検索結果 19937 件
| タイトル（別表記） | Life of a prostitute from the perspective of the Earned Money Book (Gyoku keisanbo): A Look at “Historical documents related to the brothel（tentative）[Iwakiro,Yamagata Prefecture]” in the collection of the Okayama University Library |
|---|---|
| JaLCDOI | 10.18926/66201 |
| フルテキストURL | jdc_003_299.pdf |
| 著者 | 沢山 美果子| |
| Amo Type | 資料紹介 (Materials and data) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 299 |
| 終了ページ | 307 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | A Meiji person's impression of the petition: What the postscript tells |
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| JaLCDOI | 10.18926/66200 |
| フルテキストURL | jdc_003_290.pdf |
| 著者 | 山下 洋| |
| Amo Type | 資料紹介 (Materials and data) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 290 |
| 終了ページ | 298 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | Water usage, flooding, and the Takao family at Senjū-nakagumi in the Meiji period: A case study of the Minuma substitute canal (Minuma-daiyōsui) |
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| JaLCDOI | 10.18926/66194 |
| フルテキストURL | jdc_003_079.pdf |
| 著者 | 三村 昌司| |
| 抄録 | This paper examines the maintenance work of the Minuma Substitute Canal by the Meiji Government and how Noriyoshi Takao who lived at Senjū-nakagumi was involved in it. In the 1880s, when the cost of maintaining the Minuma Substitute Canal was shifted from government expenditures to private ones, the early modern water usage system was on the verge of being converted to a modern one. This meant that the system, which was based on villages or ryō (領), transformed into one based on individuals, especially landowners. The village served as a cost-sharing unit during the Meiji period. Ryō (領) were operated in the downstream water of the Minuma Substitute Canal where there were no critical structures. However, districts (郡) supervised the water usage of ryō, creating a multilayered local community in terms of water usage. |
| キーワード | water usage floods modern Japan |
| Amo Type | 特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 79 |
| 終了ページ | 91 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | Disaster information and documentation in the Meiji period |
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| JaLCDOI | 10.18926/66193 |
| フルテキストURL | jdc_003_067.pdf |
| 著者 | 天野 真志| |
| 抄録 | This paper focuses on the recording and transmission of disaster information, and examines the accumulation of disaster information, its trends, and the intentions behind its accumulation through a survey of information records accumulated by individuals during the Meiji period. Endō Sanenobu, the subject of this paper, was active mainly in Kyoto during the Meiji period (1868-1912), and in the course of his activities, he accumulated a vast amount of information records called the Seizan Manroku (静山漫録), including records of his investigations of ancient documents handed down in various places and verification records of folk tales and customs passed down in various places. In the course of accumulating such information, he became increasingly interested in disaster information after the Yodogawa river flood in Osaka in 1885, and eventually began to compile a series of Suiin Hikkai（酔蚓筆芥）on disaster information as his main theme. The series of information activities by Sanenobu were also supported by the development and diffusion of information media during that period. At the same time, the fact that Sanenobu paid attention to disaster information among various types of information suggests that he regarded disasters as an important turning point in his understanding of national and social changes. Through this information, the reality of people's social perceptions formed by the media will be revealed. |
| キーワード | the Yodogawa river disaster information information gathering historical awareness |
| Amo Type | 特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 67 |
| 終了ページ | 78 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | The formation of sandbanks and regional transformation in the Late Medieval period |
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| JaLCDOI | 10.18926/66192 |
| フルテキストURL | jdc_003_060.pdf |
| 著者 | 矢田 俊文| |
| 抄録 | The purpose of this paper is to clarify how a harbor city established in a sandbank inlet transformed a local area. In the Later Medieval period, the harbor city of Nakamura was established in the lower part of the Chikusa river. In the late 15th century, the Eiōji temple of Jōdo Shinshū Buddhism was constructed in the harbor city of Nakamura. Nakamura used Sagoshinoshō as a local name. In the 16th century, the harbor city of Kariya on the west coast of the Chikusa river also used the local name of Sagoshinoshō. In the early modern period, villages to the west of the mouth of the Chikusa river came to use the local name of Sagoshinoshō. While the local name of the west coastal area of the Chikusa river mouth had been Akōnoshō, it changed to Sagoshinoshō. Areas where local names may have changed also include Shikatanoshō and Mikuriyanoshō elsewhere in the Later Medieval period. |
| キーワード | sandbank the Chikusa river harbor city temple of Jōdo Shinshū Buddhism local names |
| Amo Type | 特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 60 |
| 終了ページ | 66 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| タイトル（別表記） | Parameter study of strong ground motion simulation for the Median Tectonic Line in the case of the Iyo-Bungo Earthquake of September 1st, 1596 |
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| JaLCDOI | 10.18926/66189 |
| フルテキストURL | jdc_003_021.pdf |
| 著者 | 大熊 祐里英| 隈元 崇| |
| 抄録 | The purpose of this study is to verify the fault length and earthquake magnitude of the Iyo-Bungo earthquake in 1596 estimated by Ishibashi (2019) using historical documents written in the same period. According to Ishibashi (2019), the length of the source fault was estimated to have been less than 100 km and the earthquake magnitude was roughly estimated to have been around 7.5. In order to attempt to reproduce the interpretation, we conducted two different strong ground motion simulations: the attenuation equation method and the characterized source model method, both used in the Headquarters for Earthquake Research Promotion. We simulated earthquake ground motions based on several source fault models including estimation by Ishibashi (2019). For the length of the fault, a 100 km length corresponding to the Iyonada segment of the Median Tectonic Line active fault system was the first model and 130 km and 160 km models extending onshore to the northeast were taken into account as epistemic uncertainties. Regarding the dip angle of the fault, both 40 and 90 degree models were considered also as epistemic uncertainties. Our calculation with other uncertainties shows that the models with a fault length of 100 km with a dip angle of 90 or 40 degrees are consistent with the seismic intensity and seismogenic fault length of offshore fault estimated by Ishibashi (2019) based on reliable first-grade documents. If low-certainty intensity estimates by Ishibashi (2019) are used to evaluate fault length in our calculation, the possibility of 130 or 160 km length models with additional onshore faults will remain. Our results show that the strong ground motion simulation could reinforce the expert’s interpretation of historical documents and propose quantitative source fault models for historical earthquakes. |
| キーワード | Median Tectonic Line 1596 Iyo-Bungo earthquake strong ground motion simulation epistemic uncertainties |
| Amo Type | 論文 (Research article) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 21 |
| 終了ページ | 40 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/66188 |
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| フルテキストURL | jdc_003_001.pdf |
| 著者 | TSURI, Masao| AOO, Ken| |
| 抄録 | Holistic well-being has rapidly developed in the 21st century as a policy measurement tool. Nevertheless, there continue to be some gaps in the literature regarding the interrelation between subjective well-being and other factors, and, regarding disaggregation of the well-being status within a country, by age group, gender, and community. This study first illustrates how the concept of well-being developed from a philosophical and psychological conception of “happiness” to being measured by multidimensional tools that measure the impact of policy and the progress of society, such as OECD’s Better Life Index, UK’s National Well-being Measurement, and Japan’s Well-being Survey and Quality of Life. Subsequently, it analyzes the relationships between subjective well-being and objective variables by comparing the country, regional, and individual datasets. It found that some indicators, such as social relationships, have asymmetric effects on life satisfaction depending on the income level or threshold. In other words, if the income is less than a certain level, the effects of some indicators on life satisfaction are complementary to income, while if the income is above that level, the effects are substitutional. Finally, it estimates these effects and confirms them statistically by using the OECD Regional Statistics. Regarding the relationship between social connection and self-evaluation of life satisfaction rated on a 10-point Likert scale, the base score in the estimation is approximately 5.1 points higher in the lowest quartile group of income. However, the substitution is lower than that of the other groups by approximately -0.061. The coefficient of social connection for the other groups was approximately 0.059, and the lowest group had almost zero coefficients for substitution. |
| キーワード | well-being household income social connection OECD Regional Statistics |
| Amo Type | 論文 (Research article) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2024-03-25 |
| 巻 | 3巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 1 |
| 終了ページ | 20 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | © 2024 by RIDC |
| 論文のバージョン | publisher |
| フルテキストURL | fulltext20231223-01.pdf |
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| 著者 | Matsuo, Toshihiko| Tanaka, Takehiro| Yamada, Kiyoshi| Nose, Motoko| Tanimoto, Yasushi| |
| キーワード | debridement eyelid lacrimal sac Mycobacterium abscessus nontuberculous mycobacteria |
| 発行日 | 2023-12-21 |
| 出版物タイトル | Clinical Case Reports |
| 巻 | 11巻 |
| 号 | 12号 |
| 出版者 | Wiley |
| 開始ページ | e8364 |
| ISSN | 2050-0904 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38130855 |
| DOI | 10.1002/ccr3.8364 |
| Web of Science KeyUT | 001128230600001 |
| 関連URL | isVersionOf https://doi.org/10.1002/ccr3.8364 |
| タイトル（別表記） | A Study on Surrender of Security by Creditor ⑶ : Focused on Creditor’s Duty to Surety in American Law. |
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| フルテキストURL | olj_73_2_134_152.pdf |
| 著者 | 辻 博明| |
| 出版物タイトル | 岡山大學法學會雜誌 |
| 発行日 | 2023-12-22 |
| 巻 | 73巻 |
| 号 | 2号 |
| 開始ページ | 152 |
| 終了ページ | 134 |
| ISSN | 0386-3050 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| フルテキストURL | fulltext20231221-02.pdf |
|---|---|
| 著者 | Li, YaJun| Sun, ZeXu| Kataoka, Noriyuki| Setoguchi, Taro| Hashimoto, Yusuke| Takeuchi, Soichiro| Koga, Shunjo| Hoshi, Kazuhisa| Mizuguchi, Yoshikazu| Matsushita, Tomohiro| Wakita, Takanori| Muraoka, Yuji| Yokoya, Takayoshi| |
| キーワード | photoelectron holography La(O,F)BiS2-x Se x local structure dopant site |
| 備考 | This is the Accepted Manuscript version of an article accepted for publication in Japanese Journal of Applied Physics. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at https://doi.org/10.35848/1347-4065/ad079b.| This fulltext file will be available in Nov. 2024.| |
| 発行日 | 2023-11-21 |
| 出版物タイトル | Japanese Journal of Applied Physics |
| 巻 | 62巻 |
| 号 | 12号 |
| 出版者 | IOP Publishing |
| 開始ページ | 125001 |
| ISSN | 0021-4922 |
| NCID | AA12295836 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Japan Society of Applied Physics |
| 論文のバージョン | author |
| DOI | 10.35848/1347-4065/ad079b |
| Web of Science KeyUT | 001108061600001 |
| 関連URL | isVersionOf https://doi.org/10.35848/1347-4065/ad079b |
| フルテキストURL | fulltext20231221-01.pdf suppl20231221-01.pdf |
|---|---|
| 著者 | Miura, Kizuku| Fujihara, Michiko| Watanabe, Masaki| Takamura, Yuta| Kawasaki, Mayu| Nakano, Shogo| Kakuta, Hiroki| |
| キーワード | RXR Fluorescence Solvatochromism Binding assay |
| 備考 | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Nov. 2025.| |
| 発行日 | 2023-11-15 |
| 出版物タイトル | Bioorganic & Medicinal Chemistry Letters |
| 巻 | 96巻 |
| 出版者 | Elsevier BV |
| 開始ページ | 129536 |
| ISSN | 0960-894X |
| NCID | AA1079577X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Elsevier Ltd. |
| 論文のバージョン | author |
| PubMed ID | 37913851 |
| DOI | 10.1016/j.bmcl.2023.129536 |
| Web of Science KeyUT | 001107680700001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.bmcl.2023.129536 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tadokoro, Koh| Nakada, Yumi| Sasaki, Ryo| Nakano, Yumiko| Yunoki, Taijun| Shin, Kotaro| Taoka, Masataka| Ninomiya, Kiichiro| Nomura, Emi| Takemoto, Mami| Morihara, Ryuta| Yamashita, Toru| |
| キーワード | sarcoidosis myelopathy lung cancer |
| 発行日 | 2023-12-01 |
| 出版物タイトル | Internal Medicine |
| 巻 | 62巻 |
| 号 | 23号 |
| 出版者 | Japanese Society of Internal Medicine |
| 開始ページ | 3531 |
| 終了ページ | 3535 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Japanese Society of Internal Medicine |
| 論文のバージョン | publisher |
| PubMed ID | 37062734 |
| DOI | 10.2169/internalmedicine.0943-22 |
| Web of Science KeyUT | 001115860700001 |
| 関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.0943-22 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tsuji, Kenji| Nakanoh, Hiroyuki| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
| キーワード | microRNA acute kidney injury biomarker mesenchymal stem cell |
| 発行日 | 2023-09-09 |
| 出版物タイトル | Diagnostics |
| 巻 | 13巻 |
| 号 | 18号 |
| 出版者 | MDPI |
| 開始ページ | 2893 |
| ISSN | 2075-4418 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 37761260 |
| DOI | 10.3390/diagnostics13182893 |
| Web of Science KeyUT | 001119215900001 |
| 関連URL | isVersionOf https://doi.org/10.3390/diagnostics13182893 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Shinoda-Ito, Yuki| Hirai, Anna| Omori, Kazuhiro| Ideguchi, Hidetaka| Yamamoto, Hideki| Kato, Fumino| Obata, Kyoichi| Ogawa, Tatsuo| Nakano, Keisuke| Nakadoi, Takato| Katsuyama, Eri| Ibaragi, Soichiro| Yamamoto, Tadashi| Nagatsuka, Hitoshi| Hirasawa, Akira| Takashiba, Shogo| |
| キーワード | Ligneous periodontitis Plasminogen deficiency PLG Behcet's disease Gingival hyperplasia |
| 備考 | The version of record of this article, first published in BMC Oral Health, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12903-023-03586-8| |
| 発行日 | 2023-11-08 |
| 出版物タイトル | BMC Oral Health |
| 巻 | 23巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 843 |
| ISSN | 1472-6831 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 37940896 |
| DOI | 10.1186/s12903-023-03586-8 |
| Web of Science KeyUT | 001101860500001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12903-023-03586-8 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tokumasu, Kazuki| Fujita-Yamashita, Manami| Sunada, Naruhiko| Sakurada, Yasue| Yamamoto, Koichiro| Nakano, Yasuhiro| Matsuda, Yui| Otsuka, Yuki| Hasegawa, Toru| Hagiya, Hideharu| Honda, Hiroyuki| Otsuka, Fumio| |
| キーワード | adverse events COVID-19 SARS-CoV-2 vaccination mRNA vaccine |
| 発行日 | 2023-10-30 |
| 出版物タイトル | Vaccines |
| 巻 | 11巻 |
| 号 | 11号 |
| 出版者 | MDPI |
| 開始ページ | 1661 |
| ISSN | 2076-393X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38005993 |
| DOI | 10.3390/vaccines11111661 |
| Web of Science KeyUT | 001113977600001 |
| 関連URL | isVersionOf https://doi.org/10.3390/vaccines11111661 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Shinoda-Ito, Yuki| Omori, Kazuhiro| Ito, Takashi| Nakayama, Masaaki| Ikeda, Atsushi| Ito, Masahiro| Ohara, Toshiaki| Takashiba, Shogo| |
| キーワード | antimicrobial iron chelator oral infection Streptococcus mutans super-polyphenols |
| 発行日 | 2023-10-24 |
| 出版物タイトル | Antibiotics |
| 巻 | 12巻 |
| 号 | 11号 |
| 出版者 | MDPI |
| 開始ページ | 1562 |
| ISSN | 2079-6382 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 37998764 |
| DOI | 10.3390/antibiotics12111562 |
| Web of Science KeyUT | 001109390500001 |
| 関連URL | isVersionOf https://doi.org/10.3390/antibiotics12111562 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Hagiya, Hideharu| |
| 発行日 | 2023-10-20 |
| 出版物タイトル | PLoS ONE |
| 巻 | 18巻 |
| 号 | 10号 |
| 出版者 | Public Library of Science |
| 開始ページ | e0291677 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Hideharu Hagiya. |
| 論文のバージョン | publisher |
| PubMed ID | 37862317 |
| DOI | 10.1371/journal.pone.0291677 |
| Web of Science KeyUT | 001099217100029 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0291677 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Fiel'ardh, Khalifatulloh| Torkar, Gregor| Rožman, Hana| Fujii, Hiroki| |
| キーワード | sustainable development goals teacher education curricula qualitative content analysis semi-structured interview Japan Slovenia |
| 発行日 | 2023-11-09 |
| 出版物タイトル | Frontiers in Education |
| 巻 | 8巻 |
| 出版者 | Frontiers Media |
| 開始ページ | 1215500 |
| ISSN | 2504-284X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Fiel’ardh, Torkar, Rožman and Fujii. |
| 論文のバージョン | publisher |
| DOI | 10.3389/feduc.2023.1215500 |
| Web of Science KeyUT | 001115240200001 |
| 関連URL | isVersionOf https://doi.org/10.3389/feduc.2023.1215500 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamashita, Toru| Nakano, Yumiko| Sasaki, Ryo| Tadokoro, Koh| Omote, Yoshio| Yunoki, Taijun| Kawahara, Yuko| Matsumoto, Namiko| Taira, Yuki| Matsuoka, Chika| Morihara, Ryuta| Abe, Koji| |
| キーワード | amyotrophic lateral sclerosis clinical trial CL2020 multilineage-differentiating stress-enduring (Muse) cells intravenous administration |
| 発行日 | 2023 |
| 出版物タイトル | Cell Transplantation |
| 巻 | 32巻 |
| 出版者 | SAGE Publications |
| ISSN | 0963-6897 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 38014622 |
| DOI | 10.1177/09636897231214370 |
| Web of Science KeyUT | 001109624600001 |
| 関連URL | isVersionOf https://doi.org/10.1177/09636897231214370 |
| JaLCDOI | 10.18926/AMO/66161 |
|---|---|
| フルテキストURL | 77_6_671.pdf |
| 著者 | Minami, Daisuke| Hosoya, Takeshi| Hosoya, Masaharu| Nagano, Akichika| Nakajima, Yasuhiro| Miyahara, Nobuaki| Kanehiro, Arihiko| |
| 抄録 | A 74-year-old Japanese woman presented with a 45-year history of refractory asthma. She had been treated with inhaled corticosteroids, a long-acting β2-agonist, and a long-acting muscarinic antagonist for 6 months. She also had a repeated viral infection. Her condition had been characterized as a refractory asthma associated with type 2 and non-type 2 traits. We began treatment with tezepelumab. The control of the patient’s asthma symptoms and quality of life improved greatly within 1 month (changes in eosinophil count from 748 to 96 /μL, in FeNO from 32 to 17 ppb, in the Asthma Quality of Life Questionnaire score from 3.59 to 6.68, and in the Asthma Control Test score from 13 to 23). Tezepelumab was effective as an initial biologic agent for a patient with refractory asthma associated with type 2 and non-type 2 traits. |
| キーワード | tezepelumab biologic agent eosinophilic non-type 2 severe asthma |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 671 |
| 終了ページ | 674 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145943 |
| Web of Science KeyUT | 001164631200014 |