検索結果 1152 件
| タイトル（別表記） | A prospective cohort study to define the clinical and pathological features of lung cancers harboring HER2 gene aberrations (the HER2-CS Study) and a phase II study of trastuzumab emtansine (recombinant) in patients with HER2-positive non-small cell lung cancer who recurred, progressed after standard chemotherapy, or were primarily refractory to standard chemotherapy |
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| フルテキストURL | 127_127.pdf |
| 著者 | 木浦 勝行| 堀田 勝幸| 佐藤 晃子| 大橋 圭明| 二宮 崇| 南 大輔| 田端 雅弘| 久保 寿夫| 加藤 有加| 平田 泰三| |
| キーワード | 臨床研究中核病院 国立研究開発法人日本医療研究開発機構 文部科学省橋渡し研究加速ネットワークプログラム HER2-CS study trastuzumab emtansine |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-08-03 |
| 巻 | 127巻 |
| 号 | 2号 |
| 開始ページ | 127 |
| 終了ページ | 132 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.127.127 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.127 |
| NAID | 130005096256 |
| タイトル（別表記） | Successful laparoscopic resection of a cecal tumor in a 95-year-old man |
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| フルテキストURL | 127_117.pdf |
| 著者 | 渡邉 彩子| 稲田 涼| 永坂 岳司| 八木 朝彦| 松本 聖| 戸嶋 俊明| 菊池 覚次| 黒田 新士| 近藤 喜太| 母里 淑子| 岸本 浩行| 藤原 俊義| |
| 抄録 | We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients. |
| キーワード | 超高齢者（extremely elderly patient） 大腸癌（colorectal cancer） 腹腔鏡手術（laparoscopic surgery） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-08-03 |
| 巻 | 127巻 |
| 号 | 2号 |
| 開始ページ | 117 |
| 終了ページ | 121 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.127.117 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.117 |
| NAID | 130005096253 |
| 著者 | 伊藤 麻里子| 稲垣 秀晃| 森 ララミ| 戸田 真弓| 青野 修一| 佐藤 純| |
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| 発行日 | 2015-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 31巻 |
| 資料タイプ | その他 |
| タイトル（別表記） | Okayama University Survey of the current situation of community-based medical facilities supported by part-time work by physicians |
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| フルテキストURL | 127_13.pdf |
| 著者 | 勅使川 早苗| 岩瀬 敏秀| 金森 達也| 川畑 智子| 佐藤 勝| 片岡 仁美| |
| 抄録 | We investigated the situation of how physicians at Okayama University support local medical institutions by serving as a part-time worker, and analyzed the difference between the five medical districts of Okayama prefecture and other prefectures. Many physicians (actual number of physicians, full-time equivalent number of physicians) served in the southeastern region of the Okayama prefecture (339, 82.2). On the other hand, fewer physicians (42, 11.4) served in Takahashi・Niimi in the northwestern region of Okayama. Many physicians also served in Hiroshima prefecture (193, 48.8), Hyogo prefecture (109, 26.7), and the four prefectures of Shikoku Island (81, 23.6). It has been clarified that many physicians at Okayama University are working on a part-time basis to support local and community medical institutions in the wide area of Okayama prefecture, Hiroshima prefecture, Hyogo prefecture and the four prefectures of Shikoku Island. |
| キーワード | 岡山大学勤務医師（physicians at Okayama University） 非常勤勤務（part-time worker） 地域医療機関支援（community-based medical facilities） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-04-01 |
| 巻 | 127巻 |
| 号 | 1号 |
| 開始ページ | 13 |
| 終了ページ | 17 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.13 |
| NAID | 130005068345 |
| タイトル（別表記） | A Note on Structuring the Health-care and Nursing Care Delivery System in Regional Areas |
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| フルテキストURL | olj_064_3_4_626_617.pdf |
| 著者 | 佐藤 吾郎| |
| 出版物タイトル | 岡山大學法學會雜誌 |
| 発行日 | 2015-03-19 |
| 巻 | 64巻 |
| 号 | 3・4号 |
| 開始ページ | 626 |
| 終了ページ | 617 |
| ISSN | 0386-3050 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005567878 |
| JaLCDOI | 10.18926/AMO/53027 |
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| フルテキストURL | 68_6_375.pdf |
| 著者 | Yamanaka, Reiko| Soga, Yoshihiko| Moriya, Yoshie| Okui, Akemi| Takeuchi, Tetsuo| Sato, Kenji| Morimatsu, Hiroshi| Morita, Manabu| |
| 抄録 | We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care. |
| キーワード | mouth protector tongue laceration |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-12 |
| 巻 | 68巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 375 |
| 終了ページ | 378 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25519032 |
| Web of Science KeyUT | 000346882200008 |
| JaLCDOI | 10.18926/AMO/53023 |
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| フルテキストURL | 68_6_339.pdf |
| 著者 | Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi| |
| 抄録 | The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ｧ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care. |
| キーワード | advance healthcare directive living will end-of-life care palliative care unit place of death |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-12 |
| 巻 | 68巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 339 |
| 終了ページ | 348 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25519028 |
| Web of Science KeyUT | 000346882200004 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53134 |
| JaLCDOI | 10.18926/AMO/53021 |
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| フルテキストURL | 68_6_323.pdf |
| 著者 | Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito| |
| 抄録 | In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV. |
| キーワード | HFOV mean lung pressure mean airway pressure |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-12 |
| 巻 | 68巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 323 |
| 終了ページ | 329 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25519026 |
| Web of Science KeyUT | 000346882200002 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53132 |
| 著者 | Tomotsuka, Naoto| Kaku, Ryuji| Obata, Norihiko| Matsuoka, Yoshikazu| Kanzaki, Hirotaka| Taniguchi, Arata| Muto, Noriko| Omiya, Hiroki| Itano, Yoshitaro| Sato, Tadasu| Ichikawa, Hiroyuki| Mizobuchi, Satoshi| Morimatsu, Hiroshi| |
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| 発行日 | 2014-07-11 |
| 出版物タイトル | Journal of Pain Research |
| 巻 | 7巻 |
| 資料タイプ | 学術雑誌論文 |
| フルテキストURL | K0005044_abstract_review.pdf K0005044_fulltext.pdf |
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| 著者 | 佐藤 将也| |
| 発行日 | 2014-09-30 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5044号 |
| 学位授与年月日 | 2014-09-30 |
| 学位・専攻分野 | 博士（工学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| 著者 | Zou, Yu| Wang, Da-Hong| Sakano, Noriko| Sato, Yoshie| Iwanaga, Suketaka| Taketa, Kazuhisa| Kubo, Masayuki| Takemoto, Kei| Masatomi, Chie| Inoue, Kiyomi| Ogino, Keiki| |
|---|---|
| 発行日 | 2014-02 |
| 出版物タイトル | International Journal of Environmental Research and Public Health |
| 巻 | 11巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Iwatani, Kayoko| Takata, Katsuyoshi| Sato, Yasuharu| Miyata-Takata, Tomoko| Iwaki, Noriko| Cui, Wei| Sawada-Kitamura, Seiko| Sonobe, Hiroshi| Tamura, Maiko| Saito, Katsuhiko| Miyatani, Katsuya| Yamasaki, Rie| Yamadori, Ichiro| Fujii, Nobuharu| Terasaki, Yasushi| Maeda, Yoshinobu| Tanimoto, Mitsune| Nakamura, Naoya| Yoshino, Tadashi| |
|---|---|
| 発行日 | 2014-07 |
| 出版物タイトル | Human Pathology |
| 巻 | 45巻 |
| 号 | 7号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Sato, Kota| Morimoto, Nobutoshi| Kurata, Tomoko| Mimoto, Takafumi| Miyazaki, Kazunori| Ikeda, Yoshio| Abe, Koji| |
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| 発行日 | 2012-09-14 |
| 出版物タイトル | Brain Research |
| 巻 | 1473巻 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/52788 |
|---|---|
| フルテキストURL | 68_4_219.pdf |
| 著者 | Hinamoto, Norikazu| Maeshima, Yohei| Saito, Daisuke| Yamasaki, Hiroko| Tanabe, Katsuyuki| Nasu, Tatsuyo| Watatani, Hiroyuki| Ujike, Haruyo| Kinomura, Masaru| Sugiyama, Hitoshi| Sonoda, Hikaru| Kanomata, Naoki| Sato, Yasufumi| Makino, Hirofumi| |
| 抄録 | Experimental studies have demonstrated the involvement of angiogenesis-related factors in the progression of chronic kidney disease (CKD). There have so far been no reports investigating the distribution and clinical roles of Vasohibin-1 (VASH-1), a negative feedback regulator of angiogenesis, in CKD. We recruited 54 Japanese CKD patients and 6 patients who had normal renal tissues excised due to localized renal cell carcinoma. We evaluated the correlations between the renal expression level of VASH-1 and the clinical/histological parameters. VASH-1 was observed in renal endothelial/mesangial cells, crescentic lesions and interstitial inflammatory cells. Significant positive correlations were observed between 1) crescent formation and the number of VASH-1+ cells in the glomerulus (r＝0.48, p＝0.001) or cortex (r＝0.64, p＜0.0001), 2) interstitial cell infiltration and the number of VASH-1+ cells in the cortex (r＝0.34, p＝0.02), 3) the glomerular VEGFR-2+ area and the number of VASH-1+ cells in the glomerulus (r＝0.44, p＝0.01) or medulla (r＝0.63, p＝0.01). These results suggest that the renal levels of VASH-1 may be affected by local inflammation, crescentic lesions and VEGFR-2. |
| キーワード | chronic kidney disease inflammation Vasohibin-1 VEGF-A VEGFR-2 |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-08 |
| 巻 | 68巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 219 |
| 終了ページ | 233 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25145408 |
| Web of Science KeyUT | 000340687500004 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52824 |
| JaLCDOI | 10.18926/OLR/52746 |
|---|---|
| タイトル（別表記） | On the training and continuing legal education for in-house lawyers in regional areas－The idea of Okayama University Attorney Training Center（OATC）－ |
| フルテキストURL | olr_013_001_014.pdf |
| 著者 | 佐藤 吾郎| |
| 出版物タイトル | 臨床法務研究 |
| 発行日 | 2014-07 |
| 巻 | 13巻 |
| 開始ページ | 1 |
| 終了ページ | 14 |
| ISSN | 1881-1485 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005464788 |
| タイトル（別表記） | Induction therapy followed by surgery for non small-cell lung cancer |
|---|---|
| フルテキストURL | 126_103.pdf |
| 著者 | 豊岡 伸一| |
| キーワード | 非小細胞肺癌 導入療法 放射線化学療法 外科切除 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 103 |
| 終了ページ | 107 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.103 |
| NAID | 130004685260 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize) |
|---|---|
| フルテキストURL | 126_83.pdf |
| 著者 | 村田 等| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 83 |
| 終了ページ | 86 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.83 |
| NAID | 130004685272 |
| JaLCDOI | 10.18926/AMO/52652 |
|---|---|
| フルテキストURL | 68_3_129.pdf |
| 著者 | Minoura, Akira| Wang, Da-Hong| Sato, Yoshie| Zou, Yu| Sakano, Noriko| Kubo, Masayuki| Takemoto, Kei| Masatomi, Chie| Ogino, Keiki| |
| 抄録 | We examined the relationships between dietary carbohydrate, protein, fat, and the ratio of n6/n3 fatty acid intakes with the predicted 10-year coronary heart disease (CHD) risk in a general Japanese population. We used the Framingham risk score to determine the 10-year CHD risk of the subjects, who were employees of 6 companies in a single prefecture in Japan. After excluding the subjects who reported any history of angina pectoris, myocardial infarction, diabetes, or cancer, and those with missing data resulting in the inability of estimation of 10-year CHD risk and food intakes, the final data analysis was carried out for 809 subjects. The logistic regression models revealed a significantly increased odds ratio of 10-year CHD risk in the subjects with the highest tertile of carbohydrate intake (% energy) (odds ratio 3.64, 95% CI, 2.07-6.40);after adjustment for other variables, the odds ratio for the 10-year CHD risk was also higher in the subjects with the highest tertile of carbohydrate intake (odds ratio 1.72, 95% CI, 0.70-4.25). We also found that fat intake and the ratio of n6/n3 fatty acids were inversely associated with the predicted 10-year CHD risk (p for trend＜0.01). The present findings added evidence of a positive association of dietary carbohydrate and inverse associations of total fat and n6/n3 fatty acid ratio with the predicted 10-year CHD risk in a general Japanese population. |
| キーワード | fat intake carbohydrate intake ratio of n6/n3 fatty acids 10-year coronary heart disease risk Japanese |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 129 |
| 終了ページ | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942790 |
| Web of Science KeyUT | 000337655600001 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52516 |
| フルテキストURL | K0004908_abstract_review.pdf K0004908_fulltext.pdf |
|---|---|
| 著者 | 佐藤 恒太| |
| 発行日 | 2014-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第4908号 |
| 学位授与年月日 | 2014-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 英語 |
| 著者 | 佐藤 勝紀| |
|---|---|
| 発行日 | 2014-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 30巻 |
| 資料タイプ | その他 |