture. A 94-year-old Japanese female with a 5-year history of alendronate intake presented with prodromal pain in her right thigh after intramedullary nail fixation. Plain radiographs showed an incomplete noncomminuted transverse fracture at the distal screw, suggesting an atypical peri-implant femoral fracture. The pathogenesis of an atypical peri-implant femoral fracture could be a combined systemic bone metabolism disorder and repetitive overloading at the screw, similar to the pathogenesis of an atypical periprosthetic femoral fracture around stem implantation. |
キーワード | atypical femoral fracture insufficiency fracture bisphosphonate atypical peri-implant femoral fracture, atypical periprosthetic femoral fracture |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-04 |
巻 | 74巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 151 |
終了ページ | 157 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32341590 |
Web of Science KeyUT | 000528278500009 |
NAID | 120006839453 |
JaLCDOI | 10.18926/AMO/58272 |
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フルテキストURL | 74_2_137.pdf |
著者 | Isozaki, Hiroshi| Yamamoto, Yasuhisa| Sakai, Kunihiko| Sho, Tatuo| Ishihara, Kiyohiro| Murakami, Shigeki| Matsumoto, Sasau| Takama, Takehiro| |
抄録 | Mucinous carcinoma (MC) of the breast is a rare and special type of malignancy, with a substantial amount of extracellular mucin. We compared the clinicopathological features and the long-term survival of MC patients with those of invasive ductal carcinoma-no special type (IDC-NST) patients, and we examined prognostic factors of MC. A total of 116 patients with mucinous carcinoma and 3,258 patients with IDC-NST who underwent surgery at our hospital (1977-2008) were enrolled. The 10-year overall survival rate and breast cancer-specific survival rate (BSS) of the MC patients (88.3%, 93.7%) were both significantly higher than those of IDC-NST patients (81.6%, 85.0%) (p=0.015, p=0.005, respectively). A Cox regression analysis demonstrated that MC tended to be an independent prognostic factor (hazard ratio 0.44, p=0.098). The BSS of the MC patients with positive lymph node (LN) metastasis was significantly poorer than that of the patients without it, by univariate analysis (p=0.002). The tumor size in the MC patients with positive LN metastasis (mean 3.2 cm) was significantly larger than that in the patients without it (mean 1.9 cm) (p=0.0004). Although a Cox regression analysis revealed no independent factor, MC patients with positive LN metastasis should be treated for advanced invasive ductal breast cancer. |
キーワード | breast cancer mucinous carcinoma clinicopathological features long-term prognosis |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-04 |
巻 | 74巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 137 |
終了ページ | 143 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32341588 |
Web of Science KeyUT | 000528278500007 |
NAID | 120006839451 |
フルテキストURL | fulltext.pdf figs.pdf tables.pdf |
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著者 | Itano, Junko| Higo, Hisao| Ohashi, Kadoaki| Makimoto, Go| Nishii, Kazuya| Hotta, Katsuyuki| Miyahara, Nobuaki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
キーワード | osimertinib drug-induced ILD reversed halo sign organizing pneumonia pattern re-administration |
発行日 | 2020-03-15 |
出版物タイトル | Internal Medicine |
巻 | 59巻 |
号 | 6号 |
出版者 | The Japanese Society of Internal Medicine |
開始ページ | 823 |
終了ページ | 828 |
ISSN | 0918-2918 |
NCID | AA10827774 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2020 by The Japanese Society of Internal Medicine |
論文のバージョン | author |
PubMed ID | 31787696 |
DOI | 10.2169/internalmedicine.3689-19 |
Web of Science KeyUT | 000521137500011 |
関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.3689-19 |
フルテキストURL | fulltext.pdf |
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著者 | Makihara, Seiichiro| Kariya, Shin| Naito, Tomoyuki| Uraguchi, Kensuke| Matsumoto, Junya| Noda, Yohei| Okano, Mitsuhiro| Nishizaki, Kazunori| |
キーワード | Negative pressure wound therapy false vocal cord perforation deep neck abscess larynx perforation head and neck fistula |
発行日 | 2020-04-02 |
出版物タイトル | SAGE Open Medical Case Reports |
巻 | 8巻 |
出版者 | SAGE Publications |
開始ページ | 2050313X20915415 |
ISSN | 2050-313X |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2020 |
論文のバージョン | publisher |
DOI | 10.1177/2050313X20915415 |
Web of Science KeyUT | 000523514000001 |
関連URL | isVersionOf https://doi.org/10.1177/2050313X20915415 |
フルテキストURL | fulltext.pdf |
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著者 | Tsuge, Mitsuru| Miyamoto, Machiko| Miyawaki, Reiji| Kondo, Yoichi| Tsukahara, Hirokazu| |
キーワード | Child Hemophagocytic lymphohistiocytosis Invasive pneumococcal disease Pneumococcal conjugate vaccine Serotype replacement |
発行日 | 2020-01-13 |
出版物タイトル | BMC Pediatrics |
巻 | 20巻 |
号 | 1号 |
出版者 | BMC |
ISSN | 1471-2431 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s). 2020 |
論文のバージョン | publisher |
PubMed ID | 31931763 |
DOI | 10.1186/s12887-020-1915-7 |
Web of Science KeyUT | 000514577300003 |
関連URL | isVersionOf https://doi.org/10.1186/s12887-020-1915-7 |
フルテキストURL | fulltext.pdf |
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著者 | Suzuki, Yoko| Taniguchi, Kohei| Hatono, Minami| Kajiwara, Yukiko| Abe, Yuko| Kawada, Kengo| Tsukioki, Takahiro| Kochi, Mariko| Nishiyama, Keiko| Iwamoto, Takayuki| Ikeda, Hirokuni| Shien, Tadahiko| Taira, Naruto| Tabata, Masahiro| Yanai, Hiroyuki| Doihara, Hiroyoshi| |
キーワード | Radiation-induced angiosarcoma Radiotherapy Breast-conserving surgery Breast cancer Paclitaxel therapy Adjuvant therapy of angiosarcoma |
発行日 | 2020-01-16 |
出版物タイトル | Surgical Case Reports |
巻 | 6巻 |
号 | 1号 |
出版者 | SpringerOpen |
開始ページ | 25 |
ISSN | 2198-7793 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s). 2020 |
論文のバージョン | publisher |
PubMed ID | 31950295 |
DOI | 10.1186/s40792-020-0790-7 |
Web of Science KeyUT | 000513920900001 |
関連URL | isVersionOf https://doi.org/10.1186/s40792-020-0790-7 |
フルテキストURL | fulltext.pdf |
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著者 | Yamamoto, Haruchika| Miyoshi, Kentaroh| Otani, Shinji| Kurosaki, Takeshi| Sugimoto, Seiichiro| Yamane, Masaomi| Toyooka, Shinichi| Kobayashi, Motomu| Oto, Takahiro| |
キーワード | Inverted lung transplantation Pericardial conduit Pulmonary venous anastomosis Vessel formation |
発行日 | 2020-02-19 |
出版物タイトル | BMC Pulmonary Medicine |
巻 | 20巻 |
号 | 1号 |
出版者 | BMC |
開始ページ | 46 |
ISSN | 1471-2466 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s). 2020 |
論文のバージョン | publisher |
PubMed ID | 32075616 |
DOI | 10.1186/s12890-020-1075-4 |
Web of Science KeyUT | 000517294200001 |
関連URL | isVersionOf https://doi.org/10.1186/s12890-020-1075-4 |
フルテキストURL | fulltext.pdf |
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著者 | Eto, Eriko| Mitsui, Takashi| Tamada, Shoko| Maki, Jota| Hayata, Kei| Masuyama, Hisashi| |
キーワード | adrenal incidental tumor pregnancy subclinical Cushing's syndrome superimposed preeclampsia |
発行日 | 2020-02-03 |
出版物タイトル | Clinical Case Reports |
巻 | 8巻 |
号 | 3号 |
出版者 | Wiley |
開始ページ | 481 |
終了ページ | 483 |
ISSN | 2050-0904 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2020 The Authors. |
論文のバージョン | publisher |
PubMed ID | 32185040 |
DOI | 10.1002/ccr3.2592 |
Web of Science KeyUT | 000519370400016 |
関連URL | isVersionOf https://doi.org/10.1002/ccr3.2592 |
タイトル(別表記) | Emergency medical treatment of patients undergoing otolaryngology in the southeastern part of Okayama Prefecture |
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フルテキストURL | 131_145.pdf |
著者 | 秋定 直樹| 石原 久司| 宇野 雅子| 赤木 祐介| 梶原 壮平| 福本 晶| 若林 時生| 竹内 彩子| 秋定 健| |
抄録 | To clarify the scenario regarding the emergency medical treatment of patients undergoing otolaryngology in southeastern Okayama Prefecture in Japan, we evaluated the conditions in three hospitals that mainly provide emergency medical treatment to patients undergoing otorhinolaryngology at night or on holidays. The data (age, sex, type of disease, and address) of patients who visited Japanese Red Cross Okayama Hospital, Kawasaki Medical School General Medical Center, and Okayama Medical Center in 2018 were collected and compared. All three hospitals reported many cases of tonsillar abscess and nasal bleeding. In the study population, the number of patients aged ≤10 and 10-20 years were the lowest and highest, respectively. Patients residing in southern Okayama City and Tamano City tended to visit Japanese Red Cross Okayama Hospital or Kawasaki Medical School General Medical Center. Patients residing in northeastern Okayama Prefecture and northern Okayama City tended to visit Okayama Medical Center. A ceiling for the senior physicians’ capacity will be introduced in April 2020, and thus the number of otolaryngology-related treatments performed in Okayama Prefecture is expected to decrease. The otolaryngologyrelated emergency medical treatment in southeastern Okayama Prefecture may collapse. Emergency medical care systems must therefore be considered in the future. |
キーワード | 耳鼻咽喉科 (otolaryngology) 救急体制 (emergency system) 働き方改革 (work style reform) 専門医制度 (specialist system) 地域医療 (regional medical care) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2019-12-02 |
巻 | 131巻 |
号 | 3号 |
開始ページ | 145 |
終了ページ | 152 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.131.145 |
言語 | 日本語 |
著作権者 | Copyright (c) 2019 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.131.145 |
NAID | 130007782629 |
JaLCDOI | 10.18926/CTED/58131 |
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タイトル(別表記) | Childcare Practice Study of Rythmique that Draws Proactive Physical Expression from Children (1st Report) : Mainly Including Cases of Classes for One, Two, and Three Years Old in a Childcare Facility |
フルテキストURL | cted_010_183_197.pdf |
著者 | 小竹 沙織| 馬場 訓子| 髙橋 慧| 渡邊 祐三| 髙橋 敏之| |
抄録 | 近年の先行研究を「身体表現」「音楽教育」「リトミック」「遊戯」をキーワードに概観すると,100 年を超える歴史の中で,リトミックの捉え方が変容していることと,リトミックの新しい保育実践研究が必要であることが,明らかになった。そこで本論では,保育施設におけるリトミックの実践から,子どもが何を学び,何が育っているのかを論考した。その結果,以下のことが示唆された。(1)1歳児学級の子どもは,保育者の模倣を活発に行う段階である。(2)2歳児学級においては,子どもが自由に想像し表現できるよう,保育者は,配慮する必要がある。(3)3歳児学級においては,表現することの楽しさを通して心が解放される気持ち良さを感じることや,リトミックの主題や保育者の姿に集中することや,何かを達成する喜びを感じること等が重要である。 |
キーワード | 子ども (Child (Children)) 身体表現 (Physical expression) リトミック (Rythmique) 保育実践 (Childcare practice) 1・2・3歳児学級 (Classes for One, Two, and Three Years Old) |
出版物タイトル | 岡山大学教師教育開発センター紀要 |
発行日 | 2020-03-20 |
巻 | 10巻 |
開始ページ | 183 |
終了ページ | 197 |
ISSN | 2186-1323 |
言語 | 日本語 |
著作権者 | Copyright © 2020 岡山大学教師教育開発センター |
論文のバージョン | publisher |
フルテキストURL | fulltext.pdf |
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著者 | Makimoto, Go| Ohashi, Kadoaki| Taniguchi, Kohei| Soh, Junichi| Taniguchi, Akihiko| Miyahara, Nobuaki| Toyooka, Shinichi| Yoshino, Tadashi| Maeda, Yoshinobu| Kiura, Katsuyuki| |
キーワード | IgG4-related disease Pleural effusion Adenosine deaminase Pleural biopsy Spontaneous remission |
発行日 | 2019 |
出版物タイトル | Respiratory Medicine Case Reports |
巻 | 28巻 |
出版者 | Elsevier |
開始ページ | 100938 |
ISSN | 2213-0071 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2019 The Authors. |
論文のバージョン | publisher |
PubMed ID | 31667074 |
DOI | 10.1016/j.rmcr.2019.100938 |
Web of Science KeyUT | 000511444900052 |
関連URL | isVersionOf https://doi.org/10.1016/j.rmcr.2019.100938 |
フルテキストURL | fulltext.pdf |
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著者 | Itano, Junko| Ohashi, Kadoaki| Senoo, Satoru| Oda, Naohiro| Nishii, Kazuya| Taniguchi, Akihiko| Miyahara, Nobuaki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
キーワード | Axillary lymphadenitis Mycobacterium avium complex infection Mycobacterium intracellulare |
発行日 | 2019 |
出版物タイトル | Respiratory Medicine Case Reports |
巻 | 28巻 |
出版者 | Elsevier |
開始ページ | 100947 |
ISSN | 2213-0071 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2019 The Authors. |
論文のバージョン | publisher |
PubMed ID | 31681532 |
DOI | 10.1016/j.rmcr.2019.100947 |
Web of Science KeyUT | 000511444900001 |
関連URL | isVersionOf https://doi.org/10.1016/j.rmcr.2019.100947 |
JaLCDOI | 10.18926/AMO/57958 |
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フルテキストURL | 74_1_83.pdf |
著者 | Sakurai, Toru| Watanabe, Toshiyuki| Manako, Kensuke| Komagoe, Syo| Mukai, Yuko| Kimata, Yoshiro| Namba, Yuzaburo| |
抄録 | Nosaka, NobuyukiMastectomy is usually the first and most important surgical procedure in female-to-male (FTM) individuals with gender identity disorder. Nipple reduction is also important in the process of reconstructing the chest wall for a more male appearance. If the nipples remain large after a mastectomy, the results may be disappointing to many FTM transsexuals. Nipple reduction enables these individuals to go to the beach or Japanese public baths, where they may go topless in public. We therefore consider that nipple reduction is indicated for all FTM transsexuals who desire it. There are a variety of methods for the reduction of enlarged nipples for women or non-FTM patients, but only a few reports have described the process used to create masculine-appearing nipples for FTM transsexuals. We developed a novel technique called the Eryngii method for creating male-like nipples using a 4-mm diameter dermal punch knife. The name of the method refers to the Eryngii king trumpet mushroom, which the nipple resembles after the surgical process. The main strength of this method is that it permits the creation of ideal nipples without difficulty. Here we introduce the technique and discuss our history of surgical methods for nipple reduction, including improvements and elaborations. |
キーワード | nipple reconstruction female-to-male transmen mastectomy top surgery |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-02 |
巻 | 74巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 83 |
終了ページ | 87 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32099254 |
Web of Science KeyUT | 000516606200013 |
NAID | 120006795625 |
JaLCDOI | 10.18926/AMO/57957 |
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フルテキストURL | 74_1_77.pdf |
著者 | Endo, Hirosuke| Akazawa, Hirofumi| Yashiro, Masato| Yamada, Kazuki| Sanki, Tomoaki| Tetsunaga, Tomonori| Nishida, Keiichiro| Furumatsu, Takayuki| Ozaki, Toshifumi| |
抄録 | Idiopathic chondrolysis of the hip (ICH), a very rare disorder of unknown etiology, occurs mainly in female adolescents. Characterized by pain, limp, stiffness and radiological narrowing joint space from the rapid destruction of the articular cartilage, ICH sometimes results in ankyloses. We present the case of a 10-year-old girl diagnosed with ICH based on arthroscopic inspection and synovium biopsy. The femoral deformity appeared gradually, like a cam-type femoroacetabular impingement. She was treated with intensive rehabilitation and immunosuppressive drug. We later performed an arthroscopic bumpectomy for residual symptoms. She achieved a favorable outcome as a 15-year-old at the latest follow-up. |
キーワード | idiopathic chondrolysis hip joint medication bump arthroscopy |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-02 |
巻 | 74巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 77 |
終了ページ | 81 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32099253 |
Web of Science KeyUT | 000516606200012 |
NAID | 120006795624 |
JaLCDOI | 10.18926/AMO/57956 |
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フルテキストURL | 74_1_73.pdf |
著者 | Yamane, Masaomi| Mandai, Yasuhiro| Ino, Hideo| Matsukawa, Akihiro| Toyooka, Shinichi| |
抄録 | In 2016, Gunma University Hospital’s Medical Accident Investigation Committee released a report reiterating the necessity of medical education and the need for surgeons to master non-technical skills. We designed a 17-h training course for surgical instructors, designed to teach participants how to sufficiently educate surgeon trainees and encourage their professional identity formation. A post-training survey showed that participants improved their awareness, and their behavioral changes led to favorable team performances. We then began offering a 3-h workshop focusing on the participants’ experiences. We propose that the training course using participant narratives is required and effective to establish surgeons’ self-reflection and professional identity as surgeons. |
キーワード | professional identity instructor training narrative |
Amo Type | Short Communication |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-02 |
巻 | 74巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 73 |
終了ページ | 76 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32099252 |
Web of Science KeyUT | 000516606200011 |
NAID | 120006795623 |
JaLCDOI | 10.18926/AMO/57946 |
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フルテキストURL | 74_1_1.pdf |
著者 | Chen, Yuehua| Ohara, Toshiaki| Xing, Boyi| Qi, Jiping| Noma, Kazuhiro| Matsukawa, Akihiro| |
抄録 | Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings. |
キーワード | cancer stem cell stemness iron chelation chemotherapy |
Amo Type | Review |
出版物タイトル | Acta Medica Okayama |
発行日 | 2020-02 |
巻 | 74巻 |
号 | 1号 |
出版者 | Okayama University Medical School |
開始ページ | 1 |
終了ページ | 6 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 32099242 |
Web of Science KeyUT | 000516606200001 |
NAID | 120006795613 |
フルテキストURL | fulltext.pdf |
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著者 | Saito, Taichi| Noda, Tomoyuki| Kondo, Hiroya| Demiya, Koji| Nezu, Satoshi| Yokoo, Suguru| Matsuhashi, Minami| Uehara, Takenori| Shimamura, Yasunori| Kodama, Masayuki| Ozaki, Toshifumi| |
キーワード | Hand Induced membrane Masquelet technique Septic arthritis The small joint |
発行日 | 2020-02-29 |
出版物タイトル | Trauma Case Reports |
巻 | 25巻 |
開始ページ | 100268 |
ISSN | 23526440 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2019 The Authors. Published by Elsevier Ltd. |
論文のバージョン | publisher |
PubMed ID | 1890833 |
DOI | 10.1016/j.tcr.2019.100268 |
関連URL | isVersionOf https://doi.org/10.1016/j.tcr.2019.100268 |
フルテキストURL | fulltext.pdf |
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著者 | Eto, Eriko| Maki, Jota| Akagi, Teiji| Ito, Hiroshi| Masuyama, Hisashi| |
キーワード | Anticoagulant Fontan circulation Labor analgesia Obstetrical complications Pregnancy |
発行日 | 2019-12-30 |
出版物タイトル | Journal of Cardiology Cases |
巻 | 21巻 |
号 | 4号 |
出版者 | Elsevier |
開始ページ | 161 |
終了ページ | 163 |
ISSN | 18785409 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2019 Published by Elsevier Ltd on behalf of Japanese College of Cardiology. |
論文のバージョン | publisher |
PubMed ID | 32256867 |
DOI | 10.1016/j.jccase.2019.12.005 |
関連URL | isVersionOf https://doi.org/10.1016/j.jccase.2019.12.005 |