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タイトル(別表記) Drug interaction (30. combination with therapeutic drugs for chronic pain)
フルテキストURL 126_159.pdf
著者 小川 敦| 北村 佳久| 千堂 年昭|
出版物タイトル 岡山医学会雑誌
発行日 2014-08-01
126巻
2号
開始ページ 159
終了ページ 163
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.159
NAID 130004685269
フルテキストURL K0004883_abstract_review.pdf.pdf K0004883_fulltext.pdf
著者 佐古 真一|
発行日 2014-03-25
資料タイプ 学位論文
学位授与番号 甲第4883号
学位授与年月日 2014-03-25
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 日本語 英語
JaLCDOI 10.18926/AMO/52406
フルテキストURL 68_2_101.pdf
著者 Izutsu, Masato| Suzuki, Etsuji| Izutsu, Yukako| Doi, Hiroyuki|
抄録 The aim of this study was to examine trends in the geographic distribution of nursing staff in Japan from 2000 to 2010. We examined time trends in the rates of nursing staff per 100,000 population across 349 secondary health service areas. Using the Gini coefficient as a measure of inequality, we separately analyzed the data of 4 nursing staff types:public health nurses (PHN), midwives (MW), nurses (NS), and associate nurses (AN). Then, using multilevel Poisson regression models, we calculated the rate ratios (RRs) and their 95% confidence intervals (CIs) for each type of nursing staff per 1-year change. Overall, the distribution of PHN, MW, and NS improved slightly in terms of the Gini coefficient. After adjusting for prefectural capital and population density, PHN, MW, and NS significantly increased;the RRs per 1-year increment were 1.022 (95% CI:1.020-1.023), 1.021 (95% CI:1.019-1.022), and 1.037 (95% CI:1.037-1.038), respectively. In contrast, AN significantly decreased;the RR per 1-year increment was 0.993 (95% CI:0.993-0.994). Despite the considerable increase in the absolute number of nursing staff in Japan (excluding AN), this increase did not lead to a sufficient improvement in distribution over the last decade.
キーワード health policy inequality Japan multilevel Poisson model nursing staff
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-04
68巻
2号
出版者 Okayama University Medical School
開始ページ 101
終了ページ 110
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24743785
Web of Science KeyUT 000334652700005
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/52523
JaLCDOI 10.18926/AMO/52405
フルテキストURL 68_2_89.pdf
著者 Sako, Shinichi| Kariyama, Reiko| Mitsuhata, Ritsuko| Yamamoto, Masumi| Wada, Koichiro| Ishii, Ayano| Uehara, Shinya| Kokeguchi, Susumu| Kusano, Nobuchika| Kumon, Hiromi|
抄録 We conducted a study on molecular epidemiology and clinical implications of metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa isolated from urine. Over a 10-year period from 2001 through 2010, a total of 92 MBL-producing P. aeruginosa urine isolates were collected from patients (one isolate per patient) who were admitted to 5 hospitals in Okayama Prefecture, Japan. When cross-infection was suspected in the hospital, pulsed-field gel electrophoresis was performed. In the resulting dendrogram of 79 MBL-producing P. aeruginosa urine isolates, no identical isolates and 7 pairs of isolates with ≥80% similarity were found. The biofilm-forming capabilities of 92 MBL-producing P. aeruginosa urine isolates were significantly greater than those of 92 non-MBL-producing urine isolates in a medium of modified artificial urine. The imipenem resistance transferred in 16 of 18 isolates tested, and these frequencies were in the range of 10-3 to 10-9. All of 18 isolates tested belonged to internationally spread sequence type 235 and had 3 gene cassettes of antimicrobial resistance genes in the class 1 integron. The strong biofilm-forming capabilities of MBL-producing P. aeruginosa urine isolates could be seriously implicated in nosocomial infections. To prevent spread of the organism and transferable genes, effective strategies to inhibit biofilm formation in medical settings are needed.
キーワード Pseudomonas aeruginosa metallo-β-lactamase molecular epidemiology biofilm urinary tract infection
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-04
68巻
2号
出版者 Okayama University Medical School
開始ページ 89
終了ページ 99
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24743784
Web of Science KeyUT 000334652700004
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/52504
著者 Sugiyama, Koichi| Sada, Ken-ei| Kurosawa, Michiko| Wada, Jun| Makino, Hirofumi|
発行日 2013-02
出版物タイトル Clinical and Experimental Nephrology
17巻
1号
資料タイプ 学術雑誌論文
タイトル(別表記) SFTS : Severe fever with thrombocytopenia syndrome
フルテキストURL 126_65.pdf
著者 渡邉 都貴子| 草野 展周| 岩月 啓氏|
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
126巻
1号
開始ページ 65
終了ページ 67
ISSN 0030-1558
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.65
タイトル(別表記) Metastatic breast cancer presenting as severe anemia, platelet reduction and abnormal cells in peripheral blood
フルテキストURL 126_31.pdf
著者 太田 誠介| 笠原 明宣| 水野 翔馬| 深津 遥香| 木下 修| 野口 敏生| 岸本 信康| 松村 正|
抄録  Worldwide, breast cancer accounts for 22.9% of all cancers excluding non-melanoma skin cancers in women. More than 80% of breast cancer cases are discovered when a woman discovers a lump that feels different from the rest of the breast tissue. We report the case of a 60-year-old woman who had been treated for one year at a psychiatric hospital for suspected schizophrenia, and was referred to our hospital on March 23, 2011 for consultation regarding complete blood count abnormalities: hemoglobin, 4.8g/㎗ ; Plt, 1.9×104/μl ; WBC, 12,700/μl with 18.5% abnormal cells. Computed tomography revealed an enhanced, irregular mass in her right breast as well as right axillary lymph node swelling, suggestive of breast cancer. BM biopsy confirmed the presence of abnormal, keratin-positive cells, suggesting metastasis to the bone. CA15-3 was 300U/㎖ (normal range <25). The patient died on April 11, 2011, post-admission day 20. We found a rare case of terminal breast cancer that presented with peripheral blood abnormality. Breast cancer in patients who do not notice breast abnormality can present with peripheral blood abnormality.
キーワード 乳癌(breast cancer) 初発症状(initial symptom) 貧血(anemia) 骨髄転移(bone marrow metastasis)
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
126巻
1号
開始ページ 31
終了ページ 34
ISSN 0030-1558
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.31
JaLCDOI 10.18926/AMO/52141
フルテキストURL 68_1_27.pdf
著者 Yoshida, Masao| Ishikawa, Mamoru| Karita, Kanae| Kokaze, Akatsuki| Harada, Matsuko| Take, Shinichiro| Ohno, Hideki|
抄録 To clarify whether high blood pressure (BP) and high body mass index (BMI) are associated with elevated intraocular pressure (IOP), a cross-sectional and longitudinal study was conducted. This epidemiological study analyzed health examination data obtained between 2001 and 2005 from 896 Japanese individuals (aged 32-79 years) who had not undergone any ocular surgery or medical treatment for hypertension, ocular hypertension, or glaucoma. Multiple-regression analysis of our cross-sectional data showed that systolic and diastolic BP (SBP and DBP) and BMI had significant and near-significant positive associations with IOP in men (p<0.05) and women (p<0.1). Our longitudinal study from analyses of covariance found that the adjusted mean level of changes in IOP tended to increase with increased levels of SBP, DBP, and BMI in men (p<0.1). In women also, changes in SBP and BMI tended to be positively related with that of IOP (p<0.1). The results of this study suggested that BP and BMI were positively associated with IOP in middle-aged and older Japanese. Therefore, management of BP and improvement of obesity might be especially important to Japanese patients with open-angle glaucoma or ocular hypertension as they have a higher incidence of normal-tension glaucoma than Europeans and Americans.
キーワード intraocular pressure blood pressure body mass index epidemiology glaucoma
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 27
終了ページ 34
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553486
Web of Science KeyUT 000331592800005
JaLCDOI 10.18926/AMO/51066
フルテキストURL 67_4_219.pdf
著者 Maruyama, Hidehiko| Nakamura, Makoto| Yonemoto, Naohiro| Kageyama, Misao|
抄録 Cholestasis and thrombocytopenia are complications that affect infants born small for gestational age (SGA). In SGA infants, other vital organs develop at the expense of the liver, and the thrombopoietin produced by the liver is low, often resulting in cholestasis. We hypothesized that thrombocytopenia at birth can be used to predict cholestasis in very-low-birth-weight infants (VLBWIs) with SGA. This retrospective cohort study enrolled VLBWIs with SGA admitted to a tertiary neonatal intensive care unit. A platelet cutoff value predictive of cholestasis was determined using receiver operating characteristic analysis. Multivariate logistic regression analysis was performed to evaluate the platelet cutoff value, and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Regarding the onset of cholestasis, survival analysis was performed by calculating the adjusted hazard ratios (HRs) and 95% CIs. A total of 87 infants were evaluated, and the platelet cutoff value was determined as 88×10(3) cells/μl. The adjusted OR for this platelet cutoff value was 10.52 (95% CI 2.26-55.93, p=0.003), and the adjusted HR was 7.76 (95% CI 2.51-23.50, p=0.0006). Thrombocytopenia is a useful predictor for cholestasis in VLBWIs with SGA.
キーワード cholestasis platelet small for gestational age thrombocytopenia very low birth weight
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2013-08
67巻
4号
出版者 Okayama University Medical School
開始ページ 219
終了ページ 225
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23970320
Web of Science KeyUT 000323470100003
著者 Kawagoe, Seiji| Tsuda, Toshihide| Doi, Hiroyuki|
発行日 2012-12-26
出版物タイトル Geriatrics & Gerontology Internationa
資料タイプ 学術雑誌論文
著者 萩谷 英大| 塩田 澄子| 三好 伸一| 黒江 泰利| 野島 宏悦| 大谷 晋吉| 杉山 淳一| 内藤 宏道| 川西 進| 萩岡 信吾| 森本 直樹|
発行日 2013-04-01
出版物タイトル 岡山医学会雑誌
125巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/49254
フルテキストURL 67_1_25.pdf
著者 Ika, Katsuhiko| Suzuki, Etsuji| Mitsuhashi, Toshiharu| Takao, Soshi| Doi, Hiroyuki|
抄録 The purpose of this study was to examine the association between shift work and diabetes mellitus by separating shift workers according to the intensity of their shift work (seasonal shift work and continuous shift work). Between May and October 2009, we collected data from annual health checkups and questionnaires at a manufacturing company in Shizuoka, Japan. Questionnaires were returned by 1,601 workers (response rate:96.2%, men/women=1,314/287). Diabetes mellitus was defined as hemoglobin A1c≥6.5% and fasting blood sugar≥126mg/dl. After exclusions, which included all the women and clerical workers because they did not work in shifts, we analyzed 475 skilled male workers. After adjusting for age, smoking status, frequency of alcohol consumption, and cohabitation status, odds ratios for diabetes mellitus were 0.98 (95% confidence interval [CI]:0.28-4.81) and 2.10 (95% CI:0.77-5.71) among seasonal shift workers and continuous shift workers, respectively, compared with non-shift workers. In an age-stratified analysis (<45 years vs.≥45 years), the association between continuous shift work and diabetes mellitus was more pronounced among older participants. Compared with non-shift workers, the risk of diabetes mellitus was increased among continuous shift workers, whereas its effect is limited among seasonal shift workers.
キーワード cross-sectional study diabetes mellitus intensity Japan shift work
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2013-02
67巻
1号
出版者 Okayama University Medical School
開始ページ 25
終了ページ 33
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23439506
Web of Science KeyUT 000316829900004
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/50693
JaLCDOI 10.18926/AMO/49040
フルテキストURL 66_6_443.pdf
著者 Ugawa, Toyomu| Sakurama, Kazufumi| Yorifuji, Takashi| Takaoka, Munenori| Fujiwara, Yasuhiro| Kabashima, Narutoshi| Azuma, Daisuke| Hirayama, Takahiro| Tsukahara, Kohei| Morisada, Sunao| Iida, Atsuyoshi| Tada, Keitaro| Shiba, Naoki| Sato, Nobuo| Ichiba, Shingo| Kino, Koichi| Fukushima, Masaki| Ujike, Yoshihito|
抄録 The functioning of an arteriovenous fistula (AVF) used for vascular access during hemodialysis has been assessed mainly by dilution methods. Although these techniques indicate the immediate recirculation rate, the results obtained may not correlate with Kt/V. In contrast, the clearance gap (CL-Gap) method provides the total recirculation rate per dialysis session and correlates well with Kt/V. We assessed the correlation between Kt/V and CL-Gap as well as the change in radial artery (RA) blood flow speed in the fistula before percutaneous transluminal angioplasty (PTA) in 45 patients undergoing continuous hemodialysis. The dialysis dose during the determination of CL-Gap was 1.2 to 1.4 Kt/V. Patients with a 10% elevation or more than a 10% relative increase in CL-Gap underwent PTA (n=45), and the values obtained for Kt/V and CL-Gap before PTA were compared with those obtained immediately afterward. The mean RA blood flow speed improved significantly (from 52.9 to 97.5cm/sec) after PTA, as did Kt/V (1.07 to 1.30) and CL-Gap (14.1% to -0.2%). A significant correlation between these differences was apparent (r=-0.436 and p=0.003). These findings suggest that calculating CL-Gap may be useful for determining when PTA is required and for assessing the effectiveness of PTA, toward obtaining better dialysis.
キーワード hemodialysis recirculation clearance gap vascular access percutaneous transluminal angioplasty
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2012-12
66巻
6号
出版者 Okayama University Medical School
開始ページ 443
終了ページ 447
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23254578
Web of Science KeyUT 000312966100003
JaLCDOI 10.18926/AMO/48689
フルテキストURL 66_4_343.pdf
著者 Fujiwara, Takeo| Takao, Soshi| Iwase, Toshihide| Hamada, Jun| Kawachi, Ichiro|
抄録 Little is known about the association between social capital and child behaviors. This study aims to investigate that association. A complete population-based, cross-sectional survey was conducted for all the caregivers with preschool children in a rural town in Okayama prefecture in Japan. Two dimensions of individual-level social capital and unhealthy child behaviors were reported by parent-administered questionnaire. We analyzed 354 preschool children (57.6% of all children for whom questionnaires were completed). Children whose main caregiver had high cognitive social capital were 89% less likely to miss breakfast (odds ratio [OR]=0.11;95% confidence interval [CI]:0.01-1.03). Children whose caregiver had high structural social capital were 71% less likely to wake up late (OR=0.29;95% CI:0.12-0.71) and 78% less likely to skip tooth brushing more than once per day (OR=0.22;95% CI:0.05-0.93). Both cognitive and structural social capital were negatively associated with unhealthy child behaviors. A further intervention study is needed to confirm the impact of social capital on child behavior.
キーワード tooth brushing child health social capital skipping breakfast watching TV
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2012-08
66巻
4号
出版者 Okayama University Medical School
開始ページ 343
終了ページ 350
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22918207
Web of Science KeyUT 000307918900007
タイトル(別表記) A Study on Asbestos Litigation (1):Focusing on Epidemiologic Causality
フルテキストURL olj_057_2_399_412.pdf
著者 辻 博明|
出版物タイトル 岡山大學法學會雜誌
発行日 2007-12-28
57巻
2号
開始ページ 399
終了ページ 412
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 40015825562
タイトル(別表記) A Study on Asbestos Litigation (2): Focusing on Epidemiologic Causality
フルテキストURL olj_058_2_231_267.pdf
著者 辻 博明|
出版物タイトル 岡山大學法學會雜誌
発行日 2008-12-26
58巻
2号
開始ページ 231
終了ページ 267
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 40016456516
タイトル(別表記) A Study on Asbestos Litigation (3) : Focusing on Epidemiologic Causality
フルテキストURL olj_059_1_133_156.pdf
著者 辻 博明|
出版物タイトル 岡山大學法學會雜誌
発行日 2009-09-04
59巻
1号
開始ページ 133
終了ページ 156
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 40016845507
タイトル(別表記) A Study on Asbestos Litigation (5) : Focusing on Epidemiologic Causality
フルテキストURL olj_060_2_313_339.pdf
著者 辻 博明|
出版物タイトル 岡山大學法學會雜誌
発行日 2010-12-24
60巻
2号
開始ページ 313
終了ページ 339
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 40018267387
タイトル(別表記) A Study on Asbestos Litigation (4) : Focusing on Epidemiologic Causality
フルテキストURL olj_060_1_125_140.pdf
著者 辻 博明|
出版物タイトル 岡山大學法學會雜誌
発行日 2010-08-25
60巻
1号
開始ページ 125
終了ページ 140
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 40017296180
タイトル(別表記) A Study on Asbestos Litigation(6): Focusing on Epidemiologic Causality
フルテキストURL olj_060_3_517_530.pdf
著者 辻 博明|
出版物タイトル 岡山大學法學會雜誌
発行日 2011-02-28
60巻
3号
開始ページ 517
終了ページ 530
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 40018778998