検索結果 - 岡山大学学術成果リポジトリ

平成25年度岡山医学会賞がん研究奨励賞（林原賞・山田賞）

タイトル（別表記）	The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize)
フルテキストURL	126_191.pdf
著者	枝園和彦\|
抄録	受賞対象論文: Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S：Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res (2013) 73, 3051-3061.
出版物タイトル	岡山医学会雑誌
発行日	2014-12-01
巻	126巻
号	3号
開始ページ	191
終了ページ	194
ISSN	0030-1558
言語	日本語
著作権者	Copyright (c) 2014 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.126.191
NAID	130004903236

平成25年度岡山医学会賞総合研究奨励賞（結城賞）

タイトル（別表記）	The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize)
フルテキストURL	126_187.pdf
著者	山本寛斉\|
抄録	受賞対象論文: Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S：Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas. J Natl Cancer Inst (2014) 106, djt338
出版物タイトル	岡山医学会雑誌
発行日	2014-12-01
巻	126巻
号	3号
開始ページ	187
終了ページ	190
ISSN	0030-1558
言語	日本語
著作権者	Copyright (c) 2014 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.126.187
NAID	130004903235

Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy

著者	Oshima, Masamitsu\| Inoue, Kaoru\| Nakajima, Kei\| Tachikawa, Tetsuhiko\| Yamazaki, Hiromichi\| Isobe, Tomohide\| Sugawara, Ayaka\| Ogawa, Miho\| Tanaka, Chie\| Saito, Masahiro\| Kasugai, Shohei\| Takano-Yamamoto, Teruko\| Inoue, Takashi\| Tezuka, Katsunari\| Kuboki, Takuo\| Yamaguchi, Akira\| Tsuji, Takashi\|
発行日	2014-08-13
出版物タイトル	Scientific Reports
巻	4巻
資料タイプ	学術雑誌論文

単語の共起や頻度に注目した注意要因及び類似事例の抽出

著者	箕輪弘嗣\| 宗澤良臣\| 鈴木和彦\|
発行日	2012-10-15
出版物タイトル	安全工学
巻	51巻
号	5号
資料タイプ	学術雑誌論文

Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide

著者	Mori, Izumi C.\| Arias-Barreiro, Carlos R.\| Koutsaftis, Apostolos\| Ogo, Atsushi\| Kawano, Tomonori\| Yoshizuka, Kazuharu\| Inayat-Hussain, Salmaan H.\| Aoyama, Isao\|
発行日	2015-02
出版物タイトル	Chemosphere
巻	120巻
資料タイプ	学術雑誌論文

Seed Maturation Regulators Are Related to the Control of Seed Dormancy in Wheat (Triticum aestivum L.)

著者	Rikiishi, Kazuhide\| Maekawa, Masahiko\|
発行日	2014-09-11
出版物タイトル	PLoS ONE
巻	9巻
号	9号
資料タイプ	学術雑誌論文

HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse

著者	Ichiyanagi, Tomoko\| Ichiyanagi, Kenji\| Ogawa, Ayako\| Kuramochi-Miyagawa, Satomi\| Nakano, Toru\| Chuma, Shinichiro\| Sasaki, Hiroyuki\| Udono, Heiichiro\|
発行日	2014-09-27
出版物タイトル	Nucleic Acids Research
巻	42巻
号	19号
資料タイプ	学術雑誌論文

Identification of a mammalian vesicular polyamine transporter

著者	Hiasa, Miki\| Miyaji, Takaaki\| Haruna, Yuka\| Takeuchi, Tomoya\| Harada, Yuika\| Moriyama, Sawako\| Yamamoto, Akitsugu\| Omote, Hiroshi\| Moriyama, Yoshinori\|
発行日	2014-10-30
出版物タイトル	Scientific Reports
巻	4巻
資料タイプ	学術雑誌論文

Spinal Metaplastic Meningioma with Osseous Differentiation in the Ventral Thoracic Spinal Canal

JaLCDOI	10.18926/AMO/52901
フルテキストURL	68_5_313.pdf
著者	Yamane, Kentaro\| Tanaka, Masato\| Sugimoto, Yoshihisa\| Ichimura, Kouichi\| Ozaki, Toshifumi\|
抄録	Ossified meningioma is classified histologically as a phenotype of metaplastic meningioma, and it is extremely rare. There are only 12 cases involving ossified spinal meningiomas in the literature. We present the case of a 61-year-old female with a primary tumor within the ventral spinal canal at T12. Although we performed a total tumor excision using an ultrasonic bone aspirator, a temporary deterioration of motor evoked potentials (MEPs) was observed during curettage with a Kerrison rongeur. The neurologic findings worsened immediately after surgery. Histologically, the tumor was diagnosed as a metaplastic meningioma with osseous differentiation. In order to avoid spinal cord injury, great care must be taken when removing an ossified meningioma located on the ventral spinal cord.
キーワード	spinal metaplastic meningioma osseous differentiation ossified meningioma ultrasonic bone aspirator post-operative course
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2014-10
巻	68巻
号	5号
出版者	Okayama University Medical School
開始ページ	313
終了ページ	316
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25338489
Web of Science KeyUT	000343269300009

Prompt Resolution of Hypoglycemia by Hepatic Transarterial Embolization for Malignant Insulinoma with Multiple Liver Metastases

JaLCDOI	10.18926/AMO/52900
フルテキストURL	68_5_307.pdf
著者	Muro, Shinichiro\| Nasu, Junichiro\| Harada, Ryo\| Matsubara, Minoru\| Nakarai, Asuka\| Kanzaki, Hiromitsu\| Tsutsumi, Kouichiro\| Kato, Hironari\| Tanaka, Takehiro\| Fujiwara, Hiroyasu\| Uno, Masatoshi\| Okada, Hiroyuki\| Yamamoto, Kazuhide\|
抄録	A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia.
キーワード	malignant insulinoma hypoglycemia liver metastases transarterial embolization neuroendocrinetumor
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2014-10
巻	68巻
号	5号
出版者	Okayama University Medical School
開始ページ	307
終了ページ	311
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25338488
Web of Science KeyUT	000343269300008

A Rare Course of Scoliosis Associated with Chiari Malformation and Syringomyelia

JaLCDOI	10.18926/AMO/52899
フルテキストURL	68_5_303.pdf
著者	Tanaka, Masato\| Sugimoto, Yoshihisa\| Arataki, Shinya\| Takigawa, Tomoyuki\| Ozaki, Toshifumi\|
抄録	Spinal deformity is an important clinical manifestation of Chiari I malformation (CM-I) and syringomyelia. Here we report the result of an 8-year follow-up of a 13-year-old girl with severe scoliosis associated with Chiari malformation and a large syringomyelia. The patient presented at our hospital at the age of 13 with a 68° scoliosis. Magnetic resonance imaging showed Chiari malformation and a large syringomyelia. Neurosurgical treatment involved foramen magnum decompression and partial C1 laminectomy, but the scoliosis still progressed. We present the first case report of a rare course of scoliosis in a patient with CM-I and a large syringomyelia.
キーワード	Chiari I malformation syringomyelia scoliosis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2014-10
巻	68巻
号	5号
出版者	Okayama University Medical School
開始ページ	303
終了ページ	306
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25338487
Web of Science KeyUT	000343269300007

A New Classification System for Evaluating Patients with Severe Trauma Using B-type Natriuretic Peptide Levels and Estimated Glomerular Filtration Rate

JaLCDOI	10.18926/AMO/52897
フルテキストURL	68_5_285.pdf
著者	Morisada, Sunao\| Ugawa, Toyomu\| Nosaka, Nobuyuki\| Ujike, Yoshihito\|
抄録	Current systems for the evaluation of trauma severity are tedious and difficult to apply in an actual emergency setting. We aimed to develop and assess the accuracy of a more efficient severity evaluation system, termed the Ugawa classification, using brain-type natriuretic peptide (BNP) measurement and the estimated glomerular filtration rate (eGFR). Two-hundred trauma patients were divided into 2 groups using an eGFR cut-off value of 90ml/min/1.73m2 as an indicator of normal renal function and 2 additional groups according to whether the BNP values were greater or less than the age in years. This resulted in 4 subject groups with different combinations of eGFR and BNP. The mean SOFA score, injury severity scores (ISS), trauma and injury severity scores (TRISS), and Acute Physiology and Chronic Health Evaluation II (APACHE II) scores of the groups were compared by Kruskal-Wallis test, and the mortality rate after 90 days was calculated. Significant intergroup differences were found in SOFA scores, ISS scores, and APACHE II-predicted mortality rates. Although no significant differences were found in the mortality rate after 90 days or TRISS-predicted mortality rate among the 4 groups, there was a trend toward increasing trauma severity from group 1 to 4. Thus, the Ugawa classification is as accurate as existing systems, has greater efficiency, and is user-friendly.
キーワード	acute injury Acute Physiology and Chronic Health Evaluation II injury severity score sequential organ failure assessment trauma and injury severity score
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2014-10
巻	68巻
号	5号
出版者	Okayama University Medical School
開始ページ	285
終了ページ	290
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25338485
Web of Science KeyUT	000343269300005
関連URL	http://ousar.lib.okayama-u.ac.jp/metadata/52958

Three-dimensional Assessment of Femoral Head Coverage in Normal and Dysplastic Hips: A Novel Method

JaLCDOI	10.18926/AMO/52896
フルテキストURL	68_5_277.pdf
著者	Miyasaka, Dai\| Ito, Tomoyuki\| Imai, Norio\| Suda, Ken\| Minato, Izumi\| Dohmae, Yoichiro\| Endo, Naoto\|
抄録	The acetabular coverage of the femoral head has been assessed in two-dimensions as the projected covered area or the covered angle on plain radiographs. We present a novel method of the three-dimensional assessment of femoral head coverage obtained by evaluating the covered volume of the femoral head in both normal and dysplastic hips. We also assessed the covered angles on the vertical slices passing through the center of the femoral head. The mean covered volume of the femoral head was 57.4% in normal hips and 26.6% in dysplastic hips. In dysplastic hips, the L-CE, A-CE, and P-CE angles were 7.7°, 21.8°, and 95.8°, respectively, while the acetabular angle was 27.5°. In normal hips, the CE angles were 34.0°, 56.8°, and 109.4°, respectively, while the acetabular angle was 7.2°. Our study suggests the usefulness of a novel 3D assessment for acetabular coverage of the femoral head. This assessment provided the precise 3D information necessary to diagnose hip dysplasia and assess the deficiency of acetabular coverage in these patients. Moreover, we may detect a cut-off between normal and dysplastic hips in the 3D assessment by assessing a large number of dysplastic hips both morphologically and using the new assessment.
キーワード	hip dysplasia three-dimensional imaging femoral head coverage acetabulum patient positioning
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2014-10
巻	68巻
号	5号
出版者	Okayama University Medical School
開始ページ	277
終了ページ	284
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25338484
Web of Science KeyUT	000343269300004

Chronic Orofacial Pain in Dental Patients: Retrospective Investigation over 12 years

JaLCDOI	10.18926/AMO/52895
フルテキストURL	68_5_269.pdf
著者	Tomoyasu, Yumiko\| Higuchi, Hitoshi\| Mori, Megumi\| Takaya, Kumiko\| Honda, Yuka\| Yamane, Ayaka\| Yabuki, Akiko\| Hayashi, Tomoko\| Ishii-Maruhama, Minako\| Jinzenji, Ayako\| Maeda, Shigeru\| Kohjitani, Atsushi\| Shimada, Masahiko\| Miyawaki, Takuya\|
抄録	Orofacial pain is often difficult to diagnose and treat. However, there have been few reports on the clinical observation of dental patients with orofacial pain. We retrospectively investigated the characteristics of 221 dental patients who had suffered from persistent orofacial pain. Data were collected from the outpatient medical records in our clinic over the past 12 years. More than half of the patients (53.8%) had suffered with pain for more than 6 months from pain onset until the first visit to our clinic. The main diagnoses were neuropathic pain (30.3%), myofascial pain (23.5%), psychogenic pain (20.4%), odontogenic toothache (17.2%), and others (7.7%) such as temporomandibular disorders and glossitis. The treatments included pharmacotherapy, splint therapy, and others such as nerve block, dental treatment, physiotherapy, and/or psychotherapy. Excluding the patients (52 of 221 initially enrolled patients) with unknown responses to treatment, 65.7% showed remission or a significant improvement in pain in response to treatment. Although only a small group of patients had odontogenic toothache, the rate of improvement was highest for this disorder. In conclusion, early consultation with a dentist is useful to prevent chronicity of odontogenic pain and to make a differential diagnosis in patients with orofacial pain.
キーワード	dental patients pain clinic orofacial pain dental anesthesiology clinical observation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2014-10
巻	68巻
号	5号
出版者	Okayama University Medical School
開始ページ	269
終了ページ	275
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25338483
Web of Science KeyUT	000343269300003

安全教育のため手の甲によるバルブ速度測定画像認識法

著者	箕輪弘嗣\| 宗澤良臣\| 橋本康平\|
発行日	2014-10-15
出版物タイトル	安全工学
巻	53巻
号	5号
資料タイプ	学術雑誌論文

Assessment of intraoral mucosal pain induced by the application of capsaicin

著者	Terayama, Ryuji\| Maruhama, Kotaro\| Tsuchiya, Hiroki\| Mizutani, Masahide\| Iida, Seiji\| Sugimoto, Tomosada\|
発行日	2014-12
出版物タイトル	Archives of Oral Biology
巻	59巻
号	12号
資料タイプ	学術雑誌論文

Efficient Drug Delivery of Paclitaxel Glycoside: A Novel Solubility Gradient Encapsulation into Liposomes Coupled with Immunoliposomes Preparation

フルテキストURL	PLOSONE_9_9_e107976.pdf
著者	Shigehiro, Tsukasa\| Kasai, Tomonari\| Murakami, Masaharu\| Sekhar, Sreeja C.\| Tominaga, Yuki\| Okada, Masashi\| Kudoh, Takayuki\| Mizutani, Akifumi\| Murakami, Hiroshi\| Salomon, David S.\| Mikuni, Katsuhiko\| Mandai, Tadakatsu\| Hamada, Hiroki\| Seno, Masaharu\|
発行日	2014-09-29
出版物タイトル	PLoS ONE
巻	9巻
号	9号
出版者	Public Library Science
開始ページ	e107976
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	publisher
PubMed ID	25264848
DOI	10.1371/journal.pone.0107976
Web of Science KeyUT	000345745400036
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0107976

First Synthesis of Asperopterin A, an Isoxanthopterin Glycoside from Aspergillus Oryzae

著者	Hanaya, Tadashi\| Yamamoto, Hiroshi\|
発行日	2013-06
出版物タイトル	Pteridines
巻	24巻
号	1号
資料タイプ	学術雑誌論文

Effect of repeated Waon therapy on exercise tolerance and pulmonary function in patients with chronic obstructive pulmonary disease: a pilot controlled clinical trial

著者	Kikuchi, Hiroshi\| Shiozawa, Nobuyoshi\| Takata, Shingo\| Ashida, Kozo\| Mitsunobu, Fumihiro\|
発行日	2013-12-12
出版物タイトル	International Journal of Chronic Obstructive Pulmonary Disease
巻	9巻
資料タイプ	学術雑誌論文

Maintenance of glucose-sensitive insulin secretion of cryopreserved human islets with University of Wisconsin solution and ascorbic acid-2 glucoside

著者	Arata, T\| Okitsu, T\| Fukazawa, T\| Ikeda, H\| Kobayashi, K\| Yong, C\| Kosaka, Y\| Narushima, M\| Matsuoka, J\| Yamamoto, I\| Tanaka, N\| Lakey, JRT\| Kobayashi, N\|
発行日	2004-06
出版物タイトル	Artificial Organs
巻	28巻
号	6号
資料タイプ	学術雑誌論文