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著者 水野 修|
発行日 2010-03-25
出版物タイトル
資料タイプ 学位論文
JaLCDOI 10.18926/21202
タイトル(別表記) Circulatory changes in rheumatoid fingers as estimated by thermography and photoelectric plethysmography
フルテキストURL pitser_046_015_023.pdf
著者 太田 隆正| 時岡 正明| 高杉 潔|
抄録 In an attempt to evaluate circulatory changes in patients with rheumatoid arthritis (RA), 20 patients with classical or definite RA as determined by ARA criteria and twenty healthy volunteers serving as control were randomly selected. None of the patients showed the clinical signs suggesting Raynaud's phenomenon. Thermograms as well as photoelectric plethysmograms were obtained solely from the right middle finger tip of each examinee. The whole hand was then immersed in the cold (10℃) water and kept there for one minute. After wiping away the wet hand with a dry towel very gently, we followed the sequential changes of the tempe· rature of the third finger tip and the period of time necessary for the tip to return to the original temperature prior to the cold water immersion was measured and expressed as 'return time' in minute. Before exposure to the cold, the mean values of temperature of the finger tips between the two groups were not significantly different. As opposed to the normal pattern in which one can find the warmest point at the finger tip and which was more frequently found in the control group of the current study, a type in which the distal part of the finger was much cooler than the proximal area (so-called 'distal cold type') was observed in 8 RA patients, whereas only four demonstrated this pattern in the control group. After brief exposure to the cold, eight out of 20 rheumatoid patients showed much prolonged return time (longer than 20 minutes), while only three of 20 controls remained with prolonged cool periphery, The difference between the two, however, was not statistically significant. Studies of the digital plethysmograph revealed that 70% of all the rheumatoids showed abnormal patterns: sclerotic and monophasic waves were discovered in 55% of the patients. In contrast, seventy percent of the normal control demonstra· ted normal wave pattern. Although the significant difference was not noted, the mean height of the systolic peak of the plethysmograph derived from the rheumatoid group tended to be much reduced, suggesting the reduced blood volume at the finger tips. Six RA patients and 13 normals who showed normal plethysmographic pattern before immersion in the cold water, demonstrated rapid return to the original temperature. Only in one normal control with a normal wave pattern, prolonged return time was observed, although the height of the systolic peak of the plethysmogram in this particular case was well within normal limit. Digital circulatory disturbance, however, was strongly suspected in eight RA patients with severely prolonged return time, They all showed abnormal wave patterns of the plethysmogram, including 2 cases with peripheral plateau wave, Markedly reduced heights of the systolic peaks were also demonstrated in all. Further elaborate studies including digital arteriography were indicated to implicate any organic change in the digital vessels, such as digital arteritis in RA first reported by Bywaters in 1957.
出版物タイトル 岡山大学温泉研究所報告
発行日 1977-03-25
46巻
開始ページ 15
終了ページ 23
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002310966
JaLCDOI 10.18926/21192
タイトル(別表記) Enumeration of T-cells in peripheral blood as well as in joint fluid from patients with rheumatoid arthritis (RA) and the effect of cyclophosphamide
フルテキストURL pitsr_047_041_048.pdf
著者 時岡 正明| 高杉 潔|
抄録 Gradient centrifugation was quite useful in obtaining "mononuclear" cell fractions from synovial fluids derived from patients with rheumatoid arthritis. The ratio of lymphocytes to monocytoid cells was similar to that seen in peripheral blood. Prior treatment of the fluid with hyaluronidase was found to be necessary to obtain a satisfactory yield of the cells. Sheep erythrocyte rosette-forming lymphocytes (T-cells) were studied in 18 paired samples of synovial fluid and blood in RA and 15 control blood samples from normal persons were also examined. In the paired synovial fluid and blood samples from the RA patients, the mean percentages of the T-cells were 56.6 and 47.1 respectively and the difference was statistically significant (0.01
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 41
終了ページ 48
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002310963
JaLCDOI 10.18926/21189
タイトル(別表記) The involvement of ear and throat in rheumatoid arthritis I. Hearing in patients with rheumatoid arthritis
フルテキストURL 047_005_024.pdf
著者 小田 昤|
抄録 Since Copeman's report on patients with hearing impairment as "rheumatoid otoarthritis?" has introduced, there have been a few reports on hearing impairment in patients with rheumatoid arthritis such as Goodwill et al. and Djupesland et aI. in European countries. On the contrary in our country there is no reference in association with hearing impairment of rheumatoid arthritis in rheumatic or otological literatures. An audiometric survey was carried out in 76 patients admitted in the Misasa branch hospital of Okayama university school of medicine on the classical or definite rheumatoid arthritis. Patients were excluded from the series if they had scarred or perforated tympanic membrane and history of otorrhea. Thus 67 patients have come to study. As control group, 15 healthy persons in hearing for each ten years, 15-24, 25-34, 35-44, 45-54, 55-64, and over 60 years, were selected and as a physiological hearing limit, rejection limit of hearingloss in dB. was made. Among 67 patients, 111 ears had hearingloss within the above mentioned rejection limit. In 23 ears, hearingloss in dB. were partial or as a whole out of the limit. They have all air-bone-conduction gap. After inflation of Eustachien tube, in most of them air conduction ability showed nearly the same level of bone conduction. In three cases even by inflation, airconduction level did not move. In one case the left side had effusion liquid and its RAreaction was positive. TwO of the former patients and the one whose effusion liquid had positive RA-test followed up for about 3 years. In the former two cases, hearing impairment got worse little by little and recovery by inflation was not seen. On both cases Gelle's test was positive. In the latter hearing impairment slowly got worse. This had lasted for about two months and had recoverd. In the se four cases heairng impairment was probably related to the rheumatoid arthritis and no other causes could be found.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 5
終了ページ 24
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002311022
JaLCDOI 10.18926/21182
タイトル(別表記) Prevalence of periCardial effusion in patients with rheumatoid arthritis -An echocardiographic study-
フルテキストURL pitsr_048_049_054.pdf
著者 石井 廣文| 道明 道弘| 田中 淳太郎| 高杉 潔|
抄録 In order to determine the incidence of pericardial effusion in rheumatoid arthritis (RA), echocardiographic studies were performed on patients with classical or definite RA as determined by ARA criteria, none of whom showed any clinical cardiac symptoms at the time of examination. Of 50 RA patients studied so far, fifteen (30%) showed evidence of posterior pericardial effusion, as recorded on the strip charts. Additionally, in one full-blown case of rheumatoid vasculitis, massive accumulation of pericardial fluid was demonstrable. Compared to those without pericardial effusion, patients shown to have pericardial fluid tended to have decreased RBC, Hct, Hgb, serum protein concentration and increased ESR. The statistical difference between the two groups was significant (P<0.005). The most conspicuous difference between the two, however, was noted in the degree of hypoalbuminemia that is more profound in the effusion positive group (P<0.005). The possible cause of fluid retention in the pericardial cavity in RA was briefly discussed.
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-03-25
48巻
開始ページ 49
終了ページ 54
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002310937
JaLCDOI 10.18926/21178
タイトル(別表記) Determination of copper and zinc in synovial fluid by atomic absorption spectrophotometry
フルテキストURL pitsr_048_013_023.pdf
著者 古野 勝志|
抄録 Copper (Cu) and zinc (Zn) in synovial fluids of 52 patients with rheumatoid arthritis (RA) and of 53 patients with osteoarthritis (OA) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Standard solution of Cu and Zn were 50μg, 100μg, 200μg and 300μg per 100 ml 20 v/v % glycerine containing 0.01 N-HCl. To 0.5ml synovial fluid, 50 units of hyaluronidase was added and then the mixture were incubated for 20 minutes at 37℃. Synovial fluid treated with hyaluronidase and standard solution of Cu and Zn were diluted five fold with deionized distillation water, then aspirated directly into the burner. The relative absorbance was expressed as scale reading by a HITACHI MODEL QPD-54 recoder. The mean recovery rate of Cu and Zn in synovial fluids were 102.0% and 101.9%. By this method the concentrations of Cu and Zn in 52 RA (12 males, 40 females) were 97.6±29.0 (S.D.) μg/100 ml and 83.9±40.1 (S.D.) μg/100 ml ; 97.3±27.1 (S.D.)μg/100 ml, 78.7±29.9 (S.D.) μg /100 ml in 12males and 97.7±29.5 (S.D.) μg/100 ml, 85.5±42.6 (S.D.) μg /100 ml in 40 females respectively. The concentrations of Cu and Zn in 53 OA (14 males, 39 females) were 46.9±14.5 (S.D.) μg/100 ml and 40.8±14.3 (S.D.) μg/100 ml; 47.3±9.7 (S.D.) JLg/100 ml, 45.1±19.0 (S.D.) μg/ 100 ml in 14 males and 46.8±15.8 (S.D.) μg/100 ml, 39.3±11.8 (S.D.) μg/100 ml in 39 females respectively. No sex differences of Cu and Zn values were observed in both RA and OA. In patients with RA, concentrations of Cu and Zn in synovial fluids were signifcantly higher than in OA in both sexes. There were positive correlation between the concentrations of Cu and Zn in 105 patients (RA and OA, r=0.74, p<0.01) , in 52 RA (r=0.54, p<0.01), in 53 OA (r=0.81, p<0.01). In patients with RA, there were no correlation between stage and concentrations of Cu and Zn in synovial fluids.
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-03-25
48巻
開始ページ 13
終了ページ 23
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002311026
JaLCDOI 10.18926/21114
タイトル(別表記) Determination of ferritin in serum and in synovial fluids of patients with rheumatoid arthritis
フルテキストURL pitsr_053_001_008.pdf
著者 古野 勝志| 森永 寛| 入野 昭三|
抄録 Ferritin in sera and in synovial fluids were determined by method of immunoradiometric assay (IRMA) and of radioimmunoassay (RIA). These methods have been proved to be reproducible. The coefficient variation was 7.4 to 9.9% in IRMA and 5.6 to 8.0% in RIA. There were a good correlation between methods of IRMA and of RIA (r=0.989). The mean recovery rate of ferritin in serum was 101.2% in IRMA and 101.0% in RIA, respectively. The determination of serum ferritin revealed a 16% reduction in average after preservation at -20℃ during over 100 days. The levels of serum ferritin in healthy controls were 131.4±52.1 ng/ml in 34 males and 58.4±39.9 ng/ml in 38 females. The sex differences were statisticalIy significant (p<0.01). Ferritin levels were shown to be below 30 ng/ml (the state of iron deficiency) in 2 of 34 (5.9%) males and in 8 of 38 (21%) females of healthy controls. The levels of serum ferritin in patients with rheumatoid arthritis (RA) were 337.0±293.4ng/ml in 10 males and 181.4±329.9ng/ml in 25 females. The serum ferritin in RA was significantly higher than in healthy controls of both sexes. The levels of ferritin in synovial fluids of patients with 14 RA and with 12 osteoarthritis were 2894±3017 ng/ml and 1429±1005 ng/ml, and no differences were observed in both groups.
出版物タイトル 岡山大学温泉研究所報告
発行日 1983-03-25
53巻
開始ページ 1
終了ページ 8
ISSN 0369-7142
言語 日本語
論文のバージョン publisher
NAID 120002311016
著者 見尾 光庸| 鑛山 宗利| 多田 幹郎| 小野 文一郎| 蜂谷 欽司| 佐藤 公行|
発行日 1994-12-25
出版物タイトル 環境制御
16巻
資料タイプ 紀要論文
著者 有海 康雄| 黒木 美沙緒| 團迫 浩方| 阿部 健一| 池田 正徳| 脇田 隆字| 加藤 宣之|
発行日 2010-04-01
出版物タイトル 岡山医学会雑誌
122巻
1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/19687
タイトル(別表記) Studies on sinter deposits of misasa radioactive hot springs (3RD report)
フルテキストURL 057_046_055.pdf
著者 御船 政明| 妹尾 敏伸|
抄録 鳥取県三朝温泉岡大源泉の配湯管内の温泉沈殿物について既に報告されているが,今回採取した黒色の温泉沈殿物について発光分析法による定性分析を行ったところ,強放射性鉱物である北投石の主成分のBaが高濃度に検出されたので,岡大源泉(飲泉)水および沈殿物中の主要成分および放射能について調査した。温泉水のpHは6.97,Rn-222濃度は190.9Bq./kgで,Mn,Fe,Baの濃度は夫々0.011,0.018,0.021(mg/kg)であり,泉質は弱放射能-ナトリウム-塩化物泉に該当した。沈殿物中の主要成分はMn,Fe,Baで,その濃度は夫々363.5,148.0,69.6mg/gであり,このBa濃度は三朝温泉の温泉沈殿物中最高の濃度であった。しかしRa-226濃度は,既報程 度の3.30×10(-8)Ci/kgであった。
キーワード 三朝温泉 (Misasa hot springs) 温泉沈殿物 (Thermal sinter deposits) バリウム (Barium) ラジウム (Radium) ラドン (Radon)
出版物タイトル 環境病態研報告
発行日 1986-07
57巻
開始ページ 46
終了ページ 55
ISSN 09133771
関連URL http://eprints.lib.okayama-u.ac.jp/19952
言語 日本語
論文のバージョン publisher
NAID 120002309145
著者 三輪 泰彦|
発行日 1967-12-30
出版物タイトル 岡山医学会雑誌
79巻
11-12号
資料タイプ 学術雑誌論文
著者 須藤 千鶴子|
発行日 1972-10-30
出版物タイトル 岡山医学会雑誌
84巻
9-10号
資料タイプ 学術雑誌論文
著者 大原 敦|
発行日 1976-12-30
出版物タイトル 岡山医学会雑誌
88巻
11-12号
資料タイプ 学術雑誌論文
著者 大原 敦|
発行日 1976-12-30
出版物タイトル 岡山医学会雑誌
88巻
11-12号
資料タイプ 学術雑誌論文
著者 業天 洋三|
発行日 1975-10-30
出版物タイトル 岡山医学会雑誌
87巻
9-10号
資料タイプ 学術雑誌論文
著者 矢野 啓介|
発行日 1975-08-31
出版物タイトル 岡山医学会雑誌
87巻
7-8号
資料タイプ 学術雑誌論文
著者 堀井 城一朗|
発行日 2009-09-30
出版物タイトル
資料タイプ 学位論文
著者 平尾 謙| 河本 博文| 山本 和秀|
発行日 2009-12-01
出版物タイトル 岡山医学会雑誌
121巻
3号
資料タイプ 学術雑誌論文