検索結果 49252 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Goux, Pierre| Glessgen, Franz| Gazzola, Enrico| Reen, Mandeep Singh| Focillon, William| Gonin, Michel| Tanaka, Tomoyuki| Hagiwara, Kaito| Ali, Ajmi| Sudo, Takashi| Koshio, Yusuke| Sakuda, Makoto| Collazuol, Gianmaria| Kimura, Atsushi| Nakamura, Shoji| Iwamoto, Nobuyuki| Harada, Hideo| Wurm, Michael| |
| 発行日 | 2023-05-05 |
| 出版物タイトル | Progress of Theoretical and Experimental Physics |
| 巻 | 2023巻 |
| 号 | 6号 |
| 出版者 | Oxford University Press |
| 開始ページ | 063H01 |
| ISSN | 2050-3911 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| DOI | 10.1093/ptep/ptad059 |
| Web of Science KeyUT | 000999497600002 |
| 関連URL | isVersionOf https://doi.org/10.1093/ptep/ptad059 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Okada, Nobuhiro| Ueki, Chihiro| Shimazaki, Masahiro| Tsujimoto, Goki| Kohno, Susumu| Muranaka, Hayato| Yoshikawa, Kiyotsugu| Takahashi, Chiaki| |
| 備考 | The version of record of this article, first published in Communications Biology, is available online at Publisher’s website: http://dx.doi.org/10.1038/s42003-023-04987-9| |
| 発行日 | 2023-06-02 |
| 出版物タイトル | Communications Biology |
| 巻 | 6巻 |
| 号 | 1号 |
| 出版者 | nature portfolio |
| 開始ページ | 596 |
| ISSN | 2399-3642 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 37268670 |
| DOI | 10.1038/s42003-023-04987-9 |
| Web of Science KeyUT | 000999915600001 |
| 関連URL | isVersionOf https://doi.org/10.1038/s42003-023-04987-9 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Uchiyama, Takaki| Goto, Hidenori| Uesugi, Eri| Takai, Akihisa| Zhi, Lei| Miura, Akari| Hamao, Shino| Eguchi, Ritsuko| Ota, Hiromi| Sugimoto, Kunihisa| Fujiwara, Akihiko| Matsui, Fumihiko| Kimura, Koji| Hayashi, Kouichi| Ueno, Teppei| Kobayashi, Kaya| Akimitsu, Jun| Kubozono, Yoshihiro| |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-27701-5| |
| 発行日 | 2023-01-11 |
| 出版物タイトル | Scientific Reports |
| 巻 | 13巻 |
| 号 | 1号 |
| 出版者 | nature portfolio |
| 開始ページ | 537 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 36631625 |
| DOI | 10.1038/s41598-023-27701-5 |
| Web of Science KeyUT | 000986510100067 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-023-27701-5 |
| JaLCDOI | 10.18926/AMO/65497 |
|---|---|
| フルテキストURL | 77_3_319.pdf |
| 著者 | Kashihara, Kenichi| |
| 抄録 | I report a case of arterial spine-labelled MR imaging (ASL)-detected cerebral hypoperfusion during migraine and panic attacks. A 20-year-old woman with a history of headache for 6 years and independent panic attacks for 3 years was transferred to Okayama Kyokuto Hospital for panic attacks. On that day, she had had severe headache that was improved by taking non-steroidal anti-inflammatory drug, but panic attacks initiated. On arrival, she also complained of a mild headache. ASL revealed cerebral hypoperfusion in the right temporo-occipital region. The threshold to induce panic attacks in migraine patients could be lowered by the physiopathology underlying migraine attacks. |
| キーワード | migraine panic attack arterial spine-labelled magnetic resonance imaging aura cortical spreading depression |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 319 |
| 終了ページ | 321 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357633 |
| Web of Science KeyUT | 001026279600010 |
| JaLCDOI | 10.18926/AMO/65496 |
|---|---|
| フルテキストURL | 77_3_311.pdf |
| 著者 | Miura, Takanori| Kijima, Hiroaki| Tazawa, Hiroshi| Miyakoshi, Naohisa| |
| 抄録 | Japan’s hip fracture management guidelines now recommend the use of cemented stems in cases of bone fragility. However, the current stem selection practices in bipolar hemiarthroplasty (BHA) in a super-aging area in Japan remain unclear. This study aimed to examine the stem selection policies, the surgeons’ concerns about cemented stems, and factors affecting their confidence in their ability to coach others on cemented stem procedures. Ninety-four orthopedic surgeons (27 facilities) responded to our web-based questionnaire conducted in January/February 2022. Cementless stem was the first choice of 97.8% of the surgeons; <15% of the respondents expected to increase their use of cemented stems in the future. The cement technique was the greatest concern; almost half of the surgeons described having insufficient experience with cemented stems. The factor that most affected the surgeons’ expertise in using cemented stems is the number of surgeries they had conducted with a cemented stem (multivariable analysis odds ratio 8.42, p=0.001). Greater experience was associated with increased expertise of the surgeons in using cemented stems, with a threshold of 11 cases showing sensitivity of 41.7% and specificity of 98.3% for their confidence to instruct cemented stems. |
| キーワード | hip fracture arthroplasty bone cement questionnaire |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 311 |
| 終了ページ | 318 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357632 |
| Web of Science KeyUT | 001026279600009 |
| JaLCDOI | 10.18926/AMO/65495 |
|---|---|
| フルテキストURL | 77_3_301.pdf |
| 著者 | Kato, Takahide| Miyoshi, Seigo| Hamada, Chizuru| Sano, Yoshifumi| Nogami, Naoyuki| Yamaguchi, Osamu| Hamaguchi, Naohiko| |
| 抄録 | Acute exacerbation (AE) of interstitial lung disease (ILD) is a severe complication of lung resection in lung cancer patients with ILD (LC-ILD). This study aimed to assess the predictive value of comorbidities other than ILD for postoperative AE in patients with LC-ILD. We retrospectively evaluated 68 patients with LC-ILD who had undergone lung resection. We classified them into two groups: those who had developed postoperative AE within 30 days after resection and those who had not. We analyzed patient characteristics, high-resolution computed tomography findings, clinical data, pulmonary function, and intraoperative data. The incidence of postoperative AEs was 11.8%. In univariate analysis, performance status (PS), honeycombing, forced vital capacity (FVC), and high hemoglobin A1c (HbA1c) levels without comorbidities were significantly associated with postoperative AE. Patients were divided into two groups according to cutoff levels of those four variables as determined by receiver operating characteristic curves, revealing that the rates of patients without postoperative AE differed significantly between groups. The present results suggested that preoperative comorbidities other than ILD were not risk factors for postoperative AE in patients with LC-ILD. However, a high preoperative HbA1c level, poor PS, low FVC, and honeycombing may be associated with postoperative AE of LC-ILD. |
| キーワード | lung cancer interstitial lung disease acute exacerbation comorbidity |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 301 |
| 終了ページ | 309 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357631 |
| Web of Science KeyUT | 001026279600008 |
| JaLCDOI | 10.18926/AMO/65494 |
|---|---|
| フルテキストURL | 77_3_291.pdf |
| 著者 | Himei, Hitomi| Kato, Hironari| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| 抄録 | We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal. |
| キーワード | benign biliary stricture inside stent plastic stent |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 291 |
| 終了ページ | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357630 |
| Web of Science KeyUT | 001026279600007 |
| JaLCDOI | 10.18926/AMO/65493 |
|---|---|
| フルテキストURL | 77_3_281.pdf |
| 著者 | Mukai, Yuko| Taira, Naruto| Kajiwara, Yukiko| Iwamoto, Takayuki| Kitaguchi, Yohei| Saiga, Miho| Watanabe, Satoko| Shien, Tadahiko| Doihara, Hiroyoshi| Kimata, Yoshihiro| |
| 抄録 | Although immediate breast reconstruction following mastectomy has become increasingly common, its oncological safety has been debated. We enrolled patients with breast cancer who underwent surgery at Okayama University Hospital between 2007 and 2013. The primary outcome was relapse-free survival (RFS). Secondary outcomes were overall survival and the duration from the surgery to the initiation of adjuvant chemotherapy. We divided into immediate breast reconstruction, mastectomy alone, and breast conservative surgery groups. Outcomes were compared using Cox’s regression analysis. A total of 614 patients were included (reconstruction: 125, mastectomy: 128, breast conservative surgery: 361). The median follow-up duration was 79.0±31.9 months. The immediate-reconstruction patients were younger, had more lymph node metastases, and more often received postoperative chemotherapy. The RFS was better after the breast conservative surgery compared to after reconstruction (hazard ratio 0.33, 95% confidence interval: 0.144-0.763). The proportion of local recurrence was highest in the reconstruction group. No patients in the reconstruction group underwent postoperative radiation therapy. However, reconstruction did not affect overall survival or the time to the initiation of adjuvant chemotherapy. Surgeons should explain the risks of breast reconstruction to their patients preoperatively. Careful long-term follow-up is required after such procedures. |
| キーワード | immediate breast reconstruction oncological safety local recurrence postoperative radiation therapy time to initiation of adjuvant chemotherapy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 281 |
| 終了ページ | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357629 |
| Web of Science KeyUT | 001026279600006 |
| JaLCDOI | 10.18926/AMO/65492 |
|---|---|
| フルテキストURL | 77_3_273.pdf |
| 著者 | Shimizu, Yudai| Kuroda, Masahiro| Nakamitsu, Yuki| Al-Hammad, Wlla E.| Yoshida, Suzuka| Fukumura, Yuka| Nakamura, Yoshihide| Kuroda, Kazuhiro| Kamizaki, Ryo| Imajoh, Satoshi| Tanabe, Yoshinori| Sugimoto, Kohei| Oita, Masataka| Sugianto, Irfan| Bamgbose, Babatunde O.| Yanagi, Yoshinobu| Asaumi, Junichi| |
| 抄録 | Diffusion kurtosis (DK) imaging (DKI), a type of restricted diffusion-weighted imaging, has been reported to be useful for tumor diagnoses in clinical studies. We developed a software program to simultaneously create DK images with apparent diffusion coefficient (ADC) maps and conducted an initial clinical study. Multi-shot echo-planar diffusion-weighted images were obtained at b-values of 0, 400, and 800 sec/mm2 for simple DKI, and DK images were created simultaneously with the ADC map. The usefulness of the DK image and ADC map was evaluated using a pixel analysis of all pixels and a median analysis of the pixels of each case. Tumor and normal tissues differed significantly in both pixel and median analyses. In the pixel analysis, the area under the curve was 0.64 for the mean kurtosis (MK) value and 0.77 for the ADC value. In the median analysis, the MK value was 0.74, and the ADC value was 0.75. The MK and ADC values correlated moderately in the pixel analysis and strongly in the median analysis. Our simple DKI system created DK images simultaneously with ADC maps, and the obtained MK and ADC values were useful for differentiating head and neck tumors from normal tissue. |
| キーワード | simple diffusion kurtosis imaging mean kurtosis clinical trial head and neck tumor magnetic resonance imaging |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 273 |
| 終了ページ | 280 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357628 |
| Web of Science KeyUT | 001026279600005 |
| JaLCDOI | 10.18926/AMO/65491 |
|---|---|
| フルテキストURL | 77_3_263.pdf |
| 著者 | Guo, Yusheng| Kosaka, Junko| Morimatsu, Hiroshi| |
| 抄録 | Continuous renal replacement therapy (CRRT) is widely used to control fluid balance, but the optimal fluid balance to improve the prognosis of patients remains debated. Appropriate fluid management may depend on hemodynamic status. We investigated the association between 90-day mortality and fluid balance/mean arterial pressure (MAP) in patients receiving CRRT. This single-center retrospective study was conducted between May 2018 and March 2021. Based on the cumulative fluid balance at 72 h after initiation of CRRT, the cases were divided into negative (< 0 mL) and positive (> 0 mL) fluid balance groups. Ninety-day mortality was higher in the positive fluid balance group (p=0.009). At 4 h before and after CRRT initiation, the mean MAP was lower in the positive fluid balance group (p<0.05). After multivariate cox adjustment, 72-h positive fluid balance was independently associated with 90-day mortality (p=0.004). In addition, the cumulative fluid balance was associated with 90-day mortality (p<0.05) in cases without shock, high APACHE II score, sepsis, dialysis dependence, or vasopressor use. A 72-h positive fluid balance was associated with 90-day mortality in patients receiving CRRT. |
| キーワード | fluid management continuous renal replacement therapy mortality mean arterial pressure daily cumulative fluid balance |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 263 |
| 終了ページ | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357627 |
| Web of Science KeyUT | 001026279600004 |
| JaLCDOI | 10.18926/AMO/65490 |
|---|---|
| フルテキストURL | 77_3_255.pdf |
| 著者 | Fukushima, Shinnosuke| Hagiya, Hideharu| Uda, Kazuhiro| Gotoh, Kazuyoshi| Otsuka, Fumio| |
| 抄録 | Antimicrobial resistance is an emerging global threat that must be addressed using a multidisciplinary approach. This study aimed to raise awareness of high-level antimicrobial-resistant (AMR) pathogens in Japan by comparing their recent prevalences among prefectures, particularly Okayama. Data for the isolation proportions of meropenem-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae, and levofloxacin-resistant E. coli and K. pneumoniae were collected from the Japan Nosocomial Infections Surveillance, a national database sponsored by the Japanese Ministry of Health, Labour, and Welfare, between 2018 and 2021. The average isolated proportions of the seven AMR pathogens were higher in Okayama compared to other prefectures: the worst (19.9%) was meropenem-resistant P. aeruginosa, the sixth worst (57.2%) was methicillin-resistant S. aureus, the eighth worst (3.3%) was vancomycin-resistant E. faecium, the second (37.8%) and fifth worst (17.6%) were cefotaxime-resistant E. coli and K. pneumoniae, respectively, and the fourth (49.9%) and third worst (8.7%) were levofloxacin-resistant E. coli and K. pneumoniae, respectively. Our study highlights the notably high prevalences of representative AMR pathogens in Okayama, suggesting the need for fundamental infection prevention and control by healthcare professionals, promoting antimicrobial stewardship, and educating undergraduates and postgraduates in Okayama. |
| キーワード | antimicrobial resistance antimicrobial stewardship epidemiology infection prevention and control Japan Nosocomial Infections Surveillance |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 255 |
| 終了ページ | 262 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357626 |
| Web of Science KeyUT | 001026279600003 |
| JaLCDOI | 10.18926/AMO/65489 |
|---|---|
| フルテキストURL | 77_3_243.pdf |
| 著者 | Shibata, Yusuke| Eguchi, Jun| Wada, Jun| |
| 抄録 | Brown adipose tissue (BAT) plays a critical role in metabolic homeostasis. BAT dysfunction is associated with the development of obesity through an imbalance between energy expenditure and energy intake. The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis. However, the roles of PPARγ and thiazolidinediones (TZDs) in the regulation of BAT metabolism remain unclear. TZDs, which are selective PPARγ activators, improve systemic insulin resistance in animals and humans. In the present study, we generated brown adipocyte-specific PPARγ-deficient mice (BATγKO) to examine the in vivo roles of PPARγ and TZDs in BAT metabolism. In electron microscopic examinations, brown adipocyte-specific PPARγ deletion promoted severe whitening of brown fat and morphological alteration of mitochondria. Brown adipocyte-specific PPARγ deletion also reduced mRNA expression of BAT-selective genes. Although there was no difference in energy expenditure between control and BATγKO mice in calorimetry, norepinephrine-induced thermogenesis was impaired in BATγKO mice. Moreover, pioglitazone treatment improved diet-induced insulin resistance in the control mice but not in the BATγKO mice. These findings suggest that BAT PPARγ is necessary for the maintenance of brown adipocyte function and for the insulin-sensitizing action of TZDs. |
| キーワード | PPARγ brown adipose tissue thiazolidinediones |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 243 |
| 終了ページ | 254 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357625 |
| Web of Science KeyUT | 001026279600002 |
| JaLCDOI | 10.18926/AMO/65488 |
|---|---|
| フルテキストURL | 77_3_235.pdf |
| 著者 | Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki| |
| 抄録 | Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users. |
| キーワード | anamorelin body weight cancer cachexia endocrine system |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-06 |
| 巻 | 77巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 235 |
| 終了ページ | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37357624 |
| Web of Science KeyUT | 001026279600001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Inaba, Mototaka| Naito, Hiromichi| Yorifuji, Takashi| Nakamichi, Chikaaki| Maeyama, Hiroki| Ishikawa, Hideki| Shime, Nobuaki| Uemori, Sadayori| Ishihara, Satoshi| Takaoka, Makoto| Ohtsuka, Tsuyoshi| Harada, Masahiro| Nozaki, Satoshi| Kohama, Keisuke| Sakurai, Ryota| Sato, Shuho| Muramatsu, Shun| Yamashita, Kazunori| Mayumi, Toshihiko| Aita, Kaoruko| Nakao, Atsunori| the LIFE Study Investigators| |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-32519-2| |
| 発行日 | 2023-04-03 |
| 出版物タイトル | Scientific Reports |
| 巻 | 13巻 |
| 号 | 1号 |
| 出版者 | nature portfolio |
| 開始ページ | 5433 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 37012346 |
| DOI | 10.1038/s41598-023-32519-2 |
| Web of Science KeyUT | 000984090500023 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-023-32519-2 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Takata, Jun| Kiura, Katsuyuki| Nakasuka, Takamasa| Hirabae, Atsuko| Arimoto-Kobayashi, Sakae| |
| キーワード | Anti-mutagenesis Signal transduction Lung tumorigenesis DNA methylation Tobacco-specific nitrosamine Glycine betaine |
| 備考 | The version of record of this article, first published in Genes and Environment, is available online at Publisher’s website: http://dx.doi.org/10.1186/s41021-023-00276-3| |
| 発行日 | 2023-06-07 |
| 出版物タイトル | Genes and Environment |
| 巻 | 45巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 19 |
| ISSN | 1880-7046 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 37280663 |
| DOI | 10.1186/s41021-023-00276-3 |
| Web of Science KeyUT | 001002195100001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s41021-023-00276-3 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | 本田 恭子| 松岡 崇暢| 岩本 光一郎| |
| キーワード | 再生可能エネルギー 小水力発電 農業協同組合 コミュニティ・パワー ステークホルダー |
| 発行日 | 2017-06 |
| 出版物タイトル | 地域地理研究 |
| 巻 | 23巻 |
| 号 | 1号 |
| 出版者 | 地域地理科学会 |
| 開始ページ | 18 |
| 終了ページ | 33 |
| ISSN | 21878277 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| フルテキストURL | esr_029_cover_j.pdf |
|---|---|
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2023-03-31 |
| 巻 | 29巻 |
| 号 | 1号 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2023 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| フルテキストURL | esr_029_colophon.pdf |
|---|---|
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2023-03-31 |
| 巻 | 29巻 |
| 号 | 1号 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2023 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| タイトル（別表記） | ERRATA: FDM simulation of long-period ground motions around Oita Prefecture, Japan, using a land-ocean unified 3D structure model |
|---|---|
| フルテキストURL | esr_029_065_066.pdf |
| 著者 | 奥仲 達也| 小松 正直| 竹中 博士| 吉見 雅行| 中村 武史| 岡元 太郎| |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2023-03-31 |
| 巻 | 29巻 |
| 号 | 1号 |
| 開始ページ | 65 |
| 終了ページ | 66 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2023 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/ESR/65481 |
|---|---|
| タイトル（別表記） | Onset time and location of the main rupture of the 2018 Hokkaido Eastern Iburi, Japan, earthquake |
| フルテキストURL | esr_029_049_063.pdf |
| 著者 | 小割 啓史| 小松 正直| 竹中 博士| |
| 抄録 | The rupture process at the beginning stage of the 2018 Hokkaido Eastern Iburi, Japan, earthquake (MJ 6.7) is investigated by analyzing P-wave records from local strong-motion stations. The records show about 3 s of small amplitude arrival (so-called "initial rupture phase") followed by the onset of the main energy release ("main rupture phase"). In this paper we address the issue: where the seismic energy release corresponding to the main rupture phase started at the primary stage of the main rupture, by locating the main rupture onset position. For this aim we applied the 2D and the 3D search methods to estimate the relative location of the onset of the main rupture with respect to the hypocenter, and the time difference between them. The 2D method assumes a plausible initial fault plane and locates the main rupture onset position on the initial fault plane, while the 3D method does not require such assumed fault planes. In the 2D method we employed each of the nodal planes of the first-motion focal mechanism as the initial rupture plane. The 3D method was able to give a better solution than the 2D one. It suggests that the main rupture initiation point might not be on the same fault plane as the hypocenter is. The solution shows that the main rupture onset point is 5.8 km southward and 2.5 km upward from the hypocenter, with the rupture time of 3.3 s from the origin time. It is consistent with the previous studies on the relationship between the magnitude and the initial rupture duration. |
| キーワード | 2018 Hokkaido Eastern Iburi earthquake fault plane initial rupture strong motion |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2023-03-31 |
| 巻 | 29巻 |
| 号 | 1号 |
| 開始ページ | 49 |
| 終了ページ | 63 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2023 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |