検索条件

閉じる

検索結果 18783 件

JaLCDOI 10.18926/AMO/59954
フルテキストURL 74_3_221.pdf
著者 Yagura, Takuma| Oe, Kenichi| Paku, Masaaki| Tajima, Takeshi| Nakamura, Masaya| Iida, Hirokazu| Saito, Takanori|
抄録 We retrospectively evaluated the cases of 169 hip fracture patients, their previous fractures, and the contralateral hip joint’s morphology. A history of contralateral hip fracture was present in 23 patients (Contra group). The other patients had a unilateral hip fracture: a trochanteric fracture (Troch group, n=73) or a femoral neck fracture (Neck group, n=73). In the Troch and Neck groups, we used anteroposterior and cross-table axialview radiographs of the contralateral hip to evaluate the proximal femur’s anatomy. In the Contra group, the concordance rate between the first and second types of hip fracture was 65.2%, and the second hip fracture’s morphology indicated that the trochanteric fracture had a cam deformity in terms of the femoral head-neck ratio. The average alpha angle and femoral head-neck offset in the Troch group were significantly larger than those in the Neck group. In the Neck group, pistol-grip deformities of Arbeitsgemeinschaft für Osteosynthesefragen types B1 (subcapital), B2 (transcervical), and B3 (displaced) were observed in 42.1%, 75%, and 6% of cases, respectively. There was a smaller alpha angle and a larger femoral head-neck offset in the contralateral hip of femoral neck fractures; thus, the “cam deformity” may protect against femoral neck fractures.
キーワード cam deformity femoral neck fracture trochanteric fracture bilateral hip fractures
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 221
終了ページ 227
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577020
Web of Science KeyUT 000543363400006
NAID 120006862796
フルテキストURL fulltext.pdf
著者 Hiranaka, Takaaki| Furumatsu, Takayuki| Tanaka, Takaaki| Okazaki, Yuki| Kodama, Yuya| Kamatsuki, Yusuke| Masuda, Kenji| Seno, Noritaka| Ozaki, Toshifumi|
キーワード anterior cruciate ligament knee pullout suture screw fixation tibial eminence avulsion fracture
発行日 2020-06-03
出版物タイトル Journal of Orthopaedic Surgery
28巻
2号
出版者 SAGE Publications
開始ページ 2309499020918681
ISSN 2309-4990
NCID AA11004541
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020
論文のバージョン publisher
PubMed ID 32489139
DOI 10.1177/2309499020918681
Web of Science KeyUT 000539749100001
関連URL isVersionOf https://doi.org/10.1177/2309499020918681
JaLCDOI 10.18926/AMO/59952
フルテキストURL 74_3_215.pdf
著者 Chou, Hsi-Hsien|
抄録 Due to cultural traditions, most Taiwanese do not have an advance directive or healthcare proxy. We explored how patients with mild dementia in Taiwan may still make self-determined decisions concerning advance directives for their healthcare and end-of-life care choices as the disease progresses. We examined 260 respondents with mild dementia at a Taiwan medical center: 199 patients who agreed (and 61 patients who disagreed) with the concept of advance directives completed a structured questionnaire. Multiple logistic regression models to determine the between-group differences revealed that the following were positively associated with approval of end-of-life directives: maintaining one’s quality of life (adjusted odds ratio [AOR], 2.44; 95% CI: 1.07-5.53), discussion with family members (AOR, 3.50; 95% CI: 1.49-8.26), and friend support networks (AOR, 3.36; 95% CI: 1.34-8.43). Cardiopulmonary resuscitation (AOR, 0.27; 95% CI: 0.09-0.79) was negatively associated with approval. There was also a positive association between the support of the legal validity of end-of-life directives (OR, 1.93; 95% CI: 1.07-3.48), without other confounding factors. In Taiwanese society, we remain mindful of cultural influences that may impact patients, including maintaining one’s quality of life, discussion with family members, and friend/support networks. These influences may help dementia patients complete their advance directives.
キーワード advance directive dementia patient autonomy quality of life culture
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 215
終了ページ 220
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577019
Web of Science KeyUT 000543363400005
NAID 120006862794
JaLCDOI 10.18926/AMO/59951
フルテキストURL 74_3_209.pdf
著者 Matsui, Yusuke| Hiraki, Takao| Iguchi, Toshihiro| Sakurai, Jun| Uka, Mayu| Masaoka, Yoshihisa| Gobara, Hideo| Kanazawa, Susumu|
抄録 An aspiration-type semi-automatic cutting biopsy needle enables tissue cutting during application of negative pressure, which is expected to contribute to a larger amount of specimen. The aim of the present study was to evaluate this novel needle in a clinical setting. Patients who underwent image-guided percutaneous biopsy for lung or renal masses were enrolled. Cutting biopsy was performed with and without aspiration during each procedure. The specimens were weighed using an electronic scale. The weights were compared between specimens obtained with and without aspiration using a paired t-test. The data from 45 lung and 30 renal biopsy procedures were analyzed. In lung biopsy, the mean±standard deviation weights of specimens obtained with and without aspiration were 2.20±1.05 mg and 2.24±1.08 mg, respectively. In renal biopsy, the mean weights were 6.52±2.18 mg and 6.42±1.62 mg, respectively. The weights were not significantly different between specimens obtained with and without aspiration either in lung (p=0.799) or renal (p=0.789) biopsies. The application of negative pressure with the aspiration-type semi-automatic cutting biopsy needle did not contribute to an increase in the amount of the specimen obtained in lung and renal biopsies.
キーワード biopsy cutting needle aspiration clinical study
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 209
終了ページ 214
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577018
Web of Science KeyUT 000543363400004
NAID 120006862793
JaLCDOI 10.18926/AMO/59950
フルテキストURL 74_3_199.pdf
著者 Fujita, Hirofumi| Bando, Tetsuya| Oyadomari, Seiichi| Ochiai, Kazuhiko| Watanabe, Masami| Kumon, Hiromi| Ohuchi, Hideyo|
抄録 Dickkopf 3 (Dkk3) is a secreted protein belonging to the Dkk family and encoded by the orthologous gene of REIC. Dkk3/REIC is expressed by mouse and human adrenal glands, but the understanding of its roles in this organ is still limited. To determine the functions of Dkk3 in the mouse adrenal gland, we first identified that the mouse Dkk3 protein is N-glycosylated in the adrenal gland as well as in the brain. We performed proteome analysis on adrenal glands from Dkk3-null mice, in which exons 5 and 6 of the Dkk3 gene are deleted. Twodimensional polyacrylamide gel electrophoresis of adrenal proteins from wild-type and Dkk3-null mice revealed 5 protein spots whose intensities were altered between the 2 genotypes. Mass spectrometry analysis of these spots identified binding immunoglobulin protein (BiP), an endoplasmic reticulum (ER) chaperone. To determine whether mouse Dkk3 is involved in the unfolded protein response (UPR), we carried out a reporter assay using ER-stress responsive elements. Forced expression of Dkk3 resulted in the induction of distinct levels of reporter expression, showing the UPR initiated by the ER membrane proteins of activating transcription factor 6 (ATF6) and inositol-requring enzyme 1 (IRE1). Thus, it is possible that Dkk3 is a physiological ER stressor in the mouse adrenal gland.
キーワード Dkk3 knockout mouse adrenal gland glucose-regulated protein 78 proteome endoplasmic reticulum stress
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 199
終了ページ 208
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577017
Web of Science KeyUT 000543363400003
NAID 120006862792
JaLCDOI 10.18926/AMO/59949
フルテキストURL 74_3_191.pdf
著者 Ohashi, Keiji| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Asano, Sumie Hiramatsu| Miyawaki, Yoshia| Morishita, Michiko| Katsuyama, Eri| Watanabe, Haruki| Tatebe, Noriko| Narazaki, Mariko| Matsumoto, Yoshinori| Sunahori-Watanabe, Katsue| Kawabata, Tomoko| Yajima, Nobuyuki| Wada, Jun|
抄録 Chronic damage accumulation affects not only mortality but also quality of life in patients with systemic lupus erythematosus (SLE). Risk factors for chronic damage were explored in SLE through different onset eras. Two hundred forty-five patients at Okayama University Hospital and Showa University Hospital were divided into three groups based on the onset era: a past-onset group (onset before 1995; n=83), middle-onset group (1996-2009; n=88), and recent-onset group (after 2010; n=74). The mean Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) score as an index of chronic damage was 1.93, 1.24, and 0.53 in the past-, middle-, and recent-onset groups, respectively. In the pastonset group, the total SDI score was significantly associated with glucocorticoid monotherapy by linear regression analysis (β-coefficient [β]=0.63; 95% confidence interval [CI], 0.21-1.05) and C-reactive protein levels (β=0.67; 95% CI, 0.27-1.07). In the middle-onset group, the total SDI score was significantly associated with the SLE Disease Activity Index at registration (β=0.09; 95% CI, 0.03-0.12). Reducing the accumulation of chronic damage in SLE patients might be possible with the concomitant use of immunosuppressants and tight control of disease activity.
キーワード systemic lupus erythematosus chronic damage glucocorticoids, disease activity disease duration
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 191
終了ページ 198
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577016
Web of Science KeyUT 000543363400002
NAID 120006862791
JaLCDOI 10.18926/AMO/59948
フルテキストURL 74_3_185.pdf
著者 Sano, Toshikazu| Ishigami, Shuta| Ito, Tatsuo| Sano, Shunji|
抄録 Heart diseases are one of the major causes of morbidity and mortality worldwide. Despite major advances in drug and interventional therapies, surgical procedures, and organ transplantation, further research into new therapeutic options is still necessary. Stem cell therapy has emerged as one option for the treatment of a variety of heart diseases. Although a large number of clinical trials have shown stem cell therapy to be a promising therapeutic approach, the results obtained from these clinical studies are inconsistent, and stem cell-based improvements of heart performance and cardiac remodeling were found to be quite limited. Since the precise mechanisms underlying the therapeutic actions of stem cells are still under debate, researchers have developed a variety of strategies to improve and boost the potency of stem cells in repair. In this review, we summarize both the current therapeutic strategies using stem cells and future directions for enhancing stem cell potency.
キーワード heart disease stem cell myocardial regeneration
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2020-06
74巻
3号
出版者 Okayama University Medical School
開始ページ 185
終了ページ 190
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32577015
Web of Science KeyUT 000543363400001
NAID 120006862790
フルテキストURL fulltext.pdf Tables.pdf Figures.pdf
著者 Hirata, Seiji| Hayashi, Saori| Ohta, Masamitsu|
キーワード Three sections of wood Glossiness Color measurement L*a*b* color space L*C*h color space Density Average of annual ring width
備考 This is a post-peer-review, pre-copyedit version of an article published in Journal of Wood Science. The final authenticated version is available online at: https://doi.org/10.1186/s10086-020-01883-2.|
発行日 2020-05-19
出版物タイトル Journal of Wood Science
66巻
出版者 Springer
ISSN 1435-0211
NCID AA11200007
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
DOI 10.1186/s10086-020-01883-2
Web of Science KeyUT 000533783500001
関連URL isVersionOf https://doi.org/10.1186/s10086-020-01883-2
フルテキストURL Biomaterials_251_fulltext.pdf Biomaterials_251_supplementarydata.pdf
著者 Tanaka, Hiroyoshi Y.| Kurihara, Tsuyoshi| Nakazawa, Takuya| Matsusaki, Michiya| Masamune, Atsushi| Kano, Mitsunobu R.|
キーワード 3D culture Cancer-associated fibroblast Pancreatic stellate cell Tumor stroma Pancreatic cancer Myofibroblast
備考 ©2021 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.biomaterials.2020.120077] . |
発行日 2020-04-30
出版物タイトル Biomaterials
251巻
出版者 Elsevier
開始ページ 120077
ISSN 0142-9612
NCID AA00110092
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 32388166
DOI 10.1016/j.biomaterials.2020.120077
Web of Science KeyUT 000534057500006
関連URL isVersionOf https://doi.org/10.1016/j.biomaterials.2020.120077
フルテキストURL Biomaterials_192_fulltext.pdf Biomaterials_192_supplementarydata.pdf
著者 Tanaka, Hiroyoshi Y.| Kitahara, Kentaro| Sasaki, Naoki| Nakao, Natsumi| Sato, Kae| Narita, Hirokazu| Shimoda, Hiroshi| Matsusaki, Michiya| Nishihara, Hiroshi| Atsushi Masamune| Kano, Mitsunobu R.|
キーワード Fibrosis Extracellular matrix remodeling 3D culture Pancreatic stellate cell SPARC
発行日 2018-11-17
出版物タイトル Biomaterials
192巻
出版者 Elsevier
開始ページ 355
終了ページ 367
ISSN 0142-9612
NCID AA00110092
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 30476717
DOI 10.1016/j.biomaterials.2018.11.023
Web of Science KeyUT 000456902000029
関連URL isVersionOf https://doi.org/10.1016/j.biomaterials.2018.11.023
フルテキストURL JCR_230_fulltext.pdf
著者 Sakai, Satoshi| Iwata, Caname| Tanaka, Hiroyoshi Y.| Cabral, Horacio| Morishita, Yasuyuki| Miyazon, Kohei| Kano, Mitsunobu R.|
キーワード Macromolecular drugs Drug distribution Pancreatic ductal adenocarcinoma Fibrosis FGF-2
発行日 2016-05-28
出版物タイトル Journal of Controlled Release
230巻
出版者 Elsevier
開始ページ 109
終了ページ 115
ISSN 0168-3659
NCID AA10458678
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 27080571
DOI 10.1016/j.jconrel.2016.04.007
Web of Science KeyUT 000375412500012
関連URL isVersionOf https://doi.org/10.1016/j.jconrel.2016.04.007
フルテキストURL fulltext.pdf
著者 Hoshijima, Mitsuhiro| Hattori, Takako| Aoyama, Eriko| Nishida, Takashi| Kubota, Satoshi| Kamioka, Hiroshi| Takigawa, Masaharu|
キーワード cellular communication network factor 2 CCN2 CTGF Rab14 yeast two-hybrid chondrocyte ER stress aggrecan
発行日 2020-04-16
出版物タイトル International Journal of Molecular Sciences
21巻
8号
出版者 MDPI
ISSN 1422-0067
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 32316324
DOI 10.3390/ijms21082769
Web of Science KeyUT 000535565300111
関連URL isVersionOf https://doi.org/10.3390/ijms21082769
フルテキストURL fulltext.pdf
著者 Ogawa-Akiyama, Ayu| Sugiyama, Hitoshi| Kitagawa, Masashi| Tanaka, Keiko| Kano, Yuzuki| Mise, Koki| Otaka, Nozomu| Tanabe, Katsuyuki| Morinaga, Hiroshi| Kinomura, Masaru| Uchida, Haruhito A.| Wada, Jun|
発行日 2020-01-24
出版物タイトル PLoS ONE
15巻
1号
出版者 Public Library of Science
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 Ogawa-Akiyama et al.
論文のバージョン publisher
PubMed ID 31978139
DOI 10.1371/journal.pone.0228337
Web of Science KeyUT 000534599100142
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0228337
フルテキストURL fulltext.pdf
著者 Tsunashima, Kenta| Jinno, Katsuya| Hiramatsu, Bunta| Fujimoto, Kayo| Sakai, Kenji| Kiwa, Toshihiko| Saari, Mohd Mawardi| Tsukada, Keiji|
発行日 2020-01
出版物タイトル AIP Advances
10巻
1号
出版者 AIP Publishing
ISSN 2158-3226
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Author(s) 2020
論文のバージョン publisher
DOI 10.1063/1.5130167
Web of Science KeyUT 000525829300017
関連URL isVersionOf https://doi.org/10.1063/1.5130167
フルテキストURL fulltext.pdf
著者 Matsuoka, Natsumi| Tsuji, Kenji| Ichihara, Eiki| Hara, Takayuki| Fukushima, Kazuhiko| Toma, Kishio| Kitamura, Shinji| Inagaki, Kenichi| Sugiyama, Hitoshi| Wada, Jun|
キーワード Pembrolizumab Hypothyroidism Creatinine Cystatin C
発行日 2020-03-31
出版物タイトル BMC Nephrology
21巻
出版者 BMC
開始ページ 113
ISSN 1471-2369
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s). 2020
論文のバージョン publisher
PubMed ID 32234009
DOI 10.1186/s12882-020-01775-z
Web of Science KeyUT 000522961400004
関連URL isVersionOf https://doi.org/10.1186/s12882-020-01775-z
フルテキストURL fulltext.pdf
著者 Tazawa, Hiroshi| Hasei, Joe| Yano, Shuya| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi|
キーワード oncolytic adenovirus hTERT autophagy GFP p53
発行日 2020-02-18
出版物タイトル Cancers
12巻
2号
出版者 MDPI
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 32085583
DOI 10.3390/cancers12020478
Web of Science KeyUT 000522477300224
関連URL isVersionOf https://doi.org/10.3390/cancers12020478
フルテキストURL fulltext.pdf
著者 Taniguchi-Tabata, Ayano| Takeuchi, Noriko| Uchida, Yoko| Ekuni, Daisuke| Morita, Manabu|
キーワード Periodontitis Risk factors
発行日 2020-01-29
出版物タイトル Scientific Reports
10巻
出版者 Nature Research
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020
論文のバージョン publisher
PubMed ID 31996751
DOI 10.1038/s41598-020-58396-7
Web of Science KeyUT 000528914700004
関連URL isVersionOf https://doi.org/10.1038/s41598-020-58396-7
フルテキストURL fulltext.pdf
著者 Nakayama, Rie| Takaya, Yoichi| Akagi, Teiji| Nakagawa, Koji| Watanabe, Nobuhisa| Nobusada, Saori| Matsushita, Toshi| Toh, Norihisa| Kanazawa, Susumu| 伊藤 浩|
発行日 2020-04-28
出版物タイトル Journal of Interventional Cardiology
2020巻
出版者 Hindawi
開始ページ 9509105
ISSN 0896-4327
NCID AA10705096
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 Rie Nakayama et al.
論文のバージョン publisher
PubMed ID 32410917
DOI 10.1155/2020/9509105
Web of Science KeyUT 000533371500001
関連URL isVersionOf https://doi.org/10.1155/2020/9509105
フルテキストURL fulltext.pdf
著者 Osman, Amira| Afify, Said M.| Hassan, Ghmkin| Fu, Xiaoying| Seno, Akimasa| Seno, Masaharu|
キーワード CAFs TECs TAAs TAMs CSCs
発行日 2020-04-04
出版物タイトル Cancers
12巻
4号
出版者 MDPI
開始ページ 879
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 32260363
DOI 10.3390/cancers12040879
Web of Science KeyUT 000535587400108
関連URL isVersionOf https://doi.org/10.3390/cancers12040879
フルテキストURL fulltext.pdf
著者 Luong, Minh N.| Shimada, Yasushi| Araki, Kazuyuki| Yoshiyama, Masahiro| Tagami, Junji| Sadr, Alireza|
キーワード dentin enamel optical coherence tomography radiograph receiver operating characteristic (ROC) analysis hidden caries dentino-enamel junction DEJ
発行日 2020-03-17
出版物タイトル Sensors
20巻
6号
出版者 MDPI
開始ページ 1659
ISSN 1424-8220
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 32192069
DOI 10.3390/s20061659
Web of Science KeyUT 000529139700118
関連URL isVersionOf https://doi.org/10.3390/s20061659