検索結果 15921 件
| JaLCDOI | 10.18926/AMO/56653 |
|---|---|
| フルテキストURL | 73_2_173.pdf |
| 著者 | Tamada, Shoko| Masuyama, Hisashi| Hayata, Kei| Eto, Eriko| Mitsui, Takashi| Eguchi, Takeshi| Maki, Jota| Tani, Kazumasa| |
| 抄録 | Radical trachelectomy (RT) is a fertility-sparing surgery for cervical cancer. Postoperative pregnancies have a high risk of abortion and prematurity. To prevent this, a procedure involving transabdominal cerclage (TAC) was devised for shortened cervical canals post-RT. Here we describe the successful management of a pregnancy after abdominal RT (ART). The 34-year-old patient was gravida 1, para 0. When she was 27, she underwent ART for stage Ib1 cervical cancer, and she became pregnant 7 years later. Because her cervical canal was 16.7 mm during early pregnancy, we performed TAC at 12 weeks of pregnancy. Post-surgery, we administered an infusion of ritodrine hydrochloride for tocolysis. A selective caesarean section was performed at 36 weeks, with the delivery of a healthy infant. |
| キーワード | cervical cancer radical trachelectomy pregnancy transabdominal cerclage |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 173 |
| 終了ページ | 176 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015752 |
| JaLCDOI | 10.18926/AMO/56652 |
|---|---|
| フルテキストURL | 73_2_161.pdf |
| 著者 | Okamoto, Sachiyo| Matsuoka, Ken-ichi| Sakamoto, Maiko| Usui, Yoshiaki| Fujiwara, Yuki| Kondo, Takumi| Tani, Katsuma| Saeki, Kyosuke| Meguri, Yusuke| Asada, Noboru| Ennishi, Daisuke| Nishimori, Hisakazu| Fujii, Keiko| Fujii, Nobuharu| Maeda, Yoshinobu| |
| 抄録 | Second allogeneic stem cell transplantation (allo-SCT) is a potentially curative therapy for patients who relapse after first allo-SCT. Human leukocyte antigen (HLA)-haploidentical related donors provide the broad opportunity to conduct second SCT at the appropriate time, but the efficacy of second SCT from haploidentical donors after relapse has not been established. We retrospectively analyzed the records of 33 patients who underwent second SCT. Twenty patients underwent haplo-SCT with low-dose antithymocyte globulin (ATG), and the other 13 patients underwent conventional- SCTs, including HLA-matched related peripheral blood, unrelated bone marrow or cord blood. Three years after the second SCT, the overall survival (OS) and progression-free survival (PFS) of all patients were 32.5% and 23.9%. Multivariate analyses indicated that non-complete response at second SCT, less than 1-year interval to relapse after first- SCT, and total score ≥ 3 on the hematopoietic cell transplantation-specific comorbidity index were significantly associated with a lower PFS rate. The haplo- and conventional- SCT groups showed equivalent results regarding OS, PFS, cumulative incidences of relapse, non-relapse mortality and graft-versus-host disease. The neutropenic period after transplantation was significantly shorter in haplo- SCT than conventional- SCT (10.5 days vs. 16 days, p=0.001). Our analysis revealed that haplo-SCT could be an alternative therapeutic option for relapsed patients after first SCT. |
| キーワード | allogeneic stem cell transplantation haploidentical stem cell transplantation relapse anti-T lymphocyte globulin |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 161 |
| 終了ページ | 171 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015751 |
| JaLCDOI | 10.18926/AMO/56651 |
|---|---|
| フルテキストURL | 73_2_155.pdf |
| 著者 | Minami, Daisuke| Kayatani, Hiroe| Sato, Ken| Fujiwara, Keiichi| Shibayama, Takuo| Yonei, Toshiro| Sato, Toshio| |
| 抄録 | We investigated the clinical characteristics of refractory asthma associated with the effectiveness of bronchial thermoplasty (BT). We retrospectively evaluated data from 10 patients who underwent BT between June 2016 and December 2017 at Okayama Medical Center. The following were measured before and 6 months post-BT: forced expiratory volume in 1.0 s (FEV1), fractional exhaled nitric oxide (FeNO), immunoglobulin E (IgE) level, blood eosinophil counts (Eosi), Asthma Quality of Life Questionnaire (AQLQ) score, and preventive medication use. At baseline, the mean post-bronchodilator FEV1 was 80.9% of the predicted value (range 45.6-115.7%). All patients were being treated with moderate- or high-dose inhaled corticosteroids and long-acting β2 agonists. The AQLQ improved from 4.26±1.67 at baseline to 5.59±0.94 at 6 months post-BT (p<0.05). The %FEV1, FeNO, IgE, and Eosi did not change significantly between baseline and 6 months post-BT. No severe complications were reported. BT was effective for non-allergic and non-eosinophilic in 3 patients, and allergic or eosinophilic in 4 patients. Their AQLQ improved by > 0.5 points post-BT. For both allergic and eosinophilic asthmatics following mepolizumab, BT was not useful. BT was effective for non-allergic and non-eosinophilic or allergic asthmatics, but insufficient for both allergic and eosinophilic following mepolizumab. |
| キーワード | bronchial thermoplasty non-allergic asthma non-eosinophilic asthma airway hyper-responsiveness patient selection |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 155 |
| 終了ページ | 160 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015750 |
| JaLCDOI | 10.18926/AMO/56649 |
|---|---|
| フルテキストURL | 73_2_135.pdf |
| 著者 | Maeba, Takahiro| Yonezawa, Tomoko| Ono, Mitsuaki| Tomono, Yasuko| Heljasvaara, Ritva| Pihlajaniemi, Taina| Inagawa, Kiichi| Oohashi, Toshitaka| |
| 抄録 | The basement membrane (BM) is composed of various extracellular molecules and regulates tissue regeneration and maintenance. Here, we demonstrate that collagen XVIII was spatiotemporally expressed in the BM during skin wound healing in a mouse excisional wound-splinting model. Re-epithelialization was detected at days 3 and 6 post-wounding. The ultrastructure of epidermal BM was discontinuous at day 3, whereas on day 6 a continuous BM was observed in the region proximal to the wound edge. Immunohistochemistry demonstrated that collagen XVIII was deposited in the BM zone beneath newly forming epidermis in day 3 and 6 wounds. Laminin-332, known to be the earliest BM component appearing in wounds, was colocalized with collagen XVIII in the epidermal BM zone at days 3 and 6. The deposition of α1(IV) collagen and nidogen-1 in the epidermal BM zone occurred later than that of collagen XVIII. We also observed the short isoform of collagen XVIII in the epidermal BM zone at day 3 post-wounding. Collectively, our results suggested that collagen XVIII plays a role in the formation of the dermal-epidermal junction during re-epithelialization, and that it is the short isoform that is involved in the early phase of re-epithelialization. |
| キーワード | collagen XVIII basement membrane wound healing re-epithelialization skin |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 135 |
| 終了ページ | 146 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015748 |
| JaLCDOI | 10.18926/AMO/56648 |
|---|---|
| フルテキストURL | 73_2_127.pdf |
| 著者 | Iwasaki, Yukari| Miyahara, Kimiko| Miyatake, Nobuyuki| Nakatsuka, Mikiya| |
| 抄録 | We aimed to clarify the state of thyroid function in female high school long-distance runners. We evaluated the associations between thyroid function and menstrual condition, bone mineral density (BMD), nutritious status, and body composition. The subjects’ height and weight were measured, along with fat percentage, fat mass, muscle mass, and BMD with dual-energy X-ray absorptiometry. A nutrition and dietary survey measured the subjects’ intake of energy and nutrients based on meals provided at the subjects’ dorm for 3 days in July of 2016 and 2017. Blood parameters including thyroid hormone and estradiol were measured. Most of the subjects (81.3%) were underweight (body mass index <18.5). The thyroid hormone free T3 value was decreased, but TSH was not increased and was similar to that observed in individuals with anorexia nervosa. In our subjects, thyroid hormone was associated with BMD and nutritional intake. To improve the menstruation abnormality of female athletes and to increase their bone density, the athletes’ weight should be managed by proper nutrient intake and the maintenance of their thyroid function. |
| キーワード | thyroid function nutritious status female high school long-distance runners bone mineral density menstrual condition |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 127 |
| 終了ページ | 133 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015747 |
| JaLCDOI | 10.18926/AMO/56646 |
|---|---|
| フルテキストURL | 73_2_109.pdf |
| 著者 | Abe, Makoto| Iwamuro, Masaya| Kawahara, Yoshiro| Kanzaki, Hiromitsu| Kawano, Seiji| Tanaka, Takehiro| Tsumura, Munechika| Makino, Takuma| Noda, Yohei| Marunaka, Hidenori| Nishizaki, Kazunori| Okada, Hiroyuki| |
| 抄録 | The efficacy and safety of endoscopic submucosal dissection (ESD) for superficial cancer of the pharynx are still unclear. To identify clinicopathological features of superficial pharyngeal cancer, and the efficacy and safety of ESD, we retrospectively assessed 70 pharyngeal cancers in 59 patients who underwent ESD. Of these patients, 61.0% and 50.8% had a history of esophageal cancer and head and neck cancer, respectively. The median tumor size was 15 mm, and 75.7% of the lesions were located at the piriform sinus. The en bloc resection rate was 94.9%. Treatment-related adverse events occurred in 8 cases, but there was no treatment-related death. The lateral margin was positive for neoplasm in 3 lesions (4.3%) and inconclusive in 27 lesions (38.6%), but no local recurrence was observed. Cervical lymph node metastasis was observed in 6 patients, and was successfully treated by cervical lymph node dissection. The three-year overall survival rate was 91.5% (95%CI: 76.6-97.3%) and the cause-specific survival rate was 97.6% (95%CI: 84.9-99.7%). In conclusion, ESD for superficial pharyngeal cancer was safe and effective. “Resect and watch” is probably a feasible and rational strategy for treatment of patients with superficial pharyngeal cancer. |
| キーワード | endoscopic submucosal dissection superficial cancer pharynx endoscopic resection |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 109 |
| 終了ページ | 115 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015745 |
| JaLCDOI | 10.18926/AMO/56644 |
|---|---|
| フルテキストURL | 73_2_95.pdf |
| 著者 | Ercan, Sabriye| Başkurt, Ferdi| Başkurt, Zeliha| Çetin, Cem| |
| 抄録 | The aim of this study was to examine effect of fatigue levels on functional mobility and balance in middle-aged obese females. The study included 98 healthy females aged 40-60 years with BMI ≥ 30 kg/m2. Self-perceived fatigue was evaluated with a self-administered questionnaire, the Checklist of Individual Strength in Turkish (CIS-T), on which 62.3% of the study subjects identified themselves as fatigued. The body weight and BMI values of fatigued subjects were found to be higher than those of the non-fatigue group (p<0.05). The reported exercise habits of the fatigue group were found to be significantly lower than their non-fatigued peers (p<0.05). The level of functional mobility (Timed Up and Go Test), static balance (One-Legged Stance Test with Eyes Open) and dynamic balance (Functional Reach Test and the 3-meter Timed Tandem Walk Test) were measured, and statistically significant differences were found between fatigue and non-fatigue groups on all of them (p<0.05). In addition, correlations were found between the sub-parameters of the CIS-T scale and the functional tests at |
| キーワード | fatigue obesity mobility balance woman |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-04 |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 95 |
| 終了ページ | 100 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31015743 |
| タイトル（別表記） | The 92th Okayama Chest Disease Conference |
|---|---|
| フルテキストURL | 130_185.pdf |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 185 |
| 終了ページ | 185 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| タイトル（別表記） | The 22nd Annual Meeting of Japanese Association of Cancer Immunology : From the Banquet to the Beginning |
|---|---|
| フルテキストURL | 130_183.pdf |
| 著者 | 鵜殿 平一郎| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 183 |
| 終了ページ | 184 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| フルテキストURL | 130_181_182.pdf |
|---|---|
| 著者 | 布施 春樹| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 181 |
| 終了ページ | 182 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| タイトル（別表記） | Why simulation education：The ultimate method of active learning |
|---|---|
| フルテキストURL | 130_179.pdf |
| 著者 | 万代 康弘| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 179 |
| 終了ページ | 180 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.179 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.179 |
| NAID | 130007542829 |
| タイトル（別表記） | Drug interaction（43. Drug interaction in cutaneous T-cell lymphoma） |
|---|---|
| フルテキストURL | 130_175.pdf |
| 著者 | 田中 雄太| 神崎 浩孝| 森下 陽介| 北村 佳久| 千堂 年昭| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 175 |
| 終了ページ | 178 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.175 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.175 |
| NAID | 130007542850 |
| フルテキストURL | 130_173.pdf |
|---|---|
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 173 |
| 終了ページ | 174 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.173 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.173 |
| NAID | 130007542847 |
| タイトル（別表記） | General Practitioner |
|---|---|
| フルテキストURL | 130_167.pdf |
| 著者 | 小比賀 美香子| 片岡 仁美| 小川 弘子| 大塚 文男| |
| キーワード | 新専門医制度 総合診療専門医 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 167 |
| 終了ページ | 172 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.167 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.167 |
| NAID | 130007542846 |
| タイトル（別表記） | A survey of nurses’ and physicians’ safety awareness in CT/MRI examinations |
|---|---|
| フルテキストURL | 130_161.pdf |
| 著者 | 渡邉 真苗| 松浦 龍太郎| 難波 志穂子| |
| 抄録 | To perform computed tomography （CT）/magnetic resonance imaging （MRI） scans safely and reliably, adherence to a pre-scan checklist is crucial. However, physicians and nurses may differ in their recognition of the usefulness of this checklist. We conducted the present study to investigate possible differences between physicians’ and nurses’ awareness of CT/MRI scan safety in terms of their adherence to the pre-scan checklist. We prepared an independently developed self-administered 23-item questionnaire about attributes of subjects, CT/ MRI scan safety recognition and current situation for CT/MRI examinations. The survey was distributed to 468 participants who combined nurses and physicians at Okayama University Hospitalin Okayama, Japan. We analysis the responses of the 224 participants （117 nurses and 107 physicians）who returned the survey with on missing data （a 65.1% completion rate）. The overall safety recognition scores were significantly higher for the nurses than for the physicians （p＜0.001）. In addition, the physicians did not sufficiently know or implement the guidelines in the CT/MRI scan safety manual used at our hospital. Nurses and physicians demonstrated marked differences in their awareness and knowledge of safety regarding CT/MRI scans. Measures for improving safety recognition should thus be designed for individual healthcare occupations. |
| キーワード | CT/MRI検査（CT/MRI examinations） 安全認識（safety recognition） 職種の差異（difference between occupations） CT/MRI検査マニュアル（CT/MRI examinations manual） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 161 |
| 終了ページ | 166 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.161 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.161 |
| NAID | 130007542844 |
| タイトル（別表記） | Video capsule endoscopy usage: Intra-hospital consultations before and after the expansion of indications |
|---|---|
| フルテキストURL | 130_155.pdf |
| 著者 | 川野 誠司| 岩室 雅也| 井口 俊博| 杉原 雄策| 原田 馨太| 平岡 佐規子| 岡田 裕之| |
| 抄録 | Approximately 10 years have passed since video capsule endoscopy （VCE）was introduced in routine clinical practice in Japan. We started using VCE in January 2009. Here we investigated the contribution of VCE and its level of recognition at our 855-bed hospital. We compared the clinical characteristics of intra-hospital consultation cases with non-consultation cases, and the details of the cases from each of our hospital’s departments. The number of intra-hospital consultations was notably increased by our expansion of the indications for non-obscure gastrointestinal bleeding （OGIB）cases. However, most of our hospital’s departments are sub-departments of internal medicine, in which almost no change in indications has been made. We found that the percentage of OGIB cases was higher among the intra-hospital consultations than non-consultations, and that the OGIB percentages differed markedly among the departments. Especially for OGIB cases, all hospital departments should be better informed regarding the indications for and efficacy of VCE. |
| キーワード | カプセル内視鏡（video capsule endoscopy） 適応拡大（expansion of indication） 院内紹介（intra-hospital consultation） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 155 |
| 終了ページ | 159 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.147 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.147 |
| NAID | 130007542857 |
| タイトル（別表記） | Feasibility evaluation of a remote monitoring system in the home |
|---|---|
| フルテキストURL | 130_147.pdf |
| 著者 | 笠原 真悟| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 147 |
| 終了ページ | 154 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.147 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.147 |
| NAID | 130007542853 |
| タイトル（別表記） | Research on arginase is interesting |
|---|---|
| フルテキストURL | 130_141.pdf |
| 著者 | 荻野 景規| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 141 |
| 終了ページ | 145 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.141 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.141 |
| NAID | 130007542858 |
| タイトル（別表記） | Basic studies on S100-mediated cancer metastasis based on the development of innovative biologics to aim at its effective prevention |
|---|---|
| フルテキストURL | 130_135.pdf |
| 著者 | 阪口 政清| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 135 |
| 終了ページ | 139 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.135 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.135 |
| NAID | 130007542849 |
| タイトル（別表記） | Two Nobel laureates, Alexis Carrel and Peyton Rous, intended to use cells in culture for theirresearch at the beginning of the 20th century |
|---|---|
| フルテキストURL | 130_129.pdf |
| 著者 | 難波 正義| |
| 抄録 | 21世紀になって2017年までに，34件のノーベル生理学・医学賞と化学賞が出ているが，その約半数の研究に培養細胞（動物の細胞，あるいは，イースト）が使われている．すなわち，現代の生命科学の研究には，培養細胞がきわめて大きな役割を果たしているといえる．今回は，今から約100年前，細胞を培養して研究を進めようとした先見性に富んだ 2人のノーベル生理学・医学賞受賞者，Alexis Carrel（以下，本文ではカレルとする）と Peyton Rous（以下，ラウス）の経歴と業績を紹介し，彼等の培養細胞との係りについて述べる． |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2018-12-03 |
| 巻 | 130巻 |
| 号 | 3号 |
| 開始ページ | 129 |
| 終了ページ | 133 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.130.129 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2018 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.130.129 |
| NAID | 130007542837 |