| ID | 18243 |
| Eprint ID | 18243
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| フルテキストURL | |
| タイトル（別表記） | Studies on Leukemogenesis in RF Mice by Oral Administration of 20-methylcholanthrene. I. Co-leukemogenic Action of Croton Oil in the Induction of Leukemia by Oral Administration of 20-methylcholanthrene
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| 著者 |
康 逸雄
岡山大学大学院医学研究科
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| 抄録 | 1) Myelogenous and lymphocytic leukemias were observed among mice given orally three times a week 0.1-0.15cc of 0.8% 20-methylcholanthrene in olive oil by means of a needle catheter and concurrently painted in the back two times a week with 5% croton oil in benzene. 2) The incident of leukemias was 61.6% for myelogenous and 5.5% for lymphocytic leukemia with a total of 66.6%. On the other hand, mice receiving croton oil alone developed no leukemia. 3) Concurrent administration of 20-methylcholanthrene and croton oil reduced the average latent period required for the development of leukemia by about four weeks in comparison with that of 20-methylcholanthrene treatment alone. 4) From these results, it is concluded that croton oil is coleukemogenic, acting as a promoter in the 20-methylcholanthrene leukemogenesis in mice.
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| 発行日 | 1964-03-30
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| 出版物タイトル |
岡山医学会雑誌
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| 出版物タイトル（別表記） | Journal of Okayama Medical Association
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| 巻 | 76巻
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| 号 | 1-3号
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| 出版者 | 岡山医学会
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| 出版者（別表記） | Okayama Medical Association
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| 開始ページ | 91
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| 終了ページ | 103
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| ISSN | 0030-1558
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| NCID | AN00032489
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| 資料タイプ |
学術雑誌論文
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| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/76/1-3/76_1-3_91/_article/-char/ja/
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/
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| 言語 |
日本語
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| 著作権者 | 岡山医学会
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| 論文のバージョン | publisher
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| 査読 |
有り
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| Eprints Journal Name | joma
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