検索結果 1116 件
| フルテキストURL | GGI_17_11_1991.pdf |
|---|---|
| 著者 | Fukui, Yusuke| Hishikawa, Nozomi| Ichinose, Jin| Sato, Kota| Nakano, Yumiko| Morihara, Ryuta| Ohta, Yasuyuki| Yamashita, Toru| Abe, Koji| |
| キーワード | Alzheimer's disease antidementia drug magnetic resonance imaging periventricular hyperintensity white matter lesions |
| 備考 | This is an Accepted Manuscript of an article published by Wiley| This fulltext will be available in Nov 2018| |
| 発行日 | 2017-11 |
| 出版物タイトル | Geriatrics & Gerontology International |
| 巻 | 17巻 |
| 号 | 11号 |
| 出版者 | Japan Geriatrics Society |
| 開始ページ | 1991 |
| 終了ページ | 1999 |
| ISSN | 1444-1586 |
| NCID | AA1155729X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | author |
| PubMed ID | 28276131 |
| DOI | 10.1111/ggi.13007 |
| Web of Science KeyUT | 000416330000029 |
| 関連URL | isVersionOf https://doi.org/10.1111/ggi.13007 |
| タイトル（別表記） | Two cases of solid-pseudopapillary neoplasm of the pancreas with contrasting imaging findings |
|---|---|
| フルテキストURL | 129_171.pdf |
| 著者 | 河合 毅| 遠藤 芳克| 渡邉 貴紀| 甲斐 恭平| 佐藤 四三| |
| 抄録 | A solid pseudo-papillary tumor of the pancreas is a rare neoplasm which mainly occurs in young women. Here, we report two cases of solid-pseudopapillary neoplasm of the pancreas (SPN) with contrasting imaging findings. One was a 59-year-old woman having no symptomatic complaint with a pancreatic cystic tumor in the tail. The tumor was 60 mm in diameter with a cyst composed of a calcified wall and low-density content which was poorly perfused on contrast-enhanced computed tomography (CT). We diagnosed SPN based on imaging findings and performed distal pancreatectomy. Histology revealed SPN, and the patient had two years of recurrence -free survival (RFS). The other case was a 34-year-old man with an asymptomatic solid tumor in the pancreatic tail. Contrast-enhanced CT showed low peripheral attenuation of a 25-mm solid tumor, with the main duct dilated distal from tumor. We diagnosed him with pancreatic cancer with atypical image findings. Pathological findings revealed SPN, and the patient had five years of RFS. Small-sized SPN is being increasingly recognized because of the recent advances in CT and MRI. We should consider SPN even if it occurs in a male, and endoscopic ultrasound -guided fine-needle aspiration has recently been reported to be useful in diagnosing SPN. |
| キーワード | 膵SPN（solid-pseudopapillary neoplasm of the pancreas） EUS-FNA（endoscopic ultrasound-guided fine needle aspiration） 成人男性（male） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-12-01 |
| 巻 | 129巻 |
| 号 | 3号 |
| 開始ページ | 171 |
| 終了ページ | 177 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.129.171 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.171 |
| NAID | 40021393857 |
| JaLCDOI | 10.18926/AMO/55591 |
|---|---|
| フルテキストURL | 71_6_531.pdf |
| 著者 | Ooi, Mayu| Yanamoto, Fujio| Sato, Hitoaki| Takao, Yumiko| Okada, Masako| Egi, Moritoki| Mizobuchi, Satoshi| |
| 抄録 | Although spinal cord stimulation (SCS) is a useful treatment for chronic intractable pain, the optimal method of stimulation has not yet been established. In this prospective, crossover study, we compared the efficacy of using a constant current (CC) system with that of a constant voltage (CV) system for temporal SCS. Twenty patients were enrolled and divided into two groups. For 10 patients, a CV system was applied on Days 1-5, followed by the use of a CC system on Days 6-10. For the other 10 patients, a CC system was applied for the first five days, followed by a CV system for the subsequent five days. We evaluated the alteration of pain intensity using a visual analogue scale (VAS), the area of stimulation, the stability of effect, and patient satisfaction regarding treatment. The pain scores decreased significantly after the start of the SCS. There was no significant difference in the change in VAS between the two systems. The stimulation method used for temporal SCS did not affect the reduction of pain intensity. Patients felt a wider stimulation area by the CC system compared to the CV system. |
| キーワード | spinal cord stimulation constant current system constant voltage system chronic intractable pain pain score |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-12 |
| 巻 | 71巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 531 |
| 終了ページ | 537 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29276227 |
| フルテキストURL | K0005600_other1.pdf |
|---|---|
| 著者 | Takeda, Tatsuaki| Yamamoto, Hiromasa| Kanzaki, Hirotaka| Suzawa, Ken| Yoshioka, Takahiro| Tomida, Shuta| Cui, Xiaojiang| Murali, Ramachandran| Namba, Kei| Sato, Hiroki| Torigoe, Hidejiro| Watanabe, Mototsugu| Shien, Kazuhiko| Soh, Junichi| Asano, Hiroaki| Tsukuda, Kazunori| Kitamura, Yoshihisa| Miyoshi, Shinichiro| Sendo, Toshiaki| Toyooka, Shinichi| |
| 備考 | 学位審査副論文| |
| 発行日 | 2017-02-03 |
| 出版物タイトル | PLoS One |
| 巻 | 12巻 |
| 号 | 2号 |
| 出版者 | Public Library of Science |
| 開始ページ | e0171356 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | publisher |
| PubMed ID | 28158234 |
| DOI | 10.1371/journal.pone.0171356 |
| Web of Science KeyUT | 000396161700064 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0171356 isPartOf http://ousar.lib.okayama-u.ac.jp/55525 |
| フルテキストURL | K0005592_other1.pdf |
|---|---|
| 著者 | Hinamoto, Norikazu| Maeshima, Yohei| Yamasaki, Hiroko| Nasu, Tatsuyo| Saito, Daisuke| Watatani, Hiroyuki| Ujike, Haruyo| Tanabe, Katsuyuki| Masuda, Kana| Arata, Yuka| Sugiyama, Hitoshi| Sato, Yasufumi| Makino, Hirofumi| |
| 備考 | 学位審査副論文| |
| 発行日 | 2014-09-25 |
| 出版物タイトル | Plos One |
| 巻 | 9巻 |
| 号 | 9号 |
| 出版者 | Public Library of Science |
| 開始ページ | e107934 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 論文のバージョン | publisher |
| PubMed ID | 25255225 |
| DOI | 10.1371/journal.pone.0107934 |
| Web of Science KeyUT | 000344862300045 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0107934 isPartOf http://ousar.lib.okayama-u.ac.jp/55517 |
| フルテキストURL | K0005600_abstract_review.pdf K0005600_summary.pdf K0005600_fulltext.pdf |
|---|---|
| 著者 | 佐藤 博紀| |
| 発行日 | 2017-09-29 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5600号 |
| 学位授与年月日 | 2017-09-29 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/55442 |
|---|---|
| フルテキストURL | 71_5_433.pdf |
| 著者 | Yukimasa, Nobuyasu| Kohama, Shota| Oboshi, Wataru| Sato, Shoichi| Nakamura, Takehiro| |
| 抄録 | We investigated the genetic mechanisms underlying the association between human leukocyte antigen (HLA) types and the immune response to hepatitis B virus (HBV) vaccination in 84 healthy Japanese adults, and found that the HLA-DRB1＊04 and HLA-DQB1＊03 frequencies were higher in the low responders (<10 mIU/ml; n=9, 10.7%) compared to the responders (≥10 mIU/ml, n=75, 89.3%). The combination of DRB1＊04 and DQB1＊03 was associated with a low response to vaccination. The DRB1＊04 and DQB1＊03 haplotypes’ frequencies were significantly higher in the low responders compared to responders. Novel candidate HLA types may be important in Japanese individuals. |
| キーワード | HBV vaccine antibody response low-responder HLA class II Japanese |
| Amo Type | Short Communication |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-10 |
| 巻 | 71巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 433 |
| 終了ページ | 436 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29042702 |
| JaLCDOI | 10.18926/AMO/55438 |
|---|---|
| フルテキストURL | 71_5_407.pdf |
| 著者 | Marukawa, Yohei| Sato, Shuhei| Tanaka, Takashi| Tada, Akihiro| Kanie, Yuichiro| Kanazawa, Susumu| |
| 抄録 | We retrospectively evaluated the qualities of pediatric cardiovascular dual-source computed tomography (DSCT) images reconstructed by sinogram-affirmed iterative reconstruction (SAFIRE) and filtered back projection (FBP). We analyzed the cases of 287 congenital heart disease (CHD) patients < 5 years old, referred to our department in August 2013-March 2015. We divided them into two groups according to tube voltage (70 kVp, n=147; 80 kVp, n=140). All images were acquired by a CARE kV system and reconstructed by FBP and SAFIRE. The attenuation, noise, and signal-to-noise ratio (SNR) at each region of the heart and great vessels were measured. The volume CT dose index and dose-length product values were recorded. Compared to FBP, reconstruction by SAFIRE showed that the attenuation volume was significantly lower by 0.4% except for the ascending aorta (p<0.05), the noise value was lower by about 20% (p<0.05), and the SNR was higher by approx. 25% (p<0.05). The radiation dose in the 70 kVp group was significantly lower than that in the 80 kVp group. No significant differences in SNR were observed between the patient groups. DSCT image acquisition with SAFIRE using the CARE kV system results in low image noise and radiation dose in pediatric patients with CHD. |
| キーワード | congenital heart disease iterative reconstruction low-kV computed tomography pediatric |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-10 |
| 巻 | 71巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 407 |
| 終了ページ | 412 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29042698 |
| JaLCDOI | 10.18926/AMO/55434 |
|---|---|
| フルテキストURL | 71_5_369.pdf |
| 著者 | Arata, Yuka| Tanabe, Katsuyuki| Hinamoto, Norikazu| Yamasaki, Hiroko| Sugiyama, Hitoshi| Maeshima, Yohei| Kanomata, Naoki| Sato, Yasufumi| Wada, Jun| |
| 抄録 | Several angiogenesis-related factors are known to play important roles in the pathogenesis of kidney disease. Vasohibin-2 (VASH-2) was recently reported as a novel proangiogenic factor. Although VASH-2 was demonstrated to accelerate tumor angiogenesis, its roles in non-tumor processes including renal disease have not been well elucidated yet. Here, we performed a retrospective study including an immunohistochemical analysis of human kidney biopsy specimens from 82 Japanese patients with a variety of kidney diseases, and we evaluated the correlations between the immunoreactivity of VASH-2 and the patients’ clinicopathological parameters. VASH-2 immunoreactivity was detected in varying degrees in renal tubules as well as in peritubular capillaries and vasa recta. The cortical and medullary tubule VASH-2+ scores were correlated with the presence of hypertension, and the medullary tubule VASH-2+ score was significantly correlated with the blood glucose (p=0.029, r=0.35) and hemoglobin A1c levels (p=0.0066, r=0.39). Moreover, decreased VASH-2+ scores in the vasa recta were associated with reduced renal function (p=0.0003). These results suggest that VASH-2 could play an important role in the pathogenesis of renal diseases, and that VASH-2 is closely associated with hypertension and impaired glucose tolerance. |
| キーワード | vasohibin-2 kidney disease vasa recta medullary tubules |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-10 |
| 巻 | 71巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 369 |
| 終了ページ | 380 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29042694 |
| フルテキストURL | K0005304 other1.pdf |
|---|---|
| 著者 | Igawa, Takuro| Sato, Yasuharu| Takata, Katsuyoshi| Iwaki, Noriko| Tanaka, Takehiro| Asano, Naoko| Maeda, Yoshinobu| Orita, Yorihisa| Nakamura, Naoya| Nakamura, Shigeo| Yoshino, Tadashi| |
| キーワード | Cyclin D2 CD5 Diffuse large B-cell lymphoma |
| 備考 | 学位審査副論文| |
| 発行日 | 2013-05-15 |
| 出版物タイトル | Diagnostic Pathology |
| 巻 | 8巻 |
| 出版者 | BioMed Central |
| 開始ページ | 81 |
| ISSN | 1746-1596 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | publisher |
| PubMed ID | 23675804 |
| DOI | 10.1186/1746-1596-8-81 |
| Web of Science KeyUT | 000319266300002 |
| 関連URL | https://doi.org/10.1186/1746-1596-8-81 http://ousar.lib.okayama-u.ac.jp/54287 |
| JaLCDOI | 10.18926/AMO/55305 |
|---|---|
| フルテキストURL | 71_4_291.pdf |
| 著者 | Naganuma, Atsushi| Hoshino, Takashi| Suzuki, Yuhei| Uehara, Daisuke| Kudo, Tomohiro| Ishihara, Hiroshi| Sato, Ken| Kakizaki, Satoru| Yamada, Masanobu| Takagi, Hitoshi| |
| 抄録 | The effect of skeletal muscle mass (SMM) on the outcomes of sorafenib treatment for hepatocellular carcinoma (HCC) has not been established. We measured the SMM in HCC patients treated with sorafenib, evaluated the patients’ survival, and evaluated the association between skeletal muscle depletion and sorafenib treatment. Of the 97 HCC patients treated with sorafenib at our institution in the period from July 2009 to February 2015, our study included 69 patients (51 males, 18 females) who had received sorafenib for ≥ 8 weeks and whose follow-up data were available. SMM was calculated from computed tomography images at the mid-L3 level (cm2) and normalized to height (m2) to yield the L3 skeletal muscle index (L3-SMI, cm2/m2). The median L3-SMI value was higher in the males (43 cm2/m2) compared to the females (36 cm2/m2). In the males only, the multivariate Cox regression identified an L3-SMI <43 cm2/m2 as independently associated with higher mortality compared to an L3-SMI ≥43 cm2/m2 (hazard ratio 2.315, 95% confidence interval: 1.125-4.765, p=0.023). Skeletal muscle depletion is a factor predicting poor prognosis for male patients with advanced HCC treated with sorafenib. |
| キーワード | skeletal muscle depletion hepatocellular carcinoma sorafenib L3 skeletal muscle index prognostic factor |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-08 |
| 巻 | 71巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 291 |
| 終了ページ | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28824184 |
| フルテキストURL | PlantCellRep_36_4_611.pdf PlantCellRep_36_4_611_supl.pdf Supplemental_tables.xlsx |
|---|---|
| 著者 | Hisano, Hiroshi| Meints, Brigid| Moscou, Matthew J.| Cistue, Luis| Echávarri, Begoña| Sato, Kazuhiro| Hayes, Patrick M.| |
| キーワード | Agrobacterium tumefaciens Doubled haploid Hordeum vulgare (barley) Single nucleotide polymorphism Transformation |
| 発行日 | 2017-04 |
| 出版物タイトル | Plant Cell Reports |
| 巻 | 36巻 |
| 号 | 4号 |
| 出版者 | Springer |
| 開始ページ | 611 |
| 終了ページ | 620 |
| ISSN | 0721-7714 |
| NCID | AA10635864 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | author |
| PubMed ID | 28204911 |
| DOI | 10.1007/s00299-017-2107-2 |
| Web of Science KeyUT | 000398735600009 |
| 関連URL | isVersionOf https://doi.org/10.1007/s00299-017-2107-2 |
| タイトル（別表記） | Achalasia treated with per-oral endoscopic myotomy (POEM) |
|---|---|
| フルテキストURL | 129_115.pdf |
| 著者 | 杉原 雄策| 原田 馨太| 加藤 諒| 山内 健司| 高嶋 志保| 竹井 大介| 井口 俊博| 高原 政宏| 川野 誠司| 平岡 佐規子| 田辺 俊介| 野間 和宏| 白川 靖博| 眞部 紀明| 井上 晴洋| 岡田 裕之| |
| 抄録 | Esophageal achalasia is a disorder of the lower esophageal sphincter muscle. Patients present with dysphagia, chest pain, vomiting, and aspiration. Esophageal achalasia had traditionally been treated with esophageal achalasia balloon dilatation and the Heller-Dor method, but in recent years, the use of per-oral endoscopic myotomy (POEM) has increased. Our patient, a 39-yr-old male, began experiencing dysphagia 4 years prior to his referral to our hospital. Based on the results of esophagogastroduodenoscopy, esophageal radiography and high-resolution manometry, we made the diagnosis of esophageal achalasia (Chicago classification type I) . After informed consent from the patient and his family and approval from our hospital's ethics committee were obtained, we performed a POEM. The patient was discharged on the 4th day post-surgery. At the 1-year post-operative examination, no worsening of symptoms and no relapse were observed. POEM is an excellent treatment method for esophageal achalasia from the perspective of therapeutic effect and prevention of invasion. We recommend that it be considered as the first-choice treatment for achalasia. However, accessibility to the procedure itself is limited due to the few adequately trained operators worldwide. POEM should thus be performed by an expert operator at a high-volume center. |
| キーワード | POEM 食道アカラシア (esophageal achalasia) |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-08-01 |
| 巻 | 129巻 |
| 号 | 2号 |
| 開始ページ | 115 |
| 終了ページ | 121 |
| ISSN | 0030-1558 |
| 関連URL | https://doi.org/10.4044/joma.129.115 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.115 |
| NAID | 130006039377 |
| フルテキストURL | K0005280_fulltext.pdf |
|---|---|
| 著者 | Ishigami, Shuta| Ohtsuki, Shinichi| Tarui, Suguru| Ousaka, Daiki| Eitoku, Takahiro| Kondo, Maiko| Okuyama, Michihiro| Kobayashi, Junko| Baba, Kenji| Arai, Sadahiko| Kawabata, Takuya| Yoshizumi, Ko| Tateishi, Atsushi| Kuroko, Yosuke| Iwasaki, Tatsuo| Sato, Shuhei| Kasahara, Shingo| Sano, Shunji| Oh, Hidemasa| |
| キーワード | cell therapy congenital heart disease hypoplastic left heart syndrome stem cells |
| 備考 | 学位審査副論文| |
| 発行日 | 2015-02 |
| 出版物タイトル | Circulation Research |
| 巻 | 116巻 |
| 号 | 4号 |
| 出版者 | Lippincott Williams & Wilkins |
| 開始ページ | 653 |
| 終了ページ | 664 |
| ISSN | 00097330 |
| NCID | AA00133553 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | author |
| PubMed ID | 25403163 |
| DOI | 10.1161/circresaha.116.304671 |
| Web of Science KeyUT | 000349804900015 |
| 関連URL | https://doi.org/10.1161/CIRCRESAHA.116.304671 http://ousar.lib.okayama-u.ac.jp/54044 http://ousar.lib.okayama-u.ac.jp/54263 |
| フルテキストURL | K0005542_abstract_review.pdf K0005542_fulltext.pdf |
|---|---|
| 著者 | 佐藤 慧太| |
| 発行日 | 2017-03-24 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5542号 |
| 学位授与年月日 | 2017-03-24 |
| 学位・専攻分野 | 博士（理学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | K0005519_abstract_review.pdf.pdf K0005519_filltext.pdf.pdf |
|---|---|
| 著者 | 佐藤 寛和| |
| 発行日 | 2017-03-24 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5519号 |
| 学位授与年月日 | 2017-03-24 |
| 学位・専攻分野 | 博士（法学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| フルテキストURL | K0005474_abstract_review.pdf K0005474_summary.pdf K0005474_fulltext.pdf |
|---|---|
| 著者 | 佐藤 卓也| |
| 発行日 | 2017-03-24 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5474号 |
| 学位授与年月日 | 2017-03-24 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/54978 |
|---|---|
| フルテキストURL | 71_2_105.pdf |
| 著者 | Shinya, Takayoshi| Tanaka, Takashi| Soh, Junichi| Matsushita, Toshi| Sato, Shuhei| Toyooka, Shinichi| Yoshino, Tadashi| Miyoshi, Shinichiro| Kanazawa, Susumu| |
| 抄録 | We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy. |
| キーワード | thymic epithelial neoplasm thymic carcinoma thymoma dual-time-point PET/CT chest CT |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 105 |
| 終了ページ | 112 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420891 |
| JaLCDOI | 10.18926/AMO/54976 |
|---|---|
| フルテキストURL | 71_2_91.pdf |
| 著者 | Ogawa, Nanako| Sato, Shuhei| Ida, Kentaro| Kato, Katsuya| Ariyoshi, Yuichi| Wada, Koichiro| Nasu, Yasutomo| Kanazawa, Susumu| |
| 抄録 | The aim of this study was to investigate the utility of single-source dual-energy computed tomography (SS-DECT) composition analysis in characterizing different types of urinary stones and differentiating them from phleboliths. This study included 29 patients with urinary stones who were scheduled for surgery. All patients were scanned, first using single-energy computed tomography acquisition and then DECT acquisition on SS-DECT. Dual-energy data were archived to a Gemstone spectral imaging (GSI) viewer (GE Healthcare, Milwaukee, WI, USA). Hounsfield units (HU) and effective atomic numbers (Zeff) were estimated using the GSI viewer. The results of dual-energy analysis were compared with the biochemical constitution of the stones. The chemical analysis determined that the stones included 32 calcium-based, 6 cystine and 1 struvite stone. Both HU and Zeff values were helpful in differentiating calcium-based stones from cystine and struvite stones and phleboliths. The Zeff values of phleboliths were significantly higher than those for struvite and cystine stones, whereas it was difficult to distinguish phleboliths from struvite and cystine stones using the HU values. Composition analysis using SS-DECT is helpful for distinguishing urinary stone types and discriminating phleboliths from urinary stones. Zeff values may be more useful than HU values for differentiating urinary stones from phleboliths. |
| キーワード | single-source dual-energy computed tomography effective atomic number urinary stone phlebolith |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 91 |
| 終了ページ | 96 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420889 |
| JaLCDOI | 10.18926/54966 |
|---|---|
| タイトル（別表記） | Birth of the United Nations Partition Resolution on Palestine and Loss of the Unitary State Plan : Focusing on the Discussion in the Ad Hoc Committee |
| フルテキストURL | hss_043_081_099.pdf |
| 著者 | 佐藤 寛和| |
| 出版物タイトル | 岡山大学大学院社会文化科学研究科紀要 |
| 発行日 | 2017-03-24 |
| 巻 | 43巻 |
| 開始ページ | 81 |
| 終了ページ | 100 |
| ISSN | 1881-1671 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山大学大学院社会文化科学研究科 |
| 論文のバージョン | publisher |
| NAID | 120006026987 |